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KUROKI Shouji  黒木 祥司

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KUROKI Syoji  黒木 祥司

黒木 祥二  クロキ ショウジ

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Researcher Number 30215090
Other IDs
Affiliation (based on the past Project Information) *help 2005 – 2006: 九州大学, 大学病院, 講師
2003: Kyushu University Hospital, Lecturer, 大学病院, 講師
2002: 九州大学, 医学部附属病院, 講師
2000 – 2001: 九州大学, 医学部・付属病院, 講師
2000 – 2001: 九州大学, 医学部・附属病院, 講師
1997 – 1999: 九州大学, 医学部, 講師
1991 – 1996: 九州大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Digestive surgery / General surgery
Except Principal Investigator
Digestive surgery / General surgery / General surgery
Keywords
Principal Investigator
胆汁酸合成 / bile acid synthesis / 7αヒドロキシコレステロール / 肝予備能 / rat / regulation mechanism / bile acid metabolism / ラット / 調節機構 / 胆汁酸代謝 … More / 腸管因子 / cholestyramine / hepatic functional reserve / 負荷試験 / コレスチラミン / Intercellular transmission / Vaccine therapy / Artificial antigens / Functional molecules / Gene transfer / Exosomes / Breast cancer / 伝達物質 / 制御性T細胞 / 遺伝子治療 / 細胞間伝達 / ワクチン療法 / 人工抗原 / 機能分子 / 遺伝子導入 / エキソゾーム / 乳癌 / intestinal factor / cholesterol 7α-hydroxylase / コレステロール7α酸化酵素 / コレステロール7α水酸化酵素 / intestinal facor / 7α-hydroxycholesterol / liver regeneration / hepatectomy / 7α -hydroxycholesterol / 肝切除 / liver cirrhosis / chronic hepatitis / 7 alpha-hydroxycholesterol / 慢性肝疾患 / 肝硬変 / 慢性肝炎 / BILE FLOW / BILIARY DRAINAGE / OBSTRUCTIVE JAUNDICE / HEPATIC RESERVE / 7alpha-HYDROXYCHOLESTEROL / BILE ACID SYNTHESIS / 7alphaヒドロキシコレステロール / 胆汁流量 / 減黄 / 閉塞性黄疸 / Oxi-cholesterolalveol / Bile acid synthesis / 7alpha-Hydroxycholesterol / Carcinogenesis / Cholesterol / コレステロ-ル酸化物 / 7αーhydroxycholesterol / コレステロ-ル / 酸化コレステロール / 胆汁酸生合成 / 7α-水酸化コレステロール / 発癌 / コレステロール … More
Except Principal Investigator
ビリルビン / 閉塞性黄疸 / bilirubin / 肝再生 / Liver regeneration / 肝切除 / low cell / CD44+24- / side population / cancer stem cell / 尿 / 抗酸化剤 / 酸化ストレス / oxidative stress / sepsis / 活性酸素 / 敗血症 / biliary drainage / obstructive jaundice / 減黄術 / Obstructive jaundice / Fibronectin / Liver cirrhosis / フィブロネクチン / 血中ケトン体比 / 肝硬変 / estroren receptor / morphogenesis signais / anticancer-drug resistant / breast cancer / エストロゲン・レセプター / 形態形成シグナル / 薬剤耐性 / 乳癌 / 8-hydroxy deoxyguanosine / acrolein / lipid peroxides / biopyrrin / jaundice / hyperbaric oxygen / superoxide / 高圧酸素療法 / 黄疸 / 8水酸化デオキシグアノシン / アクロレイン / 過酸化脂質 / バイオピリン / 黄疽 / 高圧酸素 / Transcriptional factor / Cell cycle / Cyclin dependent kinase / Cyclin / Biliary drainage / 転写因子AP-1 / EBP / 転写因子C / MAPキナーゼ / 増殖因子 / サイクリンE / 萎縮 / 門脈結紮術 / 腸管内胆汁 / 転写因子 / 細胞周期 / サイクリン依存性キナーゼ / サイクリン / 肝切除後肝再生 / 胆汁瘻 / complication / surgery / severity / urine / antioxidant / 合併症 / 外科手術 / 重症度 / reperfusion injury / ischemia / gadolinium / hepatectomy / 他臓器合併肝切除 / 肝予備能 / Kupffer細胞 / 他臓器合併切除 / 虚血再灌流障害 / ガドリニウム / 肝切除術 / heme oxygenase / intestine / ヘムオキシゲナーゼ / 小腸 / delta-bilirubin / 肝機能 / 胆汁外瘻 / デルタビリルビン / Selective portal occlusion / Cholesterol 7alpha-hydroxylase / Serum 7alpha-hydroxycholesterol / Hepatic energy charge / AKBR / 7alpha-hydroxycholesterol / DNA合成 / エネルギー代謝 / 門脈部分閉塞 / 部分門脈閉塞 / 血中7α-hydroxycholesterol / Cholesterol 7α-hydroxylase活性 / 肝エネルギーチャージ / Reticuloendothelial system / Microsome / 7エア / Mitochondria / Arterial ketone body ratio-hydroxycholesterol / Hepatectomy / 7αーhydroxycholesterol / ケトン体 / 網内系 / ミクロゾーム / 7a-hydroxycholesterol / ミトコンドリア Less
  • Research Projects

    (16 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (25 People)
  •  Development of the new strategy by cancer stem cell-targeted therapy for patients with breast cancer

    • Principal Investigator
      KUBO Makoto
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Development of the breast cancer therapy using intercellular transmission by small vesicle (Exosomes) having fusion facultyPrincipal Investigator

    • Principal Investigator
      KUROKI Shouji
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Molecular biological mechanism for regulation of bile acid synthesis can explain bile acid synthesis under interrupted enterohepatic circulation in vivo?Principal Investigator

    • Principal Investigator
      KUROKI Syoji
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Effect of hyperbaric oxygen on hyperbiliri.ibinemia from the viewpoint of antioxidant activity of bilirubin

    • Principal Investigator
      SHIMIZU Shuji
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Investigation on the intestinal factor(s) of regulational mechanism of bile acid synthesisPrincipal Investigator

    • Principal Investigator
      KUROKI Shoji
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Increased urinary excretion of bilirubin oxidative metabolites in septic patients: a new marker for ocidative stress in vivo

    • Principal Investigator
      SHIMIZU Shuji
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Establishment of hepatic reserve function and molecular biological analysis of liver function after hepatectomy

    • Principal Investigator
      CHIJIIWA Kazuo
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Miyazaki Medical College
      Kyushu University
  •  Clinical significance of serum 7α-hydroxycholesterol level and hepatic functional reserve in patients who undergo partial hepatectomyPrincipal Investigator

    • Principal Investigator
      KUROKI Syoji
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  The induction of heme oxygenese-1 in intestinal mucosa of septic rat

    • Principal Investigator
      SHIMIZU Shuji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  The total evaluation of the functions of microsome, mitochondria, and reticuloendothelial systems in the liver

    • Principal Investigator
      CHIJIIWA Kazuo
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Clinical significance of serum 7 alpha-hydroxycholesterol level and hepatic functional reserve in patients with chronic liver diseasesPrincipal Investigator

    • Principal Investigator
      KUROKI Syoji
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Clinical significance of serum delta bilirubin during obstructive jandice.

    • Principal Investigator
      CHIJIIWA Kazuo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  SERUM 7 alpha-HYDROXYCHOLESTEROL AS AN INDICATOR OF HEPATIC FUNCTION IN SURGICAL PATIENTS WITH LIVER DISEASESPrincipal Investigator

    • Principal Investigator
      KUROKI Shoji
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Hepatic reserve function assesed by integrated liver components : Mitochondrial, microsomal and reticuloendothelial system.

    • Principal Investigator
      CHIJIIWA Kazuo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Metabolism of intravenously administered 7alpha -hydroxycholesterol-3beta-stearate in the hamster.Principal Investigator

    • Principal Investigator
      KUROKI Syoji
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  New evaluation of hepatic function before and hepatectomy:Total evaluation of the functions mitochodria,microsome and reticuloendothelial system.

    • Principal Investigator
      CHIJIIWA Kazuo
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY

All 2008 2007 2005

All Journal Article

  • [Journal Article] Novel Link between Estrogen Receptor a and Hedgehog Pathway in Breast Cancer2008

    • Author(s)
      Koga, K, Nakamura, M, Nakashima, H, Akiyoshi, T, Kubo, M, Sato, N, Kuroki, S, Nomura, M, Tanaka, M, Katano, M
    • Journal Title

      Anticancer Res (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591439
  • [Journal Article] A New Therapeutic Target of Breast Cancer2007

    • Author(s)
      Kubo, M, Kuroki, S, Tanaka, M
    • Journal Title

      Nihon rinsh 65(6)

      Pages: 142-147

    • NAID

      40015531653

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591439
  • [Journal Article] Effects ofdocetaxelonantigen presentation- related functions of human monocyte-derived dendritic cells.2005

    • Author(s)
      Nakashima H, Tasaki A, Kubo M, Kuroki H, Matsumoto K, Tanaka M, Nakamura M, Morisaki T, Katano M.
    • Journal Title

      Cancer Immunol Pharmacol 55

      Pages: 479-487

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591339
  • [Journal Article] Evaluation of a dysfunctional and short-lived subset of monocyte-derived dendritic cells from cancer patients.2005

    • Author(s)
      Onishi H, Morisaki T, Kuroki H, Matsumoto K, Baba E, Kuga H, Tanaka M, Katano M.
    • Journal Title

      Anticancer Res 25

      Pages: 3445-3451

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591339
  • [Journal Article] Purification, characterization and biologic significance of tumor-derived exosomes2005

    • Author(s)
      Koga K, Matsumoto K, Akiyoshi T, Kubo M, Yamanaka N, Tasaki A, Nakashima H, Nakamura M, Kuroki S, Tanaka M, Katano M.
    • Journal Title

      Anticancer Research 25

      Pages: 3703-3708

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591339
  • [Journal Article] Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production.2005

    • Author(s)
      Kubo M, Morisaki T, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Matsumoto K, Nakamura K, Nakamura M, Katano M.
    • Journal Title

      Cancer Immunol Immunother 54

      Pages: 468-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591339
  • 1.  CHIJIIWA Kazuo (90179945)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 2.  SHIMIZU Shuji (70274454)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  YAMAGUCHI Koji (50191226)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  NAKANO Kenji (00315061)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  MAKINO Ichiro (30347059)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  ICHIMIYA Hitoshi (10183170)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  NOSHIRO Hirokazu (90301340)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  YAMAGUCHI Tokio (30134745)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  OKAMOTO Shuichiro
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  YAMASHITA Hiroyuki (60253449)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KUBO Makoto (60403961)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 12.  HIGASHIJIMA Hidetaka
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  KAMEOKA Nobuhisa
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  KAI Masahiro (40264379)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KONDO Kazuhiro (10244196)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OHSHIMA Akira (70335959)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  NAKAMURA Masafumi (30372741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 18.  MORISAKI Takashi (90291517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 19.  KOJIMA Masasyuki (90380394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  AKASHI Kouichi (80380385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  FUKUSHIMA Kazuhisa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  UEDA Junji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  岸仲 正則
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  高松 祐治
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  高松 裕治
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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