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MIYATAKE Shoichiro  宮武 昌一郎

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… Alternative Names

MIYATAKE Syouitirou  宮武 昌一郎

宮武 晶一郎  ミヤタケ ショウイチロウ

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Researcher Number 30239420
Affiliation (based on the past Project Information) *help 2018 – 2020: 麻布大学, 生命・環境科学部, 教授
2016: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員
2014 – 2015: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 副参事研究員
2012: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 副参事研究員
2011: 財団法人東京都医学総合研究所, ゲノム医科学研究分野, 副参事研究員 … More
2010: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 副参事研究員
2008: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 副参事研究員
2007 – 2008: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 副参事研究員
2007: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 副参事
2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 副参事研究員
2004: Tokyo Metropolitan Organization For medical Research Tokyo Metropolitan Institute of Medical Science, Dept Immunology, Laboratory head, 東京都臨床医学総合研究, 副参事研究員
2004: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 副参事研究員
2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 副参事研究員
2002 – 2004: (財)東京都医学研究機構, 東京都臨床医学研究所, 副参事研究員
2003: 東京都医学研究機構, 東京都臨床医学総合研究所, 副参事研究員
2001: Department of Immunology, Tokyo Metropolitan Institute of Medical Science, Researcher, 免疫研究部門, 副参事研究員
1997: 千葉大, 医学部, 講師
1996: 千葉大学, 医学部, 講師
1995: 千葉大学, 医科部, 助手
1992 – 1995: 千葉大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General medical chemistry / Biological Sciences / Immunology / Basic Section 49070:Immunology-related / Immunology / 分子細胞生物学
Except Principal Investigator
Immunology / Circulatory organs internal medicine / Functional biochemistry / Molecular biology / Functional biochemistry / Biological Sciences
Keywords
Principal Investigator
GATA3 / 転写因子 / ZNF131 / Th2 / T細胞 / サイトカイン / dermatitis / immune checkpoint / CD8+ T cell / LAG3 … More / MHC class II / MC903 / カルシポトリオール / CTL / 免疫チェックポイント / 皮膚炎 / 細胞増殖 / 線維芽細胞 / p21 / B細胞 / BTB Znフィンガー / エピジェネティックス / 細胞分化 / epigenetics / Zbtb35(ZNF131) / RCOR1 / ゲノム医化学 / DNAメチルトランスフェラーゼ / DNA メチルトランスフェラーゼ / Th1 / DNAメチル化 / FACT / CNS / 複製蛋白質 / 遺伝子間領域 / 遣伝子間領域 / 複製タイミング / 複製起点 / 免疫学 / 発生・分化 / CTLA4 / CD28 / レトロウイルスベクター / ZAP70 / プロテアゾームインヒビター / T細胞クローン / TCR-CD3複合体 / DETC / IEL / FcRγ鎖欠損マウス / ζ鎖欠損マウス / GM-CSF / シグナル伝達系 / T細胞活性化 / リンフォカイン / 転写制御 … More
Except Principal Investigator
Cdc7キナーゼ / DNA複製 / 複製起点 / NFAT / TCR / Jak3 / アビディティーモデル / ノックアウトマウス / T細胞分化 / シグナル伝達 / T細胞レセプター / リン酸化 / MCMタンパク質 / チェックポイント制御 / DNAヘリカーゼ / 複製タイミング / 細胞周期 / 転写因子 / G1アレスト / cardiachypertrophy / alpherscreen / transcription factor / calcineurin / 分子間相互作用 / カリシニューリン / 心筋細胞 / 心肥大 / アルファースクリーン / カルシニューリン / initiation of DNA replication / cytokine cluster region / cell cycle / Cdk / ES Cells / replication origins / Cdc7 kinase / G1-S transition / スレオニンキナーゼ / セリン / S移行 / G1 / サイトカイン遺伝子領域 / サイクリン依存性キナーゼ / DNA複製開始 / DNA複製起点 / マウス胚性幹細胞 / サイトカイン依存性キナーゼ / MCM2 / Cdcキナーゼ / T cell differentiation / negative selection / positive / CD3gamma / calnexin / pre-TCR complex / Signal transduction / TCR-CD3複合体 / 遺伝子欠損マウス / 分化 / T細胞 / DC3γ / T細胞文化 / ポジティブ・ネガティブ選択 / CD3γ / カルネキシン / プレTCR複合体 / signal transduction / knock out mice / topoisomerase II / cell growth inhibition / T cell development / CD3 binding molecule / CD3 signal motif / T cell receptor / λgt11 / トポイソメラーゼ / 蛋白プローブ / クローニング / CD3ε / 活性化モチーフ / サイクリンD3 / トポイソメラーゼllβ / 細胞内シグナル伝達 / トポイソメラーゼII / 細胞増殖阻害 / CD3結合分子 / CD3シグナルモチーフ / Tyrosine phosphorylation / PLCgamma1 / Signaling motif / TCRbeta dimer expression / CD3zeta family molecules / Intracellular signal transduction mechanism / CD3 complex / T cell antigen receptor / ζダイマーレセプター / シグナルモチーフ / チロシンキナーゼ / ζファミリー分子 / CD3ξファミリー分子 / チロシンリン酸化 / PLCγ1 / シグナル伝達モチーフ / β鎖単独発現 / CD3ζファミリー分子 / 細胞内シグナル伝達機構 / CD3複合体 / T細胞抗原レセプター / 構造解析 / 染色体ダイナミクス / 染色体DNA複製 / 脳発生 / 細胞分裂 / 乗り越えDNA合成 / 減数分裂期組換え / チェックポイント / 染色体DNA複製開始 / 遺伝子の情報発現と複製 / ポリオーマウイルス / 複製ファクトリー / 真核細胞 / 核構造 / クロマチン構造 / クロマチン / 生体分子 / クロマチン高次構造 / 染色体複製 / アポトーシス / Fas / 腫瘍T細胞 / 増殖阻害 / サイクリン Less
  • Research Projects

    (19 results)
  • Research Products

    (78 results)
  • Co-Researchers

    (29 People)
  •  Immune checkpoint pathways function between MHC class II and CD8+ T cellsPrincipal Investigator

    • Principal Investigator
      MIYATAKE Shoichiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Azabu University
  •  ZNF131, a novel partner molecule of the transcription factor GATA3Principal Investigator

    • Principal Investigator
      MIYATAKE Shoichiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Epigenetic regulation by transceiption factor GATA3Principal Investigator

    • Principal Investigator
      MIYATAKE Shoichiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      公益財団法人東京都医学総合研究所
      Tokyo Metropolitan Organization for Medical Research
  •  Mechanism of lineage commitment by GATA3 - RNA polymeraseII, FACT complex and DNA demethylationPrincipal Investigator

    • Principal Investigator
      MIYATAKE Shoichiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  新規哺乳動物細胞複製起点oriIL-13の選択にかかわる染色体制御機構Principal Investigator

    • Principal Investigator
      宮武 昌一郎
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Elucidation of DNA replication program in mammalian cells

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  転写因子による細胞系列の決定および維持の染色体制御機構Principal Investigator

    • Principal Investigator
      宮武 昌一郎
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Study of the mechanism of cardiac hypertrophy induction by calcium signal and an attept to establish a procedure to regulate cardiac hypertrophy

    • Principal Investigator
      MIYATAKE Yoshiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      TSURUMI UNIVERSITY
  •  クロマチン構造および転写因子による染色体複製の制御機構の研究

    • Principal Investigator
      村上 洋太
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Joint study on DNA replication and checkpoint control

    • Principal Investigator
      ARAI Ken-ichi, 正井 久雄
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  T細胞の機能発現と分化におけるTCRシグナルとサイトカインシグナルの相互作用Principal Investigator

    • Principal Investigator
      宮武 昌一郎
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Chiba University
  •  T細胞受容体シグナルによるJAK-STATシステムの制御機構Principal Investigator

    • Principal Investigator
      宮武 昌一郎
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Chiba University
  •  Regulation of T cell differentiation and selection by TCR signals.

    • Principal Investigator
      SAITO Takashi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Chiba University
  •  T細胞受容体複合体分子の標的組換えマウスを用いた免疫系の発生分化の分子機構Principal Investigator

    • Principal Investigator
      宮武 昌一郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  Mechanism of signal transduction through activation motifs of the T cell receptor complex

    • Principal Investigator
      SAITO Takashi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Chiba University
  •  腫瘍細胞における細胞周期の制御と増殖阻害の分子機構

    • Principal Investigator
      SAITO Takashi
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Chiba University
  •  抗原によるT細胞活性化にともなう遺伝子発現の誘導制御機構Principal Investigator

    • Principal Investigator
      宮武 昌一郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      分子細胞生物学
    • Research Institution
      Chiba University
  •  Structure of and signal transduction through T cell receptor complex

    • Principal Investigator
      SAITO Takashi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      CHIBA UNIVERSITY

All 2019 2018 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2004 Other

All Journal Article Presentation Book

  • [Book] Advances in Hematopoietic Stem Cell Research, Interferon regulatory factor-2 regulates hematopoietic stem cells in mouse bone marrow(R.P.Camacho (ed.))2012

    • Author(s)
      Masumi, A., Takizawa, K., Mizukami, T., Kuramitsu, M., Momose, H., Miyatake, S., Kohno, T., Matsuyama, T., Yamaguchi, K., Hamaguchi, I.
    • Total Pages
      464
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Book] Th2分化制御メカニズム 細胞工学「T細胞サブセット : どこまで感染症や免疫疾患との関わりが理解されてきたのか?」2008

    • Author(s)
      青木和久、宮武昌一郎
    • Publisher
      秀潤社
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Book] サイトカインのエピゲネティック調節 臨床免疫・アレルギー科2008

    • Author(s)
      青木和久、宮武昌一郎
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] A BTB-ZF protein, ZNF131, is required for early B cell development2018

    • Author(s)
      Iguchi T, Miyauchi E, Watanabe S, Masai H, Miyatake S
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 501 Issue: 2 Pages: 570-575

    • DOI

      10.1016/j.bbrc.2018.05.044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07185, KAKENHI-PROJECT-16K14675, KAKENHI-PROJECT-17H01418
  • [Journal Article] BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells.2015

    • Author(s)
      Iguchi T, Aoki K, Ikawa T, Taoka M, Taya C, Yoshitani H, Toma-Hirano M, Koiwai O, Isobe T, Kawamoto H, Masai H, Miyatake S.
    • Journal Title

      The Journal of Immunology

      Volume: 195 Issue: 3 Pages: 982-93

    • DOI

      10.4049/jimmunol.1500602

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460585, KAKENHI-PUBLICLY-26114723, KAKENHI-PROJECT-25650014, KAKENHI-PROJECT-26670472, KAKENHI-PROJECT-26293229, KAKENHI-PROJECT-26251004
  • [Journal Article] Interferon regulatory factor-2 regulates hematopoietic stem cells in mouse bone marrow2012

    • Author(s)
      Masumi, A., Miyatake, S., Kohno, T. and Matsuyama, T
    • Journal Title

      In Advances in Hematopoietic Stem Cell Research (ed. Pelayo, R.)

      Volume: (InTech) Pages: 91-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Journal Article] The enhancer HS2 critically regulates GATA -3-mediated Il4 transcription in T(H)2 cells2011

    • Author(s)
      Tanaka, S., Motomura, Y., Suzuki, Y., Yagi, R., Inoue, H.,Miyatake, S., and Kubo M
    • Journal Title

      Nat Immunol

      Volume: 12 Pages: 77-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Journal Article] The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells.2011

    • Author(s)
      Tanaka, S., Motomura, Y., Suzuki, Y., Yagi, R., Inoue, H., Miyatake, S., Kubo M.
    • Journal Title

      Nature Immunology

      Volume: 12 Pages: 77-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Journal Article] Selective down-regulation of Th2 cytokines by C-terminal binding protein 2 in human T cells2010

    • Author(s)
      Kitamura, F., Kitamura, N., Mori, A., Tatsumi, H., Nemoto, S., Miyoshi, H., Miyatake, S., Hiroi, T. and Kaminuma, O
    • Journal Title

      Int. Arch. Aller gy Immunol

      Volume: 152(Suppl 1) Pages: 18-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Journal Article] Selective down-regulation of Th2 cytokines by C-terminal binding protein 2 in human T cells.2010

    • Author(s)
      Kitamura, F., Kitamura, N., Mori, A., Tatsumi, H., Nemoto, S., Miyoshi, H., Miyatake, S., Hiroi, T., Kaminuma, O.
    • Journal Title

      International Archives of Allergy and Immunology

      Volume: 152 Pages: 18-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Journal Article] Regulation of DNA demethylation during maturation of CD4+ naive T cells by the conserved non-coding sequence CNS-12009

    • Author(s)
      Aoki, K., Sato, N., Yamaguchi, A., Kaminuma, O., Hosozawa, T., Miyatake, S
    • Journal Title

      The Journal of Immunology (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] T-box 21 transcription factor is responsible for distorted T(H)2 differentiation in human peripheral CD4+ T cells.2009

    • Author(s)
      Kaminuma, O., Kitamura, F., Miyatake, S., Yamaoka, K., Miyoshi, H., Inokuma, S., Tatsumi, H., Nemoto, S., Kitamura, N., Mori, A., and Hiroi, T.
    • Journal Title

      J. Allergy Clin. Immunol. 123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Ly49Q ligand expressed by activated B cells induces plasmacytoid DC maturation.2009

    • Author(s)
      Toma-Hirano, M., Namiki, S., Shibata, Y., Ishida, K., Arase, H., Miyatake, S., Arai, K. and Kamogawa-Schifter, Y.
    • Journal Title

      Eur. J. Immunol. 39

      Pages: 1344-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Downregulation of IL-13 gene transcription by T-bet in human T cells.2008

    • Author(s)
      Suzuki, K., Kaminuma, O., Hiroi, T., Kitamura, F., Miyatake, S., Takaiwa, F., Tatsumi, H., Nemoto, S., Kitamura, N. and Mori, A.
    • Journal Title

      Int. Arch. Allergy Immunol. 146 Suppl 1

      Pages: 33-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Airway eosinophilic inflammation is attenuated in conserved noncoding sequence-1 deficient mice.2008

    • Author(s)
      Ohtomo, T., Miyatake, S., Kajiyama, Y., Umezu-Gotoa, M., Kaminuma, O. and Mori, A.
    • Journal Title

      Int. Arch. Allergy Immunol. 146 Suppl 1

      Pages: 2-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article]2008

    • Author(s)
      青木和久, 宮武昌一郎
    • Journal Title

      Th2分化制御メカニズム細胞工学(秀潤社)

    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Differential Contribution of NFATc2 and NFATc1 to TNF-α Gene Expression in T Cells.2008

    • Author(s)
      Kaminuma, O., Kitamura, F., Kitamura, N., Hiroi, T., Miyoshi, H., Miyawaki, A., Miyatake, S.
    • Journal Title

      J. Immunol. 180

      Pages: 1319-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] The role of CD11b in phagocytosis and dendritic cell development.2008

    • Author(s)
      Chen, J., Namiki, S., Toma-Hirano, M., Miyatake, S., Ishida, K., Shibata, Y., Arai, N., Arai, K., and Kamogawa-Schifter, Y.
    • Journal Title

      Immunol. Lett. 120

      Pages: 42-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Cyclic AMP-induced chromatin changes support the NFATc-mediated recruitment of GATA-3 to the interleukin 5 promoter.2008

    • Author(s)
      Klein-Hessling, S., Bopp, T., Jha, M.K., Schmidt, A., Miyatake, S., Schmitt, E. and Serfling, E.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 31030-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article]2008

    • Author(s)
      青木和久, 宮武昌一郎
    • Journal Title

      サイトカイン遺伝子におけるクロマチン制御機構 臨床免疫・アレルギー科(科学評論社)

    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Cyclic AMP-induced chromatin changes support the NFATc-mediated recruitment of GATA-3 to the interleukin 5 promoter2008

    • Author(s)
      Klein-Hessling, S., Bopp, T., Jha, M. K., Schmidt, A., Miyatake, S., Schmitt, E. Serfling, E
    • Journal Title

      The Journal of Biological Chemistry 283

      Pages: 31030-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Differential Contribution of NFATc2 and NFATc1 to TNF-α Gene Expression in T Cells.2008

    • Author(s)
      Kaminuma O., Kitamura F., Kitamura N., Hiroi T., Miyoshi H., Miyawaki A., Miyatake S
    • Journal Title

      The Journal of Immunology 180

      Pages: 1319-1326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Differential Contribution of NFATc2 and NFATc1 to TNF-α Gene Expression in T Cells2008

    • Author(s)
      Kaminuma O, Kitamura F, Kitamura N, Hiroi T, Miyoshi H, Miyawaki A, Miyatake S
    • Journal Title

      The Journal of Immunology 180

      Pages: 1319-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] IL-4 gene transcription in human T cells is suppressed by T-bet. Int. Arch.2007

    • Author(s)
      Kitamura, N., Kitamura, F., Kaminuma, O., Miyatake, S., Tatsumi, H., Nemoto, S. and Mori, A.
    • Journal Title

      Allergy Immunol. 143 Suppl

      Pages: 68-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Type I interferon regulates pDC maturation and Ly49Q expression.2007

    • Author(s)
      Toma-Hirano, M., Namiki, S., Miyatake, S., Arai, K. and Kamogawa-Schifter, Y.
    • Journal Title

      Eur. J. Immunol. 37

      Pages: 2707-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Journal Article] Replication initiation from a novel origin identified in the Th2 cytokine cluster locus requires a distant conserved noncoding sequence.2006

    • Author(s)
      Hayashida, T., Oda, M., Ohsawa, K., Yamaguchi, A., Hosozawa, T., Locksley, R.M., Giacca, M., Masai, H., Miyatake, S.
    • Journal Title

      The Journal of Immunology 176

      Pages: 5446-5454

    • Data Source
      KAKENHI-PROJECT-18058024
  • [Journal Article] Replication initiation from a novel origin identified in the Th2 cytokine cluster locus requires a distant conserved non-coding sequence.2006

    • Author(s)
      Hayashida, T., Oda, M., Ohsawa K.,Yamaguchi A., Giacca, M., Locksley,R.M., Masai, H., and Miyatake, S.
    • Journal Title

      J. Immunol. 176

      Pages: 5446-5454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18207009
  • [Journal Article] GATA-3 suppresses IFN-γ promoter activity independently of binding to cis-regulatory elements.2004

    • Author(s)
      Kaminuma, O., Kitamura, F., Kitamura, N., Miyagishi, M., Taira, K., Yamamoto, K., Miura, O., Miyatake, S
    • Journal Title

      FEBS lett. 570

      Pages: 53-58

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590776
  • [Journal Article] GATA-3 suppresses IFN-γ promoter activity independently of binding to cis-regulatory elements.2004

    • Author(s)
      Kaminuma, O., Kitamura, F., Kitamura, N., Miyagishi, M., Taira, K., Yamamoto, K., Miura, O., Miyatake, S.
    • Journal Title

      FEBS Lett. 570

      Pages: 53-58

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590776
  • [Journal Article] GATA-3 suppresses IFN-γ promoter activity independently of binding to cis-regulatory elements.2004

    • Author(s)
      Kaminuma, O., Kitamura, F., Kitamura, N., Miyagishi, M., Taira K., Yamamoto, K., Miura, O., Miyatake, S.
    • Journal Title

      FEBS Letter 570

      Pages: 53-58

    • Data Source
      KAKENHI-PROJECT-15590776
  • [Journal Article] GATA-3 suppresses IFN-γ promoter activity independently of binding to cis-regulatory elements.2004

    • Author(s)
      Kaminuma, O., Kitamura, F., Kiramura, N., Miyagishi, M., Taira, K., Yamamoto, K., Miura, O., Miyatake, S.
    • Journal Title

      FEBS Lett. 570

      Pages: 53-58

    • Data Source
      KAKENHI-PROJECT-16043263
  • [Journal Article] Regulation of DNA demethylation during maturation of CD4+ naive T cells by the conserved non-coding sequence CNS-1.

    • Author(s)
      Aoki, K., Sato, N., Yamaguchi, A., Kaminuma, O., Hosozawa, T. and Miyatake, S.
    • Journal Title

      J. Immunol. (印刷中)

      Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] ZNF131, one of BTB ZF protein family members, is required for the early signaling of T cell activation through the MTOC formation and relocation2019

    • Author(s)
      Iguchi, T., Masai, H., Miyatake, S.
    • Organizer
      The 48th Annual Meeting of the Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-18K07185
  • [Presentation] ZNF131, one of BTB ZF protein family members, is required for proliferation as well as activation of both T and B lymphocytes2018

    • Author(s)
      Tomohiro Iguchi, Hisao Masai, Shoichiro Miyatake
    • Organizer
      Japanese Sciety for Immunology
    • Data Source
      KAKENHI-PROJECT-18K07185
  • [Presentation] GATA3変異マウスで発症する自己免疫性皮膚炎2016

    • Author(s)
      坂本大和、平野真希子、井口智弘、青木和正、村松正明、正井久雄、宮武昌一郎
    • Organizer
      分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-26460585
  • [Presentation] GATA3 and inflammatory disease2015

    • Author(s)
      Shoichiro Miyatake
    • Organizer
      International Symposium on Immune Regulation
    • Place of Presentation
      Oharai Park Hotel, Oharai, Ibaraki
    • Year and Date
      2015-10-29
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460585
  • [Presentation] Dermatitis development in GATA3 defective mice2015

    • Author(s)
      Shoichiro Miyatake, Kazuhisa Aoki, Tomohiro Iguchi
    • Organizer
      The 44th Annual Meeting of the Japanese Society of Immunology
    • Place of Presentation
      Sapporo Convention Center, Sapporo, Hokkaido
    • Year and Date
      2015-11-17
    • Data Source
      KAKENHI-PROJECT-26460585
  • [Presentation] T細胞の増殖制御に必須な新規BTB-ZFタンパク質ZNF131 (Zbtb35)2015

    • Author(s)
      宮武 昌一郎, 青木 和久, 正井 久雄, 井口 智弘
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場、神戸、兵庫
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460585
  • [Presentation] BTB-ZF transcription factor ZNF131 is crucial for early T cell development in thymus and exerts its function through the interaction with GATA3 KTCC 20132013

    • Author(s)
      Miyatake S
    • Organizer
      Sixth International Workshop of Kyoto T Cell Conference 2013 (招待講演)
    • Place of Presentation
      Kyoto University Shiran Kaikan, Kyoto
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] BTB-ZF transcription factor ZNF131 is crucial for early T cell development in thymus and exerts its function through the interaction with GATA32013

    • Author(s)
      Miyatake S
    • Organizer
      KTCC 2013: Sixth International Workshop of Kyoto T Cell Conference
    • Place of Presentation
      Kyoto University Shiran Kaikan
    • Invited
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] The role of POZ-ZF protein Znf131 in T cell homeostasis2012

    • Author(s)
      Iguchi T (Miyatake S)
    • Organizer
      Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Kobe International Conference Center, Kobe
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] POZ-ZF protein, ZNF131 is required for the development of T cells during the double negative stage as well as for the maintenance in the periphery Gene Expression & Signaling in the Immune System2012

    • Author(s)
      Iguchi T, Aoki K, Taya C, Sakimura K, and Miyatake S
    • Organizer
      Cold Spring Harbor Meeting
    • Place of Presentation
      Cold Spring Harbor Institute, New York, USA
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] T細胞の分化に関与するDNA脱メチル化酵素の探索2012

    • Author(s)
      青木和久、宮武昌一郎
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場、福岡
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] The role of POZ-ZF protein Znf131 in T cell homeostasis Annual Meeting of the Japanese Society for Immunology2012

    • Author(s)
      Iguchi T, Aoki K, Aihara Y and Miyatake S
    • Place of Presentation
      Kobe International Conference Center, Kobe
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] POZ-ZF protein, ZNF131 is required for the development of T cells during the double negative stage as well as for the maintenance in the periphery2012

    • Author(s)
      Iguchi T(Miyatake S)
    • Organizer
      Gene Expression & Signaling in the Immune System (Cold Spring Harbor Meeting)
    • Place of Presentation
      Cold Spring Harbor Institute, New York, USA
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] T 細胞恒常性維持におけるZNF131 の役割2012

    • Author(s)
      井口智弘、青木和久、相原祐子、宮武昌一郎
    • Organizer
      第22回 Kyoto T Cell Conference(KTCC)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] T細胞恒常性維持におけるZNF131の役割2012

    • Author(s)
      井口 智弘(宮武 昌一郎)
    • Organizer
      第22回 Kyoto T Cell Conference (KTCC)
    • Place of Presentation
      和順会館、京都
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] POZ-ZFタンパク質であるZNF131のT細胞分化およびホメオスタシスにおける役割2011

    • Author(s)
      井口智弘、宮武昌一郎
    • Organizer
      日本免疫学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] T 細胞分化および活性化における、BTB/POZ ドメインとZn フィンガーを持つ遺伝子2011

    • Author(s)
      井口智弘、宮武昌一郎
    • Organizer
      ZNF131 の機能解明KTCC(Kyoto T Cell Conference)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] T細胞分化および活性化における、BTB/POZドメインとZnフィンガーを持つ遺伝子、ZNF131の機能解明2011

    • Author(s)
      井口智弘、宮武昌一郎
    • Organizer
      KTCC (Kyoto T Cell Conference)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] Epigenetic regulation in T cell development Annual Meeting of the Molecular Biology Society of Japan2011

    • Author(s)
      Kazuhisa Aoki, Shoichiro Miyatake
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] POZ-ZF タンパク質であるZNF131 のT 細胞分化およびホメオスタシスにおける役割2011

    • Author(s)
      井口智弘、宮武昌一郎
    • Organizer
      日本免疫学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] Epigenetic regulation in T cell development2011

    • Author(s)
      Kazuhisa Aoki, Shoichiro Miyatake
    • Organizer
      Annual Meeting of the Molecular Biology Society of Japan
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] GATA3 結合分子群の解析KTCC2010

    • Author(s)
      宮武昌一郎、青木和久、田沼雄一、村越早絵、井口智弘
    • Organizer
      Kyoto T cell Conference
    • Place of Presentation
      京都大学芝蘭会館、京都
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] Il4 Intronic enhancer HS2 is critical element regulating the GATA-3 mediated type 2 helper T cell development.2010

    • Author(s)
      Kubo, M., Motomura, Y., Tanaka S., Suzuki, Y., Inoue, H., Miyatake, S.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      Kobe Portopia Hotel/Kobe International Exhibition Hall, Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] T 細胞分化に伴うサイトカイン産生のエピジェネティック制御2010

    • Author(s)
      青木和久、宮武昌一郎
    • Organizer
      第33回日本分子生物学会, 第83回日本生化学会 合同大会
    • Place of Presentation
      神戸ポートピアホテル/神戸国際展示場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] Function of Bst2/tetherin in immune response.2010

    • Author(s)
      Iguchi, T., Yoshitani, H., Aoki, K., Miyatake, S.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      Kobe Portopia Hotel/Kobe International Exhibition Hall, Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] Function of Bst2/tetherin in immune response2010

    • Author(s)
      Iguchi, T. Yoshitani, H. Aoki, K. Miyatake, S
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe Portopia Hotel/Kobe International Exhibition Hall, Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] GATA3結合分子群の解析2010

    • Author(s)
      宮武昌一郎、青木和久、田沼雄一、村越早絵、井口智弘
    • Organizer
      KTCC(Kyoto T cell Conference)
    • Place of Presentation
      京都大学芝蘭会館(京都府)
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] T細胞分化に伴うサイトカイン産生のエピジェネティック制御2010

    • Author(s)
      青木和久、宮武昌一郎
    • Organizer
      第33回日本分子生物学会 第83回日本生化学会合同大会
    • Place of Presentation
      神戸ポートピアホテル/神戸国際展示場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] Il4 Intronic enhancer HS2 is critical element regulating the GATA-3 mediated type 2 helper T cell development2010

    • Author(s)
      Kubo, M., Motomura, Y., Tanaka, S. Suzuki, Y. Inoue, H., Miyatake, S
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe Portopia Hotel/Kobe International Exhibition Hall, Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-22590279
  • [Presentation] 胸腺と末梢のCD4陽性T細胞におけるサイトカイン発現パターンの差異はDNA脱メチル化制御の差異による2008

    • Author(s)
      青木和久、宮武昌一郎
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] T細胞サイトカイン産生における脱メチル化制御の役割2008

    • Author(s)
      青木和久, 宮武昌一郎
    • Organizer
      第18回 kyoto T cell Conference
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] T細胞サイトカイン産生における脱メチル化制御の役割2008

    • Author(s)
      宮武昌一郎、青木和久
    • Organizer
      第18回kyoto T cell Conference
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] Different cytokine expression and DNA demethylation profiles between CD4 single positive thymocytes and peripheral naive T cells.2008

    • Author(s)
      Aoki, K. and Miyatake, S.
    • Organizer
      The 38th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] C-terminal transactivation domain is required for NFAT-mediated TNF-alpha synthesis by T cells.2008

    • Author(s)
      Kaminuma, O., Kitamura, F., Kitamura, N., Miyatake, S., Hiroi, T.
    • Organizer
      The 38th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] Different cytokine expression and DNA demethylation profiles between CD4 single positive thymocytes and peripheral naive T cells2008

    • Author(s)
      青木和久, 宮武昌一郎
    • Organizer
      The 38th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] Th2サイトカイン遺伝子領域における複製開始点および複製タイミングの解析2007

    • Author(s)
      宮武 昌一郎、青木 和久、正井 久雄
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18058024
  • [Presentation] Th2サイトカイン遺伝子領域における複製開始点および複製タイミングの解析2007

    • Author(s)
      宮武昌一郎、青木和久、正井久雄
    • Organizer
      第30回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] アレルギー学の基礎2007

    • Author(s)
      宮武昌一郎
    • Organizer
      第31回専門医教育セミナープログラム 日本アレルギー学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-06-12
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] Analysis of DNA demethylation coupled with CD4+ T cell subset differentiation2007

    • Author(s)
      Aoki, K. and Miyatake, S.
    • Organizer
      The 37th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] サイトカイン遺伝子領域における複製開始点および複製タイミングの解析2007

    • Author(s)
      宮武昌一郎、尾田真子、佐藤憲子、青木和久、正井久雄
    • Organizer
      特定領域研究「染色体サイクルの制御ネットワーク」第3回領域会議
    • Place of Presentation
      石川県加賀
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] Analysis of DNA demethylation coupled with CD4+T cell subset differentiation2007

    • Author(s)
      Aoki, K. and Miyatake, S.
    • Organizer
      The 37thAnnual Meeting of the Japanese Society for lmmunology
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-18058024
  • [Presentation] Analysis of DNA demethylation coupled with CD4+Tcell subset differentiation2007

    • Author(s)
      Aoki, K..and Miyatake, S.
    • Organizer
      The 37th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] T細胞の分化に伴うDNAの脱メチル化による遺伝子発現制御2007

    • Author(s)
      青木和久、宮武昌一郎
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590296
  • [Presentation] Interaction of Gata3 and ZNF131 in hematopoiesis

    • Author(s)
      Tomohiro Iguchi, Shoichiro Miyatake
    • Organizer
      KTCC
    • Place of Presentation
      京都平安ホテル、京都
    • Year and Date
      2014-05-16 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-26460585
  • [Presentation] GATA3, old timer and ZNF131, newcomer in T cell development and function

    • Author(s)
      Shoichiro Miyatake
    • Organizer
      The 2014 Fall Conference of the Korean Association of Immunologists
    • Place of Presentation
      Sejong University Convention Center, Seoul, Korea
    • Year and Date
      2014-11-06 – 2014-11-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460585
  • [Presentation] Role of POZ-ZF protein, ZNF131 in hematopoietic cell proliferation and differentiation

    • Author(s)
      Tomohiro Iguchi, Shoichiro Miyatake
    • Organizer
      The 43rd Annual Meeting of The Japanese Society of Immunology
    • Place of Presentation
      Kyoto International Conference Center, Kyoto
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-26460585
  • 1.  SAITO Takashi (50205655)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  AOKI Kazuhisa (00280785)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 32 results
  • 3.  SATO Noriko (70280956)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 4.  MASAI Hisao (40229349)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 5.  SHINMOTO Micie (20216237)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  ARASE Hisashi (10261900)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  YOSHIZAWA Naoko (30344071)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  TAKAI Yuko (90332270)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  MATSUMOTO Seiji (40190532)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  MORIYAMA Kenji (00250217)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  OHNO Hiroshi (50233226)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  ISHII Ai (80124436)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TANAKA Taku (80425686)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KANO Yutaka (90450593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ODA Masako (50399474)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ITO Sayuri (60462777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HAYANO Motoshi (30593644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KAKUSHO Naoko (30599593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ARAI Ken-ichi (00012782)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  WATANABE Sumiko (60240735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  HATANO Osamu (40164850)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  MIYATAKE Yoshiko (10267213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 23.  NEJIMA Jyun (00164658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  村上 洋太 (20260622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  伊藤 嘉明 (80004612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  林田 敏朗 (20342925)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  神沼 修 (80342921)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 28.  山口 敦美 (70124500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KAMOGAWA Yumiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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