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MAJIMA Tokifumi  眞島 任史

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… Alternative Names

真島 任史  マジマ トキフミ

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Researcher Number 30241334
Other IDs
External Links
Affiliation (Current) 2025: 東京国際大学, 医療健康学部, 教授
Affiliation (based on the past Project Information) *help 2007 – 2011: Hokkaido University, 大学院・医学研究科, 特任教授
2006: 北海道大学, 大学院医学研究科, 助教授
2003 – 2005: Hokkaido Univ., Grad.School of Medicine, Asso.Prof., 大学院・医学研究科, 助教授
2002: 北海道大学, 大学院・医学研究科, 助手
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Biomedical engineering/Biological material science
Except Principal Investigator
Orthopaedic surgery / Orthopaedic surgery
Keywords
Principal Investigator
RGD / リモデリング / Extra cellular matrix / Alginate / Hyaluronan / Chitosan / Ligament / Joint cartilage / Tissue engineering / 靱帯 … More / 細胞外マトリックス / アルギンサン / ヒアルロンサン / キトサン / 靭帯 / 関節軟骨 / 運動器再生 / 繊維芽細胞 / 線維芽細胞 / 腱・靭帯 / バイオメカニクス / siRNA / 遺伝子解析 / 変形性関節症 / MMP13 / 力学的負荷 / 腱 / オステオポンチン … More
Except Principal Investigator
細胞接着因子 / Extracellular matrix / Fibroblasts / Remodeling / Collagen / Ligament reconstruction / Mechanical properties / Ligament / Tendon / 細胞外マトリクス / 線維芽細胞 / リモデリング / 自家腱移植 / 膝蓋腱 / 細胞外マトリックス / 繊維芽細胞 / 再構築現象 / コラゲン / 靭帯再建術 / 力学特性 / 靭帯 / 腱 / 神経成長因子 / キトサン / チューブ / 神経再生 / 糖鎖 / scaffold / 成長因子 / 組織再生 / 神経 Less
  • Research Projects

    (7 results)
  • Research Products

    (40 results)
  • Co-Researchers

    (11 People)
  •  Effect of mechanical stress to ligament/tendon fibroblast under 3D culture environmentPrincipal Investigator

    • Principal Investigator
      MAJIMA Tokifumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Hokkaido University
  •  Analysis of gene expression in osteoarthritis initiation andthe applicability to the treatmentPrincipal Investigator

    • Principal Investigator
      MAJIMA Tokifumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Hokkaido University
  •  神経組織再生のための新規多機能生体内吸収性基材の開発

    • Principal Investigator
      三浪 明男
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Hokkaido University
  •  腱・靭帯のリモデリングにおけるオステオポンチンの効果の解明と治療への応用Principal Investigator

    • Principal Investigator
      真島 任史 (眞島 任史)
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Hokkaido University
  •  神経組織再生のための新規多機能生体内吸収性基材の開発

    • Principal Investigator
      MINAMI Akio
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Hokkaido University
  •  Detailed molecular design of artificial extra cellular matrix and application for ligament and cartilage tissue engineeringPrincipal Investigator

    • Principal Investigator
      MAJIMA Tokifumi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  THE ROLE OF EXTRINSIC INFROBLASTS IN THE RTEMODELING OF THE PATELLAR TENDON MATRIX

    • Principal Investigator
      TOHYAMA Harukazu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      HOKKAIDO UNIVERSITY

All 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book

  • [Book] The knee A comprehensisve Review, Osteotomies about the knee. Chapter 122010

    • Author(s)
      Majima T
    • Total Pages
      594
    • Publisher
      World Scientific, New Jersey, USA
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Book] Chapter 12, Osteotomies about the knee

    • Author(s)
      Majima T
    • Publisher
      New Jersey, USA
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Journal Article] MEffect of Japanese herbal medicine, Boiogito, on osteoarthritic knee with joint effusion2012

    • Author(s)
      Majima T, Inoue M, et. al
    • Journal Title

      Sports Med, Arthroscopy, Rehabilitation, Therapy & Technology

      Volume: 4 Issue: 1 Pages: 3-3

    • DOI

      10.1186/1758-2555-4-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Journal Article] Patella eversion deteriorates early knee functional recovery after TKA -Comparison between MIS TKA and conventional TKA-2011

    • Author(s)
      Majima T, Nishiike O, et. al
    • Journal Title

      Arthritis

      Volume: 2011 Pages: 1-6

    • DOI

      10.1155/2011/854651

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Journal Article] A biomechanical and histological evaluation of a tissue engineered ligament using chitosan and hyaluronan hybrid polymer fibers : A rabbit medial collateral ligament reconstruction model2011

    • Author(s)
      Irie T, , Majima T, et. al
    • Journal Title

      J Biomed Mat Res A

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Journal Article] キトサン・ヒアルロンサ酸ハイブリッド繊維を用いた組織工学的手法による靭帯再生2011

    • Author(s)
      真島任史
    • Journal Title

      整形外科

      Volume: 62 Pages: 1-088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Journal Article] キトサン・ヒアルロンサ酸ハイブリッド繊維を用いた組織工学的手法による靱帯再生2011

    • Author(s)
      眞島任史
    • Journal Title

      整形外科

      Volume: 62 Pages: 1088-1088

    • Data Source
      KAKENHI-PROJECT-21500399
  • [Journal Article] Effect of cyclic 3D strain on cell proliferation and collagen synthesis of fibroblast seeded chitosan-hyalronan hybrid polymer fiber2010

    • Author(s)
      Sawaguchi N, Majima T, et. Al
    • Journal Title

      J Orthop Sci

      Volume: 15 Pages: 569-577

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Journal Article] Down-regulation of cathepsin K insynovium leads to progression ofosteoarthritis in rabbits2009

    • Author(s)
      Takahashi D., Iwasaki N., Kon S.,Matsui Y., Majima T., Minami A. Uede T.
    • Journal Title

      Arthritis & Rheumatism, (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591745
  • [Journal Article] Chitosan-based hyaluronan hybrid polymer fibre scaffold for ligamant and tendon tissue engineering2007

    • Author(s)
      Majima, T., Irie, T., Sawaguchi, N., Funakoshi, T., Iwasaki, N., Harada, K., Minami, A., and Nishimuara, SI
    • Journal Title

      J Engineering in Med 221

      Pages: 537-546

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659431
  • [Journal Article] Effect of pore size on in vitro cartilage formation using chitosan-based hyaluronic acid hybrid polymer fibers2007

    • Author(s)
      Yamane, S., Iwasaki, N., Kasahara, Y., Harada, K., Majima, T., Monde, K., Nishimura, S. I., and Minami, A.
    • Journal Title

      J Biomed Mater Res A 81

      Pages: 586-593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659431
  • [Journal Article] The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation.2007

    • Author(s)
      Mori N, Majima T, et al.
    • Journal Title

      Matrix Biology Jan;26(1)

      Pages: 42-53

    • NAID

      120000961947

    • Data Source
      KAKENHI-PROJECT-17659457
  • [Journal Article] 腱・靭帯再生に用いるバイオリアクターの開発2005

    • Author(s)
      沢口直弘, 眞島任史
    • Journal Title

      日本臨床バイオメカニクス学会誌 26

      Pages: 27-33

    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Chitosan-RGDSGGC-conjugate as a scaffold material for musculoskeletal tissue engineering.2005

    • Author(s)
      Masuko T, Iwasaki N, Majima T, Yamane S, Funakoshi T, Minami A, Ohsuga N, Ohta T, Nishimura S
    • Journal Title

      Biomaterials (In press)

    • Data Source
      KAKENHI-PROJECT-15659345
  • [Journal Article] An efficient method for the conjugation of chitosan with cell adhesive peptides : controlling cell adhesion and proliferation activities in musculoskeletal tissue engineering by chitosan-RGDSGGC-conjugate as a novel scaffold material.2005

    • Author(s)
      Masuko T, Iwasaki N, Yamane S, Funakoshi T, Majima T, Minami A, Ohsuga N, Ohta T, Nishimura S
    • Journal Title

      Biomaterials 26

      Pages: 5339-5347

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Thiolation of chitosan. Attachment of proteins via thioether formation.2005

    • Author(s)
      Masuko T, Minami A, Iwasaki N, Majima T, et al.
    • Journal Title

      Biomacromolecules (In press)

    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] 腱・靱帯再生に用いるバイオリアクターの開発2005

    • Author(s)
      沢口直弘, 眞島任史
    • Journal Title

      日本臨床バイオメカニクス学会誌 26

      Pages: 27-33

    • NAID

      10017097064

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Application of tissue engineering techniques for rotator cuff regeneration using a chitosan-based hyaluronan hybrid fiber scaffold2005

    • Author(s)
      Funakoshi T, Majima T, Iwasaki N, Yamane S, Masuko T, Minami A, Harada K, Nishimura S
    • Journal Title

      Am J Sports Med 33

      Pages: 1193-1201

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] An efficient method for the conjugation of chitosanwith cell Adhesive peptides : controlling cell adhesion and proliferation activities in musculoskeletal tissue engineering by chitosan-RGDSGGC-conjugate as a novel scaffold material.2005

    • Author(s)
      Masuko T, Iwasaki N, Yamane S, Funakoshi T, Majima T, Minami A, Ohsuga N, Ohta T, Nishimura S
    • Journal Title

      Biomaterials 26

      Pages: 5339-5347

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Alginate and chitosan polyion complex fibers for scaffold in ligament tissue engineering.2005

    • Author(s)
      Majima T, Funakoshi T, Iwasaki N, et al.
    • Journal Title

      J Orthop Science (In press)

    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Novel chitosan based hyaluronan hybrid polymer fiber for a scaffold in ligament tissue engineering.2005

    • Author(s)
      Funakoshi T, Majima T, Iwasaki N, et al.
    • Journal Title

      J Biomed Material Res (In press)

    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Novel chitosan based hyaluronan hybrid polymer fiber for a scaffold in ligament tissue engineering.2005

    • Author(s)
      Funakoshi T, Majima T, Iwasaki N, et al.
    • Journal Title

      J Biomed Material Res 74

      Pages: 338-346

    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Novel chitosan based hyaluronan hybrid Polymer fiber for a scaffold in ligament tissue engineering.2005

    • Author(s)
      Funakoshi T, Majima T, Iwasaki N, Yamane S, Masuko T, Minami A, Harada K, Nishimura S
    • Journal Title

      J Biomed Material Res 74

      Pages: 338-346

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Application of tissue engineering techniques for rotator cuff regeneration using a chitosan-based hyaluronan hybrid fiber scaffold.2005

    • Author(s)
      Funakoshi T, Majima T, Iwasaki N, Yamane S, Masuko T, Minami A, Harada K, Nishimura S
    • Journal Title

      Am J Sports Med 33

      Pages: 1193-1201

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Feasibility of chitosan-based hyaluronic acid hybrid biomaterial for a novel scaffold in cartilage tissue engineering.2005

    • Author(s)
      Yamane S, Iwasaki N, Majima T, et al.
    • Journal Title

      Biomaterials 26

      Pages: 611-619

    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Alginate and chitosan polyion complex fibers for scaffold in ligament tissue engineering.2005

    • Author(s)
      Majima T, Funakoshi T, Iwasaki N, Yamane S, Minami A, Harada N, Nonaka S, Maekawa N, Tamura Y, Tokura S, Monde K, Nishimura S
    • Journal Title

      J Orthop Sci 10

      Pages: 302-307

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Novel chitosan based hyaluronan hybrid polymer fiber for a scaffold in ligament tissue engineering.2005

    • Author(s)
      Funakoshi T, Majima T, Iwasaki N, Yamane S, Masuko T, Minami A, Harada K, Nishimura S
    • Journal Title

      J Biomed Material Res 74

      Pages: 338-346

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] New bioreactor system for ligament and tendon tissue engineering.2005

    • Author(s)
      Sawaguchi N, Majima T
    • Journal Title

      J Japan Sci Clin Biomecha Res 26

      Pages: 27-33

    • NAID

      10017097064

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Feasibility of chitosan-based hyaluronic acid Hybrid biomaterial for a novel scaffold in cartilage tissue engineering2005

    • Author(s)
      Yamane S, Iwasaki N, Majima T, Funakoshi T, Masuko T, Harada K, Minami A, Monde K, Nishimura S
    • Journal Title

      Biomaterials 26

      Pages: 611-619

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Alginate and chitosan polyion complex fibers for scaffold in ligament tissue engineering.2005

    • Author(s)
      Majima T, Funakoshi T, Iwasaki N, Yamane S, Minami A, Harada N, Nonaka S, Maekawa N, Tamura Y, Tokura S, Monde K, Nishimaura S
    • Journal Title

      J Orthop Sci 10

      Pages: 302-307

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Feasibility of chitosan-based hyaluronic acid hybrid biomaterial for a novel scaffold in cartilage tissue engineering.2005

    • Author(s)
      Yamane S, Iwasaki N, Majima T, Funakoshi T, Masuko T, Harada K, Minami A, Monde K, Nishimura S
    • Journal Title

      Biomaterials 26

      Pages: 611-619

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390447
  • [Journal Article] Thiolation of chitosan. Attachment of proteins via thioether formation.2005

    • Author(s)
      Masuko T, Minami A, Iwasaki N, Majima T, Nishimura S, Lee YC
    • Journal Title

      Biomacromolecules (In press)

    • Data Source
      KAKENHI-PROJECT-15659345
  • [Presentation] Chitosan-based Hyaluronan Hybrid Polymer Fiber Scaffold for Liga ment/Tendon Tissue Engineering2011

    • Author(s)
      Majima T
    • Organizer
      The 5th International Cell Therapy Conference
    • Place of Presentation
      Seoul National University Hospital, Seoul
    • Year and Date
      2011-11-01
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Presentation] Chitosan-based Hyaluronan Hybrid Polymer Fiber Scaffold for Ligament/Tendon Tissue Engineering2011

    • Author(s)
      Majima T
    • Organizer
      The 5th International Cell Therapy Conference
    • Place of Presentation
      Seoul National University Hospital, Seoul(招待講演)
    • Year and Date
      2011-11-01
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Presentation] キトサン・ヒアルロン酸ハイブリット繊維を用いた組織工学的手法による靭帯再生2010

    • Author(s)
      眞島任史
    • Organizer
      日本整形外科基礎学会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21500399
  • [Presentation] Down- regulation of cathepsin K insynovium accelerates cartilage degradationin rabbits2008

    • Author(s)
      Takahashi D., Iwasaki N., Matsui Y.,Matsuhashi T., Asano T., Majima T.,Minami A., Kimura C., Kon S., Uede T.
    • Organizer
      54th Annual Meeting of the OrthopaedicResearch Society
    • Place of Presentation
      MosconeWest Convention Center, (San FransiscoCA, USA)
    • Year and Date
      2008-03-02
    • Data Source
      KAKENHI-PROJECT-19591745
  • [Presentation] 関節滑膜で発現するカテプシンKは軟骨変性を抑制す2008

    • Author(s)
      高橋大介, 岩崎倫政 松井雄一郎, 眞島任史, 三浪明男, 上出利光
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      アクトシティ浜松(浜松市)
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-19591745
  • [Presentation] 関節滑膜で発現するカテプシンKは軟骨変性を抑制する2008

    • Author(s)
      高橋大介, 岩崎倫政, 松井雄一郎, 松橋智弥, 浅野毅, 眞島任史, 三浪明男, 上出利光
    • Organizer
      第21回日本軟骨代謝学会
    • Place of Presentation
      京都テルサ(京都市)
    • Year and Date
      2008-03-21
    • Data Source
      KAKENHI-PROJECT-19591745
  • [Presentation] 関節滑膜内のカテプシンKはMMP-13の発現を抑制する2008

    • Author(s)
      高橋大介, 岩崎倫政, 松井雄一郎, 浅野毅, 眞島任史, 三浪明男, 今重之, 上出利光
    • Organizer
      第23回日本整形外科学会基礎学術集会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-19591745
  • [Presentation] 腱・靭帯損傷に対する再生医療-キトサンーヒアルロン酸ハイブリッド繊維Scaffoldの有効性-2007

    • Author(s)
      眞島任史、岩崎倫政、船越忠直、入江徹、沢口直弘、原田和夫、三浪明男、西村紳一郎
    • Organizer
      第80回日本整形外科学会学術総会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Year and Date
      2007-05-26
    • Data Source
      KAKENHI-PROJECT-18659431
  • 1.  MINAMI Akio (20133738)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 16 results
  • 2.  IWASAKI Norimasa (30322803)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 20 results
  • 3.  NISHIMURA Shin-ichiro (00183898)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 4.  SAWAGUCHI Naohiro (80435982)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  KASAHARA Yasuhiko (00581927)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TOHYAMA Harukazu (60301884)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  NISHIHIRA Jun (30189302)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YASUDA Kazunori (20166507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MONDE Kenji (40210207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 10.  今 重之 (90344499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  井上 正弘 (40374376)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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