ISHIHARA Hirokazu 石原裕和

… Alternative Names

石原裕和イシハラヒロカズ

ISHIHARA H 石原裕和

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Researcher Number	30242499
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005: TOYAMA UNIVERSITY, UNIVERSITY HOSPITAL, ASSISTANT PROFESSOR, 附属病院, 講師 2002 – 2004: Toyama Medical and Pharmaceutical University, University Hospital, Assistant Professor, 附属病院, 講師 2003: 富山医科薬科大学, 医学部附属病院, 講師 2001: 富山医科薬科大学, 医学部附属病院, 講師 2000: 富山医科薬科大学, 附属病院, 講師 … More 1997 – 1998: 富山医科薬科大学, 医学部, 助手 1996: 富山医科薬科大学, 附属病院, 助手 1993 – 1994: 富山医科薬科大学, 付属病院, 助手 1993 – 1994: 富山医科薬科大学, 附属病院・整形外科, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery
Keywords	Principal Investigator プロテオグリカン / 椎間板代謝 / 静水圧 / 抑制物質(TIMP) / 金属性蛋白分解酵素(MMP-3) / i-NOS / NO(Nitric Oxide) / TUMOR NECROTIZING FACTOR / MATRIX METALLOPROTEINASE / NITRIC OXIDE (NO) … More / INTERVERETBRAL DISC DGENERATION / Tumor necrotizing factor(TNF)-α / Tumor necrotizing Factor(TNF)-α / Tumor necrotizing factor-α / Matrix metalloproteinase(MMP) / Nitric Oxide(NO) / 椎間板変性 / Intervertebral disc metabolism / Proteoglycan / Nitric Oxide / プロオテオグリカン / NO (Nitric Oxide) / アンチセンスオリゴヌクレオチド / I-Nos / 椎体間代謝 / プロテオグリガン / NO(Nitric oxide) … More Except Principal Investigator PCR / 腰椎椎間板ヘルニア / IX collagen gene / Aggrecan gene / Vitamin-D receptor gene / Case-control study / Genetic polymorphism / Lumbar disc disease / Lumbar disc herniation / TGF-β1遺伝子 / エストロゲンレセプター遺伝子 / 制限酵素 / ハプロタイプ / MMP-3 / COL9A3 / COL9A2 / 遺伝子 / 遺伝的素因 / 腰椎椎間板変性 / 患者-対照相関解析 / PCR法 / IX型コラーゲン遺伝子 / アグリカン遺伝子 / ビタミンDレセプター遺伝子 / 患者-対象相関解析 / 疾患関連遺伝子 / 腰椎椎間板疾患 / Immunohistochemistry / Immunology / Intervertebral disc / Monoclonal antibody / 免疫組織化学 / 免疫機構 / 椎間板変性 / モノクローナル抗体 / 遺伝子治療 / cilp / adamts-5 / adamts-4 / siRNA / 三次元培養 / 軟骨 / 椎間板 / 腰椎間板ヘルニア / low back pain / lumbar disc disease / interverbral disc / gene therapy / RNAi / adamts-4, 5 / adamts-4,5 / si RNA / 椎間板内治療 Less

Effect of small interference RNA(siRNA)for ADAMTS5 on intervertebral disc degeneration
- Principal Investigator
  
  YOSHIHARU Kawaguchi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Toyama
THE ROLE OF NITRIC OXIDE, MATRIX METALLOPTOTEINASE AND TUMOR NECROTIZING FACTOR-α DURING THE PROCESS OF INTERVERTEBRAL DISC DEGENERATION AND REGENERATIONPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hirokazu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA UNIVERSITY, UNIVERSITY HOSPITAL
  Toyama Medical and Pharmaceutical University
Analysis of causative gene for lumbar disc disease and investigation of molecular mechanism for interverteral disc degeneration
- Principal Investigator
  
  KAWAGUCHI Yoshiharu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
THE ROLE OF NITRIC OXIDE DURING THE PROCESS OF INTERVERTEBRAL DISC DEGENERATION AND PREVENTION OF DISC DEGENERATION USING i-NOS ANTI SENSE OLIGONUCLEOTIDEPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hirokazu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
椎間板変性の実相解明、とくに静水圧環境変化に伴う椎間板NO産生と基質合成Principal Investigator
- Principal Investigator
  
  石原裕和
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
ヒト椎間板マトリックスメタロプロテアーゼの産生調節機構と椎間板変性機序と制御Principal Investigator
- Principal Investigator
  
  石原裕和
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
静水圧の椎間板基質分解酵素産生に及ぼす影響とその調節機構Principal Investigator
- Principal Investigator
  
  石原裕和
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
振動静水圧環境におけるヒト椎間板の性、年齢区画別基質合成、解離の特性Principal Investigator
- Principal Investigator
  
  石原裕和
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
Immunological effect of CB-11mAb on intervertebral disc degeneration
- Principal Investigator
  
  TSUJI Haruo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

All 2005 2004 2003

All Journal Article Book

[Book] The Lumbar Spine, 3 rd Edition.(CHAPTER 59)2004
- Author(s)
  Ishihara H.
- Publisher
  Lippincott Williams & Wilkins, Philadelphia
- Data Source
  KAKENHI-PROJECT-15591569
[Book] The Lumbar Spine, 3 rd Edition. (CHAPTER 59)2004
- Author(s)
  Ishihara H.
- Publisher
  Lippincott Williams & Wilkins, Philadelphia
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] H-shaped autologous bone graft associated with a ceramic interspinous block for the posterior lumbar fusion.2005
- Author(s)
  Kanamori M, Ishihara H, Yasuda T, et al.
- Journal Title
  
  J Lumbar Spine Disord 11
  
  Pages: 157-163
- NAID
  130000136066
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Spinal stenosis due to ossified lumbar lesions2005
- Author(s)
  Kawaguch Y, Kanamori M, Ishihara H, et al.
- Journal Title
  
  J Neurosurg Spine 2
  
  Pages: 262-270
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Calcium phosphate cement leakage after percutaneous vertebroplasty for osteoporotic vertebral fractures.2005
- Author(s)
  Nakano M, Hirano N, Ishihara H, et al.
- Journal Title
  
  J Neurosurg Spine 2
  
  Pages: 27-33
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Calcium phosphate cement leakage after percutaneous rertebroplasty for osteoporotic vertebral fractures.2005
- Author(s)
  Nakano M, Hirano N, Ishihara H, et al.
- Journal Title
  
  J Neurosurg Spine 2
  
  Pages: 27-33
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Calcium phosphate cement leakage after percutaneous vertebroplasty for osteoporotic vertebral fractures.2005
- Author(s)
  Nakano M, Ishihara H, Kawaguchi Y, et al.
- Journal Title
  
  J Neurosurg(Spine) 2
  
  Pages: 27-33
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] 腰椎椎間板疾患の素因に関わる遺伝子解析. シンポジウム2004
- Author(s)
  川口善治, 関庄二, 阿部由美子, 金森昌彦, 石原裕和, 信清正典, 杉森一仁, 木村友厚
- Journal Title
  
  椎間板変性の分子メカニズムから治療. 日整会誌 78
  
  Pages: 918-922
- Data Source
  KAKENHI-PROJECT-17591556
[Journal Article] CHAPTER 59, Degenerative Lumbar Spinal Stenosis with Scoliosis-Kyphosis : Surgical Techniques, Results and Complications.2004
- Author(s)
  Ishihara H, Matsui H.
- Journal Title
  
  The Lumbar Spine, 3 rd Edition. (Edited by Herkowits H, Dvorak J, Bell G, Nordin M, Grob D.)(Lippincott Williams & Wilkins, Philadelphia)
  
  Pages: 547-555
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Adjacent segment disease following anterior cervical interbodyfusion.2004
- Author(s)
  Ishihara H, Kanamori M, Kawaguchi Y et al.
- Journal Title
  
  The Spine J 4
  
  Pages: 624-628
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Adjacent segment disease following anterior cervical interbody fusion.2004
- Author(s)
  Ishihara H, Kanamori M, Kawaguchi Y et al.
- Journal Title
  
  The Spine J 4
  
  Pages: 624-628
- NAID
  10009771840
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Clinical and radiographic results of expansive lumbar laminoplasty in patients with spinal stenosis.2004
- Author(s)
  Kawaguchi Y, Kanamori M, Ishihara H, et al.
- Journal Title
  
  J Bone Joint Surg 86-A
  
  Pages: 1698-1703
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Upper thoracic myelopathy caused by vertebral collapse and subluxation in rheumatoid arthritis.2004
- Author(s)
  Nakamura C, Kawaguchi Y, Ishihara H, et al.
- Journal Title
  
  J Orthop Sci 9
  
  Pages: 629-634
- Data Source
  KAKENHI-PROJECT-15591569
[Journal Article] Characteristics of nerve root compression caused by degenerative lumbar spinal stenosis with scoliosis.2003
- Author(s)
  Liu H, Ishihara H, Kanamori M, Kawaguchi Y, et al.
- Journal Title
  
  The Spine J 3
  
  Pages: 524-529
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591569

1. YOSHIHARU Kawaguchi (00262527)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. OSADA Ryusuke (40293310)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TSUJI Haruo (90009449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MATSUNO H (00219461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SEKI Shoji

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

ISHIHARA Hirokazu 石原 裕和

石原 裕和 イシハラ ヒロカズ

ISHIHARA H 石原 裕和

Research Projects

Research Products

Co-Researchers

Effect of small interference RNA(siRNA)for ADAMTS5 on intervertebral disc degeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE ROLE OF NITRIC OXIDE, MATRIX METALLOPTOTEINASE AND TUMOR NECROTIZING FACTOR-α DURING THE PROCESS OF INTERVERTEBRAL DISC DEGENERATION AND REGENERATIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of causative gene for lumbar disc disease and investigation of molecular mechanism for interverteral disc degeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE ROLE OF NITRIC OXIDE DURING THE PROCESS OF INTERVERTEBRAL DISC DEGENERATION AND PREVENTION OF DISC DEGENERATION USING i-NOS ANTI SENSE OLIGONUCLEOTIDEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

椎間板変性の実相解明、とくに静水圧環境変化に伴う椎間板NO産生と基質合成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト椎間板マトリックスメタロプロテアーゼの産生調節機構と椎間板変性機序と制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

静水圧の椎間板基質分解酵素産生に及ぼす影響とその調節機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

振動静水圧環境におけるヒト椎間板の性、年齢区画別基質合成、解離の特性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological effect of CB-11mAb on intervertebral disc degeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] The Lumbar Spine, 3 rd Edition.(CHAPTER 59)2004

Author(s)

Publisher

Data Source

[Book] The Lumbar Spine, 3 rd Edition. (CHAPTER 59)2004

Author(s)

Publisher

Description

Data Source

[Journal Article] H-shaped autologous bone graft associated with a ceramic interspinous block for the posterior lumbar fusion.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Spinal stenosis due to ossified lumbar lesions2005

Author(s)

Journal Title

Description

Data Source

ISHIHARA Hirokazu 石原裕和

石原裕和イシハラヒロカズ

ISHIHARA H 石原裕和