Mizutani Akihiro 水谷顕洋

… Alternative Names

MIZUTANI Akihiro 水谷顕洋

水谷顕洋ミズタニアキヒロ

Less

Researcher Number	30242861
Other IDs
Affiliation (Current)	2025: 昭和薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2018: 昭和薬科大学, 薬学部, 教授 2011 – 2014: 昭和薬科大学, 薬学部, 教授 2010: 独立行政法人理化学研究所, 発生神経生物研究チーム, 客員研究員 2008 – 2009: The Institute of Physical and Chemical Research, 発生神経生物研究チーム, 研究員 2007: The University of Tokyo, 医科学研究所, 助教 … More 2006: 東京大学, 医科学研究所, 助手 1996: Nagoya University, Assistant Professor, 医学部, 助手 1993 – 1994: 名古屋大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Neurochemistry/Neuropharmacology / General pharmacology / Molecular biology / Functional biochemistry Except Principal Investigator General pharmacology
Keywords	Principal Investigator IRBIT / トリパータイトシナプス / NBCe1 / 多重リン酸化 / IP3レセプター / リン酸化 / 核移行 / アネキシンXI / シナプス間隙のpH調節 / pH of synaptic cleft … More / tripartite synapse / surface expression / dephosphorylation / calcineurin / astrocyte processes / NBCe1-C / グリア細胞 / 細胞内pH / 細胞内Ca2+シグナル / 神経可塑性 / 神経伝達 / IP3R / multiple phosphorylation / マスター調節因子 / 細胞外環境センサー / ストレス反応 / 細胞外環境応答 / 多重リン酸化領域 / シナプス可塑性 / 小脳 / 欠失変異cDNA / 哺乳類培養細胞 / src癌遺伝子 … More Except Principal Investigator Computer simulation / Drug design / Structure-activity relationship / Tertiary structure / Inhibitor / Protein kinase / Intracellular signal transduction / 分子基礎理論 / 活性調節部位 / 有機合成 / 分子設計 / 特異的阻害剤 / コンピューターシュミレーション / 創薬 / 蛋白質立体構造 / 構造活性相関 / 阻害剤 / 蛋白質リン酸化酵素 / 細胞内シグナリング / PROTEIN KINASE CASCADES / CALMODULIN-DEPENDENT PROTEIN KINASE / CALMODULIN / CALCIUM SIGNAL TRANSDUCTION / 活性化メカニズム / カルモデュリンキナーゼV活性化因子 / カルモデュリンキナーゼV / カルモデュリン依存性キナーゼ / プロテインキナーゼカスケード / カルモデュリンキナーゼ / カルモデュリン / カルシウムシグナリング / 3D-structure / NMR / Ca^<2+>-binding proteins / annexinXI / Calcyclin / 高次構造変換 / 細胞内局在 / NMR解析 / アネキシンXI / 高次構造 / 核磁気共鳴法 / カルシウム結合蛋白質 / アネキシン / カルサイクリン / 多剤耐性 / GST / P-糖蛋白質 / CKA-1083 / W-77 Less

Roles of the pH regulation through HCO3- transporters in perisynaptic astrocytesPrincipal Investigator
- Principal Investigator
  
  MIZUTANI Akihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Showa Pharmaceutical University
Clarifying the role of IRBIT in the coupling regulation of intracellular pH and Ca2+ in astrocytes.Principal Investigator
- Principal Investigator
  
  MIZUTANI Akihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Showa Pharmaceutical University
Functional elucidation of IRBIT, a master regulator in the central nervous systemPrincipal Investigator
- Principal Investigator
  
  MIZUTANI Akihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Showa Pharmaceutical University
  The Institute of Physical and Chemical Research
Possible function of IP3 receptor as a non-channel moleculePrincipal Investigator
- Principal Investigator
  
  MIZUTANI Akihiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research
  The University of Tokyo
アネキシンXIの核内移行機構解明Principal Investigator
- Principal Investigator
  
  水谷顕洋
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Nuclear magnetic resonance studies of calcyclin and annexin XI.
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya University
ELUCIDATION OF THE INTRACELLULAR CALCIUM SIGNAL TRANSDUCTION WITH THE MOLECULAR PHARMACOLOGICAL APPROARCH
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  NAGOYA UNIVERSITY
Molecular basis and generation of new compounds for probing phosphorylation-mediated signaling pathways
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
卵巣癌細胞における抗癌剤耐性克服薬の創製とその薬理作用機構の解明
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
アネキシンXIの核内移行機構解明Principal Investigator
- Principal Investigator
  
  水谷顕洋
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University

All 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2000

All Journal Article Presentation Patent

[Journal Article] Calcineurin Binds to a Unique C-Terminal Region of NBCe1-C, the Brain Specific Isoform of NBCe1 and Enhances its Surface Expression2019
- Author(s)
  Hasegawa N, Hatano N, Tohyama S, Kita S, Mikoshiba K, Mizutani A.
- Journal Title
  
  BPB Reports
  
  Volume: 2 Pages: 7-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07068
[Journal Article] Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins.2017
- Author(s)
  Kawaai K, Ando H, Satoh N, Yamada H, Ogawa N, Hirose M, Mizutani A, Bonneau B, Seki G, Mikoshiba K.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 114(15) Issue: 15 Pages: 3921-3926
- DOI
  10.1073/pnas.1618514114
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07075, KAKENHI-PROJECT-16K07068, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-17H00588
[Journal Article] IRBIT is novel determinant of catecholamine homeostasis through the TH phosphorylation by CaMKIIα2015
- Author(s)
  Katsuhiro Kawaai, Akihiro Mizutani, Hirotaka Shoji, Naoko Ogawa, Etsuko Ebisui, Yukiko Kuroda, Shigeharu Wakana, Tsuyoshi Miyakawa, Chihiro Hisatsune, Katsuhiko Mikoshiba
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 未定 Issue: 17 Pages: 5515-5520
- DOI
  10.1073/pnas.1503310112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500451, KAKENHI-PROJECT-24590332, KAKENHI-PROJECT-15K06761, KAKENHI-PUBLICLY-15H01297, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-25242078
[Journal Article] Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice.2013
- Author(s)
  Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S
- Journal Title
  
  Gastroenterology
  
  Volume: S0016-5085(13) Issue: 1 Pages: 232-241
- DOI
  10.1053/j.gastro.2013.03.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458, KAKENHI-PROJECT-24590332, KAKENHI-PROJECT-24591225, KAKENHI-PROJECT-24700389, KAKENHI-PROJECT-25221002
[Journal Article] Cot Kinase Promotes Ca2+ Oscillation/Calcineurin-independent Osteoclastogenesis by Stabilizing NFATc1 Protein2012
- Author(s)
  Kuroda Y
- Journal Title
  
  Mol Cell Biology
  
  Volume: 32(14) Issue: 14 Pages: 2954-63
- DOI
  10.1128/mcb.05611-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220007, KAKENHI-PROJECT-23790265, KAKENHI-PROJECT-24500451, KAKENHI-PROJECT-24590332
[Journal Article] Syntaxin 1B Suppresses Macropinocytosis and Semaphorin 3A-Induced Growth Cone Collapse2011
- Author(s)
  Kabayama H
- Journal Title
  
  J Neurosci
  
  Volume: 31(20) Issue: 20 Pages: 7357-64
- DOI
  10.1523/jneurosci.2718-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220007, KAKENHI-PROJECT-21570190, KAKENHI-PROJECT-21590196, KAKENHI-PROJECT-23590274
[Journal Article] IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.2011
- Author(s)
  Yang D, Li Q, So I, Huang CL, Ando H, Mizutani A, Seki G, Mikoshiba K, Thomas PJ, Muallem S.
- Journal Title
  
  J Clin Invest
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570190
[Journal Article] IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway2011
- Author(s)
  Yang D
- Journal Title
  
  J Clin Invest
  
  Volume: 121(3) Issue: 3 Pages: 956-65
- DOI
  10.1172/jci43475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220007, KAKENHI-PROJECT-21570190
[Journal Article] Isolation of inositol 1, 4, 5-trisphosphate receptor-associating proteins and selective knockdown using RNA interference2010
- Author(s)
  Mizutani A, Kawaai K, Hisatsune C, Ando H, Michikawa T, Mikoshiba K
- Journal Title
  
  Methods Mol Biol
  
  Volume: 645 Pages: 133-41
- DOI
  10.1007/978-1-60327-175-2_9
- ISBN
  9781603271745, 9781603271752
- Data Source
  KAKENHI-PROJECT-21570190
[Journal Article] Isolation of inositol 1,4,5-trisphosphate receptor-associating proteins and selective knockdown using RNA interference.2010
- Author(s)
  Mizutani A, Kawaai K, Hisatsune C, Ando H, Michikawa T, Mikoshiba K
- Journal Title
  
  Methods Mol Biol
  
  Volume: 645 Pages: 133-141
- Data Source
  KAKENHI-PROJECT-21570190
[Journal Article] An IRBIT homologue lacks binding activity to inositol 1, 4, 5-trisphosphate receptor due to the unique N-terminal appendage2009
- Author(s)
  Ando H, Mizutani A, Mikoshiba K.
- Journal Title
  
  J.Neurochem 109
  
  Pages: 539-550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570190
[Journal Article] Inositol 1, 4, 5-triphosphate receptor-binding protein released with Inositol 1, 4, 5-triphosphate(IRBIT), associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation2009
- Author(s)
  Kiefer H, Mizutani A, Iemura A, Natsume T, Ando H, Kuroda Y, Mikoshiba K
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 10694-10705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570190
[Journal Article] IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct2009
- Author(s)
  Yang D, Shcheynikov N, Zeng W, Ohana E, So I, Ando H, Mizutani A, Mikoshiba K, Muallem S.
- Journal Title
  
  J Clin Invest. 119
  
  Pages: 193-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570122
[Journal Article] IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct2009
- Author(s)
  Yang D, Shcheynikov N, Zeng W, Ohana E, So I, Ando H, Mizutani A, Mikoshiba K, Muallem S
- Journal Title
  
  J.Clin.Invest. 119
  
  Pages: 193-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570190
[Journal Article] Phosphorylation of Homer3 by CaMKII regulates a coupling state of its target molecules in Purkinje Cells.2008
- Author(s)
  Mizutani, A, et. al.
- Journal Title
  
  J. Neuroscience (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570122
[Journal Article] Phosphorylation of Homer3 by calcium/calmodulin-dependent kinase II regulates a coupling state of its target molecules in Purkinje cells2008
- Author(s)
  Mizutani A, Kuroda Y, Futatsugi A, Furuichi T, Mikoshiba K.
- Journal Title
  
  J. Neurosci. 28
  
  Pages: 5369-6382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570122
[Journal Article] Phosphorylation of Homer3 by calcium/calmodulin-dependent kinase II regulates a coupling state of its target molecules in Purkinje cells2008
- Author(s)
  A. Mizutani
- Journal Title
  
  J. Neuroscience 28
  
  Pages: 5369-6382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570122
[Journal Article] 2-Aminoethyl diphenylborinate analogues: Selective inhibition for store-operated Ca^<2+> entry2007
- Author(s)
  Zhou H, Iwasaki H, Nakamura T, Nakamura K, Maruyama T, Hamano S, Ozaki S, Mizutani A, Mikoshiba K.
- Journal Title
  
  Biochem. Biophys. Res.Commun. 352
  
  Pages: 277-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570122
[Journal Article] IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor in a phosphorylation-dependent manner2006
- Author(s)
  Ando H, Mizutani A, Kiefer H, Tsuzurugi D, Michikawa T, & Mikoshiba K.
- Journal Title
  
  Mol. Cell 22
  
  Pages: 795-806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570122
[Journal Article] The role of Ca2+ signaling in cell function with special reference to exocrine secretion2000
- Author(s)
  Mikoshiba K, Hisatsune C, Futatsugi A, Mizutani A, Nakamura T, Miyachi K.
- Journal Title
  
  Cornea 27, Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570122
[Patent] IP3受容体結合タンパク質による細胞内標的分子の制御2007
- Inventor(s)
  御子柴克彦、水谷顕洋、安東英明
- Industrial Property Rights Holder
  独立行政法人理化学研究所・独立行政法人科学技術振興機構
- Industrial Property Number
  2007-073396
- Filing Date
  2007-03-20
- Data Source
  KAKENHI-PROJECT-18570122
[Presentation] IRBIT, an integrative regulator of intracellular Ca2+ signals and pH environment2018
- Author(s)
  水谷顕洋
- Organizer
  第９５回日本生理学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07068
[Presentation] カルシニューリンが脳型NBCe1の細胞内局在に与える影響2018
- Author(s)
  長谷川尚美, 遠山卓, 波多野直哉, 水谷顕洋
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07068
[Presentation] Long-IRBIT と陰イオン交換体のpH 依存的な相互作用は、細胞移動を制御する2018
- Author(s)
  伊藤諒、濵田浩一、川崎聡子、波多野直哉、御子柴克彦、水谷顕洋
- Organizer
  第138回日本薬学会
- Data Source
  KAKENHI-PROJECT-16K07068
[Presentation] Long-IRBITは陰イオン交換体の活性を調節して細胞移動を制御している。2017
- Author(s)
  伊藤諒、濱田浩一、川崎聡子、御子柴克彦、水谷顕洋
- Organizer
  第４０回日本分子生物学会年会2017
- Data Source
  KAKENHI-PROJECT-16K07068
[Presentation] 中枢神経系における脳型NBCe1の細胞膜輸送に関わる分子について2017
- Author(s)
  長谷川尚美、柏木舞、遠山卓、森滉貴、濵田浩一、水谷顕洋
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K07068
[Presentation] 脳型NBCe1の細胞内局在に関わる結合分子の役割2017
- Author(s)
  長谷川尚美、森滉貴、竹中遥菜、白鳥瞳、水谷顕洋
- Organizer
  第４０回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07068
[Presentation] アストロサイトにおける脳型NBCe1の膜局在に関わる結合分子の役割2016
- Author(s)
  長谷川尚美、遠山卓、森滉貴、竹中遥菜、白鳥瞳、波多野直哉、水谷顕洋
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07068
[Presentation] IRBITのpNBCへの結合と活性には、IRBITのcasein kinase IIによるリン酸化が必須である。2012
- Author(s)
  水谷顕洋、山田秀臣、山崎脩、関常司、御子柴克彦
- Organizer
  第８５回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡市）
- Data Source
  KAKENHI-PROJECT-24590332
[Presentation] Multi-site phosphorylation regulates the target recognition of IRBIT2011
- Author(s)
  水谷顕洋
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21570190
[Presentation] IRBITの多重リン酸化領域におけるリン酸化パターンによって、IRBITの標的分子との相互作用が規定される2011
- Author(s)
  水谷顕洋、御子柴克彦
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21570190
[Presentation] IRBITの中枢神経系における分布について2009
- Author(s)
  水谷顕洋、黒田有希子、安東英明、永吉旭土、河合克宏、御子柴克彦
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場 1号館1階イベントホール
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-21570190
[Presentation] Purkinje細胞におけるHomer3 のリン酸化2008
- Author(s)
  水谷顕洋、黒田有希子、古市貞一、御子柴克彦
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18570122

1. HIDAKA Hiroyoshi (80100171)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. OKAZAKI Katsuo (20252231)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. WATANABE Yasuo (10273228)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NIKI Ichiro (10262908)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KAWAAI Katsuhiro (00553653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. YOKOKURA Hisayuki (90273242)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HATANO Naoya (10332280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SEKI Jouji (30206619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. HAGIWARA Masatoshi (10208423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAKAKIBARA Zinsaku (70080182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 渡辺正人 (30220924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SASTRY Mallika

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. LUBIENSKI Michael

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. POTTS Barbara C

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. CHAZIN Walter J

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. LUBIENSKI M

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. POTTS Barba

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. CHAZIN Walt

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 久恒智博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 安東英明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizutani Akihiro 水谷 顕洋

MIZUTANI Akihiro 水谷 顕洋

水谷 顕洋 ミズタニ アキヒロ

Research Projects

Research Products

Co-Researchers

Roles of the pH regulation through HCO3- transporters in perisynaptic astrocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarifying the role of IRBIT in the coupling regulation of intracellular pH and Ca2+ in astrocytes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional elucidation of IRBIT, a master regulator in the central nervous systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Possible function of IP3 receptor as a non-channel moleculePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アネキシンXIの核内移行機構解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nuclear magnetic resonance studies of calcyclin and annexin XI.

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ELUCIDATION OF THE INTRACELLULAR CALCIUM SIGNAL TRANSDUCTION WITH THE MOLECULAR PHARMACOLOGICAL APPROARCH

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis and generation of new compounds for probing phosphorylation-mediated signaling pathways

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

卵巣癌細胞における抗癌剤耐性克服薬の創製とその薬理作用機構の解明

Principal Investigator

Project Period (FY)

Research Category

Research Institution

アネキシンXIの核内移行機構解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Calcineurin Binds to a Unique C-Terminal Region of NBCe1-C, the Brain Specific Isoform of NBCe1 and Enhances its Surface Expression2019

Author(s)

Journal Title

Data Source

[Journal Article] Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IRBIT is novel determinant of catecholamine homeostasis through the TH phosphorylation by CaMKIIα2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice.2013

Author(s)

Mizutani Akihiro 水谷顕洋

MIZUTANI Akihiro 水谷顕洋

水谷顕洋ミズタニアキヒロ