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KIMURA Takafumi  木村 貴文

ORCIDConnect your ORCID iD *help
Researcher Number 30275193
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2003 – 2005: 京都府立医科大学, 医学研究科, 助手
1996 – 1999: 京都府立医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Hematology / Hematology
Except Principal Investigator
Hematology / Hematology / Biological Sciences
Keywords
Principal Investigator
flow cytometry / xenotransplantation / hematopoietic stem cell / フローサイトメトリー / 異種間移植 / 造血幹細胞 / gp130 / acute myelogeneous leukemia / interleukin-11 / テロメラーゼ活性 / インターロイキン-6受容体 / ヒト造血前駆細胞 … More
Except Principal Investigator
… More 造血幹細胞 / IL-3 / c-kit / gp130 / CXCR4 / SDF-1 / IL-6 / 造血シグナル / Intra-bone marrow injection (IBMI) / SCID-repopulating cell (SRC) / hematopoietic stem cell / 臍帯血移植 / セルソーター / migration ability / CD34 antigen / cord blood stem cell transplantation / intra-bone marrow injection(IBMI) / Intra-bone marrow injection(IBMI) / 遊走能 / SCID-repopulating cell(SRC) / CD34抗原 / transcription factor / crosstalk / hematopoietic signal / チロシンキナーゼ / アンチセンスDNA / 転写因子 / クロストーク / Intra-bone marrow injection(IBMI)法 / トランスレーショナルリサーチ / Intra-bone marrow injection (IBMI)法 / 再生医療 / 可塑性 / 可溶性IL-6受容体 / MS-5 / 芽球コロニー形成法 Less
  • Research Projects

    (7 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (6 People)
  •  A challenge for long-term human lymphohemopoietic reconstitution in mice with normal immunityPrincipal Investigator

    • Principal Investigator
      KIMURA Takafumi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  骨髄腔内直接移植法を用いる体性あるいは胚性幹細胞の可塑性の解明

    • Principal Investigator
      薗田 精昭
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kansai Medical University
      Kyoto Prefectural University of Medicine
  •  Identification of novel human cord blood-derived CD34-negative SCID-repopulating cells and clarification of their stem cell characteristics -Application of the intra-bone marrow injection (IBMI) method

    • Principal Investigator
      SONODA Yoshiaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kansai Medical University
      Kyoto Prefectural University of Medicine
  •  ヒト未分化造血幹細胞のin vitro測定系の確立と多分化能の解析Principal Investigator

    • Principal Investigator
      木村 貴文
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Hematology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  細胞系列特異的因子に依存しない血球産生機構の解明

    • Principal Investigator
      薗田 精昭
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Analysis of crosstalks between hematopoietic signals and their molecular mechanisms

    • Principal Investigator
      SONODA Yoshiaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  芽球コロニー形成法を用いるヒト未分化造血幹細胞の増殖分化シグナルの解析

    • Principal Investigator
      SONODA Yoshiaki
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2005 2004 2003 2002 Other

All Journal Article Patent

  • [Journal Article] Identification and hematopoietic potential of CD45^- clonal cells with very immature phenotype (CD45^-CD34^-CD38^-Lin^-) in patients with myelodysplastic syndromes.2005

    • Author(s)
      Ogata K, Satoh C, Tachibana M, Hyodo H, Tamura H, Dan K, Kimura T, Sonoda Y, Tsuji T.
    • Journal Title

      Stem Cells 23

      Pages: 619-630

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Identification and hematopoietic Potential of CD45^- clonal cells with very immature phenotype (CD45^-CD34^-CD38^-Lin^-) in patients with myelodysplastic syndromes.2005

    • Author(s)
      Ogata K, Satoh C, Tachibana M, Hyodo H, Tamura H, Dan K, Kimura T, Sonoda Y, Tsuji T
    • Journal Title

      Stem Cells 23

      Pages: 619-630

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] Identification and hematopoietic potential of CD45^- clonal cells with very immature phenotype (CD45^-CD34^-CD38^-Lin^-)in patients with myelodysplastic syndromes.2005

    • Author(s)
      Ogata K, Satoh C, Tachibana M, Hyodo H, Tamura H, Dan K, Kimura T, Sonoda Y, Tsuji T.
    • Journal Title

      Stem Cells 23

      Pages: 619-630

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Identification and hematopoietic potential of CD45^- clonal cells with very immature phenotype (CD45^-CD34^-CD38^-Lin^-) in patients with myelodysplastic --2005

    • Author(s)
      Ogata K, Satoh C, Tachibana M, Kimura T, Sonoda Y, Tsuji T, et al.
    • Journal Title

      Stem Cells 23

      Pages: 619-630

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] The sphingosine 1-phosphate agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34^+ progenitor cells.2004

    • Author(s)
      Kimura T, Boehmler AM, Seitz G, Kuci S, Wiesner T, Brinkmann V, Kanz L, MOhle R.
    • Journal Title

      Blood 103

      Pages: 4478-4486

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Impaired stem cell functions of CD34^+ cells selected by two different immunomagnetic beads systems.2004

    • Author(s)
      Kimura T, Minamiguchi H, Wang J, Kaneko H, Nakagawa H, Fujii H, Sonoda Y
    • Journal Title

      Leukemia 18

      Pages: 566-574

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] Proliferative and migratory potentials of human cord blood-derived CD34^- severe combined immunodeficiency repopulating cells that retain secondary reconstituting capacity.2004

    • Author(s)
      Kimura T, Wang J, Matsui K, Imai S, Yokoyama S, Nishikawa M, Ikehara S, Sonoda Y.
    • Journal Title

      Int.J.Hematol. 79

      Pages: 328-333

    • NAID

      10013081994

    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Proliferative and migratory potentials of human cord blood-derived CD34-negative SCID-repopulating cells that tetain secondary reconstituting capacity2004

    • Author(s)
      Kimura T, Wang J, Matsui K, Imai S, Yokoyama S, Ikehara S, Sonoda Y
    • Journal Title

      Int J Hematol 79

      Pages: 328-333

    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] Proliferative and migratory potentials of human cord blood-derived CD34-negative SCID-repopulating cells that retain secondary reconstituting capacity2004

    • Author(s)
      Kimura T, Wang J, Matsui K, Imai S, Yokoyama S, Ikehara S, Sonoda Y
    • Journal Title

      Int J Hematol 79

      Pages: 328-333

    • Data Source
      KAKENHI-PROJECT-15039227
  • [Journal Article] Preferential expression of the vasoactive intestinal peptide (VIP) receptor VPAC1 in human cord blood-derived CD34^+CD38^- cells : possible role of VIP as a growth-promoling factor for hematopoietic stem/ progenitor cells.2004

    • Author(s)
      M, Kimura T, Kishimoto Y, Tatekawa T, Baba Y, Nishizaki T, Matsuzaki N, Taniguchi Y, Yoshihara S, Ikegame K, Shirakata T, Nishida S, Masuda T, Hosen N, Tsuboi A, Oji Y, Oka Y, Ogawa H, Sonoda Y, Sugiyama H, Kawase I, Soma T.
    • Journal Title

      Leikemia 18

      Pages: 912-921

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Impaired stem cell function of CD34^+ cells selected by two different immunomagnetic beads sysytem2004

    • Author(s)
      Kimura T, Minamiguchi H, Wang J, Kaneko H, Nakagawa H, Sonoda Y
    • Journal Title

      Leukemia 18

      Pages: 566-574

    • Data Source
      KAKENHI-PROJECT-15039227
  • [Journal Article] Preferential expression of the vasoactive intestinal peptide(VIP) receptor VPAC1 in human cord blood-derived CD34^+CD38^- cells : possible role of ---2004

    • Author(s)
      Kawakami M, Kimura T, Kishimoto Y, Takekawa T, Sonoda Y, et al.
    • Journal Title

      Leukemia 18

      Pages: 912-921

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] Proliferative and migratory potentials of human cord blood-derived CD34^- severe combined immunodeficiency repopulating cells that retain secondary reconstituting capacity.2004

    • Author(s)
      Kimura T, Wang J, Matsui K, Imai S, Yokoyama S, Nishikawa M, Ikehara S, Sonoda Y
    • Journal Title

      Int J Hematol 79

      Pages: 328-333

    • NAID

      10013081994

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] Preferential expression of the vasoactive intestinal peptide (VIP) receptor VPAC1 in human cord blood-derived CD34^+CD38^-cells : possible role of VIP as a growth-promoting factor for hematopoietic stem/progenitor cells.2004

    • Author(s)
      Kawakami M, Kimura T, Kishimoto Y, Tatekawa T, Baba Y, Nishizaki T, Mtsuzaki N, Taniguchi Y, Yoshihara S, Ikegami K, Shirakata T, Nishida S, Masuda T, Hosen N, Tsuboi A, Oji Y, Oka Y, Ogawa H, Sonoda Y, Sugiyama H, Kawase I, Soma T
    • Journal Title

      Leukemia 18

      Pages: 912-921

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] Preferential expression of the vasoactive intestinal peptide (VIP) receptor VPAC1 in human cord blood-derived CD34^+CD38^-cells : possible role of VIP as a growth- promoting factor for hematopoietic stem/ progenitor cells.2004

    • Author(s)
      Kawakami M, Kimura T, Kishimoto Y, Tatekawa T, Baba Y, Nishizaki T, Matsuzaki N, Taniguchi Y, Yoshihara S, Ikegame K, Shirakata T, Nishida S, Masuda T, Hosen N, Tsuboi A, Oji Y, Oka Y, Ogawa H, Sonoda Y, Sugiyama H, Kawase I, Soma T.
    • Journal Title

      Leukemia 18

      Pages: 912-921

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Proliferative and migratory potentials of human cord blood-derived CD34 negative SCID-repopulating cells that retain secondary reconstituting capacity2004

    • Author(s)
      Kimura T, Wang J, Matsui K, Imai S, Yokoya S, Ikehara S, Sonoda Y
    • Journal Title

      Int J Hematol 79

      Pages: 328-333

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] The sphingosine 1-phosphate agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34^+ progenitor cells.2004

    • Author(s)
      Kimura T, Boehmler AM, Seitz G, Kuci S, Wiesner T, Brinkmann V, Kanz L, Mohle R.
    • Journal Title

      Blood 103

      Pages: 4478-4486

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Impaired stem cell function of CD34^+ cells selected by two different immunomagnetic beads systems.2004

    • Author(s)
      Kimura T, Minamiguchi H, Wang J, kaneko H, Nakagawa H, Fujii H, Sonoda Y.
    • Journal Title

      Leukemia 18

      Pages: 566-574

    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Impaired stem cell function of CD34^+ cells selected by two different immunomagnetic beads system2004

    • Author(s)
      Kimura T, Minamiguchi H, Wang J, Kaneko H, Nakagawa H, Sonoda Y
    • Journal Title

      Leukemia 18

      Pages: 566-574

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] Preferential expression of the vasoactive intestinal peptide (VIP) receptor VPAC1 in human cord blood-derived CD34^+CD38^- cells : possible role of ---2004

    • Author(s)
      Kawakami M, Kimura T, Kishimoto Y, Tatekawa T, Sonoda Y et al.
    • Journal Title

      Leukemia 18

      Pages: 912-921

    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] The sphingosine 1-phosphate agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34^+ progenitor cells.2004

    • Author(s)
      Kimura T.Boehmler AM, Seitz G, Kuci S, Wiesner T, Brinkmann V, Kanz L, Mohle R.
    • Journal Title

      Blood 103

      Pages: 4478-4486

    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Impaired stem cell function of CD34^+ cells selected by two different immunomagnetic beads sysytem2004

    • Author(s)
      Kimura T, Minamiguchi H, Wang J, Kaneko H, Nakagawa H, Sonoda Y
    • Journal Title

      Leukemia 18

      Pages: 566-574

    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] SCID-repopulating cell activity of human cord blood-derived CD34^- cells assured by intra-bone marrow injection2003

    • Author(s)
      Wang J, Kimura T, Asada R, Hrada S, Ikehara S, Sonoda Y, et al.
    • Journal Title

      Blood 101(8)

      Pages: 2924-2931

    • Data Source
      KAKENHI-PROJECT-15039227
  • [Journal Article] SCID-repopulating cell activity of human cord blood-derived CD34 cells assured by intra-bone marrow injection.2003

    • Author(s)
      Wang J, Kimura T, Asada R, Harada S, Ikehara S, Sonoda Y, et al.
    • Journal Title

      Blood 101(8)

      Pages: 2924-2931

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] SCID-repopulating cell activity of human cord blood-derived CD34^- cells assured by intra-bone marrow infection2003

    • Author(s)
      Wang J, Kimura T, Asada R, Harada, S.Ikehara S.Sonoda Y, et al.
    • Journal Title

      Blood 101(8)

      Pages: 2924-2931

    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] SCID-repopulating cell activity of human cord blood-derived CD34^- cells assured by intra-bone marrow injection.2003

    • Author(s)
      Wang J, Kimura T, Asada R, Harada S, Yokota S, Kawamoto Y, Fujimura Y, Tsuji T, Ikehara S, Sonoda Y
    • Journal Title

      Blood 101

      Pages: 2924-2931

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Journal Article] Preferential expression of the vasoactive intestinal peptide (VIP) receptor VPAC1 in human cord blood-derived CD34^+CD38^- cells : possible role of --

    • Author(s)
      Kawakami M, Kimura T, Kishimoto Y, Takekawa T, Sonoda Y et al.
    • Data Source
      KAKENHI-PROJECT-15039227
  • [Patent] 臍帯血・骨髄・末梢血等における新規な幹細胞集団2003

    • Inventor(s)
      薗田 精昭, 木村 貴文
    • Industrial Property Rights Holder
      キリンビール株式会社
    • Filing Date
      2003-07-04
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Patent] 臍帯血、骨髄、抹消血等における新規な幹細胞集団2002

    • Inventor(s)
      薗田精昭, 木村貴文
    • Industrial Property Rights Holder
      キリンビール株式会社
    • Industrial Property Number
      2002-187793
    • Filing Date
      2002-07-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591015
  • [Patent] 臍体血、骨髄、抹消血等における新規な幹細胞集団2002

    • Inventor(s)
      薗田 精昭, 木村 貴大
    • Industrial Property Rights Holder
      キリンビール株式会社
    • Industrial Property Number
      2002-187793
    • Filing Date
      2002-07-05
    • Data Source
      KAKENHI-PROJECT-15039227
  • 1.  SONODA Yoshiaki (60206688)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 24 results
  • 2.  IKEHARA Susumu (90108986)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  横田 昇平 (80231687)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  OKUDA Tsukasa (30291587)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MURAKAMI Akira (60210001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAKAZU Naoki (20264757)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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