sakurada chikai 桜田誓

… Alternative Names

桜田誓サクラダチカイ

SAKURADA Chikai 桜田誓

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Researcher Number	30279244
Other IDs
External Links
Affiliation (Current)	2025: 日本薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 日本薬科大学, 薬学部, 教授 2014 – 2017: 日本薬科大学, 薬学部, 教授 2006 – 2008: Nihon Pharmaceutical University, Associate professor, 薬学部, 准教授 2004 – 2005: Nihon Pharmaceutical University, Associate professor, 薬学部, 助教授 2002 – 2003: Daiichi College of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, associate professor, 薬学部, 助教授 2000 – 2001: 第一薬科大学, 薬学部, 講師 1996: 第一薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Neurochemistry/Neuropharmacology / 医薬分子機能学 Except Principal Investigator Biological pharmacy / Functional basic dentistry / 応用薬理学・医療系薬学 / Natural medicines
Keywords	Principal Investigator 疼痛 / 代謝 / ノシセプチン / 化学療法誘発性末梢神経障害 / 末梢神経障害 / オキサリプラチン / 構造活性相関 / 鎮痛 / シノメニン誘導体 / シノメニン … More / synaptic membranes / mouse brain / metabolic pathway / endomorphin-2 / dipeptidyl peptidase IV / antinociception / エンドモルフィン / 鎮痛薬 / ジペプチジルペプチダーゼIV / エンドモルフィン-1 / ペプチダーゼ / 脳神経疾患 / モルヒネ / 痴呆 / 海馬 / 脳・神経 / 薬理学 / エンドペプチダーゼ-24.11 / シナプス膜標品 / エンドペプチダーゼ 24.11 / 脊髄 / クローニング / 受容体 / ニューロキニン / サブスタンスP / 疼通 … More Except Principal Investigator RANKL / トランスジェニック / 副甲状腺ホルモン / 骨吸収 / Proteomics / Vitamin D metabolism / Bone mineral / Transgenic / Parathyroid hormone / Vitamin D / Renal osteodystrophy / Kidney / 糖尿病 / 腎炎 / カルシトニン / 副甲状腺 / 石灰化 / プロテオミックス / ビタミンD代謝 / 骨量 / ビタミンD / 腎性骨症 / 腎臓 / Periodontal disease / Long bone / Bone mineral density / Bone resorption / alveolar bone / transgenic mice / Interleukin 1 / LPS / OPG / トランスジェニックマウス / ドライスカル / 口腔内細菌 / サイトカイン / 破骨細胞 / 歯根膜 / 歯周病 / 低カルシウム / インターロイキン-1 / 歯槽骨 / opioid action / NK_1 receptor antagonist / pain-related behavior / intrathecal injection / substance P / ナロキソン / マウス脊髄シナプス膜標本 / サブスタンスPアナログ / オビオイド受容体 / NK_1受容体 / オピオイド作用 / NK_1受容体拮抗薬 / 疼痛関連行動 / 脊髄クモ膜下腔内投与 / サブスタンスP / アロディニア / 麻佛散 / 慢性障害性疼痛 / 腫瘍壊死因子 / 鎮痛 / モルヒナン / アルカロイド / 抗炎症 / 非オピオイド性鎮痛薬 / 神経障害性疼痛 / 鎮痛作用 / 抗侵害刺激作用 / シノメニン / 防己黄耆湯 Less

Study of pain relief of sinomenine and related compounds for chemotherapy-induced peripheral neuropathyPrincipal Investigator
- Principal Investigator
  
  桜田誓
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Nihon Pharmaceutical University
Effects of Kampo Extract Boiogito and Its Alkaloid Sinomenine on Nociceptive Pain
- Principal Investigator
  
  Takano Fumihide
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Nihon Pharmaceutical University
Development of anti-dementia drugs based on metabolism of nociceptin by synaptic membranes of hippocampus.Principal Investigator
- Principal Investigator
  
  SAKURADA Chikai
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nihon Pharmaceutical University
Evidence base treatment of renal osteodistropy
- Principal Investigator
  
  SHINKI Toshimasa
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nihon Pharmaceutical University
Mechanisms of bone resorption in alveolar bone of IL-1 transgenic mice
- Principal Investigator
  
  SHINKI Toshimasa
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon Pharmaceutical University
  Showa University
Development of a New Analgesic Based on Metabolism of Endomorphin, an Endogenous Opioid PeptidePrincipal Investigator
- Principal Investigator
  
  SAKURADA Chikai
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nihon Pharmaceutical University
  Daiichi University, College of Pharmaceutical Sciences
痛みの伝達・制御におけるノシセプチン代謝の重要性Principal Investigator
- Principal Investigator
  
  櫻田誓
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Development of a new analgesic drug with tachykinin antagonistic and opioid activities in the spinal cord
- Principal Investigator
  
  SAKURADA Tsukasa
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Daiichi College of Pharmaceutical Sciences
疼通を制御する新規ニューロキニン受容体のクローニングPrincipal Investigator
- Principal Investigator
  
  桜田誓
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences

All 2024 2023 2017 2016 2015 2009 2007 2006 2004 2003

All Journal Article Presentation

[Journal Article] Effects of Kampo Extract Boiogito and Its Alkaloid Sinomenine on Nociceptive Pain in Mouse Models2017
- Author(s)
  A. Kubota, H. Shindo, Y. Fukushima, T. Komatsu、T. Sakurada, T. Yasuda, S. Fushiya, Y. Kondo, C. Sakurada, F. Takano.
- Journal Title
  
  Pharmacometrics
  
  Volume: 92
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460126
[Journal Article] Effects of Kampo Extract Boiogito and Its Alkaloid Sinomenine on Nociceptive Pain in Mouse Models2017
- Author(s)
  A. Kubota, H. Shindo, Y. Fukushima, T. Komatsu, T. Sakurada, T. Yasuda, S. Fushiya, Y. Kondo, Sakurada, F. Takano
- Journal Title
  
  Pharmacometrics
  
  Volume: 92 Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460126
[Journal Article] Extracellular signal-regulated kinase(ERK) and nitric oxide synthase mediate intrathecal morphine-induced nociceptive behavior.2007
- Author(s)
  Takaaki Komatsu, Chikai Sakurada, Mika Sasaki, Kengo Sanai, Minoru Tsuzuki, Giacinto Bagetta, Shinobu Sakurada and Tsukasa Sakurada.
- Journal Title
  
  Neuropharmacology 52巻
  
  Pages: 1237-1243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590068
[Journal Article] morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascade.2007
- Author(s)
  Tsukasa Sakurada, Takaaki Komatsu, Hikari Kuwahata, Chizuko Watanabe, Toru Orito, Chikai Sakurada, Minoru Tsuzuki and Shinobu Sakurada.
- Journal Title
  
  Biochemical Pharmacology 74巻
  
  Pages: 758-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590068
[Journal Article] Development of a new analgesic based on metabolism of endomorphin, an endogenous opioid peptide2004
- Author(s)
  Chikai Sakurada
- Journal Title
  
  YAKUGAKU ZASSHI 124
  
  Pages: 549-554
- NAID
  110003614985
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590086
[Journal Article] Development of a New Analgesic Based on Metabolism of Endomorphin, an Endogenous Opioid Peptide2004
- Author(s)
  Chikai Sakurada
- Journal Title
  
  YAKUGAKU ZASSHI 124
  
  Pages: 549-554
- NAID
  110003614985
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590086
[Journal Article] Degradation of endomorphin-2 at the supraspinal level in mice is initiated by dipeptidyl peptidase IV : an in vitro and in vivo study2003
- Author(s)
  Chikai Sakurada 他5名
- Journal Title
  
  Biochemical Pharmacology 66
  
  Pages: 653-661
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590086
[Journal Article] Degradation of endomorphin-2 at the supraspinal level in mice is initiated by dipeptidyl peptidase IV : an in vitro and in vivo study2003
- Author(s)
  Chikai Sakurada et al.
- Journal Title
  
  Biochemical Pharmacology 66
  
  Pages: 653-661
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590086
[Presentation] ホルマリン誘発性急性疼痛抑制効果に対するシノメニン窒素原子上の置換基の影響2024
- Author(s)
  片岡裕樹、勝山壮、小笠原幸乃、岡田直子、齋藤俊昭、高野文英、櫻田誓
- Organizer
  日本薬学会第144年会（横浜）
- Data Source
  KAKENHI-PROJECT-22K06683
[Presentation] マウスにおけるホルマリン誘発性疼痛に対するシノメニン誘導体の抑制効果2023
- Author(s)
  片岡裕樹、勝山壮、小笠原幸乃、相川怜、田中夏未、岡田直子、齋藤俊昭、高野文英、櫻田誓
- Organizer
  日本薬学会第143年会（札幌）
- Data Source
  KAKENHI-PROJECT-22K06683
[Presentation] 華岡青洲処方『通仙散（麻佛散）』の抗侵害刺激作用について（2）2016
- Author(s)
  1.福島　康仁、水島　彩佳、石川　愛弓、塙　大介、塙大介、福田　彩、宮根浩一、伏谷眞二、櫻田　誓、高野　文英
- Organizer
  日本薬学会大136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26460126
[Presentation] 防己黄耆湯およびシノメニンの抗侵害刺激作用に関する研究2015
- Author(s)
  新藤　祐久、水島　彩佳、窪田　篤人、伏谷　眞二、櫻田　誓、高野　文英
- Organizer
  第59回　日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26460126
[Presentation] 華岡青洲処方『通仙散（麻佛散）』の抗侵害刺激作用について2015
- Author(s)
  2.福島　康仁、水島　彩佳、石川　愛弓、塙　大介、福田　彩、宮根浩一、伏谷眞二、櫻田　誓、高野　文英
- Organizer
  第59回　日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26460126
[Presentation] モルヒネ-3-グルクロニドマウス脊髄内投与に伴うグリア細胞におけるサイトカインの役割2009
- Author(s)
  小松生明、勝山壮、真井健吾、桜田誓、桜田忍、桜田司
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590068
[Presentation] モルヒネ3 -グルクロニドマウス脊髄内投与に伴うクリア細胞におけるサイトカインの役割2009
- Author(s)
  桜田誓, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-18590068
[Presentation] Morphine-3-glucuronide の脊髄クモ膜腔内投与により誘発される疼痛関連行動の発現機序について2006
- Author(s)
  小松生明、重野牧、佐々木美佳、桜田誓、都築稔、桜田忍、桜田司
- Organizer
  第79回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590068

1. SAKURADA Chikai (80124907)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. NAKAJIMA Takanori (80265404)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. Takano Fumihide (20236251)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. SHINKI Toshimasa (90138420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MIYAMOTO Youichi (20295132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAKAMI Masamichi (80307058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOBAYASHI Makoto (80186767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAMIJYO Ryutaro (70233939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 守村直子 (00349044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 勝山壮 (90433557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 片岡裕樹 (60805167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 斎藤俊昭 (00286882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

sakurada chikai 桜田 誓

桜田 誓 サクラダ チカイ

SAKURADA Chikai 桜田 誓

Research Projects

Research Products

Co-Researchers

Study of pain relief of sinomenine and related compounds for chemotherapy-induced peripheral neuropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of Kampo Extract Boiogito and Its Alkaloid Sinomenine on Nociceptive Pain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of anti-dementia drugs based on metabolism of nociceptin by synaptic membranes of hippocampus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evidence base treatment of renal osteodistropy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of bone resorption in alveolar bone of IL-1 transgenic mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a New Analgesic Based on Metabolism of Endomorphin, an Endogenous Opioid PeptidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

痛みの伝達・制御におけるノシセプチン代謝の重要性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new analgesic drug with tachykinin antagonistic and opioid activities in the spinal cord

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

疼通を制御する新規ニューロキニン受容体のクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of Kampo Extract Boiogito and Its Alkaloid Sinomenine on Nociceptive Pain in Mouse Models2017

Author(s)

Journal Title

Data Source

[Journal Article] Effects of Kampo Extract Boiogito and Its Alkaloid Sinomenine on Nociceptive Pain in Mouse Models2017

Author(s)

Journal Title

Data Source

[Journal Article] Extracellular signal-regulated kinase(ERK) and nitric oxide synthase mediate intrathecal morphine-induced nociceptive behavior.2007

Author(s)

Journal Title

Data Source

[Journal Article] morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascade.2007

Author(s)

Journal Title

Data Source

[Journal Article] Development of a new analgesic based on metabolism of endomorphin, an endogenous opioid peptide2004

Author(s)

Journal Title

NAID

sakurada chikai 桜田誓

桜田誓サクラダチカイ

SAKURADA Chikai 桜田誓

[Presentation] モルヒネ-3-グルクロニドマウス脊髄内投与に伴うグリア細胞におけるサイトカインの役割2009

[Presentation] モルヒネ3 -グルクロニドマウス脊髄内投与に伴うクリア細胞におけるサイトカインの役割2009