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ABEYAMA Kazuhiro  阿邉山 和浩

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… Alternative Names

阿邊山 和浩  アベヤマ カズヒロ

阿部山 和浩  アベヤマ カズヒロ

阿辺山 和浩  アベヤマ カズヒロ

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Researcher Number 30284897
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2009: 鹿児島大学, 大学院・医歯学総合研究科, 客員研究員
2007 – 2008: Kagoshima University, Graduate School of Medical and Dental Sciences, Research Associate Professor
2005 – 2006: 鹿児島大学, 大学院医歯学総合研究科, 客員助教授
2004 – 2006: Kagoshima University, Graduate School of Medical and Dental Sciences, Visiting Associate Professor, 大学院・医歯学総合研究科, 客員助教授
2003: 鹿児島大学, 大学院・医歯学総合研究科, 助手
2002: 聖マリアンナ医大, 医学部, 助手
Review Section/Research Field
Principal Investigator
Emergency medicine / General internal medicine (including Psychosomatic medicine) / Radiation science
Except Principal Investigator
Neurology / Hematology / Drug development chemistry / Laboratory medicine / Emergency medicine / Digestive surgery / Pediatric surgery / Laboratory medicine
Keywords
Principal Investigator
HMGB1 / lethality / sepsis / anti-inflammatory peptide / DIC / thrombomodulin / 1,5-AG / 1,5-AF / 細胞周期 / 抗炎症作用 … More / アポプトーシス / メイラード反応 / アスコパイロン-P / HMGBI / 嫌気 / APP / 炎症 / 低酸素・嫌気代謝 / 敗血症・多臓器不全 / HMGB1蛋白 / Ascopyrone-P (APP) / decoy ODN / NF-kB / anti-inflammatory oligonucleotide … More
Except Principal Investigator
VEGF / HMGB1 / HMGB-1 / POEMS syndrome / Crow-Fukase syndrome / ARDS / RAGE / IL-8 / THP-1 / β2-microglobulin / 敗血症 / DIC / megakaryocyte / platelet / vascular endothelial growth factor / 敗血症性ショック / inflammation / sepsis / human antibody phage library / ペプチド / 阻害剤 / 抗体医薬 / 炎症 / ヒト抗体ファージライブラリ / nerve / brain / peptidome / proteomics / proteome / Syndrome / 神経 / 脳 / syndrome / プロテオミクス / プロテオーム / POEMS / Crow-Fukase / unfolded protein resnonce / ER stress / dialysis related amyloidosis / hemodialysis / 蛋白折り畳み異常 / 小胞体ストレス / 透析アミロイド症 / 血液透析 / radical / sprvqis / ock / thromb in / hrombomodulin / 免疫学 / 循環器・高血圧 / 救命 / 播種性血管内凝固症候群(DIC) / ラディカル / ショック / トロンビン / トロンボモデュリン / B cell / embryonic lethality / diabetic retinopathy / atherosclerosis / transgenic mouse / B細胞 / 胎生致死 / 骨髄巨核球 / 血小板 / POEMS症候群 / Crow-Fukase症候群 / ALI / septic shock / 2-arachidonylglyceorol / anandamide / endocannabinoides / High Mobility Group Box-1 / endocannabinoid / 2-arachidonylglycerol(2-AG) / 感染症性ショック / 急性肺障害(ALI) / 2-アラキドニールグリセロール / アナンダマイド / 内因性マリファナ / 肝細胞癌 / ケモカイン / 食道癌 / 肝癌 / 炎症と癌化 / Carcinogenseis / Esophageal ca / HCC / 超低出生体重児 / マイクロアレイ / ミコナゾール / 壊死性腸炎 / 新生児 / 消化管穿孔 / 病理学 / 微生物 / 細菌 / 感染症 / 個体死 / 核内蛋白 / アポトーシス / 細胞壊死 / 多臓器不全 / HMG-1 / TNFα Less
  • Research Projects

    (15 results)
  • Research Products

    (71 results)
  • Co-Researchers

    (21 People)
  •  Identification of Perpetuating Factor for Liver Tissue Inflammation in Hepatic Carcinogenesis

    • Principal Investigator
      UENO Shinichi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kagoshima University
  •  A new therapeutic concept for the treatment against sepsis using a functional material, 1,5-anhydrofructosePrincipal Investigator

    • Principal Investigator
      ABEYAMA Kazuhiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  加熱食品由来の化学反応中間体を用いた生体機能分子修飾:新規創薬法の開発Principal Investigator

    • Principal Investigator
      阿邉山 和浩
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Kagoshima University
  •  壊死性腸炎に対する経口ミコナゾール投与療法の有効性に関する研究

    • Principal Investigator
      高松 英夫
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatric surgery
    • Research Institution
      Kagoshima University
  •  Basic studies for development of inhibitor to target nuclear inflammatory cytokine related with sepsis

    • Principal Investigator
      ITO Yuji
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kagoshima University
  •  凝固外因系と自然免疫系のクロストークとシナージズム

    • Principal Investigator
      丸山 征郎
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kagoshima University
  •  Thrombomodulin : As a regulator of multiple mediators

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kagoshima University
  •  Evaluation of molecular mechanisms of dialysis related amyloidosis and the diagnosis method of early detection

    • Principal Investigator
      UCHIMURA Tomonori
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  Proteomic analysis of Crow-Fukase syndrome

    • Principal Investigator
      HASHIGUCHI Teruto
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  重症感染症における炎症誘導因子と致死性因子に対する同時性多重分子標的治療法の開発Principal Investigator

    • Principal Investigator
      阿邊山 和浩
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Newly development of functional low molecular therapeutics : Study of the pathomechanism of lethal multiple organ failurePrincipal Investigator

    • Principal Investigator
      ABEYAMA Kazuhiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Investigations on pathomechanism, diagnosis and treatment in bacterial shock-For preposal of new padadigm

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Investigation of the unknown factor over stimulating the VEGF prodution in Crow-Fukase syndrome.

    • Principal Investigator
      HASHIGUCHI Teruto
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  転写因子の分子生物学を基盤とした新しい癌・放射線治療法の開発Principal Investigator

    • Principal Investigator
      阿邊山 和浩
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      St. Marianna University School of Medicine
  •  "死のメディエーター":HMG-1の高感度測定と多臓器不全の診断法の確立

    • Principal Investigator
      MARUYAMA Ikurou
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University

All 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book Patent

  • [Book] 血管内皮細胞研究フロンティア2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Publisher
      血管内皮細胞による炎症・凝固系制御(炎症反応系と血液凝固系のクロストーク)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Gene expression profile during rat mammary carcinogenesis induced by 7,12- dimethylbenz[a]anthracene2009

    • Author(s)
      Souda M, Umekita Y, Abeyama K, Yoshida H
    • Journal Title

      Int J Cancer(IF : 4.555) (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Gene expression profile during rat mammary carcinogenesis induced by 7, 12-dimethylbenz[a]anthracene.2009

    • Author(s)
      Souda M, Umekita Y, Abeyama K, et al
    • Journal Title

      Int J Cancer. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Extracellular high mobility group box 1 protein is a coupling factor for hypoxia and detrimental inflammation in arthritis.2008

    • Author(s)
      Hamada T, Abeyama K, et. al.
    • Journal Title

      Arthritis Rheum.「掲載確定」 (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659200
  • [Journal Article] The role of water channel aquaporin 3 in the mechanism of TNF alpha-mediated proinflammatory events2008

    • Author(s)
      Tancharoen S, Matsuyama T, Abeyama K, Matsushita K. Kawahara K , Sangalungkarm V, Tokuda M, Hashiguchi T, Maruyama I, Izumi Y
    • Journal Title

      Implication in periodontal inflammation(IF : 3.643) 217(2)

      Pages: 338-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] The role of water channel aquaporin 3 in the mechanism of TNF-alpha-mediated proinflammatory events : Implication in periodontal inflammation.2008

    • Author(s)
      Tancharoen S, Matsuyama T, Abeyama K, et al
    • Journal Title

      J Cell Physiol. 217(2)

      Pages: 338-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis2008

    • Author(s)
      Hamada T, Torikai M, Kuwazuru A, Tanaka M, Horai N, Fukuda T, Yamada S, Nagayama S, Hashiguchi K, Sunahara N, Fukuzaki K, Nagata R, Komiya S, Maruyama I, Fukuda T, Abeyama K
    • Journal Title

      Arthritis Rheum(IF : 7.677) 58(9)

      Pages: 2675-2685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] A novel function of the receptor for advanced glycation end-products (RAGE) in association with tumorigenesis and tumor differentiation of HCC.2008

    • Author(s)
      Hiwatashi K, Abeyama K., et. al.
    • Journal Title

      Ann Surg Oncol. 15(3)

      Pages: 923-933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] A novel function of the receptor for advanced glycation end-products (RAGE) in association with tumorigenesis and tumor differentiation of HCC.2008

    • Author(s)
      Hiwatashi K, Abeyama K, et. al.
    • Journal Title

      Ann Surg Oncol. 15(3)

      Pages: 923-933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659200
  • [Journal Article] Extracellular high mobility group box chromosomal protein l is acoupling factor for hypoxia and inflammation in arthritis.2008

    • Author(s)
      Hamada T, Abeyama K., et al
    • Journal Title

      Arthritis Rheum. 58(9)

      Pages: 2675-2685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] A novel function of the receptor for advanced glycation end products (RAGE) in association with tumorigenesis and tumor differentiation of HCC2008

    • Author(s)
      Hiwatashi K, Ueno S, Abeyama K, Kubo F, Sakoda M, Maruyama I, Hamanoue M, Natsugoe S, Aikou T
    • Journal Title

      Ann Surg Oncol(IF : 3.917) 15(3)

      Pages: 923-933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Extracellular high mobility group box 1 protein is a coupling factor for hypoxia and detrimental inflammation in arthritis.2008

    • Author(s)
      Hamada T, Abeyama K., et. al.
    • Journal Title

      Arthritis Rheum.「掲載確定」 (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] High-mobility group box 1 protein promotes development of microvascular thrombosis in rats.2007

    • Author(s)
      Ito T., Abeyama K.et al.
    • Journal Title

      J Thromb Haemost. 5(1)

      Pages: 109-116

    • Data Source
      KAKENHI-PROJECT-18659200
  • [Journal Article] Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification2007

    • Author(s)
      Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H
    • Journal Title

      Mol Cell Biol(IF : 6.42) 27(16)

      Pages: 5650-5663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] High-mobility group box 1 protein promotes development of microvascular thrombosis in rats.2007

    • Author(s)
      Ito T., Abeyama K., et. al.
    • Journal Title

      J Thromb Haemost. 5(1)

      Pages: 109-116

    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] High-mobility group box 1 protein promotes development of microvascular thrombosis in rats2007

    • Author(s)
      Ito T, Kawahara K, Nakamura T, Yamada S, Nakamura T, Abeyama K, Hashiguchi T, Maruyama I
    • Journal Title

      J Thromb Haemost(IF : 5.947) 5(1)

      Pages: 109-1116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification.2007

    • Author(s)
      Taniguchi N, Abeyama K, et. al.
    • Journal Title

      Mol Cell Biol. 27(16)

      Pages: 5650-5663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659200
  • [Journal Article] Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification2007

    • Author(s)
      Taniguchi N, Abeyama K., et. al.
    • Journal Title

      Mol Cell Biol. 27(16)

      Pages: 5650-5663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] 炎症隔離分子としてのトロンボモジュリン2006

    • Author(s)
      阿辺山 和浩、丸山 征郎
    • Journal Title

      血管医学(メディカルレビュー社) 7(3)

      Pages: 19-25

    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Hydroxyapatite formed on/in agarose gel induces activation of blood coagulation and platelets aggregation2006

    • Author(s)
      Arimura SI, Abeyama K. et al.
    • Journal Title

      J Biomed Mater Res B Appl Biomater. 81B(2)

      Pages: 456-461

    • Data Source
      KAKENHI-PROJECT-18659200
  • [Journal Article] 炎症隔離分子としてのトロンボモジュリン2006

    • Author(s)
      阿辺山和浩、吉元 寧、丸山征郎
    • Journal Title

      血管医学((特集 : 血管炎のオムニバス)) vol. 7.No.3

      Pages: 19-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Hydroxyapatite formed on/in agarose gel induces activation of blood coagulation and platelets aggregation.2006

    • Author(s)
      Arimura SI., Abeyama K., et. al.
    • Journal Title

      J Biomed Mater Res B Appl Biomater. 81B(2)

      Pages: 456-461

    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein, a novel anti-inflammatory mechanism.2005

    • Author(s)
      Abeyama, K., Maruyama, I., et al.
    • Journal Title

      J Clin Invest 115・(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Activated protein C, a natural anticoagulant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K., Abeyama K., et al.
    • Journal Title

      Thromb.Res. 115(4)

      Pages: 319-325

    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation2005

    • Author(s)
      Yamaji, K., Abeyama, K., Hashiguchi, T.,Uchimura, T., Maruyama, I., et. al.
    • Journal Title

      Thromb Res 115(4)

      Pages: 319-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K, Wang Y, Liu Y, Abeyama K, Hashiguchi T, Uchimura T, Krishna Biswas K, Iwamoto H, Maruyama I.
    • Journal Title

      Thromb Res. 115(4)

      Pages: 319-325

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein,a novel anti-inflammatory mechanism2005

    • Author(s)
      Abeyama, K., Maruyama, I., et. al.
    • Journal Title

      J CIin Invest 115・5

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel anti-inflammatory mechanism.2005

    • Author(s)
      Abeyama, K., Maruyama, I., et al.
    • Journal Title

      J Clin Invest 115・5

      Pages: 1267-1274

    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K, Abeyama K, Hashiguchi T, Uchimura T, Maruyama I. et al.
    • Journal Title

      Thrombosis Research. 115(4)

      Pages: 319-325

    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Activated protein C, a natural anticoagulant properties and inhibits lipid peroxidation and advanced glycation end products formation2005

    • Author(s)
      Yamaji K., Abeyama K., et al.
    • Journal Title

      Thromb.Res. 115(4)

      Pages: 319-325

    • Data Source
      KAKENHI-PROJECT-16659493
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.2005

    • Author(s)
      Abeyama K., et al.
    • Journal Title

      J Clin Invest. 115(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K., Abeyama K., et al.
    • Journal Title

      Thromb Res. 115(4)

      Pages: 319-325

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.2005

    • Author(s)
      Abeyama K., et al.
    • Journal Title

      J Clin Invest 115(5)

      Pages: 1267-1274

    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] The N-Terminal Domain of Thrombomodulin Sequesters High Mobility Group-B1 Protein a Novel Anti-inflammatory Mechanism2005

    • Author(s)
      Abeyama K., et al.
    • Journal Title

      J Clin Invest. (In press)

    • Data Source
      KAKENHI-PROJECT-16659493
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.2005

    • Author(s)
      Abeyama K, Stern DM, Ito Y, Kawahara K, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I.
    • Journal Title

      J Clin Invest. 115(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.2005

    • Author(s)
      Abeyama K, Stern DM, Ito Y, Kawahara KI, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I.
    • Journal Title

      J Clin Invest. 115(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein, a novel anti-inflammatory mechanism.2005

    • Author(s)
      Abeyama, K., Maruyama, I., et al.
    • Journal Title

      J Clin Invest (In press)

    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein, a novel anti-inflammatory mechanism.2005

    • Author(s)
      Abeyama, K., Maruyama, I., et al.
    • Journal Title

      J Clin Invest 115・5

      Pages: 1267-1274

    • Data Source
      KAKENHI-PROJECT-17659294
  • [Journal Article] The N-Terminal Domain of Thrombomodulin Sequesters High Mobility Group-B1 Protein, a Novel Anti-inflammatory Mechanism.2005

    • Author(s)
      Abeyama K., et al.
    • Journal Title

      J Clin Invest. In press

    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation2005

    • Author(s)
      Yamaji K, Abeyama K, Hashiguchi T, Uchimura T, Maruyama I., et. al.
    • Journal Title

      Thrombosis Research 115(4)

      Pages: 319-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein a novel anti-inflammatory mechanism2005

    • Author(s)
      Abeyama, K., Maruyama, I., et. al.
    • Journal Title

      J Clin Invest(peer reviewed) 115(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] The anti-metastatic role of thrombomodulin expression in islet cell-derived tumors, and its diagnostic value.2004

    • Author(s)
      Iino S., Abeyama K., et al.
    • Journal Title

      Clin.Cancer Res. 10

      Pages: 6179-6188

    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] The anti-metastatic role of thrombomodulin expression in islet cell-derived tumors and its diagnostic value2004

    • Author(s)
      Iino S., Abeyama K., et al.
    • Journal Title

      Clin.Cancer Res. 10

      Pages: 6179-6188

    • Data Source
      KAKENHI-PROJECT-16659493
  • [Journal Article] 3章 血管内皮細胞による炎症・凝固系制御、-炎症反応系と血液凝固系のクロストーク-2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      血管内皮細胞研究フロンティア

      Pages: 21-23

    • Data Source
      KAKENHI-PROJECT-16659493
  • [Journal Article] (総説)病態生理 炎症とその制御システム2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      日本臨床 62(12)

      Pages: 2229-2235

    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] 病態生理 : 炎症とその制御システム2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      日本臨床 62(12)

      Pages: 2229-2235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] The antimetastatic role of thrombomodulin expression in islet cell-derived tumors and its diagnostic value.2004

    • Author(s)
      Iino S, Abeyama K, Kawahara K, Yamakuchi M, Hashiguchi T, Matsukita S, Yonezawa S, Taniguchi S, Nakata M, Takao S, Aikou T, Maruyama I.
    • Journal Title

      Clin Cancer Res. 10(18 pt.1)

      Pages: 6179-6188

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Thrombomodulin expression on Langerhans' islet : can endogenous 'anticoagulant on demand' overcome detrimental thrombotic complications in clinical islet transplantation?2004

    • Author(s)
      Iino S., Abeyama K., et al.
    • Journal Title

      J Thromb Haemost. 2(5)

      Pages: 833-834

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] The antimetastatic role of thrombomodulin expression in islet cell-derived tumors and its diagnostic value.2004

    • Author(s)
      Iino S., Abeyama K., et al.
    • Journal Title

      Clin Cancer Res. 10(18 pt.1)

      Pages: 6179-6188

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] 3章 血管内皮細胞による炎症・凝固系制御、-炎症反応系と血液凝固系のクロストーク-2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      血管内皮細胞研究フロンティア

      Pages: 21-23

    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Thrombomodulin expression on Langerhans' islet : can endogenous 'anticoagulant on demand' overcome detrimental thrombotic complications in clinical islet transplantation?2004

    • Author(s)
      Iino S, Abeyama K, Kawahara KI, Aikou T, Maruyama I.
    • Journal Title

      J Thromb Haemost. 2(5)

      Pages: 833-834

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] (総説)病態生理 炎症とその制御システム2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      日本臨床 62(12)

      Pages: 2229-2235

    • Data Source
      KAKENHI-PROJECT-16659493
  • [Journal Article] Inflammation and its regulatory system. (in Japanese)2004

    • Author(s)
      Abeyama K, Maruyama I.
    • Journal Title

      Nippon Rinsho 62(12)

      Pages: 2229-2235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Decreased total nitric oxide production in patients with duchenne muscular dystrophy.2004

    • Author(s)
      Kasai T., Abeyama K., et al.
    • Journal Title

      J Biomed Sci. 11(4)

      Pages: 534-537

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Regulatory cross-talk between inflammation and blood coagulation. (in Japanese)2004

    • Author(s)
      Abeyama K, Maruyama I.
    • Journal Title

      Kekkan-Naihisaibou kenkyuu Frontier

      Pages: 21-23

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Decreased total nitric oxide production in patients with duchenne muscular dystrophy.2004

    • Author(s)
      Kasai T, Abeyama K, Hashiguchi T, Fukunaga H, Osame M, Maruyama I.
    • Journal Title

      J Biomed Sci. 11(4)

      Pages: 534-537

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis.2003

    • Author(s)
      Biswas KK, Sarker KP, Abeyama K, Kawahara K, Iino S, Otsubo Y, Saigo K, Izumi H, Hashiguchi T, Yamakuchi M, Yamaji K, Endo R, Suzuki K, Imaizumi H, Maruyama I.
    • Journal Title

      Hepatology. 38(5)

      Pages: 1167-1177

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Patent] アディポネクチン産生増強剤2007

    • Inventor(s)
      阿邉山 和浩, ら
    • Industrial Property Rights Holder
      鹿児島大学・日本澱粉工業
    • Industrial Property Number
      2007-030146
    • Filing Date
      2007-02-09
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] カニクイザル (Cynomolgus Monkey) コラーゲン誘発性関節炎モデルにおける骨格筋の病理組織学的検討2009

    • Author(s)
      松田みゆき, 阿邊山 和浩, 他5名
    • Organizer
      第25回日本毒性病理学会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] 新しい理論に基づいたサイトプロテクションと疾病の予防・治療法開発2009

    • Author(s)
      阿辺山和浩
    • Organizer
      株式会社新日本科学、遺伝子解析ミーティング
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] "Arthritis-associated myopathy", a characteristic pathology of primate models.2009

    • Author(s)
      Horai N, Abeyama K., et al
    • Organizer
      Society of Toxicology 48th Annual Meeting & ToxExpo
    • Place of Presentation
      Baltimore USA
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] Arthritis- associated myopathy", a characteristic pathology of primate models2009

    • Author(s)
      Horai N, Abeyama K., et.al.
    • Organizer
      Society of Toxicology 48th Annual Meeting
    • Place of Presentation
      Baltimore USA
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] 血清薬理学的ファーマコゲノミクスを用いた生薬薬効の解析2007

    • Author(s)
      鈴東昌也、阿辺山和浩
    • Organizer
      トミーデジタルバイオロジー社主催Ingenuity pathway analysis ユーザーミーティング
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] Prophylactic Efficacy of Oral Miconazole Administration for Neonatal Intestinal Perforation, and Its Possible Mechanism.2007

    • Author(s)
      Torikai M, Abeyama K., et. al.
    • Organizer
      The 40th Annual Meeting of The Pacific Association of Paediatric Surgeons
    • Place of Presentation
      Queenstown, New Zealand
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] Therapeutic efficacy of oral miconazole administration for the treatment of neonatal intestinal disorders, and its possible mechanism2007

    • Author(s)
      Torikai M, Abeyama K, et.al.
    • Organizer
      The 40th Annual Scientifc Meeting of the Pacific Association of Paediatric Surgeons
    • Place of Presentation
      Queenstown, New Zealand
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] Sequential Changes in Oleic Acid-Induced Lung Injury in Dogs2007

    • Author(s)
      Nagaoka T, Abeyama K, et.al.
    • Organizer
      The Society of Toxicologic Pathology 26th Annual Meeting
    • Place of Presentation
      Puerto Rico
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] Prophylactic Efficacy of Oral Miconazole Administration for Neonatal Intestinal Perforation, and Its Possible Mechanism.2007

    • Author(s)
      Torikai M, Abeyama K, et. al.
    • Organizer
      The 40th Annual Meeting of The Pacific Association of Paediatric Surgeons
    • Place of Presentation
      Queenstown, New Zealand
    • Data Source
      KAKENHI-PROJECT-18659200
  • [Presentation] カニクイザルにおけるコンピュータ断層撮影法(CT)を用いた肺傷害の診断2006

    • Author(s)
      寳来直人、阿邉山和浩, 他8名
    • Organizer
      第33回日本トキシコロジー学会学術年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] Sequential Histologic Changes of Oleic Acid-Induced Lung Injury in Cynomolgus Monkeys2006

    • Author(s)
      Yang X, Abeyama K, et.al.
    • Organizer
      The Society of Toxicologic Pathology 25th Annual Meeting
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] Non-invasive Assessment of Pulmonary Disorder using Computed Tomography (CT)-Imaging in a Non-Human Primate2006

    • Author(s)
      Horai N, Abeyama K, et.al.
    • Organizer
      Society of Toxicology 45th Annual Meeting
    • Place of Presentation
      San Diego CA USA
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Presentation] カニクイザルにおけるコンピュータ断層撮影法(CT)を用いた肺傷害の診断2005

    • Author(s)
      坂東崇志、阿邉山和浩, 他7名
    • Organizer
      第3回日本予防医学会
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-18390481
  • 1.  MARUYAMA Ikurou (20082282)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 31 results
  • 2.  HASHIGUCHI Teruto (70250917)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 7 results
  • 3.  UCHIMURA Tomonori (20363616)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 4.  ARIMURA Kimiyoshi (20159510)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  ITO Takashi (20381171)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  ITO Yuji (60223195)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 7.  ABE Junichi (80128404)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 27 results
  • 8.  山口 宗一 (20325814)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  鵜島 雅子 (90336256)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  UENO Shinichi (40322317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  AIKOU Takashi (60117471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SAKODA Masahiko (40418851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NAKAJIMA Toshihiro (90260752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SUGIMURA Kazuhisa (80127240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  HASHIGUCHI Shuhei (40295275)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  高松 英夫 (50142427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  田原 博幸 (70236719)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  加治 建 (50315420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  下野 隆一 (60404521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  林田 良啓 (80305135)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  川上 雅之 (70336345)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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