INUKAI Takeshi 犬飼岳史

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Inukai Takeshi 犬飼岳史

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Researcher Number	30293450
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 山梨大学, 大学院総合研究部, 教授 2017: 山梨大学, 大学院総合研究部, 准教授 2014 – 2016: 山梨大学, 総合研究部, 准教授 2012 – 2013: 山梨大学, 医学工学総合研究部, 准教授 2010 – 2011: 山梨大学, 大学院・医学工学総合研究部, 准教授 … More 2007 – 2009: University of Yamanashi, Hospital, Assistant Professor 2008: University of Yamanashi, 医学部・附属病院, 講師 2006: University of Yamanashi, Department of Research Interdisciplinary Graduate School of Medicine and Engineering, Research Associate, 大学院医学工学総合研究部, 助手 2003 – 2005: University of Yamanashi, Interdisciplinary Graduate School of medicine and Engineering, Research Associate, 大学院・医学工学総合研究部, 助手 2002: 山梨大学, 医学部, 助手 1998 – 2001: 山梨医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pediatrics / Biological Sciences / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Pediatrics
Keywords	Principal Investigator 白血病 / アポトーシス / 細胞傷害因子 / TRAIL / 転写因子 / 移植片対白血病効果 / 細胞周期 / ゲノム編集 / 薬剤感受性 / 急性リンパ性白血病 … More / 細胞障害因子 / 個別化治療 / 難治性 / apoptosis / leukemia / 11q23転座型白血病 / 小胞体ストレス / 造血幹細胞移植 / 細胞死 / 17;19転座 / GVL効果 / 移植片対白血病(GVL)効果 / Philadelphia染色体陽性白血病 / E2A-HLF / 造血幹細胞 / サイトカイン / 造血系幹細胞 / ゲノム編集技術 / ゲノム解析 / ゲノム情報 / がんゲノム / 薬剤耐性 / 遺伝子多型 / 一塩基多型 / 遺伝子変異 / 化学療法 / Ph1-positive leukemia / T-cell leukemia / 11q23 rearranged leukemia / GVL effect / endoplasmic reticulum-stress / cytotoxic ligands / Fas / 同種造血幹細胞移植 / Ph1陽性白血病 / T細胞型急性リンパ性白血病 / TNF-family ligands / GVL-effect / cytotoxic T-lymphocytes / allo-SCT / T細胞性急性リンパ性白血病 / FasL / 細胞傷害性Tリンパ球 / 同種骨髄移植 / 小児難治性白血病 / BCR-ABL / Slug遺伝子 / 17 ; 19転座 / DR5受容体 / DR4 / DR3 / TWEAK / 難治性小児白血病 / プロモーター / SLUG遺伝子 / 受容体 / 細胞周期抑制 / メチル化 / 11q23転座 / 癌抑制遺伝子 … More Except Principal Investigator apoptosis / アポトーシス / ALL / PKC412 / 11q23転座 / 白血病 / 11q23転座型白血病 / FLT3 / 11q23 translocation / CD33 / cell cycle arrest / 急性リンパ性白血病 / childhood leukemia / 細胞周期停止 / HDAC inhibitor / Philadelphia染色体陽性白血病 / 細胞傷害因子 / 細胞周期 / 難治性小児白血病 / ヒアルロン酸 / ネクローシス / 細胞死 / CD44 / 超低分子量ヒアルロン酸 / 11q23 tralslocations / FLT3 ligand / FLT3リガンド / childhood ALL / anti-FLT3 agent / 小児急性白血病 / Bim / STAT5 / 白血病細胞株 / 細胞回転停止 / 小児ALL / FLT3阻害剤 / LMO2 / t(17;19) / cytotoxic ligand / FLT-3遺伝子 / BCR-ABL / Imatinib / 分子標的療法 / E2A-HLF / LMO2遺伝子 / 難治性白血病 / LM02 / 17;19転座 / 小児白血病 / differentiation / Histone deacetylase inhibitor / acute lymphoblastic leukemia / 分化誘導 / 脱メチル化剤 / B前駆型リンパ性白血病 / ヒストン脱アセチル化阻害剤 / Cell cycle / p16 gene / Rb gene / 細胞回転 / p16遺伝子 / Rb遺伝子 / GVL effect / all-SCT / TNF-family ligands / cytokine / cell cycle / chemo-resistance / 11q23転座型急性リンパ性白血病 / philadelphia染色体陽性白血病 / 移植片対白血病(GVL)効果 / 耐性機序 / STI571 / 造血因子 / T細胞型急性リンパ性白血病 / Philadelhia染色体陽性白血病 / GVL効果 / 同種造血幹細胞移植 / サイトカイン / 薬剤耐性 / proliferation / physiologically active substances / leukemic cells / 増殖 / 生理活性物質 / 白血病細胞 / Cytokine / Transcriptin factor / Translaocation / Chemotherapy / Apoptosis / Leukemia / 多剤耐性 / G-CSF / ステロイド剤 / 化学療法 / 小児急性リンパ性白血病 / 17;19転座型白血病 / 9;22転座型白血病 / プロモーター / 造血因子受容体 / 転写因子 / 転座型白血病 / 難治性小児急性白血病 Less

難治性急性リンパ性白血病に対するプレシジョン・メディシンを目指した多分野融合研究Principal Investigator
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  University of Yamanashi
Integrated study aiming at development of precision medicine for poor prognostic acute lymphoblastic leukemiaPrincipal Investigator
- Principal Investigator
  
  Inukai Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  University of Yamanashi
Establishment of ALL cell line bank to identify genetic factors involving in drug-sensitivity for future precision medicinePrincipal Investigator
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
CD44-targetted therapy for CD44-high expressing tumors by ultra-low-molecular-weight hyaluronan
- Principal Investigator
  
  SUGITA Kanji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Research for clinical application of cytotoxic ligands for graft-versus-leukemia effect against childhood leukemiaPrincipal Investigator
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Clinical significance of cytotoxic factor-mediated graft-versus-leukemia effect against high-risk childhood leukemiaPrincipal Investigator
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Involvement of Slug transcription factor, a human homolog of ces-1 of C. elegans, in the regulation of apoptotic cell death of leukemia cellsPrincipal Investigator
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
細胞傷害因子の移植片対白血病効果における意義と臨床応用に向けた研究Principal Investigator
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Yamanashi
Analysis of the FLT3/FLT3 ligand system in ALL with 11q23 translocations
- Principal Investigator
  
  SUGITA Kanji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Establishment of new-therapy and analysis of mechanisms for resistance to apoptosis in poor-prognostic childhood leukemia
- Principal Investigator
  
  NAKAZAWA Shinpei
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Anti-leukemic activity of cytotoxic ligands against poor-prognostic childhood leukemiaPrincipal Investigator
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
anti-leukemic activity of FLT3 inhibitor on childhood acute lymphoblastic leukemia with 11q23 translocation
- Principal Investigator
  
  SUGITA Kanji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Histone acetylation in childhood high-risk acute leukemia
- Principal Investigator
  
  GOI Kumiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Anti-leukemic activities of TNF-family ligands in childhood poor-prognostic leukemiaPrincipal Investigator
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
  山梨医科大学
Analysis of tumor supressor genes p16 and Rb in childhood acute lymphoblastic leukemia
- Principal Investigator
  
  SUGITA Kanji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
  山梨医科大学
造血幹細胞のアポトーシス及び細胞周期の転写因子による制御機構の解明Principal Investigator
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  山梨医科大学
Resistance to apoptosis in childhood poor-prognostic leukemia
- Principal Investigator
  
  NAKAZAWA Shinpei
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
  山梨医科大学
造血幹細胞のアポトーシス及び細胞周期の転写因子による制御機構の解明Principal Investigator
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  山梨医科大学
小児急性白血病における細胞傷害性因子の解析と臨床的意義Principal Investigator
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  山梨医科大学
造血幹細胞は、アポトーシス及び細胞周期の転写因子による制御機構の解明Principal Investigator
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  山梨医科大学
造血幹細胞のアポトーシス及び細胞周期の転写因子による制御機構の解明Principal Investigator
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  山梨医科大学
11q23転座型における癌抑制遺伝子p16のメチル化による不活化の検討Principal Investigator
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  山梨医科大学
The pivotal role of apoptosis in leukemogenesis and chemo-sensitivity in childhood leukemias.
- Principal Investigator
  
  NAKAZAWA Shinpei
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pediatrics
- Research Institution
  Yamanashi Medical University
Analysis of biologically active substances in volved in growth regulation of leukemia cells
- Principal Investigator
  
  SUGITA Kanji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yamanashi Medical University

[Book] ゲノム編集技術を応用した製品開発とその実用化　第5章8節「ゲノム編集技術を用いた薬剤耐性をもつ白血病細胞株の樹立と医薬品評価への応用」ゲノム編集技術を応用した製品開発とその実用化　第5章8節2021
- Author(s)
  玉井望雅, 犬飼岳史
- Total Pages
  12
- Publisher
  技術情報協会
- ISBN
  9784861048272
- Data Source
  KAKENHI-PROJECT-19H03615
[Book] 免疫症候群II（急性リンパ性白血病）2016
- Author(s)
  犬飼　岳史
- Total Pages
  859
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-15K09645
[Book] 小児血液・腫瘍学 (がんの細胞生物学）2015
- Author(s)
  犬飼　岳史
- Total Pages
  585
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-15K09645
[Book] 別冊・医学のあゆみ血液疾患-state of arts Ver.32005
- Author(s)
  坂田洋一, 犬飼岳史ほか
- Total Pages
  797
- Publisher
  医歯薬出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ueda Atsushi、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Journal Title
  
  Blood
  
  Volume: 143 Issue: 7 Pages: 604-618
- DOI
  10.1182/blood.2023020857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-21K08393, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-23K24298
[Journal Article] Application of prime editing system to introduce P53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line2024
- Author(s)
  Nguyen Thao、Aida Tomomi、Iijima‐Yamashita Yuka、Tamai Minori、Nagamachi Akiko、Kagami Keiko、Komatsu Chiaki、Kasai Shin、Akahane Koshi、Goi Kumiko、Inaba Toshiya、Sanada Masashi、Inukai Takeshi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 0-0
- DOI
  10.1111/cas.16162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08395, KAKENHI-PROJECT-23K24298
[Journal Article] Rare TCF3 variants associated with pediatric B cell acute lymphoblastic leukemia2023
- Author(s)
 Miyamoto Satoshi、Urayama Kevin Y.、Arakawa Yuki、Koh Katsuyoshi、Takahashi Hiroyuki、Keino Dai、Toyama Daisuke、Takita Junko、Tomizawa Daisuke、Morio Tomohiro、Sekinaka Yujin、Manabe Atsushi、Takagi Masatoshi
- Journal Title
 
 Pediatric Hematology and Oncology
 
 Volume: - Issue: 1 Pages: 1-7
- DOI
 10.1080/08880018.2023.2201302
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20K16942, KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-23K24298
[Journal Article] TCF3::HLF陽性白血病の難治性病態とその克服　17;19転座陽性急性リンパ性白血病の化学療法耐性とTRAIL高感受性2023
- Author(s)
  犬飼岳史
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 60 Pages: 207-213
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Generation of Philadelphia chromosome in human leukemia by DNA breaks on the BCR and ABL1 genes using CRISPR/Cas9 system.2023
- Author(s)
  Tamai M, Fujisawa S, Nguyen Thao TT, Komatsu C, Kagami K, Kamimoto K, Omachi K, Kasai S, Harama D, Watanabe A, Akahane K, Goi K, Naka K, Kaname T, Teshima T, and Inukai T
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: 30 Issue: 1 Pages: 38-50
- DOI
  10.1038/s41417-022-00522-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19353, KAKENHI-PROJECT-21K15528, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-23K24298
[Journal Article] Genome-wide assessment of genetic risk loci for childhood acute lymphoblastic leukemia in Japanese patients2023
- Author(s)
  Hangai Mayumi、Kawaguchi Takahisa、Takagi Masatoshi、Inukai Takeshi、Manabe Atsushi、Urayama Kevin Y, et al.
- Journal Title
  
  Haematologica
  
  Volume: 109 Pages: 1247-1252
- DOI
  10.3324/haematol.2023.282914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells2023
- Author(s)
  Hiroki Haruka、Ishii Yuko、Piao Jinhua、Namikawa Yui、Masutani Mitsuko、Honda Hiroaki、Akahane Koshi、Inukai Takeshi、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 7588-7588
- DOI
  10.1038/s41598-023-33852-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24298, KAKENHI-PROJECT-23K27442
[Journal Article] CRISPR/Cas9-Mediated Induction of Relapse-Specific NT5C2 and PRPS1 Mutations Confers Thiopurine Resistance as a Relapsed Lymphoid Leukemia Model2023
- Author(s)
  Nguyen Thao Thu Thi、Tanaka Yoichi、Sanada Masashi、Hosaka Masumi、Tamai Minori、Kagami Keiko、Komatsu Chiaki、Somazu Shinpei、Harama Daisuke、Kasai Shin、Watanabe Atsushi、Akahane Koushi、Goi Kumiko、Inukai Takeshi
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 103 Issue: 4 Pages: 199-210
- DOI
  10.1124/molpharm.122.000546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Utility of ASNS gene methylation evaluated with the HPLC method as a pharmacogenomic biomarker to predict asparaginase sensitivity in BCP-ALL2023
- Author(s)
  Watanabe Atsushi、Miyake Kunio、Yamada Yuriko、Sunamura Ei-Ichiro、Yotani Takuya、Kagami Keiko、Kasai Shin、Tamai Minori、Harama Daisuke、Akahane Koshi、Goi Kumiko、Sakaguchi Kimiyoshi、Goto Hiroaki、Kitahara Shinichiro、Inukai Takeshi
- Journal Title
  
  Epigenetics
  
  Volume: 18 Issue: 1 Pages: 2268814-2268814
- DOI
  10.1080/15592294.2023.2268814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Low NUDT15 expression levels due to biallelic NUDT15 variants and 6‐mercaptopurine intolerance2022
- Author(s)
  Yoshida M, Brown SA, Moriyama T, Nishii R, Tsujimoto SI, Yamada Y, Yoshida K, Shirai R, Osumi T, Utano T, Fukano R, Kudo K, Sakaguchi K, Arakawa Y, Koh K, Sekiguchi M, Sekimizu M, Miyamura T, Ishida H, Inukai T, Tomizawa D, Kiyokawa N, Kato M, Yang JJ.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 199 Issue: 2 Pages: 270-276
- DOI
  10.1111/bjh.18375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Introduction of the T315I gatekeeper mutation of BCR/ABL1 into a Philadelphia chromosome-positive lymphoid leukemia cell line using the CRISPR/Cas9 system2022
- Author(s)
  Nguyen Thao T. T.、Tamai Minori、Harama Daisuke、Kagami Keiko、Kasai Shin、Watanabe Atsushi、Akahane Koshi、Goi Kumiko、Inukai Takeshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 116 Issue: 4 Pages: 534-543
- DOI
  10.1007/s12185-022-03369-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL2022
- Author(s)
 Akahane Koshi、Kimura Shunsuke、Miyake Kunio、Watanabe Atsushi、Kagami Keiko、Yoshimura Kentaro、Shinohara Tamao、Harama Daisuke、Kasai Shin、Goi Kumiko、Kawai Tomoko、Hata Kenichiro、Kiyokawa Nobutaka、Koh Katsuyoshi、他7名
- Journal Title
 
 Blood Advances
 
 Volume: 6 Issue: 1 Pages: 212-224
- DOI
 10.1182/bloodadvances.2021004271
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-19K07728, KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21K19405
[Journal Article] Synergistic effect of combined PI3 kinase inhibitor and PARP inhibitor treatment on BCR/ABL1-positive acute lymphoblastic leukemia cells2022
- Author(s)
  Hiroki Haruka、Akahane Koshi、Inukai Takeshi、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 5 Pages: 748-758
- DOI
  10.1007/s12185-022-03520-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] BCL6 inhibition ameliorates resistance to ruxolitinib in CRLF2-rearranged acute lymphoblastic leukemia2022
- Author(s)
 Tsuzuki Shinobu、Yasuda Takahiko、Goto Hiroaki、Maeda Naoko、Akahane Koshi、Inukai Takeshi、Yamamoto Hideyuki、Karnan Sivasundaram、Ota Akinobu、Hyodo Toshinori、Konishi Hiroyuki、Hosokawa Yoshitaka、Kiyoi Hitoshi、Hayakawa Fumihiko
- Journal Title
 
 Haematologica
 
 Volume: 108 Issue: 2 Pages: 394-408
- DOI
 10.3324/haematol.2022.280879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-21K08426, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-23K24118, KAKENHI-PROJECT-23K24298, KAKENHI-PROJECT-23K24362
[Journal Article] Successful treatment of intractable gastrointestinal tract graft-vs-host disease with oral beclomethasone dipropionate in pediatric and young adult patients2022
- Author(s)
  Akahane Koshi、Watanabe Atsushi、Somazu Shinpei、Harama Daisuke、Shinohara Tamao、Kasai Shin、Oshiro Hiroko、Goi Kumiko、Hasuda Norio、Ozawa Chihiro、Sugita Kanji、Inukai Takeshi
- Journal Title
  
  Medicine
  
  Volume: 101 Issue: 11
- DOI
  10.1097/md.0000000000029054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Prominence of NUDT15 genetic variation associated with 6‐mercaptopurine tolerance in a genome‐wide association study of Japanese children with acute lymphoblastic leukaemia2022
- Author(s)
  Tanaka Yoichi、Urayama Kevin Y.、Mori Makiko、Arakawa Yuki、Hasegawa Daisuke、Noguchi Yasushi、Yanagimachi Masakatsu、Keino Dai、Ota Setsuo、Akahane Koshi、Inukai Takeshi、Hangai Mayumi、Kawaguchi Takahisa、Takagi Masatoshi、Koh Katsuyoshi、Matsuda Fumihiko、Manabe Atsushi
- Journal Title
  
  British Journal of Haematology
  
  Volume: 199 Issue: 2 Pages: 260-269
- DOI
  10.1111/bjh.18405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] CN470 is a BET/CBP/p300 multi-bromodomain inhibitor and has an anti-tumor activity against MLL-rearranged acute lymphoblastic leukemia2022
- Author(s)
  Imayoshi Natsuki、Yoshioka Makoto、Tanaka Kuniaki、Yang Shyh-Ming、Akahane Koshi、Toda Yuki、Hosogi Shigekuni、Inukai Takeshi、Okada Seiji、Maloney David J.、Nakahata Tatsutoshi、Takita Junko、Kato Itaru、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 49-54
- DOI
  10.1016/j.bbrc.2021.12.078
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20J22374, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-20K17388, KAKENHI-PROJECT-23K24298
[Journal Article] Genome-wide CRISPR-Cas9 screen identifies rationally designed combination therapies for CRLF2-rearranged Ph-like ALL2022
- Author(s)
  Sasaki Kensuke、Yamauchi Takuji、Semba Yuichiro、Nogami Jumpei、Imanaga Hiroshi、Terasaki Tatsuya、Nakao Fumihiko、Akahane Koshi、Inukai Takeshi、Verhoeyen Els、Akashi Koichi、Maeda Takahiro
- Journal Title
  
  Blood
  
  Volume: 139 Issue: 5 Pages: 748-760
- DOI
  10.1182/blood.2021012976
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-21H04827
[Journal Article] Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia2022
- Author(s)
  Tamai Minori、Kasai Shin、Akahane Koshi、Thu Thao Nguyen、Kagami Keiko、Komatsu Chiaki、Abe Masako、Watanabe Atsushi、Goi Kumiko、Miyake Kunio、Inaba Toshiya、Takita Junko、Goto Hiroaki、Minegishi Masayoshi、Iwamoto Shotaro、Sugita Kanji、Inukai Takeshi
- Journal Title
  
  The Journal of Steroid Biochemistry and Molecular Biology
  
  Volume: 218 Pages: 106068-106068
- DOI
  10.1016/j.jsbmb.2022.106068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-21H02948, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-23K24298
[Journal Article] Epigenetic Modification of Death Receptor Genes for TRAIL and TRAIL Resistance in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia2021
- Author(s)
  Watanabe Atsushi、Miyake Kunio、Akahane Koshi、Goi Kumiko、Kagami Keiko、Yagita Hideo、Inukai Takeshi
- Journal Title
  
  Genes
  
  Volume: 12 Issue: 6 Pages: 864-864
- DOI
  10.3390/genes12060864
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20H03928
[Journal Article] Heme activates platelets and exacerbates rhabdomyolysis-induced acute kidney injury via CLEC-2 and GPVI/FcRγ2021
- Author(s)
  S. Oishi, N. Tsukiji, S. Otake, N. Oishi, T. Sasaki, T. Shirai, Y. Yoshikawa, K. Takano, H. Shinmori, T. Inukai, T. Kondo, K. Suzuki-Inoue
- Journal Title
  
  blood advances
  
  Volume: 5 Issue: 7 Pages: 2017-2026
- DOI
  10.1182/bloodadvances.2020001698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K04724, KAKENHI-PROJECT-19K16554, KAKENHI-PROJECT-19K08834, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20K08729, KAKENHI-PROJECT-21K04674, KAKENHI-PROJECT-21K06883
[Journal Article] IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform2021
- Author(s)
  Harama Daisuke、Yahata Takashi、Kagami Keiko、Abe Masako、Ando Norie、Kasai Shin、Tamai Minori、Akahane Koshi、Inukai Takeshi、Kiyokawa Nobutaka、Ibrahim Abd Aziz、Ando Kiyoshi、Sugita Kanji
- Journal Title
  
  Cell Death Discovery
  
  Volume: 7 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41420-021-00523-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K14702, KAKENHI-PROJECT-23K21386
[Journal Article] NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells2021
- Author(s)
  Somazu S, Tanaka Y, Tamai M, Watanabe A, Kagami K, Abe M, Harama D, Shinohara T, Akahane K, Goi K, Sugita K, Moriyama T, Yang J, Goto H, Minegishi M, Iwamoto S,?Takita J, Inukai T
- Journal Title
  
  J Cell Mol Med
  
  Volume: 25 Issue: 22 Pages: 10521-10533
- DOI
  10.1111/jcmm.16981
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-21K19405
[Journal Article] KIR3DL1 Allotype-Dependent Modulation of NK Cell Immunity against Chronic Myeloid Leukemia2021
- Author(s)
  Izumi Kiyotaka、Shindo Takero、Ngo Huong Thi、Nakayama-Hosoya Kaori、Akahane Koshi、Tamai Minori、Nguyen Thao T. T.、Kawana-Tachikawa Ai、Inukai Takeshi、Takaori-Kondo Akifumi
- Journal Title
  
  ImmunoHorizons
  
  Volume: 5 Issue: 8 Pages: 687-702
- DOI
  10.4049/immunohorizons.2100054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08812, KAKENHI-PROJECT-19H03615
[Journal Article] Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells2021
- Author(s)
  Malyukova Alena、Ujvari Dorina、Yektaei-Karin Elham、Zovko Ana、Madapura Harsha S.、Keszei Marton、Nagy Noemi、Lotfi Kourosh、Bj?rn Niclas、Wallvik Jonas、Tamai Minori、Nguyen Thao T. T.、Akahane Koshi、Inukai Takeshi、Stenke Leif、Salamon Daniel
- Journal Title
  
  Cell Death & Disease
  
  Volume: 12 Issue: 10
- DOI
  10.1038/s41419-021-04154-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia.2020
- Author(s)
  Kumar R, Pereira RS, Zanetti C, Minciacchi VR, Merten M, Meister M, Niemann J, Dietz MS, Russel N, Schnutgen F, Tamai M, Akahane K, Inukai T, Oellerich T, Kvasnicka HM, Pfeifer H, Nicolini FE, Heilemann M, Van Etten RA, Krause DS.
- Journal Title
  
  Leukemia
  
  Volume: 34 Issue: 8 Pages: 2087-2101
- DOI
  10.1038/s41375-020-0866-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL2020
- Author(s)
  Atsushi Watanabe, Kunio Miyake, Jessica Nordlund, Ann-Christine Syvanen, Louise van der Weyden, Hiroaki Honda, Norimasa Yamasaki, Akiko Nagamachi, Toshiya Inaba, Tomokatsu Ikawa, Kevin Y Urayama, Nobutaka Kiyokawa, Akira Ohara, Shunsuke Kimura, Yasuo Kubota, Junko Takita, Hiroaki Goto, Kimiyoshi Sakaguchi, et al.
- Journal Title
  
  Blood
  
  Volume: 136 Issue: 20 Pages: 2319-2333
- DOI
  10.1182/blood.2019004090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08318, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19KK0222, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-18K08357, KAKENHI-PROJECT-20H00528
[Journal Article] Assessment of MGMT methylation status using high-performance liquid chromatography in newly diagnosed glioblastoma2020
- Author(s)
  Hanihara M, Miyake K, Watanabe A, Yamada Y, Oishi N, Kawataki T, Inukai T, Kondo T, Kinouchi H.
- Journal Title
  
  Clin Epigenetics
  
  Volume: 12(1) Issue: 1 Pages: 174-174
- DOI
  10.1186/s13148-020-00968-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-19K16554
[Journal Article] High prevalence of MEF2D fusion in human B-cell precursor acute lymphoblastic leukemia cell lines.2020
- Author(s)
  Akahane K, Yasuda T, Tsuzuki S, Hayakawa F, Kiyokawa N, Somazu S, Watanabe A, Kagami K, Abe M, Harama D, Goi K, Kawazu M, Kojima S, Imamura T, Goto H, Iwamoto S, Minegishi M, Abe M, Hojo H, Inaba T, Mano H, Sugita K, Inukai T.
- Journal Title
  
  Hematol Oncol.
  
  Volume: 38 Issue: 4 Pages: 614-617
- DOI
  10.1002/hon.2762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615
[Journal Article] Aurora B kinase as a therapeutic target in acute lymphoblastic leukemia.2020
- Author(s)
  Goto H, Yoshino Y, Ito M, Nagai J, Kumamoto T, Inukai T, Sakurai Y, Miyagawa N, Keino D, Yokosuka T, Iwasaki F, Hamanoue S, Shiomi M, Goto S.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 85 Issue: 4 Pages: 773-783
- DOI
  10.1007/s00280-020-04045-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia2020
- Author(s)
  Ueno H、Yoshida K、et al, 、Sanada M
- Journal Title
  
  Blood Advances
  
  Volume: 4 Issue: 20 Pages: 5165-5173
- DOI
  10.1182/bloodadvances.2019001307
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08723, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K15694, KAKENHI-PROJECT-20H00528
[Journal Article] Association of relapse-linked ARID5B single nucleotide polymorphisms with drug resistance in B-cell precursor acute lymphoblastic leukemia cell lines.2020
- Author(s)
  Tamai M, Huang M, Kagami K, Abe M, Somazu S, Shinohara T, Harama D, Watanabe A, Akahane K, Goi K, Sugita K, Goto H, Minegishi M, Iwamoto S, Inukai T.
- Journal Title
  
  Cancer Cell Int
  
  Volume: 20 Issue: 1 Pages: 434-434
- DOI
  10.1186/s12935-020-01524-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Impact of immunophenotypic characteristics on genetic subgrouping in childhood acute lymphoblastic leukemia: Tokyo Children’s Cancer Study Group ( TCCSG ) study L04 ‐162020
- Author(s)
  Ohki Kentaro, Takahashi Hiroyuki, Fukushima Takashi, Kiyokawa Nobutaka. et al.
- Journal Title
  
  Genes, Chromosomes and Cancer
  
  Volume: － Issue: 10 Pages: 551-561
- DOI
  10.1002/gcc.22858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15694, KAKENHI-PROJECT-20K08744, KAKENHI-PROJECT-19H03615
[Journal Article] Inherited genetic variants associated with glucocorticoid sensitivity in leukaemia cells.2020
- Author(s)
  Shinohara T, Urayama KY, Watanabe A, Akahane K, Goi K, Huang M, Kagami K, Abe M, Sugita K, Okada Y, Goto H, Minegishi M, Iwamoto S, Inukai T.
- Journal Title
  
  J Cell Mol Med
  
  Volume: 24 Issue: 22 Pages: 12920-12932
- DOI
  10.1111/jcmm.15882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Successful hematopoietic stem cell transplantation from an HLA-mismatched parent for engraftment failure after unrelated cord blood transplantation in patients with juvenile myelomonocytic leukemia: Report of two cases.2019
- Author(s)
  Akahane K, Watanabe A, Furuichi Y, Somazu S, Oshiro H, Goi K, Sakashita K, Muramatsu H, Hama A, Takahashi Y, Koike K, Kojima S, Sugita K, Inukai T.
- Journal Title
  
  Pediatr Transplant.
  
  Volume: 3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] High ENT1 and DCK gene expression levels are a potential biomarker to predict favorable response to nelarabine therapy in T-cell acute lymphoblastic leukemia.2019
- Author(s)
  Akahane K, Murakami Y, Kagami K, Abe M, Harama D, Shinohara T, Watanabe A, Goi K, Nishi R, Yamauchi T, Kimura S, Takita J, Look AT, Minegishi M, Sugita K, Inukai T.
- Journal Title
  
  Hematol Oncol.
  
  Volume: 37 Issue: 4 Pages: 516-519
- DOI
  10.1002/hon.2654
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07294, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K19467
[Journal Article] Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to multiagents in induction therapy.2019
- Author(s)
  Watanabe A, Inukai T, Kagami K, Abe M, Takagi M, Fukushima T, Fukushima H, Nanmoku T, Terui K, Ito T, Toki T, Ito E, Fujimura J, Goto H, Endo M, Look T, Kamps M, Minegishi M, Takita J, Inaba T, Takahashi H, Ohara A, Harama D, Shinohara T, Somazu S, Oshiro H, Akahane K, Goi K, Sugita K.
- Journal Title
  
  Cancer Med.
  
  Volume: 7 Issue: 11 Pages: 5274-5288
- DOI
  10.1002/cam4.2356
- NAID
  120007159553
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K19467
[Journal Article] Nationwide survey of pediatric hypodiploid acute lymphoblastic leukemia in Japan2019
- Author(s)
  Ishimaru Sae、Okamoto Yasuhiro、Imai Chihaya、Sakaguchi Hirotoshi、Taki Tomohiko、Hasegawa Daisuke、Cho Yuko、Kakuda Harumi、Sano Hideki、Manabe Atsushi、Imamura Toshihiko、Kato Motohiro、Arakawa Yuki、Shimonodan Hidemi、Sato Atsushi、Suenobu Souichi、et al.
- Journal Title
  
  Pediatrics International
  
  Volume: 61 Issue: 11 Pages: 1103-1108
- DOI
  10.1111/ped.14006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07822, KAKENHI-PROJECT-18K08335, KAKENHI-PROJECT-19K08317, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-17K10117, KAKENHI-PROJECT-17K10129
[Journal Article] Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese2018
- Author(s)
  Urayama Kevin Y.、Takagi Masatoshi、Kawaguchi Takahisa、Matsuo Keitaro、Tanaka Yoichi、Ayukawa Yoko、Arakawa Yuki、Hasegawa Daisuke、Yuza Yuki、Kaneko Takashi、Noguchi Yasushi、Taneyama Yuichi、Ota Setsuo、Inukai Takeshi、Yanagimachi Masakatsu、Keino Dai、Koike Kazutoshi、Toyama Daisuke、Inazawa Johji 他16名
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 789-789
- DOI
  10.1038/s41598-017-19127-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-15K09645, KAKENHI-PROJECT-16K14630, KAKENHI-PROJECT-17K10129, KAKENHI-PROJECT-15K18932
[Journal Article] Splicing variant profiles and single nucleotide polymorphisms of the glucocorticoid receptor gene in relation to glucocorticoid sensitivity of B-cell precursor acute lymphoblastic leukaemia.2018
- Author(s)
  Huang M, Inukai T, Kagami K, Abe M, Shinohara T, Watanabe A, Somazu S, Oshiro H, Goi K, Goto H, Minegishi M, Iwamoto S, Urayama KY, Sugita K.
- Journal Title
  
  Hematol Oncol.
  
  Volume: 36(1) Issue: 1 Pages: 245-251
- DOI
  10.1002/hon.2471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09645
[Journal Article] Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF-positive leukemic cells.2017
- Author(s)
  Piao J, Takai S, Kamiya T, Inukai T, Sugita K, Ohyashiki K, Delia D, Masutani M, Mizutani S, Takagi M.
- Journal Title
  
  Cancer Lett
  
  Volume: 386 Pages: 131-140
- DOI
  10.1016/j.canlet.2016.11.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09645
[Journal Article] Long-term outcome of six-month maintenance chemotherapy for acute lymphoblastic leukemia in children.2017
- Author(s)
  Kato M, Ishimaru S, Seki M, Yoshida K, Shiraishi Y, Chiba K, Kakiuchi N, Sato Y, Ueno H, Tanaka H, Inukai T, Tomizawa D, Hasegawa D, Osumi T, Arakawa Y, Aoki T, Okuya M, Kaizu K, Kato K, Taneyama Y, Goto H, Taki T, Takagi M, Sanada M, Koh K, Takita J, Miyano S, Ogawa S, Ohara A, Tsuchida M, Manabe A.
- Journal Title
  
  Leukemia.
  
  Volume: 31 Issue: 3 Pages: 580-584
- DOI
  10.1038/leu.2016.274
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293242, KAKENHI-PROJECT-26713037, KAKENHI-PROJECT-15K09486, KAKENHI-PROJECT-15K09645, KAKENHI-PLANNED-15H05909
[Journal Article] 急性リンパ性白血病の薬剤耐性機序2017
- Author(s)
  犬飼岳史
- Journal Title
  
  臨床血液
  
  Volume: 57 Pages: 2011-2028
- NAID
  130005250015
- Data Source
  KAKENHI-PROJECT-15K09645
[Journal Article] TGFβ1 synergizes with FLT3 ligand to induce chemoresistant quiescence in acute lymphoblastic leukemia with MLL gene rearrangements.2017
- Author(s)
  Tamai M, Furuichi Y, Kasai S, Ando N, Harama D, Goi K, Inukai T, Kagami K, Abe M, Ichikawa H, Sugita K.
- Journal Title
  
  Leuk Res.
  
  Volume: 61 Pages: 68-76
- DOI
  10.1016/j.leukres.2017.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09645
[Journal Article] Lack of association between deletion polymorphism of BIM gene and in vitro drug sensitivity in B-cell precursor acute lymphoblastic leukemia2017
- Author(s)
  Huang Meixian、Miyake Kunio、Kagami Keiko、Abe Masako、Shinohara Tamao、Watanabe Atsushi、Somazu Shinpei、Oshiro Hiroko、Goi Kumiko、Goto Hiroaki、Minegishi Masayoshi、Iwamoto Shotaro、Kiyokawa Nobutaka、Sugita Kanji、Inukai Takeshi
- Journal Title
  
  Leukemia Research
  
  Volume: 60 Pages: 24-30
- DOI
  10.1016/j.leukres.2017.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09592, KAKENHI-PROJECT-15K09645
[Journal Article] Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression.2017
- Author(s)
  Kasai S, Furuichi Y, Ando N, Kagami K, Abe M, Nakane T, Goi K, Inukai T, Saitoh S, Ohno S, Okazaki S, Nagano O, Saya H, Sugita K.
- Journal Title
  
  Cell Death and Disease
  
  Volume: 8 Issue: 6 Pages: e2857-e2857
- DOI
  10.1038/cddis.2017.249
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-15K09645
[Journal Article] Anti-leukemic activity of bortezomib and carfilzomib on B-cell precursor ALL with IKZF1 deletion.2017
- Author(s)
  Takahashi K, Inukai T, Imamura T, Yano M, , Nemoto A, Sato H, Huang M, Abe M, Kagami K, Shinohara T, Watanabe A, Somazu S, Oshiro H, Akahane K, Goi K, Kikuchi J, Furukawa Y, Goto H, Minegishi M, Iwamoto S, Sugita K.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 12 Pages: e0188680-e0188680
- DOI
  10.1371/journal.pone.0188680
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-15K09645
[Journal Article] Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia.2016
- Author(s)
  Sera Y, Yamasaki N, Oda H, Nagamachi A, Wolff L, Inukai T, Inaba T, Honda H.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 7 Pages: 890-898
- DOI
  10.1111/cas.12945
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293227, KAKENHI-PROJECT-15K09645, KAKENHI-PROJECT-16K19575
[Journal Article] Erythrophagocytosis in T-cell type acute lymphoblastic leukaemia with near-tetraploidy.2016
- Author(s)
  Watanabe A, Akahane K, Somazu S, Oshiro H, Goi K, Miyachi H, Kiyokawa N, Inukai T, Sugita K.
- Journal Title
  
  J Clin Pathol
  
  Volume: 69 Issue: 12 Pages: 1129-1132
- DOI
  10.1136/jclinpath-2016-203915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09645
[Journal Article] Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome-Positive Lymphoid Leukemia.2016
- Author(s)
  Nemoto A, Saida S, Kato I, Kikuchi J, Furukawa Y, Maeda Y, Akahane K, Honna-Oshiro H, Goi K, Kagami K, Kimura S, Sato Y, Okabe S, Niwa A, Watanabe K, Nakahata T, Heike T, Sugita K, Inukai T.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 15 Issue: 1 Pages: 94-105
- DOI
  10.1158/1535-7163.mct-14-1065
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09645, KAKENHI-PROJECT-26670498, KAKENHI-PROJECT-26461430
[Journal Article] HMGA2 as a potential molecular target in KMT2A-AFF1-positive infant acute lymphoblastic leukaemia.2015
- Author(s)
  Wu Z, Eguchi-Ishimae M, Yagi C, Iwabuki H, Gao W, Tauchi H, Inukai T, Sugita K, Ishii E, Eguchi M.
- Journal Title
  
  Br J Haematol.
  
  Volume: 171 Issue: 5 Pages: 818-829
- DOI
  10.1111/bjh.13763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09645, KAKENHI-PROJECT-26461587, KAKENHI-PROJECT-25461597, KAKENHI-PROJECT-26670503
[Journal Article] Favorable outcome in non-infant children with MLL-AF4-positive acute lymphoblastic leukemia: a report from the Tokyo Children's Cancer Study Group.2015
- Author(s)
  Tomizawa D, Kato M, Takahashi H, Fujimura J, Inukai T, Fukushima T, Kiyokawa N, Koh K, Manabe A, Ohara A.
- Journal Title
  
  Int J Hematol.
  
  Volume: 102 Issue: 5 Pages: 602-610
- DOI
  10.1007/s12185-015-1869-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09645
[Journal Article] Anti-leukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.2014
- Author(s)
  Saito S, Nakazawa Y, Sueki A, Matsuda K, Tanaka M, Yanagisawa R, Maeda Y, Sato Y, Okabe S, Inukai T, Sugita K, Wilson MH, Rooney CM, Koike K.
- Journal Title
  
  Cytotherapy
  
  Volume: 16 Issue: 9 Pages: 1257-1269
- DOI
  10.1016/j.jcyt.2014.05.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591544, KAKENHI-PROJECT-26461574
[Journal Article] BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand (TRAIL) in Philadelphia chromosome-positive leukemia.2013
- Author(s)
  Kuroda I
- Journal Title
  
  Oncogene
  
  Volume: 32 Issue: 13 Pages: 1670-1681
- DOI
  10.1038/onc.2012.186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240089, KAKENHI-PROJECT-24591544
[Journal Article] Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors.2012
- Author(s)
  Zhang X
- Journal Title
  
  Leukemia
  
  Volume: 26 Issue: 12 Pages: 2483-2493
- DOI
  10.1038/leu.2012.139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240089, KAKENHI-PROJECT-23390253, KAKENHI-PROJECT-24591544, KAKENHI-PLANNED-22118005
[Journal Article] Endoplasmic reticulum stress inducers, but not imatinib, sensitize Philadelphia chromosome-positive leukemia cells to TRAIL-mediated apoptosis2011
- Author(s)
  Zhang X, Inukai T, Akahane K, Hirose K, Kuroda I, et al
- Journal Title
  
  Leuk Res
  
  Volume: 35 Pages: 940-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] Endoplasmic reticulum stress inducers, but not imatinib, sensitize Philadelphia chromosome-positive leukemia cells to TRAIL-mediated apoptosis2011
- Author(s)
  Zhang X, Inukai T, et al
- Journal Title
  
  Leuk Ees.
  
  Volume: 35 Issue: 7 Pages: 940-949
- DOI
  10.1016/j.leukres.2011.03.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] Regulation of cancer stem cell properties by CD9 in human B-acute lymphoblastic leukemia2011
- Author(s)
  Yamazaki H, Inukai T, et al
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 409 Issue: 1 Pages: 14-21
- DOI
  10.1016/j.bbrc.2011.04.098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22650223
[Journal Article] Successful tandem (autologous-cord blood) SCT in advanced neuroblastomas with highly amplified MYCN2011
- Author(s)
  Goi K, Inukai T, et al
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: 46 Issue: 4 Pages: 835-839
- DOI
  10.1111/j.1365-2141.2011.08965.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] A specific linkage between the incidence of TP53 mutations and type of chromosomal translocations in B-precursor acute lymphoblastic leukemia cell lines.2010
- Author(s)
  Inukai T
- Journal Title
  
  Am J Hematol.
  
  Volume: 85 Pages: 535-537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] Resistance of T-cell acute lymphoblastic leukemia totumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis2010
- Author(s)
  Akahane K, Inukai T, Hirose K, Kuroda I, et al
- Journal Title
  
  Exp Hematol
  
  Volume: 38 Pages: 885-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] 小児難治性白血病の細胞傷害因子TRAILに対する感受性の意義2009
- Author(s)
  犬飼岳史
- Journal Title
  
  日本小児血液学会雑誌 23
  
  Pages: 332-344
- NAID
  10029311164
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] Little impact of donor/recipient major mismatch for neutrophil-specific antigen NA2 on neutrophil recovery after allogeneic SCT2009
- Author(s)
  Inukai T, Goi K, Tezuka T, Uno K, Nemoto A, Takahashi K, Sato H, Akahane K, Hirose K, Honna H, Kuroda I, Kagami K, Nakamoto K, Taniguchi K, Nakazawa S, Sugita K.
- Journal Title
  
  Bone Marrow Transplant 43
  
  Pages: 229-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591246
[Journal Article] Little impact of donor/recipient major mismatch for neutrophil-specific antigen NA2 on neu2009
- Author(s)
  Inukai T, Goi K, Tezuka T, Uno K N
- Journal Title
  
  Bone Marrow Transplant. 43
  
  Pages: 229-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591246
[Journal Article] 小児難治性白血病の細胞傷害因子TRAILに対する感受性の意義(総説)2009
- Author(s)
  犬飼岳史
- Journal Title
  
  日本小児血液学会雑
  
  Volume: 23 Pages: 332-344
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] Fms-1ike kinase 3 1igand stimulation induces MLL-rearranged leukemia cells into quiescence resistant to antileukemic agents.2007
- Author(s)
  Furuichi Y. Goi K, Inukai T, Sato H, Nemoto A, Takahashi K, Akahane K, Hirose K, Honna H, Kuroda I, Zhang X, Kagami K, Hayashi Y, Harigaya K, Nakazawa S, Sugita K
- Journal Title
  
  Cancer Res 67
  
  Pages: 9851-9861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591187
[Journal Article] Fms-like Tyrosine Kinase 3 Ligand Stimulation Induces MLL-Rearranged Leukemia Cells into Quiescence Resistant to Antileukemic Agents.2007
- Author(s)
  Furuichi Y, Inukai T, Akahane K, Honna H, Kuroda I, Sugita K, ら
- Journal Title
  
  Cancer Res. 67
  
  Pages: 9852-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591246
[Journal Article] Revision of the cytological diagnosis of CNS relapse into aseptic meningitis in a patient with TEL-AML1-positive acute lymphoblastic leukaemia by FISH analysis of mononuclear cells in cerebrospinal fluid2007
- Author(s)
  Inukai T, Akahane K, Nemoto A, Kuroda I, Noguchi S, Hirose K, Honna H, Goi K, Kondo T, Iwasa S, Murata S, Kato R, Nakazawa S, Sugita K.
- Journal Title
  
  Histopathology 50(7)
  
  Pages: 947-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591246
[Journal Article] Hypercalcemia in childhood acute lymphobastic leukemia : inplication of PTHrP and frequent presence of the E2A-HLF from translocation 17;19.2007
- Author(s)
  Inukai T, Sugita K, et al.
- Journal Title
  
  Leukemia 21
  
  Pages: 288-296
- Data Source
  KAKENHI-PROJECT-18591187
[Journal Article] Monitoring neutrophil engraftment in allogeneic stem cell transplantation by flow cytometric analysis of neutrophil-specific antigens NA1 and NA22007
- Author(s)
  Inukai T, Uno K, Taniguchi K, Goi K, Tezuka T, Nemoto A, Takahashi K, Sato H, Akahane K, Hirose K, Honna H, Kagami K, Hiraoka A, Tanihiro M, Nakazawa S, Sugita K.
- Journal Title
  
  Br J Haematol 139
  
  Pages: 280-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591246
[Journal Article] Revision of the cytological diagnosis of CNS relapse into aseptic meningitis in a patient with TEL-AMLI-positive acute lymphoblastic leukaemia by FISH analysis of mononuclear cells in cerebrospinal fluid2007
- Author(s)
  Inukai T, Akahane K, Kuroda I, Honna H, Sugita K, ら
- Journal Title
  
  Histopathology 50
  
  Pages: 947-949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] Monitoring neutrophil engraftment in allogeneic stem cell transplantation by flow cytometric analysis of neutrophil-specific antigens NA1 and NA22007
- Author(s)
  Inukai T, Akahane K, Honna H, Sugita K, ら
- Journal Title
  
  Br J Haematol 139
  
  Pages: 280-283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] Revision of the cytological diagnosis of CNS relapse into aseptic meningitis in a patient with TEL-AML1-positive acute lymphoblastic leukaemia by FISH analysis of mononuclear cells in cerebrospinal fluid.2007
- Author(s)
  Inukai T, Akahane K, Kuroda I, Honna H, Sugita K, ら
- Journal Title
  
  Histopathology 50
  
  Pages: 947-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591246
[Journal Article] Hypercalcemia in childhood acute lymphoblastic leukemia : frequent implication of PTHrP and E2A-HLF from translocation 17;19.2007
- Author(s)
  T Inukai, K Hirose, K Goi, S Nakazawa, K Sugita, et al.
- Journal Title
  
  Leukemia 21
  
  Pages: 288-296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Monitoring neutrophil engraftment in allogeneic stem cell transplantation by flow cytometric analysis of neutrophil-specific antigens NA1 and NA2.2007
- Author(s)
  Inukai T, Akahane K, Honna H, Sugita K, ら
- Journal Title
  
  Br J Haematol 139
  
  Pages: 280-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591246
[Journal Article] Fms-like tyrosine kinase 3 ligand stimulation induces MLL-rearranged leukemia cells into quiescence resistant to antileukemic agents2007
- Author(s)
  Furuichi Y, Goi K, Inukai T, Sato H, Nemoto A, Takahashi K, Akahane K, Hirose K, Honna H, Kuroda I, Zhang X, Kagami K, Hayashi Y, Harigaya K, Nakazawa S, Sugita K.
- Journal Title
  
  Cancer Res 67(29)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591246
[Journal Article] Hypercalcemia in childhood acute lymphoblastic leukemia : frequent implication of PTHrP and E2A-HLF from translocation 17;19.2007
- Author(s)
  T Inukai, K Hirose, K Goi, Nakazawa, K Sugita, et al.
- Journal Title
  
  Leukemia 21
  
  Pages: 288-296
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Fms-like kinase 3 ligand stimulation induces MLL-rearranged leukemia cells into quiescence resistant to antileukemic agents.2007
- Author(s)
  Furuichi Y. Goi K, Inukai T, Sato H, Nemoto A, Takahashi K, Akahane K, Hirose K, Honna H, Kuroda I, Zhang X, Kagami K, Hayashi Y, Harigaya K, Nakazawa S, Sugita K
- Journal Title
  
  Cancer Research 67
  
  Pages: 9851-9861
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591187
[Journal Article] Fms-like kinase 3 ligand stimulation induces MLL-rearranged leukemia cells into quiescence resistant to antileukemic agents2007
- Author(s)
  Furuichi, Y., Goi, K., Inukai, T., Sato, H., Nemoto, A., Takahashi, K., Akahane, K., Hirose, K., Hanna, H., Kuroda, I., Zhang, X., Kagami, K., Hayashi, Y., Harigaya, K., Nakazawa, S., Sugita, K
- Journal Title
  
  Cancer Research 67
  
  Pages: 9851-9861
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591187
[Journal Article] Hypercalcemia in childhood acute lymphoblastic leukemia : frequent implication of PTHrP and E2A-HLF from translocation 17; 19.2007
- Author(s)
  T Inukai, K Hirose, K Goi, S Nakazawa, K Sugita, et al.
- Journal Title
  
  Leukemia 21
  
  Pages: 288-296
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] Fms-like Tyrosine Kinase 3 Ligand Stimulation Induces MLL-Rearranged Leukemia Cells into Quiescence Resistant to Antileukemic Agents2007
- Author(s)
  Furuichi Y, Inukai T, Akahane K, Honna H, Kuroda I, Sugita K, ら
- Journal Title
  
  Cancer Res. 67
  
  Pages: 9852-9861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.2006
- Author(s)
  Goi K, Sugita K, Inukai T, et al.
- Journal Title
  
  Bone marrow Transplantation 37
  
  Pages: 115-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.2006
- Author(s)
  Goi K, Sugita K, Tezuka T, Sato H, Uno K, Inukai T, Hamada Y, Nakazawa S.
- Journal Title
  
  Bone Marrow Transpl 37
  
  Pages: 115-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.2006
- Author(s)
  Goi K, Sugita K, Tezuka T, Sato H, Uno K, Inukai T, Nakazawa S.
- Journal Title
  
  Bone Marrow Transplant 37(1)
  
  Pages: 115-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Okamoto T, Nemoto A, Akahane K, Takahashi K, Sato H, Goi K, Nakazawa S, Sugita K.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-365
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Okamoto T, Nemoto A, Akahane K, Takahashi K, Sato H, Goi K, Nakazawa S, Sugita K.
- Journal Title
  
  Leukemia 20(2)
  
  Pages: 363-365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Natural pregnancy and delivery after bone marrow transplantation in a Fanconi anemia patient.2006
- Author(s)
  Goi K, Sugita K, Inukai T, et al.
- Journal Title
  
  Brit H Haematol 135
  
  Pages: 410-411
- Data Source
  KAKENHI-PROJECT-18591187
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Goi K, Sugita K, et al.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Resistance of infant leukemia with MLL rearrangement to tumornecrosis factor-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antitumor immunity.2006
- Author(s)
  Inukai T, Goi K, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Data Source
  KAKENHI-PROJECT-18591187
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL/AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Okamoto T, Nemoto A, Akahane K, Takahashi K, Sato H, Goi K, Nakazawa S, Sugita K.
- Journal Title
  
  Leukemia 20
  
  Pages: 363-365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.2006
- Author(s)
  Goi K, Sugita K, Tezuka T, Sato H, Uno K, Inukai T, Nakazawa S.
- Journal Title
  
  Bone Marrow Transplant 37・1
  
  Pages: 115-116
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Akahane K, Goi K, Nakazawa S, Sugita K. et al.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antitumor immunity.2006
- Author(s)
  Inukai T, Hirose K, Goi K, Honna H, T, Nakazawa S, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Okamoto T, Nemoto A, Akahane K, Takahashi K, Sato H, Goi K, Nakazawa S, Sugita K.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-365
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Goi K, Nakazawa S, Sugita K et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 363-365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antiumor immunity.2006
- Author(s)
  Inukai T, Hirose K, Goi K, Honna H, T, Nakazawa S, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.2006
- Author(s)
  Goi K, Sugita K, Tezuka T, Sato H, Uno K, Inukai T, Nakazawa S.
- Journal Title
  
  Bone Marrow Transplant 37・1
  
  Pages: 115-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antitumor immunity.2006
- Author(s)
  Inukai T, Hirose K, Goi K, Honna H, T, Nakazawa S, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL/AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Goi K, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 363-365
- Data Source
  KAKENHI-PROJECT-18591187
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Goi K, Nakazawa S, Sugita K et al.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-365
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Natural pregnancy and delivery after allogeneic bone marrow transplantation in a Fanconi anaemia patient.2006
- Author(s)
  Goi K, Sugita K, Nakamura M, Inukai T, Honna H, Hirose K, Kuroda I, Hoshi K, Nakazawa S.
- Journal Title
  
  British Journal of Haematology 135
  
  Pages: 410-411
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-induc ng ligand : a possible mechanism for poor sensitivity to antitumor immunity.2006
- Author(s)
  Inukai T, Hirose K, Goi K, Honna H, T, Nakazawa S, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Natural pregnancy and delivery after allogeneic bone marrow transplantation in a Fanconi anaemia patient.2006
- Author(s)
  Goi K, Sugita K, Inukai T, Honna H, Hirose K, Nakazawa S, et al.
- Journal Title
  
  British Journal of Haematology 135
  
  Pages: 410-411
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Natural pregnancy and delivery after allogeneic bone marrow transplantation in a Fanconi anaemia patient.2006
- Author(s)
  Goi K, Sugita K, Nakamura M, Inukai T, Honna H, Hirose K, Kuroda I, Hoshi K, Nakazawa S
- Journal Title
  
  British Journal of Haematology 135
  
  Pages: 410-411
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common β chain of cytokine receptors.2005
- Author(s)
  T.Inukai, T.Inaba, J.Dang, R.A.T.Look, Y.Arinobu, H.Iwasaki, K.Akashi, K.Kagami, K.Goi, K.Sugita, S.Nakazawa et al.
- Journal Title
  
  Blood 105・11
  
  Pages: 4437-4444
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] TEF, an anti-apcptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common b chain of cytokine receptors.2005
- Author(s)
  T.Inukai, Y.Arinobu, H.Iwasaki, K.Akashi, K.Kagami, K.Goi, K.Sugita, S.Nakazawa.et al.
- Journal Title
  
  Blood 105・11
  
  Pages: 4437-4444
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K, Goi K, Sugita K, Nakazawa S. et al.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy2005
- Author(s)
  Xiaochum Z, Inukai T, Hirose K, Akahane K, Nemoto A, Takahashi K, Sato H, Goi K, Kagami K, Sugita K, Nakazawa S.
- Journal Title
  
  Int J Hematol 82
  
  Pages: 132-136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common β chain of cytokine receptors.2005
- Author(s)
  T.Inukai, T.Inaba, J.Dang, R.Kuribara, K.Ozawa, A.Miyajima, W.Wu, A.T.Look, Y.Arinobu, H.Iwasaki, K.Akashi, K.Kagami, K.Goi, K.Sugita, S.Nakazawa
- Journal Title
  
  Blood 105(11)
  
  Pages: 4437-4444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common β chain of cytokine receptors.2005
- Author(s)
  T.Inukai, T.Inaba, J.K.Goi, K.Sugita, S.Nakazawa et al.
- Journal Title
  
  Blood 105・11
  
  Pages: 4437-44
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K, Nemoto A, Takahashi K, Sato H, Kagami K, Goi K, Sugita K, Nakazawa S.
- Journal Title
  
  International Journal of Hematol. 82(2)
  
  Pages: 132-136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] TEF, anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulationg expression of the common β chain of cytokine receptors.2005
- Author(s)
  Inukai T, Goi K, Sugita K, el.al
- Journal Title
  
  Blood 105・11
  
  Pages: 4437-44
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common b chain of cytokine receptors.2005
- Author(s)
  Inukai T, Sugita K, et al.
- Journal Title
  
  Blood 105
  
  Pages: 4437-4444
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Induction of impaired membrane phospholipids asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Goi K, Sugita K, et al.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] TFF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down regulating expression of the common {beta} chain of cytokine receptors.2005
- Author(s)
  Inukai T, Inaba T, K, Goi K, Sugita K, Nakazawa S. et al.
- Journal Title
  
  BLOOD (in press)
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Kagami K, Goi K, Sugita K, Nakazawa S e al.
- Journal Title
  
  International Journal of Hematology 82
  
  Pages: 132-136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common b chain of cytokine receptors.2005
- Author(s)
  T.Inukai, Y.Arinobu, H.Iwasaki, K.Akashi, K.Kagami, K.Goi, K.Sugita, S.Nakazawa et al.
- Journal Title
  
  Blood 105
  
  Pages: 4437-4444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Kagami K, Goi K, Sugita K, Nakazawa S et al.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocyte after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K.Nemoto A, Takahashi K, Sato H, Kagami K, Goi K, Sugita K, Nakazawa S.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-136
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common b chain of cytokine receptors.2005
- Author(s)
  Inukai T, Inaba T, Dang J, Kuribara R, Ozawa K, Miyajima A, Wu Wenshu, Look AT, Arinobu Y, Iwasaki H, Akashi K, Kagami K, Goi K, Sugita K, Nakazawa S.
- Journal Title
  
  Blood 105
  
  Pages: 4437-4444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down regulating expression of the common {beta} chain of cytokine receptors.2005
- Author(s)
  Inukai T, Inaba T, K, Goi K, Sugito K, Nakazawa S.et al.
- Journal Title
  
  BLOOD (in press)
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K, Nemoto A, Takahashi K, Sato H, Kagami K, Goi K, Sugita K, Nakazawa S.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-136
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common β chain of cytokine receptors.2005
- Author(s)
  T.Inukai, T.Inaba, J.Dang, R.A.T.Look, Y.Arinobu, H.Iwasaki, K.Akashi, K.Kagami, K.Goi, K.Sugita, S.Nakazawa et al.
- Journal Title
  
  Blood 105・11
  
  Pages: 4437-4444
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Hepatocyte growth factor prevents small airway epithelial cells from apoptosis induced by tumor necrosis factor-□ or oxidative stress.2004
- Author(s)
  Okada M, Sugita K, Inukai T, Goi K, et al.
- Journal Title
  
  Pediatr Res. 56・
  
  Pages: 336-344
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Nuclear accumulation of β-catenin without an additional somatic mutation in cording region of the APC gene in hepatoblastoma from a familial adenomatous polyposis patient.2004
- Author(s)
  Inukai T, Sugita K, et al.
- Journal Title
  
  Oncol Rep. 11・
  
  Pages: 121-126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein.2004
- Author(s)
  Matsunaga T, Inaba T, Inukai T, Look AT, Kurosawa H, et al.
- Journal Title
  
  BLOOD 103・8
  
  Pages: 3185-3191
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Roles of Bim in apoptosis of normal and Bcr-Abl-expressiong hematopoietic progenitors.2004
- Author(s)
  Kuribara R, Inukai T, Sugita K, et al.
- Journal Title
  
  Molecular and Cellular Biology 24・12
  
  Pages: 6172-83
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Pivotal roles of Bim, a proapoptotic relative of Bcl-2, in the leukemogenesis of chronic myeloid leukemia.2004
- Author(s)
  Kuribara R, Honda H, Matsui H, Shinjyo T, Inukai T, Sugita K, Nakazawa S, Hirai H, Ozawa K, Inaba T.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6172-6183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Non-T-cell-depleted HLA haploidentical stem cell transplantation based on feto-maternal microchimerizm in pediatric patients with advanced malignancies.2004
- Author(s)
  Yoshihara T, Morimoto A, Inukai T, Kuroda H, Ishida H, Sugita K, Goi K, Imamura T, Todo S, Maruya E, Saji H, Nakazawa S, Imashuku S.
- Journal Title
  
  Bone Marrow Transpl 34
  
  Pages: 373-375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Hepatocyte growth factor prevents small airway epithelial cells from apoptosis induced by tumor necrosis factor-α or oxidative stress.2004
- Author(s)
  Okada M, Sugita K, Inukai T, Goi K, Kagami K, Kawasaki K, Nakazawa S.
- Journal Title
  
  Pediatr Res. 56
  
  Pages: 336-344
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein.2004
- Author(s)
  T.Matsunaga, T.Inaba, H.Matsui, M.Okuya, A.Miyajima, T.Inukai, T.Funabiki, M.Endo, AT.Look, H.Kurosawa
- Journal Title
  
  Blood 103
  
  Pages: 3185-3191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Roles of Bim in apoptosis of normal and Bcr-Ab1-expressing hematopoietic progenitors.2004
- Author(s)
  R.Kuribara, H.Honda, H.Matsui, T.Shinjyo, T.Inukai, K.Sugita, S.Nakazawa, H.Hirai, K.Ozawa, T.Inaba
- Journal Title
  
  Molecular and Cellular Biology 24
  
  Pages: 6172-6183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors.2004
- Author(s)
  Kuribara R, Inukai T, Sugita K, Nakazawa S, Inaba T. et al.
- Journal Title
  
  Mol Cell Biol 24・12
  
  Pages: 6172-6183
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors.2004
- Author(s)
  Kuribara R, Inukai T, Sugita K, Nakazawa S, Inaba T.et al.
- Journal Title
  
  Mol Cell Biol 24・12
  
  Pages: 6172-6183
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Non-T-cell-depleted HLA haploidentical stem cell transplantation based on feto-maternal microchimerism in pediatric patients with advanced malignancies.2004
- Author(s)
  Yoshihara T, Morimoto A, Inukai T, Kuroda H, Ishida H, Sugita K, Goi K, Imamura T, Todo S, Maruya E, Saji H, Nakazawa S, Imashuku S.
- Journal Title
  
  Bone Marrow Transplant. 34(4)
  
  Pages: 373-375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Non-T-cell-depleted HLA haploidentical stem cell transplantation based on feto-maternal microchimerism in pediatric patients with advanced malignancies.2004
- Author(s)
  Yoshihara T, Inukai T, Sugita K, Goi K, et al.
- Journal Title
  
  Bone Marrow Transplant. 34・4
  
  Pages: 373-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Non-T cell-depleted HLA haploidentical stem cell transplantation based on feto-maternal microchimerizm in pediatric patients with advanced malignancies.2004
- Author(s)
  Yoshihara T, Inukai T, Goi K, Sugita K, et al.
- Journal Title
  
  Bone marrow Transplantation 34・
  
  Pages: 373-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Feasibility of HLA-haploidentical hematopoietic stem-cell transplantation between non-inherited maternal antigen (NIMA)-mismatched family members linked with long-term feto-maternal microchimerism.2004
- Author(s)
  Ichinohe T, Uchiyama T, Shimazaki C, Matsuo K, Tamaki S, Hino M, Watanabe A, Hamaguchi M, Adachi S, Gondo H, Uoshima N, Yoshihara T, Hatanaka K, Fujii H, Kawa K, Kawanishi K, Oka K, Kimura H, Itoh M, Inukai T, Maruya E, Saji H, Kodera Y
- Journal Title
  
  Blood 104
  
  Pages: 3821-3828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors.2004
- Author(s)
  Kuribara R, Inukai T, Sugita K, Nakazawa S, Inaba T. et al.
- Journal Title
  
  Molecula Cellular Biology 24・12
  
  Pages: 6172-83
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Feasibility of HLA-haploidentical hematopoietic stem-cell transplantation between non-inherited maternal antigen (NIMA)-mismatched family members linked with long-term feto-maternal microchimerism.2004
- Author(s)
  Ichinohe T, Inukai T, et al.
- Journal Title
  
  Blood 104・
  
  Pages: 3821-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] E2A転写因子の異常とALL2004
- Author(s)
  犬飼岳史, 合井久美子, 黒澤秀光, 稲葉俊哉
- Journal Title
  
  血液・腫瘍科 49
  
  Pages: 65-73
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591096
[Journal Article] Nuclear accumulation of β-catenin without an additional somatic mutation in cording region of the APC gene in hepatoblastoma from a familial adenomatous polyposis patient.2004
- Author(s)
  Inukai T, Furuuchi K, Sugita K, Uno K, Mishina M, Ooi A, Sasaki F, Hamada J, Moriuchi T, Nakazawa S.
- Journal Title
  
  Oncol Rep. 11
  
  Pages: 121-126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591018
[Journal Article] Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein.2004
- Author(s)
  Matsunaga T, Inaba T, Inukai T, Look AT, Kurosawa H, et al.
- Journal Title
  
  Blood 103・8
  
  Pages: 3185-91
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Hepatocyte growth factor protects small airway epithelial calls from apoptosis induced by tumor necrosis factor-alpha or oxidative stress.2004
- Author(s)
  Okada M, Sugita K, Inukai T, Goi K, Kagami K, Kawasaki K, Nakazawa S.
- Journal Title
  
  Pediatr Res 56・3
  
  Pages: 336-344
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells.2003
- Author(s)
  Uno K, Inukai T, Kayagaki N, Goi K, et al.
- Journal Title
  
  blood 101
  
  Pages: 3658-3667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591096
[Journal Article] TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells.2003
- Author(s)
  Uno K, Inukai T, Kayagaki N, Goi K, et al.
- Journal Title
  
  Blood 101
  
  Pages: 3658-3667
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591096
[Journal Article] Oncogenic fusion E2A-HLF sensitize t(17 ; 19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K, Kuroda I, et al
- Journal Title
  
  Leukemia
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand(TRAIL) in Philadelphia chromosome-positive leukemia
- Author(s)
  Kuroda I, Inukai T, Akahane K, Hirose K, et al
- Journal Title
  
  Oncogene
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Patent] 胃がん細胞の増殖抑制剤、胃がんの腫瘍形成抑制剤、　　　　　　胃がんを治療するための医薬、及び薬効予測方法2021
- Inventor(s)
  犬飼岳史, 渡辺敦, 三宅邦夫, 赤羽弘資
- Industrial Property Rights Holder
  国立大学法人山梨大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-116120
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19H03615
[Patent] 神経膠腫の予後判定方法2019
- Inventor(s)
  三宅邦夫,犬飼岳史,渡邊敦,木内博之,川瀧智之,埴原光人,他
- Industrial Property Rights Holder
  国立大学法人山梨大学, 積水メディカル株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] TKI-resistance in a human Ph+ leukemia model with T315I-containing compound mutations of BCR::ABL12023
- Author(s)
  Nguyen Thao TT, Tamai Minori, Harama Daisuke, Kagami Keiko, Komatsu Chiaki, Kasai Shin, Akahane Koushi, Goi Kumiko, Inukai Takeshi
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] BCP-ALL細胞株のinotuzumab ozogamicin感受性におけるCD22陽性率の意義2023
- Author(s)
  笠井慎, 赤羽弘資, 玉井望雅, 加賀美恵子, 小松千亜紀, 清河信敬, Nguyen TT, 後藤裕明, 峯岸正好, 稲葉俊哉, 岩本彰太郎, 合井久美子, 犬飼岳史
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] Ph陽性ALLにおけるインテグリンα6の発現誘導を介するラミニン接着へのBCR::ABL1の関与2023
- Author(s)
  高橋和也, Nguyen TT, 玉井望雅, 原間大輔, 笠井慎, 赤羽弘資, 合井久美子, 加賀美恵子, 小松千亜紀, 犬飼岳史
- Organizer
  第65回日本小児血液がん学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] Establishment of a human acute lymphoblastic leukemia model with relapse-specific mutation of the TP53 gene using the prime editing system2022
- Author(s)
  Nguyen Thao, Tamai Minori, Inaba Toshiya, Nagamachi Akiko, Kagami Keiko, Harama Daisuke, Kasai Shin, Akahane Koshi, Goi Kumiko, Inukai Takeshi
- Organizer
  第64回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] p210 and p190 BCR::ABL1 induce different gene expression profiles in the artificial Philadelphia chromosome-positive leukemias created by CRISPR/Cas9 system2022
- Author(s)
  Tamai Minori, Nguyen Thao, Komatsu Chiaki, Kagami Keiko, Kasai Shin, Harama Daisuke, Akahane Koshi, Goi Kumiko, Inukai Takeshi
- Organizer
  第64回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] TCF3::HLF陽性白血病の難治性病態とその克服　17;19転座型ALLにおける化学療法に対する耐性と免疫学的な抗白血病効果に対する高感受性の機序2022
- Author(s)
  犬飼岳史
- Organizer
  第64回日本小児血液がん学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] TKIs suppress the laminin adhesion of Ph+ALL2021
- Author(s)
  高橋和也, 佐藤広樹, 齋藤衣子, 渡邊敦, 杣津晋平, 赤羽弘資, 合井久美子, 中村誠, 古市嘉行, 根本篤, 加賀美恵子, グエンタオ, 杉田完爾, 犬飼岳史
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Establishment of thiopurine-resistant acute lymphoblastic human lymphoid leukemia models acquiring relapse-specific mutations in the PRPS1 gene using CRISPR/Cas9 system2021
- Author(s)
  Nguyen Thao, Tamai Minori, Harama Daisuke, Kagami Keiko, Kasai Shin, Watanabe Atsushi, Akahane Koshi, Goi Kumiko, Inukai Takeshi
- Organizer
  第63回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Introduction of relapsed ALL-specific mutation in NT5C2 into lymphoid leukemia model by CRISPR/Cas92021
- Author(s)
  Nguyen Thao, Tamai Minori, Harama Daisuke, Kagami Keiko, Kasai Shin, Watanabe Atsushi, Akahane Koshi, Goi Kumiko, Inukai Takeshi
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Associations of NR3C1 mutations and glucocorticoid resistance in BCP-ALL cell lines2021
- Author(s)
  玉井望雅, 笠井慎, タオグエン, 加賀美恵子, 渡邊敦, 赤羽弘資, 矢ヶ崎英晃, 合井久美子, 三宅邦夫, 後藤裕明, 峯岸正好, 岩本彰太郎, 犬飼岳史
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Molecular mechanisms for drug-resistance of poor-prognostic and relapsed acute lymphoblastic leukemia2020
- Author(s)
  Takeshi Inukai
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Distinctive drug response profiling of MEF2D-fusion-positive ALL cell lines.2019
- Author(s)
  Inukai T, et al.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Involvement of BCR-ABL1 in higher cell surface expression level of CD49f (integrin α6) in Ph+ALL cells.2019
- Author(s)
  Takahashi K, Inukai T, et al.
- Organizer
  第61回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Significance of methylation status of DR4/DR5 genes in susceptibility of BCP-ALL cell lines to cytotoxic ligand TRAIL.2019
- Author(s)
  Watanabe A, Inukai T, et al.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Induction of ponatinib-resistant T315M gatekeeper mutation into Ph+ leukemia cell lines by homologous recombination using CRISPR/Cas9 system.2019
- Author(s)
  Harama D, Inukai T, et al.
- Organizer
  第61回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Association of NUDT15 gene polymorphism with cellular metabolism of thiopurine in BCP-ALL cell line.2019
- Author(s)
  Somazu S, Inukai T, et al.
- Organizer
  第61回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Prevalence of MEF2D fusions in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cell lines.2019
- Author(s)
  Akahane K, Inukai T, et al.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Methylation status of asparaginase synthetase (ASNS) gene in childhood T-cell acute lymphoblastic leukemia (T-ALL).2019
- Author(s)
  Akahane K, Inukai T, et al.
- Organizer
  第61回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] 細胞質内μ鎖陽性のB前駆細胞性ALLに対するIdelalisibの抗白血病活性2017
- Author(s)
  高橋和也, 犬飼岳史, 佐藤広樹, 廣瀬衣子, 渡邊敦, 杣津晋平, 合井久美子, 加賀美恵子, 阿部正子, 照井君典, 後藤裕明, 峰岸正好, 岩本彰太郎, 杉田完爾
- Organizer
  第79回日本血液学会
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] Association between asparaginase synthetase gene methylation status with karyotypes in childhood BCP-ALL2017
- Author(s)
  Watanabe A, Inukai T
- Organizer
  第59回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] BCP-ALL細胞株のthiopurine感受性におけるNT5C2遺伝子変異の意義2017
- Author(s)
  杣津晋平, 犬飼岳史, 黄媚賢, 阿部正子, 加賀美恵子, 渡邊敦, 大城浩子, 赤羽弘資, 合井久美子, 杉田完爾
- Organizer
  第79回日本血液学会
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] B 前駆細胞型 ALL 細胞株の Ara-C 感受性における DCK遺伝子多型と変異の意義2017
- Author(s)
  篠原珠緒, 犬飼岳史, 渡邊敦, 大城浩子, 赤羽弘資, 合井久美子, 黄媚賢, 阿部正子, 加賀美恵子, 後藤裕明, 峰岸正好, 岩本彰太郎, 杉田完爾
- Organizer
  第59回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] B前駆細胞性ALLのAraC感受性におけるdeoxycytidine kinaseの意義2016
- Author(s)
  黄媚賢, 犬飼岳史, 阿部正子, 加賀美恵子, 後藤裕明, 峯岸正好, 岩本彰太郎, 杉原英志, 渡邊敦, 大城浩子, 赤羽弘資, 合井久美子, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] B前駆細胞型ALL細胞株の薬剤感受性におけるCASP8遺伝子のins/del多型の意義2016
- Author(s)
  篠原珠緒, 犬飼岳史, 渡邊敦, 大城浩子, 赤羽弘資, 合井久美子, 黄媚賢, 阿部正子, 加賀美恵子, 後藤裕明, 峰岸正好, 岩本彰太郎, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] B前駆細胞型ALLのMTX感受性におけるTYMS遺伝子のtandem duplication多型の意義2016
- Author(s)
  加藤大貴, 犬飼岳史, 三宅邦夫, 加賀美恵子, 阿部正子, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] BCP-ALL細胞株のABT737感受性におけるBcl2ファミリー遺伝子の意義2016
- Author(s)
  黒田格, 犬飼岳史, 黄媚賢, 加賀美恵子, 阿部正子, 中村誠, 古市嘉行, 佐藤広樹, 高橋和也, 根本篤, 廣瀬衣子, 小鹿学, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] BCP-ALL細胞株のthiopurine感受性におけるNUDT15遺伝子多型の意義2016
- Author(s)
  杣津晋平, 犬飼岳史, 森山貴也, Yang Jun, 阿部正子, 加賀美恵子, 渡邊敦, 大城浩子, 赤羽弘資, 合井久美子, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] Triggering of CD44 by ULMW hyaluronan induces necrosis of MLL-rearranged ALL.2015
- Author(s)
  笠井慎、古市嘉行、安藤徳江、犬飼岳史、合井久美子、加賀美恵子、阿部正子、杉田完爾
- Organizer
  第７７回日本血液学会
- Place of Presentation
  ホテル日航金沢（石川県、金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25461585
[Presentation] Molecular aspects of chemoresistance in poor prognostic ALL2015
- Author(s)
  Takeshi Inukai
- Organizer
  日本小児血液がん学会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] 白血病細胞株を用いた小児ALLにおける抗がん剤感受性解析システムの確立2015
- Author(s)
  犬飼岳史, 黄媚賢, 渡邊敦, 杣津晋平, 篠原珠緒, 合井久美子, 加賀美恵子, 阿部正子, 後藤裕明, 杉田完爾
- Organizer
  日本小児科学会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] Significance of 19-bp deletion polymorphism of DHFR gene in MTX-sensitivity of B-cell precursor ALL2015
- Author(s)
  加藤大貴, 犬飼岳史, 黄媚賢, 加賀美恵子, 阿部正子, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] Association of receptor isoform profiling and SNP typing of glucocorticoid(GC) with GC-sensitivity of BCP-ALL2015
- Author(s)
  黄媚賢, 犬飼岳史, 加賀美恵子, 阿部正子, 篠原珠緒, 渡辺敦, 杣津晋平, 大城浩子, 合井久美子, 後藤裕明, 峯岸正好, 岩本彰太郎, Kevin Urayama, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] Association of rs924607 polymorphism located in CEP72 gene promoter with vincristine sensitivity of BCP-ALL in Japanese population2015
- Author(s)
  小鹿学, 犬飼岳史, 黄媚賢, 加賀美恵子, 阿部正子, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] Association of germline polymorphisms in the ARID5B gene with its gene expression level and chemoresistance of BCP-ALL2015
- Author(s)
  玉井望雅, 犬飼岳史, 黄媚賢, 篠原珠緒, 渡邊敦, 杣津晋平, 大城浩子, 古市嘉行, 合井久美子, 阿部正子, 加賀美恵子, 後藤裕明, 峯岸正好, 岩本彰太郎, Kevin Urayama , 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] Association of GSTM1 and GSTT1 deletion polymorphisms with MTX-sensitivity of BCP-ALL2015
- Author(s)
  篠原珠緒, 犬飼岳史, 渡邊敦, 杣津晋平, 大城浩子, 合井久美子, 黄媚賢, 阿部正子, 加賀美恵子, 後藤裕明, 峯岸正好, 岩本彰太郎, 阿部洋, 杉田完爾
- Organizer
  日本小児血液がん学会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K09645
[Presentation] 細胞傷害因子TRAILのPh陽性白血病に対する抗白血病効果は骨髄ニッチ条件下でも維持される2013
- Author(s)
  黄媚賢, 犬飼岳史ら
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク（福岡県福岡市）
- Data Source
  KAKENHI-PROJECT-24591544
[Presentation] 骨髄低酸素環境におけるPh+白血病細胞の抗がん剤耐性とHIF-1αの関与2013
- Author(s)
  黒田格, 犬飼岳史ら
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク（福岡県福岡市）
- Data Source
  KAKENHI-PROJECT-24591544
[Presentation] 小児急性リンパ性白血病の進展におけるPI9遺伝子発現の意義2013
- Author(s)
  鈴木隆和, 犬飼岳史ら
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク（福岡県福岡市）
- Data Source
  KAKENHI-PROJECT-24591544
[Presentation] TRAIL-mediated GVL effect against childhood ALL with t(17:19)2012
- Author(s)
  Inukai Takeshi, Akahane Koshi, Honna-Oshiro Hiroko, Watanabe Atsushi, et al.
- Organizer
  日本血液学会
- Place of Presentation
  京都国際会館（京都市）
- Data Source
  KAKENHI-PROJECT-24591544
[Presentation] TRAIL-sensitivity of Ph-positive leukemia cells in low oxygen environment corresponding to bone marrow2012
- Author(s)
  Somazu Shinpei, Kuroda Itaru, Watanabe Atushi, Inukai Takeshi, et al
- Organizer
  日本小児血液・がん学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24591544
[Presentation] B前駆細胞型リンパ性白血病におけるCD9発現を指標とした白血病幹細胞のTRAIL感受性の解析2012
- Author(s)
  三上学, 犬飼岳史, 杣津晋平, 渡邊敦, ほか
- Organizer
  日本小児血液・がん学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24591544
[Presentation] BCR-ABL regulates death receptor expression for TRAIL in Ph+ leukemia2012
- Author(s)
  Kuroda Itaru, Inukai Takeshi, Kikuchi Jiro, Furukawa Yusuke, et al.
- Organizer
  日本血液学会
- Place of Presentation
  京都国際会館（京都市）
- Data Source
  KAKENHI-PROJECT-24591544
[Presentation] BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand(TRAIL) inPhiladelphia chromosome-positive leukemia2011
- Author(s)
  Kuroda I, Inukai T, Akahane K, HiroseK, et al
- Organizer
  53th American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-21591356
[Presentation] BCR-ABL Regulates Death Receptor Expression for TNF-Related Apoptosis-Inducing Ligand (TRAIL) in Philadelphia Chromosome-Positive Leukemia2011
- Author(s)
  Kuroda I, Inukai T, et al
- Organizer
  アメリカ血液学会
- Place of Presentation
  サンディェゴ国際会議場(アメリカ合衆国)
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-21591356
[Presentation] T細胞型急性リンパ性白血病のTRAIL耐性へのTRAIL受容体DR4/DR5遺伝子のメチル化とプロモーター活性の関与2009
- Author(s)
  赤羽弘資,犬飼岳史,廣瀬衣子,黒田格, ほか
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21591356
[Presentation] BCR-ABLはPh1陽性白血病細胞のTRAILに対するdeath受容体の発現に関与する2009
- Author(s)
  黒田格,犬飼岳史,張暁春,廣瀬衣子,赤羽弘資, ほか
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21591356
[Presentation] Philadelphia染色体陽性白血病細胞におけるImatinibによる小胞体ストレス誘導作用とTRAIL感受性の検討2009
- Author(s)
  張暁春,犬飼岳史,黒田格,赤羽弘資,廣瀬衣子, ほか
- Organizer
  第51回日本小児血液学会総会
- Place of Presentation
  幕張
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21591356
[Presentation] GVL効果を仲介する細胞傷害因子TRAILは低酸素条件下で化学療法耐性の白血病幹細胞に対して細胞死を誘導する
- Author(s)
  三上学, 犬飼岳史, 合井久美子, 阿部正子, 加賀美恵子, 山崎裕人, 杉田完爾
- Organizer
  日本小児血液がん学会学術集会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-24591544
[Presentation] Possible involvement of PI9 in the development of acute lymphoblastic leukemia
- Author(s)
  Suzuki R, Inukai T, Watanabe A, Somazu S, Goi Ko, Taki T, Ikawa T, Abe M, Kagami K, Sugita K
- Organizer
  日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-24591544

1. GOI Kumiko (70324192)

# of Collaborated Projects: 13 results

# of Collaborated Products: 77 results
2. SUGITA Kanji (60138055)

# of Collaborated Projects: 9 results

# of Collaborated Products: 45 results
3. AKAHANE Koshi (90377531)

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4. HONNA Hiroko (50377537)

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5. KURODA Itaru (30402051)

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6. HIROSE Kinuko (70436880)

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# of Collaborated Products: 12 results
7. NAKAZAWA Shinpei (90090034)

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# of Collaborated Products: 20 results
8. WATANABE Atsushi (30610498)

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9. SHINOHARA Tamao (80747452)

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10. 原間大輔 (10774078)

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11. 手塚徹

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12. 玉井望雅 (90747453)

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13. NEMOTO Atsushi

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15. YAMAUCHI Takahiro

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16. MIYAKE Kunio

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17. SANADA Masashi

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18. SIVASUNDARAM Karnan

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19. OHKI Kentaro

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20. SATOU Shinji

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22. 本田善一郎

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# of Collaborated Products: 1 results
40. 芦原英司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 戸田侑紀

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42. 高折晃史

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43. 進藤岳郎

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# of Collaborated Products: 1 results
44. 末延聡一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 佐藤聡美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

INUKAI Takeshi 犬飼 岳史

Inukai Takeshi 犬飼 岳史

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難治性急性リンパ性白血病に対するプレシジョン・メディシンを目指した多分野融合研究Principal Investigator

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Integrated study aiming at development of precision medicine for poor prognostic acute lymphoblastic leukemiaPrincipal Investigator

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Establishment of ALL cell line bank to identify genetic factors involving in drug-sensitivity for future precision medicinePrincipal Investigator

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Research for clinical application of cytotoxic ligands for graft-versus-leukemia effect against childhood leukemiaPrincipal Investigator

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Clinical significance of cytotoxic factor-mediated graft-versus-leukemia effect against high-risk childhood leukemiaPrincipal Investigator

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Involvement of Slug transcription factor, a human homolog of ces-1 of C. elegans, in the regulation of apoptotic cell death of leukemia cellsPrincipal Investigator

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細胞傷害因子の移植片対白血病効果における意義と臨床応用に向けた研究Principal Investigator

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Anti-leukemic activity of cytotoxic ligands against poor-prognostic childhood leukemiaPrincipal Investigator

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Anti-leukemic activities of TNF-family ligands in childhood poor-prognostic leukemiaPrincipal Investigator

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INUKAI Takeshi 犬飼岳史

Inukai Takeshi 犬飼岳史

[Book] ゲノム編集技術を応用した製品開発とその実用化　第5章8節「ゲノム編集技術を用いた薬剤耐性をもつ白血病細胞株の樹立と医薬品評価への応用」ゲノム編集技術を応用した製品開発とその実用化　第5章8節2021