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Ozawa Hiroyuki  小澤 宏之

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… Alternative Names

小澤 宏之  オザワ ヒロユキ

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Researcher Number 30327621
Other IDs
Affiliation (Current) 2025: 慶應義塾大学, 医学部(信濃町), 教授
2025: 独立行政法人国立病院機構(東京医療センター臨床研究センター), その他部局等, その他
Affiliation (based on the past Project Information) *help 2021 – 2025: 慶應義塾大学, 医学部(信濃町), 教授
2016 – 2020: 慶應義塾大学, 医学部(信濃町), 講師
2017: 慶應義塾大学, 医学部, 専任講師
2014 – 2015: 慶應義塾大学, 医学部, 講師
2006: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 聴覚平衡覚研究部, 研究員
2005: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 聴覚・平衡覚研究部, 研究員
Review Section/Research Field
Principal Investigator
Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Except Principal Investigator
Basic Section 56050:Otorhinolaryngology-related / Basic Section 57060:Surgical dentistry-related / Surgery related to the biological and sensory functions and related fields / Otorhinolaryngology
Keywords
Principal Investigator
頭頸部癌 / 低酸素応答因子 / 腫瘍免疫 / 転移 / 低酸素誘導因子 / 免疫療法 / 頭頸部傍神経節腫 / 低酸素 / PD-L1 / 免疫応答 … More / 下咽頭癌 / 中咽頭癌 / ANGPTL4 / 細胞培養 / 細胞増殖 / 免疫染色 / コネキシン … More
Except Principal Investigator
PDXモデル / CD44v / 甲状腺オルガノイド / Angiopoietin-like 4 / 口腔癌 / がん幹細胞 / 抗がん剤 / GSH / PDX / 活性酸素 / ピモジド / 頭頸部がん / 顔面神経麻痺 / 内視鏡下耳科手術 / 拡張現実 / 耳科学 / CD44v / PDXマウスモデル / 口腔がん / 口腔扁平上皮癌 / 中咽頭顔 / 下咽頭顔 / 中咽頭癌 / 下咽頭癌 / 経口切除 / COX2 / ELPS / TOVS / 頭頸部癌 / 咽頭癌 Less
  • Research Projects

    (12 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (21 People)
  •  頭頸部癌におけるAngiopoietin-like4の腫瘍促進・抑制に関するメカニズムの解明

    • Principal Investigator
      御子柴 卓弥
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Keio University
  •  甲状腺オルガノイドを用いた甲状腺機能低下症の病態解明と新規治療の開発

    • Principal Investigator
      松居 祐樹
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Keio University
  •  Analysis of immune mechanisms and development of immunotherapy in head and neck paragangliomasPrincipal Investigator

    • Principal Investigator
      小澤 宏之
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Keio University
  •  Elucidation of antitumor effect of pimozide and clinical development for head and neck cancer

    • Principal Investigator
      中村 伸太郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Keio University
  •  PDXモデルを用いた局所進行・再発転移口腔癌に対する新たな治療戦略の考案

    • Principal Investigator
      吉川 桃子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Keio University
  •  Functional analysis of hypoxia and Hypoxia inducible factor in tumor-immune respose of head and neck cancersPrincipal Investigator

    • Principal Investigator
      Ozawa Hiroyuki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Keio University
  •  Characterization of CD44v-positive oral cancer stem cells using PDX model and establishment of novel drug therapy

    • Principal Investigator
      Yoshikawa Momoko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Keio University
  •  Development of head and neck cancer treatment targeting HIF1-alphaPrincipal Investigator

    • Principal Investigator
      OZAWA Hiroyuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Keio University
  •  AR-navigated transcanal endoscopic inner ear sugery

    • Principal Investigator
      OGAWA Kaoru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Keio University
  •  Analysis of COX-2 expression and elucidation of anticancer drug resistance mechanism in head and neck cancers

    • Principal Investigator
      WATANABE YOSHIHIRO
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Keio University
  •  Analysis of HIF1-alpa expression for head and neck cancer metastasisPrincipal Investigator

    • Principal Investigator
      Ozawa Hiroyuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Keio University
  •  頭頚部癌におけるコネキシンの発現の検討と臨床応用に関する研究Principal Investigator

    • Principal Investigator
      小澤 宏之
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      独立行政法人国立病院機構(東京医療センター臨床研究センター)

All 2019 2018 2017 2015 Other

All Journal Article Presentation

  • [Journal Article] Visualization of nerve fibers around the carotid bifurcation using a 9.4 T microscopic magnetic resonance (MR) diffusion tensor imaging with tractography.2018

    • Author(s)
      Saito S, Ozawa H, Fujioka M, Hikishima K, Hata J, Kurihara S, Okano H, Ogawa K
    • Journal Title

      Head & Neck

      Volume: ー

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19732
  • [Journal Article] 当科での経外耳道的内視鏡下耳科手術における工夫:3 hands techniqueを中心に2018

    • Author(s)
      藤岡 正人、小澤 宏之、野口 勝、粕谷 健人、石川 徹、猪狩 雄一、西山 崇経、細谷 誠、神崎 晶、大石 直樹、小川 郁
    • Journal Title

      Otology Japan

      Volume: 28(5) Pages: 659-662

    • NAID

      130007674477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19732
  • [Journal Article] Decreased Expression of Connexin-30 and Aberrant Expression of Connexin-26 in Human Head and Neck Cancer

    • Author(s)
      Hiroyuki Ozawa et al.
    • Journal Title

      Anticancer Research (in press)

    • Data Source
      KAKENHI-PROJECT-17791213
  • [Presentation] 下咽頭癌におけるANGPTL4発現の検討2019

    • Author(s)
      中原奈々 小澤宏之 関水真理子 齋藤真 吉浜圭祐 中村伸太郎 小川郁
    • Organizer
      第43回頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-17K11410
  • [Presentation] 3 hands surgeryでの経外耳道的内視鏡下耳科手術(TEES)2019

    • Author(s)
      藤岡正人,小澤宏之,野口勝,西山崇経,細谷誠,鈴木成尚,神崎晶,大石直樹,小川郁,
    • Organizer
      第120回日本耳鼻咽喉科学会総会
    • Data Source
      KAKENHI-PROJECT-17K19732
  • [Presentation] Cadaverを用いた内視鏡下耳科手術(TEES)のトレーニング2018

    • Author(s)
      藤岡正人、神崎晶、小澤宏之、大石直樹、西山崇経、野口勝、鈴木成尚、細谷誠、小川郁
    • Organizer
      第28回日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-17K19732
  • [Presentation] 頭頸部扁平上皮癌における低酸素誘導因子(HIF1-α)の機能と臨床摘意義の検討2018

    • Author(s)
      猪狩雄一、小澤宏之、今西順久、関水真理子、渡部佳弘、伊藤文展、中原奈々、齋藤真、吉浜圭祐、亀山香織、小川郁.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K11410
  • [Presentation] 内視鏡下協働手術における集合視を用いた共同注視解析2018

    • Author(s)
      塩田 智生, 伊藤 勇太, 藤岡 正人, 小澤 宏之, 戸田 正博, 杉本 麻樹,
    • Organizer
      第27回日本コンピュータ外科学会大会
    • Data Source
      KAKENHI-PROJECT-17K19732
  • [Presentation] 当科での経外耳道的内視鏡下耳科手術(TEES)2018

    • Author(s)
      藤岡正人・神崎晶・小澤宏之・大石直樹・粕谷健人・野口勝・西山崇経・石川徹・細谷誠・小川郁
    • Organizer
      第119回日本耳鼻咽喉科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-17K19732
  • [Presentation] The functional and clinicopathological analysis of hypoxia inducible factor-1α (HIF1-α) in head and neck squamous cell carcinoma2017

    • Author(s)
      Ikari Y, Ozawa H, Imanishi Y, Tomita T, Sekimizu M, Watanabe Y, Ito F, Saito S, Ogawa K
    • Organizer
      AACR annual meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11410
  • [Presentation] 当科での経外耳道的内視鏡下耳科手術における工夫:3 hands surgeryを中心に2017

    • Author(s)
      藤岡 正人・小澤宏之・神崎晶・大石直樹・粕谷健人・野口勝・西山崇経・石川徹・細谷誠・小川郁
    • Organizer
      第27回日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-17K19732
  • [Presentation] The functional and clinicopathological analysis of hypoxia inducible factor-1α (HIF1-α) in head and neck squamous cell carcinoma.2017

    • Author(s)
      Ikari Y, Ozawa H, Imanishi Y, Tomita T, Sekimizu M, Watanabe Y, Ito F, Saito S, Ogawa K
    • Organizer
      AACR annual meeting 2017
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2017-04-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462623
  • [Presentation] 頭頸部癌における同所移植転移モデルの確立とHIF1αの転移への関与について2015

    • Author(s)
      小澤宏之 伊藤文展 渡部佳弘 関水真理子 冨田俊樹 小川郁
    • Organizer
      第39頭頸部癌学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-06-04
    • Data Source
      KAKENHI-PROJECT-26462623
  • [Presentation] 頭頸部癌における同所移植転移モデルの確立とHIF1αの転移への関与について2015

    • Author(s)
      小澤宏之
    • Organizer
      第39回日本頭頸部癌学会
    • Place of Presentation
      神戸市
    • Year and Date
      2015-06-04
    • Data Source
      KAKENHI-PROJECT-26462623
  • 1.  御子柴 卓弥 (50867017)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  WATANABE Yoshihiro (30445374)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  Yoshikawa Momoko (50570967)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  莇生田 整治 (80296706)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  佐谷 秀行 (80264282)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  SATO Yoichiro (40624440)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  IMANISHI Yorihisa (80255538)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  OGAWA Kaoru (00169179)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 9.  藤岡 正人 (70398626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 10.  疋島 啓吾 (30420219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  畑 純一 (00568868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  岡野 ジェイムス洋尚 (90338020)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  中村 伸太郎 (30649976)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  岡崎 章悟 (20784044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  永井 遼斗 (70973121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  松居 祐樹 (01010636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  甲能 武幸 (90573410)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SEKIMIZU Mariko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  IKARI Yuichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SAITO Shin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  Chung Christine
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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