Mizuguchi Mineyuki 水口峰之

… Alternative Names

MIZUGUCHI Mineyuki 水口峰之

Less

Researcher Number	30332662
Other IDs
Affiliation (Current)	2025: 富山大学, 学術研究部薬学・和漢系, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 富山大学, 学術研究部薬学・和漢系, 教授 2012 – 2018: 富山大学, 大学院医学薬学研究部(薬学), 教授 2015: 富山大学, その他の研究科, 教授 2014: 富山大学, 医学薬学研究部(薬学), 教授 2013: 富山大学, その他の研究科, 教授 … More 2012 – 2013: 富山大学, 大学院医学薬学研究部, 教授 2009 – 2011: University of Toyama, 大学院・医学薬学研究部(薬学), 教授 2008 – 2011: 富山大学, 大学院・医学薬学研究部, 教授 2007 – 2008: University of Toyama, Department of Structural Biology, Assistant Professor 2007: 富山大学, 大学院・医学薬学研究部, 助教授 2006: Univ.Toyama., Fac.Pharm., Assoc.Prof., 大学院医学薬学研究部, 助教授 2005: 富山大学, 薬学部, 助教授 2004: 富山医科薬科大学, 薬学部, 助教授 2001 – 2003: 富山医科薬科大学, 薬学部, 講師 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Science and Engineering / Science and Engineering / Structural biochemistry / Biophysics Except Principal Investigator Basic Section 52020:Neurology-related / Biological Sciences / Basic Section 52010:General internal medicine-related … More / Neurology / Medical pharmacy / Structural biochemistry / Biological Sciences / Drug development chemistry Less
Keywords	Principal Investigator NMR / タンパク質 / 天然変性蛋白質 / 相互作用 / アミロイド線維 / トランスサイレチン / アミロイドβペプチド / 天然変性タンパク質 / アミロイド / アルツハイマー病 … More / フォールディング / 立体構造 / DNA結合 / cGAS / ポリグルタミン / 蛋白質 / プロリンスキャン / 中間体構造 / 家族性アミロイドポリニューロパシー / DNA結合タンパク質 / ゲルシフトアッセイ / 自然免疫 / ZCCHC3 / X線結晶構造解析 / DNA / PQBP1 / アロステリック機構 / SPR / アロステリック効果 / 表面プラズモン共鳴 / 解離定数 / 分子認識 / 生体分子 / クンパク質 / GABARAP / MAP-LC3 / 光CIDNP / 膜 / キメラ / スピンラベル / キメラタンパク質 / 中間体 / 不凍タンパク質 / Aβ / AFM / 細胞障害性 / アミロイド病 / 限定分解 / 変性蛋白質 / 安定同位体標識 / 変性中間体 / 運動性 / 疎水性コア / フォールディング中間体 / タンパク質フォールディング / 原子間力顕微鏡 / ゲルソリン / 構造安定性 / 重水素交換 / トランスシレチン / モルテングロビュール状態 / モルテングロビュール … More Except Principal Investigator アミロイドーシス / トランスサイレチン / 立体構造 / アミロイド・ブレイカー / アミロイドブレイカー / 病態モデル / 抗体治療 / OAT / oatp / 自然免疫 / タンパク質 / NMR / 蛋白質 / 昆虫 / 新型アミロイド / 老化 / 変形性膝関節症 / Drug repositioning / 薬剤スクリーニング / アミロイド / ドラッグリポジショニング / 家族性アミロイドポリニューロパチー / p-Aminohippuric acid / Estradiol 17-β glucuronide / Efflux transport / Microdialysis / Blood-retinal barrier / Oatp / dehydroepiandrosterone sulfate / estradiol 17-β glucuronide / 有機アニオン輸送担体 / p-aminohiuric acid / 免疫染色 / ρ-aminohippuric acid / estradiol17-βglucuronide / 排出輸送 / マイクロダイアリシス法 / 血液網膜関門 / invertebrate / peptide / conformational analysis / protein / innate immune system / 生体防御 / 細胞成長因子 / サイトカイン / GBP / 無脊椎動物 / ペプチド / 立体構造解析 / 生子 / 蛋白 / ＮＭＲ / 天然変性 / 質量分析 / 生体分子 / 膜受容体 / 固相スクリーニング / 膜タンパク質 / ジアジリン / リガンド結合解析 / 光アフィニティーラベル / レセプター / シグナル伝達 Less

自然免疫に重要なcGASを活性化するZCCHC3の作用機構の解明Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  University of Toyama
ATTR amyloid clearance for definitive therapy
- Principal Investigator
  
  植田光晴
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kumamoto University
Investigation of the pathogenesis and diagnostic method in knee osteoarthritis related to a novel amyloid
- Principal Investigator
  
  Tasaki Masayoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kumamoto University
How does PQBP1 suppress the induction of type I interferon expression by cGAS?Principal Investigator
- Principal Investigator
  
  Mizuguchi Mineyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  University of Toyama
Screening methods to discover ATTR amyloid disrupters
- Principal Investigator
  
  Ueda Mitsuharu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kumamoto University
Elucidation of the splicing regulatory function of an intrinsically disordered protein PQBP1Principal Investigator
- Principal Investigator
  
  Mineyuki Mizuguchi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Toyama
Novel experimental model of TTR amyloidosis using TTR fragments
- Principal Investigator
  
  Ueda Mitsuharu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kumamoto University
Verification of the connector function of the transcription and splicing factor PQBP1Principal Investigator
- Principal Investigator
  
  MIZUGUCHI Mineyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Toyama
精神遅滞関連蛋白質ＰＱＢＰ－１の揺らぎと機能の解明Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  University of Toyama
新しいタイプの天然変性蛋白質の揺らぎと機能の解明Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  University of Toyama
Characterization of structural dynamics of intrinsically disordered proteins
- Principal Investigator
  
  AKASHI Satoko
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Segmental labeling of the intrinsically disordered protein PQBP1 and elucidation of the molecular recognition mechanism by NMRPrincipal Investigator
- Principal Investigator
  
  MIZUGUCHI Mineyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Toyama
蛋白質のスローフォールディングにおける水の役割Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  University of Toyama
Development of Photoaffinity Labeling Technique for Efficient Structural Analysis of Membrane Proteins
- Principal Investigator
  
  TOMOHIRO Takenori
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
蛋白質表面における膜相互作用部位の決定方法とその応用Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Toyama
Physiological role of retina-to-blood efflux transport at the inner blood-retinal barrier
- Principal Investigator
  
  HOSOYA Kenichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
トランスサイレチンのアミロイド線維形成と立体構造変化Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
自然免疫タンパク質と受容体タンパク質およびリポ多糖との相互作用
- Principal Investigator
  
  河野敬一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
魚類由来アミロイド線維成長阻害タンパク質の作用機構Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Toyama
NMRによるアミロイドβペプチドとアミロイドβペプチド結合蛋白質の相互作用解析Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Medical and Pharmaceutical University
フォールディング開始直後のタンパク質立体構造の解明Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  University of Toyama
  Toyama Medical and Pharmaceutical University
Structural biological analysis of activation mechanism of hematocyte by ENF peptide family
- Principal Investigator
  
  KAWANO Keiichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  HOKKAIDO UNIVERSITY
NMRによるアミロイドβペプチドとトランスサイレチンの相互作用に関する研究Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Medical and Pharmaceutical University
トランスサイレチンのアミロイド形成と突然変異の効果Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Medical and Pharmaceutical University
NMRによるアミロイドβペプチドとトランスシレチンの相互作用に関する研究Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Medical and Pharmaceutical University
ヒトにも活性な昆虫成長因子GBPを受容するレセプターの蛋白質構造解析
- Principal Investigator
  
  KAWANO Keiichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Medical and Pharmaceutical University
タンパク質フォールディングに対する天然状態類似相互作用の役割のNMRによる研究Principal Investigator
- Principal Investigator
  
  水口峰之
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Toyama Medical and Pharmaceutical University

[Book] 13章天然変性タンパク質．「揺らぎ・ダイナミクスと生体機能　物理化学的視点から見た生体分子，寺嶋正秀編」2013
- Author(s)
  水口峰之，片岡幹雄
- Total Pages
  8
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-24590049
[Book] ゲノミクス・プロテオミクスの新展開 (今中忠行監修、共同執筆)2004
- Author(s)
  水口峰之, 他
- Total Pages
  1158
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-16370049
[Journal Article] Enzymatic activity of cGAS in the presence of three types of DNAs: limited cGAS stimulation by single-stranded HIV-1 SL2 DNA2024
- Author(s)
  Mizuguchi Mineyuki、Kyan Niko、Nishimata Suzuka、Nabeshima Yuko、Obita Takayuki
- Journal Title
  
  Bioscience Reports
  
  Volume: 44 Issue: 4
- DOI
  10.1042/bsr20240269
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06546
[Journal Article] Multifunctional Therapeutic Cyclodextrin-Appended Dendrimer Complex for Treatment of Systemic and Localized Amyloidosis2022
- Author(s)
  Inoue M, Higashi T, Hayashi Y, Onodera R, Fujisawa K, Taharabaru T, Yokoyama R, Ouchi K, Misumi Y, Ueda M, Inoue Y, Mizuguchi M, Saito T, Saido TC, Ando Y, Arima H, Motoyama K, Jono H.
- Journal Title
  
  ACS Appl Mater Interfaces
  
  Volume: 14 Issue: 36 Pages: 40599-40611
- DOI
  10.1021/acsami.2c09913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07528, KAKENHI-PROJECT-19K22972, KAKENHI-PROJECT-21J11627, KAKENHI-PROJECT-23K24245
[Journal Article] A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH2019
- Author(s)
  Ueda Mitsuharu、Okada Masamitsu、Mizuguchi Mineyuki、et al.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 29 Pages: 11259-11275
- DOI
  10.1074/jbc.ra119.007851
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07502, KAKENHI-PROJECT-18K08334, KAKENHI-PROJECT-19K10360, KAKENHI-PROJECT-18K18196, KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19H03565, KAKENHI-PROJECT-18K15455
[Journal Article] Allosteric modulation of the binding affinity between PQBP1 and the spliceosomal protein U5-15kD2016
- Author(s)
  Mizuguchi, M., Obita, T., Kajiyama, A., Kozakai, Y., Nakai, T., Nabeshima, Y., Okazawa, H.
- Journal Title
  
  FEBS Letters
  
  Volume: 590 Issue: 14 Pages: 2221-31
- DOI
  10.1002/1873-3468.12256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-15K07886, KAKENHI-PROJECT-16K07265
[Journal Article] Discovery of γ-Mangostin as an Amyloidogenesis Inhibitor.2015
- Author(s)
  Yokoyama T, Ueda M, Ando Y, Mizuguchi M.
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 13570-13570
- DOI
  10.1038/srep13570
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09318, KAKENHI-PROJECT-15K15195, KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-25860022
[Journal Article] Frameshift mutations in the PQBP1 gene prevent its interaction with the splicing factor U5-15kD.2015
- Author(s)
  Mizuguchi M.
- Journal Title
  
  Seikagaku
  
  Volume: 87 Pages: 478-480
- NAID
  40020571922
- Data Source
  KAKENHI-PROJECT-15K07886
[Journal Article] Segmental isotope-labeling of the intrinsically disordered protein PQBP1.2014
- Author(s)
  Nabeshima Y, Mizuguchi M, Kajiyama A, Okazawa H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 588 Issue: 24 Pages: 4583-9
- DOI
  10.1016/j.febslet.2014.10.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22110001, KAKENHI-PLANNED-22110002, KAKENHI-PROJECT-24590049, KAKENHI-PROJECT-26640037
[Journal Article] Crystal structures of human transthyretin complexed with glabridin.2014
- Author(s)
  Yokoyama T, Kosaka Y, Mizuguchi M.
- Journal Title
  
  J Med Chem.
  
  Volume: 57 Issue: 3 Pages: 1090-1096
- DOI
  10.1021/jm401832j
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-25860022
[Journal Article] Mutations in the gene PQBP1 prevent its interaction with the spliceosomal protein U5-15kD2014
- Author(s)
  Mizuguchi, M., Obita, T., Serita, T., Kojima, R., Nabeshima, Y., and Okazawa, H.
- Journal Title
  
  Nat Commun.
  
  Volume: 5 Issue: 1 Pages: 3822-3822
- DOI
  10.1038/ncomms4822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J00404, KAKENHI-PLANNED-21113003, KAKENHI-PLANNED-22110002, KAKENHI-PROJECT-24590049, KAKENHI-PROJECT-26640037, KAKENHI-PROJECT-26840018
[Journal Article] Crystallization and preliminary neutron diffraction experiment of human farnesyl pyrophosphate synthase complexed with risedronate.2014
- Author(s)
  Yokoyama T, Ostermann A, Mizuguchi M, Niimura N, Schrader TE, Tanaka I.
- Journal Title
  
  Acta Crystallogr F Struct Biol Commun.
  
  Volume: 70 Issue: 4 Pages: 470-472
- DOI
  10.1107/s2053230x14004087
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-25860022, KAKENHI-PLANNED-23108003
[Journal Article] Structural Study of Polyglutamine Tract-binding Protein 12013
- Author(s)
  Mizuguchi, M., Okazawa, H.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 133 Issue: 5 Pages: 519-526
- DOI
  10.1248/yakushi.13-00001-2
- NAID
  130003361945
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2013-05-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590049, KAKENHI-PUBLICLY-23107710
[Journal Article] Structural characterization of a trapped folding intermediate of pyrrolidone carboxyl peptidase from a hyperthermophile2012
- Author(s)
  Mizuguchi, M., Takeuchi, M., Ohki, S., Nabeshima, Y., Kouno, T., Aizawa, T., Demura, M., Kawano, K., Yutani, K.
- Journal Title
  
  Biochemistry
  
  Volume: 51 Issue: 31 Pages: 6089-6096
- DOI
  10.1021/bi300608e
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-22570166
[Journal Article] Hydrogen-bond network and pH sensitivity in transthyretin : neutron crystal structure of human transthyretin2012
- Author(s)
  Yokoyama, T., Mizuguchi, M., 他9名
- Journal Title
  
  Journal of Structural Biology
  
  Volume: 177 Issue: 2 Pages: 283-290
- DOI
  10.1016/j.jsb.2011.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-21750007, KAKENHI-PROJECT-21770159
[Journal Article] Triple bioaffinity mass spectrometry concept for thyroid transporter ligands2012
- Author(s)
  Aqai, P., Fryganas, C., Mizuguchi, M., 他2名
- Journal Title
  
  Anal Chem.
  
  Volume: 84 Issue: 15 Pages: 6488-6493
- DOI
  10.1021/ac300543u
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003
[Journal Article] Hydrogen-bondnetwork and pH sensitivity in transthyretin : neutron crystal structure of humantransthyretin2012
- Author(s)
  Yokoyama, T., Mizuguchi, M., Nabeshima, Y., Kusaka, K., Yamada, T., Hosoya, T., Ohhara, T., Kurihara, K., Tomoyori, K., Tanaka, I. and Niimura. N.
- Journal Title
  
  J Struct Biol
  
  Volume: 177 Pages: 283-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790034
[Journal Article] 天然変性タンパク質PQBP-1の揺らぎと生体機能2010
- Author(s)
  水口峰之, 岡澤均
- Journal Title
  
  メディカルバイオ
  
  Volume: 10月号別冊 Pages: 44-48
- Data Source
  KAKENHI-PUBLICLY-21107506
[Journal Article] 天然変性タンパク質PQBP-1の揺らぎと生体機能2010
- Author(s)
  水口峰之, 岡澤均
- Journal Title
  
  メディカルバイオ
  
  Volume: 10月号別冊 Pages: 44-48
- Data Source
  KAKENHI-PROJECT-21790034
[Journal Article] Polyglutamine tract-binding protein-1 binds to U5-15kD via a continuous 23-residue segment of the C-terminal domain.2010
- Author(s)
  Takahashi, M., Mizuguchi, M., et al.
- Journal Title
  
  Biochimica et Biophysica Acta-Proteins and Proteomic
  
  Volume: 1804 Pages: 1500-1507
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003
[Journal Article] 天然変性タンパク質PQBP-1の揺らぎと生体機能.メディカルバイオ2010
- Author(s)
  水口峰之, 岡澤均
- Journal Title
  
  10月号別冊「揺らぎと生体機能」
  
  Pages: 44-48
- Data Source
  KAKENHI-PROJECT-21790034
[Journal Article] Polyglutamine tract-bindingprotein-1 binds to U5-15kD via a continuous23-residue segment of the C-terminaldomain2010
- Author(s)
  Takahashi, M., Mizuguchi, M., Shinoda, H., Aizawa, T., Demura, M., Okazawa H. andKawano, K
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1804 Pages: 1500-1507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790034
[Journal Article] Polyglutamine tract binding protein-1 is an intrinsically unstructured protein.2009
- Author(s)
  Takahashi, M., Mizuguchi, M., et al.
- Journal Title
  
  Biochim.Biophys.Acta 1794
  
  Pages: 936-943
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003
[Journal Article] A novelβ-defensin structure : big defensin changes its N-terminal structureto associate with the target membrane2009
- Author(s)
  Kouno, T., Mizuguchi, M., Aizawa, T., Shinoda, H., Demura, M., Kawabata, S. andKawano, K
- Journal Title
  
  Biochemistry 48
  
  Pages: 7629-7635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790034
[Journal Article] Polyglutamine tract bindingprotein-1 is an intrinsically unstructuredprotein2009
- Author(s)
  Takahashi, M., Mizuguchi, M., Shinoda, H., Aizawa, T., Demura, M., Okazawa, H. andKawano, K
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1794 Pages: 936-943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790034
[Journal Article] Effects of the stabilization of the molten globule state on the folding mechanism of α-lactalbumin : a study of a chimera of bovine and human α-lactalbumin.2005
- Author(s)
  Mizuguchi, M., et al.
- Journal Title
  
  PROTEINS : Structure, Function, and Bioinformatics 61・2
  
  Pages: 356-365
- Data Source
  KAKENHI-PROJECT-17657037
[Journal Article] Effects of the stabilization of the molten globule state on the folding mechanism of α-lactalbumin : a study of a chimera of bovine and human α-lactalbumin.2005
- Author(s)
  Mizuguchi, M., et al.
- Journal Title
  
  PROTEINS : Structure, Function, and Bioinformatics 61・2
  
  Pages: 356-365
- Data Source
  KAKENHI-PROJECT-17028015
[Journal Article] Effects of the stabilization of the molten globule state on the folding mechanism of α-lactalbumin : A study of a chimera of bovine and human α-lactalbumin.2005
- Author(s)
  Mizuguchi, M.
- Journal Title
  
  Proteins 61(2)
  
  Pages: 356-365
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370049
[Journal Article] Effects of the stabilization of the molten globule state on the folding mechanism of α-lactalbumin : a study of a chimera of bovine and human α-lactalbumin.2005
- Author(s)
  Mizuguchi, M., et al.
- Journal Title
  
  PROTEINS : Structure, Function, and Bioinformatics 61・2
  
  Pages: 356-365
- Data Source
  KAKENHI-PROJECT-16041215
[Journal Article] Effects of the stabilization of the molten globule state on the folding mechanism of α-lactalbumin: A study of a chimera of bovine and human α-lactalbumin.2005
- Author(s)
  Mizuguchi, M.
- Journal Title
  
  Proteins 61
  
  Pages: 356-365
- Data Source
  KAKENHI-PROJECT-16370049
[Journal Article] Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains.2005
- Author(s)
  Kouno, T., Mizuguchi, M., Tanida, I., Ueno, T., Kanematsu, T., Mori, Y., Shinoda, H., Hirata, M., Kominami, E., Kawano, K.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 24610-24617
- Data Source
  KAKENHI-PROJECT-17048002
[Journal Article] Effects of the stabilization of the molten globule state on the folding mechanism of α-lactalbumin : A study of a chimera of bovine and human α-lactalbumin.2005
- Author(s)
  Mizuguchi, M.
- Journal Title
  
  Proteins 61
  
  Pages: 356-365
- Data Source
  KAKENHI-PROJECT-17048002
[Patent] アミロイドーシス治療薬の新規スクリーニング方法及びアミロイドーシスのための医薬組成物2019
- Inventor(s)
  植田光晴; 安東由喜雄; 水口峰之
- Industrial Property Rights Holder
  植田光晴; 安東由喜雄; 水口峰之
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K07502
[Presentation] Development of amyloid disruptors for ATTR amyloidosis.2020
- Author(s)
  Ueda M, Okada M, Mizuguchi M, Kluve-Beckerman B, Isoguchi A, Misumi Y, Tasaki M, Masuda T, Inoue Y, Nomura T, Obayashi K, Yamashita T, Benson M, Ando Y.
- Organizer
  XVII International Symposium on Amyloidosis.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07502
[Presentation] Role of C-terminal portion of transthyretin on amyloid formation.2016
- Author(s)
  Ueda M, Mizuguchi M, Misumi Y, Tasaki M, Suenaga G, Matsumoto S, Mizukami M, Masuda T, Yamashita T, Kluve-Beckerman B, Liepnieks JJ, Benson MD, Ando Y.
- Organizer
  The XVth International Symposium on Amyloidosis.
- Place of Presentation
  Uppsala, Sweden
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09318
[Presentation] Amyloid formation of C-terminal portion of transthyretin.2016
- Author(s)
  Ueda M, Mizuguchi M, Misumi Y, Masuda T, Tasaki M, Suenaga G, Inoue Y, Tsuda Y, Nomura T, Kinoshita Y, Matsumoto S, Mizukami M, Yamashita T, Ando Y.
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K09318
[Presentation] Interaction of spliceosomal proteins PQBP1, U5-15kD, and WBP11.2016
- Author(s)
  Mizuguchi M, Nabeshima Y, Obita T, Okazawa H.
- Organizer
  The XXVIIth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Kyoto
- Year and Date
  2016-08-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07886
[Presentation] NMRを用いた凝集性タンパク質の解析2015
- Author(s)
  水口峰之
- Organizer
  平成27年度日本分光学会ＮＭＲ分光部会
- Place of Presentation
  名古屋
- Year and Date
  2015-09-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K07886
[Presentation] セグメントラベル法によるタンパク質の重水素化2014
- Author(s)
  水口峰之
- Organizer
  平成25年度第2回生物構造学研究会タンパク質の重水素化と中性子構造生物学
- Place of Presentation
  東京
- Year and Date
  2014-03-17
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 天然変性蛋白質PQBP1のセグメント同位体標識2014
- Author(s)
  9) 鍋島裕子，水口峰之，梶山亜沙希，岡澤均
- Organizer
  日本薬学会北陸支部第126回例会
- Place of Presentation
  金沢市
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-24590049
[Presentation] セグメントラベル法によるタンパク質の重水素化2014
- Author(s)
  水口峰之
- Organizer
  平成25年度第2回生物構造学研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24590049
[Presentation] セグメントラベル法によるタンパク質の重水素化2014
- Author(s)
  水口峰之
- Organizer
  平成25年度第2回生物構造学研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 天然変性蛋白質PQBP1のセグメント同位体標識2013
- Author(s)
  水口峰之、鍋島裕子
- Organizer
  第52回NMR討論会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 天然変性蛋白質PQBP1のセグメント同位体標識2013
- Author(s)
  水口峰之，鍋島裕子
- Organizer
  第52回NMR討論会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24590049
[Presentation] 天然変性蛋白質PQBP1のセグメント標識2012
- Author(s)
  水口峰之，鍋島裕子
- Organizer
  第51回NMR討論会
- Place of Presentation
  名古屋市
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PUBLICLY-23107710
[Presentation] Structural changes of the intrinsically disordered protein PQBP-12012
- Author(s)
  Mizuguchi M.
- Organizer
  9th Japan-Korea Bilateral Symposium on Biological NMR
- Place of Presentation
  Hokkaido University
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Dynamic structural changes of the intrinsically disordered protein PQBP-12012
- Author(s)
  Mineyuki Mizuguchi
- Organizer
  4th Japan-Korea Seminar on Biomolecular Sciences, Experiments and Simulations
- Place of Presentation
  Nara
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] ポリグルタミン結合タンパク質の構造生物学的研究2012
- Author(s)
  水口峰之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(招待講演)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] 天然変性蛋白質 PQBP1 のセグメント標識2012
- Author(s)
  水口峰之、鍋島裕子
- Organizer
  第51回 NMR 討論会
- Place of Presentation
  名古屋市
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Dynamic structural changes of the intrinsically disordered protein PQBP-12012
- Author(s)
  Mizuguchi M.
- Organizer
  4th Japan-Korea Seminar on Biomolecular Sciences, Experiments and Simulations
- Place of Presentation
  Cultural Center of Todaiji-Temple
- Year and Date
  2012-01-11
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] ポリグルタミン結合タンパク質の構造生物学的研究2012
- Author(s)
  水口峰之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] Dynamic structural changes of the intrinsically disordered protein PQBP-12012
- Author(s)
  Mizuguchi M.
- Organizer
  4th Japan-Korea Seminar on Biomolecular Sciences, Experiments and Simulations
- Place of Presentation
  Cultural Center of Todaiji-Temple(招待講演)
- Year and Date
  2012-01-11
- Data Source
  KAKENHI-PUBLICLY-23107710
[Presentation] Structural changes of the intrinsically disordered protein PQBP-12012
- Author(s)
  Mizuguchi M.
- Organizer
  9th Japan-Korea Bilateral Symposium on Biological NMR
- Place of Presentation
  Hokkaido University(招待講演)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PUBLICLY-23107710
[Presentation] Structural changes of the intrinsically disordered protein PQBP-12012
- Author(s)
  Mineyuki Mizuguchi
- Organizer
  9th Japan-Korea Bilateral Symposium on Biological NMR
- Place of Presentation
  Sapporo
- Year and Date
  2012-03-16
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] ポリグルタミン結合タンパク質の構造生物学的研究2012
- Author(s)
  水口峰之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Dynamic structural changes of the intrinsically disordered protein PQBP-12012
- Author(s)
  Mizuguchi M.
- Organizer
  4th Japan-Korea Seminar on Biomolecular Sciences, Experiments and Simulations
- Place of Presentation
  Cultural Center of Todaiji-Temple(招待講演)
- Year and Date
  2012-01-11
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] Dynamic structural changesof the intrinsically disordered proteinPQBP-12012
- Author(s)
  Mizuguchi, M
- Organizer
  4th Japan-Korea Seminar onBiomolecular Sciences, Experiments andSimulations
- Place of Presentation
  Nara
- Year and Date
  2012-01-11
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] 天然変性蛋白質PQBP1のセグメント標識2012
- Author(s)
  水口峰之，鍋島裕子
- Organizer
  第51回NMR討論会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24590049
[Presentation] ポリグルタミン結合タンパク質の構造生物学的研究2012
- Author(s)
  水口峰之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Structural changes of theintrinsically disordered protein PQBP-12012
- Author(s)
  Mizuguchi, M
- Organizer
  9thJapan-Korea Bilateral Symposium onBiological NMR
- Place of Presentation
  Sapporo
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] Structural changes of the intrinsically disordered protein PQBP-12012
- Author(s)
  Mizuguchi M.
- Organizer
  9th Japan-Korea Bilateral Symposium on Biological NMR
- Place of Presentation
  Hokkaido University(招待講演)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] ポリグルタミン結合タンパク質の構造生物学的研究2012
- Author(s)
  水口峰之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(招待講演)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PUBLICLY-23107710
[Presentation] 精神遅滞の原因タンパク質PQBP-1の構造と機能2011
- Author(s)
  水口峰之
- Organizer
  第21回WSフォーラムタンパク質・ペプチド研究の現状と展望
- Place of Presentation
  九州大学(招待講演)
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PUBLICLY-23107710
[Presentation] 精神遅滞の原因タンパク質PQBP-1の構造と機能2011
- Author(s)
  水口峰之
- Organizer
  第21回WSフォーラムタンパク質・ペプチド研究の現状と展望
- Place of Presentation
  九州大学
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Dimeric transthyretin variant assembles into cytotoxic aggregates2011
- Author(s)
  Mineyuki Mizuguchi
- Organizer
  VIIIth International Symposium on Familial Amyloidotic Polyneuropathy
- Place of Presentation
  Kumamoto
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 天然変性蛋白質PQBP-1の動的な構造変化2011
- Author(s)
  水口峰之
- Organizer
  物理学会2011年秋季大会
- Place of Presentation
  富山大学
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 天然変性蛋白質PQBP-1の動的な構造変化2011
- Author(s)
  水口峰之
- Organizer
  物理学会2011年秋季大会
- Place of Presentation
  富山大学(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PUBLICLY-23107710
[Presentation] 精神遅滞の原因タンパク質PQBP-1の構造と機能2011
- Author(s)
  水口峰之
- Organizer
  第21回WSフォーラムタンパク質・ペプチド研究の現状と展望
- Place of Presentation
  福岡
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] 天然変性蛋白質PQBP-1の動的な構造変化2011
- Author(s)
  水口峰之
- Organizer
  物理学会2011年秋季大会
- Place of Presentation
  富山
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] 天然変性蛋白質PQBP-1の動的な構造変化2011
- Author(s)
  水口峰之
- Organizer
  物理学会2011年秋季大会
- Place of Presentation
  富山大学(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] 精神遅滞の原因タンパク質PQBP-1の構造と機能2011
- Author(s)
  水口峰之
- Organizer
  第21回WSフォーラムタンパク質・ペプチド研究の現状と展望
- Place of Presentation
  九州大学(招待講演)
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] Fluctuation and function ofpolyglutamine tract binding protein-12009
- Author(s)
  Mizuguchi, M., Takahashi, M., Okazawa, H. and Kawano, K
- Organizer
  The3rd International Symposium on MolecularScience of Fluctuations toward BiologicalFunctions
- Place of Presentation
  Nagoya
- Year and Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] Fluctuation and function of polyglutamine tract binding protein-1.2009
- Author(s)
  Mizuguchi, M., Takahashi, M., Okazawa, H., Kawano, K.
- Organizer
  The 3rd International Symposium on Molecular Science of Fluctuations toward Biological Functions
- Place of Presentation
  Nagoya University
- Year and Date
  2009-12-21
- Data Source
  KAKENHI-PUBLICLY-21107506
[Presentation] Fluctuation and function of polyglutamine tract binding protein-12009
- Author(s)
  Mizuguchi, M., Takahashi, M., Okazawa, H., Kawano, K.
- Organizer
  The 3rd International Symposium on Molecular Science of Fluctuations toward Biological Functions
- Place of Presentation
  Nagoya University
- Year and Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-21790034
[Presentation] Polyglutamine tract-binding protein-1由来天然変性領域の標的分子認識機構2007
- Author(s)
  高橋真樹, 水口峰之, 河野隆英, 岡澤均, 森佳洋, 篠田裕之, 河野敬一.
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター(仙台市)
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-18689002
[Presentation] 超好熱菌由来pyrrolidone carboxyl peptidaseの野生型と変異体A199Pの立体構造と変性機構の比較2007
- Author(s)
  飯村哲史, 梅嵜太郎, 坂本恵子, 岡崎伸生, 竹内誠, 水口峰之, 小笠原京子, 野田康夫, 瀬川新一, 油谷克英.
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター(仙台市)
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-18031013
[Presentation] タキプレシンIのDPCおよびLPSとの相互作用解析2007
- Author(s)
  杉田圭太郎, 神谷昌克, 大久保知行, 上島達郎, 島本怜史, 多々見文恵, 相沢智康, 水口峰之, 川端俊一郎, 出村誠, 河野敬一.
- Organizer
  第46回NMR討論会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-18689002
[Presentation] 全長pyrrolidone carboxyl peptidaseの中間体構造とC末端フラグメントの立体構造2007
- Author(s)
  竹内誠, 水口峰之, 油谷克英, 森佳洋, 篠田裕之, 河野敬一.
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター(仙台市)
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-18031013

1. OBITA Takayuki (30578696)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. Ueda Mitsuharu (60452885)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. KAWANO Keiichi (10136492)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 山中邦俊 (90212290)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. HAYAKAWA Yoichi (50164926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. DEMURA Makoto (70188704)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. AIZAWA Tomoyasu (40333596)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HATANAKA Yasumaru (30111181)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MISUMI Yohei (80625781)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. ANDO Yukio (20253742)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. Tasaki Masayoshi (50613402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. TOMOHIRO Takenori (70357581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AKASHI Satoko (10280728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SUGASE Kenji (00300822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NISHIMURA Yoshifumi (70107390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAWABATA Shun-ichiro (90183037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HOSOYA Kenichi (70301033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TACHIKAWA Masanori (00401810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMASHITA Taro (90381003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. OGURA Teru (00158825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 宮下哲 (00219776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 宮本健史 (70383768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 大林光念 (90361899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中原圭一 (60648591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 岡澤均

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Mizuguchi Mineyuki 水口 峰之

MIZUGUCHI Mineyuki 水口 峰之

Research Projects

Research Products

Co-Researchers

自然免疫に重要なcGASを活性化するZCCHC3の作用機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

How does PQBP1 suppress the induction of type I interferon expression by cGAS?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the splicing regulatory function of an intrinsically disordered protein PQBP1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Verification of the connector function of the transcription and splicing factor PQBP1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

精神遅滞関連蛋白質ＰＱＢＰ－１の揺らぎと機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新しいタイプの天然変性蛋白質の揺らぎと機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Segmental labeling of the intrinsically disordered protein PQBP1 and elucidation of the molecular recognition mechanism by NMRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

蛋白質のスローフォールディングにおける水の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Mizuguchi Mineyuki 水口峰之

MIZUGUCHI Mineyuki 水口峰之