TOMITORI Hideyuki 富取秀行

Researcher Number	30337381
Affiliation (based on the past Project Information) *help	2013: 元千葉科学大学, 薬学部, 准教授 2012: 神奈川工科大学, 応用バイオ科学部, 准教授 2011: 千葉科学大学, 薬学部, 准教授 2008 – 2010: Chiba Institute of Science, 薬学部, 講師
Review Section/Research Field	Principal Investigator Medical pharmacy Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator アクロレイン / ポリアミン / 細胞毒性 / 脳梗塞 / 臨床化学 / バイオマーカー / 脳・神経 / 生理活性物質 / 老化 / 脳機能 / ポリアミンオキシダーゼ / 薬物治療・トキシコロジー … More Except Principal Investigator … More ppGpp / 生存率 / バイオフィルム / GAPDH / グルタチオン / プトレスシン / スペルミン / スペルミジン / プトレスシン輸送 / NMDA受容体 / 脳・神経 / アクロレイン / ポリアミン / 生理活性アミン Less

アクロレインによる細胞障害の分子機構解明及び臨床応用への展開Principal Investigator
- Principal Investigator
  
  富取秀行
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanagawa Institute of Technology
Physiological role of polyamines and regulation of their cellular contents
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba Institute of Science
Research of cerebral insufficiency improver based on the mechanism of acrolein toxicity on cell growthPrincipal Investigator
- Principal Investigator
  
  TOMITORI Hideyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Chiba Institute of Science
Developmental research for measurement of acrolein and polyamine oxidase as markers for diagnosis of brain infarctionPrincipal Investigator
- Principal Investigator
  
  TOMITORI Hideyuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Chiba Institute of Science

All 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Patent

[Journal Article] Expression, purification, crystallization and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli.2013
- Author(s)
  Niiyama, M. et al.
- Journal Title
  
  Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.
  
  Volume: 69 Issue: 8 Pages: 884-887
- DOI
  10.1107/s1744309113017132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-25870126
[Journal Article] Synthesis and evaluation of pyrrole polyamide-2’-deoxyguanosine 5’-phosphate hybrid.2013
- Author(s)
  Kawashima, E., Nakanishi, Y., Terui, Y., Tomitori, H., Kashiwagi, K., Ohba, Y., and Kamaike, K.
- Journal Title
  
  Nucleosides, Nucleotides Nucleic Acids
  
  Volume: 32 Issue: 4 Pages: 196-205
- DOI
  10.1080/15257770.2013.774014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Synthesis and evaluation of pyrrole polyamide-2'-deoxyguanosine 5'-phosphate hybrid2013
- Author(s)
  Kawashima, E., Nakanishi, Y., Terui, Y., Tomitori, H., Kashiwagi, K., Ohba, Y., and Kamaike, K
- Journal Title
  
  Nucleosides, Nucleotides Nucleic Acids
  
  Volume: 32 Pages: 196-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Inactivation of GAPDH as one mechanism of acrolein toxicity2013
- Author(s)
  Nakamura, M., Tomitori, H., Suzuki, T., Sakamoto, A., Terui, Y., Saiki, R., Dohmae, N., Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 430 Pages: 1265-1271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Inactivation of GAPDH as one mechanism of acrolein toxicity.2013
- Author(s)
  Nakamura, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 430 Issue: 4 Pages: 1265-1271
- DOI
  10.1016/j.bbrc.2012.12.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Expression, purification, crystallization, and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli2013
- Author(s)
  Niiyama, M., Sugiyama, S., Hirose, M., Ishikawa, S., Tomitori, H., Higashi, K., Yamashita, T., Adachi, H., Takano, K., Murakami, S., Murata, M., Inoue, T., Mori, Y., Kashiwagi, K., Matsumura, H., and Igarashi, K
- Journal Title
  
  Acta Crystallogr
  
  Volume: F69 Pages: 884-887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli2012
- Author(s)
  Tomitori, H., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Amino Acids
  
  Volume: 42 Pages: 733-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Enhanced biofilm formation and/or cell viability by polyamines through stimulation of response regulators UvrY and CpxR in the two-component signal transducing systems, and ribosome recycling factor.2012
- Author(s)
  Sakamoto, A.
- Journal Title
  
  Int. J. Biochem. Cell Biol.
  
  Volume: 44 Issue: 11 Pages: 1877-1886
- DOI
  10.1016/j.biocel.2012.07.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24590205, KAKENHI-PROJECT-24790084
[Journal Article] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil2012
- Author(s)
  Tomitori, H., Suganami, A., Saiki, R., Mizuno, S., Yoshizawa, Y., Masuko, T., Tamura, Y., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  J. Pharmacol. Exp. Ther
  
  Volume: 343 Pages: 82-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein andωprotein of RNA polymerase in Escherichia coli2012
- Author(s)
  Terui, Y., Akiyama, M., Sakamoto, A., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Int. J. Biochem. Cell Biol
  
  Volume: 44 Pages: 412-422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Augmented glutathione synthesis decreases acrolein toxicity2012
- Author(s)
  Tomitori, H., Nakamura, M., Sakamoto, A., Terui, Y., Yoshida, M., Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 418 Pages: 110-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil.2012
- Author(s)
  Tomitori, H.
- Journal Title
  
  J. Pharmacol. Exp. Ther.
  
  Volume: 343 Issue: 1 Pages: 82-90
- DOI
  10.1124/jpet.112.192286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24590046, KAKENHI-PROJECT-24590205
[Journal Article] Enhanced biofilm formation and/or cell viability by polyamines through stimulation of response regulators UvrY and CpxR in the two-component signal transducing systems, and ribosome recycling factor2012
- Author(s)
  Sakamoto, A., Terui, Y., Yamamoto, T., Kasahara, T., Nakamura, M., Tomitori, H., Yamamoto, K., Michael, A. J., Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Int. J. Biochem. Cell Biol
  
  Volume: 44 Pages: 1877-1886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite2012
- Author(s)
  Yoshida, M., Mikami, T., Higashi, K., Saiki, R., Mizoi, M., Fukuda, K., Nakamura, T., Ishii, I., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 413 Pages: 753-759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Augmented glutathione synthesis decreases acrolein toxicity2012
- Author(s)
  Tomitori, H., et al
- Journal Title
  
  Biochem.Biophys Res.Commun.
  
  Volume: 418 Issue: 1 Pages: 110-115
- DOI
  10.1016/j.bbrc.2011.12.143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790169, KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli2012
- Author(s)
  Tomitori, H., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Amino Acids
  
  Volume: 42 Pages: 733-740
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein andωprotein of RNA polymerase in Escherichia coli2012
- Author(s)
  Terui, Y., Akiyama, M., Sakamoto, A., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K
- Journal Title
  
  Int. J. Biochem. Cell Biol.
  
  Volume: 44 Pages: 412-422
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli.2012
- Author(s)
  Tomitori, H.
- Journal Title
  
  Amino Acids
  
  Volume: 42 Issue: 2-3 Pages: 733-740
- DOI
  10.1007/s00726-011-0989-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088
[Journal Article] Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein- glutathione metabolite2012
- Author(s)
  Yoshida, M
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 413(7-8) Issue: 7-8 Pages: 753-9
- DOI
  10.1016/j.cca.2012.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590057, KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-23790076, KAKENHI-PROJECT-24590046, KAKENHI-PROJECT-24590205
[Journal Article] Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein and ω protein of RNA polymerase in Escherichia coli2012
- Author(s)
  Terui, Y., et al
- Journal Title
  
  Int.J.Biochem.Cell.Biol.
  
  Volume: 44 Issue: 2 Pages: 412-422
- DOI
  10.1016/j.biocel.2011.11.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790169, KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Augmented glutathione synthesis decreases acrolein toxicity2012
- Author(s)
  Tomitori, H., Nakamura, M., Sakamoto, A., Terui, Y., Yoshida, M., Igarashi, K., Kashiwagi, K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 418 Pages: 110-115
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Possible involvement of syntaxin 1A downregulation in the late phase of allodynia induced by peripheral nerve injury2011
- Author(s)
  Fukushima, T., Takasusuki, T., Tomitori, H., Hori, Y
- Journal Title
  
  Neuroscience
  
  Volume: 175 Pages: 344-357
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability2011
- Author(s)
  Hamdan, F. F., Gauthier, J., Araki, Y., Lin, D. T., Yoshizawa, Y., Higashi, K., Park, A. R., Spiegelman, D., Dobrzeniecka, S., Piton, A., Tomitori, H., Daoud, H., Massicotte, C., Henrion, E., Diallo, O.; S2D Group, Shekarabi, M., Marineau, C., Shevell, M.
- Journal Title
  
  Am. J. Hum. Genet
  
  Volume: 88 Pages: 306-316
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age2011
- Author(s)
  Yoshida, M., Mizoi, M., Saiki, R., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Kashiwado, K., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Tomitori, H., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 412 Pages: 339-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age2011
- Author(s)
  Yoshida, M., Mizoi, M., Saiki, R., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Kashiwado, K., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Tomitori, H., Kashiwagi, K., Igarashi, K
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 30 Pages: 339-342
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Separation of proteins using supramolecular gel electrophoresis2011
- Author(s)
  Yamamichi, S., Jinno, Y., Haraya, N., Oyoshi, T., Tomitori, H., Kashiwagi, K., and Yamanaka, M
- Journal Title
  
  Chem. Commun
  
  Volume: 47 Pages: 10344-10346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Separation of proteins using supramolecular gel electrophoresis2011
- Author(s)
  Yamamichi, S., et al
- Journal Title
  
  Chem.Commun.(Camb).
  
  Volume: 47 Issue: 37 Pages: 10344-10346
- DOI
  10.1039/c1cc13826j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790169, KAKENHI-PUBLICLY-23107514, KAKENHI-PROJECT-23590088
[Journal Article] Separation of proteins using supramolecular gel electrophoresis2011
- Author(s)
  Yamamichi, S., Jinno, Y., Haraya, N., Oyoshi, T., Tomitori, H., Kashiwagi, K., Yamanaka, M
- Journal Title
  
  Chem. Commun.(Camb)
  
  Volume: 47 Pages: 10344-10346
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Ribosome modulation factor, an important protein for cell viability encoded by the polyamine modulon2010
- Author(s)
  Terui, Y., Tabei, Y., Akiyama, M., Higashi, K., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 28698-28707
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Identification of acrolein-conjugated protein in plasma of patients with brain infarction. Biochem2010
- Author(s)
  Yoshida, M., Higashi, K., Jin, L., Machi, Y., Suzuki, T., Masuda, A., Dohmae, N., Suganami, A., Tamura, Y., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Biophys. Res. Commun. 391
  
  Pages: 1234-1239
- Data Source
  KAKENHI-PROJECT-20790143
[Journal Article] Correlation between images of silent brain infarction, carotid atherosclerosis and white matter hyperintensity, and plasma levels of acrolein, IL-6 and CRP2010
- Author(s)
  Yoshida, M., Higashi, K., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Kashiwado, K., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Machi, Y., Mizoi, M., Toida, T., Kanzaki, T., Tomitori, H., Kashiwagi, K., Igarashi, K
- Journal Title
  
  Atherosclerosis
  
  Volume: 211 Pages: 475-479
- Data Source
  KAKENHI-PROJECT-22790169
[Journal Article] Acrolein toxicity: Comparison with reactive oxygen species2009
- Author(s)
  Yoshida, M., Tomitori, H., Machi, Y., Hagihara, M., Higashi, K., Goda, H., Ohya, T., Niitsu, M., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 378
  
  Pages: 313-318
- Data Source
  KAKENHI-PROJECT-20790143
[Journal Article] Acrolein, IL-6 and CRP as markers of silent brain infarction2009
- Author(s)
  Yoshida, M., Tomitori, H., Machi, Y., Katagiri, D., Ueda, S., Horiguchi, K., Kobayashi, E., Saeki, N., Nishimura, K., Ishii, I., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Atherosclerosis 203
  
  Pages: 557-562
- Data Source
  KAKENHI-PROJECT-20790143
[Journal Article] Enhancement of the synthesis of RpoE and StpA by polyamines at the level of translation in Escherichia coli under heat shock conditions2009
- Author(s)
  Terui, Y., Higashi, K., Tabei, Y., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.
- Journal Title
  
  J. Bacteriol 191
  
  Pages: 5348-5357
- Data Source
  KAKENHI-PROJECT-20790143
[Journal Article] Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-D-aspartate receptor2008
- Author(s)
  Han, X., Tomitori, H., Mizuno, S., Higashi, K., Full, C., Fukiwake, T., Terui, Y., Leewanich, P., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J. Neurochem 107
  
  Pages: 1566-1577
- Data Source
  KAKENHI-PROJECT-20790143
[Patent] 脳卒中・無症候性脳梗塞のスクリーニングの方法2009
- Inventor(s)
  五十嵐一衛、上田志朗、佐伯直勝、柏木敬子、富取秀行
- Industrial Property Rights Holder
  株式会社アミンファーマ研究所、日油株式会社、株式会社フューエンス
- Acquisition Date
  2009-12-18
- Data Source
  KAKENHI-PROJECT-22790169
[Presentation] アクロレイン耐性細胞Neuro2a-ATD-2の毒性解除機構の解明2014
- Author(s)
  中村瑞穂, 坂本明彦, 照井祐介, 富取秀行, 斎木遼太郎, 吉田円, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第5回年会
- Place of Presentation
  銚子・千葉科学大学
- Year and Date
  2014-01-23
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] GAPDHを介したアクロレイン毒性機序の解明2013
- Author(s)
  中村瑞穂, 富取秀行, 鈴木健裕, 照井祐介, 斎木遼太郎, 堂前直, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第4回大会
- Place of Presentation
  松島・ホテル大観荘
- Year and Date
  2013-01-25
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Polyamine stimulation of eEF1A synthesis based on the unusual position of an SD-like sequence of eEF1A mRNA.2013
- Author(s)
  Sakamoto, A., Terui, Y., Kasahara, T., Yoshida, T., Tomitori, H., Igarashi, K., Kashiwagi, K.
- Organizer
  2013 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Enhanced biofilm formation and cell viability by polyamines through polyamine stimulation of response regulators UvrY and CpxR in the two-component signal transducing systems and ribosome recycling factor.2012
- Author(s)
  Sakamoto, A., Terui, Y., Yamamoto, T., Kasahara, T., Tomitori, H., Yamamoto, K., Ishihama, A., Michael, A. J., Igarashi, K., Kashiwagi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul Kultur University, Turkey
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] マウス神経芽細胞腫及びマウス乳がん細胞におけるアクロレイン毒性の解毒機構2012
- Author(s)
  富取秀行, 中村瑞穂, 坂本明彦, 照井祐介, 吉田円, 柏木敬子, 五十嵐一衛
- Organizer
  日本ポリアミン学会第3回年会
- Place of Presentation
  さいたま市民会館おおみや小ホール
- Year and Date
  2012-01-26
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil2012
- Author(s)
  Kashiwagi, K., Tomitori, H., Suganami, A., Saiki, R., Mizuno, S., Yoshizawa, Y., Masuko, T., Tamura, Y., Nishimura, K., Toida, T., Williams, K., Igarashi, K
- Organizer
  International Congress on"Polyamines : Biological and Clinical Perspectives"
- Place of Presentation
  Istanbul, Turkey, Istanbul Kültür University
- Year and Date
  2012-09-03
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミンによるバイオフィルム形成能及び生存率の上昇2012
- Author(s)
  坂本明彦, 照井祐介, 山本拓, 笠原拓馬, 富取秀行, 山本兼由, 石浜明, 五十嵐一衛, 柏木敬子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Identification and its effect on cell growth of acrolein-conjugated protein in mouse mammary carcinoma FM3A cells.2012
- Author(s)
  Tomitori, H., Nakamura, M., Suzuki, T., Terui, Y., Yoshida, M., Saiki, R., Dohmae, N., Igarashi, K., Kashiwagi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul Kultur University, Turkey
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 大腸菌ポリアミン-アミノ酸アンチポーターCadB及びPotEの構造と機能2012
- Author(s)
  富取秀行
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22790169
[Presentation] Identification and its effect on cell growth of acrolein-conjugated protein in mouse mammary carcinoma FM3A cells2012
- Author(s)
  Tomitori, H.
- Organizer
  Polyamines : Biological and Clinical Perspectives
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-24590205
[Presentation] ポリアミンによる大腸菌二成分制御系蛋白質UvrY及びCpxR合成促進に基づくバイオフィルム形成上昇2012
- Author(s)
  坂本明彦, 照井祐介, 山本拓, 笠原拓馬, 富取秀行, 山本兼由, 石浜明, 五十嵐一衛, 柏木敬子
- Organizer
  日本薬学会第132年会
- Place of Presentation
  日北海道大学高等教育推進機構
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] マウス神経芽細胞腫及びマウス乳がん細胞におけるアクロレイン毒性の解毒機構2012
- Author(s)
  富取秀行
- Organizer
  日本ポリアミン学会第3回年会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-22790169
[Presentation] マウス神経芽細胞腫及びマウス乳がん細胞におけるアクロレイン毒性の解毒機構2012
- Author(s)
  富取秀行
- Organizer
  日本ポリアミン学会第3回年会
- Place of Presentation
  さいたま市民会館、大宮
- Year and Date
  2012-01-26
- Data Source
  KAKENHI-PROJECT-22790169
[Presentation] 大腸菌ポリアミン-アミノ酸アンチポーターCadB及びPotEの構造と機能2012
- Author(s)
  富取秀行
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22790169
[Presentation] ポリアミンによるppGppの合成促進及びRpoZ-ppGpp複合体を介したRNA合成調節による大腸菌の生存率上昇.2011
- Author(s)
  坂本明彦, 照井祐介, 秋山真律子, 富取秀行, 山本兼由, 石浜明, 五十嵐一衛, 柏木敬子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Isolation and their characteristics of acrolein toxicity decreasing mutants from mouse mammary carcinoma and neuroblastoma cells2011
- Author(s)
  Tomitori, H.
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  Rhodos, Greece
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-22790169
[Presentation] Structure and functions of R domains of NMDA receptors NR1 and NR2B2011
- Author(s)
  Kashiwagi, K., Mizuno, S., Tomitori, H., Yoshizawa, Y., Han, X., Higashi, K., Saiki, R., Nishimura, K., Toida, T., Williams, K., Igarashi, K
- Organizer
  2011 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA, Waterville Valley Resort
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Structure and function of CadB and PotE2010
- Author(s)
  富取秀行
- Organizer
  2nd International Conference on the Role of Polyamines and their Analogs in cancer and other Diseases
- Place of Presentation
  Rome, Italy
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22790169
[Presentation] アクロレイン耐性細胞の樹立とその性質の検討2009
- Author(s)
  富取秀行
- Organizer
  日本ポリアミン研究会第23回研究発表会
- Place of Presentation
  藍野大学
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-20790143
[Presentation] Isolation and characterization of an acrolein tolerant mutant of FM3A cells2009
- Author(s)
  富取秀行
- Organizer
  2009 GORDON RESEARCH CONFERENCE ON POLYAMINES
- Place of Presentation
  Waterville Valley, New Hampshire, USA
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20790143
[Presentation] アクロレイン耐性細胞の樹立とその性質の検討2009
- Author(s)
  富取秀行
- Organizer
  日本ポリアミン研究会第23回研究発表会
- Place of Presentation
  藍野大学、大阪
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-20790143
[Presentation] ポリアミン酸化により産生されるアクロレインの毒性:活性酸素種との比較2009
- Author(s)
  富取秀行
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド、兵庫
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20790143
[Presentation] Polyamine effect on protein synthesis and its mechanism2009
- Author(s)
  Kashiwagi, K., Terui, Y., Higashi, K., Okudaira, H., Ochiai, E., Tomitori, H., Nishimura, K., Yamamoto, K., Ishihama, A., Igarashi, K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-20790143
[Presentation] PREDICTION OF SILENT BRAIN INFARCTION BY ACROLEIN, POLYAMINE OXIDASE2008
- Author(s)
  富取秀行
- Organizer
  IL-6 AND CRP Polyamines: Forty years of Mammalian Ornithine Decarboxylase
- Place of Presentation
  Kuopio, Finland
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-20790143
[Presentation] PREDICTION OF SILENT BRAIN INFARCTION BY ACROLEIN POLYAMINE OXIDASE, IL-6 AND CRP2008
- Author(s)
  富取秀行
- Organizer
  Polyamines : Forty years of Mammalian Ornithine Decarboxylase
- Place of Presentation
  Kuopio, Finland
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-20790143
[Presentation] アクロレイン抱合GAPDHを介したアクロレインの細胞毒性機序
- Author(s)
  中村瑞穂, 富取秀行, 鈴木健裕, 照井祐介, 斎木遼太郎, 堂前　直, 五十嵐一衛, 柏木敬子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミンによるバイオフィルム形成能及び生存率の上昇
- Author(s)
  坂本明彦, 照井祐介, 山本　拓, 笠原拓馬, 富取秀行, 山本兼由, 石浜　明, 五十嵐一衛, 柏木敬子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 真核細胞における新規ポリアミンモジュロンの同定及び蛋白質合成促進機構の解明
- Author(s)
  吉田健人, 照井祐介, 笠原拓馬, 坂本明彦, 永池　誠, 富取秀行, 五十嵐一衛, 柏木敬子
- Organizer
  「ポリアミンと核酸の共進化」第11回合同シンポジウム
- Place of Presentation
  東京慈恵会医科大学西新橋校西講堂
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 翻訳因子eIF1Aのポリアミンによる蛋白質合成促進機構の解明
- Author(s)
  笠原拓馬, 照井祐介, 吉田健人, 坂本明彦, 富取秀行, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第4回大会
- Place of Presentation
  松島・ホテル大観荘
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] アクロレイン耐性細胞Neuro2a-ATD-2の毒性解除機構の解明
- Author(s)
  中村瑞穂, 坂本明彦, 照井祐介, 富取秀行, 斎木遼太郎, 吉田　円, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第5回年会
- Place of Presentation
  銚子・千葉科学大学マリーナキャンパス
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil.
- Author(s)
  Kashiwagi, K., Tomitori, H., Suganami, A., Saiki, R., Mizuno, S., Yoshizawa, Y., Masuko, T., Tamura, Y., Nishimura, K., Toida, T., Williams, K., Igarashi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul Kultur University, Turkey
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] マウス神経芽細胞腫Neuro2a由来の新規アクロレイン耐性細胞の性質
- Author(s)
  中村瑞穂, 坂本明彦, 照井祐介, 富取秀行, 斎木遼太郎, 吉田　円, 五十嵐一衛, 柏木敬子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] スペルミンおよびイフェンプロジルの結合によるNMDA受容体GluN1及びGluN2BのN末端調節領域の構造変化
- Author(s)
  斎木遼太郎, 富取秀行, 菅波晃子, 水野聡美, 吉沢祐基, 益子　崇, 田村　裕, 西村和洋, 戸井田敏彦, キースウィリアムス, 柏木敬子, 五十嵐一衛
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] GAPDHを介したアクロレイン毒性機序の解明
- Author(s)
  中村瑞穂, 富取秀行, 鈴木健裕, 照井祐介, 斎木遼太郎, 堂前　直, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第4回大会
- Place of Presentation
  松島・ホテル大観荘
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミンによる翻訳伸長因子eIF1Aの蛋白質合成促進機構の解明
- Author(s)
  坂本明彦, 照井祐介, 吉田健人, 笠原拓馬, 富取秀行, 五十嵐一衛, 柏木敬子
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590088

1. KASHIWAGI Keiko (80169424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 33 results
2. TERUI Yusuke (60433687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results

TOMITORI Hideyuki 富取 秀行

Research Projects

Research Products

Co-Researchers

アクロレインによる細胞障害の分子機構解明及び臨床応用への展開Principal Investigator

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Physiological role of polyamines and regulation of their cellular contents

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Research of cerebral insufficiency improver based on the mechanism of acrolein toxicity on cell growthPrincipal Investigator

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Developmental research for measurement of acrolein and polyamine oxidase as markers for diagnosis of brain infarctionPrincipal Investigator

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[Journal Article] Expression, purification, crystallization and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli.2013

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[Journal Article] Synthesis and evaluation of pyrrole polyamide-2’-deoxyguanosine 5’-phosphate hybrid.2013

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[Journal Article] Synthesis and evaluation of pyrrole polyamide-2'-deoxyguanosine 5'-phosphate hybrid2013

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[Journal Article] Inactivation of GAPDH as one mechanism of acrolein toxicity2013

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[Journal Article] Inactivation of GAPDH as one mechanism of acrolein toxicity.2013

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[Journal Article] Expression, purification, crystallization, and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli2013

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[Journal Article] Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli2012

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[Journal Article] Enhanced biofilm formation and/or cell viability by polyamines through stimulation of response regulators UvrY and CpxR in the two-component signal transducing systems, and ribosome recycling factor.2012

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[Journal Article] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil2012

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[Journal Article] Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein andωprotein of RNA polymerase in Escherichia coli2012

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[Journal Article] Augmented glutathione synthesis decreases acrolein toxicity2012

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[Journal Article] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil.2012

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TOMITORI Hideyuki 富取秀行