kashiwagi keiko 柏木敬子

… Alternative Names

Researcher Number	80169424
Other IDs
Affiliation (Current)	2020: 千葉科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2005 – 2014: Chiba Institute of Science, Faculty of Pharmaceutical Sciences, Professor, 薬学部, 教授 2002 – 2005: 千葉大学, 大学院・薬学研究院, 助教授 1990 – 2000: 千葉大学, 薬学部, 助手 1988: Research Associate, 薬学部, 助手 1987: 千葉大学, 葉学部, 助手 1986: 千葉大学, 生物活性研究所, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Biological Sciences / Structural biochemistry Except Principal Investigator Biological pharmacy / Biological pharmacy / Structural biochemistry / 医薬分子機能学
Keywords	Principal Investigator ポリアミン / スペルミジン / プトレスシン / NMDA受容体 / スペルミン / ポリアミン輸送 / アンチポーター / Polyamine / Spermidine / Spermine … More Except Principal Investigator ポリアミン / スペルミン / Polyamine / Spermine / スペルミジン / NMDA受容体 / Spermidine / NMDA receptor / アンチザイム / ポリアミン輸送蛋白質 / プトレスシン / ポリアミン輸送 / Putrescine / 蛋白質合成 / 細胞増殖 / アンタゴニスト / Channel blocker / チャネルブロッカー / ビスエチルポリアミン誘導体 / 抗がん効果 / eIF5A / フレームシフト / 生体分子 / 生理活性 / 脳・神経 / バイオテクノロジー / アクロレイン / 脳梗塞 / オルニチン脱炭酸酵素 / 輸送 / ポリアミン結合部位 / Antagonist / 部位突然変異 / Site-directed mutagenesis / Mg^<2+> / アミノグリコシド / Aminoglycoside / ATP / σ^<28> / イフェンプロジル / モジュロン / RF2 / R-domain / Modulon / デオキシスパーガリン / 核酸 / グルタチオン / 細胞障害 / アルツハイマー病 / IL-6 / CRP / Aβ40/42 / GAPDH / マクロファージの泡沫化 / 3-HPMA / クローニング / 遺伝子発現調節 / ポリアミン輸送タンパク質 / クロ-ニング / polyamine / putrescine / spermidine / polyamine transport / transport gene / 5′-untranslated region / 5'-untranslated region / eIF-4E / ヘリカーゼ / Antizyme / Ornithine decarboxylase / 5'-Untranslated region / 細胞分化 / Protein synthesis / Transport / Cell proliferation / Cell differentiation / ATPase / プロテインキナーゼ / Polyamine transprt system / Polyamine binding site / アゴニスト / チャンネルブロッカー / ポリアンミン / ビスエチルポリアミン / Agonist / 部位突然異変 / 結合部位 / 活性調節 / Binding site / SD配列 / 蛋白質合成開始 / protein kinase / Polyamine transport / SD sequence / アデニレートシクラーゼ / 液胞膜 / OppA / Adenylate cyclase / Polyamine transport protein / Vacuolar membrane / 調節領域 / 難聴 / アントラキノン誘導体 / Regulatory domain / Ototoxicity / Anthraquinon derivative / σ^<38> / Frameshift / アントラキノンスペルミジン / チトクロムc / AQポリアミン / Anthraquinone spermidine / Acrolein / Stroke / 蛋白合成促進 / ポリアミン輸送蛋白 / 膜透過酵素 / polyamine transport protein / polyamine induced (PI) protein / Thymidine kinase / cell proliferation Less

Elucidation of molecular mechanism of cellular toxicity of acrolein and its clinical application
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Amine Pharma Research Institute Co., Ltd.
Physiological role of polyamines and regulation of their cellular contentsPrincipal Investigator
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba Institute of Science
Structure and functions of polyamine transport proteins and NMDA receptorsPrincipal Investigator
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba Institute of Science
Elucidation of function of polyamines and regulation of their contents in cells
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Molecular mechanism and physiological role of polyamine transport systems and NMDA receptorsPrincipal Investigator
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba Institute of Science
Regulation of cell growth and brain function by polyamines
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Structure and function of polyamine transport systems and NMDA receptorsPrincipal Investigator
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba Institute of Science
  Chiba University
聴覚障害を惹起しないアミノグリコシド系抗菌薬とVNC細菌に作用する抗菌薬の開発Principal Investigator
- Principal Investigator
  
  柏木敬子
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Modulation of cellular functions by polyamines through polyamine interaction with RNA and proteins
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Characterization of polyamine transport systems and modulation of NMDA receptor by polyaminesPrincipal Investigator
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Polyamines as biomodulators - regulation of their contents and their physiological functions
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Polyamines as biomodulators - regulation of their contents and their physiological functions
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
ポリアミン代謝拮抗に基づく抗がん剤の分子設計
- Principal Investigator
  
  五十嵐一衛
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
ポリアミン輸送系とNMDA受容体の構造・機能協関Principal Investigator
- Principal Investigator
  
  柏木敬子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Regulation of glutamate receptors by polyamines
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Regulation of polyamine contents in cells and their physiological functions
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Characteristics of polyamine transport and regulation of its gene expressionPrincipal Investigator
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
ビスエチルポリアミン誘導体の抗がん効果
- Principal Investigator
  
  五十嵐一衛
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Regulation of NMDA receptor by polyamine and its derivatives
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Regulation of polyamine contents in cells and their effects on protein synthesis
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Search for polyamine agonists and antagonists acting on NMDA receptor.
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Chiba University
Regulation of polyamine contents in cellsPrincipal Investigator
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Chiba University
ビスエチルポリアミン誘導体の抗がん効果
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Role of polyamines on cell proliferation and differentiation
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
環境ストレス応答におけるポリアミンの役割Principal Investigator
- Principal Investigator
  
  柏木敬子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Physiological functions of polyamines and its transport
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Chiba University
Properties of polyamine transport proteins and their genesPrincipal Investigator
- Principal Investigator
  
  KASHIWAGI Keiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Cloning of the genes for polyamine transport proteins and regulation of its expression
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
Molecular mechanism of polyamine effect on cell proliferation
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University

All 2014 2013 2012 2011 2010 2009 2008 2007 2004 Other

All Journal Article Presentation Book Patent

[Book] Methods Mol.Biol. 720(Eds. A.E. Pegg and R.A. Casero, Jr)(Characterization of genes for polyamine modulon. "Polyamines")2011
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Total Pages
  523
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20590066
[Book] Methods Mol.Biol. 720(Eds. A.E. Pegg and R.A. Casero, Jr)(Use of polyamine metabolites as markers for stroke and renal failure. "Polyamines")2011
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Total Pages
  523
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20590066
[Book] Methods Mol.Biol. 720(Eds. A.E. Pegg and R.A. Casero, Jr)(Identification and assays of polyamine transport systems in Escherichia coli and Saccharomyces cerevisiae. "Polyamines")2011
- Author(s)
  Kashiwagi, K., Igarashi, K.
- Total Pages
  523
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Distinction between mild cognitive impairment and Alzheimer's disease2014
- Author(s)
  Mizoi, M. et al.
- Journal Title
  
  Clin Chim Acta
  
  Volume: 430 Pages: 150-155
- DOI
  10.1016/j.cca.2014.01.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24591695
[Journal Article] Properties of putrescine uptake by PotFGHI and PuuP and their physiological significance in Escherichia coli2014
- Author(s)
  Terui, Y., Saroj, S. D., Sakamoto, A., Yoshida, T., Higashi, K., Kurihara, S., Suzuki, H., Toida, T., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Amino Acids
  
  Volume: 46 Pages: 661-670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Distinction between mild cognitive impairment and Alzhemer's disease by CSF amyloidβ40 andβ42, and protein-conjugated acrolein2014
- Author(s)
  Mizoi, M., Yoshida, M., Saiki, R., Waragai, M., Uemura, K., Akatsu, H., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 430 Pages: 150-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Properties of putrescine uptake by PotFGHI and PuuP and their physiological significance in Escherichia coli2014
- Author(s)
  Terui, Y. et al.
- Journal Title
  
  Amino Acids
  
  Volume: 46 Pages: 999-1004
- DOI
  10.1007/s00726-013-1517-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-23658079, KAKENHI-PROJECT-24590046, KAKENHI-PROJECT-24790084, KAKENHI-PROJECT-25870126
[Journal Article] In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers.2013
- Author(s)
  Saiki, R. et al.
- Journal Title
  
  Bioorgnic Medicinal Chemistry Letter
  
  Volume: 23 Pages: 3901-1904
- DOI
  10.1016/j.bmcl.2013.04.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24590046
[Journal Article] Spermidine is required for morphogenesis in the human pathogenic fungus, Penicillium marneffei2013
- Author(s)
  Kummasook, A., Cooper, C. R. Jr., Sakamoto, A., Terui, Y., Kashiwagi, K., and Vanittanakorn, N
- Journal Title
  
  Fungal Genet. Biol
  
  Volume: 58-59 Pages: 25-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Synthesis and Evaluation of Pyrrole Polyamide- 2′-Deoxyguanosine 5′-Phosphate Hybrid2013
- Author(s)
  Kawashima, E., Nakanishi, Y., Terui, Y., Tomitori, H., Kashiwagi, K., Ohba, Y., and Kamaike, K.
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 32 Pages: 196-205
- DOI
  10.1080/15257770.2013.774014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Prediction of the interaction between apermidine and the G-G mismatch containing acceptor stem in tRNA(IIe): molecular modeling, density functional theory, and molecular dynamic study2013
- Author(s)
  Hayashi, Y. et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 441 Pages: 999-1004
- DOI
  10.1016/j.bbrc.2013.11.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-25460328, KAKENHI-PROJECT-25462244, KAKENHI-PROJECT-25870126
[Journal Article] In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers2013
- Author(s)
  Saiki, R., Yoshizawa, Y., Minarini, A., Milelli, A., Marchetti, C., Tumiatti, V., Toida, T., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 23 Pages: 3901-3904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle.2013
- Author(s)
  Yamashita, T. et al.
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: 45 Pages: 1042-1050
- DOI
  10.1016/j.biocel.2013.02.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-23790076, KAKENHI-PROJECT-24790084, KAKENHI-PROJECT-25870126
[Journal Article] Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle2013
- Author(s)
  Yamashita, T., Nishimura, K., Saiki, R., Okudaira, H., Tome, M., Higashi, K., Nakamura, M., Terui, Y., Fujiwara, K., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Int. J. Biochem. Cell Biol
  
  Volume: 45 Pages: 1042-1050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Expression, purification, crystallization, and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli2013
- Author(s)
  Niiyama, M., Sugiyama, S., Hirose, M., Ishikawa, S., Tomitori, H., Higashi, K., Yamashita, T., Adachi, H., Takano, K., Murakami, S., Murata, M., Inoue, T., Mori, Y., Kashiwagi, K., Matsumura, H., and Igarashi, K
- Journal Title
  
  Acta Crystallogr
  
  Volume: F69 Pages: 884-887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Inactivation of GAPDH as one mechanism of acrolein toxicity.2013
- Author(s)
  Nakamura, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 430 Pages: 1265-1271
- DOI
  10.1016/j.bbrc.2012.12.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Inactivation of GAPDH as one mechanism of acrolein toxicity2013
- Author(s)
  Nakamura, M., Tomitori, H., Suzuki, T., Sakamoto, A., Terui, Y., Saiki, R., Dohmae, N., Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 430 Pages: 1265-1271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Synthesis and evaluation of pyrrole polyamide-2'-deoxyguanosine 5'-phosphate hybrid2013
- Author(s)
  Kawashima, E., Nakanishi, Y., Terui, Y., Tomitori, H., Kashiwagi, K., Ohba, Y., and Kamaike, K
- Journal Title
  
  Nucleosides, Nucleotides Nucleic Acids
  
  Volume: 32 Pages: 196-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Acrolein stimulates the synthesis of IL-6 and CRP in thrombosis model mice and cultured cells2013
- Author(s)
  Saiki, R., Hayashi, D., Ikuo, Y., Nishimura, K., Ishii, I., Kobayashi, K., Chiba, K., Toida, T., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  J. Neurochem
  
  Volume: 127 Pages: 652-659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Expression, purification, crystallization and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli2013
- Author(s)
  Niiyama, M. et al.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun
  
  Volume: 69 Pages: 884-887
- DOI
  10.1107/s1744309113017132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-25870126
[Journal Article] Spermidine is required for morphogenesis in the human pathogenic fungus, Penicillium marneffei.2013
- Author(s)
  Kummasook, A., Cooper, C. R. Jr., Sakamoto, A., Terui, Y., Kashiwagi, K., and Vanittanakorn, N.
- Journal Title
  
  Fungal Genetics and Biology
  
  Volume: 58-59 Pages: 25-32
- DOI
  10.1016/j.fgb.2013.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Prediction of the interaction between spermidine and G-G mismatch containing acceptor stem in tRNA^<Ile>: Molecular modeling, density functional theory, and molecular dynamics study2013
- Author(s)
  Hayashi, Y., Sugiyama, H., Suganami, A., Higashi, K., Kashiwagi, K., Igarashi, K., and Kawauchi, S
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 441 (4) Pages: 999-1004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Acrolein stimulates the synthesis of IL-6 and C-reactive protein (CRP) in thrombosis model mice and cultured cells.2013
- Author(s)
  Saiki, R. et al.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 127 Pages: 652-659
- DOI
  10.1111/jnc.12336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24590046
[Journal Article] Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil.2012
- Author(s)
  Tomitori, H.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 343 Pages: 82-90
- DOI
  10.1124/jpet.112.192286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24590046, KAKENHI-PROJECT-24590205
[Journal Article] Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite.2012
- Author(s)
  Yoshida, M
- Journal Title
  
  Clin. Chim. Acta.
  
  Volume: 413(7-8) Pages: 753-759
- DOI
  10.1016/j.cca.2012.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590057, KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-23790076, KAKENHI-PROJECT-24590046, KAKENHI-PROJECT-24590205
[Journal Article] Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo.2012
- Author(s)
  Takashi Masuko, Toyofumi Suzuki, et al
- Journal Title
  
  Neurosci Lett.
  
  Volume: 506 Pages: 251-255
- DOI
  10.1016/j.neulet.2011.11.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590149, KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088
[Journal Article] Enhanced biofilm formation and/or cell viability by polyamines through stimulation of response regulators UvrY and CpxR in the two-component signal transducing systems, and ribosome recycling factor2012
- Author(s)
  Sakamoto, A., Terui, Y., Yamamoto, T., Kasahara, T., Nakamura, M., Tomitori, H., Yamamoto, K., Michael, A. J., Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Int. J. Biochem. Cell Biol
  
  Volume: 44 Pages: 1877-1886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive2012
- Author(s)
  Waragai, M.
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 32 Pages: 33-41
- DOI
  10.3233/jad-2012-120253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24591695
[Journal Article] Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite2012
- Author(s)
  Yoshida, M., Mikami, T., Higashi, K., Saiki, R., Mizoi, M., Fukuda, K., Nakamura, T., Ishii, I., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 413 Pages: 753-759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive impairment and Alzheimer's disease2012
- Author(s)
  Waragai, M., Yoshida, M., Mizoi, M., Saiki, R., Kashiwagi, K., Takagi, K., Arai, H., Tashiro, J., Hashimoto, M., Iwai, N., Uemura, K., and Igarashi, K
- Journal Title
  
  J. Alzheimer's Dis
  
  Volume: 32 Pages: 33-411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo2012
- Author(s)
  Masuko, T., Suzuki, T., Miyake, M., Kusama-Eguchi, K., Kizawa, Y., Tomono, K., Kashiwagi, K., Igarashi, K., Kusama, T
- Journal Title
  
  Neurosci Lett
  
  Volume: 506 Pages: 251-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil2012
- Author(s)
  Tomitori, H., Suganami, A., Saiki, R., Mizuno, S., Yoshizawa, Y., Masuko, T., Tamura, Y., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  J. Pharmacol. Exp. Ther
  
  Volume: 343 Pages: 82-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein andωprotein of RNA polymerase in Escherichia coli2012
- Author(s)
  Terui, Y., Akiyama, M., Sakamoto, A., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Int. J. Biochem. Cell Biol
  
  Volume: 44 Pages: 412-422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Enhanced biofilm formation and/or cell viability by polyamines through stimulation of response regulators UvrY and CpxR in the two-component signal transducing systems, and ribosome recycling factor.2012
- Author(s)
  Sakamoto, A.
- Journal Title
  
  Int. J. Biochem. Cell Biol.
  
  Volume: 44 Pages: 1877-1886
- DOI
  10.1016/j.biocel.2012.07.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24590205, KAKENHI-PROJECT-24790084
[Journal Article] Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein and ω protein of RNA polymerase in Escherichia coli.2012
- Author(s)
  Terui, Y., et al
- Journal Title
  
  Int. J. Biochem. Cell Biol.
  
  Volume: 44 Pages: 412-422
- DOI
  10.1016/j.biocel.2011.11.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790169, KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli.2012
- Author(s)
  Tomitori, H.
- Journal Title
  
  Amino Acids
  
  Volume: 42 Pages: 733-740
- DOI
  10.1007/s00726-011-0989-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088
[Journal Article] Augmented glutathione synthesis decreases acrolein toxicity.2012
- Author(s)
  Tomitori, H., et al
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 418 Pages: 110-115
- DOI
  10.1016/j.bbrc.2011.12.143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790169, KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24790084
[Journal Article] Augmented glutathione synthesis decreases acrolein toxicity2012
- Author(s)
  Tomitori, H., Nakamura, M., Sakamoto, A., Terui, Y., Yoshida, M., Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 418 Pages: 110-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli2012
- Author(s)
  Tomitori, H., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Amino Acids
  
  Volume: 42 Pages: 733-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Protein-conjugated acrolein as a biochemical marker of brain infarction.2011
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Nutr. Food Res.
  
  Volume: 55(Review article) Pages: 1332-1341
- DOI
  10.1002/mnfr.201100068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088
[Journal Article] Separation of proteins using supramolecular gel electrophoresis2011
- Author(s)
  Yamamichi, S., Jinno, Y., Haraya, N., Oyoshi, T., Tomitori, H., Kashiwagi, K., and Yamanaka, M
- Journal Title
  
  Chem. Commun
  
  Volume: 47 Pages: 10344-10346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Brain infarction correlates more closely with acrolein than with reactive oxygen species.2011
- Author(s)
  Saiki, R., Park, H., Ishii, I., Yoshida, M., Nishimura, K., Toida, T., Tatsukawa, H., Kojima, S., Ikeguchi, Y., Pegg, A.E., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 404
  
  Pages: 1044-1049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Characterization of genes for polyamine modulon.2011
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 720(Review article) Pages: 51-65
- DOI
  10.1007/978-1-61779-034-8_3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088
[Journal Article] Use of polyamine metabolites as markers for stroke and renal failure2011
- Author(s)
  Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Methods Mol. Biol
  
  Volume: 720 Pages: 395-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Identification and assays of polyamine transport systems in Escherichia coli and Saccharomyces cerevisiae.2011
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 720(Review article) Pages: 295-308
- DOI
  10.1007/978-1-61779-034-8_18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088
[Journal Article] Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age.2011
- Author(s)
  Yoshida, M., Mizoi, M., Saiki, R., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Kashiwado, K., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Tomitori, H., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Clin.Chim.Acta 412
  
  Pages: 339-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age2011
- Author(s)
  Yoshida, M., Mizoi, M., Saiki, R., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Kashiwado, K., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Tomitori, H., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 412 Pages: 339-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Protein-conjugated acrolein as a biochemical marker of brain infarction2011
- Author(s)
  Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Mol. Nutr. Food Res
  
  Volume: 55 Pages: 1332-1341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Separation of proteins using supramolecular gel electrophoresis.2011
- Author(s)
  Yamamichi, S., et al
- Journal Title
  
  Chem. Commun.
  
  Volume: 47 Pages: 10344-10346
- DOI
  10.1039/c1cc13826j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790169, KAKENHI-PUBLICLY-23107514, KAKENHI-PROJECT-23590088
[Journal Article] Use of polyamine metabolites as markers for stroke and renal failure.2011
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 720(Review article) Pages: 395-408
- DOI
  10.1007/978-1-61779-034-8_25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088
[Journal Article] Brain infarction correlates more closely with acrolein than with reactive oxygen species2011
- Author(s)
  Saiki, R., Park, H., Ishii, I., Yoshida, M., Nishimura, K., Toida, T., Tatsukawa, H., Kojima, S., Ikeguchi, Y., Pegg, A. E., Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 404 Pages: 1044-1049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Identification and assays of polyamine transport systems in Escherichia coli and Saccharomyces cerevisiae2011
- Author(s)
  Kashiwagi, K., and Igarashi, K
- Journal Title
  
  Methods Mol. Biol
  
  Volume: 720 Pages: 295-308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Characterization of genes for polyamine modulon2011
- Author(s)
  Igarashi, K., and Kashiwagi, K
- Journal Title
  
  Methods Mol. Biol
  
  Volume: 720 Pages: 51-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590088
[Journal Article] Intense correlation between protein-conjugated acrolein and primary Sjogren's syndrome2010
- Author(s)
  Higashi, K., Yoshida, M., Igarashi, A., Ito, K., Wada, Y., Murakami, S., Kobayashi, D., Nakano, M., Sohda, M., Nakajima, T., Narita, I., Toida, T., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Clin.Chim.Acta 41
  
  Pages: 359-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Identification of acrolein-conjugated protein in plasma of patients with brain infarction2010
- Author(s)
  Yoshida, M., Higashi, K., Jin, L., Machi, Y., Suzuki, T., Masuda, A., Dohmae, N., Suganami, A., Tamura, Y., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 391
  
  Pages: 1234-1239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Identification and functions of amino acid residues in PotB and PotC involved in spermidine uptake activity.2010
- Author(s)
  Higashi, K., Sakamaki, Y., Herai, E., Demizu, R., Uemura, T.m Saroj, S.D., Terui, Y., Nishimura, K., Toida, T., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 39061-39069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Modulation of cellular function by polyamines.(Review article)2010
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 42
  
  Pages: 39-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Modulation of cellular function by polyamines. (Review article)2010
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 42
  
  Pages: 39-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Correlation between images of silent brain infarction, carotid atherosclerosis and white matter hyperintensity, and plasma levels of acrolein, IL-6 and CRP.2010
- Author(s)
  Yoshida, M., Higashi, K., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Machi, Y., Mizoi, M., Toida, T., Kanzaki, T., Tomitori, H., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Atherosclerosis 211
  
  Pages: 475-479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Characteristics of cellular polyamine transport in prokaryotes and eukaryotes.2010
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Plant Physiol.Biochem.
  
  Volume: 48 Pages: 506-512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Characteristics of cellular polyamine transport in prokaryotes and eukaryotes.(Review article)2010
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Plant Physiol.Biochem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Intense correlation between protein-conjugated acrolein and primary Sjogren's syndrome.2010
- Author(s)
  Higashi, K., Yoshida, M., Igarashi, A., Ito, K., Wada, Y., Murakami, S., Kobayashi, D., Nakano, M., Sohda, M., Nakajima, T., Narita, I., Toida, T., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Clin.Chim.Acta 411
  
  Pages: 359-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Ribosome modulation factor, an important protein for cell viability encoded by the polyamine modulon.2010
- Author(s)
  Terui, Y., Tabei, Y., Akiyama, M., Higashi, K., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 28698-28707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Modulation of cellular function by polyamines2010
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 42
  
  Pages: 39-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Modulation of cellular function by polyamines.2010
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol.
  
  Volume: 42 Pages: 39-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Identification of acrolein-conjugated protein in plasma of patients with brain infarction.2010
- Author(s)
  Yoshida, M., Higashi, K., Jin, L., Machi, Y., Suzuki, T., Masuda, A., Dohmae, N., Suganami, A., Tamura, Y., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 391
  
  Pages: 1234-1239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Characteristics of cellular polyamine transport in prokaryotes and eukaryotes. (Review article)2010
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Plant Physiol.Biochem. 48
  
  Pages: 506-512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Polyamine-modulon in yeast-stimulation of COX4 synthesis by spermidine at the level of translation.2009
- Author(s)
  Uemura, T., Higashi, K., Takigawa, M., Toida, T., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 41
  
  Pages: 2538-2545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Identification of proteins whose synthesis is preferentially enhanced by polyamines at the level of translation in mammalian cells2009
- Author(s)
  Nishimura, K., Okudaira, H., Ochiai, E., Higashi, K., Kaneko, M., Ishii, I., Nishimura, T., Dohmae, N., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 41
  
  Pages: 2251-2261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Enhancement of the synthesis of RpoE and StpA by polyamines at the level of translation in Escherichia coli under heat shock conditions.2009
- Author(s)
  Terui, Y., Higashi, K., Tabei, Y., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.
- Journal Title
  
  J.Bacteriol. 191
  
  Pages: 5348-5357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Intense correlation between brain infarction and protein-conjugated acrolein.2009
- Author(s)
  Saiki, R., Nishimura, K., Ishii, I., Omura, T., Okuyama, S., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Stroke 40
  
  Pages: 3356-3361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Acrolein, IL-6 and CRP as markers of silent brain infarction2009
- Author(s)
  Yoshida, M., Tomitori, H., Machi, Y., Katagiri, D., Ueda, S., Horiguchi, K., Kobayashi, E., Saeki, N., Nishimura, K., Ishii, I., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Atherosclerosis 203
  
  Pages: 557-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Acrolein toxicity : comparison with reactive oxygen species2009
- Author(s)
  Yoshida, M., Tomitori, H., Machi, Y., Hagihara, M., Higashi, K., Goda, H., Ohya, T., Niitsu, M., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 378
  
  Pages: 313-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Identification of proteins whose synthesis is preferentially enhanced by polyamines at the level of translation in mammalian cells.2009
- Author(s)
  Nishimura, K., Okudaira, H., Ochiai, E., Higashi, K., Kaneko, M., Ishii, I., Nishimura, T., Dohmae, N., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 41
  
  Pages: 2251-2261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Enhancement of the synthesis of RpoE and StpA by polyamines at the level of translation in Escherichia coli under heat shock conditions2009
- Author(s)
  Terui, Y., Higashi, K., Tabei, Y., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.
- Journal Title
  
  J.Bacteriol. 191
  
  Pages: 5348-5357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.2009
- Author(s)
  Masuko, T., Namiki, R., Nemoto, Y., Miyake, M., Kizawa, Y., Suzuki, T., Kashiwagi, K., Igarashi, K., Kusama, T.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 331
  
  Pages: 522-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Acrolein, IL-6 and CRP as markers of silent brain infarction.2009
- Author(s)
  Yoshida, M., Tomitori, H., Machi, Y., Katagiri, D., Ueda, S., Horiguchi, K., Kobayashi, E., Saeki, N., Nishimura, K., Ishii, I., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Atherosclerosis 203
  
  Pages: 557-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Polyamine-modulon in yeast―stimulation of COX4 synthesis by spermidine at the level of translation2009
- Author(s)
  Uemura, T., Higashi, K., Takigawa, M., Toida, T., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 41
  
  Pages: 2538-2545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Intense correlation between brain infarction and protein-conjugated acrolein2009
- Author(s)
  Saiki, R., Nishimura, K., Ishii, I., Omura, T., Okuyama, S., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Stroke 40
  
  Pages: 3356-3361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Acrolein toxicity : comparison with reactive oxygen species.2009
- Author(s)
  Yoshida, M., Tomitori, H., Machi, Y., Hagihara, M., Higashi, K., Goda, H., Ohya, T., Niitsu, M., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 378
  
  Pages: 313-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] The pore region of N-methyl-D-aspartate receptors differentially influences stimulation and block by spermine2008
- Author(s)
  Jin, L., Miyazaki, M., Mizuno, S., Takigawa, M., Hirose, T., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 327
  
  Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] The pore region of N-methyl-D-aspartate receptors differentially influences stimulation and block by spermine.2008
- Author(s)
  Jin, L., Miyazaki, M., Mizuno, S., Takigawa, M., Hirose, T., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 327
  
  Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-D-aspartate receptor.2008
- Author(s)
  Han, X., Tomitori, H., Mizuno, S., Higashi, K., Full, C., Fukiwake, T., Terui, Y., Leewanich, P., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Neurochem. 107
  
  Pages: 1566-1577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Differential effects of linear and cyclic polyamines on NMDA receptor activities.2008
- Author(s)
  Masuko, T., Miyake, M., Kusama-Eguchi, K., Koike, T., Kimura, E., Kizawa, Y., Kashiwagi, K., Igarashi, K., Kusama, T.
- Journal Title
  
  Neurochem.Int. 53
  
  Pages: 38-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-Daspartate receptor2008
- Author(s)
  Han, X., Tomitori, H., Mizuno, S., Higashi, K., Full, C., Fukiwake, T., Terui, Y., Leewanich, P., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Neurochem. 107
  
  Pages: 1566-1577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Selective structural change of bulged-out region of double-stranded RNA containing bulged nucleotides by spermidine.2008
- Author(s)
  Higashi, K., Terui, Y., Inomata, E., Katagiri, D., Nomura, Y., Someya, T., Nishimura, K., Kashiwagi, K., Kawai, G., Igarashi, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 370
  
  Pages: 572-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Selective structural change by spermidine in the bulged-out region of double-stranded RNA and its effect on RNA function.2008
- Author(s)
  Higashi, K., Terui, Y., Suganami, A., Tamura, Y., Nishimura, K., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 32989-32994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli2008
- Author(s)
  Higashi, K., Ishigure, H., Demizu, R., Uemura, T., Nishino, K., Yamaguchi, A., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Bacteriol. 190
  
  Pages: 872-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Selective structural change of bulged-out region of double-stranded RNA containing bulged nucleotides by spermidine2008
- Author(s)
  Higashi, K., Terui, Y., Inomata, E., Katagiri, D., Nomura, Y., Someya, T., Nishimura, K., Kashiwagi, K., Kawai, G., Igarashi, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 370
  
  Pages: 572-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Selective structural change by spermidine of the bulged-out region of double-stranded RNA and its effect on RNA function2008
- Author(s)
  Higashi, K., Terui, Y., Suganami, A., Tamura, Y., Nishimura, K., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 32989-32994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.2008
- Author(s)
  Higashi, K., Ishigure, H., Demizu, R., Uemura, T., Nishino, K., Yamaguchi, A., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Bacteriol. 190
  
  Pages: 872-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590066
[Journal Article] Anthraquinone polyamines : novel channel blockers on N-methyl-D-aspartate receptors2007
- Author(s)
  Kashiwagi, K., et. al.
- Journal Title
  
  Amino Acids 33
  
  Pages: 299-304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590069
[Journal Article] Anthraquinone polyamines : novel channel blockers of N-methyl-D-aspartate receptors2007
- Author(s)
  Kashiwagi, K., Williams, K., Igarashi, K.
- Journal Title
  
  Amino Acids 33
  
  Pages: 299-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Enhancement of the synthesis of RpoN, Cra and H-NS by polyamines at the level of translation in Escherichia coli cultured with glucose and glutamate2007
- Author(s)
  Terui, Y., Higashi, K., Taniguchi, S., Shigemasa, A., Nishimura, K., Yamamoto, K., Kashiwagi, K., Ishihama, A., Igarashi, K.
- Journal Title
  
  J.Bacteriol. 189
  
  Pages: 2359-2368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Polyamine uptake by DUR3 and SAM3 in Saccharomyces cerevisiae2007
- Author(s)
  Uemura, T., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 7733-7741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Comparative studies of anthraquinone-and anthracenetetraamines as blockers of N-methyl-D-aspartate receptors2007
- Author(s)
  Jin, L., Sugiyama, H., Takigawa, M., Katagiri, D., Tomitori, H., Nishimura, K., Kaur, N., Phanstiel IV, O., Kitajima, M., Takayama, H., Okawara, T., Williams, K., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 320
  
  Pages: 47-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Minor contribution of an internal ribosome entry site in the 5'-UTR of ornithine decarboxylase mRNA on its translation2007
- Author(s)
  Nishimura, K., Sakuma, A., Yamashita, T., Hirokawa, G., Imataka, H., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 364
  
  Pages: 124-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Anthraquinone polyamines:novel channel blockers on N-methyl-D-aspartate receptors2007
- Author(s)
  Kashiwagi, K., et. al.
- Journal Title
  
  Amino Acids 33
  
  Pages: 299-304
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590069
[Journal Article] Anthraquinone polyamines : Novel channel blockers to study NMDA receptors2004
- Author(s)
  Kashiwagi, K., et al.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 309
  
  Pages: 884-893
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590042
[Journal Article] Anthraquinone polyamines : Novel channel blockers to study NMDA receptors2004
- Author(s)
  Kashiwagi, K, et al.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 309
  
  Pages: 884-893
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590042
[Journal Article] Anthraquinone polyamines : Novel channel blockers to study NMDA receptors2004
- Author(s)
  Kashiwagi, K., et al.
- Journal Title
  
  J. Pharmacol. EXP. Ther. 309
  
  Pages: 884-893
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390018
[Journal Article] Anthraquinone polyamines : Novel channel blockers to study NMDA receptors.2004
- Author(s)
  Kashiwagi, K. et al.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 309
  
  Pages: 884-893
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390018
[Journal Article] Anthraquinone polyamines : Novel channel blockers to study NMDA receptors.2004
- Author(s)
  Kashiwagi, K. et al.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 309
  
  Pages: 884-893
- Data Source
  KAKENHI-PROJECT-16590042
[Journal Article] Characteristics of cellular polyamine transport in prokaryotes and eukaryotes
- Author(s)
  Igarashi, K., Kashiwagi, K.
- Journal Title
  
  Plant Physiol.Biochem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Patent] 3-HPMAを指標とした脳卒中及び/又は脳梗塞の判定方法2012
- Inventor(s)
  五十嵐一衛、柏木敬子、吉田円、溝井睦美、斎木遼太郎
- Industrial Property Rights Holder
  株式会社アミンファーマ研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-12
- Data Source
  KAKENHI-PROJECT-23590088
[Patent] 3-HPMAを指標とした脳卒中及び/又は脳梗塞の判定方法2012
- Inventor(s)
  五十嵐一衛、柏木敬子、吉田円、溝井睦美、斎木遼太郎
- Industrial Property Rights Holder
  株式会社アミンファーマ研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-11
- Data Source
  KAKENHI-PROJECT-23390038
[Presentation] Isolation of two kinds of acrolein toxicity decreasing mutants of Neuro2a cells.2014
- Author(s)
  Kashiwagi, K. et al.
- Organizer
  Third International Conference on Polyamines: Biochemical, Physiological and Clinical Perspectives
- Place of Presentation
  Ubatuba-SP, Brazil
- Year and Date
  2014-09-01
- Data Source
  KAKENHI-PROJECT-23390038
[Presentation] 酸化ストレス下におけるポリアミンモジュロンの生理的役割解明2014
- Author(s)
  山本拓, 吉田健人, 照井祐介, 坂本明彦, 山本兼由, 石浜明, 鈴木秀之, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第5回年会
- Place of Presentation
  銚子・千葉科学大学
- Year and Date
  2014-01-23
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] アクロレイン耐性細胞Neuro2a-ATD-2の毒性解除機構の解明2014
- Author(s)
  中村瑞穂, 坂本明彦, 照井祐介, 富取秀行, 斎木遼太郎, 吉田円, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第5回年会
- Place of Presentation
  銚子・千葉科学大学
- Year and Date
  2014-01-23
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle.2013
- Author(s)
  Kashiwagi, K. et al.
- Organizer
  2013 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23390038
[Presentation] Identification of proteins including acrolein in saliva of primary Sjögren syndrome patients.2013
- Author(s)
  Saiki, R., Hirose, T., Suzuki, T., Dohmae, N, Ito, S., Toida, T., Kashiwagi, K., Igarashi, K.
- Organizer
  2013 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] GAPDHを介したアクロレイン毒性機序の解明2013
- Author(s)
  中村瑞穂, 富取秀行, 鈴木健裕, 照井祐介, 斎木遼太郎, 堂前直, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第4回大会
- Place of Presentation
  松島・ホテル大観荘
- Year and Date
  2013-01-25
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle.2013
- Author(s)
  Kashiwagi, K., Yamashita, T., Nishimura, K., Saiki, R., Okudaira, H., Tome, M., Higashi, K., Nakamura, M., Terui, Y., Fujiwara, K., Igarashi, K.
- Organizer
  2013 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Enhanced cell viability by polyamines under oxidative stress through polyamine stimulation of SoxR and EmrR in Escherichia coli.2013
- Author(s)
  Terui, Y., Sakamoto, A., Tamada, A., Ichihara, T., Yamamoto, T., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.
- Organizer
  2013 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle2013
- Author(s)
  Kashiwagi, K., Yamashita, T., Nishimura, K., Saiki, R., Okudaira, H., Tome, M., Higashi, K., Nakamura, M., Terui, Y., Fujiwara, K., Igarashi, K
- Organizer
  2013 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 大腸菌プトレスシン輸送蛋白質PotFGHI及びPuuPの生理的意義の解明2013
- Author(s)
  照井祐介, Sunil D. Saroj, 坂本明彦, 吉田健人, 東恭平, 斎木遼太郎, 栗原新, 鈴木秀之, 戸井田敏彦, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 大腸菌及び動物細胞におけるポリアミンによる翻訳の効率化機構2013
- Author(s)
  柏木敬子,五十嵐一衛
- Organizer
  シンポジウム「神秘の生理活性物質ポリアミン研究の新展開」日本農芸化学会2013仙台大会
- Place of Presentation
  東北大学川内キャンパス
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Comprehensive analysis of glycosaminoglycans in mammalian cells cultured in the presence or absence of polyamines: identification of polyamine modulon in glycosaminoglycan synthesis.2013
- Author(s)
  Higashi, K., Imamura, M., Furihata, T., Nishimura, K., Linhardt, R. J., Kashiwagi, K., Igarashi, K., Toida, T.
- Organizer
  2013 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 酸化ストレス下における大腸菌のポリアミンの生存率維持の役割2013
- Author(s)
  照井祐介, 坂本明彦, 玉田朗人, 市原朋昌, 山本拓, 山本兼由, 石浜明,五十嵐一衛, 柏木敬子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Polyamine stimulation of eEF1A synthesis based on the unusual position of an SD-like sequence of eEF1A mRNA.2013
- Author(s)
  Sakamoto, A., Terui, Y., Kasahara, T., Yoshida, T., Tomitori, H., Igarashi, K., Kashiwagi, K.
- Organizer
  2013 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil2012
- Author(s)
  Kashiwagi, K., Tomitori, H., Suganami, A., Saiki, R., Mizuno, S., Yoshizawa, Y., Masuko, T., Tamura, Y., Nishimura, K., Toida, T., Williams, K., Igarashi, K
- Organizer
  International Congress on"Polyamines : Biological and Clinical Perspectives"
- Place of Presentation
  Istanbul, Turkey, Istanbul Kültür University
- Year and Date
  2012-09-03
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Identification and its effect on cell growth of acrolein-conjugated protein in mouse mammary carcinoma FM3A cells.2012
- Author(s)
  Tomitori, H., Nakamura, M., Suzuki, T., Terui, Y., Yoshida, M., Saiki, R., Dohmae, N., Igarashi, K., Kashiwagi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul Kultur University, Turkey
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミンによる大腸菌二成分制御系蛋白質UvrY及びCpxR合成促進に基づくバイオフィルム形成上昇2012
- Author(s)
  坂本明彦, 照井祐介, 山本拓, 笠原拓馬, 富取秀行, 山本兼由, 石浜明, 五十嵐一衛, 柏木敬子
- Organizer
  日本薬学会第132年会
- Place of Presentation
  日北海道大学高等教育推進機構
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] マウス神経芽細胞腫及びマウス乳がん細胞におけるアクロレイン毒性の解毒機構2012
- Author(s)
  富取秀行, 中村瑞穂, 坂本明彦, 照井祐介, 吉田円, 柏木敬子, 五十嵐一衛
- Organizer
  日本ポリアミン学会第3回年会
- Place of Presentation
  さいたま市民会館おおみや小ホール
- Year and Date
  2012-01-26
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミンによるバイオフィルム形成能及び生存率の上昇2012
- Author(s)
  坂本明彦, 照井祐介, 山本拓, 笠原拓馬, 富取秀行, 山本兼由, 石浜明, 五十嵐一衛, 柏木敬子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Enhanced biofilm formation and cell viability by polyamines through polyamine stimulation of response regulators UvrY and CpxR in the two-component signal transducing systems and ribosome recycling factor.2012
- Author(s)
  Sakamoto, A., Terui, Y., Yamamoto, T., Kasahara, T., Tomitori, H., Yamamoto, K., Ishihama, A., Michael, A. J., Igarashi, K., Kashiwagi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul Kultur University, Turkey
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 脳梗塞患者における尿中アクロレイン―グルタチオン代謝物3-HPMA（3-ヒドロキシプロピルメルカプツール酸）の低下.2012
- Author(s)
  柏木敬子
- Organizer
  日本ポリアミン学会第3回年会
- Place of Presentation
  さいたま市民会館おおみや
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Comparison of putrescine uptake catalyzed by PotFGHI and PuuP in Escherichia coli.2012
- Author(s)
  Terui, Y., Saroj, S. D., Sakamoto, A., Yoshida, T., Higashi, K., Saiki, R., Kurihara, S., Suzuki, H., Toida, T., Kashiwagi, K., Igarashi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul Kultur University, Turkey
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Properties of polyamine uptake by human organic cation transporter 2.2012
- Author(s)
  Higashi, K., Uemura, T., Toida, T., Kashiwagi, K. Igarashi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul Kultur University, Turkey
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Structure and functions of R domains of NMDA receptors NR1 and NR2B2011
- Author(s)
  Kashiwagi, K., Mizuno, S., Tomitori, H., Yoshizawa, Y., Han, X., Higashi, K., Saiki, R., Nishimura, K., Toida, T., Williams, K., Igarashi, K
- Organizer
  2011 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA, Waterville Valley Resort
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] NMDA受容体調節領域NRIRとNR2BRの構造と機能2011
- Author(s)
  吉沢祐樹, 水野聡美, 富取秀行, 韓霞, 益子崇, 菅波晃子, 田村裕, 東恭平, 斎木遼太郎, 西村和洋, 戸井田敏彦, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] 原核細胞と真核細胞のポリアミンモジュロン:ポリアミンによる遺伝子発現制御の包括的理解2011
- Author(s)
  柏木敬子, 五十嵐一衛
- Organizer
  第84回日本生化学会大会シンポジウム「いろいろな生物に見られるポリアミンの多様な機能と代謝」シンポジスト
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミンによるppGppの合成促進及びRpoZ-ppGpp複合体を介したRNA合成調節による大腸菌の生存率上昇.2011
- Author(s)
  坂本明彦, 照井祐介, 秋山真律子, 富取秀行, 山本兼由, 石浜明, 五十嵐一衛, 柏木敬子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Structure and functions of R domains of NMDA receptors NR1 and NR2B.2011
- Author(s)
  Kashiwagi, K.
- Organizer
  2011 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 原核細胞と真核細胞のポリアミンモジュロン:ポリアミンによる遺伝子発現制御の包括的理解2011
- Author(s)
  柏木敬子, 五十嵐一衛
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23390038
[Presentation] Structure and functions of R domains of NMDA receptors NR1 and NR2B2011
- Author(s)
  Kashiwagi, K., et al
- Organizer
  2011 Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Data Source
  KAKENHI-PROJECT-23390038
[Presentation] スペルミジン輸送活性に関与するPotB及びPotCのアミノ酸残基の同定とその機能2011
- Author(s)
  柏木敬子, 酒巻善春, 東恭平, 戸来江美子, 出水理砂, 植村武, Sunil D. Saroj, 照井祐介, 西村和洋, 戸井田敏彦, 五十嵐一衛
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] メタボリックシンドロームと血漿蛋白質抱合アクロレイン、IL-6、CRPより求めた脳梗塞リスク値との相関2011
- Author(s)
  柏木敬子
- Organizer
  日本ポリアミン学会第2回年会
- Place of Presentation
  帝京大学宇都宮キャンパス
- Year and Date
  2011-01-27
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] 原核細胞と真核細胞のポリアミンモジュロン：ポリアミンによる遺伝子発現制御の包括的理解.2011
- Author(s)
  柏木敬子
- Organizer
  第84回日本生化学会大会(招待講演)
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 無症候性脳梗塞,頸部動脈硬化及び大脳白質病変の画像とアクロレイン,IL・6及びCRPの血漿レベルとの相関2010
- Author(s)
  柏木敬子, 吉田円, 東恭平, 小林英一, 佐伯直勝, 町佳樹, 溝井睦美, 戸井田敏彦, 神崎哲人, 富取秀行, 五十嵐一衛
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Correlation between images of silent brain infarction, carotid atherosclerosis and white matter hyperintensity, and plasma levels of acrolein, IL-6 and CRP.2010
- Author(s)
  Kashiwagi, K.
- Organizer
  2010 International Polyamine Conference
- Place of Presentation
  御殿場高原ホテルBU
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Identification and functions of amino acid residues in PotB and PotC involved in spermidine uptake activity.2010
- Author(s)
  Higashi K., Sakamaki Y., Herai E., Demizu R., Uemura T., Saroj S. D., Zenda R., Terui Y., Nishimura K., Toida T., Kashiwagi K., Igarashi K.
- Organizer
  2nd International Conference on the Role of Polyamines and their Analogs in Cancer and other Diseases
- Place of Presentation
  Rome, Italy
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] 無症候性脳梗塞,頸部動脈硬化及び大脳白質病変の画像とアクロレイン,IL-6及びCRPの血漿レベルとの相関2010
- Author(s)
  柏木敬子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Polyamine modulon in Escherichia coli, yeast and mammalian cells.2010
- Author(s)
  Kashiwagi, K.
- Organizer
  2nd International Conference on the Role of Polyamines and their Analogs in Cancer and other Diseases
- Place of Presentation
  Rome, Italy
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] ポリアミンから産生されるアクロレインの脳梗塞巣形成に果たす役割2010
- Author(s)
  斎木遼太郎, 朴恵林, 石井伊都子, 西村和洋, 戸井田敏彦, 辰川英樹, 小嶋聡一, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第130年会
- Place of Presentation
  就実大学,岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Polyamine modulation in Escherichia coli, yeast and mammalian cells.2010
- Author(s)
  Kashiwagi K., Terui Y., Uemura T., Higashi K., Okudaira H., Ochiai E., Akiyama M., Tomitori H., Nishimura K., Toida T., Igarashi K.
- Organizer
  2nd International Conference on the Role of Polyamines and their Analogs in Cancer and other Diseases
- Place of Presentation
  Rome, Italy
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Correlation between images of silent brain infarction, carotid atherosclerosis and white matter hyperintensity, and plasma levels of acrolein, IL-6 and CRP.2010
- Author(s)
  Kashiwagi K., Yoshida M., Higashi K., Kobayashi E., Saeki N., Machi Y., Mizoi M., Toida T., Kanzaki T., Tomitori, H. Igarashi K.
- Organizer
  2010 International Polyamine Conference, Gotemba, Japan
- Place of Presentation
  御殿場高原ホテルBU
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] 脳梗塞のアクロレイン産生におけるトランスグルタミナーゼ2の役割.2009
- Author(s)
  斎木遼太郎、東恭平、石井伊都子、西村和洋、戸井田敏彦、辰川英樹、小嶋聡一、柏木敬子、五十嵐一衛
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] スペルミン及びイフェンプロジルのNMDA受容体調節領域への結合能2009
- Author(s)
  韓霞, 富取秀行, 水野聡美, 東恭平, 吹言睾友秀, 照井祐介, 西村和洋, 戸井田敏彦, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Intense correlation between brain infarction and protein-conjugated acrolein.2009
- Author(s)
  Saiki, R., Nishimura, K., Ishii, I., Omura, T., Okuyama, S., Kashiwagi, K., Igarashi, K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Polyamine effect on protein synthesis and its mechanism.2009
- Author(s)
  Kashiwagi, K., Terui, Y., Higashi, K., Okudaira, H., Ochiai, E., Tomitori, H., Nishimura, K., Yamamoto, K., Ishihama, A., Igarashi, K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] スペルミン及びイフェンプロジルのNMDA受容体調節領域への結合能2009
- Author(s)
  韓霞, 富取秀行, 水野聡美, 東恭平, 吹譯友秀, 照井祐介, 西村和洋, 戸井田敏彦, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] マウス神経芽細胞腫Neuro2aにおけるアクロレイン耐性機構の探索.2009
- Author(s)
  坂本明彦、富取秀行、中村瑞穂、照井祐介、吉田円、柏木敬子、五十嵐一衛
- Organizer
  東京慈恵会医科大学学外共同研究シンポジウムポリアミンと核酸の共進化第8回合同シンポジウム
- Place of Presentation
  東京慈恵会医科大学
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] アクロレイン耐性細胞の樹立とそのアクロレイン毒性除去機構.2009
- Author(s)
  中村瑞穂、富取秀行、照井祐介、吉田円、柏木敬子、五十嵐一衛
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] ポリアミン酸化により産生されるアクロレインの毒性 : 活性酸素種との比較2009
- Author(s)
  富取秀行, 吉田円, 町佳樹, 萩原基文, 東恭平, 合田ひとみ, 大谷武司, 新津勝, 柏木敬子, 五十嵐一衛
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 細胞周期進行におけるポリアミンの役割解析2009
- Author(s)
  柏木敬子, 山下智子, 西村和洋, 奥平宏之, 當銘真悠子, 東恭平, 藤原邦雄, 五十嵐一衛
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Binding of spermine and ifenprodil to a regulatory domain (R-domain) of the N-methyl-Daspartate (NMDA) receptor and the role of R-domain on the activity of NMDA receptor.2009
- Author(s)
  Kashiwagi K., Han X., Mizuno S., Tomitori H., Higashi K., Terui Y., Nishimura K., Toida T., Williams K., Igarashi K.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Polyamine effect on protein synthesis and its mechanism2009
- Author(s)
  Kashiwagi, K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] アクロレイン耐性細胞の樹立とそのアクロレイン毒性除去機構2009
- Author(s)
  中村瑞穂, 富取秀行, 照井祐介, 吉田円, 柏木敬子, 五十嵐一衛
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] ポリアミン酸化により産生されるアクロレインの毒性:活性酸素種との比較.2009
- Author(s)
  富取秀行、吉田円、町佳樹、萩原基文、東恭平、合田ひとみ、大谷武司、新津勝、柏木敬子、五十嵐一衛
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Polyamine effect on protein synthesis and its mechanism.2009
- Author(s)
  Kashiwagi K., Terui Y., Higashi K., Okudaira H., Ochiai E., Tomitori H., Nishimura K., Yamamoto K., Ishihama A., Igarashi K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Binding of spermine and ifenprodil to a regulatory domain (R-domain) of the N-methyl-D-aspartate (NMDA) receptor and the role of R-domain on the activity of NMDA receptor.2009
- Author(s)
  Kashiwagi, K., Han, X., Mizuno, S., Tomitori, H., Higashi, K., Terui, Y., Nishimura, K., Toida, T., Williams, K., Igarashi, K.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Polyamine stimulation of the synthesis of RpoE and StpA at the level of translatiohn in Escherichia coli under heat shock conditions.2009
- Author(s)
  Terui, Y., Tabei, Y., Higashi, K., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.
- Organizer
  Biogenic Amines : Biochemical, Physiological, and Clinical Aspects
- Place of Presentation
  Bertinoro, Italy
- Year and Date
  2009-05-14
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Isolation and characterization of an acrolein tolerant mutant of FM3A cells.2009
- Author(s)
  Tomitori, H., Nakamura, M., Yoshida, M., Kashiwagi, K., Igarashi, K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Binding of spermine and ifenprodil to a regulatory domain(R-domain)of the N-methyl-D-aspartate(NMDA)receptor and the role of R-domain on the activity of NMDA receptor2009
- Author(s)
  Kashiwagi, K.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] 細胞周期進行におけるポリアミンの役割解析2009
- Author(s)
  柏木敬子, 山下智子, 西村和洋, 奥平宏之, 當銘真悠子, 東恭平, 藤原邦雄, 五十嵐一衛
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] ポリアミンか産生されるアクロレインの脳梗塞形成に及ぼす効果.2009
- Author(s)
  斎木遼太郎、東恭平、石井伊都子、西村和洋、戸井田敏彦、池口文彦、A.E.Pegg、柏木敬子、五十嵐一衛
- Organizer
  東京慈恵会医科大学学外共同研究シンポジウムポリアミンと核酸の共進化第8回合同シンポジウム
- Place of Presentation
  東京慈恵会医科大学
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Binding of spermine and ifenprodil to a regulatory domain (R-domain) of the N-methyl-D-aspartate (NMDA) receptor and the role of R-domain on the activity of NMDA receptor2009
- Author(s)
  Kashiwagi, K., Han, X., Mizuno, S., Tomitori, H., Higashi, K., Terui, Y., Nishimura, K., Toida, T., Williams, K., Igarashi, K.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター場
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 脳梗塞時のアクロレイン産生におけるトランスグルタミナーゼ2の役割2009
- Author(s)
  斎木遼太郎, 東恭平, 石井伊都子, 西村和洋, 戸井田敏彦, 辰川英樹, 小嶋聡一, 柏木敬子, 五十嵐一衛
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Identification and function of amino acid residues on PotB and PotC involved in spermidine uptake activity.2009
- Author(s)
  Higashi, K., Sakamaki, Y., Uemura, T., Herai, E., Demizu, R., Zenda, R., Toida, T., Kashiwagi, K., Igarashi, K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Polyamine effect on protein synthesis and its mechanism2009
- Author(s)
  Kashiwagi, K., Terui, Y., Higashi, K., Okudaira, H., Ochiai, E., Tomitori, H., Nishimura, K., Yamamoto, K., Ishihama, A., Igarashi, K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 大腸菌 OppA mRNA及びラット肝Ile-tRNAにおける二重鎖RNAのバルジ構造のスペルミンによる選択的な構造変化2008
- Author(s)
  東恭平, 菅波晃子, 田村裕, 照井裕介, 西村和洋, 柏木敬子, 五十嵐一衛
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 大腸菌スペルミジン優先取り込み系の膜貫通蛋白質PotB及びPotCの性質2008
- Author(s)
  出水梨沙, 東恭平, 酒巻善春, 植村武史, 戸来江美子, 善田理沙, 西村和洋, 柏木敬子, 五十嵐一衛
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Polyamine modulon in Escherichia coli and eukaryotic cells.2008
- Author(s)
  Kashiwagi, K., et al.
- Organizer
  Polyamines : Forty years of mammalian ornithine decarboxylase
- Place of Presentation
  Kuopio, Finland
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] 定常期におけるポリアミンの大腸菌の生存率維持に果たす役割2008
- Author(s)
  照井裕介,東恭平,田部井譲,秋山真律子,富取秀行,山本兼由,石浜明,五十嵐一衛,柏木敬子
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 大腸菌スペルミジン優先取り込み系の膜貫通蛋白質 PotB及び PotCの性質2008
- Author(s)
  出水梨沙, 東恭平, 酒巻善春, 植村武史, 戸来江美子, 善田理沙, 西村和洋, 柏木敬子, 五十嵐一衛
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 大腸菌OppAmRNA及びラット肝lle-tRNAにおける二重鎖RNAのバルジ構造のスペルミンによる選択的な構造変化2008
- Author(s)
  東恭平,菅波晃子,田村裕,照井裕介,西村和彦,柏木敬子,五十嵐一衛
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] NMDA受容体の膜領域の構造の解析2008
- Author(s)
  金麗花, 田村真紀, 瀧川美紀, 廣瀬直雄, 西村和洋, 戸井田敏彦, K. Williams, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Polyamine modulon in Escherichia coli and cukaryotic cells.2008
- Author(s)
  Kashiwagi, K. et al.
- Organizer
  Polyamines: Forty years of mammalian ornithine decarboxylase
- Place of Presentation
  Kuopio, Finland
- Year and Date
  2008-07-28
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 大腸菌スペルミジン優先取り込み系の膜貫通蛋白質PodB及びPotCの性質2008
- Author(s)
  出水梨沙,東恭平,酒巻善春,植村武史,戸来江美子,善田理沙,西村和彦,柏木敬子,五十嵐一衛,木敬子,五十嵐一衛
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] スペルミンによるNMDA受容体活性促進効果とチャネルブロック作用に影響するチャネル領域の同定2008
- Author(s)
  柏木敬子, 金麗花, 宮崎真紀, 水野聡美, 瀧川美紀, 廣瀬直雄, 西村和洋, 戸井田敏彦, K. Williams, 五十嵐一衛
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2008-08-08
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] スペルミンによるNMDA受容体活性促進効果とチャネルブロック作用に影響するチャネル領域の同定2008
- Author(s)
  柏木敬子, 金麗花, 宮崎真紀, 水野聡美, 瀧川美紀, 廣瀬直雄, 西村和洋, 戸井田敏彦, K. Williams, 五十嵐一衛
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2008-08-08
- Data Source
  KAKENHI-PROJECT-20590066
[Presentation] Acrolein toxicity : its mechanism and comparison of toxicity with reactive oxygen species2007
- Author(s)
  Yoshida, M., Hagihara, M., Tomitori, H., Nishimura, K., Kashiwagi, K., Igarashi, K.
- Organizer
  International Congress on Biogenic Amines : Biological and Clinical Perspectives
- Place of Presentation
  Sicily, Italy
- Year and Date
  2007-10-17
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-D-aspartate receptor2007
- Author(s)
  Kashiwagi, K., et. al.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590069
[Presentation] Binding of spermine and ifenprodil to a Purified,soluble regulatory domain of the N-methyl-D-aspartate receptor.2007
- Author(s)
  Kashiwagi, K., et. al.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley,NH,USA
- Year and Date
  2007-06-17
- Data Source
  KAKENHI-PROJECT-18590069
[Presentation] 動物細胞のポリアミンにより翻訳レベルで合成促進を受ける蛋白質の同定2007
- Author(s)
  落合絵里子, 奥平宏之, 西村和洋, 柏木敬子, 堂前直, 西村友枝, 瀧尾擴士, 五十嵐一衛
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Binding of spermine and ifenprodil to a purified,soluble regulatory domain of the N-methyl-D-aspartate receptor2007
- Author(s)
  Kashiwagi, K., et. al.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley,NH,USA
- Year and Date
  2007-06-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590069
[Presentation] 大腸菌及び動物細胞におけるポリアミンによる翻訳の効率化機構
- Author(s)
  柏木敬子，五十嵐一衛
- Organizer
  日本農芸化学会2013仙台大会シンポジウム「神秘の生理活性物質ポリアミン研究の新展開」
- Place of Presentation
  東北大学川内キャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミン過剰蓄積による細胞増殖阻害機構の解明
- Author(s)
  坂本明彦, 照井祐介, 吉田健人, 山本兼由, 石浜　明, 五十嵐一衛, 柏木敬子
- Organizer
  「ポリアミンと核酸の共進化」第12回合同シンポジウム
- Place of Presentation
  東京慈恵会医科大学
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミンによる翻訳伸長因子eIF1Aの蛋白質合成促進機構の解明
- Author(s)
  坂本明彦, 照井祐介, 吉田健人, 笠原拓馬, 富取秀行, 五十嵐一衛, 柏木敬子
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] シェーグレン症候群患者唾液中におけるアクロレイン化タンパク質の機能解析
- Author(s)
  斎木遼太郎, 廣瀬直雄, 鈴木健裕, 益田晶子, 堂前　直, 伊藤　聡, 高橋芳右, 戸井田敏彦, 柏木敬子, 五十嵐一衛
- Organizer
  日本ポリアミン学会第5回年会
- Place of Presentation
  銚子・千葉科学大学マリーナキャンパス
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] ポリアミンによるバイオフィルム形成能及び生存率の上昇
- Author(s)
  坂本明彦, 照井祐介, 山本　拓, 笠原拓馬, 富取秀行, 山本兼由, 石浜　明, 五十嵐一衛, 柏木敬子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 細胞周期進行におけるポリアミンの機能解析
- Author(s)
  山下智子, 西村和洋, 斎木遼太郎, 奥平宏之, 當銘真悠子, 東　恭平, 照井祐介, 藤原邦雄, 柏木敬子, 五十嵐一衛
- Organizer
  日本ポリアミン学会第4回大会
- Place of Presentation
  松島・ホテル大観荘
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 翻訳因子eIF1Aのポリアミンによる蛋白質合成促進機構の解明
- Author(s)
  笠原拓馬, 照井祐介, 吉田健人, 坂本明彦, 富取秀行, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第4回大会
- Place of Presentation
  松島・ホテル大観荘
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] マウス神経芽細胞腫Neuro2a由来の新規アクロレイン耐性細胞の性質
- Author(s)
  中村瑞穂, 坂本明彦, 照井祐介, 富取秀行, 斎木遼太郎, 吉田　円, 五十嵐一衛, 柏木敬子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] サメ肌抗菌シートによる緑膿菌のバイオフィルム形成及びswarming motilityの抑制
- Author(s)
  坂本明彦, 照井祐介, 堀江千紘, 福井貴史, 増澤俊幸, 菅原申太郎, 重田　核, 重田龍男, 五十嵐一衛, 柏木敬子
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本・熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] スペルミンおよびイフェンプロジルの結合によるNMDA受容体GluN1及びGluN2BのN末端調節領域の構造変化
- Author(s)
  斎木遼太郎, 富取秀行, 菅波晃子, 水野聡美, 吉沢祐基, 益子　崇, 田村　裕, 西村和洋, 戸井田敏彦, キースウィリアムス, 柏木敬子, 五十嵐一衛
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] アクロレイン耐性細胞Neuro2a-ATD-2の毒性解除機構の解明
- Author(s)
  中村瑞穂, 坂本明彦, 照井祐介, 富取秀行, 斎木遼太郎, 吉田　円, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第5回年会
- Place of Presentation
  銚子・千葉科学大学マリーナキャンパス
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 軽度認知障害及びアルツハイマー病患者における血漿蛋白質抱合アクロレイン及びアミロイドβ40/42比の上昇
- Author(s)
  吉田　円, 藁谷正明, 溝井睦美, 斎木遼太郎, 植村研一, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] シェーグレン症候群患者唾液中におけるアクロレイン結合タンパク質の機能解析
- Author(s)
  廣瀬直雄, 斎木遼太郎, 鈴木健裕, 益田晶子, 堂前　直, 伊藤　聡, 高橋芳右, 戸井田敏彦, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本・熊本大学
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] GAPDHを介したアクロレイン毒性機序の解明
- Author(s)
  中村瑞穂, 富取秀行, 鈴木健裕, 照井祐介, 斎木遼太郎, 堂前　直, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第4回大会
- Place of Presentation
  松島・ホテル大観荘
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil.
- Author(s)
  Kashiwagi, K., Tomitori, H., Suganami, A., Saiki, R., Mizuno, S., Yoshizawa, Y., Masuko, T., Tamura, Y., Nishimura, K., Toida, T., Williams, K., Igarashi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul Kultur University, Turkey
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 大腸菌プトレスシン輸送蛋白質PotFGHI及びPuuPの生理的意義の解明
- Author(s)
  照井祐介, Sunil D. Saroj, 坂本明彦, 吉田健人, 東　恭平, 斎木遼太郎, 栗原　新, 鈴木秀之, 戸井田敏彦, 柏木敬子, 五十嵐一衛
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil.
- Author(s)
  Kashiwagi, K.
- Organizer
  International Congress on “Polyamines: Biological and Clinical Perspectives”
- Place of Presentation
  Istanbul, Turky
- Data Source
  KAKENHI-PROJECT-23390038
[Presentation] シェーグレン症候群患者唾液中のアクロレイン結合タンパク質の同定
- Author(s)
  斎木遼太郎, 廣瀬直雄, 鈴木健裕, 益田晶子, 堂前　直, 伊藤　聡, 高橋芳右, 戸井田敏彦, 柏木敬子, 五十嵐一衛
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 酸化ストレス下におけるポリアミンの細胞増殖並びに細胞生存率に果たす役割
- Author(s)
  吉田健人, 坂本明彦, 照井祐介, 山本　拓, 山本兼由, 石浜　明, 鈴木秀之, 五十嵐一衛, 柏木敬子
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本・熊本大学
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 酸化ストレス下におけるポリアミンモジュロンの生理的役割解明
- Author(s)
  山本　拓, 吉田健人, 照井祐介, 坂本明彦, 山本兼由, 石浜　明, 鈴木秀之, 五十嵐一衛, 柏木敬子
- Organizer
  日本ポリアミン学会第5回年会
- Place of Presentation
  銚子・千葉科学大学マリーナキャンパス
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 酸化ストレス下における大腸菌のポリアミンの生存率維持の役割
- Author(s)
  照井祐介, 坂本明彦, 玉田朗人, 市原朋昌, 山本　拓, 山本兼由, 石浜　明, 五十嵐一衛, 柏木敬子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] アクロレイン抱合GAPDHを介したアクロレインの細胞毒性機序
- Author(s)
  中村瑞穂, 富取秀行, 鈴木健裕, 照井祐介, 斎木遼太郎, 堂前　直, 五十嵐一衛, 柏木敬子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590088
[Presentation] 真核細胞における新規ポリアミンモジュロンの同定及び蛋白質合成促進機構の解明
- Author(s)
  吉田健人, 照井祐介, 笠原拓馬, 坂本明彦, 永池　誠, 富取秀行, 五十嵐一衛, 柏木敬子
- Organizer
  「ポリアミンと核酸の共進化」第11回合同シンポジウム
- Place of Presentation
  東京慈恵会医科大学西新橋校西講堂
- Data Source
  KAKENHI-PROJECT-23590088

1. IGARASHI Kazuei (60089597)

# of Collaborated Projects: 19 results

# of Collaborated Products: 53 results
2. KAKINUMA Yoshimi (80134394)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. SHIRAHATA Akira (50150107)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. NISHIMURA Kazuhiro (60302569)

# of Collaborated Projects: 4 results

# of Collaborated Products: 29 results
5. KOBAYASHI Hiroshi (00090473)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. WILLIAMS Keith

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KEITH Willia

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TOMITORI Hideyuki (30337381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 42 results
9. TERUI Yusuke (60433687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 47 results
10. 植村武史 (50401005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. STEFANIA Biondi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NELLO Bagni

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOIDA Toshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
14. AKATSU Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. WARAGAI Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. SUZUKI Toyofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. TAMURA Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. SUGANAMI Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. YAMANAKA Masamichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 東恭平

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
21. 松村浩由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 井上豪

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 鈴木秀之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kashiwagi keiko 柏木 敬子

KASHIWAGI Keiko 柏木 敬子

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Physiological role of polyamines and regulation of their cellular contentsPrincipal Investigator

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Structure and functions of polyamine transport proteins and NMDA receptorsPrincipal Investigator

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Molecular mechanism and physiological role of polyamine transport systems and NMDA receptorsPrincipal Investigator

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Structure and function of polyamine transport systems and NMDA receptorsPrincipal Investigator

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聴覚障害を惹起しないアミノグリコシド系抗菌薬とVNC細菌に作用する抗菌薬の開発Principal Investigator

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Characterization of polyamine transport systems and modulation of NMDA receptor by polyaminesPrincipal Investigator

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ポリアミン輸送系とNMDA受容体の構造・機能協関Principal Investigator

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kashiwagi keiko 柏木敬子

KASHIWAGI Keiko 柏木敬子