Kojima Naoshi 小島直

… Alternative Names

KOJIMA Naoshi 小島直

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Researcher Number	30356985
Other IDs
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help	2017 – 2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2015 – 2016: 国立研究開発法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 2008 – 2009: National Institute of Advanced Industrial Science and Technology, ゲノムファクトリー研究部門, 主任研究員 2007: National Institute of Advanced Industrial Science and Technology, ゲノムファクトリー研究部門, 主任研究員 2004 – 2006: National Institute of Advanced Industrial Science and Technology, Research Institute of Genome-based Biofactory, Research Scientist, ゲノムファクトリー研究部門, 研究員 2003: 独立行政法人産業技術総合研究所, 生物機能工学研究部門, 研究員
Review Section/Research Field	Principal Investigator Living organism molecular science / Basic Section 34020:Analytical chemistry-related / Chemical pharmacy Except Principal Investigator Basic Section 28050:Nano/micro-systems-related / Analytical chemistry / Biomolecular chemistry / Living organism molecular science
Keywords	Principal Investigator 核酸プローブ / ルシフェリン / 生物発光 / 遺伝子検出 / 検出 / 合成化学 / 分子認識 / 遺伝子 / 核酸 / 凝集誘起発光 … More / 核酸化学 / 親水性相互作用 / 疎水性相互作用 / 低分子リガンド / 損傷塩基 / ミスマッチ塩基対 / 塩基対 / 機能性核酸 / 機能生核酸 / 合成後修飾 / オリゴヌクレオチド / ポリメラーゼ / 核酸合成酵素 / 1-デアザグアノシン / デアザヌクレオシド / 核酸誘導体 … More Except Principal Investigator RNA / siRNA / OPN / がん / 電極 / マーカー分子検出 / ナノ粒子 / 微粒子 / 微小電極 / がん細胞 / 電気化学発光 / 分析科学 / メチルシトシン / バイオセンサ / µTAS / 一細胞 / 一分子 / メチル化DNA / マイクロデバイス / エピジェネティクス / ゴカイ / 発光生物 / 発光ゴカイ / ルシフェラーゼ / ルシフェリン / 生物発光 / oligonucleotide / hepatitis / concanavarin A / metastasis / Osteopontin / リン酸化糖タンパク質 / 炎症疾患 / RNAi / 癌転移 / Concanavalin A / オリゴヌクレオチド / 肝炎 / concanavalin A / 転移 / オステオポンチン Less

Use of bioluminescence to improve the sensitivity of gene detection technologyPrincipal Investigator
- Principal Investigator
  
  小島直
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Detection of target molecules expressed on a cell surface based on electrochemiluminescence
- Principal Investigator
  
  Kim Hyonchol
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28050:Nano/micro-systems-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Epigenome analysis on an array device for single cell / genome
- Principal Investigator
  
  KURITA RYOJI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Analytical chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Novel molecular mechanisms of luminous fireworm
- Principal Investigator
  
  Mitani Yasuo
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Building up the bioluminescence molecule on the nucleic acid sequence and its application to gene detection technologyPrincipal Investigator
- Principal Investigator
  
  KOJIMA Naoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Synthesis of novel chemical ligand that selectively bind to the unstabilized base pairs formed in DNAPrincipal Investigator
- Principal Investigator
  
  KOJIMA Naoshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
分子間相互作用を利用したRNA末端部位標識化試薬の開発Principal Investigator
- Principal Investigator
  
  小島直
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
非天然型ヌクレオシドの合成と、これを利用した核酸合成酵素認識機構の解析Principal Investigator
- Principal Investigator
  
  小島直
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Investigation of regulatory mechanism of homeostasis using functional nucleic acids.
- Principal Investigator
  
  KOMATSU Yasuo, 大塚榮子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2009 2008 2006 2005 2003

All Journal Article Presentation Patent

[Journal Article] Development of gapmer antisense oligonucleotide with deoxyribonucleic guanidine (DNG) modifications2019
- Author(s)
  Kojima Naoshi、Shrestha Ajaya R.、Akisawa Takuya、Piao Haishun、Kizawa Hideki、Ohmiya Yoshihiro、Kurita Ryoji
- Journal Title
  
  Nucleosides, Nucleotides & Nucleic Acids
  
  Volume: 39 Issue: 1-3 Pages: 258-269
- DOI
  10.1080/15257770.2019.1668563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03084
[Journal Article] Immobilization of DNA on Biosensing Devices with Nitrogen Mustard Modified Linkers2019
- Author(s)
  栗之丸隆章、小島直、栗田僚二
- Journal Title
  
  Current Protocols in Nucleic Acid Chemistry
  
  Volume: 77 Issue: 1
- DOI
  10.1002/cpnc.85
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06192, KAKENHI-PROJECT-17H03084, KAKENHI-PROJECT-18K14258
[Journal Article] Sequential Assessment of Multiple Epigenetic Modifications of Cytosine in Whole Genomic DNA by Surface Plasmon Resonance2019
- Author(s)
  栗之丸隆章、小島直、栗田僚二
- Journal Title
  
  Analytical Chemistry
  
  Volume: 91 Issue: 21 Pages: 13933-13939
- DOI
  10.1021/acs.analchem.9b03423
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06192, KAKENHI-PROJECT-17H03084, KAKENHI-PROJECT-18K14258
[Journal Article] Immobilization of DNA with nitrogen mustard-biotin conjugate for global epigenetic analysis2018
- Author(s)
  小島直、須田友美、栗之丸隆章、栗田僚二
- Journal Title
  
  Analytica Chimica Acta
  
  Volume: 1043 Pages: 107-114
- DOI
  10.1016/j.aca.2018.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06192, KAKENHI-PROJECT-18K14258, KAKENHI-PROJECT-17H03084
[Journal Article] An alkylating immobilization linker for immunochemical epigenetic assessment2017
- Author(s)
  Kurinomaru Takaaki、Kojima Naoshi、Kurita Ryoji
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 59 Pages: 8308-8311
- DOI
  10.1039/c7cc02883k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03084, KAKENHI-PROJECT-15K14933
[Journal Article] Development of a 3’-amino linker with high conjugation activity and its application to covalently cross-link blunt ends of a duplex2016
- Author(s)
  Keiko Kowata, Naoshi Kojima, Yasuo Komatsu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 24 Issue: 9 Pages: 2108-2113
- DOI
  10.1016/j.bmc.2016.03.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14933, KAKENHI-PROJECT-25293030
[Journal Article] Development of novel chemical probes to detect abasic sites in DNA2009
- Author(s)
  Naoshi Kojima
- Journal Title
  
  Nucleic Acids Symposium Series 53
  
  Pages: 45-46
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Efficient synthesis of oligonucleotide conjugates on solid-support using an (aminoethoxycarbonyl)aminohexyl group for 5'-terminal modification2009
- Author(s)
  Naoshi Kojima
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters 19
  
  Pages: 2144-2147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Efficient synthesis of oligonucleotide conjugates on solid-support using an (aminoethoxycarbonyl)- aminohexyl group for 5'-terminal modification2009
- Author(s)
  Kojima, N., Takebayashi, T., Mikami, A., Ohtsuka, E., Komatsu, Y.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 19
  
  Pages: 2144-2147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Construction of highly reactive probes for abasic site detection by introduction of an aromatic and a guanidine residue into an aminooxy group2009
- Author(s)
  Kojima, N., Takebayashi, T., Mikami, A., Ohtsuka, E., Komatsu, Y.
- Journal Title
  
  J. Am. Chem. Soc. 131
  
  Pages: 13208-13209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Construction of highly reactive probes for abasic site detection by introduction of an aromatic and a guanidine residue into an aminooxy group2009
- Author(s)
  Naoshi Kojima
- Journal Title
  
  Journal of the American Chemical Society 131
  
  Pages: 13208-13209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Comparison of the chemical properties of a novel amino-linker with various amino modifications2008
- Author(s)
  Kojima, N., Takebayashi, T., Mikami, A., Sugino, M., Ohtsuka, E., Komatsu, Y.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 463-464
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Comparison of the chemical properties of a novel amino-linker with various aminomodifications2008
- Author(s)
  Kojima, N.
- Journal Title
  
  Nucleic Acids Symposium Series 52
  
  Pages: 463-464
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Construction of an aminooxy derivative for RNA and DNA labeling2008
- Author(s)
  Komatsu, Y., Kojima, N., Takebayashi, T., Mikami, A., Sugino, M., Ohtsuka, E.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 393-394
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Construction of an aminooxy derivative for RNA and DNA labeling2008
- Author(s)
  Kojima, N.
- Journal Title
  
  Nucleic Acids Symposium Series 52
  
  Pages: 393-394
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue2006
- Author(s)
  Kojima, N
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry Letters 16・19
  
  Pages: 5118-5121
- Data Source
  KAKENHI-PROJECT-18710199
[Journal Article] High throughput purification of amino-modified oligonucleotides and its application to novel detection system of gene expression.2005
- Author(s)
  Kojima, N
- Journal Title
  
  Nucleic Acids Symposium Series No.49
  
  Pages: 181-182
- Data Source
  KAKENHI-PROJECT-16710166
[Journal Article] Generation of an Abasic Site in an Oligonucleotide by Using Acid-Labile 1-Deaza-2'-deoxyguanosine and its Application to Postsynthetic Modification2005
- Author(s)
  Kojima, N
- Journal Title
  
  Organic Letters 7・4
  
  Pages: 709-712
- Data Source
  KAKENHI-PROJECT-16710166
[Journal Article] Generation of an abasic site in an oligonucleotide by using acid-labile 1-deaza-2'-deoxyguanosine and its application to postsynthetic modification.2005
- Author(s)
  Kojima, N
- Journal Title
  
  Organic Letters 7・4
  
  Pages: 709-712
- Data Source
  KAKENHI-PROJECT-15310157
[Journal Article] Generation of an abasic site in an oligonucleotide by using acid-labile 1-deaza-2'-deoxyguanosine and its application to postsynthetic modification.2005
- Author(s)
  Kojima, N.
- Journal Title
  
  Organic Letters 7
  
  Pages: 709-712
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310157
[Journal Article] A new, but old, nucleoside analog : the first synthesis of l-deaza-2'-deoxy-guanosine and its properties as a nucleoside and as oligodeoxynucleotides.2003
- Author(s)
  Kojima, N.
- Journal Title
  
  Nucleic Acids Research 31
  
  Pages: 7175-7188
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310157
[Patent] 微小構造体、その作製方法およびそれを利用した分子検出方法2021
- Inventor(s)
  金賢徹、加藤大、小島直、山村昌平、鎌田智之
- Industrial Property Rights Holder
  国立研究開発法人産業技術総合研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20H02597
[Patent] 核酸の液中固定化剤2017
- Inventor(s)
  栗田僚二、小島直、栗之丸隆章
- Industrial Property Rights Holder
  栗田僚二、小島直、栗之丸隆章
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-033930
- Filing Date
  2017-02-24
- Data Source
  KAKENHI-PROJECT-15K14933
[Presentation] 微小曲面電極を用いた電気化学発光による非接着細胞表面分子検出技術の改良2024
- Author(s)
  佐々木太朗、内山皐生、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  第71回応用物理学会春季学術講演会
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] Detection of surface molecules on non-adherent cells based on electrochemiluminescence2023
- Author(s)
  佐々木太朗、内山皐生、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  Biosensors2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] Application of electrochemiluminescence with cup-shaped microelectrodes for detection of cell surface molecules2023
- Author(s)
  佐々木太朗、内山皐生、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  The 61th Annual Meeting of the Biophysical Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] 電気化学発光の非接着細胞表面分子検出への適用2023
- Author(s)
  佐々木太朗、内山皐生、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  日本応用物理学会第84回秋季学術講演会
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] Development of a technology to detect surface molecules on non-adherent cells by using Cup-shaped microelectrodes2022
- Author(s)
  佐々木太朗、内山皐生、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  The 60th Annual Meeting of the Biophysical Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] カップ型微小電極を用いた非接着細胞表面分子計測技術の開発2022
- Author(s)
  佐々木太朗、内山皐生、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  第69回応用物理学会春季学術講演会
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] 電気化学発光計測によるがん細胞表面発現マーカー分子検出技術の開発2021
- Author(s)
  内山皐生、栗山愛理、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  第82回応用物理学会秋季学術講演会
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] Detection of target biomolecules expressed on a cell surface based on electrochemiluminescence by using cup-shaped microelectrode2021
- Author(s)
  栗山愛理、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  Biosensors 2021, 31st Anniversary World congress on Biosensors
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] カップ形状微小電極への細胞捕捉と電気化学発光計測による細胞表面発現分子検出技術の開発2020
- Author(s)
  栗山愛理、内山皐生、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  日本応用物理学会第81回秋季学術講演会
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] Electrochemiluminescence-Based Detection of Cell Surface Biomolecules by Using Cup-Shaped Microelectrodes2020
- Author(s)
  栗山愛理、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  PRiME2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] NITROGEN-MUSTARD COATED MAGNETIC BEADS FOR HYBRIDIZATION AND ELUTION-FREE CIRCULATING TUMOR DNA DETECTION2019
- Author(s)
  Benediktus Nixon Hapsianto,小島直、栗田僚二,Hitoshi Yamagata,Hiroyuki Fujita,Teruo Fujii,Soo Hyeon Kim
- Organizer
  MicroTAS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03084
[Presentation] Immunochemical Assessment of 5-Methylcytosine and 5-Hydroxymethylcytosine Using Nitrogen Mustard Modified Linkers2019
- Author(s)
  小島直、須田友美、栗之丸隆章、栗田僚二
- Organizer
  The 46th International Symposium on Nucleic Acids Chemistry, The 3rd Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03084
[Presentation] Immunochemical Sensing of Epigenomic Modification Using An Alkylating Immobilization Linker2017
- Author(s)
  Takaaki Kurinomaru, Naoshi Kojima, Ryoji Kurita
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry / The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Data Source
  KAKENHI-PROJECT-17H03084
[Presentation] Immunochemical Sensing of Epigenomic Modification Using An Alkylating Immobilization Linker2017
- Author(s)
  栗之丸隆章、小島直、栗田僚二
- Organizer
  第44回国際核酸化学シンポジウム（ISNAC2017、日本核酸科学会第1回年会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14933
[Presentation] エピゲノムのオンチップ分析に向けたアルキル化リンカーの創成2017
- Author(s)
  栗田僚二, 栗之丸隆章, 小島直
- Organizer
  化学とマイクロ・ナノシステム学会第36回研究会
- Data Source
  KAKENHI-PROJECT-17H03084
[Presentation] 抗がん剤を有する新規リンカー分子を用いたメチル化DNA免疫センサーの開発2017
- Author(s)
  栗之丸隆章、小島直、吉岡恭子、栗田僚二
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学日吉キャンパス（神奈川県横浜市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K14933
[Presentation] Development of novel chemical probes to detect abasic sites in DNA2009
- Author(s)
  小島直
- Organizer
  6^<th> International Symposium on Nucleic Acids Chemistry and 36^<th> Symposium on Nucleic Acids Chemistry
- Place of Presentation
  岐阜県高山市
- Year and Date
  2009-09-29
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] Development of novel chemical probes to detect abasic sites in DNA2009
- Author(s)
  小島直、小松知志恵、三上暁子、大塚榮子、小松康雄
- Organizer
  第6回国際核酸化学シンポジウム
- Place of Presentation
  岐阜県高山市
- Year and Date
  2009-09-29
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] DNA脱塩基部位に高効率で反応する試薬の開発2009
- Author(s)
  小島直、小松知志恵、三上暁子、大塚榮子、小松康雄
- Organizer
  日本環境変異原学会第38回大会
- Place of Presentation
  静岡県清水市
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] Comparison of the chemical properties of a novel amino-linker with various aminomodifications2008
- Author(s)
  小島直
- Organizer
  第35回国際核酸化学シンポジウム
- Place of Presentation
  京都大学
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] Construction of an aminoxy derivative for RNA and DNA labeling2008
- Author(s)
  小松康雄、小島直、小松知志恵、三上暁子、杉野麻衣子、大塚榮子
- Organizer
  第35回核酸化学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] 新規アミノ化試薬の開発と、固相上でのオリゴヌクレオチド修飾反応への応用2008
- Author(s)
  小島直
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜大学
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] 新規アミノ化試薬の開発と, 固相上でのオリゴヌクレオチド修飾反応への応用2008
- Author(s)
  小島直、小松知志恵、三上暁子、杉野麻衣子、大塚榮子、小松康雄
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜県岐阜市
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] Comparison of the chemical properties of a novel amino-linker with various amino modifications2008
- Author(s)
  小島直、小松知志恵、三上暁子、杉野麻衣子、大塚榮子、小松康雄
- Organizer
  第35回核酸化学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20710179

1. KOMATSU Yasuo (30271670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. UEDE Toshimitsu (00160185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KON Shigeyuki (90344499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Mitani Yasuo (10358103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KURITA RYOJI (50415676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. Kim Hyonchol (70514107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. 大塚榮子 (80028836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 吉岡恭子 (50358321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 冨田峻介 (50726817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 栗之丸隆章 (50769693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 加藤大 (80533190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
12. 山村昌平 (50432141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
13. 中村史 (40357661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kojima Naoshi 小島 直

KOJIMA Naoshi 小島 直

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Use of bioluminescence to improve the sensitivity of gene detection technologyPrincipal Investigator

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Detection of target molecules expressed on a cell surface based on electrochemiluminescence

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Epigenome analysis on an array device for single cell / genome

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Novel molecular mechanisms of luminous fireworm

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Building up the bioluminescence molecule on the nucleic acid sequence and its application to gene detection technologyPrincipal Investigator

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Synthesis of novel chemical ligand that selectively bind to the unstabilized base pairs formed in DNAPrincipal Investigator

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分子間相互作用を利用したRNA末端部位標識化試薬の開発Principal Investigator

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非天然型ヌクレオシドの合成と、これを利用した核酸合成酵素認識機構の解析Principal Investigator

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Investigation of regulatory mechanism of homeostasis using functional nucleic acids.

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[Journal Article] Development of gapmer antisense oligonucleotide with deoxyribonucleic guanidine (DNG) modifications2019

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[Journal Article] Immobilization of DNA on Biosensing Devices with Nitrogen Mustard Modified Linkers2019

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[Journal Article] Sequential Assessment of Multiple Epigenetic Modifications of Cytosine in Whole Genomic DNA by Surface Plasmon Resonance2019

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[Journal Article] Immobilization of DNA with nitrogen mustard-biotin conjugate for global epigenetic analysis2018

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[Journal Article] An alkylating immobilization linker for immunochemical epigenetic assessment2017

Kojima Naoshi 小島直

KOJIMA Naoshi 小島直