TEZUKA Hiroyuki 手塚裕之

… Alternative Names

Tezuka Hiroyuki 手塚裕之

手塚裕之テヅカヒロユキ

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Researcher Number	30375258
Other IDs
External Links
Affiliation (Current)	2025: 藤田医科大学, オープンファシリティセンター, 講師
Affiliation (based on the past Project Information) *help	2021: 藤田医科大学, オープンファシリティーセンター, 講師 2021: 藤田医科大学, 研究推進本部オープンファシリティーセンター, 講師 2019 – 2020: 藤田医科大学, 共同利用研究設備サポートセンター, 講師 2015: 星薬科大学, 先端生命科学研究センター, 特任准教授 2009 – 2014: Tokyo Medical and Dental University, 難治疾患研究所, 助教 2007 – 2008: Akita University, 医学部, 助教 2005: 秋田大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related Except Principal Investigator Immunology / Biological Sciences
Keywords	Principal Investigator IgA / 樹状細胞 / TGF-β / plasmacytoid DC / Tip-DC / IgA腎症 / 腸内細菌 / 腸管関連リンパ組織 / クラススイッチ / TGF-beta … More / 免疫寛容 / 腸管上皮細胞 / 炎症性腸疾患 / 腸内常在菌 / オートファジー / Type I IFN / type I IFN / plasmacytoid D / Iga / HIGAマウス / 抗体 … More Except Principal Investigator Cytotoxic T lymphocytes / Dendritic cell / Nod1 / Endotoxin shock / Cytotoxic T lymphocyte / dendritic cell / Cross-priming / NOD1 / 抗原 / 肉芽腫 / 炎症性細胞 / Th1細胞 / IFN-γ / I型IFNs / IL-15 / IRF-3 Less

Regulation of TGF-b-dependent class switching by intestinal dendritic cellsPrincipal Investigator
- Principal Investigator
  
  Tezuka Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Fujita Health University
A conditioning machinery of dendritic cells by epithelial cells in the gutPrincipal Investigator
- Principal Investigator
  
  TEZUKA HIROYUKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hoshi University
  Tokyo Medical and Dental University
Regulation of gut mucosal homeostasis by autophagy in dendritic cellsPrincipal Investigator
- Principal Investigator
  
  TEZUKA Hiroyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
Regulatory mechanism of IgA production by plasmacytoid dendritic cells and its therapeutic application for IgA nephrophathyPrincipal Investigator
- Principal Investigator
  
  TEZUKA Hiroyuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
Nod1-mediated regulation of immunological homeostasis
- Principal Investigator
  
  SATO Taku, TADA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Akita University
Regulatory mechanism of IgA production by mucosal Tip-DC and its therapeutic application for IgA nephropathy.Principal Investigator
- Principal Investigator
  
  TEZUKA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Akita University
マクロファージ機能の人為的制御によるリーシュマニア症治療法の確立
- Principal Investigator
  
  樗木俊聡
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University

[Book] 免疫の事典 (分担：腫瘍壊死因子)2012
- Author(s)
  手塚裕之、樗木俊聡
- Total Pages
  488
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23790528
[Book] k.樹状細胞(2)機能2011
- Author(s)
  手塚裕之,安部由紀子,樗木俊聡
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23790528
[Book] 腫瘍壊死因子2011
- Author(s)
  手塚裕之,樗木俊聡
- Total Pages
  245
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23790528
[Book] 食品免疫アレルギーの事典 (分担：k. 樹状細胞、2. 機能)2011
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Total Pages
  488
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23790528
[Book] 腸内共生系のバイオサイエンス (分担：5.3 分泌抗体)2011
- Author(s)
  手塚裕之、樗木俊聡
- Total Pages
  312
- Publisher
  丸善出版
- Data Source
  KAKENHI-PROJECT-23790528
[Book] 分泌抗体2011
- Author(s)
  手塚裕之,樗木俊聡
- Publisher
  丸善出版
- Data Source
  KAKENHI-PROJECT-23790528
[Book] 粘膜系樹状細胞(誘導組織) (清野宏編) 臨床粘膜免疫学2010
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Publisher
  シナジー、東京
- Data Source
  KAKENHI-PROJECT-21790459
[Book] 粘膜系樹状細胞(誘導組織)(清野宏編)(臨床粘膜免疫学)東京2010
- Author(s)
  手塚裕之
- Publisher
  シナジー
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] D-allose enhances the efficacy of hydroxychloroquine against Lewis lung carcinoma cell growth by inducing autophagy2022
- Author(s)
  Kyoka Yamazaki、Masato Hoshi、Hiroyuki Tezuka、Nanaka Morita、Masaya Hirayama、Fumiaki Sato、Sayaka Yoshida、Kuniaki Saito
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 6 Pages: 117-117
- DOI
  10.3892/or.2022.8328
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-20K07432
[Journal Article] Tumor suppression and improvement in immune systems by specific activation of dopamine D1-receptor-expressing neurons in the nucleus accumbens2022
- Author(s)
  Sato Daisuke、Hamada Yusuke、Narita Michiko、Mori Tomohisa、Tezuka Hiroyuki、Suda Yukari、Tanaka Kenichi、Yoshida Sara、Tamura Hideki、Yamanaka Akihiro、Senba Emiko、Kuzumaki Naoko、Narita Minoru
- Journal Title
  
  Molecular Brain
  
  Volume: 15 Issue: 1 Pages: 17-17
- DOI
  10.1186/s13041-022-00902-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-18H02900, KAKENHI-PROJECT-18K07372
[Journal Article] 3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice2021
- Author(s)
  Hoshi Masato、Kubo Hisako、Ando Tatsuya、Tashita Chieko、Nakamoto Kentaro、Yamamoto Yasuko、Tezuka Hiroyuki、Saito Kuniaki
- Journal Title
  
  ImmunoHorizons
  
  Volume: 5 Issue: 6 Pages: 523-534
- DOI
  10.4049/immunohorizons.2100028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-20K07432
[Journal Article] Direct evidence that the brain reward system is involved in the control of scratching behaviors induced by acute and chronic itch2021
- Author(s)
  Setsu T, Hamada Y, Oikawa D, Mori T, Ishiuji Y, Sato D, Narita M, Miyazaki S, Furuta E, Suda Y, Sakai H, Ochiya T, Tezuka H, Iseki M, Inada E, Yamanaka A, Kuzumaki N, Narita M.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 534 Pages: 624-631
- DOI
  10.1016/j.bbrc.2020.11.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-19H05016, KAKENHI-PUBLICLY-20H05061, KAKENHI-PROJECT-18H02523
[Journal Article] 粘膜関連リンパ組織：粘膜免疫を司るリンパ装置2021
- Author(s)
  1. 柴田侑依、日比谷睦子、手塚裕之
- Journal Title
  
  呼吸器内科
  
  Volume: 40 Pages: 615-621
- NAID
  40022777379
- Data Source
  KAKENHI-PROJECT-19K07614
[Journal Article] Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy2021
- Author(s)
  Taniguchi-Ikeda Mariko、Koyanagi-Aoi Michiyo、Maruyama Tatsuo、Takaori Toru、Hosoya Akiko、Tezuka Hiroyuki、Nagase Shotaro、Ishihara Takuma、Kadoshima Taisuke、Muguruma Keiko、Ishigaki Keiko、Sakurai Hidetoshi、Mizoguchi Akira、Novitch Bennett G.、Toda Tatsushi、Watanabe Momoko、Aoi Takashi
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 10 Pages: 103140-103140
- DOI
  10.1016/j.isci.2021.103140
- NAID
  120007170807
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-21H03812, KAKENHI-PROJECT-21K19457, KAKENHI-PROJECT-20H00526, KAKENHI-PROJECT-23K21430
[Journal Article] Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2020
- Author(s)
  Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, Yamamoto Y, Tezuka H, Tomita H, Hara A, Saito K.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 26 Issue: 9 Pages: 918-932
- DOI
  10.3748/wjg.v26.i9.918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-19K08667, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873
[Journal Article] Propolis induces Ca<sup>2+</sup> signaling in immune cells2019
- Author(s)
  Adachi T, Yoshikawa S, Tezuka H, Tsuji NM, Ohteki T, Karasuyama H, Kumazawa T.
- Journal Title
  
  Bioscience of Microbiota, Food and Health
  
  Volume: 38 Issue: 4 Pages: 141-149
- DOI
  10.12938/bmfh.19-011
- NAID
  130007738832
- ISSN
  2186-3342
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-19K07620, KAKENHI-PUBLICLY-18H05028, KAKENHI-PROJECT-19H01024, KAKENHI-PROJECT-19H01025, KAKENHI-PROJECT-17H06170
[Journal Article] Regulation of IgA production by intestinal dendritic cells and related cells.2019
- Author(s)
  Tezuka H, and Ohteki T.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 10 Pages: 1891-1891
- DOI
  10.3389/fimmu.2019.01891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PUBLICLY-18H05028, KAKENHI-PROJECT-19H01024
[Journal Article] Cytosine-phosphorothionate- guanine oligodeoxynucleotides exacerbates hemophagocytosis by inducing tumor necrosis factor-α production in mice after bone marrow transplanation.2016
- Author(s)
  Liu J, Guo YM, Onai N, Ohyagi H, Hirokawa M, Takahashi N, Tagawa H, Ubukawa K, Kobayahi I, Tezuka H, Minamiya Y, Ohteki T, and Sawada K.
- Journal Title
  
  Biol Blood Marrow Transplant 2015
  
  Volume: 印刷中 Issue: 4 Pages: 627-636
- DOI
  10.1016/j.bbmt.2015.12.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15150, KAKENHI-PUBLICLY-15H01485, KAKENHI-PUBLICLY-15H01508, KAKENHI-PROJECT-26253029, KAKENHI-PROJECT-15H04717, KAKENHI-PROJECT-25460586, KAKENHI-PROJECT-26461439, KAKENHI-PROJECT-15K08639
[Journal Article] Immunomodulatory effects of soybeans and processed soy food compounds.2015
- Author(s)
  Hiroyuki Tezuka, and Shinjiro Imai.
- Journal Title
  
  Recent Patents on Food, Nutrition and Agriculture
  
  Volume: 7 Pages: 92-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460586
[Journal Article] IgA生産を制御する樹状細胞サブセット2014
- Author(s)
  手塚裕之、安部由紀子、黒田聖子、樗木俊聡
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 62 Pages: 593-599
- Data Source
  KAKENHI-PROJECT-25460586
[Journal Article] CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin.2013
- Author(s)
  Ichikawa, A., Kuba, K., Morita, M., Chida, S., Tezuka, H.
- Journal Title
  
  Am. J. Respir. Crit.Care Med.
  
  Volume: 187 Issue: 1 Pages: 65-77
- DOI
  10.1164/rccm.201203-0508oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790528, KAKENHI-PROJECT-25460586
[Journal Article] T細胞非依存性IgA生産における樹状細胞の役割2012
- Author(s)
  手塚裕之,安部由紀子,樗木俊聡
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 58(3) Pages: 283-289
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] T細胞非依存性IgA生産における樹状細胞の役割2012
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫アレルギー科
  
  Volume: 58 Pages: 283-289
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] 樹状細胞による抗体生産制御2012
- Author(s)
  手塚裕之,安部由紀子,樗木俊聡
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 58(5) Pages: 525-533
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] pDCによる新たなIgA産生誘導メカニズム2012
- Author(s)
  樗木俊聡,手塚裕之
- Journal Title
  
  医学のあゆみ
  
  Volume: 240(2) Pages: 182-183
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] 腸管粘膜防御機構を担うIgA抗体の新たな産生機構 (形質細胞様樹状細胞のユニークな役割)2012
- Author(s)
  樗木俊聡、手塚裕之
- Journal Title
  
  炎症と免疫
  
  Volume: 20巻 Pages: 178-182
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] pDCによる新たなIgA産生誘導メカニズム2012
- Author(s)
  樗木俊聡、手塚裕之
- Journal Title
  
  医学のあゆみ
  
  Volume: 240巻 Pages: 182-183
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] 樹状細胞による抗体生産制御2012
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫アレルギー科
  
  Volume: 58 Pages: 525-533
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction.2011
- Author(s)
  Tezuka, H., Abe, Y., Asano, J., Sato, T., Liu, J., Iwata, M., Ohteki, T.
- Journal Title
  
  Immunity 34
  
  Pages: 247-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] T細胞非依存性IgA生産誘導における形質細胞様樹状細胞の質的優位性2011
- Author(s)
  樗木俊聡、手塚裕之
- Journal Title
  
  細胞工学 30
  
  Pages: 376-380
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] 形質細胞様樹状細胞によるT細胞非依存性IgA生産制御2011
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  臨床免疫アレルギー科
  
  Volume: 55巻 Pages: 687-692
- NAID
  40018904451
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] pDCによる新たなIgA生産誘導の仕組み2011
- Author(s)
  樗木俊聡、手塚裕之
- Journal Title
  
  感染炎症免疫
  
  Volume: 41巻 Pages: 83-84
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] T細胞非依存性IgA生産誘導における形質細胞様樹状細胞の質的優位性2011
- Author(s)
  樗木俊聡,手塚裕之
- Journal Title
  
  細胞工学
  
  Volume: 30 Pages: 376-380
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction2011
- Author(s)
  TEZUKA, H., ABE, Y., ASANO, J., SATO, T., LIU, J., IWATA, M., and OHTEKI, T.
- Journal Title
  
  Immunity
  
  Volume: 34巻 Issue: 2 Pages: 247-257
- DOI
  10.1016/j.immuni.2011.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] 形質細胞様樹状細胞によるT細胞非依存性IgA生産制御2011
- Author(s)
  手塚裕之,安部由紀子,樗木俊聡
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 55(3) Pages: 678-692
- NAID
  40018904451
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction2011
- Author(s)
  Tezuka, H.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 247-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] T細胞非依存性IgA生産誘導機構における形質細胞様樹状細胞の質的優位性2011
- Author(s)
  樗木俊聡、手塚裕之
- Journal Title
  
  細胞工学
  
  Volume: 30巻 Pages: 376-380
- Data Source
  KAKENHI-PROJECT-23790528
[Journal Article] Regulation of intestinal homeostasis by dendritic cells2010
- Author(s)
  Tezuka, H.
- Journal Title
  
  Immunological review
  
  Volume: 234 Pages: 247-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] A gas governing mucosal immunity2010
- Author(s)
  Tezuka, H.
- Journal Title
  
  Vaccine
  
  Volume: 28 Pages: 8039-8040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] A gas governing mucosal immunity.2010
- Author(s)
  Tezuka, H., Ohteki, T.
- Journal Title
  
  Vaccine 28
  
  Pages: 8039-8040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] Regulation of intestinal homeostasis by dendritic cells.2010
- Author(s)
  Tezuka, H., Ohteki, T.
- Journal Title
  
  Immunological Review 234
  
  Pages: 247-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] Regulation of intestinal homeostasis by dendritic cells2010
- Author(s)
  手塚裕之
- Journal Title
  
  Immunological Reviews 234
  
  Pages: 247-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] Role of SIRPα in regulation of mucosal immunity in the intestine.2010
- Author(s)
  Kanazawa, Y., Saito, Y., Supriatna, Y., Tezuka, H., Kotani, T., Murata, Y., Okazawa, H., Ohnishi, H., Kinouchi, Y.,Nojima, Y., Ohteki, T., Shimosegawa, T., Matozaki, T.
- Journal Title
  
  Genes Cells 15
  
  Pages: 1189-1200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] TNF/iNOS 産生DCとIgA分泌2010
- Author(s)
  樗木俊聡、手塚裕之
- Journal Title
  
  医学のあゆみ 234
  
  Pages: 453-457
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] 消化管粘膜におけるIgA生産機構2009
- Author(s)
  手塚裕之
- Journal Title
  
  炎症と免疫 17
  
  Pages: 86-92
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] 粘膜関連リンパ組織におけるT細胞非依存性 IgAクラススイッチ誘導機構2009
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  臨床免疫.アレルギー科 52
  
  Pages: 422-430
- NAID
  40016880979
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] 消化管粘膜におけるIgA 生産機構2009
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  炎症と免疫 17
  
  Pages: 568-574
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] 粘膜関連リンパ組織におけるT細胞非依存性IgAクラススイッチ誘導機構2009
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫・アレルギー科 52
  
  Pages: 422-430
- NAID
  40016880979
- Data Source
  KAKENHI-PROJECT-21790459
[Journal Article] 粘膜樹状細胞によるIgAクラススイッチ誘導機構2008
- Author(s)
  安部由紀子、手塚裕之、樗木俊聡
- Journal Title
  
  感染・炎症・免疫 38
  
  Pages: 271-274
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] IgAクラススイッチを誘導するバイエル板樹状細胞2008
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 216-221
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] 腸管でのIgA生産を司るTNF/iNOS生産性樹状細胞とその機能2008
- Author(s)
  手塚裕之
- Journal Title
  
  生体の科学 59
  
  Pages: 268-274
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] IgAクラススイッチを誘導するパイエル板樹状細胞2008
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 216-221
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 腸管における樹状細胞のトラフィヅキングとIgA生産誘導機構2008
- Author(s)
  手塚, 裕之
- Journal Title
  
  臨床免疫・アレルギー科 49
  
  Pages: 10-15
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 樹状細胞によるIgA生産誘導機構の新知見2008
- Author(s)
  樗木俊聡、安部由紀子、手塚裕之
- Journal Title
  
  炎症と免疫 16
  
  Pages: 209-214
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] Effective clearance of intracellular Leishmania major in vivo requires Pten in macrophages2008
- Author(s)
  Kuroda, S., Nishio, M., Sasaki, T., Horie, Y., Kawahara, K., Sasaki, M., Natsui, M., Matozaki, T., Tezuka, H., Ohteki, T., Forster, I., Mak, T.W., Nakano, T., and Suzuki, A.
- Journal Title
  
  Eur. J. Immunol 38
  
  Pages: 1331-1340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] 腸管でのIgA生産を司るTNF/iNos生産性樹状細胞とその機能2008
- Author(s)
  手塚裕之
- Journal Title
  
  生体の科学 59
  
  Pages: 268-274
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 腸管における樹状細胞のトラフィッキングとIgA生産誘導機構2008
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫・アレルギー科 49
  
  Pages: 10-15
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] 腸管における樹状細胞のトラフィッキングとIgA生産誘導機構2008
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  臨床免疫・アレルギー科 49
  
  Pages: 10-15
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] IgAクラススイッチを誘導するバイエル板樹状細胞2008
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 216-221
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 消化管粘膜での免疫応答における樹状細胞の役割-小腸粘膜樹状細胞によるIgAクラススイッチ制御2008
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  実験医学 26
  
  Pages: 3236-3242
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 消化管粘膜での免疫応答における樹状細胞の役割-小腸粘膜樹状細胞によるIgAクラススイッチ制御2008
- Author(s)
  手塚裕之
- Journal Title
  
  実験医学 26
  
  Pages: 3236-3242
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 腸管粘膜樹状細胞によるIgAクラススイッチ制御-腸内常在菌の役割2008
- Author(s)
  手塚裕之
- Journal Title
  
  医学めあゆみ 227
  
  Pages: 326-331
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 腸管粘膜樹状細胞によるIgAクラススイッチ制御-腸内常在菌の役割2008
- Author(s)
  手塚裕之
- Journal Title
  
  医学のあゆみ 227
  
  Pages: 326-331
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] Effective clearance of intracellular Leishmania major in vivo requires Pten in macrophages. Eur.2008
- Author(s)
  Kuroda, S., Nishio, M., Sasaki, T., Horie, Y., Kawahara, K., Sasaki, M., Natsui, M., Matozaki, T., Tezuka, H., Oheteki, T., Forster, I, Mak, TW, Nakano, T, and Suzuki, A
- Journal Title
  
  J. Immunol 38
  
  Pages: 1331-1340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 腸管における樹状細胞のトラフィッキングとIgA生産誘導機構2008
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫・アレルギー科 49
  
  Pages: 10-15
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 腸管でのIgA生産を司るTNF/iNOS生産性樹状細胞とその機能2008
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  生体の科学 59
  
  Pages: 268-274
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 消化管粘膜での免疫応答における樹状細胞の役割-小腸粘膜樹状細胞によるIgAクラススイッチ制御2008
- Author(s)
  手塚裕之
- Journal Title
  
  実験医学 26
  
  Pages: 3236-3242
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] 腸管粘膜樹状細胞によるIgAクラススイッチ制御-腸内常在菌の役割2008
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  医学のあゆみ 227
  
  Pages: 326-331
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 粘膜TiP-DCによるIgA生産誘導機構.2007
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫・アレルギー科 47
  
  Pages: 619-624
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells.2007
- Author(s)
  Tezuka, H.
- Journal Title
  
  Nature 448
  
  Pages: 929-933
- NAID
  40016204559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 樹状細胞によるIgAクラススイッチ誘導機構2007
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫・アレルギー科 48
  
  Pages: 230-235
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] 粘膜TiP-DCによるIgA生産誘導機構2007
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  臨床免疫・アレルギー科 47
  
  Pages: 619-624
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] Regulation of IgA production by naturally occurring TNF/iNOSproducing dendritic cells2007
- Author(s)
  Tezuka, H., Abe, Y., Iwata, M, Takeuchi, H., Ishikawa, H., Matsushita, M., Shiohara, T., Akira, S., and Ohteki, T.
- Journal Title
  
  Nature 448
  
  Pages: 929-933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] 樹状細胞によるIgAクラススイッチ誘導機構2007
- Author(s)
  手塚, 裕之
- Journal Title
  
  臨床免疫・アレルギー科 48
  
  Pages: 230-235
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells.2007
- Author(s)
  Tezuka, H.
- Journal Title
  
  Nature 448
  
  Pages: 929-933
- NAID
  40016204559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] 粘膜Tip-DCによるlgA生産誘導機構.2007
- Author(s)
  手塚, 裕之
- Journal Title
  
  臨床免疫・アレルギー科 47
  
  Pages: 619-624
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] Regulation of IgA production by naturally occurring TNF/iNOS- producing dendritic cells.2007
- Author(s)
  Tezuka, H. Abe, Y., Iwata, M, Takeuchi, H., Ishikawa, H., Matsushita, M., Shiohara, T., Akira, S., and Ohteki, T.
- Journal Title
  
  Nature 448
  
  Pages: 929-933
- NAID
  40016204559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 樹状細胞によるIgAクラススイッチ誘導機構2007
- Author(s)
  手塚裕之、安部由紀子、樗木俊聡
- Journal Title
  
  臨床免疫・アレルギー科 48
  
  Pages: 230-235
- Data Source
  KAKENHI-PROJECT-19790353
[Journal Article] 樹状細胞が生産するサイトカインによるB細胞の機能調節2005
- Author(s)
  手塚裕之
- Journal Title
  
  臨床免疫 44(1)
  
  Pages: 109-112
- NAID
  40006859398
- Data Source
  KAKENHI-PROJECT-16017212
[Presentation] 高食塩負荷による高血圧および情動・認知機能障害におけるPGE2/EP1シグナルの関与2021
- Author(s)
  窪田悠力、國澤和生、長谷川眞也、倉橋仁美、手塚裕之、釘田雅則、長尾静子、齋藤邦明、鍋島俊隆、毛利彰宏
- Organizer
  第15回日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] 高食塩負荷により惹起される高血圧および行動異常は末梢炎症反応を伴う2021
- Author(s)
  窪田悠力、毛利彰宏、國澤和生、長谷川眞也、倉橋仁美、山本康子、手塚裕之、釘田雅則、長尾静子、齋藤邦明、鍋島俊隆
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] 悪性黒色腫移植担がんマウスにおける”痛み刺激”負荷による脾臓リンパ球の変化を伴った免疫変容の解析2021
- Author(s)
  田中謙一、濱田祐輔、牟田武尊、渡邊諒、成田道子、佐藤大介、手塚裕之、山中章弘、落合孝広、葛巻直子、成田年
- Organizer
  第14回日本緩和医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] Involvement of cerebellum blood-brain barrier disruption in the depression-like behaviors induced by chronic social defeat stress2021
- Author(s)
  Aika Kosuge、Kazuo Kunisawa、Hiroyuki Tezuka、Masato Hoshi、Nanaka Morita、Tomoki Kawai、Yasuko Yamamoto、Kuniaki Saito、Toshitaka Nabeshima、Akihiro Mouri
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] C線維特異的知覚神経活性化制御による脾臓リンパ球における免疫変容解析2021
- Author(s)
  牟田武尊、田中謙一、濱田祐輔、成田道子、佐藤大介、山下健介、手塚裕之、山中章弘、落合孝広、葛巻直子、成田年
- Organizer
  第144回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] 人為的な知覚神経の活性化に伴う末梢免疫細胞の質的変化2020
- Author(s)
  山下健介, 近藤貴茂, 濱田祐輔, 田中謙一, 佐藤大介, 飯塚麻純, 清水遥奈, 手塚裕之, 山中章弘, 葛巻直子, 成田年.
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] 側坐核中型有棘神経細胞が担う中枢性制御機構の解明2020
- Author(s)
  佐藤大介, 成田道子, 濱田祐輔, 手塚裕之, 落合孝広, 葛巻直子, 山中章弘, 成田年.
- Organizer
  日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] New everolimus administration targeting the prevention of the development of antibody-mediated rejection considering the comparison of growth and survival in IgG and IgG memory B cells.2020
- Author(s)
  Matsuda Y, Tezuka H, Imamura R, Takahata S.
- Organizer
  The 2020 American Transplant Congress (ATC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] 腸管樹状細胞によるIgA生産制御機構2019
- Author(s)
  手塚裕之
- Organizer
  第28回内毒素・LPS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07614
[Presentation] TLR9 signaling exerts HPS in BMT mice and is effectively treated through TNF-α inhibition2015
- Author(s)
  劉嘉嘉, 郭永梅, 大八木秀明, 広川誠, 高橋直人, 鵜生川久美, 小林五十鈴, 南谷佳弘, 手塚裕之, 小内伸幸, 樗木俊聡, 澤田賢一
- Organizer
  日本血液学会学術集会
- Place of Presentation
  ホテル日航金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25460586
[Presentation] TNF/iNOS-producing dendritic cells are originated from inflammatory monocytes and regulate gut IgA production.2013
- Author(s)
  Tezuka, H., and Ohteki, T.
- Organizer
  第42回日本免疫学会総会学術集会記録
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25460586
[Presentation] Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction2012
- Author(s)
  Tezuka, H.
- Organizer
  International Symposium on Dendritic Cells (DC2012)
- Place of Presentation
  韓国　テグ
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction2012
- Author(s)
  Tezuka, H.
- Organizer
  International Symposium on Molecular Cell Biology of Macrophages 2012
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction2012
- Author(s)
  Tezuka, H.
- Organizer
  20th International Symposium on Molecular Cell Biology of Macrophages 2012 (MMCB2012).
- Place of Presentation
  Tokyo, Japan.
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] Prominent role for plasmacytoid dendritic cells inmucosal T cell-independent IgA induction2012
- Author(s)
  Tezuka, H.
- Organizer
  The 12th International Symposium on Dendritic Cells (DC2012)
- Place of Presentation
  Daegu, Korea.
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] 形質細胞様樹状細胞はT細胞に依存しない優れたIgA産生能力を備えている2011
- Author(s)
  手塚裕之,樗木俊聡
- Organizer
  第21回日本樹状細胞研究会
- Place of Presentation
  福岡
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] T細胞非依存性IgA生産誘導における形質細胞様樹状細胞の質的優位性2011
- Author(s)
  手塚裕之
- Organizer
  第32回和漢医薬学総合研究所特別セミナー和漢薬治療のターゲットとしての粘膜免疫機構
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction2011
- Author(s)
  Tezuka, H.
- Organizer
  第40回日本免疫学会総会・学術集会記録
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] 腸内細菌と粘膜免疫系の相互作用に関する新知見2010
- Author(s)
  手塚裕之
- Organizer
  第51回千葉造血幹細胞移植研究会
- Place of Presentation
  バーディーホテル(千葉)
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21790459
[Presentation] 腸内細菌と粘膜免疫系との相互作用に関する新知見2010
- Author(s)
  手塚裕之
- Organizer
  第51回千葉造血幹細胞移植研究会
- Place of Presentation
  千葉
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21790459
[Presentation] Regulation of IgA production by natural ly occurring TNF/iNOS-producing dendritic cells.2009
- Author(s)
  Tezuka, H
- Organizer
  The 4th Stage Surface Barrier Immunology Study Group (SBARIS) 1st Meeting 「Immune Response at Mucosal Surface」
- Place of Presentation
  東京
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-19790353
[Presentation] Critical role for type I IFNs in pDC-induced T cell-independent IgA production.2009
- Author(s)
  Tezuka, H., Abe, Y., Ohteki, T.
- Organizer
  第39回日本免疫学会総会.学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21790459
[Presentation] Critical role for type I IFNs in pDC-induced T cell-independent IgA production2009
- Author(s)
  Tezuka, H.
- Organizer
  日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21790459
[Presentation] Regulation of IgA production by natural ly occurring TNF/iNOS-producing dendritic cells2009
- Author(s)
  Tezuka, H.
- Organizer
  The 4th Stage Surface Barrier Immunology Study Group (SBARIS) 1 st Meeting 「Immune Response at Mucosal Surface」
- Place of Presentation
  Tokyo
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-19790353
[Presentation] Critical role for pDCs in mucosal T cell-independent IgA production.2008
- Author(s)
  Tezuka, H.
- Organizer
  第38日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790353
[Presentation] Critical role for pDCs in mucosal T cell-independent IgA production2008
- Author(s)
  Tezuka, H.
- Organizer
  第38日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790353
[Presentation] Regulation of IgA production by naturally Occurring TNF/iNOS-producting dendritic cells.2007
- Author(s)
  Tezuka, H.
- Organizer
  第37回日本免疫学会Late breaking symposium
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19590489
[Presentation] Regulation of IgA production by naturally Occurring TNF/iNOS-producing dendritic cells.2007
- Author(s)
  Tezuka, H.
- Organizer
  第37回日本免疫学会Late breaking symposium
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19790353
[Presentation] Regulation of IgA production by naturally occurring TNF/iNOS- producting dendritic cells.2007
- Author(s)
  Tezuka, H.
- Organizer
  第37回日本免疫学会総会・学術集会Late breaking symposium
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19790353
[Presentation] Regulation of IgA production by mucosal CCL2^+ dendritic cells.2007
- Author(s)
  Tezuka, H.
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19590489
[Presentation] Regulation of IgA production by mucosal CCL2+ dendritic cells.2007
- Author(s)
  Tezuka, H. Abe, Y. and Ohteki, T.
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19790353
[Presentation] Regulation of IgA production by mucosal CCL2+ dendritic cells.2007
- Author(s)
  Tezuka, H.
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19790353
[Presentation] 形質細胞様樹状細胞はT細胞に依存しない優れたIgA産生誘導能力を備えている
- Author(s)
  手塚裕之、樗木俊聡
- Organizer
  第21回日本樹状細胞研究会
- Place of Presentation
  福岡コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] Autophagy-dependent regulation of intestinal homeostasis by dendritic cells
- Author(s)
  Hiroyuki Tezuka, Toshiaki Ohteki
- Organizer
  日本免疫学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25460586
[Presentation] Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction
- Author(s)
  TEZUKA, H., ABE., ASANO, J., SATO, T., LIU, J., IWATA, M., and OHTEKI, T.
- Organizer
  第40回日本免疫学会総会学術集会記録
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-23790528
[Presentation] T細胞非依存性IgA生産誘導における形質細胞様樹状細胞の質的優位性
- Author(s)
  手塚裕之
- Organizer
  第32回和漢医薬学総合研究所特別セミナー(招待講演)
- Place of Presentation
  富山県民会館
- Data Source
  KAKENHI-PROJECT-23790528

1. SATO Taku (40375259)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TADA Hiroyuki (70431632)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ONAI N. Obuyuki (50323605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 樗木俊聡 (50233200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 松田信治 (70199800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HOSHI Masato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TEZUKA Hiroyuki 手塚 裕之

Tezuka Hiroyuki 手塚 裕之

手塚 裕之 テヅカ ヒロユキ

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Co-Researchers

Regulation of TGF-b-dependent class switching by intestinal dendritic cellsPrincipal Investigator

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A conditioning machinery of dendritic cells by epithelial cells in the gutPrincipal Investigator

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Regulation of gut mucosal homeostasis by autophagy in dendritic cellsPrincipal Investigator

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Regulatory mechanism of IgA production by plasmacytoid dendritic cells and its therapeutic application for IgA nephrophathyPrincipal Investigator

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Nod1-mediated regulation of immunological homeostasis

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Regulatory mechanism of IgA production by mucosal Tip-DC and its therapeutic application for IgA nephropathy.Principal Investigator

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マクロファージ機能の人為的制御によるリーシュマニア症治療法の確立

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[Book] 免疫の事典 (分担：腫瘍壊死因子)2012

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[Book] k.樹状細胞(2)機能2011

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[Book] 腫瘍壊死因子2011

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[Book] 食品免疫 アレルギーの事典 (分担：k. 樹状細胞、2. 機能)2011

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[Book] 腸内共生系のバイオサイエンス (分担：5.3 分泌抗体)2011

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[Book] 分泌抗体2011

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[Book] 粘膜系樹状細胞(誘導組織) (清野宏編) 臨床粘膜免疫学2010

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TEZUKA Hiroyuki 手塚裕之

Tezuka Hiroyuki 手塚裕之

手塚裕之テヅカヒロユキ

[Book] 食品免疫アレルギーの事典 (分担：k. 樹状細胞、2. 機能)2011