Nishimoto Yoshinori 西本祥仁

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NISHIMOTO Yoshinori 西本祥仁

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Researcher Number	30398622
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 慶應義塾大学, 医学部(信濃町), 講師 2021: 慶應義塾大学, 医学部(信濃町), 助教 2014: 慶應義塾大学, 医学部, 特任助教 2012: 慶應義塾大学, 医学部, 助教 2011 – 2012: 慶應義塾大学, 医学部, 特任助教 2009 – 2010: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Neurology / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / 医学物理学・放射線技術学
Keywords	Principal Investigator ALS / TDP-43 / 核酸医薬 / DigiGait 解析システム / パラスペックル / 長鎖ノンコーディングRNA / 核内ＲＮＡ / 核膜タンパク質 / ノンコーディングRNA / 核内RNA … More / DigiGait解析システム / ゲノム編集マウス / RNA結合タンパク質 / FUS / 運動神経細胞 / 胚性幹細胞 (ES細胞) / ADAR2 / LIN28 / RNA編集 / マグネトフェクション / ES細胞 / 胚性幹細胞 / 筋萎縮性側索硬化症 / 運動神経細胞死 / 胚性幹細胞 (ES 細胞) / 筋萎縮性側索硬化症 (ALS) / alternative splicing / 筋萎縮性側索硬化症(ALS) / RNA / stress granule / aggresome / caspase-3 / ALS(筋萎縮性側索硬化症) … More Except Principal Investigator 前頭側頭型認知症 / 筋萎縮性側索硬化症 / 認知症 / ミクログリア / 遺伝子改変マウス / 炎症 / 神経変性疾患 / 蛍光蛋白質 / DNA傷害 / レポーター遺伝子 / 放射線 / p53 / ゲノム編集 / 神経幹細胞 / 幹細胞 Less

Investigations of a pathological mechanism on the GC / UG-rich RNA sequences in ALS using genome-edited mice to develop novel therapiesPrincipal Investigator
- Principal Investigator
  
  西本祥仁
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Keio University
Targeting microglia to elucidate the molecular pathogenesis of neurodegenerative diseases and establish therapeutic strategies.
- Principal Investigator
  
  伊東大介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Keio University
Establishment of the reporter stem cell lines capable of evaluating the cell influence by radiation.
- Principal Investigator
  
  IMAI TAKAO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医学物理学・放射線技術学
- Research Institution
  Keio University
Investigation of cellular toxicity induced by LIN28 in amyotrophic lateral sclerosisPrincipal Investigator
- Principal Investigator
  
  NISHIMOTO Yoshinori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Keio University
The characterization of TDP-43 aggregation in Amyotrophic Lateral Sclerosis (ALS)Principal Investigator
- Principal Investigator
  
  NISHIMOTO Yoshinori
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Keio University

All 2024 2023 2022 2021 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Depressive symptoms and carotid arteriosclerosis in very old people aged 85?years and older: A cross‐sectional study by the Kawasaki Aging and Wellbeing Project2024
- Author(s)
  Shikimoto Ryo、Sasaki Takashi、Abe Yukiko、Nishimoto Yoshinori、Hirata Takumi、Mimura Masaru、Arai Yasumichi
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 78 Issue: 3 Pages: 209-211
- DOI
  10.1111/pcn.13636
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07281, KAKENHI-PROJECT-23K28027
[Journal Article] Impact of Amyloid and Tau PET on Changes in Diagnosis and Patient Management2023
- Author(s)
  Shimohama S, Tezuka T, Keisuke T, Bun S, Tabuchi H, Seki M, Momota Y, Suzuki N, Morimoto A, Iwabuchi Y, Kubota M, Yamamoto Y, Sano Y, Shikimoto R, Funaki K, Mimura Y, Nishimoto Y, Ueda R, Jinzaki M, Nakahara J, Mimura M, Ito D
- Journal Title
  
  Neurology
  
  Volume: 100 Issue: 3
- DOI
  10.1212/wnl.0000000000201389
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07281, KAKENHI-PROJECT-20K07935, KAKENHI-PROJECT-23K21397
[Journal Article] Measurement of polydoctoring as a crucial component of fragmentation of care among patients with multimorbidity: Cross‐sectional study in Japan2023
- Author(s)
  Ando Takayuki、Sasaki Takashi、Abe Yukiko、Nishimoto Yoshinori、Hirata Takumi、Haruta Junji、Arai Yasumichi
- Journal Title
  
  Journal of General and Family Medicine
  
  Volume: 24 Issue: 6 Pages: 343-349
- DOI
  10.1002/jgf2.651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07281, KAKENHI-PROJECT-21K10356, KAKENHI-PROJECT-23K28027
[Journal Article] Prognostic significance of serum testosterone level in patients with castration‐resistant prostate cancer treated with cabazitaxel2023
- Author(s)
  Fujiwara Shinnosuke、Kosaka Takeo、Nishimoto Yoshinori、Kamisawa Ken、Watanabe Keitaro、Baba Yuto、Takeda Toshikazu、Matsumoto Kazuhiro、Oya Mototsugu
- Journal Title
  
  The Prostate
  
  Volume: 84 Issue: 1 Pages: 25-31
- DOI
  10.1002/pros.24620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07281
[Journal Article] “Missing-piece” sign with dural arteriovenous fistula at craniocervical junction: A case report2023
- Author(s)
  Tezuka Toshiki、Nukariya Tomonori、Katsumata Masahiro、Miyauchi Tsubasa、Tokuyasu Daiki、Azami Shunpei、Izawa Yoshikane、Nagoshi Narihito、Fujiwara Hirokazu、Mizutani Katsuhiro、Akiyama Takenori、Toda Masahiro、Nakahara Jin、Nishimoto Yoshinori
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 32 Issue: 7 Pages: 107152-107152
- DOI
  10.1016/j.jstrokecerebrovasdis.2023.107152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07281
[Journal Article] Status and physiological significance of circulating adiponectin in the very old and centenarians: an observational study2023
- Author(s)
  Sasaki Takashi、Nishimoto Yoshinori、Hirata Takumi、Abe Yukiko、Hirose Nobuyoshi、Takayama Michiyo、Takebayashi Toru、Okano Hideyuki、Arai Yasumichi
- Journal Title
  
  eLife
  
  Volume: 12 Pages: 86309-86309
- DOI
  10.7554/elife.86309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07281, KAKENHI-PROJECT-23K28027
[Journal Article] Association between multimorbidity, self-rated health and life satisfaction among independent, community-dwelling very old persons in Japan: longitudinal cohort analysis from the Kawasaki Ageing and Well-being Project2022
- Author(s)
  Ando Takayuki、Nishimoto Yoshinori、Hirata Takumi、Abe Yukiko、Takayama Midori、Maeno Takashi、Fujishima Seitaro、Takebayashi Toru、Arai Yasumichi
- Journal Title
  
  BMJ Open
  
  Volume: 12 Issue: 2 Pages: e049262-e049262
- DOI
  10.1136/bmjopen-2021-049262
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03055, KAKENHI-PROJECT-21K07281, KAKENHI-PROJECT-21K10356
[Journal Article] NEAT1 lncRNA and amyotrophic lateral sclerosis2021
- Author(s)
  Nishimoto Yoshinori、Nakagawa Shinichi、Okano Hideyuki
- Journal Title
  
  Neurochemistry International
  
  Volume: 150 Pages: 105175-105175
- DOI
  10.1016/j.neuint.2021.105175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03604, KAKENHI-PROJECT-21K07281
[Journal Article] ALDH2 p.E504K Variation and Sex Are Major Factors Associated with Current and Quitting Alcohol Drinking in Japanese Oldest Old2021
- Author(s)
  Sasaki Takashi、Nishimoto Yoshinori、Hirata Takumi、Abe Yukiko、Takebayashi Toru、Arai Yasumichi
- Journal Title
  
  Genes
  
  Volume: 12 Issue: 6 Pages: 799-799
- DOI
  10.3390/genes12060799
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03055, KAKENHI-PROJECT-20K07792, KAKENHI-PROJECT-21K07281
[Journal Article] Cellular toxicity induced by the 26-kDa fragment and amyotrophic lateral sclerosis (ALS)-associated mutant forms of TDP-43 in human embryonic stem cell-derived motor neurons.2013
- Author(s)
  Yoshinori Nishimoto
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Pages: 24-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791002
[Journal Article] Cellular toxicity induced by the 26-kDa fragment and amyotrophic lateral sclerosis (ALS)-associated mutant forms of TDP-43 in human embryonic stem cell-derived motor neurons2013
- Author(s)
  Yoshinori Nishimoto, Hirotaka J. Okano, Takao Imai, Aleksandra J. Poole, Norihiro Suzuki, Hans S. Keirstead, Hideyuki Okano
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1(1) Pages: 24-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791002
[Journal Article] The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis2013
- Author(s)
  Nishimoto, Y., Nakagawa, S., Hirose, T., Okano, H. J., Takao, M., Shibata, S., Suyama, S., Kuwako, K., Imai, T., Murayama, S., Suzuki, N., and Okano, H
- Journal Title
  
  Mol. Brain
  
  Volume: 6 Issue: 1 Pages: 31-31
- DOI
  10.1186/1756-6606-6-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21228003, KAKENHI-PUBLICLY-24111543, KAKENHI-PROJECT-24300122, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24601016, KAKENHI-PROJECT-25430073
[Journal Article] Cellular toxicity induced by the 26-kDa fragment and amyotrophic lateral sclerosis-associated mutant forms of TAR DNA-binding protein 43 in human embryonic stem cell-derived motor neurons.2013
- Author(s)
  Nishimoto Y., Okano HJ, Imai T., Poole AJ., Suzuki N., Keirstead HS and Okano H.
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Issue: 1 Pages: 24-31
- DOI
  10.1002/ncn3.2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24601016
[Journal Article] RNA editing of the Q/R site of GluA2 in cultured cell lines expressing different levels of the RNA editing enzyme ADAR22012
- Author(s)
  Yamashita T, Tadami C, Nishimoto Y, Hideyama T, Kimura D, Suzuki T,Kwak S
- Journal Title
  
  Neurosci Res
  
  Volume: 73 Issue: 1 Pages: 42-48
- DOI
  10.1016/j.neures.2012.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390173, KAKENHI-PROJECT-23790977, KAKENHI-PROJECT-23791002, KAKENHI-PUBLICLY-23110503
[Journal Article] RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI(3) Kinase/Akt Signaling Pathways2012
- Author(s)
  Muto J, Imai T, Ogawa D, Nishimoto Y, Okada Y, Mabuchi Y, Kawase T, Iwanami A, Mischel PS, Saya H, Yoshida K, Matsuzaki Y, Okano H
- Journal Title
  
  PLoS One
  
  Volume: 7(3) Issue: 3 Pages: e33431-e33431
- DOI
  10.1371/journal.pone.0033431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390062, KAKENHI-PUBLICLY-23110516, KAKENHI-PROJECT-23650194, KAKENHI-PROJECT-23689017, KAKENHI-PROJECT-23791002, KAKENHI-PROJECT-23791446, KAKENHI-PROJECT-24500447
[Journal Article] Neurological picture. Neuroaxonal integrity evaluated by MR spectroscopy in a case of CARASIL.2011
- Author(s)
  Nishimoto Y,
- Journal Title
  
  J Neurol Neurosurg Psychiatry.
  
  Volume: 82 Issue: 8 Pages: 860-861
- DOI
  10.1136/jnnp.2010.240051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390174, KAKENHI-PROJECT-23791002
[Journal Article] microRNA-206によるALSモデルマウスの疾患進行抑制と神経筋接合部におけるシナプス再生の促進2011
- Author(s)
  西本祥仁
- Journal Title
  
  MEDICAL BRIEFS IN Brain & Nerve
  
  Volume: 18 Pages: 8-9
- Data Source
  KAKENHI-PROJECT-23791002
[Journal Article] Identification of a Novel Intronic Enhancer Responsible for the Transcriptional Regulation of Musashi1 in Neural Stem/Progenitor Cells2011
- Author(s)
  Kawase S, Imai T, Miyauchi-Hara C, Yaguchi K, Nishimoto Y, Fukami SI, Matsuzaki Y, Miyawaki A, Itohara S, Okano H
- Journal Title
  
  Mol Brain
  
  Volume: 4(1) Issue: 1 Pages: 14-14
- DOI
  10.1186/1756-6606-4-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390062, KAKENHI-PROJECT-23791002
[Journal Article] Ataxin-2グルタミン鎖伸長と神経変性疾患－ALS, PSP発症リスクとの相関性について2011
- Author(s)
  西本祥仁, 伊東大介
- Journal Title
  
  Cognition and Dementia
  
  Volume: 10 Pages: 58-59
- Data Source
  KAKENHI-PROJECT-23791002
[Journal Article] A novel mutation in the HTRA1 gene causes CARASIL without alopecia.2011
- Author(s)
  Nishimoto Y,
- Journal Title
  
  Neurology.
  
  Volume: 76 Issue: 15 Pages: 1353-1355
- DOI
  10.1212/wnl.0b013e318215281d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390174, KAKENHI-PROJECT-23791002
[Journal Article] マイクロRNA-206によるALSモデルマウスの疾患進行抑制と神経筋シナプス再生の促進2011
- Author(s)
  西本祥仁
- Journal Title
  
  MEDICAL BRIEFS IN Brain & Nerve
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21790850
[Journal Article] Headache associated with myasthenia gravis: the impact of mild ocular symptoms.2011
- Author(s)
  Yoshinori Nishimoto, Shigeaki Suzuki, Kimiaki Utsugisawa, Yuriko Nagane, Mamoru Shibata, Toshihiko Shimizu, Norihiro Suzuki.
- Journal Title
  
  Autoimmune Diseases
  
  Volume: 2011 Pages: 840364-840364
- DOI
  10.4061/2011/840364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791002
[Journal Article] 一過性全健忘でのヒト海馬CA1領域の限局性病変は空間ナビゲーション学習を障害する2011
- Author(s)
  西本祥仁, 伊東大介
- Journal Title
  
  MEDICAL BRIEFS IN Brain & Nerve
  
  Volume: 18 Pages: 6-7
- Data Source
  KAKENHI-PROJECT-23791002
[Journal Article] マイクロRNA-206によるALSモデルマウスの疾患進行抑制と神経筋シナプス再生の促進2011
- Author(s)
  西本祥仁
- Journal Title
  
  MEDICAL BRIEFS IN Brain & Nerve 18(2)
  
  Pages: 8-9
- Data Source
  KAKENHI-PROJECT-21790850
[Journal Article] Slow-progressive ataxia with a methionine-to-arginine point mutation in codon 232 in the prion protein gene (PRNP).2011
- Author(s)
  Yoshinori Nishimoto, Daisuke Ito, Shigeaki Suzuki, Toshihiko Shimizu, Tetsuyuki Kitamoto and Norihiro Suzuki.
- Journal Title
  
  Clinical Neurology and Neurosurgery
  
  Volume: 113 Issue: 8 Pages: 696-698
- DOI
  10.1016/j.clineuro.2011.04.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791002, KAKENHI-PROJECT-22249034
[Journal Article] Novel etiological and therapeutic strategies for neurodiseases : RNA editing enzyme abnormality in sporadic amyotrophic lateral sclerosis.2010
- Author(s)
  Hideyama T, Yamashita T, Nishimoto Y, Suzuki T, Kwak S
- Journal Title
  
  Journal of pharmacological sciences
  
  Volume: 113(1) Pages: 9-13
- NAID
  10027744823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790850
[Journal Article] Novel etiological and therapeutic strategies for neurodiseases : RNA editing enzyme abnormality in sporadic amyotrophic lateral sclerosis.2010
- Author(s)
  Hideyama T, Yamashita T, Nishimoto Y, Suzuki T, Kwak S.
- Journal Title
  
  Journal of pharmacological sciences 113(1)
  
  Pages: 9-13
- NAID
  10027744823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790850
[Journal Article] TDP-43タンパク新規アイソフォームの同定と35-kDa封入体特性の検討2010
- Author(s)
  西本祥仁,伊東大介,鈴木則宏
- Journal Title
  
  最新医学 65(7)
  
  Pages: 1579-1587
- Data Source
  KAKENHI-PROJECT-21790850
[Journal Article] TDP-43タンパク新規アイソフォームの同定と35-kDa封入体特性の検討2010
- Author(s)
  西本祥仁, 伊東大介, 鈴木則宏
- Journal Title
  
  最新医学
  
  Volume: 65(7) Pages: 1579-1587
- Data Source
  KAKENHI-PROJECT-21790850
[Journal Article] Characterization of alternative isoforms and inclusionbody of the TAR DNA-binding protein-43.2010
- Author(s)
  Nishimoto Y, Ito D, Yagi T, Nihei Y, Tsunoda Y.Suzuki N.
- Journal Title
  
  Journal of Biological Chemistry 285(1)
  
  Pages: 608-619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790850
[Journal Article] Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.2010
- Author(s)
  Nishimoto Y, Ito D, Yagi T, Nihei Y, Tsunoda Y, Suzuki N.
- Journal Title
  
  Journal of Biological Chemistry 285(1)
  
  Pages: 608-619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] Association between sleep duration and cognitive function in the very old people: A cross-sectional study.2023
- Author(s)
  Ryo Shikimoto、Takashi Sasaki、Yukiko Abe、Yoshinori Nishimoto、Takumi Hirata、Masaru Mimura、Yasumichi Arai
- Organizer
  第12回IAGG-AOR（アジア/オセアニア国際老年学会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] 神経疾患に対する核酸医薬の実用を視野に入れた診療ストラテジー2023
- Author(s)
  西本祥仁
- Organizer
  神経筋疾患Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] Status and physiological significance of circulating adiponectin in the very old and centenarians2023
- Author(s)
  Takashi Sasaki, Yoshinori Nishimoto, Takumi Hirata, Yukiko Abe, Nobuyoshi Hirose, Michiyo Takayama, Toru Takebayashi, Hideyuki Okano, Yasumichi Arai
- Organizer
  The International Centenarian Consortium: ICC 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] tRNA metabolism and motor neuron diseases2023
- Author(s)
  Yoshinori Nishimoto
- Organizer
  The 35th Tokyo RNA Club
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] ニボルマブ投与後に心筋炎を合併したirAE筋炎の1例2023
- Author(s)
  忽滑谷智紀, 徳安大輝, 手塚俊樹, 西本祥仁, 水野里香, 浜本康夫, *鈴木重明, 中原仁
- Organizer
  日本内科学会第685回関東地方会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] To Investigate When and What to Do for Deep Subcortical White Matter Hyperintensity (DSWMH) in a Large Cohort Study2023
- Author(s)
  oshinori Nishimoto, Kyoko Hiyoshi-Arai, Sadanori Higashino, Hidetaka Takeda, Takahiro Amano
- Organizer
  The 75th AAN Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] ニボルマブ投与後に心筋炎を合併したirAE筋炎の1例2023
- Author(s)
  忽滑谷智紀, 徳安大輝, 手塚俊樹, 西本祥仁, 水野里香, 浜本康夫, 鈴木重明, 中原仁
- Organizer
  日本内科学会第685回関東地方会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] ALSの診断と治療アップデート2023
- Author(s)
  西本祥仁
- Organizer
  ALS医療連携セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] Status and physiological significance of circulating adiponectin in the very old and centenarians2023
- Author(s)
  Takashi Sasaki, Yoshinori Nishimoto, Takumi Hirata, Yukiko Abe, Nobuyoshi Hirose, Michiyo Takayama, Toru Takebayashi, Hideyuki Okano, Yasumichi Arai
- Organizer
  第12回IAGG-AOR（アジア/オセアニア国際老年学会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] Investigation into the Difference of Cognitive Decline between the Centenarians and Alzheimer's Disease2023
- Author(s)
  Yoshinori Nishimoto, Takashi Sasaki, Yukiko Abe, Mika Konishi, Daisuke Ito, Shogyoku Bun, Yuri Otaki, Norikazu Hara, Akinori Miyashita, Takeshi Ikeuchi, Yasumichi Arai
- Organizer
  The 75th AAN Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] 超高齢者におけるGrowth differentiation factor-15と頸動脈硬化との関連：The Kawasaki Aging and Wellbeing Project2022
- Author(s)
  新井康通、平田　匠、西本祥仁、阿部由紀子
- Organizer
  第54回日本動脈硬化学会総会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] Impact of Amyloid and tau PET Combination on Changes in Diagnosis and Management2022
- Author(s)
  下濱　祥、手塚俊樹、高畑圭輔、文　鐘玉、田渕　肇、関　守信、百田友紀、三村　悠、西本祥仁、色本　涼、舟木　桂、窪田真人、山本保天、佐野康徳、中原仁、三村將、伊東大介
- Organizer
  第41回日本認知症学会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] Impact of Amyloid and Tau PET Combination on Changes in Diagnosis and Management2022
- Author(s)
  Shimohama S, Tezuka T, Keisuke T, Bun S, Tabuchi H, Seki M, Momota Y, Suzuki N, Morimoto A, Iwabuchi Y, Kubota M, Yamamoto Y, Sano Y, Shikimoto R, Funaki K, Mimura Y, Nishimoto Y, Ueda R, Jinzaki M, Nakahara J, Mimura M, Ito D.
- Organizer
  第41回日本認知症学会学術集会第37回日本老年精神医学会
- Data Source
  KAKENHI-PROJECT-23K21397
[Presentation] 超高齢者における血漿アミロイドβと認知機能：川崎ウェルビーイングプロジェクト2022
- Author(s)
  色本　涼、佐々木貴史、阿部　由紀子、西本　祥仁、平田　匠、三村　將、新井　康通
- Organizer
  第41回日本認知症学会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] 百寿者の認知機能と遺伝学的背景2022
- Author(s)
  新井康通、佐々木貴史、西本祥仁、三村　將、岡野栄之、広瀬信義
- Organizer
  第41回日本認知症学会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] 生体腎移植患者の汎発性帯状疱疹に対してアシクロビル投与中に発症したVZV髄膜炎2022
- Author(s)
  内川理紗、髙宮城冴子、松本薫郎、伊東可寛、川崎洋、徳安大輝、森田伸也、西本祥仁、中村善雄
- Organizer
  第904回日本皮膚科学会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] ACE-IIIを用いた加齢性認知機能低下とアルツハイマー型認知症との鑑別点の考察2021
- Author(s)
  西本祥仁，佐々木貴史，阿部由紀子，江口洋子，色本涼, 三村將，岡野栄之, 新井康通
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] 卵巣癌を背景として発症したN型VGCC抗体を伴う急性精神・高次機能障害に関する臨床的検討2021
- Author(s)
  北川賢、久冨木原健二、窪田真人、西本祥仁、中原仁
- Organizer
  神経免疫学会
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] The gender differences in the centenarians with extreme aging are affected by APOE e4 alleles2021
- Author(s)
  Yoshinori Nishimoto
- Organizer
  第62回日本神経学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07281
[Presentation] 孤発性ALS の運動神経細胞において特異的に出現する核内構造体の同定2013
- Author(s)
  西本祥仁, 鈴木則宏, 岡野栄之
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2013-05-31
- Data Source
  KAKENHI-PROJECT-23791002
[Presentation] Investigation into cellular toxicity induced by TDP-43 expression in human ES cell-derived motor neurons’ poster presentation2012
- Author(s)
  Yoshinori Nishimoto
- Organizer
  The 4th symposium on Brain and Mind Research in the Asia-Pacific (BMAP 2012)
- Place of Presentation
  Keio University, Mita, Tokyo
- Data Source
  KAKENHI-PROJECT-23791002
[Presentation] 'Investigation into cellular toxicity induced by TDP-43 expression in human ES cell-derived motor neurons' poster presentation2012
- Author(s)
  Yoshinori Nishimoto, Hirotaka James Okano, Takao Imai and Hideyuki Okano
- Organizer
  The 4th symposium on Brain and Mind Research in the Asia-Pacific (BMAP 2012)
- Place of Presentation
  Keio University, Mita, Tokyo
- Data Source
  KAKENHI-PROJECT-23791002
[Presentation] ヒト胚性幹細胞由来運動神経細胞での TDP-43 発現による細胞毒性の検討2012
- Author(s)
  西本祥仁, 岡野ジェイムス洋尚, 今井貴雄, 鈴木則宏, 岡野栄之
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-23791002
[Presentation] CARASILのMRI画像2011
- Author(s)
  野崎洋明、福武敏夫、下江豊、平山幹生、柳川宗平、西本祥仁、柴田護、鈴木則宏、西澤正豊、小野寺理
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場 (愛知県)
- Data Source
  KAKENHI-PROJECT-23791002
[Presentation] 禿頭を欠くCARASILにおいて認められた新規HTRA1遺伝子変異に関する分子生物学的考察2011
- Author(s)
  西本祥仁、柴田護、二本松萌、野崎洋明、志賀篤、白田明子、山根清美、小堺有史、高橋一司、西澤正豊、小野寺理、鈴木則宏
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場 (愛知県)
- Data Source
  KAKENHI-PROJECT-23791002
[Presentation] 演題「Investigation into novel functions of the 35-kDa short form of TDP-432010
- Author(s)
  西本祥仁, 伊東大介, 鈴木則宏
- Organizer
  ポスター発表,第1回新潟大学脳研究所共同研究拠点国際シンポジウムBRI International Symposium 2010 Current Understandings and Future Directionsfor ALS
- Place of Presentation
  新潟大学医学部統合脳機能研究センター
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] TDP-43蛋白の新規アイソフォームの同定とStress granuleの形成2010
- Author(s)
  西本祥仁, 伊東大介, 鈴木則宏
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] TDP-43蛋白C末断片の産生機序解明とその生化学的特性の解析2010
- Author(s)
  西本祥仁、伊東大介、鈴木則宏
- Organizer
  こころの健康科学「筋萎縮性側索硬化症・認知症を伴う筋萎縮性側索硬化症・ユビキチン陽性封入体を伴う前頭側頭葉変性症脳・脊髄資源の構築」班会議
- Place of Presentation
  東京都健康長寿医療センター高齢者ブレインバンク
- Year and Date
  2010-01-30
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] Investigation into novel functions of the 35-kDa short form of TDP-43.2010
- Author(s)
  Yoshinori Nishimoto, Daisuke Ito, Norihiro Suzuki
- Organizer
  BRI International Symposium 2010 Current Understandings and Future Directions for ALS
- Place of Presentation
  新潟大学医学部統合脳機能研究センター
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] TDP-43蛋白の新規アイソフォームの同定とStress granuleの形成2010
- Author(s)
  西本祥仁, 伊東大介, 鈴木則宏
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] 演題「TDP-43蛋白C末断片の産生機序解明とその生化学的特性の解析」口演発表2010
- Author(s)
  西本祥仁、伊東大介、鈴木則宏
- Organizer
  こころの健康科学「筋萎縮性側索硬化症・認知症を伴う筋萎縮性側索硬化症・ユビキチン陽性封入体を伴う前頭側頭葉変性症脳・脊髄資源の構築」班会議
- Place of Presentation
  東京都健康長寿医療センター高齢者ブレインバンク
- Year and Date
  2010-01-30
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] 「Characterization of alternative isoforms and inclusion bodies of the TDP-43」口演発表2009
- Author(s)
  西本祥仁, 伊東大介, 八木拓也, 二瓶義廣, 角田佳子, 鈴木則宏
- Organizer
  第10回慶應大学医科歯科大学神経内科合同カンファレンス
- Place of Presentation
  ホテルメトロポリタンエドモント(飯田橋)
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] Characterization of alternative isoforms and inclusion bodies of the TDP-43.2009
- Author(s)
  西本祥仁、伊東大介、八木拓也、二瓶義廣、角田佳子、鈴木則宏
- Organizer
  J-CAN(Japanese Consortium of Age-related Neurodegenerative disorders) 2009
- Place of Presentation
  東京ステーションコンファレンス(サピアタワー6階)
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] Characterization of proteolytic cleavage and inclusions of the TDP-43 protein.2009
- Author(s)
  Yoshinori Nishimoto, Daisuke Ito, Takuya Yagi, Yoshihiro Nihei, Yoshiko Tsunoda, Norihiro Suzuki
- Organizer
  Poster presentation, Society for Neuroscience 2009 (McCormick Place)(Abstr Soc Neurosci 2009 ; 145 : 10)
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] 「Characterization of alternative isoforms and inclusion bodies of the TDP-43」口演発表2009
- Author(s)
  西本祥仁, 伊東大介, 八木拓也, 二瓶義廣, 角田佳子, 鈴木則宏
- Organizer
  J-CAN (Japanese Consortium of Age-related Neurodegenerative disorders)
- Place of Presentation
  東京ステーションコンファレンス(サピアタワー)
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] Characterization of proteolytic cleavage and inclusions of the TDP-43 protein.2009
- Author(s)
  Yoshinori Nishimoto, Daisuke Ito, Takuya Yagi, Yoshihiro Nihei, Yoshiko Tsunoda, Norihiro Suzuki
- Organizer
  Society for Neuroscience 2009
- Place of Presentation
  McCormick Place, Chicago, USA
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] Characterization of alternative isoforms and inclusion bodies of the TDP-43.2009
- Author(s)
  西本祥仁、伊東大介、八木拓也、二瓶義廣、角田佳子、鈴木則宏
- Organizer
  第10回慶應大学医科歯科大学神経内科合同カンファルンス
- Place of Presentation
  ホテルメトロポリタンエドモント(飯田橋)
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-21790850
[Presentation] 孤発性ALSの運動神経細胞において特異的に出現する核内構造体の同定
- Author(s)
  西本祥仁
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-23791002
[Presentation] ヒト胚性幹細胞由来運動神経細胞でのTDP-43発現による細胞毒性の検討
- Author(s)
  西本祥仁
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-23791002

1. IMAI TAKAO (10383712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. KAWAE Satoshi (80468496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 芝田晋介 (70407089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 伊東大介 (80286450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. ARAI Yasumichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 郭伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 松崎有未

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 中川真一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 馬渕洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishimoto Yoshinori 西本 祥仁

NISHIMOTO Yoshinori 西本 祥仁

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Co-Researchers

Investigations of a pathological mechanism on the GC / UG-rich RNA sequences in ALS using genome-edited mice to develop novel therapiesPrincipal Investigator

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Targeting microglia to elucidate the molecular pathogenesis of neurodegenerative diseases and establish therapeutic strategies.

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Establishment of the reporter stem cell lines capable of evaluating the cell influence by radiation.

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Investigation of cellular toxicity induced by LIN28 in amyotrophic lateral sclerosisPrincipal Investigator

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The characterization of TDP-43 aggregation in Amyotrophic Lateral Sclerosis (ALS)Principal Investigator

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[Journal Article] Depressive symptoms and carotid arteriosclerosis in very old people aged 85?years and older: A cross‐sectional study by the Kawasaki Aging and Wellbeing Project2024

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[Journal Article] Impact of Amyloid and Tau PET on Changes in Diagnosis and Patient Management2023

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[Journal Article] Measurement of polydoctoring as a crucial component of fragmentation of care among patients with multimorbidity: Cross‐sectional study in Japan2023

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[Journal Article] Prognostic significance of serum testosterone level in patients with castration‐resistant prostate cancer treated with cabazitaxel2023

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[Journal Article] “Missing-piece” sign with dural arteriovenous fistula at craniocervical junction: A case report2023

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[Journal Article] Status and physiological significance of circulating adiponectin in the very old and centenarians: an observational study2023

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[Journal Article] Association between multimorbidity, self-rated health and life satisfaction among independent, community-dwelling very old persons in Japan: longitudinal cohort analysis from the Kawasaki Ageing and Well-being Project2022

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[Journal Article] NEAT1 lncRNA and amyotrophic lateral sclerosis2021

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[Journal Article] ALDH2 p.E504K Variation and Sex Are Major Factors Associated with Current and Quitting Alcohol Drinking in Japanese Oldest Old2021

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Nishimoto Yoshinori 西本祥仁

NISHIMOTO Yoshinori 西本祥仁