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Nakajima Hidemitsu  中嶋 秀満

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NAKAJIMA Hidemitsu  中嶋 秀満

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Researcher Number 30405360
Other IDs
Affiliation (Current) 2025: 大阪公立大学, 大学院獣医学研究科 , 准教授
Affiliation (based on the past Project Information) *help 2024: 大阪公立大学, 大学院獣医学研究科, 准教授
2015 – 2019: 大阪府立大学, 生命環境科学研究科, 准教授
2012 – 2015: 大阪府立大学, 生命環境科学研究科(系), 准教授
2010 – 2012: 大阪府立大学, 生命環境科学研究科, 准教授
2011: 大阪府立大学, 大学院・生命環境科学研究科, 准教授 … More
2011: 大阪府立大学, 生命環境科学研究科・獣医学専攻, 准教授
2009: 生命環境科学研究科, 助教
2007 – 2009: Osaka Prefecture University, 生命環境科学研究科, 助教 Less
Review Section/Research Field
Principal Investigator
Veterinary medical science / Basic veterinary science/Basic zootechnical science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Veterinary medical science, Animal science, and related fields
Except Principal Investigator
Neurochemistry/Neuropharmacology / Biomedical engineering/Biomaterial science and engineering / Veterinary medical science / Biomedical engineering/Biological material science / Applied veterinary science / Applied pharmacology
Keywords
Principal Investigator
GAPDH / 酸化ストレス / 創薬 / アミロイド / 凝集 / 獣医薬理 / 治療薬 / 阻害剤 / アルツハイマー病 / 脳神経疾患 … More / トランスジェニックマウス / 神経変性疾患 / 薬理 / 難治性疾患(認知症・運動機能障害) / コモンクロスシード仮説 / GAPDH凝集 / 脳アミロイドーシス / アルツハイマー型認知症 / モデル動物 / 不安 / GAPDHカスケード / ネコGAPDH / 老齢ネコ / ゲノム編集 / 海馬神経新生 / 社会性ストレス / 脳内酸化ストレス / GAPDH核移行 / うつ・不安様行動 / 精神疾患 / ストレス / 行動薬理 / 行動実験 / 抗ストレス薬 / 抗不安薬 / 抗うつ薬 / 遺伝子ノックダウン / ストレス性精神疾患 / 核移行 / PARP / ミトコンドリア / 凝集阻害剤 / ペプチドミミック / 脳卒中 / GAPDH / ドミナントネガティブ分子 / 新規治療薬開発 / 疾病予防・制御 / 治療 / アミロイド様繊維 / パーキンソン病 … More
Except Principal Investigator
難水溶性薬剤 / DDS / 脳神経疾患 / SN-38 / 標的指向性 / がん / 輸送蛋白質 / 生体内輸送蛋白質 / レドックッスシグナル / 細胞内情報伝達 / 活性イオウ分子種 / 神経変性 / レドックスシグナル / 活性イオウ分子 / リポカリン蛋白質 / リポカリンタンパク質 / ナノカプセル / 生体内輸送タンパク質 / 薬物送達システム / 癌指向性 / タンパク質ナノカプセル / 神経保護 / GDNF / 神経栄養因子 / グリア細胞 / ポリADPリボース / 獣医学 / シグナル伝達 / 神経科学 / 薬理 / 輸送タンパク質 / ポリグルタミン病 / ボツリヌス毒素 / パーキンソン病 / てんかん / C3酵素 / ボツリヌス菌 / 新規治療薬開発 / 疾病予防・制御 / ターゲッティング / 難水溶性抗がん剤 / がんターゲット / ドラッグデリバリーシステム Less
  • Research Projects

    (12 results)
  • Research Products

    (89 results)
  • Co-Researchers

    (25 People)
  •  Therapeutic strategy in brain amyloidosis based on the GAPDH aggregate common cross-seed hypothesisPrincipal Investigator

    • Principal Investigator
      中嶋 秀満
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Osaka Metropolitan University
  •  Development of a new model of cat GAPDH knock-in Alzheimer's disease mice by the latest genome editing methodPrincipal Investigator

    • Principal Investigator
      Nakajima Hidemitsu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Veterinary medical science, Animal science, and related fields
    • Research Institution
      Osaka Prefecture University
  •  Regulation of redox signaling by reactive sulfur species in nervous system

    • Principal Investigator
      Ihara Hideshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka Prefecture University
  •  Elucidation of the pathogenesis of stress-related psychiatric disorders based on the GAPDH cascade and development of treatment strategiesPrincipal Investigator

    • Principal Investigator
      Nakajima Hidemitsu
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Osaka Prefecture University
  •  A neurotrophic role of extracellular poly (ADP-ribose) in neurological sdisorders

    • Principal Investigator
      Takeuchi Tadayoshi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Veterinary medical science
    • Research Institution
      Osaka Prefecture University
  •  A novel therapeutic target for neurological disoders by inhibition of GAPDH aggregationPrincipal Investigator

    • Principal Investigator
      Nakajima Hidemitsu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Osaka Prefecture University
  •  Development of poorly water-soluble drug encapsulated protein nanocapsule possessing cancer directivity and application to DDS

    • Principal Investigator
      Inui Takashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Osaka Prefecture University
  •  Research for therapeutic application of dominant negative GAPDH molecule on oxidative stress-induced disorderPrincipal Investigator

    • Principal Investigator
      NAKAJIMA Hidemitsu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Osaka Prefecture University
  •  Development of intelligent-type drug delivery system by transporter protein.

    • Principal Investigator
      INUI Takashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
    • Research Field
      Applied pharmacology
    • Research Institution
      Osaka Prefecture University
  •  Preclinical study for the therapeutic application of botulinum neurotoxin to intractable brain disorders.

    • Principal Investigator
      KOZAKI Syunji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      Osaka Prefecture University
  •  Development of drug delivery system using intravital transporter protein.

    • Principal Investigator
      TAKASHI Inui
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Osaka Prefecture University
  •  Role of GAPDH amyloid-like fibrils formation in neurodegenerative diseasesPrincipal Investigator

    • Principal Investigator
      NAKAJIMA Hidemitsu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Osaka Prefecture University

All 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] 解糖系酵素glyceraldehyde-3-phosphate dehydrogenase (GAPDH)の多機能性と酸化ストレス性細胞死における役割2010

    • Author(s)
      中嶋秀満、東泰孝、竹内正吉
    • Total Pages
      12
    • Publisher
      放射線生物研究
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Journal Article] Extracellular poly(ADP-ribose) is a neurotrophic signal that upregulates glial cell line-derived neurotrophic factor (GDNF) levels in vitro and in vivo.2017

    • Author(s)
      Nakajima H, Itakura M, Sato K, Nakamura S, Azuma YT, Takeuchi T.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 484 Issue: 2 Pages: 385-389

    • DOI

      10.1016/j.bbrc.2017.01.129

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05029, KAKENHI-PROJECT-15K14857
  • [Journal Article] Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death.2017

    • Author(s)
      Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, Azuma YT, Kuwamura M, Yamaji R, Takeuchi T.
    • Journal Title

      J. Biol. Chem.

      Volume: 292 Issue: 11 Pages: 4727-4742

    • DOI

      10.1074/jbc.m116.759084

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05029, KAKENHI-PROJECT-15J05838
  • [Journal Article] Active site cysteine-null glyceraldehyde-3-phosphate dehydrogenase (GAPDH) rescues nitric oxide-induced cell death.2016

    • Author(s)
      Kubo T., Nakajima H., Nakatsuji M., Itakura M., Kaneshige A., Azuma Y. T., Inui T., and Takeuchi T.
    • Journal Title

      Nitric Oxide

      Volume: 53 Pages: 13-21

    • DOI

      10.1016/j.niox.2015.12.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25242046, KAKENHI-PROJECT-25450428, KAKENHI-PROJECT-25660231
  • [Journal Article] Glyceraldehyde-3-phosphate Dehydrogenase Aggregates Accelerate Amyloid-β Amyloidogenesis in Alzheimer Disease.2015

    • Author(s)
      Itakura, M., Nakajima, H., Kubo, T., Semi, Y., Kume, S., Higashida, S., Kaneshige, A., Kuwamura, M., Harada, N., Kita, A., Azuma, Y. T., Yamaji, R., Inui, T., Takeuchi, T.
    • Journal Title

      J. Biol. Chem.

      Volume: 290 Issue: 43 Pages: 26072-26087

    • DOI

      10.1074/jbc.m115.669291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25242046, KAKENHI-PROJECT-15J05838, KAKENHI-PROJECT-25450428, KAKENHI-PROJECT-25660231
  • [Journal Article] Glyceraldehyde-3-phosphate dehydrogenase aggregation inhibitor peptide: A potential therapeutic strategy against oxidative stress-induced cell death.2015

    • Author(s)
      Itakura M, Nakajima H, Semi Y, Higashida S, Azuma YT, Takeuchi T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 2015 Issue: 2 Pages: 373-376

    • DOI

      10.1016/j.bbrc.2015.09.150

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25450428
  • [Journal Article] Role of Apoptosis Signal-regulating Kinase 1 (ASK1) as an activator of the GAPDH-Siah1 Stress-Signaling Cascade.2015

    • Author(s)
      Tristan C.A., Ramos A., Shahani N., Emiliani F.E., Nakajima H., Noeh C.C., Kato Y., Takeuchi T., Noguchi T., Kadowaki H., Sedlak T.W., Ishizuka K., Ichijo H., Sawa, A.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 290 Issue: 1 Pages: 56-64

    • DOI

      10.1074/jbc.m114.596205

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25870562, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-25450428
  • [Journal Article] Nuclear-translocated glyceraldehyde-3-phosphate dehydrogenase promotes poly(ADP-ribose) polymerase-1 activation during oxidative/nitrosative stress in stroke.2015

    • Author(s)
      Nakajima H, Kubo T, Ihara H, Hikida T, Danjo T, Nakatsuji M, Shahani N, Itakura M, Ono Y, Azuma Y, Inui T, Kamiya A, Sawa A, Takeuchi T
    • Journal Title

      J. Biol. Chem.

      Volume: VOL. 290 Issue: 23 Pages: 14493-14503

    • DOI

      10.1074/jbc.m114.635607

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23120011, KAKENHI-PROJECT-25242046, KAKENHI-PROJECT-25450428, KAKENHI-PROJECT-25660231, KAKENHI-PROJECT-15H04275
  • [Journal Article] Drug delivery system for poorly water-soluble compounds using lipocalin-type prostaglandin D synthase2012

    • Author(s)
      Fukuhara, A., Nakajima, H., Miyamoto, Y., Inoue, K., Kume, S., Lee, YH., Noda, M., Uchiyama, S., Shimamoto, S., Nishimura, S., Ohkubo, T., Goto, Y., Takeuchi, T., and Inui, T.
    • Journal Title

      J. Control. Release

      Volume: 159巻 Pages: 143-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Journal Article] Drug delivery system for poorly water-soluble compounds using lipocalin-type prostaglandin D synthase2012

    • Author(s)
      Fukuhara, A., Nakajima, H., Miyamoto, Y., Inoue, K., Kume, S., Lee, YH., Noda, M., Uchiyama, S., Shimamoto, S., Nishimura, S., Ohkubo, T., Goto, Y., Takeuchi, T., and Inui, T. (correspondence author)
    • Journal Title

      J. Control. Release

      Volume: 159 巻 Pages: 143-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Journal Article] A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in theadult rat brain.2012

    • Author(s)
      Hidemitsu Nakajima, Takeya Kubo, Yuko Semi, Masanori Itakura, Mitsuru Kuwamura, Takeshi Izawa, Yasu-Taka Azuma and Tadayoshi Takeuchi
    • Journal Title

      J. Biotechnol

      Volume: 157 Pages: 326-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Journal Article] A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain2012

    • Author(s)
      Nakajima H, Kubo T, Semi Y, Itakura M, Kuwamura M, Izawa T, Azuma YT, Takeuchi T
    • Journal Title

      Journal of Biotechnology

      Volume: 152(2) Issue: 2 Pages: 326-333

    • DOI

      10.1016/j.jbiotec.2011.10.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Journal Article] A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain2012

    • Author(s)
      Nakajima, H., Kubo, T., Semi, Y., Itakura, M., Kuwamura, M., Izawa, T., Azuma, YT., Takeuchi, T.
    • Journal Title

      J. Biotech

      Volume: 157 Pages: 326-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21380188
  • [Journal Article] Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death2012

    • Author(s)
      Fukuhara, A., Yamada, M., Fujimori, K., Kusumoto, T., Nakajima, H., and Inui, T.
    • Journal Title

      Biochem. J.

      Volume: 443巻 Pages: 75-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Journal Article] Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death.2012

    • Author(s)
      Fukuhara, A., Yamada, M., Fujimori, K., Kusumoto, T., Nakajima, H., and Inui, T. (correspondence author)
    • Journal Title

      Biochem. J.

      Volume: 443 巻 Pages: 75-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Journal Article] An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehydrogenase augments oxidative stress-induced cell death in SH-SY5Y cells.2009

    • Author(s)
      Hidemitsu Nakajima, 他
    • Journal Title

      Biochem.Biophys.Res.Commun 390巻

      Pages: 1066-1071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Journal Article] An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehyd rogenase augments oxidative stress-induced cell death in SH-SY5Y cells.2009

    • Author(s)
      Hidemitsu Nakajima, 他
    • Journal Title

      Biochem.Biophys.Res.Commun. 390巻

      Pages: 1066-1071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Journal Article] GAPDH aggregate formation participates in oxidative stress-induced cell death.2009

    • Author(s)
      Hidemitsu Nakajima, 他
    • Journal Title

      J.Biol.Chem. 284巻

      Pages: 34331-34341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Journal Article] GAPDH aggregate formation participates in oxidative stress-induced cell death.2009

    • Author(s)
      Nakajima, H., Amano, W., Kubo, T., Fukuhara, A., Ihara, H., Azuma, Y., Tajima, H., Inui, T., Sawa, A., and Takeuchi, T.
    • Journal Title

      J. Biol. Chem.

      Volume: 284 巻 Pages: 34331-34341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Journal Article] GAPDH aggregate formation participates in oxidative stress-induced celldeath.2009

    • Author(s)
      Hidemitau Nakajima, 他
    • Journal Title

      J.Biol.Chem. 284

      Pages: 34331-34341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Journal Article] The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death2007

    • Author(s)
      Nakajima H., Amano A., Fujita A., Fukuhara A., Azuma YT., Hata F., Inui T., Takeuchi T.
    • Journal Title

      J. Biol. Chem. 282(36)

      Pages: 26562-26574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Journal Article] The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death2007

    • Author(s)
      Nakajima, H
    • Journal Title

      J.Biol.Chem 282

      Pages: 26562-26574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Patent] GAPDH凝集阻害剤2015

    • Inventor(s)
      中嶋秀満
    • Industrial Property Rights Holder
      中嶋秀満
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-116140
    • Filing Date
      2015-06-08
    • Data Source
      KAKENHI-PROJECT-25450428
  • [Presentation] Oxidative stress-induced GAPDH nuclear translocation in the hippocampus causes depression behaviors by GR and BDNF downregulation in stressed mice.2019

    • Author(s)
      Shoji M, Kita A, Uedo N, Ozaki Y, Azuma YT, Takeuchi T, and Nakajima H*
    • Organizer
      Internatinal Conference on Alzheimer’s Disease & Dementia2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] A GAPDH nuclear translocation inhibitor (CGP3466B) provides anti-depression/anxiety-like effects in social stressed mice.2019

    • Author(s)
      Uedo N, Nakamura S, Shoji M, Ozaki Y, Azuma YT, Takeuchi T, and Nakajima H*
    • Organizer
      Internatinal Conference on Alzheimer’s Disease & Dementia2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] Contribution of GAPDH nuclear translocation in the hippocampus to depression and anxiety-Like behavior in social stressed mice.2018

    • Author(s)
      1.Nakamura S, Kuwamura M, Azuma YT, Takeuchi T, Hikida T, Nakajima H.
    • Organizer
      The 18th World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] 新規メカニズム:GAPDH核移行阻害 によるストレス性精神疾患治療薬の探索2017

    • Author(s)
      中嶋秀満
    • Organizer
      メディカル ジャパン2017大阪
    • Place of Presentation
      インテックス大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] Blockade of GAPDH nuclear translocation in the hippocampus contributes to anti-depressant-like action in stressed mice.2017

    • Author(s)
      Hidemitsu Nakajima, Sunao Nakamura, Akinori Kita, Chiho Senami, Mitsuru Kuwamura, Takatoshi Hikida, Yasu-Taka Azuma, and Tadayoshi Takeuchi
    • Organizer
      47th annual meeting of the Society for Neuroscience
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] 核移行GAPDHによるストレス性精神疾患発症機序と治療法に関する基盤研究2017

    • Author(s)
      板倉正典、中嶋秀満
    • Organizer
      Bio Medical Forum 2017/第7回シンポジウム「バイオインターフェース先端マテリアルの創生」・第6回バイオメディカルフォーラム
    • Place of Presentation
      あべのメディックス・大阪
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] ストレス性精神疾患モデルにおける海馬GAPDH核移行の病態生理学的意義2017

    • Author(s)
      瀬浪千穂、中嶋秀満、東 泰孝、竹内正吉
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] 多機能性酵素GAPDHのレドックス制御と脳神経疾患-GAPDHを標的とした創薬研究と治療戦略-2017

    • Author(s)
      中嶋秀満
    • Organizer
      第14回レドックス・ライフイノベーションシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] 多機能性酵素GAPDHの活性中心チオール酸化修飾と脳神経疾患:新規GAPDH凝集阻害薬の創製2017

    • Author(s)
      中嶋秀満
    • Organizer
      Bio Medical Forum 2017/第7回シンポジウム「バイオインターフェース先端マテリアルの創生」・第6回バイオメディカルフォーラム
    • Place of Presentation
      あべのメディックス・大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] Pharmacological Strategies to Prevent Injury from Stroke Molecular Factors2016

    • Author(s)
      Itakura M, Kubo T, Kaneshige A, Azuma YT, Hikida T, Takeuchi T, Nakajima H.
    • Organizer
      46th annual meeting of the Society for Neuroscience
    • Place of Presentation
      SanDiego (CA, USA).
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] Glycelaldehyde-3-phosphate dehydrogenase (GAPDH) aggregates contribute to the pathogenesis of Alzheimer’s disease.2016

    • Author(s)
      板倉正典、中嶋秀満、東田周作、瀬見優子、久保岳也、東 泰孝、竹内正吉
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      神奈川県横浜市・パシフィコ横浜会議センター
    • Year and Date
      2016-03-10
    • Data Source
      KAKENHI-PROJECT-25450428
  • [Presentation] 細胞外ポリADPリボース(EC-PAR)のグリア細胞株由来神経栄養因子(GDNF)産生に及ぼす影響2016

    • Author(s)
      佐藤啓志、中嶋秀満、板倉正典、東 泰孝、竹内正吉
    • Organizer
      第129回日本薬理学会近畿部会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-15K14857
  • [Presentation] 細胞外ポリADPリボース(EC-PAR)のグリア細胞株由来神経栄養因子(GDNF)産生機構の解明2016

    • Author(s)
      佐藤啓志、中嶋秀満、板倉正典、東 泰孝、竹内正吉
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      藤沢(日本大学)
    • Data Source
      KAKENHI-PROJECT-15K14857
  • [Presentation] GAPDHを基軸としたストレス性精神疾患の発症機序の解明2016

    • Author(s)
      北 明讓、東 泰孝、中嶋秀満、竹内正吉
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      藤沢・日本大学
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] 多機能性酵素GAPDHの活性中心チオール酸化修飾と脳神経疾患:創薬標的としての可能性2016

    • Author(s)
      中嶋秀満
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台市・東北大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] GAPDH カスケードを基軸としたストレス性精神疾患の発症機序の解明2016

    • Author(s)
      北 明讓、中嶋秀満、東 泰孝、竹内正吉
    • Organizer
      第129回日本薬理学会近畿部会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-16H05029
  • [Presentation] Glyceraldehyde-3-phosphate dehydrogenase aggregation inhibitor: Exploring a drug targeting for Alzheimer’s disease.2015

    • Author(s)
      Kita A, Kubo T, Semi Y, Higashida S, Kaneshige A, Itakura M, Azuma YT, Takeuchi T, Nakajima H.
    • Organizer
      45th annual meeting of the Society for Neuroscience
    • Place of Presentation
      米国イリノイ州シカゴ・McCormick Place
    • Year and Date
      2015-10-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25450428
  • [Presentation] Glyceraldehyde-3-phosphate dehydrogenase regulates c-jun N-terminal kinase activation under oxidative stress conditions.2015

    • Author(s)
      Sato K, Itakura M, Azuma YT, Takeuchi T, Nakajima H.
    • Organizer
      45th annual meeting of the Society for Neuroscience
    • Place of Presentation
      米国イリノイ州シカゴ・McCormick Place
    • Year and Date
      2015-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25450428
  • [Presentation] アルツハイマー病の病態形成にGAPDH凝集体が関与する.2015

    • Author(s)
      板倉正典、中嶋秀満、東田周作、瀬見優子、久保岳也、東 泰孝、竹内正吉
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      青森県十和田市北里大学
    • Year and Date
      2015-09-08
    • Data Source
      KAKENHI-PROJECT-25450428
  • [Presentation] リポカリン型プロスタグランジンD合成酵素による難水溶性抗癌剤SN-38対するドラッグデリバリーシステム2013

    • Author(s)
      井上 遥,河野正樹,北出高志,斎藤茉有,中辻匡俊,中嶋秀満,石橋 宰,乾 隆
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25242046
  • [Presentation] Glyceraldehyde-3-phosphate dehydrogenase act as a seed of alfa-synuclein amyloidogensesis in oxidative stress-induced neurotoxicity both in vitro and in vivo2013

    • Author(s)
      Hidemitsu Nakajima, Takeya Kubo, Ayano Fukuhara, Masanori Itakura, Mitsuru Kuwamura, Yasu-Taka Azuma, Takashi Inui, Tadayoshi Takeuchi
    • Organizer
      The 11thInternational Conference On Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      イタリア、フィレンツェ(ポスター発表
    • Year and Date
      2013-03-08
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] Glyceraldehyde-3-phosphate dehydrogenase aggregates accelerates amyloidogensesis of amyloid-β40 and promotes amyloid-・40-induced cell death2013

    • Author(s)
      Takeya Kubo, Hidemitsu Nakajima, Yuko Semi, Satoshi Kume, Masanori Itakura,Shusaku Higashida, Mitsuru Kuwamura, Yasu-Taka Azuma, Takashi Inui and Tadayoshi Takeuchi
    • Organizer
      The 11thInternational Conference On Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      イタリア、フィレンツェ(ポスター発表)
    • Year and Date
      2013-03-07
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] GAPDH凝集阻害による新規アルツハイマー病治療薬の創製2013

    • Author(s)
      8.東田周作、久保岳也、板倉正典、中嶋秀満、東 泰孝、竹内正吉
    • Organizer
      第123回日本薬理学会近畿部会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25450428
  • [Presentation] GAPDHペプチドのアミロイド凝集抑制効果2012

    • Author(s)
      中嶋秀満
    • Organizer
      Bio tech 2012 アカデミックフォーラム
    • Place of Presentation
      東京ビッグサイト
    • Invited
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] ラットMCAOモデルにおいて、 核移行したGAPDHはPARP-1に直接結合し活性化させる2012

    • Author(s)
      久保岳也、中嶋秀満、Shahani Neelam、東 泰孝、竹内正吉、澤 明
    • Organizer
      第154回日本獣医学会学術集会
    • Place of Presentation
      盛岡(口頭発表)
    • Year and Date
      2012-09-15
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] Amyloid-like fibril of GAPDH enhances aggregation and neurotoxicity of a-synuclein2012

    • Author(s)
      久保岳也、瀬見優子、中嶋秀満、田島久男、東 泰孝、竹内正吉「Amyloid-like fibr
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都(口頭発表)
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] GAPDHペプチドのアミロイド凝集抑制効果2012

    • Author(s)
      中嶋秀満
    • Organizer
      Bio tech 2012 アカデミックフォーラム
    • Place of Presentation
      東京(口頭発表)
    • Year and Date
      2012-04-25
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] AccellTMsiRNA のラット側脳室内投与による脳内遺伝子発現のサイレンシング2011

    • Author(s)
      久保岳也、中嶋秀満、桑村 充、井澤武史、東 泰孝、竹内正吉
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      堺(口頭発表)
    • Year and Date
      2011-09-20
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] リポカリン蛋白質を用いた難水溶性薬剤に対するドラッグ・デリバリー・システムの開発2011

    • Author(s)
      福原彩乃, 中嶋秀満, 宮本優也, 久米慧嗣, 李映昊, 野田勝紀, 内山進, 西村重徳, 大久保忠恭, 後藤祐児, 乾 隆
    • Organizer
      第11 回日本蛋白質科学会年会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪)
    • Year and Date
      2011-06-08
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Presentation] 難水溶性薬物の経口投与におけるリポカリン蛋白質の効果2011

    • Author(s)
      福原彩乃, 久米慧嗣, 河野正樹, 人見麻衣, 李映昊, 後藤祐児, 中嶋秀満, 乾隆
    • Organizer
      第27回日本DDS学会学術集会
    • Place of Presentation
      東京大学本郷キャンパス(東京)
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Presentation] Drug Delivery System for Poorly Water-soluble Compounds Using Lipocalin Protein.2011

    • Author(s)
      Fukuhara, A., Nakajima, H., Miyamoto, Y., Kume, S., Lee, YH., Noda, M., Uchiyama, S., Ohkubo, T., Goto, Y. and Inui, T.
    • Organizer
      The 25th Annual Symposium of The Protein Society
    • Place of Presentation
      Boston Marriott Copley Place (Boston, USA)
    • Year and Date
      2011-07-25
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Presentation] Accell siRNAの単回脳室内投与による脳内の遺伝子サイレンシング効果2011

    • Author(s)
      久保岳也、中嶋秀満、瀬見優子、桑村 充、井澤武史、東 泰孝、竹内正吉
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀(口頭発表)
    • Year and Date
      2011-09-27
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] Accel ITM siRNAのラット側脳室内投与による脳内遺伝子発現のサイレンシング2011

    • Author(s)
      久保岳也、中嶋秀満、桑村充、井澤武史、東泰孝、竹内正吉
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      大阪府立大学(堺市)
    • Year and Date
      2011-09-20
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] GAPDH凝集物はアミロイドβの線維化を促進する2011

    • Author(s)
      瀬見優子、中嶋秀満、久保岳也、板倉正典、東 泰孝、竹内正吉
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀(口頭発表)
    • Year and Date
      2011-09-27
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] 新型siRNAのラット側脳室内単回投与によるin vivo脳内蛋白質ノックダウンの有用性2011

    • Author(s)
      久保岳也、中嶋秀満、桑村 充、井澤武史、東 泰孝、竹内正吉
    • Organizer
      第64回日本薬理学会西南部会
    • Place of Presentation
      福岡(口頭発表)
    • Year and Date
      2011-11-20
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] アミロイドβのアミロイド化と細胞死に対するGAPDHアミロイド様線維の増強効果2011

    • Author(s)
      瀬見優子、中嶋秀満、久保岳也、板倉正典、東 泰孝、竹内正吉
    • Organizer
      第64回日本薬理学会西南部会
    • Place of Presentation
      福岡(口頭発表)
    • Year and Date
      2011-11-20
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] 難水溶性薬物の経口投与におけるリポカリン蛋白質の効果2011

    • Author(s)
      福原彩乃, 久米慧嗣, 河野正樹, 人見麻衣, 李映昊, 後藤祐児, 中嶋秀満, 乾 隆
    • Organizer
      第27回日本DDS 学会学術集会
    • Place of Presentation
      東京大学本郷キャンパス (東京)
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Presentation] Accell siRNAの単回脳室内投与による脳内の遺伝子サイレンシング効果2011

    • Author(s)
      久保岳也、中嶋秀満、瀬見優子、桑村充、井澤武史、東泰孝、竹内正吉
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-21380188
  • [Presentation] GAPDHアミロイド様線維はアミロイドβの凝集を促進する2011

    • Author(s)
      瀬見優子、中嶋秀満、久保岳也、板倉正典、東 泰孝、竹内正吉
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      堺(口頭発表)
    • Year and Date
      2011-09-20
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] 多機能性酵素GAPDHの脳神経疾患における機能的役割と創薬ターゲットとしての可能性2011

    • Author(s)
      中嶋秀満
    • Organizer
      大阪府立大学メディカルバイオフォーラム
    • Place of Presentation
      泉佐野(口頭発表)
    • Year and Date
      2011-01-29
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] リポカリン蛋白質を用いた難水溶性薬剤に対するドラッグ・デリバリー・システムの開発2011

    • Author(s)
      福原彩乃, 中嶋秀満, 宮本優也, 久米慧嗣, 李映昊, 野田勝紀, 内山進, 西村重徳, 大久保忠恭, 後藤祐児, 乾隆
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪)
    • Year and Date
      2011-06-08
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Presentation] Drug Delivery System for Poorly Water-soluble Compounds Using Lipocalin Protein2011

    • Author(s)
      Fukuhara, A., Nakajima, H., Miyamoto, Y., Kume, S., Lee, YH., Noda, M., Uchiyama, S., Ohkubo, T., Goto, Y. and Inui, T.
    • Organizer
      The 25th Annual Symposium of The Protein Society
    • Place of Presentation
      Boston Marriott Copley Place(Boston, USA)
    • Year and Date
      2011-07-25
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Presentation] GAPDHアミロイド様繊維とα-synucleinのクロストークと神経細胞死2010

    • Author(s)
      久保岳也、瀬見優子、中嶋秀満、田島久男、東 泰孝、竹内 正吉
    • Organizer
      第150回日本獣医学会学術集会
    • Place of Presentation
      帯広(口頭発表)
    • Year and Date
      2010-09-16
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] GAPDH凝集特異的ドミナントネガティブ分子による酸化ストレス誘導性神経細胞死の抑制2010

    • Author(s)
      久保岳也、中嶋秀満、東 泰孝、竹内正吉
    • Organizer
      Neuro2010(第33回日本神経科学大会第53回日本神経化学会大会第20回日本神経回路学会大会合同大会)
    • Place of Presentation
      神戸(口頭発表)
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] Drug Delivery System for Poorly Water-soluble Drugs by Lipocalin-type Prostaglandin D Synthase2010

    • Author(s)
      Fukuhara, A., Nakajima, H., Inoue, K., Miyamoto, Y., Shimamoto, S., Nishimura, S., Ohkubo, T., Takeuchi, T., Inui, T.
    • Organizer
      The 24^<th> Annual Symposium of The Protein Society
    • Place of Presentation
      California, USA
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Presentation] 多機能性酵素GAPDHの神経細胞死における機能的役割と創薬標的としての可能性2010

    • Author(s)
      中嶋秀満
    • Organizer
      創薬薬理フォーラム第18回シンポジウム「神経細胞保護」
    • Place of Presentation
      東京(口頭発表)
    • Year and Date
      2010-02-17
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] GAPDH とASK1 の機能的相互作用2010

    • Author(s)
      三崎翔平、中嶋秀満、東 泰孝、一條秀憲、竹内正吉
    • Organizer
      第118回日本薬理学会近畿部会
    • Place of Presentation
      豊中(口頭発表)
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] Drug Delivery System for Poorly Water-soluble Drugs by Lipocalin-type Prostaglandin D Synthase.2010

    • Author(s)
      Fukuhara, A., Nakajima, H., Inoue, K., Miyamoto, Y., Shimamoto, S., Nishimura, S., Ohkubo, T., Takeuchi, T., Inui, T.
    • Organizer
      The 24^<th> Annual Symposium of The Protein Society
    • Place of Presentation
      California, USA
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Presentation] 新規酸化ストレスカスケード:GAPDH-ASK1経路の病態生理学的意義の解明2010

    • Author(s)
      三崎翔平、中嶋秀満、東 泰孝、竹内正吉
    • Organizer
      第150回日本獣医学会学術集会
    • Place of Presentation
      帯広(口頭発表)
    • Year and Date
      2010-09-16
    • Data Source
      KAKENHI-PROJECT-22580339
  • [Presentation] Protective effect of lipocalin-type prostaglandin D synthase/NBQX complex on neuronal cell death induced by cerebral ischemia2009

    • Author(s)
      Fukuhara, A., Nakajima, H., Inoue, K., Miyamoto, Y., Nishimura, S., Yagi, N., Takeuchi, T., Inui, T.
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Presentation] Protective effect of lipocalin-type prostaglandin D synthase on oxidative stress-induced apoptosis in SH-SY5Y cells2009

    • Author(s)
      Fukuhara, A., Yamada, M., Kusumoto, T., Nakajima, H., Nishimura, S., and Inui, T.
    • Organizer
      VIII European Symposium of The Protein Society
    • Place of Presentation
      Zurich, Switzerland
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Presentation] Protective effect of lipocalin-type prostaglandin D synthase on oxidative stress-induced apoptosis in SH-SY5Y cells.2009

    • Author(s)
      Fukuhara, A., Yamada, M., Kusumoto, T. Nakajima, H., Nishimura, S., and Inui, T.
    • Organizer
      VIII European Symposium of The Protein Society
    • Place of Presentation
      Zurich, Switzerland
    • Data Source
      KAKENHI-PROJECT-21200076
  • [Presentation] Protective effect of lipocalin-type prostaglandin D synthase/NBQX complex on neuronal cell death induced by cerebral ischemia2009

    • Author(s)
      Fukuhara, A., Nakajima, H., Inoue, K., Miyamoto, Y., Nishimura, S., Yagi, N., Takeuchi, T., Inui, T.
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Data Source
      KAKENHI-PROJECT-21500428
  • [Presentation] 酸化ストレス誘発性細胞死における核内GAPDHのシグナル伝達経路2008

    • Author(s)
      中嶋 秀満
    • Organizer
      第146回日本獣医学会学術集会
    • Place of Presentation
      宮崎市(口頭発表)
    • Year and Date
      2008-09-24
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] 酸化ストレスによるGAPDHの核内移行とその役割2008

    • Author(s)
      小野葉子、居原秀、中嶋秀満、東泰孝、竹内正吉
    • Organizer
      第114回日本薬理学会近畿部会
    • Place of Presentation
      神戸(口頭発表)
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] Moonlighting Protein GAPDHによる神経細胞死の分子メカニズム解明〜GAPDHによるアミロイド様凝集の発見と創薬への展望〜2008

    • Author(s)
      中嶋 秀満
    • Organizer
      第145回日本獣医学会学術集会
    • Place of Presentation
      相模原市
    • Year and Date
      2008-03-30
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] 酸化ストレス誘発性神経細胞死において、核内GAPDHがPARP-1を活性化する2008

    • Author(s)
      小野葉子、居原秀、中嶋秀満、東泰孝、竹内正吉
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山(ポスター発表)
    • Year and Date
      2008-09-11
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] 酸化ストレス誘発性細胞死における核内GAPDHのシグナル伝達経路2008

    • Author(s)
      中嶋秀満、小野葉子、東泰孝、竹内正吉
    • Organizer
      第146回日本獣医学会学術集会
    • Place of Presentation
      宮崎(口頭発表)
    • Year and Date
      2008-09-24
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] Moolighting Protein GAPDHによる神経細胞死の分子メカニズム解明~GAPDHによるアミロイド様凝集の発見と創薬への展望~2008

    • Author(s)
      中嶋秀満、東泰孝、竹内正吉
    • Organizer
      第145回日本獣医学会学術集会(シンポジウム)
    • Place of Presentation
      相模原(口頭発表)
    • Year and Date
      2008-03-30
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] 酸化ストレス誘発性神経細胞死におけるヒトGAPDH活性中心システインの重要性2008

    • Author(s)
      中嶋秀満、天野渉、東泰孝、竹内正吉
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜(口頭発表)
    • Year and Date
      2008-03-18
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] ヒトグリセロアルデヒド3リン酸脱水素酵素の酸化ストレスによるアミロイド様凝集と神経細胞死2007

    • Author(s)
      天野渉、中嶋秀満、東泰孝、竹内正吉
    • Organizer
      第144回日本獣医学会学術集会
    • Place of Presentation
      江別(口頭発表)
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] 酸化ストレスによるグリセロアルデヒド3リン酸脱水素酵素のアミロイド様凝集には活性中心システイン残基が重要である2007

    • Author(s)
      中嶋秀満、天野渉、東泰孝、竹内正吉
    • Organizer
      第30回日本神経科学大会/第50回日本神経化学会大会/第17回日本神経回路学会大会合同学会
    • Place of Presentation
      横浜(口頭発表)
    • Year and Date
      2007-09-10
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] 酸化ストレスによるグリセロアルデヒド3リン酸脱水素酵素のアミロイド様凝集には活性中心システイン残基が重要である2007

    • Author(s)
      中嶋 秀満
    • Organizer
      第30回日本神経科学大会/第50回日本神経化学会大会/第17回日本神経回路学会大会合同学会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-09-10
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] グリセロアルデヒド3リン酸脱水素酵素のアミロイド様凝集と神経細胞死への関与2007

    • Author(s)
      天野渉、中嶋秀満、東泰孝、竹内正吉
    • Organizer
      第30回日本神経科学大会/第50回日本神経化学会大会/第17回日本神経回路学会大会合同学会
    • Place of Presentation
      横浜(ポスター発表)
    • Year and Date
      2007-09-11
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] 酸化ストレスによるヒトグリセロアルデヒド3リン酸脱水素酵素のアミロイド様凝集と神経細胞死への関与2007

    • Author(s)
      天野渉、中嶋秀満、東泰孝、竹内正吉
    • Organizer
      第111回日本薬理学会近畿部会
    • Place of Presentation
      名古屋(口頭発表)
    • Year and Date
      2007-06-15
    • Data Source
      KAKENHI-PROJECT-19580346
  • [Presentation] Glyceraldehyde-3-phosphate dehydrogenase aggregates acts as a seed of amyloid-β40 amyloidogenesis and enhances the cell death both in vitro and in vivo.

    • Author(s)
      Nakajima H., Kubo T., Itakura M., Kaneshige A., Fukuhara A., Azuma Y., Inui T., Takeuchi T.
    • Organizer
      26th International Conference of Alzheimer's Association International Conference
    • Place of Presentation
      デンマーク / コペンハーゲン
    • Year and Date
      2014-07-12 – 2014-07-17
    • Data Source
      KAKENHI-PROJECT-25242046
  • 1.  INUI Takshi (80352912)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 22 results
  • 2.  KUWAMURA Mitsuru (20244668)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 3.  FUJITA Akikazu (60282232)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  TAKEUCHI Tadayoshi (00171611)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 5.  HIKIDA Takatoshi (70421378)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  KOZAKI Syunji (10109895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MIYAKE Masami (10251175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KATOH Keiko (90252684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  YUBA Eiji (80582296)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ISHIBASHI Osamu (70293214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  KATAOKA Yosuke (40291033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  DOI Hisashi (00421818)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Ihara Hideshi (60254447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  東 泰孝 (50298816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  澤 智裕 (30284756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  鳩谷 晋吾 (40453138)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  秋吉 秀保 (50420740)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  チェンバーズ ジェームズ (00621682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  及川 大輔 (20455330)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  永井 義隆 (60335354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  中山 淳 (60743408)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  WADA Koichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  YAGI Naoto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KIDA Tatsuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KADOWAKI Hisae
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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