TSUNESHIGE 常重アントニオ

… Alternative Names

常重アントニオツネシゲアントニオ

TSUNESHIGE Antonio 常重アントニオ

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Researcher Number	30409346
Other IDs	https://orcid.org/0000-0002-3208-0944
Affiliation (Current)	2025: 法政大学, 生命科学部, 教授
Affiliation (based on the past Project Information) *help	2019: 法政大学, 生命科学部, 教授 2011 – 2015: 法政大学, 生命科学部, 教授 2008 – 2009: 法政大学, 生命科学部, 教授 2007: 法政大学, 工学部, 准教授
Review Section/Research Field	Principal Investigator Biophysics/Chemical physics Except Principal Investigator Emergency medicine / Evolutionary biology
Keywords	Principal Investigator 蛋白低分子間相互作用 / 蛋白質間相互作用 / 接触面 / ヘモグロビン / 蛋白質会合 / アロステリー効果 / Allostery / Chemical modification / Protein interface / Protein interaction … More / iodide / chemical modification / ｐrotein interface / dimer / hemoglobin / protein interface / amphiphilic solutes / allostery … More Except Principal Investigator ヘモグロビン / 再灌流障害 / 人工酸素運搬体 / 内呼吸 / 循環 / 外呼吸 / 臓器虚血 / 抗炎症作用 / アポトーシス / 酸化ストレス / 虚血再灌流障害 / 一酸化炭素 / 酸素 / 再還流障害 / 人工酸素運搬対 / 水素 / シアン中毒 / 一酸化炭素中毒 / 酸素代謝障害 / 虚血 / 進化系統樹 / 逆分子進化 / 祖先型蛋白質 / ミオグロビン / 遺伝子組換え / 祖先型 / 分子設計 / 分子進化 / ヘム蛋白質 Less

Experimental approach to respiratory and circulatory failure using artificial oxygen carriers and their derivatives
- Principal Investigator
  
  KAWAGUCHI Akira
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Emergency medicine
- Research Institution
  Tokai University
Innovative Approaches for Oxygen Metabolism Disorder with Artificial Oxygen Carriers and Related Compounds
- Principal Investigator
  
  KAWAGUCHI Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Emergency medicine
- Research Institution
  Tokai University
Osmotic Effects on an Allosteric Protein With a Single InterfacePrincipal Investigator
- Principal Investigator
  
  TSUNESHIGE Antonio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics/Chemical physics
- Research Institution
  Hosei University
Experimental verification of acquisition of hemoprotein high-order functions by reverse molecular evolution
- Principal Investigator
  
  IMAI Kiyohiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Hosei University

All 2014 2013 2012 2011 2008 2007

All Journal Article Presentation Book

[Book] in Hemoglobin: Recent Developments and Topics2011
- Author(s)
  A. Tsuneshige
- Total Pages
  143
- Publisher
  Global View of Allostery: A Predictable Allosteric Behavior of Hemoglobin Is Dictated By Heterotropic Effecetors
- Data Source
  KAKENHI-PROJECT-23540481
[Book] Fronteras Cientificas en el Siglo XXI (Javier Navarro, Ed., Kosmotropic salts from the Hofmeister series decrease the oxygen affinity of human hemoglobin A)2007
- Author(s)
  A. Tsuneshige, K. Imai, T. Haga
- Publisher
  Editorial Cordillera SAC
- Data Source
  KAKENHI-PROJECT-19570222
[Journal Article] T-quaternary structure of oxy human adult hemoglobin in the presence of two allosteric effectors, L35 and IHP.2011
- Author(s)
  Kanaori K, Tajiri Y, Tsuneshige A, Ishigami I, Ogura T, Tajima K, Neya S, Yonetani T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1807 (10) Pages: 1253-1261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23540481
[Journal Article] A new paramagnetic intermediate formed during the reaction of nitrite with deoxyhemoglobin2011
- Author(s)
  Salgado MT, Ramasamy S, Tsuneshige A, Manoharan PT, Rifkind JM.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 133 (33) Pages: 13010-13022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23540481
[Journal Article] Kosmotropic Salts from the Hofmeister Series Decrease the Oxygen Affinity of Human Hemoglobin A2007
- Author(s)
  Tsuneshige, A.
- Journal Title
  
  Fronteras Cientlficas en el Siglo XXI
  
  Pages: 93-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570222
[Journal Article] Method for Determination of Association and Dissociation Rate Constants of Reversible Bimolecular Reactions by Isothermal Titration Calorimetry2007
- Author(s)
  Tsuneshige, A.
- Journal Title
  
  Anal.Chem 79
  
  Pages: 2972-2978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570222
[Journal Article] Method for Determination of Association and Dissociation Rate Constants of Reversible Bimolecular Reactions by Isothermal Titration Calorimetry2007
- Author(s)
  A. Tsuneshige
- Journal Title
  
  Anal. Chem. 79
  
  Pages: 2972-2978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570222
[Presentation] Insight Into the Origin of Allostery. Stepwise Reconstruction Of An Allosteric Protein From Its Subunits2014
- Author(s)
  Tsuneshige, A. & Tokoro, T
- Organizer
  2014 IUPAB Congress
- Place of Presentation
  Brisbane, Australia, (予定)
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] Functional Modulation in a Typical Allosteric Protein Revisited - Beyond "T" and "R"2014
- Author(s)
  Tsuneshige, A., Sugawara, K. & Kanaori. K
- Organizer
  58th Annual Meeting of the Biophysical Society
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] Functional Modulation in a Typical Allosteric Protein Revisited-Beyond "T" and "R"2014
- Author(s)
  Tsuneshige, A., Sugawara, K. & Kanaori, K.
- Organizer
  The 58th Annual Meeting of the Biophysical Society
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] Application of ORP (Oxidation-Reduction Potential) to Freshness Assesment of Fresh Fishes and Meats2014
- Author(s)
  Kurita, Y., Dosaka, N., Tsuneshige, A.. & Okouchi, S.
- Organizer
  The 58th Annual Meeting of the Biophysical Society
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] Insight Into The Origin of Allostery. Stepwise Reconstruction of an Allosteric Protein From Its Subunits2014
- Author(s)
  Tsuneshige，A. &　Tokoro, T.
- Organizer
  IUPAB 2014 International Biophysics Congress
- Place of Presentation
  Brisbane, Australia
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] Impact of Interfacial Chemical Modifications on the Assembly of an Allosteric Protein. Isothermal Calorimetry and Oxygenation2013
- Author(s)
  Tsuneshige, A. & Sugawara, K
- Organizer
  57th Annual Meeting of the Biophysical Society
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] A NEW NON-CANONICAL CONTROL MECHANISM IN AN ALLOSTERIC PROTEIN -AN INERT INTERFACE COMES TO LIFE2013
- Author(s)
  Tsuneshige, A., Sugawara, K., Tajiri, Y. & Kanaori, K.
- Organizer
  57th Biophysical Society Meeting
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] A New Non-Canonical Control Mechanism In An Allosteric Protein - An Inert Interface Comes to Life2013
- Author(s)
  Sugawara, K. & Tsuneshige, A
- Organizer
  57th Annual Meeting of the Biophysical Society
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] IMPACT OF INTERFACIAL CHEMICAL MODIFICATIONS ON THE ASSEMBLY OF AN ALLOSTERIC PROTEIN - ISOTHERMAL2013
- Author(s)
  Sugawara, K. & Tsuneshige, A.
- Organizer
  57th Biophysical Society Meeting
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] An Overlooked Interface in an Old Allosteric Protein Exerts Superlative Allosteric Control of Its Function. The α1β1 Interface of Human Hemoglobin2012
- Author(s)
  Tsuneshige, A., Sugawara, K., Tajiri, Y. & Kanaori, K.
- Organizer
  XVIIth International Conference on Oxygen Binding and Sensing Proteins
- Place of Presentation
  Parma, Italy
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] Intradimeric But Not Interdimeric Interactions Control the Function of Hemoglobin2012
- Author(s)
  Tsuneshige, A.
- Organizer
  Biophysical Society 56th Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] Intradimeric But Not Interdimeric Interactions Control the Function of Hemoglobin2012
- Author(s)
  Tsuneshige, A., Tajiri, Y., Kanaori, K & Nishihara , H
- Organizer
  56th Annual Meeting of the Biophysical Society
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] R→T-quaternary structure transition of oxy hemoglobin in the presence of heterotropic effectors2011
- Author(s)
  Tajiri, Y., Tsuneshige, A., Yonetani, T. and Kanaori, K.
- Organizer
  50th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  兵庫県立大学姫路書写キャンパス
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] Inconsistency in the Structure-Function Relationship of an Allosteric Protein: What Do We Call T and R?2011
- Author(s)
  Tsuneshige, A., Tajiri, Y., Kanaori, K., Yashiro, Y. and Nishihara, H.
- Organizer
  50th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  兵庫県立大学姫路書写キャンパス
- Data Source
  KAKENHI-PROJECT-23540481
[Presentation] ヘモグロビンの基本アロステリック単位2008
- Author(s)
  常重アントニオ
- Organizer
  兵庫県立大学大学院生命理学研究科グローバルCOEプログラム「ピコバイオロジー:原子レベルの生命科学」グローバルCOE研究集会:ヘモグロビン-この未知なるもの-
- Place of Presentation
  兵庫県立先端科学技術支援センター
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19570222
[Presentation] ヘモグロビンの基本アロステリック単位2008
- Author(s)
  常重アントニオ
- Organizer
  兵庫県立大学大学院生命理学研究科グローバルCOEプログラム「ピコバイオロジー : 原子レベルの生命科学」グローバルCOE研究集会
- Place of Presentation
  兵庫県立先端科学支援センター
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19570222
[Presentation] Divide et impera -lessons learned from a Roman principle observed in the study of hemoglobin2008
- Author(s)
  Tsuneshige, A.
- Organizer
  XVth International Conference on Oxygen Binding and Sensing Proteins
- Place of Presentation
  Aarhus, Denmark
- Data Source
  KAKENHI-PROJECT-19570222
[Presentation] Effect of Kosmotropic and chaotropic solutes on an allosteric protein under non-denaturing conditions2008
- Author(s)
  A. Tsuneshige, Y. Yashiro
- Organizer
  第46回生物物理学会年会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-19570222
[Presentation] Molecular dissection of an allosteric protein by using ionic and non-ionic co-solutes and their impact on its function. a new viewto the hemoglobin system2008
- Author(s)
  Tsuneshige, A.
- Organizer
  43th Biophysical Society Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-19570222
[Presentation] Effect of ionic and non-ionic co-soiutes on the activity of beta-galactosidase2008
- Author(s)
  Tsuneshige, A.
- Organizer
  43th Biophysical Society Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-19570222

1. IMAI Kiyohiro (50028528)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. KAWAGUCHI Akira (30195052)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. INOKUCHI Sadaki (60160008)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIRAI Mikiyasu (70162758)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NEYA Saburo (10156169)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YAMANO Mariko (80192409)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAMAKI Tetsuro (10217177)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OKU Naoto (10167322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAGAI Masako (60019578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HAIDA Munetaka (20208408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KANO Koji (60038031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MURAYAMA Chieko (50307295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ENDO Hitoshi (10550551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 北岸宏亮 (60448090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TSUNESHIGE 常重 アントニオ

常重 アントニオ ツネシゲ アントニオ

TSUNESHIGE Antonio 常重 アントニオ

Research Projects

Research Products

Co-Researchers

Experimental approach to respiratory and circulatory failure using artificial oxygen carriers and their derivatives

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Innovative Approaches for Oxygen Metabolism Disorder with Artificial Oxygen Carriers and Related Compounds

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Osmotic Effects on an Allosteric Protein With a Single InterfacePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental verification of acquisition of hemoprotein high-order functions by reverse molecular evolution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] in Hemoglobin: Recent Developments and Topics2011

Author(s)

Total Pages

Publisher

Data Source

[Book] Fronteras Cientificas en el Siglo XXI (Javier Navarro, Ed., Kosmotropic salts from the Hofmeister series decrease the oxygen affinity of human hemoglobin A)2007

Author(s)

Publisher

Data Source

[Journal Article] T-quaternary structure of oxy human adult hemoglobin in the presence of two allosteric effectors, L35 and IHP.2011

Author(s)

Journal Title

Data Source

[Journal Article] A new paramagnetic intermediate formed during the reaction of nitrite with deoxyhemoglobin2011

Author(s)

Journal Title

Data Source

[Journal Article] Kosmotropic Salts from the Hofmeister Series Decrease the Oxygen Affinity of Human Hemoglobin A2007

Author(s)

Journal Title

Data Source

[Journal Article] Method for Determination of Association and Dissociation Rate Constants of Reversible Bimolecular Reactions by Isothermal Titration Calorimetry2007

Author(s)

Journal Title

Data Source

[Journal Article] Method for Determination of Association and Dissociation Rate Constants of Reversible Bimolecular Reactions by Isothermal Titration Calorimetry2007

Author(s)

Journal Title

Data Source

[Presentation] Insight Into the Origin of Allostery. Stepwise Reconstruction Of An Allosteric Protein From Its Subunits2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Functional Modulation in a Typical Allosteric Protein Revisited - Beyond "T" and "R"2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Functional Modulation in a Typical Allosteric Protein Revisited-Beyond "T" and "R"2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Application of ORP (Oxidation-Reduction Potential) to Freshness Assesment of Fresh Fishes and Meats2014

Author(s)

Organizer

Place of Presentation

Data Source

TSUNESHIGE 常重アントニオ

常重アントニオツネシゲアントニオ

TSUNESHIGE Antonio 常重アントニオ