Higuchi Maiko 樋口麻衣子

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HIGUCHI Maiko 樋口麻衣子

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Researcher Number	30420235
Other IDs
Affiliation (Current)	2025: 立教大学, 理学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 立教大学, 理学部, 准教授 2017 – 2020: 立教大学, 理学部, 助教 2016: 東京大学, 大学院薬学系研究科(薬学部), 特任助教 2015: 東京大学, 薬学研究科(研究院), 助教 2015: 東京大学, 分子細胞生物学研究所, 助教 2007 – 2011: The University of Tokyo, 分子細胞生物学研究所, 助教 2006: 東京大学, 分子細胞生物学研究所, 助手
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Functional biochemistry / Biological pharmacy Except Principal Investigator Chemistry / Science and Engineering
Keywords	Principal Investigator Akt / 細胞運動 / 微小管 / EB2/RP1 / 細胞極性 / 癌悪性化 / 細胞運動性 / 紡錘体 / 細胞周期 / PI3K … More / 微小 / シグナル伝達 / PAK / 浸潤 … More Except Principal Investigator バイテクノロジー / 相同組換え / 人工酵素 / ペプチド / 相同組替え / ゲノム編集 / 遺伝子操作 / 核酸 / バイオテクノロジー / 遺伝子 / ゲノム / セリウム / 遺伝子組換え / ペプチド核酸 / 制限酵素 / DNA Less

Regulation of cell cycle-dependent microtubule dynamics by the Akt1-EB2/RP1 signaling pathwayPrincipal Investigator
- Principal Investigator
  
  樋口麻衣子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Rikkyo University
Regulation of microtubule dynamics by EB2/RP1 microtubule binding proteinPrincipal Investigator
- Principal Investigator
  
  Higuchi Maiko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Rikkyo University
Regulation of cell polarity by proto-oncogene AktPrincipal Investigator
- Principal Investigator
  
  HIGUCHI Maiko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Rikkyo University
  The University of Tokyo
原癌遺伝子Aktによる細胞極性制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  樋口麻衣子
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Creation of genome manipulation technology using super restriction enzyme
- Principal Investigator
  
  KOMIYAMA Makoto
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  University of Tsukuba
  The University of Tokyo
Regulation and function of the proto-oncogene AktPrincipal Investigator
- Principal Investigator
  
  HIGUCHI Maiko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Akt経路のよる癌悪性化メカニズムの解明と創薬への応用Principal Investigator
- Principal Investigator
  
  樋口麻衣子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

All 2022 2020 2018 2017 2016 2015 2011 2009 2008 2007

All Journal Article Presentation Book

[Book] 生体の科学 66(5)2015
- Author(s)
  樋口麻衣子
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K06990
[Journal Article] Maternal stress suppresses cell proliferation in the forebrain of zebrafish larvae2020
- Author(s)
  Higuchi Maiko
- Journal Title
  
  Genes to Cells
  
  Volume: 25 Issue: 5 Pages: 350-357
- DOI
  10.1111/gtc.12761
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06118
[Journal Article] The PDK1-Akt Pathway Regulates Radial Neuronal Migration and Microtubules in the Developing Mouse Neocortex2016
- Author(s)
  Itoh, Y., Higuchi, M., Oishi, K.,Kishi, Y., Okazaki, T., Sakai, H., Miyata, T., Nakajima, K., Gotoh, Y.
- Journal Title
  
  PNAS.
  
  Volume: 113(21) Issue: 21 Pages: 2955-64
- DOI
  10.1073/pnas.1516321113
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05773, KAKENHI-PROJECT-15H02355, KAKENHI-PROJECT-15K06947, KAKENHI-PROJECT-15K06990, KAKENHI-PLANNED-16H06481, KAKENHI-PROJECT-16H02457
[Journal Article] The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.2015
- Author(s)
  Okazaki T., Higuchi M., Takeda K., Iwatsuki-Horimoto K., Kiso M., Miyagishi M., Yanai H., Kato A., Yoneyama M., Fujita T., Taniguchi T., Kawaoka Y., Ichijo H. and Gotoh Y.
- Journal Title
  
  Science Signaling
  
  Volume: 8 Issue: 388 Pages: 1-12
- DOI
  10.1126/scisignal.aab1883
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06990, KAKENHI-PROJECT-24590786, KAKENHI-PLANNED-22123003, KAKENHI-PLANNED-26114009, KAKENHI-PLANNED-24115004, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H02357, KAKENHI-PROJECT-15H02514, KAKENHI-PROJECT-26293016, KAKENHI-PROJECT-15H05773, KAKENHI-PROJECT-15H05787
[Journal Article] スキャフォールド分子PAKによるAktの選択的機能制御2009
- Author(s)
  樋口麻衣子、大西啓介、後藤由季子
- Journal Title
  
  実験医学 27
  
  Pages: 540-544
- Data Source
  KAKENHI-PROJECT-20790059
[Journal Article] Scaffolding function of PAK in the PDK1-Akt pathway.2008
- Author(s)
  Higuchi M., et.al.
- Journal Title
  
  Nature Cell Biology 10(11)
  
  Pages: 1356-1364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790059
[Journal Article] Scaffolding function of PAK in the PDK1-Akt pathway.2008
- Author(s)
  樋口麻衣子、大西啓介、菊池知佳子、後藤由季子
- Journal Title
  
  Nature Cell Biology 10
  
  Pages: 1356-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790059
[Journal Article] JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release.2008
- Author(s)
  森靖典, 樋口麻衣子, 平林祐介, 福田光則, 後藤由季子
- Journal Title
  
  EMBO Journal 27
  
  Pages: 76-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790059
[Presentation] 細胞周期依存的な微小管動態制御におけるEB2/RP1の役割の解析2022
- Author(s)
  佐々木沢子、大西啓介、後藤由季子、樋口麻衣子
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-22K06134
[Presentation] 細胞周期依存的な微小管動態制御におけるEB2/RP1の役割の解析2022
- Author(s)
  佐々木沢子、大西啓介、後藤由季子、樋口麻衣子
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06118
[Presentation] Novel mechanism of regulation of microtubule dynamics by EB2/RP1 microtubule binding protein2018
- Author(s)
  樋口麻衣子、大西啓介、後藤由季子
- Organizer
  日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-18K06118
[Presentation] Novel mechanism of regulation of microtubule dynamics by EB2/RP1 microtubule binding protein2018
- Author(s)
  樋口麻衣子、大西啓介、後藤由季子
- Organizer
  日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-15K06990
[Presentation] 微小管結合分子EB2/RP1による微小管動態制御2017
- Author(s)
  樋口麻衣子、大西啓介、久保田紘史、後藤由季子
- Organizer
  日本細胞生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K06990
[Presentation] 原癌遺伝子Aktによる上皮細胞間接着の制御機構の解明2017
- Author(s)
  西春佳、カン洪月、西川紗織、後藤由季子、樋口麻衣子
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-15K06990
[Presentation] 原癌遺伝子AktによるE-カドヘリンを介した細胞間接着制御メカニズムの解明2015
- Author(s)
  カン洪月、西川沙織、後藤由季子、樋口麻衣子
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06990
[Presentation] Regulation and function of proto-oncogene Akt in cell migration2011
- Author(s)
  樋口麻衣子
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(招待講演)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23770142
[Presentation] Scaffolding function of PAK in the PDK1-Akt pathway2009
- Author(s)
  樋口麻衣子、大西啓介、鬼原里奈、後藤由季子
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Data Source
  KAKENHI-PROJECT-20790059
[Presentation] 原癌遺伝子Aktのアイソフォーム特異的機能制御2009
- Author(s)
  樋口麻衣子、大西啓介、韓英讃、鬼原里奈、西川紗織、後藤由季子
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20790059
[Presentation] 原癌遺伝子Aktのアイソフォーム特異的機能制御2009
- Author(s)
  樋口麻衣子、大西啓介、韓英讃、鬼原里奈、西川紗織、後藤由季子
- Organizer
  第82回日本生化学会大会シンポジウム
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-20790059
[Presentation] スキャフォールド分子PAKによるAktの選択的機能制御2008
- Author(s)
  樋口麻衣子、大西啓介、後藤由季子
- Organizer
  BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-20790059
[Presentation] 原癌遺伝子Aktの活性制御メカニズムの解明2008
- Author(s)
  樋口麻衣子、後藤由季子
- Organizer
  東京大学工学系研究科科学生命工学専攻2008年度第1回談話会
- Place of Presentation
  東京大学先端科学技術研究センター(東京)
- Data Source
  KAKENHI-PROJECT-20790059
[Presentation] スキャフォールド分子PAKによるAktの選択的機能制御2008
- Author(s)
  樋口麻衣子
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20790059
[Presentation] Scaffolding function of PAK in the PDK1-Akt pathway2007
- Author(s)
  Higuchi M.
- Organizer
  FASEB meeting
- Place of Presentation
  Indian Wells
- Data Source
  KAKENHI-PROJECT-18790048
[Presentation] PDK1-Akt経路を制御するPAKのスキャフォールド機能2007
- Author(s)
  樋口麻衣子
- Organizer
  第59回日本細胞生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-18790048

1. KOMIYAMA Makoto (50133096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SUMAOKA Jun (10280934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. XU Yan (40506763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ITO Yasuhiro (50508108)

# of Collaborated Projects: 1 results

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5. SHIGI Narumi (00396780)

# of Collaborated Projects: 1 results

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6. AIBA Yuichiro (10581085)

# of Collaborated Projects: 1 results

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7. 後藤由季子

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# of Collaborated Products: 1 results

Higuchi Maiko 樋口 麻衣子

HIGUCHI Maiko 樋口 麻衣子

Research Projects

Research Products

Co-Researchers

Regulation of cell cycle-dependent microtubule dynamics by the Akt1-EB2/RP1 signaling pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of microtubule dynamics by EB2/RP1 microtubule binding proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of cell polarity by proto-oncogene AktPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

原癌遺伝子Aktによる細胞極性制御メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Creation of genome manipulation technology using super restriction enzyme

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation and function of the proto-oncogene AktPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Akt経路のよる癌悪性化メカニズムの解明と創薬への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 生体の科学 66(5)2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Maternal stress suppresses cell proliferation in the forebrain of zebrafish larvae2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The PDK1-Akt Pathway Regulates Radial Neuronal Migration and Microtubules in the Developing Mouse Neocortex2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] スキャフォールド分子PAKによるAktの選択的機能制御2009

Author(s)

Journal Title

Data Source

[Journal Article] Scaffolding function of PAK in the PDK1-Akt pathway.2008

Author(s)

Journal Title

Data Source

[Journal Article] Scaffolding function of PAK in the PDK1-Akt pathway.2008

Author(s)

Journal Title

Data Source

[Journal Article] JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release.2008

Higuchi Maiko 樋口麻衣子

HIGUCHI Maiko 樋口麻衣子