MINAMIZAKI Tomoko 南崎朋子

Researcher Number	30452593
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2023: 広島大学, 医系科学研究科(歯), 助教 2018: 広島大学, 医歯薬保健学研究科, 助教 2017 – 2018: 広島大学, 医歯薬保健学研究科(歯), 助教 2016: 広島大学, 医歯薬保健学研究院(歯), 助教 2012 – 2015: 広島大学, 医歯薬保健学研究院, 助教 … More 2012: 広島大学, 大学院・医歯薬保健学研究院, 助教 2011: 広島大学, 医歯(薬)学総合研究科, 助教 2010: 広島大学, 医歯薬学総合研究科, 助教 2008 – 2010: Hiroshima University, 大学院・医歯薬学総合研究科, 助教 2007: Hiroshima University, 大学院・医歯薬学総合研究科, 研究員 Less
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Basic Section 57010:Oral biological science-related / Orthodontic/Pediatric dentistry Except Principal Investigator Basic Section 57010:Oral biological science-related / Morphological basic dentistry
Keywords	Principal Investigator 骨代謝 / リン代謝 / 細胞・組織 / 骨転移 / 骨芽細胞 / FGF23 / miRNA / Klotho / 石灰化 / 基質小胞 … More / miR-125b / 骨吸収 / がん細胞 / PTH / 再生医学 / カルシウム代謝 / 低リン血症 / リン酸代謝調節 / 無機リン酸 / 歯の形成 / 骨形成 / シグナル伝達 / 歯学 … More Except Principal Investigator 骨芽細胞 / 次世代シークエンシング / RNAシーケンシング / 血管異所性石灰化 / オミクス / 慢性腎不全 / 血管石灰化 / イノシトール6リン酸 / 血管平滑筋 / 異所性石灰化 / トランスクリプトーム / イノシトールリン酸 / 血管 / 骨 / 慢性腎臓病 / ERK / KLotho / マウス / 歯・骨の石灰化 / 可溶化Klotho(細胞外ドメイン) / 可溶型Klotho / FGF23 / マップキナーゼ(ERK) / 石灰化 / Klotho / GF23 Less

Identification of tissue-specific mechanisms of calcification using a combined analysis of transcriptome and chromatin accessibility
- Principal Investigator
  
  Kohno Shohei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Hiroshima University
miR-125bを導入した基質小胞による癌骨転移治療の検討Principal Investigator
- Principal Investigator
  
  南崎朋子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Hiroshima University
A trial of miRNAs derived from bone matrix as an inhibitor for bone metastasisPrincipal Investigator
- Principal Investigator
  
  Minamizaki Tomoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
The roles of downstream factor(s) of cancer cell-derived Klotho on bone mineralizationPrincipal Investigator
- Principal Investigator
  
  MINAMIZAKI TOMOKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
A basic study of de novo function of PTH in mineral metabolism disordersPrincipal Investigator
- Principal Investigator
  
  MINAMIZAKI Tomoko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
A basic study of Klotho as a local factor of hard tissue reproductionPrincipal Investigator
- Principal Investigator
  
  MINAMIZAKI Tomoko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
A basic study on FGF23 for molecular targeted therapy of bone/tooth diseases
- Principal Investigator
  
  YOSHIKO Yuji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
局所リン酸代謝調節に基づく新規の骨・歯科疾患治療の基礎的研究Principal Investigator
- Principal Investigator
  
  南崎朋子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Hiroshima University

All 2022 2021 2018 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] 2,3-Diphospho-D-glyceric acid inhibits calciprotein particle growth and calcification in MOVAS cells but not in MC3T3-E1 cells2022
- Author(s)
  Kharaghani Davood、Kohno Shohei、Minamizaki Tomoko、Hoshino Tomonori、Yoshiko Yuji
- Journal Title
  
  Colloid and Interface Science Communications
  
  Volume: 50 Pages: 100668-100668
- DOI
  10.1016/j.colcom.2022.100668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09816
[Journal Article] The bioactive acidic serine- and aspartate-rich motif Peptide.2015
- Author(s)
  Minamizaki T, Yoshiko Y.
- Journal Title
  
  Curr Protein Pept Sci.
  
  Volume: 16 Issue: 3 Pages: 196-202
- DOI
  10.2174/1389203716666150206122839
- NAID
  120006879596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462858
[Journal Article] Functional diversity of fibroblast growth factors in bone formation.2015
- Author(s)
  Takei Y, Minamizaki T, Yoshiko Y.
- Journal Title
  
  Int J Endocrinol.
  
  Volume: 2015 Pages: 729352-729352
- DOI
  10.1155/2015/729352
- NAID
  120006824054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462858, KAKENHI-PROJECT-26861548
[Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012
- Author(s)
  Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, KOzai Katsuyuki, Aubin Jane E, Maeda Norihiko
- Journal Title
  
  Prostaglandins Other Lipid Mediat
  
  Volume: 97 Issue: 3-4 Pages: 97-102
- DOI
  10.1016/j.prostaglandins.2012.01.001
- NAID
  120006879597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592701, KAKENHI-PROJECT-23792105
[Journal Article] Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012
- Author(s)
  Yoshioka Hirotaka, Yoshiko Yuji, Minamizaki Tomoko, Suzuki Sayaka, Koma Yoshiro, Nobukiyo Asako, Sotomaru Yusuke, Suzuki Atsushi, Ito Mitsuyasu, Maeda Norihiko
- Journal Title
  
  Calcif Tissue Int
  
  Volume: 89 Pages: 192-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792105
[Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012
- Author(s)
  Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, Kozai Katsuyuki, Jane E Aubin, Maeda Norihiko
- Journal Title
  
  Prostaglandins Other Lipid Mediat
  
  Volume: 97 Pages: 97-102
- NAID
  120006879597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792105
[Journal Article] Incisor Enamel Formation is Impaired in Transgenic Rats Overexpressing the Type III NaPi Transporter Slc20al2011
- Author(s)
  Hirotaka Yoshioka, Yuji Yoshiko, Tomoko Minamizaki, Sayaka Suzuki, Yoshiro Koma, Asako Nobukiyo, Yusuke Sotomaru, Atsushi Suzuki, Mitsuyasu Itoh, Norihiko Maeda
- Journal Title
  
  Calcified Tissue International
  
  Volume: 89 Issue: 3 Pages: 192-202
- DOI
  10.1007/s00223-011-9506-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791768, KAKENHI-PROJECT-23592701, KAKENHI-PROJECT-23792105
[Journal Article] 1・,25-dihydroxy-vitamin D3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro.2010
- Author(s)
  Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, et al.
- Journal Title
  
  J Endocrinol 206(3)
  
  Pages: 279-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] 1α,25-dihydroxyvitamin D_3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro.2010
- Author(s)
  Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, Tanne K, Aubin JE, Maeda N.
- Journal Title
  
  J Endocrinol 206(3)
  
  Pages: 279-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791788
[Journal Article] A subset of osteoblasts expressing high endogenous levels of PPARγ switches fate to adipocytes in the rat calvaria cell culture model.2010
- Author(s)
  Yoshiko Y, Oizumi K, Hasegawa T, Minamizaki T, et al.
- Journal Title
  
  PLoS One 26 5(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] A subset of osteoblasts expressing high endogenous levels of PPARγ switches fate to adipocytes in the rat calvaria cell culture model.2010
- Author(s)
  Yoshiko Y, Oizumi K, Hasegawa T, Minamizaki T, Tanne K, Maeda N, Aubin JE.
- Journal Title
  
  PLoS One 26, 5(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791788
[Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E_2 on bone formation in rat calvaria cell cultures.2009
- Author(s)
  Tomoko Minamizaki
- Journal Title
  
  Bone (掲載決定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890140
[Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.2009
- Author(s)
  Minamizaki T, Yoshiko Y, Kozai K, Aubin JE, Maeda N.
- Journal Title
  
  Bone 44(6)
  
  Pages: 1177-1185
- NAID
  120001924001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791788
[Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.2009
- Author(s)
  Minamizaki T, Yoshiko Y, Kozai K, Aubin JE, Maeda N
- Journal Title
  
  Bone 44(6)
  
  Pages: 1177-1185
- NAID
  120001924001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.2009
- Author(s)
  Tomoko Minamizaki
- Journal Title
  
  Bone (In press)
- NAID
  120001924001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] 低リン血症にみる歯の形成の分子基盤2008
- Author(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 鈴木清香, 前田憲彦
- Journal Title
  
  広島歯誌 36
  
  Pages: 1-12
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] New Insights into the Roles of Fibroblast Growth Factor 23.2008
- Author(s)
  Yoshiko Y, Minamizaki T, Maeda N
- Journal Title
  
  Clinzc Rev Bone Miner Metab 6
  
  Pages: 17-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Patent] リン酸化ペプチド、硬組織および/または異所性石灰化抑制剤、抗体ならびに硬組織および/または異所性石灰化促進剤2011
- Inventor(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 平田伊佐雄, 香西克之, 前田憲彦, 渡邉和晃, 清藤勉
- Industrial Property Rights Holder
  国立大学法人広島大学, 株式会社ラフィーネインターナショナル, 株式会社免疫生物研究所
- Industrial Property Number
  2011-150487
- Filing Date
  2011-07-06
- Data Source
  KAKENHI-PROJECT-23792105
[Patent] 石灰化組織における可溶化Klotho、FGF23およびFGFR複合体形成機構を利用した用途2011
- Inventor(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 前田憲彦, 香西克之, 渡邉和晃
- Industrial Property Rights Holder
  国立大学法人広島大学, 株式会社ラフィーネインターナショナル
- Industrial Property Number
  2011-123853
- Filing Date
  2011-06-01
- Data Source
  KAKENHI-PROJECT-23792105
[Patent] 石灰化組織における可溶化Klotho、FGF23およびFGFR複合体形成機構を利用した用途2010
- Inventor(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 香西克之, 渡邉和晃, 前田憲彦
- Industrial Property Rights Holder
  広島大学,ラフィーネインターナショナル
- Industrial Property Number
  2010-136637
- Filing Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21791788
[Patent] 石灰化組織における可溶化Klotho、FGF23およびFGFR複合体形成機構を利用した用途2010
- Inventor(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 他
- Industrial Property Rights Holder
  広島大学,ラフィーネインターナショナル
- Industrial Property Number
  2010-136637
- Filing Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] ４：Calciprotein particles play a role in bone formation and vascular calcification2021
- Author(s)
  Davood Kharaghani, Eben Bashir Kurniawan, Shohei Kohno, Tomonori Hoshino, Tomoko Minamizaki, Yuji Yoshiko
- Organizer
  6th Joint Scientific Meeting in Dentistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09816
[Presentation] ６：MEPE-derived ASARM, an inhibitor of calciparticle protein formation, suppresses vascular calcification but not bone formation2021
- Author(s)
  Davood Kharaghani, Tomoko Minamizaki, Shohei Kohno, Tomonori Hoshino, Yuji Yoshiko
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09816
[Presentation] MiR-125b stored in bone matrix plays a role in osteoblast-osteoclast communication.2018
- Author(s)
  Tomoko Minamizaki, Yuji Yoshiko
- Organizer
  The 10th Annual Meeting of the Japanese Association for RNAi (JARI) The 5th Annual Meeting of Japanese Society of Extracellular Vesicles (JSEV)
- Data Source
  KAKENHI-PROJECT-16K11443
[Presentation] Nano-CT Analysis of Osteocyte Anomalies in Klotho-deficient Mice.2015
- Author(s)
  Minamizaki T, Sakurai K, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
- Organizer
  The American Society for Bone and Mineral Research 2015 Annual Meeting
- Place of Presentation
  Seattle, USA
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] MEPE-ASARM, a substrate of the neutral endopeptidase PHEX involved in rickets/osteomalacia, acts as an inhibitor of bone formation.2015
- Author(s)
  Sakurai K, Minamizaki T, Hayashi I, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
- Organizer
  6th Hiroshima Conference on Education and Science in Dentistry
- Place of Presentation
  Hiroshima
- Year and Date
  2015-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] MEPE=ASARM, a substrate of Phex, decreases bone volume independently ofserum phosphate levels.2014
- Author(s)
  Sakurai K, Minamizaki T, Fujino Y, Takei Y, Yoshioka H, Okada M, Kozai K, Yoshiko Y
- Organizer
  The American Society for Bone and Mineral Research 2014 Annual Meeting
- Place of Presentation
  Houston, TX, USA
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Imaging mass spectrometry-based molecular histology of bone shows the implication of MEPE-ASARM for the Klotho-deficient phonotype.2013
- Author(s)
  Fujino Y, Minamizaki T, Sakurai K, Irie Y, Yoshioka H, Takei Y, Kozai K, Okada M, Yoshiko Y
- Organizer
  The American Society for Bone and Mineral Research 2013 Annual Meeting
- Place of Presentation
  Baltimore, MD, USA
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Soluble Klotho does not rescue but rather exaggerates skeletal defects in klotho-deficient mice.2013
- Author(s)
  Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Kozai K, Yoshiko Y
- Organizer
  2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Transient but not Constitutive Activation of ERK Is Necessary for the Unique Action of FGF23 in Bone2012
- Author(s)
  Minamizaki Tomoko, Konishi Yukiko, Yoshioka Hirotaka, Kozai Katsuyuki, Yoshiko Yuji
- Organizer
  The American Society for Bone and Mineral Research 2012 Annual Meeting
- Place of Presentation
  Minneapolis, U.S.A.
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] Transient but not Constitutive Activation of ERK Is Necessary for the Unique Action of FGF23 in Bone.2012
- Author(s)
  Tomoko Minamizaki, Yukiko Konishi, Hirotaka Yoshioka, Kozai Kozai, Yuji Yoshiko
- Organizer
  The American Society for Bone and Mineral Research 2012 Annual Meeting
- Place of Presentation
  Minneapolis, USA
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] Phosphate Regulates Fibromodulin Expression Through the ERK Pathway in Ameloblasts2012
- Author(s)
  Yoshioka Hirotaka, Yoshiko Yuji, Irie Yasumasa, Minamizaki Tomoko, Kato Yukio, Sugiyama Toshihiro, Maeda Norihiko
- Organizer
  The 41st Annual Meeting of the American Association for Dental Research
- Place of Presentation
  Tampa, U.S.A
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] 細胞外リン酸は ERK1/2 のシグナルを介してエナメル芽細胞における Fibromodulin 遺伝子の発現を抑制する2011
- Author(s)
  入江泰正,吉岡広陽,吉子裕二,南崎朋子,加藤幸夫,前田憲彦
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  岐阜
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] MEPE-derived phosphorylated ASARM is involved in FGF23/soluble Klotho-dependent hypomineralization2011
- Author(s)
  Konishi Yukiko, Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, Kozai Katsuyuki, Jane E. Aubin, Maeda Norihiko
- Organizer
  The American Society for Bone and Mineral Research 2011 Annual Meeting
- Place of Presentation
  San Diego, U.S.A
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] MEPE-associated phosphorylated ASARM is a potential target to facilitate bone mineralization2011
- Author(s)
  Mohri Maya, Yoshiko Yuji, Minamizaki Tomoko, Yoshioka Hirotaka, Maeda Norihiko
- Organizer
  4th Hiroshima Conference on Education and Science in Dentistry
- Place of Presentation
  Hiroshima
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] 骨の石灰化調節に関わる可溶化型Klotho-FGF23 基軸2011
- Author(s)
  南崎朋子、吉子裕二、吉岡広陽、前田憲彦
- Organizer
  日本解剖学会第66回中国・四国支部学術集会
- Place of Presentation
  徳島
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] FGF シグナルによる石灰化調節:FGF23-Phex 経路を中心として2011
- Author(s)
  南崎朋子,吉子裕二,小西有希子,吉岡広陽,香西克之,前田憲彦
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] MEPE 由来リン酸化 ASARM と Phex は FGF23/可溶型Klotho による石灰化の負の調節系と関連する2011
- Author(s)
  小西有希子,吉子裕二,南崎朋子,吉岡広陽,香西克之,前田憲彦
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] 可溶化型Klothoは骨におけるFGF23の作用発現にリクルートされる2010
- Author(s)
  南崎朋子, 他
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization.2010
- Author(s)
  Minamizaki T, Yoshiko Y, Konishi Y、Yoshioka H, et al.
- Organizer
  The 32nd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] 可溶型Klothoは骨におけるFGF23の作用発現にリクルートされる2010
- Author(s)
  南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization2010
- Author(s)
  Minamizaki T, 他
- Organizer
  The American Society for Bone and Mineral Research 2010 Annual Meeting
- Place of Presentation
  カナダ国トロント市
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] Overexpression of the type III sodium-dependent phosphate transporter Pit1 markedly perturbs enamel formation during tooth development.2010
- Author(s)
  Yoshioka H, Yoshiko Y, Minamizaki T, Nobukiyo A, Sotomaru Y, Suzuki A, Ito M, Maeda N.
- Organizer
  The 32nd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto, Canada
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は歯のエナメル質形成に影響し, 骨・ミネラル代謝異常の発症とともに増悪する2010
- Author(s)
  錦織亜矢, 吉岡広陽, 吉子裕二, 南崎朋子, 他
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 他
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization.2010
- Author(s)
  Minamizaki T, Yoshiko Y, Konishi Y, Yoshioka H, Kozai K, Aubin JE, Maeda N.
- Organizer
  The 32nd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] 可溶化型Klothoは骨におけるFGF23の作用発現にリクルートされる2010
- Author(s)
  南崎朋子, 他
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] Overexpression of the type III sodium-dependent phosphate transporter Pit1 markedly perturbs enamel formation during tooth development.2010
- Author(s)
  Yoshioka H, Yoshiko Y, Minamizaki T, et al.
- Organizer
  The 32nd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] 老化関連タンパクKlothoによる骨の石灰化調節機構2010
- Author(s)
  小西有希子, 吉子裕二, 南崎朋子, 北畠聖子, 吉岡広陽, 香西克之, 前田憲彦
- Organizer
  第43回広島大学歯学会総会
- Place of Presentation
  広島
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization2010
- Author(s)
  Minamizaki T, 他
- Organizer
  The American Society for Bone and Mineral Research 2010 Annual Meeting
- Place of Presentation
  カナダ国トロント市
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] 老化関連タンパクKlothoによる骨の石灰化調節機構2010
- Author(s)
  小西有希子, 吉子裕二, 南崎朋子, 吉岡広陽, 他
- Organizer
  第43回広島大学歯学会総会
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は歯のエナメル質形成に影響し,骨・ミネラル代謝異常の発症とともに増悪する2010
- Author(s)
  錦織亜矢, 吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全をきたす2009
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] A Parathyroid Hormone-la, 25-dihydroxyvitamin D_3 FGF23 Loop Regulating Bone Mineralization in Cultured Rat Calvaria Osteoblasts.2009
- Author(s)
  南崎朋子
- Organizer
  The 31st Annual Meeting for American Bone and Mineral Research
- Place of Presentation
  デンバー(アメリカ)
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] PTHと活性型ビタミンD3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し、基質石灰化を調節する2009
- Author(s)
  南崎朋子
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の石灰化不全を来す2009
- Author(s)
  小間義朗, 吉岡広陽, 吉子裕二, 南崎朋子, 他
- Organizer
  第42回広島大学歯学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全を来す2009
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] A Parathyroid Hormone-1α, 25-dihydroxy -vitamin D_3-FGF23 Loop Regulating Bone Mineralization in Cultured Rat Calvaria Osteoblasts.2009
- Author(s)
  Minamizaki T, Yoshiko Y, Yoshioka H, Aubin JE, Maeda N.
- Organizer
  The 31st Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Denver, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全をきたす2009
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] PTHと活性型ビタミンD_3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し,基質石灰化を調節する2009
- Author(s)
  南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] A parathyroid hormone-1α,25-dihydroxyvitamin D_3-FGF23 loop regulating bone mineralization in cultured rat calvaria osteoblasts2009
- Author(s)
  南崎朋子, et al.
- Organizer
  31th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Denver, Colorado, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] PTHと活性型ビタミンD_3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し,基質石灰化を調節する2009
- Author(s)
  南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の石灰化不全を来す2009
- Author(s)
  小間義朗, 吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
- Organizer
  第42回広島大学歯学会総会
- Place of Presentation
  広島
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] A Parathyroid Hormone-1α,25-dihydroxy-vitamin D_3-FGF23 Loop Regulating Bone Mineralization in Cultured Rat Calvaria Osteoblasts.2009
- Author(s)
  Minamizaki T, Yoshiko Y, Yoshioka H, Aubin JE, Maeda N
- Organizer
  The 31st Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Denver, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全を来す2009
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] PTHと活性型ビタミンD3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し、基質石灰化を調節する2009
- Author(s)
  南崎朋子, 他
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] FG23 and FGF2 share a common but also have distinct signaling path ways for negative regulation of bone nodule mineralization in cultured osteoblasts.2008
- Author(s)
  Tomoko Minamizaki
- Organizer
  30th Annual Meeting of the America Society for Bone and Mineral Research
- Place of Presentation
  Montreal, Canada
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] FGF23 and FGF2 share a common but also have distinct signaling pathways for negative regulation of bone nodule mineralization in cultured osteoblasts.2008
- Author(s)
  Minamizaki T, Yoshiko Y, Suzuki S, et al.
- Organizer
  The 30th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Montreal
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] FGF23 and FGF2 Share a Common but also Have Distinct Signaling Pathways for Negative Regulation of Bone Nodule Mineralization in Cultured Osteoblasts.2008
- Author(s)
  Tomoko Minamizaki
- Organizer
  The 30th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  モントリオール, カナダ
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19890140
[Presentation] 1,25(OH)_2D_3、PTHおよびKlothoはFGF23の基質石灰化抑制作用を直接調節する2008
- Author(s)
  南崎朋子, 吉子裕二, 前田憲彦
- Organizer
  第50回歯科基礎医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] 1, 25(OH)_2D_3、PTHおよびklothoはFGF23の基質石灰化抑制作用を直接調節する2008
- Author(s)
  南崎朋子
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-19890140
[Presentation] 1.25(OH)2D3 inhibits bone nodule mineralization through the FGF23-mediating ERK pathway in rat calvaria osteoblast cultures.2007
- Author(s)
  Minamizaki, T
- Organizer
  29th Annual Meeting of the American Mineral Society for Bone and Mineral Research
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-19890140
[Presentation] 骨基質タンパクMEPE-由来ASARMは血中リン濃度非依存的に骨量を減少させる
- Author(s)
  櫻井薫、南崎朋子、川本真貴子、藤野陽子、竹井悠一郎、吉岡広陽、岡田貢、香西克之、吉子裕二
- Organizer
  日本解剖学会第69回中国・四国支部学術集会
- Place of Presentation
  広島
- Year and Date
  2014-10-25 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Phexの基質MEPE-ASARMは血中リン濃度非依存的に骨量を減少させる
- Author(s)
  櫻井薫、南崎朋子、吉岡広陽、竹井悠一郎、香西克之、吉子裕二
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] MEPE-ASARM, a substrate of Phex, decreases bone volume independently of serum phosphate levels
- Author(s)
  Sakurai K, Minamizaki T, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
- Organizer
  The American Society for Bone and Mineral Research 2014 Annual Meeting
- Place of Presentation
  Houston（USA）
- Year and Date
  2014-09-12 – 2014-09-15
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Klotho欠損マウス腎臓のイメージング質量分析
- Author(s)
  藤野陽子、南崎朋子、宮脇聡子、川上朝子、宮地孝明、櫻井薫、竹井悠一郎、吉岡広陽、香西克之、岡田貢、吉子裕二
- Organizer
  日本解剖学会第69回中国・四国支部学術集会
- Place of Presentation
  広島
- Year and Date
  2014-10-25 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25462858

1. YOSHIKO Yuji (20263709)

# of Collaborated Projects: 6 results

# of Collaborated Products: 44 results
2. YOSHIOKA Hirotaka (50523411)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
3. KOZAI Katsuyuki (10178212)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
4. FUTAMURA MANABU (10415515)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. UCHIDA Soshi (60330990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Kohno Shohei (00868391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 新飯田俊平 (10137630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Ahmed Faisal

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Sarmin Nushrat

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Zaurasari Mentari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MINAMIZAKI Tomoko 南崎 朋子

Research Projects

Research Products

Co-Researchers

Identification of tissue-specific mechanisms of calcification using a combined analysis of transcriptome and chromatin accessibility

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miR-125bを導入した基質小胞による癌骨転移治療の検討Principal Investigator

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Review Section

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A trial of miRNAs derived from bone matrix as an inhibitor for bone metastasisPrincipal Investigator

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The roles of downstream factor(s) of cancer cell-derived Klotho on bone mineralizationPrincipal Investigator

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A basic study of de novo function of PTH in mineral metabolism disordersPrincipal Investigator

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A basic study of Klotho as a local factor of hard tissue reproductionPrincipal Investigator

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A basic study on FGF23 for molecular targeted therapy of bone/tooth diseases

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局所リン酸代謝調節に基づく新規の骨・歯科疾患治療の基礎的研究Principal Investigator

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[Journal Article] 2,3-Diphospho-D-glyceric acid inhibits calciprotein particle growth and calcification in MOVAS cells but not in MC3T3-E1 cells2022

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DOI

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[Journal Article] The bioactive acidic serine- and aspartate-rich motif Peptide.2015

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DOI

NAID

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[Journal Article] Functional diversity of fibroblast growth factors in bone formation.2015

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DOI

NAID

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[Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012

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NAID

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[Journal Article] Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012

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[Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012

MINAMIZAKI Tomoko 南崎朋子