Kusumoto Sojiro 楠本壮二郎

… Alternative Names

楠本壮二郎クスモトソウジロウ

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Researcher Number	30465091
Other IDs
Affiliation (Current)	2025: 昭和大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2018: 昭和大学, 医学部, 助教
Review Section/Research Field	Except Principal Investigator Respiratory organ internal medicine
Keywords	Except Principal Investigator 慢性閉塞性肺疾患 / COPD / 発癌 / TNF / EGFR / 腫瘍壊死因子 / 上皮成長因子受容体 / 肺癌

Investigate the role of TNF and EGFR in the onset and progression of lung cancer complicated with COPD
- Principal Investigator
  
  Yamaoka Toshimitsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Showa University

All 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Receptor Tyrosine Kinase-Targeted Cancer Therapy2018
- Author(s)
  Yamaoka Toshimitsu、Kusumoto Sojiro、Ando Koichi、Ohba Motoi、Ohmori Tohru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 11 Pages: 3491-3491
- DOI
  10.3390/ijms19113491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09590, KAKENHI-PROJECT-17K07226
[Journal Article] KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR2018
- Author(s)
  Nakatani Kaori、Yamaoka Toshimitsu、Ohba Motoi、Fujita Ken-Ichi、Arata Satoru、Kusumoto Sojiro、Taki-Takemoto Iori、Kamei Daisuke、Iwai Shinichi、Tsurutani Junji、Ohmori Tohru
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 18 Issue: 1 Pages: 112-126
- DOI
  10.1158/1535-7163.mct-18-0591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08413, KAKENHI-PROJECT-16K09590, KAKENHI-PROJECT-17K07226
[Journal Article] Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation.2017
- Author(s)
  Yamaoka T, Ohmori T, Ohba M, Arata S, Murata Y, Kusumoto S, Ando K, Ishida H, Ohnishi T, Sasaki Y.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 7 Pages: 915-928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09590
[Journal Article] The acquired resistant mechanisms for sequential treatment of EGFR-TKI to Met-TKI/EGFR-TKI in a Met amplified EGFR-TKI resistant lung adenocarcinoma cells, harboring EGFR activating mutation.2016
- Author(s)
  64.Yamaoka T., Ohmori T., Ohba M., Arata S., Kishino Y., Murata Y., Kusumoto S., Ishida H., Shirai T., Hirose T., Ohnishi T., and Sasaki Y.
- Journal Title
  
  Mol. Cancer Ther.
  
  Volume: 15 Issue: 12 Pages: 3040-3054
- DOI
  10.1158/1535-7163.mct-16-0313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460153, KAKENHI-PROJECT-16K09590
[Presentation] KRAS amplification mediates resistance to osimertinib in acquired afatinib-resistant NSCLC harboring exon 19 deletion/T790M in EGFR2019
- Author(s)
  Toshimitsu Yamaoka, Motoi Ohba, Yasunari Kishino, Sojiro Kusumoto, Junji Tsurutani, Tohru Ohmori
- Organizer
  AACR 110th Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] GFR遺伝子変異陽性(exon19del/T790M)肺腺癌細胞株におけるオシメルチニブ獲得耐性機序2019
- Author(s)
  山岡利光, 岸野康成, 楠本壮二郎, 鶴谷純司, 相良博典, 大森亨
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] T790M-EGFRによりアファチニブ耐性をきたした肺腺癌細胞株におけるロシレチニブ耐性機序の検討2018
- Author(s)
  山岡利光,楠本壮二郎,安藤浩一,石田博雄,大西司,相良博典,大森亨
- Organizer
  第59回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] EGFR-Mutationを伴う肺腺癌細胞株におけるEGFR-TKIとMET-TKIへの獲得耐性機序2017
- Author(s)
  山岡利光　大森亨　大場基　村田泰規　大木康成　楠本壮二郎　大西司　相良博典
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] Mechanism underlying acquisition of dual resistance to EGFR and MET inhibitors by EGFR-mutant lung adenocarcinoma cells2016
- Author(s)
  Yamaoka T, Ohmori T, Ohba M, Kishino Y, Murata Y, Kusumoto S, Ishida H, Ohnishi T, Sasaki Y.
- Organizer
  AACR
- Place of Presentation
  ニューオリンズ・米国
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] Mechanism underlying acquisition of dual resistance to EGFR and MET inhibitors by EGFR-mutant lung adenocarcinoma cells2016
- Author(s)
  山岡利光, 大森亨, 大場基, 村田泰規, 楠本壮二郎, 石田博雄, 佐々木康綱
- Organizer
  臨床腫瘍学会
- Place of Presentation
  神戸
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] EGFR-Mutationを伴う肺腺癌細胞株におけるEGFR-TKIとMET-TKIへの獲得耐性機序2016
- Author(s)
  山岡利光, 大森亨, 大場基, 村田泰規, 楠本壮二郎, 石田博雄, 佐々木康綱
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K09590

1. Yamaoka Toshimitsu (40384359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. 大森亨 (10276529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. 荒田悟 (20159502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 佐々木康綱 (20235279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 本間まゆみ (20527171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中嶌賢尚 (90365768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAMEI Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 大場基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kusumoto Sojiro 楠本 壮二郎

楠本 壮二郎 クスモト ソウジロウ

Research Projects

Research Products

Co-Researchers

Investigate the role of TNF and EGFR in the onset and progression of lung cancer complicated with COPD

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Receptor Tyrosine Kinase-Targeted Cancer Therapy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation.2017

Author(s)

Journal Title

Data Source

[Journal Article] The acquired resistant mechanisms for sequential treatment of EGFR-TKI to Met-TKI/EGFR-TKI in a Met amplified EGFR-TKI resistant lung adenocarcinoma cells, harboring EGFR activating mutation.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] KRAS amplification mediates resistance to osimertinib in acquired afatinib-resistant NSCLC harboring exon 19 deletion/T790M in EGFR2019

Author(s)

Organizer

Data Source

[Presentation] GFR遺伝子変異陽性(exon19del/T790M)肺腺癌細胞株におけるオシメルチニブ獲得耐性機序2019

Author(s)

Organizer

Data Source

[Presentation] T790M-EGFRにより アファチニブ耐性をきたした肺腺癌細胞株におけるロシレチニブ耐性機序の検討2018

Author(s)

Organizer

Data Source

[Presentation] EGFR-Mutationを伴う肺腺癌細胞株におけるEGFR-TKIとMET-TKIへの獲得耐性機序2017

Author(s)

Organizer

Data Source

[Presentation] Mechanism underlying acquisition of dual resistance to EGFR and MET inhibitors by EGFR-mutant lung adenocarcinoma cells2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Mechanism underlying acquisition of dual resistance to EGFR and MET inhibitors by EGFR-mutant lung adenocarcinoma cells2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] EGFR-Mutationを伴う肺腺癌細胞株におけるEGFR-TKIとMET-TKIへの獲得耐性機序2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Kusumoto Sojiro 楠本壮二郎

楠本壮二郎クスモトソウジロウ

[Presentation] T790M-EGFRによりアファチニブ耐性をきたした肺腺癌細胞株におけるロシレチニブ耐性機序の検討2018