Sugeno Naoto 菅野直人

… Alternative Names

SUGENO Naoto 菅野直人

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Researcher Number	30509550
Other IDs
Affiliation (Current)	2025: 東北大学, 大学病院, 講師 2025: 東北大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 東北大学, 医学系研究科, 助教 2016 – 2020: 東北大学, 大学病院, 助教 2011 – 2013: 東北大学, 大学病院, 助教 2012: 東北大学, 病院, 助教 2009 – 2010: Tohoku University, 病院, 医員
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology
Keywords	Principal Investigator alpha-synuclein / αシヌクレイン / パーキンソン病 / ヒストン修飾 / αーシヌクレイン / エピジェネティクス / タンパク質 / 脳・神経 / epigenetics / α-シヌクレイン … More / バイオインフォマティクス / クロマチン免疫沈降 / 免疫沈降 / 神経分化 / 小胞輸送 / Nedd4 / ESCRT / カテプシン / グルコセレブロシダーゼ … More Except Principal Investigator シヌクレイノパチー / 多系統萎縮症 / 異常蛋白伝播 / コンディショナルノックアウトマウス / 異常タンパク凝集 / ESCRT / 小胞輸送 / プリオン仮説 / 神経変性疾患 / 神経変性 / アクチン / αシヌクレイン / DNAJC13 / メンブレントラフィック / ショウジョウバエモデル / アルファシヌクレイン / カテプシンD / エンドソーム / レトロマー / VPS35 / PARK17 / パーキンソン病 / シヌクレイン / グリア細胞質封入体 / レビー小体 / 分子イメージング Less

Exploring the role of alpha-synuclein in epigenetic regulation by histone remodeling factor, WDR5Principal Investigator
- Principal Investigator
  
  菅野直人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tohoku University
α-シヌクレインを介したOPRM1遺伝子の転写調節機構の解明Principal Investigator
- Principal Investigator
  
  菅野直人
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tohoku University
Histone modification induced by alpha-synucleinPrincipal Investigator
- Principal Investigator
  
  Sugeno Naoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Zeroing in on aberrant membrane trafficking in molecular pathogenesis of Parkinson's disease
- Principal Investigator
  
  Hasegawa Takafumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
内在化αシヌクレインにおけるESCRTを中心とした小胞輸送に関する研究Principal Investigator
- Principal Investigator
  
  菅野直人
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Early diagnosis and treatment of Parkinson disease dementia
- Principal Investigator
  
  TAKEDA ATSUSHI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Department of Clinical Research, National Hospital Organization Sendai Nishitaga National Hospital
  Tohoku University
Glucocerebrosidase mutation accelerates alpha-synuclein cytotoxityPrincipal Investigator
- Principal Investigator
  
  SUGENO Naoto
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Cytotoxic effect induced by phosphorylated alpha-synuclein and dopaminePrincipal Investigator
- Principal Investigator
  
  SUGENO Naoto
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University

[Book] 運動失調のみかた,考えかた　III-8 プリオン仮説2017
- Author(s)
  菅野　直人、長谷川　隆文
- Total Pages
  358
- Publisher
  中外医学社
- ISBN
  9784498228900
- Data Source
  KAKENHI-PROJECT-17K09745
[Journal Article] Alpha‐synuclein promotes PRMT5‐mediated H4R3me2s histone methylation by interacting with the BAF complex2023
- Author(s)
  Nakamura Takaaki、Sugeno Naoto、Hasegawa Takafumi、Ikeda Kensho、Yoshida Shun、Ishiyama Shun、Sato Kazuki、Takeda Atsushi、Aoki Masashi
- Journal Title
  
  The FEBS Journal
  
  Volume: 291 Issue: 9 Pages: 1892-1908
- DOI
  10.1111/febs.17037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-23K06823, KAKENHI-PROJECT-20K07896
[Journal Article] Detection of Modified Histones from Oral Mucosa of a Patient with DYT-KMT2B Dystonia2023
- Author(s)
  Sugeno Naoto、Hasegawa Takafumi、Haginoya Kazuhiro、Kubota Takafumi、Ikeda Kensuke、Nakamura Takaaki、Ishiyama Shun、Sato Kazuki、Yoshida Shun、Koshimizu Eriko、Uematsu Mitsugu、Miyatake Satoko、Matsumoto Naomichi、Aoki Masashi
- Journal Title
  
  Molecular Syndromology
  
  Volume: 14 Issue: 6 Pages: 461-468
- DOI
  10.1159/000530625
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-23K06823, KAKENHI-PROJECT-20K07896, KAKENHI-PROJECT-23K27520
[Journal Article] Sortilin acts as an endocytic receptor for α‐synuclein fibril2023
- Author(s)
  Ishiyama Shun、Hasegawa Takafumi、Sugeno Naoto、Kobayashi Junpei、Yoshida Shun、Miki Yasuo、Wakabayashi Koichi、Fukuda Mitsunori、Kawata Yasushi、Nakamura Takaaki、Sato Kazuki、Ezura Michinori、Kikuchi Akio、Takeda Atsushi、Aoki Masashi
- Journal Title
  
  The FASEB Journal
  
  Volume: 37 Issue: 7
- DOI
  10.1096/fj.202201605rr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-20K07879, KAKENHI-PROJECT-23K06823, KAKENHI-PROJECT-23K06947, KAKENHI-PROJECT-20K07896, KAKENHI-PROJECT-21K07452, KAKENHI-PROJECT-23K24209
[Journal Article] Unraveling the Complex Interplay between Alpha-Synuclein and Epigenetic Modification2023
- Author(s)
  Sugeno Naoto、Hasegawa Takafumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 7 Pages: 6645-6645
- DOI
  10.3390/ijms24076645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-23K06823
[Journal Article] High prevalence of serum anti-NH2-terminal of α-enolase antibodies in patients with multiple system atrophy and corticobasal syndrome2021
- Author(s)
  Kikuchi A, Yoneda M, Hasegawa T, Matsunaga A, Ikawa M, Nakamura T, Ezura M, Baba T, Sugeno N, Ishiyama S, Nakamoto Y, Takeda A, Aoki M
- Journal Title
  
  J Neurol
  
  Volume: 268 Issue: 11 Pages: 4291-4295
- DOI
  10.1007/s00415-021-10553-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-20K07879, KAKENHI-PROJECT-20K07896
[Journal Article] 18F-THK5351 PET imaging in neurodegenerative tauopathies2021
- Author(s)
  Ezura M, Kikuchi A, Okamura N, Ishiki A, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Yoshida S, Kobayashi J, Kobayashi M, Tano O, Ishiyama S, Nakamura T, Nakashima I, Mugikura S, Iwata R, Taki Y, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
- Journal Title
  
  Front Aging Neurosci
  
  Volume: 13 Pages: 761010-761010
- DOI
  10.3389/fnagi.2021.761010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-20K07830, KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-20K07879, KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-21K19320, KAKENHI-PROJECT-18K15357, KAKENHI-PROJECT-19KK0212
[Journal Article] Case Report: Guitarist’s cramp as the initial manifestation of dopa-responsive dystonia with a novel heterozygous GCH1 mutation2021
- Author(s)
  Hasegawa T, Hosaka T, Harada R, Kawahata I, Hoshino K, Sugeno N, Kikuchi A, Aoki M
- Journal Title
  
  F1000 Research
  
  Volume: 10 Pages: 361-361
- DOI
  10.12688/f1000research.51433.1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-20K07879
[Journal Article] Clinical characterization of patients with leucine-rich repeat kinase 2 genetic variants in Japan2020
- Author(s)
  Li Y、Ikeda A、Yoshino H、Oyama G、Kitani M、Daida K、Hayashida A、Ogaki K、Yoshida K、Kimura T、Nakayama Y、Ito H、Sugeno N、Aoki M、Miyajima H、Kimura K、Ueda N、Watanabe M、Urabe T、Takanashi M、Funayama M、Nishioka K、Hattori N
- Journal Title
  
  Journal of Human Genetics
  
  Volume: ー Issue: 9 Pages: 771-781
- DOI
  10.1038/s10038-020-0772-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14966, KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-20K07893, KAKENHI-PROJECT-19K17047
[Journal Article] Longitudinal changes in 18F-THK5351 PET in corticobasal syndrome2019
- Author(s)
  Ezura M, Kikuchi A, Ishiki A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Kobayashi M, Tano O, Nakashima I, Mugikura S, Iwata R, Taki Y, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
- Journal Title
  
  Eur J Neurol
  
  Volume: 26 Issue: 9 Pages: 1205-1211
- DOI
  10.1111/ene.13966
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-17K20083, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-16H05385, KAKENHI-PROJECT-17K09318, KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PROJECT-18K15538, KAKENHI-PROJECT-18H02771
[Journal Article] Unveiling the coupling of flotillin-1 and extracellular α-synuclein: relevance to dopamine transporter trafficking and Lewy body formation2019
- Author(s)
  Kobayashi J, Hasegawa T, Sugeno N, Yoshida S, Miki Y, Fukuda M, Kawahata I, Yamakuni T, Tomiyama A, Kawata Y, Ezura M, Kikuchi A, Baba T, Wakabayashi K, Takeda A, Aoki M
- Journal Title
  
  FASEB Journal
  
  Volume: 33 Issue: 9 Pages: 10240-10256
- DOI
  10.1096/fj.201802051r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-17H02076, KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PROJECT-18K19722, KAKENHI-PROJECT-19K07097
[Journal Article] DnaJ/Hsp40 family and Parkinson’s disease.2018
- Author(s)
  Hasegawa T, Yoshida S, Sugeno N, Kobayashi J, Aoki M.
- Journal Title
  
  Front Neurosci
  
  Volume: 11 Pages: 743-743
- DOI
  10.3389/fnins.2017.00743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PUBLICLY-17H05683
[Journal Article] Parkinson’s disease-linked DNAJC13 mutation aggravates α-synuclein-induced neurotoxicity through perturbation of endosomal trafficking.2018
- Author(s)
  Yoshida S, Hasegawa T, Suzuki M, Sugeno N, Kobayashi J, Ueyama M, Fukuda M, Ido-Fujibayashi A, Sekiguchi K, Ezura M, Kikuchi A, Baba T, Takeda A, Mochizuki H, Nagai Y and Aoki M.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 27 Issue: 5 Pages: 823-836
- DOI
  10.1093/hmg/ddy003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PROJECT-17K19658, KAKENHI-PROJECT-17K16134, KAKENHI-PROJECT-16H05325, KAKENHI-PUBLICLY-17H05682, KAKENHI-PUBLICLY-17H05683, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-15K09331
[Journal Article] Membrane Trafficking Illuminates a Path to Parkinson’s Disease2017
- Author(s)
  Hasegawa T, Sugeno N, Kikuchi A, Baba T, Aoki M.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 242 Issue: 1 Pages: 63-76
- DOI
  10.1620/tjem.242.63
- NAID
  130005679072
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PROJECT-17K09789, KAKENHI-PUBLICLY-17H05683, KAKENHI-PROJECT-26461303
[Journal Article] In vivo visualization of tau pathology using 18F-THK5351 PET in corticobasal syndrome.2016
- Author(s)
  Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Kobayashi M, Tano O, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Ezura M, Hiraoka K, Mugikura S, Takase K, Iwata R, Taki Y, Furukawa K, HArai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A，Aoki M.
- Journal Title
  
  Neurology
  
  Volume: 87 Issue: 22 Pages: 2309-2316
- DOI
  10.1212/wnl.0000000000003375
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01550, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-15K19767, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-16K15570
[Journal Article] ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways2016
- Author(s)
  Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M and Tanaka N
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 24997-24997
- DOI
  10.1038/srep24997
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461263, KAKENHI-PUBLICLY-15H01550, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-26461303
[Journal Article] 特集：パーキンソン病の治療-パーキンソン病の発症機序2015
- Author(s)
  菅野直人、長谷川隆文
- Journal Title
  
  Current Therapy
  
  Volume: 33 Pages: 14-19
- Data Source
  KAKENHI-PROJECT-26461263
[Journal Article] K63-linked ubiquitination by E3 Ubiquitin Ligase Nedd4-1 facilitates endosomal sequestration of internalized alpha-synuclein.2014
- Author(s)
  Sugeno N, Hasegawa T, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Aoki M, Takeda A.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 26 Pages: 18137-18151
- DOI
  10.1074/jbc.m113.529461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-26461303
[Journal Article] VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease.2014
- Author(s)
  Miura E, Hasegawa T, Konno M, Suzuki M, Sugeno N, Fujikake N, Geisler S, Tabuchi M, Oshima R, Kikuchi A, Baba T, Wada K, Nagai Y, Takeda A, Aoki M.
- Journal Title
  
  Neurobio Dis
  
  Volume: 71 Pages: 1-13
- DOI
  10.1016/j.nbd.2014.07.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24591286, KAKENHI-PUBLICLY-25110741, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-26670446
[Journal Article] Improvement of freezing of gait in patients with Parkinson’s disease by imagining bicycling.2014
- Author(s)
  Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Miura E, Oshima R, Aoki M, Takeda A.
- Journal Title
  
  Case Rep Neurol
  
  Volume: 6 Issue: 1 Pages: 92-95
- DOI
  10.1159/000362119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-25461264, KAKENHI-PROJECT-26461303
[Journal Article] Postural leg tremor in X-linked spinal and bulbar muscular atrophy.2014
- Author(s)
  Nishiyama A, Sugeno N, Tateyama M, Nishiyama S, Kato M, Aoki M.
- Journal Title
  
  J Clin Neurosci.
  
  Volume: 21 Issue: 5 Pages: 799-802
- DOI
  10.1016/j.jocn.2013.07.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461264
[Journal Article] Isolated posterior column lesion in a case with mixed connective tissue disease2014
- Author(s)
  Tomomi Shijo, Naoto Sugeno, Hiroshi Kuroda, Takafumi Hasegawa, Atsushi Takeda and Masashi Aoki
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: in press Issue: 3 Pages: 95-95
- DOI
  10.1111/ncn3.88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461264
[Journal Article] Retrospective analysis of Guillain-Barre syndrome and Fisher syndrome after the Great East Japan Earthquake2014
- Author(s)
  Hirofumi Tsuboi, Naoto Sugeno, Maki Tateyama, Ichiro Nakashima, Takafumi Hasegawa, Hiroshi Kuroda, Kimihiko Kaneko, Michiko Kobayashi, Aya Ishigaki, Juichi Fujimori and Masashi Aoki
- Journal Title
  
  Brain and Behavior
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461264
[Journal Article] K63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized alpha-synuclein2014
- Author(s)
  Sugeno N, Hasegawa T, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Aoki M, Takeda A.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461264
[Journal Article] Olfactory Dysfunction and Dementia in Parkinson's Disease.2014
- Author(s)
  Takeda A, Baba T, Kikuchi A, Hasegawa T, Sugeno N, Konno M, Miura E, Mori E.
- Journal Title
  
  J Parkinsons Dis.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461264
[Journal Article] Olfactory dysfunction and dementia in Parkinson's disease.2014
- Author(s)
  Takeda A, Baba T, Kikuchi A, Hasegawa T, Sugeno N, Konno M, Miura E, Mori E.
- Journal Title
  
  J Parkinsons Dis
  
  Volume: 4 Issue: 2 Pages: 181-187
- DOI
  10.3233/jpd-130277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-26461303
[Journal Article] Late-onset Charcot-Marie-Tooth disease type 1B due to a novel mutation in the extracellular disulfide bridge of MPZ gene.2013
- Author(s)
  Nishiyama S, Sugeno N, Tateyama M, Aoki M.
- Journal Title
  
  Clin Neurol Neurosurg.
  
  Volume: 115(2) Issue: 2 Pages: 208-209
- DOI
  10.1016/j.clineuro.2012.04.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study2013
- Author(s)
  Kikuchi A, Baba T, Hasegawa T, Kobayashi M, Sugeno N, Konno M, Miura E, Hosokai Y, Ishioka T, Nishio Y, Hirayama K, Suzuki K, Aoki M, Takahashi S, Fukuda H, Itoyama Y, Mori E, Takeda A.
- Journal Title
  
  BMJ Open
  
  Pages: 3-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Corticospinal tract signal changes in a patient with spinal and bulbar muscular atrophy2013
- Author(s)
  Naoto Sugeno, Ayumu Sunaguchi, Ayumi Nishiyama, Masaaki Kato and Masashi Aoki
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Issue: 3 Pages: 125-125
- DOI
  10.1111/j.2049-4173.2013.00025.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461264
[Journal Article] 維持透析中の４度肥満患者に発症したGuillain-Barre症候群に対して免疫グロブリン静注療法を行った１例2013
- Author(s)
  平出桜, 菅野直人, 坪井博文, 竪山真規, 石山勝也, 青木正志
- Journal Title
  
  神経治療
  
  Volume: 30 Pages: 57-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] 維持透析中の4度肥満患者に発症したGuillain-Barre症候群に対して免疫グロブリン静注療法を行った1例2013
- Author(s)
  平出桜,菅野直人,坪井博文,竪山真規,石山勝也,青木正志
- Journal Title
  
  神経治療
  
  Volume: 30 Pages: 57-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study.2013
- Author(s)
  Kikuchi A, Baba T, Hasegawa T, Kobayashi M, Sugeno N, Konno M, Miura E, Hosokai Y, Ishioka T, Nishio Y, Hirayama K, Suzuki K, Aoki M, Takahashi S, Fukuda H, Itoyama Y, Mori E, Takeda A.
- Journal Title
  
  BMJ Open
  
  Volume: 3(3) Pages: 2249-2249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Choreoathetosis in a patient with neuromyelitis optica spectrum disorder2013
- Author(s)
  Naoto Sugeno, Rumiko Izumi, Kazuhiro Kato, Ichiro Nakashima, Atsushi Takeda and Masashi Aoki
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Issue: 4 Pages: 154-156
- DOI
  10.1111/ncn3.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461264
[Journal Article] Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study2013
- Author(s)
  Akio Kikuchi, Toru Baba, Takafumi Hasegawa, Michiko Kobayashi, Naoto Sugeno, Masatoshi Konno, Emiko Miura, Yoshiyuki Hosokai, Toshiyuki Ishioka, Yoshiyuki Nishio, Kazumi Hirayama, Kyoko Suzuki, Masashi Aoki, ShokiTakahashi, Hiroshi Fukuda, Yasuto Itoyama, Etsuro Mori, Atsushi Takeda
- Journal Title
  
  BMJ Open
  
  Volume: 3 Issue: 3 Pages: e002249-e002249
- DOI
  10.1136/bmjopen-2012-002249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22611002, KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23591266, KAKENHI-PUBLICLY-24111502, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PROJECT-24659423, KAKENHI-PROJECT-25461264
[Journal Article] Hereditary neuropathy with liability to pressure palsy emerging after hypothyroidism2013
- Author(s)
  Kimihiko Kaneko, Naoto Sugeno, Maki Tateyama, Tatsuro Misu, Naoki Suzuki and Masashi Aoki
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Issue: 4 Pages: 160-161
- DOI
  10.1111/ncn3.41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461264
[Journal Article] 大脳皮質基底核変性症（CBD）2012
- Author(s)
  菅野　直人、武田　篤
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 30 Pages: 110-110
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Suppression of dynamin GTPase decreases alpha-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.2012
- Author(s)
  Konno M, Hasegawa T, Baba T, Miura E, Sugeno N, Kikuchi A, Fiesel FC, Sasaki T, Aoki M, Itoyama Y, Takeda A.
- Journal Title
  
  Mol Neurodegener
  
  Volume: 7 Issue: 1 Pages: 38-38
- DOI
  10.1186/1750-1326-7-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-23790974, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390222, KAKENHI-PROJECT-24659423, KAKENHI-PUBLICLY-24111502
[Journal Article] Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease: a 3 year longitudinal study2012
- Author(s)
  Baba T., Kikuchi A., Hirayama K., Nishio Y., Hosokai Y., Kanno S., Hasegawa T., Sugeno N., Konno M., Suzuki K., Takahashi S., Fukuda H., Aoki M., Itoyama Y., Mori E., Takeda A
- Journal Title
  
  Brain
  
  Volume: 135 Pages: 161-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] A case with anti-galactocerebroside antibody-positive Mycoplasma pneumoniae meningoencephalitis presenting secondary hypersomnia2012
- Author(s)
  Sugeno N., Kawaguchi N., Hasegawa T., Kuroda T., Nakashima I., Kanbayashi T., Kusunoki S., Aoki M.
- Journal Title
  
  Neurol. Sci
  
  Volume: 33 Pages: 1473-1476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] 両眼性の視力障害をきたしたMPO-ANCA関連肥厚性硬膜炎の1例2012
- Author(s)
  林聖也,菅野直人,西山修平,長谷川隆文,青木正志
- Journal Title
  
  臨床神経
  
  Volume: 52 Pages: 152-155
- NAID
  130004505250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] A case with anti-galactocerebroside antibody-positive Mycoplasma pneumoniae meningoencephalitis presenting secondary hypersomnia2012
- Author(s)
  Sugeno N
- Journal Title
  
  Neuro Sci
  
  Volume: － Issue: 6 Pages: 1473-1476
- DOI
  10.1007/s10072-012-1009-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229008, KAKENHI-PROJECT-23790974, KAKENHI-PROJECT-24621002
[Journal Article] Recurrent hypogeusia in a patient with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)2012
- Author(s)
  Kawaguchi N., Sugeno N., Endo K., Miura E., Misu T., Nakashima I., Itoyama Y.
- Journal Title
  
  J. Clin. Neurosci
  
  Volume: 19 Pages: 604-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease : a 3-year longitudinal study2012
- Author(s)
  BabaT, Kikuchi A, Hirayama K, Nishio Y, Hosokai Y, Kanno S, Hasegawa T, Sugeno N, Konno M, Suzuki K, et al
- Journal Title
  
  Brain
  
  Volume: 135 Issue: 1 Pages: 162-169
- DOI
  10.1093/brain/awr321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300345, KAKENHI-PROJECT-22611002, KAKENHI-PROJECT-22791104, KAKENHI-PUBLICLY-23119703, KAKENHI-PUBLICLY-23135502, KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24659423, KAKENHI-PUBLICLY-24111502
[Journal Article] 脳脊髄液中にのみ好酸球増多をみとめた再発性脳脊髄炎の1例2012
- Author(s)
  鈴木潤,菅野直人,西山修平,金子仁彦,三須建郎,竪山真規,遠藤俊毅,青木正志
- Journal Title
  
  臨床神経
  
  Volume: 52 Pages: 571-575
- NAID
  130004921058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Suppression of dynamin GTPase decreases alpha-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy2012
- Author(s)
  Konno M., Hasegawa T., Baba T., Miura E., Sugeno N., Kikuchi A., Fiesel F.C., Sasaki T., Aoki M., Itoyama Y., Takeda A.
- Journal Title
  
  Mol. Neurodegener
  
  Volume: 14 Pages: 38-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Recurrent hypogeusia in a patient with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)2012
- Author(s)
  Kawaguchi, N. Sugeno, N. Endo, K. Miura, E. Misu, T. Nakashima, I. Itoyama, Y.
- Journal Title
  
  Journal of clinical neuroscience
  
  Volume: 19 Issue: 4 Pages: 604-605
- DOI
  10.1016/j.jocn.2011.06.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974, KAKENHI-PROJECT-24591247
[Journal Article] Late-onset Charcot-Marie -Tooth disease type 1B due to a novel mutation in the extracellular disulfide bridge of MPZ gene2012
- Author(s)
  Nishiyama S., Sugeno N., Tateyama M., Aoki M.
- Journal Title
  
  Clin. Neurol. Neurosurg
  
  Volume: 115 Pages: 208-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2011
- Author(s)
  Kikuchi A., Baba T., Hasegawa T., Sugeno N., Konno M., Takeda A
- Journal Title
  
  Parkinsonism Relat. Disord
  
  Volume: 17(9) Pages: 698-700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2011
- Author(s)
  Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Takeda A
- Journal Title
  
  Parkinsonism & Related Disorders
  
  Volume: 17 Issue: 9 Pages: 698-700
- DOI
  10.1016/j.parkreldis.2011.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23790974
[Journal Article] Association of olfactory dysfunction and brain. Metabolism in Parkinson's disease2011
- Author(s)
  Baba T., Takeda A., Kikuchi A., Nishio Y., Hosokai Y., Hirayama K., Hasegawa T., Sugeno N., Suzuki K., Mori E., Takahashi S., Fukuda H., Itoyama Y.
- Journal Title
  
  Mov. Disord2011
  
  Volume: 26 Pages: 621-628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein2011
- Author(s)
  Hasegawa T., Konno M., Baba T., Sugeno N., Kikuchi A., Kobayashi M., Miura E., Tanaka N., Tamai K., Furukawa K., Arai H., Mori F., Wakabayashi K., Aoki M., Itoyama Y., Takeda A
- Journal Title
  
  PLoS One
  
  Volume: 6(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] The AAA-A TPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of alpha-Synuclein2011
- Author(s)
  Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Kobayashi M, Miura E, Tanaka N, Tamai K, Furukawa K, Arai H, Mori F, Wakabayashi K, Aoki M, Itoyama Y, Takeda A
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 12 Pages: 1-14
- DOI
  10.1371/journal.pone.0029460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-23790974
[Journal Article] Association of olfactory dysfunction and brain metabolism in Parkinson's disease2011
- Author(s)
  Baba T, Takeda A, Kikuchi A, Hishio Y, Hosokai Y, Hirayama K, Hasegawa T, Sugeno N, Suzuki K, et al
- Journal Title
  
  Movement disorder
  
  Volume: 26 Issue: 4 Pages: 621-628
- DOI
  10.1002/mds.23602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300345, KAKENHI-PROJECT-22611002, KAKENHI-PROJECT-22791104, KAKENHI-PUBLICLY-23135502, KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23790974
[Journal Article] Association of olfactory dysfunction and brain. Metabolism in Parkinson's disease.2011
- Author(s)
  Baba T, Takeda A, Kikuchi A, Nishio Y, Hosokai Y, Hirayama K, Hasegawa T, Sugeno N, Suzuki K, Mori E, Takahashi S, Fukuda H, Itoyama Y.
- Journal Title
  
  Mov Disord. 26巻
  
  Pages: 621-628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] パーキンソン病において神経保護作用を検証することはできるのか?2011
- Author(s)
  菅野　直人、武田　篤
- Journal Title
  
  内科
  
  Volume: 107 Pages: 1279-1284
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] Association of olfactory dysfunction and brain. Metabolism in Parkinson's disease.2011
- Author(s)
  Baba T, Takeda A, Kikuchi A, Nishio Y, Hosokai Y, Hirayama K, Hasegawa T, Sugeno N, Suzuki K, Mori E, Takahashi S, Fukuda H, Itoyama Y
- Journal Title
  
  Movement Disorders
  
  Volume: 22 Pages: 621-628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] しばらく待ってから導入 (診療controversy--medical decision makingのために非高齢パーキンソン病におけるドーパ剤の導入時期)2011
- Author(s)
  菅野　直人、武田　篤
- Journal Title
  
  内科
  
  Volume: 107 Pages: 707-711
- NAID
  40018771204
- Data Source
  KAKENHI-PROJECT-23790974
[Journal Article] DYT10(Episodic kinesiRenic dyskinesia 1 ; EKDI)2010
- Author(s)
  菅野直人, 武田篤
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 28 Pages: 771-773
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] Functional imaging studies of hyposmia in Parkinson's disease2010
- Author(s)
  Takeda A, Saito N, Baba T, Kikuchi A, Sugeno N, Kobayashi M, Hasegawa T, Itoyama Y
- Journal Title
  
  J Neurol Sci 289
  
  Pages: 36-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] LRRK2はαシヌクレインによって引き起こされる病理を増強する2010
- Author(s)
  菅野直人, 武田篤
- Journal Title
  
  PD Today
  
  Volume: 30 Pages: 14-15
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy.2010
- Author(s)
  Hasegawa T, Baba T, Kobayashi M, Konno M, Sugeno N, Kikuchi A, Itoyama Y, Takeda A.
- Journal Title
  
  Neurochem Int. 57巻
  
  Pages: 857-866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] In vivo visualization of alpha-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl] -6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy.2010
- Author(s)
  Kikuchi A, Takeda A, Okamura N, Tashiro M, Hasegawa T, Furumoto S, Kobayashi M, Sugeno N, Baba T, Miki Y, Mori F, Wakabayashi K, Funaki Y, Iwata R, Takahashi S, Fukuda H, Arai H, Kudo Y, Yanai K, Itoyama Y.
- Journal Title
  
  Brain. 133巻
  
  Pages: 1772-1778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] In vivo visualization of alpha-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy] benzoxazole positron emission tomography in multiple system atrophy.2010
- Author(s)
  Kikuchi A, Takeda A, Okamura N, Tashiro M, Hasegawa T, Furumoto S, Kohayashi M, Sugeno N, et al.
- Journal Title
  
  Brain
  
  Volume: 133 Pages: 1772-1778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] DYT10 (Episodic kinesigenic dyskinesia 1 ; EKD1)2010
- Author(s)
  菅野直人, 武田篤
- Journal Title
  
  Clinical Neuroscience 28巻
  
  Pages: 771-773
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] Functional imaging studies of hyposmia in Parkinson's disease.2010
- Author(s)
  Takeda A, Saito N, Baba T, Kikuchi A, Sugeno N, Kobayashi M, Hasegawa T, Itoyama Y.
- Journal Title
  
  J Neurol Sci. 289巻
  
  Pages: 36-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790830
[Journal Article] 電位の低下したミトコンドリアをいかにして処理するか?～PINK1,Parkinの持つ重要な役割について～2010
- Author(s)
  菅野直人, 武田篤
- Journal Title
  
  PD Today
  
  Volume: 32 Pages: 14-15
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] αシヌクレインのBAF複合体を介したエピゲノム制御機構の解明2023
- Author(s)
  中村貴彬、菅野直人、長谷川隆文、吉田隼、石山駿、佐藤一輝、青木正志
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] Re-analyses of scRNA-seq from human midbrain-like organoids2023
- Author(s)
  菅野　直人、中村　貴彬、長谷川　隆文、石山　駿、佐藤一輝, 吉田　隼、武田　篤、青木　正志
- Organizer
  第17回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] 遺伝性ジストニアDYT28における非侵襲的ヒストン修飾検出法の検討2022
- Author(s)
  菅野　直人、長谷川　隆文、中村　貴彬、石山　駿、吉田　隼、武田　篤、青木　正志
- Organizer
  第16回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] The protective effects of PRMT5 inhibition against alpha-synuclein-induced neurotoxicity2022
- Author(s)
  Naoto Sugeno, Takaaki Nakamura, Kensho Ikeda, Takafumi Hasegawa, Shun Ishiyama, Shun Yoshida, Michinori Ezura, Akio Kikuchi, Atsushi Takeda, Masashi Aoki
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] Alpha-synuclein repress neuronal gene expression through protein arginine methyltransferase 5 activation2022
- Author(s)
  Takaaki Nakamura, Naoto Sugeno, Kensho Ikeda, Takafumi Hasegawa, Shun Ishiyama, Shun Yoshida, Michinori Ezura, Akio Kikuchi, Atsushi Takeda, Masashi Aoki
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] Alpha-synuclein affects transcriptome through interacting with BAF complex2022
- Author(s)
  Takaaki Nakamura, Naoto Sugeno, Kensho Ikeda, Takafumi Hasegawa, Shun Ishiyama, Shun Yoshida, Atsushi Takeda, Masashi Aoki
- Organizer
  第16回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] Alpha-synuclein affects neuronal gene expression through histone methylation2021
- Author(s)
  Takaaki Nakamura, Naoto Sugeno, Takafumi Hasegawa, Shun Ishiyama, Shun Yoshida, Junpei Kobayashi, Michinori Ezura, Akio Kikuchi, Atsushi Takeda, Masashi Aoki
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] Alpha-synuclein affects neuronal gene expression through histone H4R3 symmetrical dimethylation2021
- Author(s)
  Takaaki Nakamura, Naoto Sugeno, Takafumi Hasegawa, Shun Ishiyama, Shun Yoshida, Junpei Kobayashi, Michinori Ezura, Akio Kikuchi, Atsushi Takeda, Masashi Aoki
- Organizer
  第15回パーキンソン病運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] パーキンソン病の分子病態について2020
- Author(s)
  菅野　直人
- Organizer
  第20回高松国際パーキンソン病シンポジウムin TOKYO
- Invited
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] Alpha-synuclein affects epigenetic profiles through interacting with BAF complex2020
- Author(s)
  Naoto Sugeno, Takaaki Nakamura, Takafumi Hasegawa, Junpei Kobayashi, Shun Yoshida, Shun Ishiyama, Michinori Ezura, Akio Kikuchi, Atsushi Takeda, Masashi Aoki
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07862
[Presentation] Hot Topics 01: Molecular and cellular basis of neurotoxicity caused by α-synuclein2019
- Author(s)
  Sugeno N
- Organizer
  第59回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09745
[Presentation] Alpha-synuclein interacts with BAF complex in nucleus2019
- Author(s)
  Sugeno N, Hasegawa T, Kobayashi J, Yoshida S, Ezura M, Kikuchi A, Takeda A, Aoki M.
- Organizer
  The 5th World Parkinson Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09745
[Presentation] Alpha-synuclein interacts with BAF complex in nucleus2019
- Author(s)
  Sugeno N, Hasegawa T, Kobayashi J, Yoshida S, Ezura M, Kikuchi A, Takeda A, Aoki M.
- Organizer
  International Congress of Parkinson’s Disease and Movement Disorders
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09745
[Presentation] Alpha-synuclein interacts with BAF complex in nucleus2018
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Junpei Kobayashi, Shun Yoshida, Michinori Ezura, Akio Kikuchi, Atsushi Takeda, Masashi Aoki
- Organizer
  第12回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-17K09745
[Presentation] Alpha-synuclein interacting protein in nucleus2018
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Junpei Kobayashi, Shun Yoshida, Michinori Ezura, Akio Kikuchi, Atsushi Takeda, Masashi Aoki
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09745
[Presentation] Alpha-synuclein enhances histone H3 lysine-9 dimethylation2017
- Author(s)
  Naoto Sugeno, Sandra Jackel, Aaron Voigt, Philipp Kahle
- Organizer
  International Congress of Parkinson's Disease and Movement Disorders
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09745
[Presentation] α-シヌクレイン核内結合タンパクの探索2017
- Author(s)
  菅野　直人、長谷川　隆文、小林　潤平、吉田　隼、江面　道典、菊池　昭夫、武田　篤、青木　正志
- Organizer
  MDSJ
- Data Source
  KAKENHI-PROJECT-17K09745
[Presentation] Knockdown of ESCRT-0 disrupts protein quality control and promotes ER stress-mediated neuronal cell death2015
- Author(s)
  Hasegawa T, Oshima R, Sugeno N, Tamai K, Kikuchi A, Takeda A, Tanaka N, Aoki M
- Organizer
  Neuroscience 2015
- Place of Presentation
  シカゴ、米国
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461263
[Presentation] CSF derived exosomal microRNA profile in patients with Parkinson’s disease2015
- Author(s)
  Hasegawa T, Sugeno N, Akio Kikuchi1, Oshima R, Yoshida S, Takeda A, Aoki M
- Organizer
  The MDS 19th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  サンディエゴ、米国
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461263
[Presentation] パーキンソン病における脳内α-シヌクレイン蛋白凝集体のPETによる画像化2015
- Author(s)
  198)菊池昭夫、馬場徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、大嶋龍司、岡村信行、古本祥三、谷内一彦、田代学、工藤幸司、糸山泰人、武田篤、青木正志
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] K63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized alpha-synuclein2014
- Author(s)
  Sugeno N, Hasegawa T, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Aoki M, Takeda A.
- Organizer
  18th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  スウェーデン、ストックホルム
- Data Source
  KAKENHI-PROJECT-25461264
[Presentation] Nedd4 E3 ubiquitin ligase facilitates the endosomal targeting of alpha-synuclein2013
- Author(s)
  Sugeno N. Hasegawa T. Konno M. Miura E. Kikuchi A. Aoki M. Takeda A.
- Organizer
  17th International Congress of Parkinson’s Disease and Movement Disorders
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] RNAi-mediated knockdown of VPS35 impairs α-synuclein degradation by inhibiting the maturation of cathepsin D2013
- Author(s)
  Miura E. Hasegawa T. Konno M. Sugeno N. Kikuchi A. Baba T. Aoki M. Takeda A.
- Organizer
  17th International Congress of Parkinson’s Disease and Movement Disorders
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] E3 ubiquitin ligase Nedd4はαシヌクレインのエンドソームへのターゲッティングに重要である2013
- Author(s)
  菅野直人、長谷川隆文、今野昌俊、三浦永美子、菊池昭夫、青木正志、武田篤
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京、東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25461264
[Presentation] E3 ubiquitin ligase Nedd4 is a key regulator of the endosomal targeting of a-synuclein2013
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Akio Kikuchi, Masashi Aoki, Atsushi Takeda
- Organizer
  17th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  オーストラリア、シドニー
- Data Source
  KAKENHI-PROJECT-25461264
[Presentation] Nedd4 E3 ubiquitin ligase facilitates the endosomal targeting of extracellular alpha-synuclein2013
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Akio Kikuchi, Masashi Aoki, Atsushi Takeda
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25461264
[Presentation] International Confer- ence on "Alpha-Synuclein in Parkinson's Disease and Related Neurodegenerative Diseases: From Mechanisms to Therapeutic Strategies"2013
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Akio Kikuchi, Masashi Aoki, Atsushi Takeda, E3 ubiquitinTanaka N., Tamai K., Furukawa K., Arai H., Mori F., Wakabayashi K., Aoki M., Itoyama Y., Takeda A.
- Organizer
  The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein. PLoS One. 6(12):e29460 (2011) 査読有10. Kikuchi A., Baba T., Hasegawa T.,ligase Nedd4 facilitates alpha-synuclein internalization
- Place of Presentation
  ドバイ、UAE
- Year and Date
  2013-03-02
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] E3 ubiquitin ligase Nedd4 facilitates alpha-synuclein internalization2013
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Akio Kikuchi, Masashi Aoki, Atsushi Takeda
- Organizer
  International Conference on “Alpha-Synuclein in Parkinson’s Disease and Related Neurodegenerative Diseases: From Mechanisms to Therapeutic Strategies”
- Place of Presentation
  ドバイ、UAE
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2013
- Author(s)
  Kikuchi A. Baba T. Hasegawa T. Sugeno N. Konno M. Aoki M. Takeda A.
- Organizer
  17th International Congress of Parkinson’s Disease and Movement Disorders
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] RNAi-mediated silencing of VPS35 exacerbates phenotypic and locomotor abnormalities in α-synuclein transgenic drosophila2013
- Author(s)
  Hasegawa T. Konno M. Miura E. Sugeno N. Nagai Y. Fujikake N. Suzuki M. Kikuchi A. Aoki M. Takeda A.
- Organizer
  17th International Congress of Parkinson’s Disease and Movement Disorders
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] K63-linked ubiquitination by Nedd4 facilitates endosomal sequestration of internalized α-synuclein2013
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Ryuji Oshima, Nobuyuki Tanaka, Masashi Konno, Emiko Miura, Akio Kikuchi, Toru Baba, Mitsunori Fukuda, Tadashi Anan, Mitsuyoshi Nakao, Sven Geisler, Masashi Aoki and Atsushi Takeda
- Organizer
  Neuroscience 2013
- Place of Presentation
  アメリカ合衆国、サン・ディエゴ
- Data Source
  KAKENHI-PROJECT-25461264
[Presentation] E3ユビキチンライゲースNedd4は細胞外αシヌクレインのエンドソームへのターゲッティングを制御する2013
- Author(s)
  菅野直人、長谷川隆文、今野昌俊、三浦永美子、大嶋龍司、菊池昭夫、青木正志、武田篤
- Organizer
  第7回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  東京、京王プラザホテル
- Data Source
  KAKENHI-PROJECT-25461264
[Presentation] Severe olfactory dysfunction is predictive of dementia associated with Parkinson's disease : A 3-year longitudinal study2012
- Author(s)
  Baba T., Kikuchi A., Hirayama K., Nishio Y., Hosokai Y., Kanno S., Hasegawa T., Sugeno N., Konno M., Miura E., Mori E., Takeda A.
- Organizer
  16th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] α-シヌクレイン細胞内取り込み機構の解析2012
- Author(s)
  菅野直人、長谷川隆文、今野昌俊、三浦永美子、菊池昭夫、馬場徹、青木正志、武田篤
- Organizer
  第６回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein2012
- Author(s)
  Hasegawa T., Konno M., Baba T., Sugeno N., Kikuchi A., Miura E., Takeda A.
- Organizer
  16th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] The role of Nedd4 in the internalization of alpha-synuclein2012
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Toru Baba, Akio Kikuchi, Masashi Aoki and Atsushi Takeda
- Organizer
  16th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  ダブリン、アイルランド
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] E3ユビキチンライゲースNedd4はαシヌクレイン内在化を制御する2012
- Author(s)
  菅野直人、長谷川隆文、今野昌俊、三浦永美子、菊池昭夫、武田篤、青木正志
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] α-シヌクレイン細胞内取り込み機構の解析2012
- Author(s)
  菅野直人、長谷川隆文、今野昌俊、三浦永美子、菊池昭夫、馬場徹、青木正志、武田篤
- Organizer
  第6回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] Dynamin GTPase activity decreases alpha-synuclein uptake in neuronal and oligodendroglial cells2012
- Author(s)
  Konno M., Hasegawa T., Baba T., Miura E., Sugeno N., Kikuchi A., Aoki M., Takeda A.
- Organizer
  16th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] Nedd4 participates in the internalization process of alpha-synuclein2012
- Author(s)
  Sugeno N., Hasegawa T., Konno M., Miura E., Baba T., Kikuchi A., Aoki M., Takeda A.
- Organizer
  16th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] The molecular basis of abnormal fear response in Parkinson’s disease. Interplay between alpha-synuclein and acid-sensing ion channel in amygdala.2011
- Author(s)
  Naoto Sugeno et al.
- Organizer
  15th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  トロント、カナダ
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] The molecular basis of abnormal fear response in Parkinson's disease. Interplay between alpha-synuclein and acid-sensing ion channel in amygdala2011
- Author(s)
  Naoto Sugeno, Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Toru Baba, Akio Kikuchi, Masashi Aoki and Atsushi Takeda
- Organizer
  15th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  ダブリン、アイルランド
- Year and Date
  2011-06-06
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] Gaucher病変異型fibroblastの細胞死におけるカテプシンBの関与2011
- Author(s)
  菅野直人、長谷川隆文、今野昌俊、三浦永美子、菊池昭夫、武田篤
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] Gaucher病変異型fibroblastの細胞死におけるカテプシンBの関与2011
- Author(s)
  菅野直人他
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-23790974
[Presentation] パーキンソン病における自己の感情の認知障害の検討2010
- Author(s)
  武田篤、馬場徹、菊池昭夫、長谷川隆文、菅野直人、小林理子、西尾憲之、森悦朗、平山和美、糸山泰人
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] Gaucher病変異型fibroblastのミトコンドリア複合体I阻害薬に対する脆弱性2010
- Author(s)
  菅野直人, 他6名
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] Gaucher病変異型fibroblastのミトコンドリア複合体I阻害薬に対する脆弱性2010
- Author(s)
  菅野直人、武田篤、長谷川隆文、今野昌俊、馬場徹、菊池昭夫、小林理子、糸山泰人
- Organizer
  第4回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] αシヌクレイン分泌・ライソゾーム移行を制御する細胞内膜動輸送系の探索2010
- Author(s)
  長谷川隆文、菅野直人, 他
- Organizer
  第4回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] パーキンソン病患者における嗅覚障害の神経基盤の検討2010
- Author(s)
  馬場徹、菊池昭夫、長谷川隆文、菅野直人、小林理子、武田篤、西尾慶之、森悦朗、平山和美、高橋昭喜、福田寛、糸山泰人
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] Gaucher病変異型fibroblastのミトコンドリア複合体I阻害薬に対する脆弱性2010
- Author(s)
  菅野直人、武田篤、長谷川隆文、小林理子、馬場徹、菊池昭夫、糸山泰人
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] 味覚障害を認めた慢性炎症性脱髄性多発根神経炎の1例2010
- Author(s)
  菅野直人, 他6名
- Organizer
  第21回日本末梢神経学会学術集会
- Place of Presentation
  フォレスト仙台
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] パーキンソン病患者における嗅覚障害の神経基盤の検討2010
- Author(s)
  馬場徹、菊池昭夫、長谷川隆文、菅野直人、小林理子、武田篤、西尾慶之、森悦朗、平山和美、高橋昭喜、福田寛、糸山泰人
- Organizer
  第4回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] パーキンソン病の運動症状出現前に認められたantecollisの検討2010
- Author(s)
  菅野直人、加藤量広、三浦永美子、川口典彦、井泉瑠美子、鈴木直輝、割田仁、中島一郎、武田篤
- Organizer
  第40回日本臨床神経生理学会
- Place of Presentation
  神戸
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] Gabapentin投与後に舞踏アテトーゼ運動を呈した視神経脊髄炎の一例2010
- Author(s)
  加藤量広、井泉瑠美子、菅野直人、長谷川隆文、中島一郎、糸山泰人
- Organizer
  第40回日本臨床神経生理学会
- Place of Presentation
  神戸
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] 細胞内へのα-シヌクレイン取り込み機構の解析2010
- Author(s)
  長谷川隆文、馬場徹、菅野直人、菊池昭夫、今野昌俊、武田篤、糸山泰人
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-23
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] Gaucher病変異型fibroblastのミトコンドリア複合体I阻害薬に対する脆弱性2010
- Author(s)
  菅野直人, 他6名
- Organizer
  第4回パーキンソン病運動障害疾患コングレス
- Place of Presentation
  京都ホテルオークラ
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] 味覚障害を認めた慢性炎症性脱髄性多発根神経炎の1例2010
- Author(s)
  菅野直人、川口典彦、遠藤薫、三須建郎、中島一郎、竪山真規、糸山泰人
- Organizer
  第21回日本末梢神経学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] 多系統萎縮症における脳内α-シヌクレイン蛋白凝集体のPETによる画像化2010
- Author(s)
  菊池昭夫、武田篤、長谷川隆文、小林理子、菅野直人、馬場徹、岡村信行、古本祥三、谷内一彦、田代学、工藤幸司、糸山泰人
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] Cytoprotective effects of extracellular dopamine under the dopamine overproduction2009
- Author(s)
  菅野直人, 他6名
- Organizer
  13th International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  Le Palais Des Congres de Paris(フランス)
- Year and Date
  2009-06-09
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] チロシン水酸化酵素発現細胞における細胞外ドパミンの保護的役割2009
- Author(s)
  菅野直人, 他6名
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-21790830
[Presentation] Nedd4 regulates internalization and endosomal targeting of alpha-synuclein.
- Author(s)
  Hasegawa T, Sugeno N, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Takeda A, Aoki M
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461263
[Presentation] Functional ESCRT machinery is required for the clearance of aggregate-prone proteins associated with neurodegenerative diseases
- Author(s)
  Oshima R. Hasegawa T. Sugeno N. Konno M. Miura E. Kikuchi A. Tamai K. Takeda A. Tanaka N. Aoki M.
- Organizer
  18th International Congress of Parkinson’s Disease and Movement Disorders
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2014-06-07 – 2014-06-12
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] In vivo visualization of α-synuclein deposition by carbon-11-labeled 2-(2-[2-dimethylaminothiazol-5-yl]ethenyl)−6-(2-[fluoro]ethoxy)benzoxazole positron emission tomography in Parkinson's disease
- Author(s)
  Kikuchi A. Okamura N. Tashiro M. Hasegawa T. Sugeno N. Baba T. Konno M. Miura E. Oshima R. Furumoto S. Funaki Y. Iwata R. Takahashi S. Fukuda H. Arai H. Kudo Y. Yanai K. Itoyama Y. Aoki M. Takeda A.
- Organizer
  18th International Congress of Parkinson’s Disease and Movement Disorders
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2014-06-07 – 2014-06-12
- Data Source
  KAKENHI-PROJECT-24390219
[Presentation] K63-linked ubiquitination by Nedd4 facilitates endosomal sequestration of internalized alpha-synuclein, 18th International Congress of Parkinson’s Disease and Movement Disorders
- Author(s)
  Sugeno N. Hasegawa T. Tanaka N. Oshima R. Konno M. Miura E. Kikuchi A. Baba T. Fukuda M. Geisler S. Aoki M. Takeda A.,
- Organizer
  18th International Congress of Parkinson’s Disease and Movement Disorders
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2014-06-07 – 2014-06-12
- Data Source
  KAKENHI-PROJECT-24390219

1. HASEGAWA Takafumi (70361079)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
2. TAKEDA ATSUSHI (70261534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
3. KIKUCHI Akio (80463785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
4. Nagai Yoshitaka (60335354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HOSOKAI Yoshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 大垣光太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 若林孝一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 森文秋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 青木正志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 鈴木匡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Sugeno Naoto 菅野 直人

SUGENO Naoto 菅野 直人

Research Projects

Research Products

Co-Researchers

Exploring the role of alpha-synuclein in epigenetic regulation by histone remodeling factor, WDR5Principal Investigator

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α-シヌクレインを介したOPRM1遺伝子の転写調節機構の解明Principal Investigator

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Histone modification induced by alpha-synucleinPrincipal Investigator

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Zeroing in on aberrant membrane trafficking in molecular pathogenesis of Parkinson's disease

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内在化αシヌクレインにおけるESCRTを中心とした小胞輸送に関する研究Principal Investigator

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Early diagnosis and treatment of Parkinson disease dementia

Principal Investigator

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Glucocerebrosidase mutation accelerates alpha-synuclein cytotoxityPrincipal Investigator

Principal Investigator

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Cytotoxic effect induced by phosphorylated alpha-synuclein and dopaminePrincipal Investigator

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[Book] 運動失調のみかた,考えかた III-8 プリオン仮説2017

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[Journal Article] Alpha‐synuclein promotes PRMT5‐mediated H4R3me2s histone methylation by interacting with the BAF complex2023

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[Journal Article] Detection of Modified Histones from Oral Mucosa of a Patient with DYT-KMT2B Dystonia2023

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[Journal Article] Sortilin acts as an endocytic receptor for α‐synuclein fibril2023

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[Journal Article] Unraveling the Complex Interplay between Alpha-Synuclein and Epigenetic Modification2023

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[Journal Article] High prevalence of serum anti-NH2-terminal of α-enolase antibodies in patients with multiple system atrophy and corticobasal syndrome2021

Sugeno Naoto 菅野直人

SUGENO Naoto 菅野直人

[Book] 運動失調のみかた,考えかた　III-8 プリオン仮説2017