Nishino Mitsuko 西野美都子

… Alternative Names

NISHINO Mitsuko 西野美都子

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Researcher Number	30510440
Other IDs
Affiliation (Current)	2025: 大阪大学, 産業科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 大阪大学, 産業科学研究所, 准教授 2015 – 2019: 大阪大学, 産業科学研究所, 助教 2017: 大阪大学, 産業科学研究所, 特任助教 2014: 大阪大学, 産業科学研究所, 特任助教 2012: 大阪大学, 産業科学研究所, 特任助教(常勤) 2009 – 2012: Osaka University, 産業科学研究所, 特任助教 2010: Osaka University, 産業科学研究所, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Bacteriology (including mycology) / Biological pharmacy / Basic Section 62010:Life, health and medical informatics-related Except Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Medium-sized Section 62:Applied informatics and related fields / Biological Sciences
Keywords	Principal Investigator 細菌 / 多剤耐性菌 / 感染症 / 機械学習 / 電子顕微鏡 / 病原性 / サルモネラ / トランスポーター / 薬剤排出 / 多剤耐性 … More / 人工知能 / 画像判別 / 深層学習 / 画像解析 / 緑膿菌 / 大腸菌 / 宿主相互作用 / 薬剤耐性 / ABC型 / マクロライド / Mac / ATP / ABC / 排出 / 異物 / MacAB / 異物排出 / 化学療法 / 排出蛋白質 / 輸送体 / オートファジー … More Except Principal Investigator 細菌 / 薬剤耐性 / 複合体 / 制御 / RND / 阻害 / 複合体形成 / 異物排出 / AI / 画像 / 顕微鏡 / バイオメトリクス / 薬剤耐性菌 / 判別 / 極性輸送 / TGN / リサイクリングエンドソーム / 電子顕微鏡 / GPI / 電顕トモグラフィー / ノックアウトマウス / Rab / GPIアンカータンパク / 細胞極性 / 糖転移酵素 / GPI修飾酵素 / 上皮細胞 / 選別輸送 / 選別輸送ゾーン / ゾーン / 糖鎖合成酵素 / ゴルジ体 Less

Dynamic analysis of the formation mechanism of the xenobiotic efflux complexs
- Principal Investigator
  
  西野邦彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Osaka University
Biometric study of drug resistant bacteria
- Principal Investigator
  
  西野邦彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  Osaka University
AIによる多剤耐性菌モルフォミクスとバイオインフォマティクスの融合研究Principal Investigator
- Principal Investigator
  
  西野美都子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Osaka University
Discrimination of multi-drug resistant bacteria by machine learning.Principal Investigator
- Principal Investigator
  
  Nishino Mitsuko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Osaka University
Significance of polarized transport zones in organelles during polarized transport in epithelial cells
- Principal Investigator
  
  Harada Akihiro
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Regulation of bacterial pathogenicity by the ABC transporterPrincipal Investigator
- Principal Investigator
  
  Nishino Mitsuko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Osaka University
Inhibitor development and the functional elucidation of the drug efflux transporter which participates in multidrug resistance and pathogenic revelationPrincipal Investigator
- Principal Investigator
  
  NISHINO Mitsuko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
Study on defense mechanisms of bacteria and host cells in infection.Principal Investigator
- Principal Investigator
  
  NISHINO Mitsuko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University

[Book] 組織細胞化学技術プロトコール組織細胞化学の挑戦 -臨床応用研究への飛躍-見る!-電子顕微鏡の基礎と応用- 「電子線トモグラフィーによる細胞小器官の3D解析」2012
- Author(s)
  西野-林美都子
- Publisher
  日本組織細胞化学会
- Data Source
  KAKENHI-PROJECT-23790085
[Book] オートファジー「電子顕微鏡を用いたオートファジー解析」2012
- Author(s)
  西野―林美都子（水島昇・吉森保/編）
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23790085
[Book] オートファジー「電子顕微鏡を用いたオートファジー解析」2012
- Author(s)
  西野-林美都子(水島昇・吉森保/編)
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23790085
[Book] 組織細胞化学技術プロトコール組織細胞化学の挑戦 -臨床応用研究への飛躍- 見る！-電子顕微鏡の基礎と応用-「電子線トモグラフィーによる細胞小器官の3D解析」2012
- Author(s)
  西野―林美都子
- Publisher
  日本組織細胞化学会
- Data Source
  KAKENHI-PROJECT-23790085
[Journal Article] Major primary bile salts repress Salmonella enterica serovar Typhimurium invasiveness partly via the efflux regulatory locus ramRA2024
- Author(s)
  Giraud Etienne、Baucheron Sylvie、Foubert Isabelle、Doublet Benoit、Nishino Kunihiko、Cloeckaert Axel
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 15 Pages: 1338261-1338261
- DOI
  10.3389/fmicb.2024.1338261
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27322
[Journal Article] Changes in the expression of mexB, mexY, and oprD in clinical Pseudomonas aeruginosa isolates2024
- Author(s)
 Y. Matsumoto, S. Yamasaki, K. Hayama, R. Iino, H. Noji, A. Yamaguchi, and K. Nishino
- Journal Title
 
 Proceedings of the Japan Academy, Series B
 
 Volume: 100 Issue: 1 Pages: 57-67
- DOI
 10.2183/pjab.100.006
- ISSN
 0386-2208, 1349-2896
- Year and Date
 2024-01-11
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21K16318, KAKENHI-PROJECT-23K27322
[Journal Article] Investigating multidrug efflux pumps associated with fatty acid salt resistance in Escherichia coli2023
- Author(s)
  Yamasaki Seiji、Yoneda Tomohiro、Ikawa Sota、Hayashi-Nishino Mitsuko、Nishino Kunihiko
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 14 Pages: 954304-954304
- DOI
  10.3389/fmicb.2023.954304
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19831, KAKENHI-PROJECT-21K16318, KAKENHI-PROJECT-23K21717
[Journal Article] An Electron Tomographic Analysis of Giantin-Deficient Golgi Proposes a New Function of the Golgin Protein Family2023
- Author(s)
  Satoh Ayano、Hayashi-Nishino Mitsuko、Nishino Kunihiko
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2557 Pages: 235-246
- DOI
  10.1007/978-1-0716-2639-9_15
- ISBN
  9781071626382, 9781071626399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21717
[Journal Article] Functional and structural characterization of Streptococcus pneumoniae pyruvate kinase involved in fosfomycin resistance2023
- Author(s)
  Taguchi Atsushi、Nakashima Ryosuke、Nishino Kunihiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 7 Pages: 104892-104892
- DOI
  10.1016/j.jbc.2023.104892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14518, KAKENHI-PROJECT-23K27322
[Journal Article] Drug resistance and physiological roles of RND multidrug efflux pumps in Salmonella enterica, Escherichia coli and Pseudomonas aeruginosa2023
- Author(s)
  Yamasaki Seiji、Zwama Martijn、Yoneda Tomohiro、Hayashi-Nishino Mitsuko、Nishino Kunihiko
- Journal Title
  
  Microbiology
  
  Volume: 169 Issue: 6 Pages: 001322-001322
- DOI
  10.1099/mic.0.001322
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14346, KAKENHI-PROJECT-21K16318, KAKENHI-PROJECT-23K21717, KAKENHI-PROJECT-23K27322
[Journal Article] Proximal Binding Pocket Arg717 Substitutions in Escherichia coli AcrB Cause Clinically Relevant Divergencies in Resistance Profiles2022
- Author(s)
  Zwama Martijn、Nishino Kunihiko
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 66 Issue: 4
- DOI
  10.1128/aac.02392-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19831, KAKENHI-PROJECT-20K16242
[Journal Article] Analysis of multidrug efflux transporters in resistance to fatty acid salts reveals a TolC-independent function of EmrAB in Salmonella enterica2022
- Author(s)
  Yoneda Tomohiro、Sakata Hiroki、Yamasaki Seiji、Hayashi-Nishino Mitsuko、Nishino Kunihiko
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 4 Pages: e0266806-e0266806
- DOI
  10.1371/journal.pone.0266806
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19451, KAKENHI-PROJECT-22K19831, KAKENHI-PROJECT-21K16318, KAKENHI-PROJECT-23K21717
[Journal Article] Evaluation of efflux pump inhibitors of MexAB- or MexXY-OprM in Pseudomonas aeruginosa using nucleic acid dyes2022
- Author(s)
  Masasuke Fujiwara, Seiji Yamasaki, Yuji Morita, Kunihiko Nishino
- Journal Title
  
  Journal of infection and chemotherapy
  
  Volume: 28 Issue: 5 Pages: 595-601
- DOI
  10.1016/j.jiac.2022.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07547, KAKENHI-PROJECT-18K14902, KAKENHI-PROJECT-22K19831, KAKENHI-PROJECT-21K16318
[Journal Article] Identification of Bacterial Drug-Resistant Cells by the Convolutional Neural Network in Transmission Electron Microscope Images2022
- Author(s)
  Hayashi-Nishino Mitsuko、Aoki Kota、Kishimoto Akihiro、Takeuchi Yuna、Fukushima Aiko、Uchida Kazushi、Echigo Tomio、Yagi Yasushi、Hirose Mika、Iwasaki Kenji、Shin’ya Eitaro、Washio Takashi、Furusawa Chikara、Nishino Kunihiko
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 13
- DOI
  10.3389/fmicb.2022.839718
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21717
[Journal Article] Spatial Characteristics of the Efflux Pump MexB Determine Inhibitor Binding2022
- Author(s)
  Yamasaki Seiji、Koga Naoki、Zwama Martijn、Sakurai Keisuke、Nakashima Ryosuke、Yamaguchi Akihito、Nishino Kunihiko
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 66 Issue: 11
- DOI
  10.1128/aac.00672-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19831, KAKENHI-PROJECT-21K16318, KAKENHI-PROJECT-20K16242
[Journal Article] Function and Inhibitory Mechanisms of Multidrug Efflux Pumps2021
- Author(s)
  Nishino Kunihiko、Yamasaki Seiji、Nakashima Ryosuke、Zwama Martijn、Hayashi-Nishino Mitsuko
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 12 Pages: 737288-737288
- DOI
  10.3389/fmicb.2021.737288
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14902, KAKENHI-PROJECT-20K16242, KAKENHI-PROJECT-21K16318, KAKENHI-PROJECT-23K21717
[Journal Article] Palmitoylated CKAP4 regulates mitochondrial functions through an interaction with VDAC2 at ER?mitochondria contact sites2020
- Author(s)
  Harada Takeshi、Sada Ryota、Osugi Yoshito、Matsumoto Shinji、Matsuda Tomoki、Hayashi-Nishino Mitsuko、Nagai Takeharu、Harada Akihiro、Kikuchi Akira
- Journal Title
  
  Journal of Cell Science
  
  Volume: 133 Issue: 21
- DOI
  10.1242/jcs.249045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06956, KAKENHI-PROJECT-20K07357, KAKENHI-PROJECT-16H06374, KAKENHI-PROJECT-18H02594, KAKENHI-PROJECT-17K08633, KAKENHI-PROJECT-19K22563, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06422
[Journal Article] The Golgin Protein Giantin Regulates Interconnections Between Golgi Stacks2019
- Author(s)
  Satoh Ayano、Hayashi-Nishino Mitsuko、Shakuno Takuto、Masuda Junko、Koreishi Mayuko、Murakami Runa、Nakamura Yoshimasa、Nakamura Toshiyuki、Abe-Kanoh Naomi、Honjo Yasuko、Malsam Joerg、Yu Sidney、Nishino Kunihiko
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 7 Pages: 160-160
- DOI
  10.3389/fcell.2019.00160
- NAID
  120006733903
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05894, KAKENHI-PROJECT-17H01214, KAKENHI-PROJECT-17K08827
[Journal Article] Phenotype microarray analysis of the drug efflux systems in Salmonella enterica serovar Typhimurium2016
- Author(s)
  Yamasaki S, Fujioka T, Hayashi K, Yamasaki S, Hayashi-Nishino M, Nishino K
- Journal Title
  
  J Infect Chemother
  
  Volume: in press Issue: 11 Pages: 780-784
- DOI
  10.1016/j.jiac.2016.03.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26713004, KAKENHI-PROJECT-26460524
[Journal Article] Multidrug efflux pumps contribute to Escherichia coli biofilm maintenance2015
- Author(s)
  Seiji Yamasaki, Li-Yuan Wang, Takahiro Hirata, Mitsuko Hayashi-Nishino, Kunihiko Nishino
- Journal Title
  
  International Journal of Antimicrobial Agents
  
  Volume: 45 Issue: 4 Pages: 439-441
- DOI
  10.1016/j.ijantimicag.2014.12.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J30009, KAKENHI-PROJECT-26460524, KAKENHI-PROJECT-26713004
[Journal Article] Effect of methylglyoxal on multidrug-resistant Pseudomonas aeruginosa.2014
- Author(s)
  Katsuhiko Hayashi, Aiko Fukushima, Mitsuko Hayashi-Nishino, and Kunihiko Nishino
- Journal Title
  
  frontiers in Microbiology
  
  Volume: 5 Pages: 180-180
- DOI
  10.3389/fmicb.2014.00180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J01576, KAKENHI-PROJECT-26460524, KAKENHI-PROJECT-26713004
[Journal Article] Morphological analysis of autophagy2013
- Author(s)
  K. Tabata, M. Hayashi-Nishino, T. Noda, A.Yamamoto, T. Yoshimori
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 931 Pages: 449-466
- DOI
  10.1007/978-1-62703-056-4_23
- ISBN
  9781627030557, 9781627030564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790085
[Journal Article] Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection2012
- Author(s)
  H. Niu, Q. Xiong, A. Yamamoto, M.Hayashi-Nishino, Y. Rikihisa
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Issue: 51 Pages: 20800-20807
- DOI
  10.1073/pnas.1218674109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790085
[Journal Article] Impact of Hfq on the intrinsic drug resistance of Salmonella enterica serovar Typhimurium2012
- Author(s)
  M. Hayashi-Nishino, A. Fukushima, K.Nishino
- Journal Title
  
  Front. Microbiol.
  
  Volume: 3 Pages: 205-205
- DOI
  10.3389/fmicb.2012.00205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790085
[Journal Article] Small RNA-mediated bacterial multidrug resistance2011
- Author(s)
  Nishino K, Yamasaki S, Hayashi-Nishino M,Yamaguchi A
- Journal Title
  
  Jpn J Chemother
  
  Volume: 59 Pages: 1-7
- Data Source
  KAKENHI-PROJECT-23790085
[Journal Article] AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium2011
- Author(s)
  Yamasaki S, Nagasawa S, Hayashi-NishinoM,Yamaguchi A, Nishino K
- Journal Title
  
  J Antibiot (Nature Publishing Group)
  
  Volume: 64 Pages: 433-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790085
[Journal Article] 電子線トモグラフィーによるオートファジーの解析2010
- Author(s)
  西野-林美都子
- Journal Title
  
  顕微鏡 45
  
  Pages: 77-79
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Impact of the RNA chaperone Hfq on multidrug resistance in Escherichia coli.2010
- Author(s)
  Yamada J., Yamasaki S., Hirakawa H., Hayashi-Nishino M., Yamaguchi A., Nishino K.
- Journal Title
  
  J.Antimicrob.Chemother. 65
  
  Pages: 853-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation.2010
- Author(s)
  Hayashi-Nishino, M., et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 301-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Effect of NlpE overproduction on multidrug resistance in Escherichia coli.2010
- Author(s)
  Nishino, K., et al
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 54 Pages: 2239-2243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] 電子線トモグラフィーによるオートファジーの解析2010
- Author(s)
  西野-林美都子
- Journal Title
  
  顕微鏡
  
  Volume: 45 Pages: 77-79
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Effect of overexpression of small noncoding DsrA RNA on multidrug efflux in Escherichia coli.2010
- Author(s)
  Nishino K., Yamasaki S., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  J Antimicrob.Chemother 66
  
  Pages: 291-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation.2010
- Author(s)
  Hayashi-Nishino M., Fujita N., Noda T., Yamaguchi A., Yoshimori T., Yamamoto A.
- Journal Title
  
  Autophagy 6
  
  Pages: 301-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Indoleenhances acid resistance in Escherichia coli.2010
- Author(s)
  Hirakawa H., Hayashi-Nishino M., Yamaguchi A., Nishino K.
- Journal Title
  
  Microb.Pathog.(Co-firstauthors) 49
  
  Pages: 90-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Effect of NlpE overproduction on multidrug resistance in Escherichia coli.2010
- Author(s)
  Nishino K., Yamasaki S., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  Antimicrob Agents Chemother. 54
  
  Pages: 2239-2243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF.2009
- Author(s)
  Nishino, K., et al.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 53
  
  Pages: 3541-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation.2009
- Author(s)
  Hayashi-Nishino, M., et al.
- Journal Title
  
  Nature Cell Biology 11
  
  Pages: 1433-1437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Role of the AraC-XylS family regulator YdeO in multi-drug resistance of Escherichia coli.2009
- Author(s)
  Nishino K., Senda Y., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  J.Antibiot. 62
  
  Pages: 251-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation.2009
- Author(s)
  Hayashi-Nishino M., Fujita N., Noda T., Yamaguchi A., Yoshimori T., Yamamoto A.
- Journal Title
  
  Nature Cell Biology 11
  
  Pages: 1433-1437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Role of the AraC-XylS family regulator YdeO in multi-drug resistance of Escherichia coli.2009
- Author(s)
  Nishino, K., et al.
- Journal Title
  
  The Journal of Antibiotics 62
  
  Pages: 251-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF.2009
- Author(s)
  Nishino K., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  Antimicrob.Agents Chemother. 53
  
  Pages: 3541-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Effect of overexpression of small noncoding DsrA RNA on multidrug efflux in Escherichia coli
- Author(s)
  Nishino, K., et al
- Journal Title
  
  Journal of Antimicrobial Chemotherapy
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Effect of NlpE overproduction on multidrug resistance in Escherichia coli.
- Author(s)
  Nishino, K., et al.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Journal Article] Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation.
- Author(s)
  Hayashi-Nishino, M., et al.
- Journal Title
  
  Autophagy (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] 光学顕微鏡画像を用いた薬剤耐性菌のバイオインフォマティクス解析2024
- Author(s)
  池邉美季、青木工太、西野美都子、西野邦彦
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K21717
[Presentation] Bioinformatic analysis of morphological features of antibiotic-resistant bacteria2024
- Author(s)
  Ikebe, M., Aoki, K., Hayashi-Nishino, M., Nishino, K.
- Organizer
  The 27th SANKEN International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21717
[Presentation] Correlation analysis of bacterial cell morphology and multidrug resistance2023
- Author(s)
  Ikebe, M., Aoki, K., Hayashi-Nishino, M., Nishino, K.
- Organizer
  9th Symposium on Antimicrobial Resistance in Animals and the Environment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21717
[Presentation] Development of Universal Inhibitors of Drug Efflux Pumps to Overcome Multidrug-Resistant Pseudomonas aeruginosa Infections2023
- Author(s)
  Kunihiko Nishino
- Organizer
  9th Symposium on Antimicrobial Resistance in Animals and the Environment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27322
[Presentation] Development of Universal Inhibitors of Drug Efflux Pumps to Overcome Multidrug-Resistant Pseudomonas aeruginosa Infections2023
- Author(s)
  Kunihiko Nishino
- Organizer
  Gordon Research Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19831
[Presentation] 細菌多剤耐性化と新規治療戦略2022
- Author(s)
  西野邦彦
- Organizer
  第20回　PhotoLIFEワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-22K19831
[Presentation] 電子顕微鏡画像における薬剤耐性菌株の識別と形態的特徴の比較2019
- Author(s)
  1.長野章宏、青木工太、西野美都子、福島愛子、岩崎憲治、古澤力、アンドレイグルシニコフ、越後富夫、西野邦彦、八木康史
- Organizer
  第215回情報処理学会コンピュータビジョンとイメージメディア研究会
- Data Source
  KAKENHI-PLANNED-17H06422
[Presentation] 電子顕微鏡画像における薬剤耐性菌株の識別と形態的特徴の比較2019
- Author(s)
  長野章宏、青木工太、西野美都子、福島愛子、岩崎憲治、古澤力、アンドレイグルシニコフ、越後富夫、西野邦彦、八木康史
- Organizer
  第215回情報処理学会コンピュータビジョンとイメージメディア研究会
- Data Source
  KAKENHI-PROJECT-17K08827
[Presentation] Characterization of the novel inhibitor for protein secretion.2018
- Author(s)
  4.Ayano Satoh, Hideyuki Suzuki, Mitsuko Hayashi-Nishino, Kunihiko Nishino and Yuta Nishina
- Organizer
  第70回日本細胞生物学会・第51回日本発生生物学会合同大会
- Data Source
  KAKENHI-PLANNED-17H06422
[Presentation] Characterization of the novel inhibitor for protein secretion.2018
- Author(s)
  Ayano Satoh, Hideyuki Suzuki, Mitsuko Hayashi-Nishino, Kunihiko Nishino and Yuta Nishina
- Organizer
  第70回日本細胞生物学会・第51回日本発生生物学会合同大会
- Data Source
  KAKENHI-PROJECT-17K08827
[Presentation] A 3D modeling of Golgi stacks in giantin knockdown cells.2018
- Author(s)
  Takuto Shakuno, Mitsuko Hayashi-Nishino, Kunihiko Nishino and Ayano Satoh
- Organizer
  第70回日本細胞生物学会・第51回日本発生生物学会合同大会
- Data Source
  KAKENHI-PROJECT-17K08827
[Presentation] A 3D modeling of Golgi stacks in giantin knockdown cells.2018
- Author(s)
  3.Takuto Shakuno, Mitsuko Hayashi-Nishino, Kunihiko Nishino and Ayano Satoh
- Organizer
  第70回日本細胞生物学会・第51回日本発生生物学会合同大会
- Data Source
  KAKENHI-PLANNED-17H06422
[Presentation] ゴルジンタンパク質であるGiantinはゴルジ体ゾーンの形成に関与するか？2018
- Author(s)
  佐藤あやの、杓野拓斗、西野-林美都子、西野邦彦
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08827
[Presentation] 畳み込みニューラルネットワークを用いた電子顕微鏡像における薬剤耐性菌の識別2018
- Author(s)
  長野章宏、青木工太、武内優奈、西野美都子、西野邦彦、古澤力、岩崎憲治、越後富夫、八木康史
- Organizer
  第207回CVIM研究発表会
- Data Source
  KAKENHI-PROJECT-17K08827
[Presentation] ゴルジンタンパク質であるGiantinはゴルジ体ゾーンの形成に関与するか？2018
- Author(s)
  佐藤あやの、杓野拓斗、西野-林美都子、西野邦彦
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-17H06422
[Presentation] Development of Novel Therapeutic Strategies to Tackle Multidrug-Resistant Pathogens2016
- Author(s)
  Mitsuko Hayashi-Nishino, Yoshimi Matsumoto and Kunihiko Nishino
- Organizer
  International Symposium Salmonella and Salmonellosis
- Place of Presentation
  Saint-Malo, France
- Year and Date
  2016-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460524
[Presentation] Electron/immuno-electron tomography of autophagosomal membranes and bacterial multidrug efflux systems2015
- Author(s)
  Mitsuko Hayashi-Nishino and Kunihiko Nishino
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  ハワイ（アメリカ合衆国）
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460524
[Presentation] 多剤耐性病原細菌の新規治療戦略2015
- Author(s)
  西野美都子
- Organizer
  附置研究所間アライアンスによるナノとマクロをつなぐ物質・デバイス・システム創製戦略プロジェクト　医療材料・デバイス・システムグループG3 分科会
- Place of Presentation
  大阪府・大阪市
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-26460524
[Presentation] トランスポーター制御による細菌恒常性維持機構の解明と新規治療戦略の開発2014
- Author(s)
  西野邦彦、Aixin Yan、林克彦、山崎聖司、福島愛子、松本佳巳、西野美都子、Danny KC Fung, Ma Yongzheng, Sun Jingjing, Gao Xiang, Kai Yong, Deng Ziqing
- Organizer
  大阪大学国際共同研究促進プログラム報告会
- Place of Presentation
  大阪
- Year and Date
  2014-12-09
- Data Source
  KAKENHI-PROJECT-26460524
[Presentation] 電子線トモグラフィーによる細胞小器官の 3D 解析2012
- Author(s)
  西野美都子
- Organizer
  第37回組織細胞化学講習会
- Place of Presentation
  大阪
- Year and Date
  2012-08-02
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Development of novel therapeutic strategies to tackle multidrug-resistant pathogens2012
- Author(s)
  Nishino, K., K. Hayashi, S. Yamasaki, S. Yamasaki, Y. Matsumoto, M. Hayashi-Nishino, A. Yamaguchi
- Organizer
  New Frontiers of Metabolism Research in Biomedical Sciences
- Place of Presentation
  Tokyo
- Year and Date
  2012-09-27
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Immuno-electron tomography for elucidation of localization of the multidrug efflux pump in Salmonella2012
- Author(s)
  Hayashi-Nishino, M., A. Yamaguchi, and K.Nishino
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Development of novel therapeutic strategies to tackle multidrug-resistant pathogens2011
- Author(s)
  Hayashi-Nishino, M., R. Nakashima, K. Sakurai, A. Yamaguchi, and K. Nishino
- Organizer
  France-Japan Workshop (Bio-inspired approaches: Micro- & Nano- Architectures, Materials & Imaging)
- Place of Presentation
  Bordeaux, France
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Immuno-electron tomography for elucidation of localization of the multidrug efflux pumps in Salmonella2011
- Author(s)
  Hayashi-Nishino, M., A. Yamaguchi, and K. Nishino
- Organizer
  7th Handai Nanoscience and Nanotechnology International Symposium
- Place of Presentation
  Osaka, Japan
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Role of AcrA on the function of the AcrD multidrug efflux pump in Salmonella enterica serovar Typhimurium2011
- Author(s)
  Yamasaki, S., S. Yamasaki, S. Nagasawa, M.Hayashi-Nishino, A. Yamaguchi, and K. Nishino
- Organizer
  4th Symposium on Antimicrobial Resistance in Animals and the Environment
- Place of Presentation
  Tours, France
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Small RNAによる細菌多剤耐性化メカニズムの解明2011
- Author(s)
  山崎聖司、西野-林美都子、山口明人、西野邦彦
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Immuno-electron tomography for elucidation of localization of the multidrug efflux pumps in Salmonella2011
- Author(s)
  Hayashi-Nishino, M., A. Yamaguchi, and K. Nishino
- Organizer
  7th Handai Nanoscience and Nanotechnology International Symposium(招待講演)
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Development of novel therapeutic strategies to tackle multidrug-resistant pathogens.2011
- Author(s)
  Nishino, K., et al.
- Organizer
  The American Association for the Advancement of Science (AAAS) 2011 Annual Meeting
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2011-02-20
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] サルモネラ薬物排出トランスポーターの生理機能解析2011
- Author(s)
  大野愛子、尾島学、西野美都子、山口明人、西野邦彦
- Organizer
  第33回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  岡山
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium2011
- Author(s)
  Yamasaki, S., S. Nagasawa, M. Hayashi-Nishino, A. Yamaguchi, K. Nishino
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-23790085
[Presentation] Electron Tomography Revealed the Endoplasmic Reticulum as a Source of Autophagosomal Membranes2010
- Author(s)
  西野美都子
- Organizer
  ASM American Society for Microbiology 110th General Meeting
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2010-05-24
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] Electron Tomography Revealed a Subdomain of the Endoplasmic Reticulum as a Cradle for Autophagosome Formation2010
- Author(s)
 Hayashi-Nishino, M., et al.
- Organizer
 The 13^<th> Sanken International Symposium
- Place of Presentation
 Osaka
- Year and Date
 2010-01-18
- Data Source
 KAKENHI-PROJECT-21890122
[Presentation] Role of the RNA Chaperon Hfq in Multidrug Resistance of Escherichia coli2010
- Author(s)
  Nishino, K., et al.
- Organizer
  NSMS & NZSBMB Joint Meeting
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] Electron Tomography Revealed a Subdomain of the Endoplasmic Reticulum as a Cradle for Autophagosome Formation2010
- Author(s)
  西野美都子
- Organizer
  The 13th Sanken International Symposium
- Place of Presentation
  Osaka
- Year and Date
  2010-01-18
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] Electron Tomography Revealed a Subdomain of the Endoplasmic Reticulum as a Cradle for Autophagosome Formation2009
- Author(s)
  西野美都子
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪大学(大阪府)
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] Autophagy and the Endoplasmic Reticulum2009
- Author(s)
  西野美都子
- Organizer
  5th International Symposium on Autophagy Meeting
- Place of Presentation
  Otsu, Shiga(招待講演)
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] 電子線トモグラフィーを用いたダイナミン1ノックアウトマウスの神経終末におけるエンドサイトーシス中間体の解析2009
- Author(s)
  西野美都子, 他
- Organizer
  第52回日本神経化学会大会シンポジウム
- Place of Presentation
  群馬
- Year and Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] Electron Tomography Revealed a Subdomain of the Endoplasmic Reticulum as a Cradle for Autophagosome Formation2009
- Author(s)
  西野美都子, 他
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] Autophagy and the Endoplasmic Reticulum2009
- Author(s)
 Hayashi-Nishino, M., et al.
- Organizer
 5^<th> International Symposium on Autophagy Meeting
- Place of Presentation
 Otsu, Shiga
- Year and Date
 2009-09-25
- Data Source
 KAKENHI-PROJECT-21890122
[Presentation] 電子線トモグラフィーを用いたダイナミン1ノックアウトマウスの神経終末におけるエンドサイトーシス中間体の解析2009
- Author(s)
  西野美都子
- Organizer
  第52回日本神経化学会大会シンポジウム
- Place of Presentation
  伊香保温泉ホテル天坊(群馬県)(招待講演)
- Year and Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] 電子線トモグラフィーにより見いだされた、オートファゴソームを形成する"ゆりかご"としての小胞体サブドメイン2009
- Author(s)
  西野美都子
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] 電子線トモグラフィーにより見いだされた、オートファゴソームを形成する"ゆりかご"としての小胞体サブドメイン2009
- Author(s)
  西野美都子, 他
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] 電子線トモグラフィーにより見いだされた、オートファゴソームを形成する"ゆりかご"としての小胞体サブドメイン、視る生物学42009
- Author(s)
  西野美都子
- Organizer
  進化するイメージング
- Place of Presentation
  奈良先端科学技術大学院大学(奈良県)(招待講演)
- Year and Date
  2009-11-24
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] 電子線トモグラフィーにより見いだされた、オートファゴソームを形成する"ゆりかご"としての小胞体サブドメイン2009
- Author(s)
  西野美都子
- Organizer
  視る生物学4-進化するイメージング-
- Place of Presentation
  奈良
- Year and Date
  2009-11-24
- Data Source
  KAKENHI-PROJECT-21890122
[Presentation] サルモネラ薬剤自然抵抗性における薬剤排出ポンプとLPSの関係
- Author(s)
  山崎聖司、西野美都子、西野邦彦
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  岐阜
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460524
[Presentation] 電子線トモグラフィーによる細胞小器官の3D解析
- Author(s)
  西野美都子
- Organizer
  第37回組織細胞化学講習会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23790085

1. 西野邦彦 (30432438)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. Harada Akihiro (40251441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 木下タロウ (10153165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 青木工太 (90447532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 田口厚志 (20908686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. MASUDA Junko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. MORITA Yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 中村宜督

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 山崎聖司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. ZWAMA MARTIJN

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 松本真司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishino Mitsuko 西野 美都子

NISHINO Mitsuko 西野 美都子

Research Projects

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Co-Researchers

Dynamic analysis of the formation mechanism of the xenobiotic efflux complexs

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Biometric study of drug resistant bacteria

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AIによる多剤耐性菌モルフォミクスとバイオインフォマティクスの融合研究Principal Investigator

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Discrimination of multi-drug resistant bacteria by machine learning.Principal Investigator

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Significance of polarized transport zones in organelles during polarized transport in epithelial cells

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Regulation of bacterial pathogenicity by the ABC transporterPrincipal Investigator

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Inhibitor development and the functional elucidation of the drug efflux transporter which participates in multidrug resistance and pathogenic revelationPrincipal Investigator

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Study on defense mechanisms of bacteria and host cells in infection.Principal Investigator

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[Book] 組織細胞化学技術プロトコール 組織細胞化学の挑戦 -臨床応用研究への飛躍-見る!-電子顕微鏡の基礎と応用- 「電子線トモグラフィーによる細胞小器官の3D解析」2012

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[Book] オートファジー「電子顕微鏡を用いたオートファジー解析」2012

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[Book] オートファジー「電子顕微鏡を用いたオートファジー解析」2012

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[Book] 組織細胞化学技術プロトコール 組織細胞化学の挑戦 -臨床応用研究への飛躍- 見る！-電子顕微鏡の基礎と応用-「電子線トモグラフィーによる細胞小器官の3D解析」2012

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[Journal Article] Major primary bile salts repress Salmonella enterica serovar Typhimurium invasiveness partly via the efflux regulatory locus ramRA2024

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[Journal Article] Changes in the expression of <i>mexB</i>, <i>mexY</i>, and <i>oprD</i> in clinical <i>Pseudomonas aeruginosa</i> isolates2024

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Nishino Mitsuko 西野美都子

NISHINO Mitsuko 西野美都子

[Book] 組織細胞化学技術プロトコール組織細胞化学の挑戦 -臨床応用研究への飛躍-見る!-電子顕微鏡の基礎と応用- 「電子線トモグラフィーによる細胞小器官の3D解析」2012

[Book] 組織細胞化学技術プロトコール組織細胞化学の挑戦 -臨床応用研究への飛躍- 見る！-電子顕微鏡の基礎と応用-「電子線トモグラフィーによる細胞小器官の3D解析」2012