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NAGATOISHI Satoru  長門石 曉

… Alternative Names

Nagatoishi Satoru  長門石 暁

長門石 暁  ナガトイシ サトル

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Researcher Number 30550248
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-0794-3963
Affiliation (Current) 2025: 東京大学, 大学院工学系研究科(工学部), 准教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 東京大学, 大学院工学系研究科(工学部), 准教授
2016 – 2022: 東京大学, 医科学研究所, 特任准教授
2017: 東京大学, 医科学研究所, 助教
2016: 東京大学, 大学院工学系研究科(工学部), 助教
2015: 東京大学, 大学院工学系研究科, 助教 … More
2013 – 2015: 東京大学, 工学(系)研究科(研究院), 助教
2012: 東京大学, 医科学研究所, 助教
2010 – 2011: 甲南大学, 先端生命工学研究所, 助教 Less
Review Section/Research Field
Principal Investigator
Basic Section 37010:Bio-related chemistry / Bio-related chemistry / Chemistry related to living body
Except Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Biofunction/Bioprocess / Basic Section 35010:Polymer chemistry-related / Basic Section 27040:Biofunction and bioprocess engineering-related / Complex systems / Functional biochemistry / Biomolecular chemistry / Pathology, Infection/Immunology, and related fields / Tumor therapeutics / Chemistry related to living body
Keywords
Principal Investigator
熱力学 / リガンド / 速度論 / 蛋白質 / 相互作用 / 蛋白質-蛋白質間相互作用 / 蛋白質-蛋白質相互作用 / 蛋白質エンジニアリング / 物理化学 / 低分子 … More / 低分子創薬 / 阻害剤 / 活性化エネルギー / 薬剤 / 溶媒和 / 物理化学解析 / 天然変性蛋白質 / 核酸 / 天然変性型蛋白質 … More
Except Principal Investigator
抗体 / タンパク質相互作用 / 物理化学 / 蛋白質 / 骨髄系腫瘍 / 薬学 / 分子認識 / 熱力学 / Split-GFP / Cas13 / NONO / 核酸医薬 / CRISPR/Cas13 / NEAT1 / lncRNA / 分子ダイナミクス / ひずみエネルギー / 非線形粘弾性 / 過渡的網目 / レオロジー / ダイナミクス / 蛋白質エンジニアリング / 分子動力学計算 / 金属イオン / CDR / フラクチュエーション / ペプチド / 計算科学 / 受容体 / 抗原 / ASXL1 / EVI1 / CBFB / RUNX1 / エピゲノム因子 / タンパク質間相互作用 / エピゲノム制御因子 / 転写因子 / 物理化学評価 / 構造基盤 / 発動分子 / 神経科学 / シグナル伝達 / 神経筋疾患 / 神経筋シナプス / コンピュータシミュレーション / スプライシング / ヒストン / 血管内皮細胞 / オルタナティブスプライシング / パターン認識受容体 / 自然免疫 / 細胞周期 / RNAプロセッシング / ペントラキシン / ヒストン障害 / 敗血症 / 蛋白質間相互作用 / 遷移状態 / 創薬 / 速度論 / 阻害剤 / 低分子 / 蛋白質-蛋白質相互作用 / 分子標的薬 / 分子間相互作用 / 菌種特異的増殖阻害剤 / 細菌感染症 / 機能阻害 / 単分子抗体 / 鉄取り込み / スクリーニング / 低分子化合物 / 増殖阻害薬 / ヘム鉄 / Shr / 鉄獲得系 / A群レンサ球菌 / 癌 / トランスレーショナルリサーチ / 遺伝子 / タンパク質 / 創薬スクリーニング系 / がん幹細胞性 / 生物・生体工学 / 低分子スクリーニング / 相互作用 / フラグメントスクリーニング / 熱力学解析 / 低分子創薬 / 分子クラウディング / タンパク質構造 / 熱力学的安定性 / mRNA高次構造 / 翻訳速度 / Protein Folding Codon Less
  • Research Projects

    (15 results)
  • Research Products

    (399 results)
  • Co-Researchers

    (52 People)
  •  過渡的網目の非線形粘弾性解析: ひずみエネルギー密度関数解析とその分子論の解明

    • Principal Investigator
      片島 拓弥
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 35010:Polymer chemistry-related
    • Research Institution
      The University of Tokyo
  •  Identification of tumor driver lncRNAs in myeloid tumors and development of lncRNA-targeting therapies

    • Principal Investigator
      合山 進
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      The University of Tokyo
  •  Elucidation and Control of Local Fractions in Protein Engineering

    • Principal Investigator
      Tsumoto Kouhei
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 27040:Biofunction and bioprocess engineering-related
    • Research Institution
      The University of Tokyo
  •  Targeting transcription and epigenetic factors through modulation of protein-protein interactions

    • Principal Investigator
      Goyama Susumu
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      The University of Tokyo
  •  Elucidation of the weak interaction-triggered system of proteins and its design proposalPrincipal Investigator

    • Principal Investigator
      NAGATOISHI Satoru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  Structural basis and physico-chemical evaluation for rational design and theoretical calculation of molecular engine

    • Principal Investigator
      Murata Takeshi
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Chiba University
  •  Development of species-specific anti-bacterial therapeutic agents based on molecular interaction

    • Principal Investigator
      NAKAGAWA ICHIRO
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Pathology, Infection/Immunology, and related fields
    • Research Institution
      Kyoto University
  •  Functional analysis and development for anti-tumor compounds targeted PRDM14 relating to cancer stemness based on protein-protein interaction

    • Principal Investigator
      Taniguchi Hiroaki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      The University of Tokyo
  •  Screening and design of ligands regulating the process of protein-protein interactions based on biophysical approaches

    • Principal Investigator
      Tsumoto Kouhei
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      The University of Tokyo
  •  Design of protein binders based on the activation energy of interactionPrincipal Investigator

    • Principal Investigator
      NAGATOISHI SATORU
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  Elucidation of the mechanism underlying the formation of neuromuscular synapse

    • Principal Investigator
      Ueta Ryo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  Ligand discovery based on biophysical analyses

    • Principal Investigator
      Tsumoto Kouhei
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      The University of Tokyo
  •  Dynamics of Molecular Pattern Recognition in Protein Interaction

    • Principal Investigator
      HAMAKUBO TAKAO
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      The University of Tokyo
  •  Physicochemical studies of YB-1 functions and structuresPrincipal Investigator

    • Principal Investigator
      NAGATOISHI Satoru
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Chemistry related to living body
    • Research Institution
      The University of Tokyo
  •  Analyses of Protein Folding Codon affecting protein functions

    • Principal Investigator
      SUGIMOTO Naoki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Chemistry related to living body
    • Research Institution
      Konan University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Other

  • [Book] 創薬研究のためのスクリーニング学実践テキスト2022

    • Author(s)
      (分担)長門石曉,津本浩平、(編)スクリーニング学研究会
    • Total Pages
      374
    • Publisher
      羊土社
    • ISBN
      9784758122580
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Book] 医薬品開発のための分光法2022

    • Author(s)
      津本 浩平、長門石 曉、半沢 宏之
    • Total Pages
      272
    • Publisher
      講談社
    • ISBN
      9784065295823
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Book] 医薬品開発のための分光法2022

    • Author(s)
      津本 浩平、長門石 曉、半沢 宏之
    • Total Pages
      272
    • Publisher
      講談社
    • ISBN
      9784065295823
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Book] 創薬研究のための相互作用解析パーフェクト2021

    • Author(s)
      長門石曉、津本浩平
    • Total Pages
      368
    • Publisher
      羊土社
    • ISBN
      4758122563
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Book] 熱量測定・熱分析ハンドブック 第3版2020

    • Author(s)
      長門石曉, 津本浩平
    • Total Pages
      363
    • Publisher
      日本熱測定学会
    • ISBN
      9784621305072
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Book] 膜タンパク質工学ハンドブック2020

    • Author(s)
      由井杏奈, 妹尾暁暢, 長門石曉, 津本浩平
    • Total Pages
      624
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784860435370
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Book] 表面プラズモン共鳴(SPR)法を用いた蛋白質に結合する低分子リガンドスクリーニング2020

    • Author(s)
      妹尾 暁暢、長門石 曉、津本 浩平
    • Total Pages
      11
    • Publisher
      蛋白質科学会アーカイブ
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Book] 機器分析ハンドブック 2 高分子・分離分析編2020

    • Author(s)
      中木戸誠, 長門石曉, 津本浩平
    • Total Pages
      192
    • Publisher
      化学同人
    • ISBN
      9784759820225
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Book] 材料創製を指向したタンパク質相互作用解析, 高分子, 68巻3月号, 126-1272019

    • Author(s)
      長門石曉, 中木戸誠, 津本浩平
    • Total Pages
      2
    • Publisher
      高分子学会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Book] 材料創製を指向したタンパク質相互作用解析2019

    • Author(s)
      長門石 暁、中木戸 誠、津本 浩平
    • Total Pages
      45
    • Publisher
      高分子学会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Book] 第19章 抗体医薬の基礎物性評価 医薬品原薬の結晶化と物性評価:その最先端技術と評価の実際2019

    • Author(s)
      津本浩平, 長門石曉
    • Total Pages
      10
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Book] 第19章 抗体医薬の基礎物性評価2019

    • Author(s)
      津本 浩平、長門石 暁
    • Total Pages
      260
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Book] 材料創製を指向したタンパク質相互作用解析 高分子, 68巻3月号2019

    • Author(s)
      長門石曉, 中木戸誠, 津本浩平
    • Total Pages
      2
    • Publisher
      高分子学会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Book] 薬学雑誌, 138(8), 1033-10412018

    • Author(s)
      長門石曉, Jose M. M. Caaveiro, 津本浩平 次世代の低分子創薬を拓くタンパク質-低分子間相互作用の物理化学的解析
    • Total Pages
      9
    • Publisher
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Book] タンパク質相互作用の創薬-物理化学を介して 生体の科学, Vol.69, No.4, 349-3532018

    • Author(s)
      長門石曉, 津本浩平
    • Total Pages
      5
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Book] 第19章 抗体医薬の基礎物性評価, 医薬品原薬の結晶化と物性評価:その最先端技術と評価の実際2018

    • Author(s)
      津本浩平, 長門石曉
    • Total Pages
      10
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Book] タンパク質相互作用の創薬-物理化学を介して, 生体の科学, Vol.69, No.4, 349-3532018

    • Author(s)
      長門石曉, 津本浩平
    • Total Pages
      5
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Book] バイオ医薬品の分析のコツ 品質評価のための基礎と応用(第7回)タンパク質の分子間相互作用 PHARM TECH JAPAN 2018年2月号 Vol.34 No.2, 339-3452018

    • Author(s)
      津本浩平, 長門石曉, 中木戸誠, 黒田大祐
    • Total Pages
      7
    • Publisher
      株式会社じほう
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Book] CSJカレントビュー 医療・診断・創薬の化学 医療応用のための物理化学2017

    • Author(s)
      津本浩平、長門石曉(分担執筆)
    • Total Pages
      6
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Book] CSJカレントビュー 医療・診断・創薬の化学 医療応用のための物理化学2017

    • Author(s)
      津本浩平、長門石曉
    • Total Pages
      6
    • Publisher
      化学同人
    • ISBN
      9784759813845
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Book] バイオサイエンスとインダストリー「物理化学的解析技術を利用したリガンドスクリーニング」2017

    • Author(s)
      長門石 曉、津本 浩平
    • Total Pages
      5
    • Publisher
      バイオインダストリー協会
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Book] 生体分子化学 8章 酵素2017

    • Author(s)
      長門石曉、津本浩平(分担執筆)
    • Total Pages
      27
    • Publisher
      講談社
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Book] 生体分子化学「8章酵素」2017

    • Author(s)
      長門石 曉、津本 浩平(分担執筆)
    • Total Pages
      307
    • Publisher
      講談社
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Book] 生体分子化学 8章 酵素2017

    • Author(s)
      長門石曉、津本浩平(分担執筆)
    • Total Pages
      27
    • Publisher
      講談社
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Book] ファルマシア「結合熱力学プロファイリングによる創薬」2015

    • Author(s)
      長門石 曉・楠﨑佑子・津本 浩平
    • Total Pages
      5
    • Publisher
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Book] 実験医学 研究成果を薬につなげるアカデミア創薬の戦略と実例:化合物の“質”を評価する新しいスクリーニング系2014

    • Author(s)
      長門石曉、津本浩平
    • Total Pages
      220
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Book] 技術レポート2023:物理化学的スクリーニング技術による創薬戦略と展望2013

    • Author(s)
      長門石曉、津本浩平
    • Total Pages
      324
    • Publisher
      日本能率協会総合研究所
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Book] 「等温滴定型カロリメトリー」ぶんせき2012

    • Author(s)
      長門石曉・津本浩平
    • Publisher
      日本分析化学会
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Book] 等温滴定型カロリメトリー2012

    • Author(s)
      長門石 曉、津本 浩平
    • Total Pages
      63
    • Publisher
      ぶんせき (日本分析化学会)
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Journal Article] In vitro validation of chromogenic substrate assay for evaluation of surrogate FVIII-activity of emicizumab2023

    • Author(s)
      Yamaguchi Tomoko、Shinozawa Keiko、Nagatoishi Satoru、Mitsuhashi Ayano、Bingo Masato、Inaba Hiroshi、Amano Kagehiro、Tsumoto Kohei、Kinai Ei
    • Journal Title

      Thrombosis Research

      Volume: 222 Pages: 131-139

    • DOI

      10.1016/j.thromres.2023.01.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Journal Article] Agarose native gel electrophoresis analysis of thermal aggregation controlled by Hofmeister series2023

    • Author(s)
      Tomioka Yui、Sato Ryo、Takahashi Ryo、Nagatoishi Satoru、Shiba Kohei、Tsumoto Kouhei、Arakawa Tsutomu、Akuta Teruo
    • Journal Title

      Biophysical Chemistry

      Volume: 296 Pages: 106977-106977

    • DOI

      10.1016/j.bpc.2023.106977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Journal Article] Development of an Outward Proton Pumping Rhodopsin with a New Record in Thermostability by Means of Amino Acid Mutations2022

    • Author(s)
      Yasuda Satoshi、Akiyama Tomoki、Kojima Keiichi、Ueta Tetsuya、Hayashi Tomohiko、Ogasawara Satoshi、Nagatoishi Satoru、Tsumoto Kouhei、Kunishima Naoki、Sudo Yuki、Kinoshita Masahiro、Murata Takeshi
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 126 Issue: 5 Pages: 1004-1015

    • DOI

      10.1021/acs.jpcb.1c08684

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K14674, KAKENHI-PLANNED-18H05425, KAKENHI-PUBLICLY-21H00404, KAKENHI-PROJECT-21H02446, KAKENHI-PROJECT-20K21482, KAKENHI-PROJECT-21K15054, KAKENHI-PROJECT-20H02531
  • [Journal Article] Analysis of bovine serum albumin unfolding in the absence and presence of ATP by SYPRO Orange staining of agarose native gel electrophoresis2022

    • Author(s)
      Tomioka Yui、Nakagawa Masataka、Sakuma Chiaki、Kurosawa Yasunori、Nagatoishi Satoru、Tsumoto Kouhei、Arakawa Tsutomu、Akuta Teruo
    • Journal Title

      Analytical Biochemistry

      Volume: 654 Pages: 114817-114817

    • DOI

      10.1016/j.ab.2022.114817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Journal Article] Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus.2022

    • Author(s)
      Valenciano-Bellido Sandra、Caaveiro Jose M.M.、Morante Koldo、Sushko Tatyana、Nakakido Makoto、Nagatoishi Satoru、Tsumoto Kouhei
    • Journal Title

      Journal of Biological Chemistry

      Volume: - Issue: 6 Pages: 101995-101995

    • DOI

      10.1016/j.jbc.2022.101995

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-18H05425
  • [Journal Article] Experimental Comparison of Bond Lifetime and Viscoelastic Relaxation in Transient Networks with Well-Controlled Structures2022

    • Author(s)
      Katashima Takuya、Kudo Ryota、Naito Mitsuru、Nagatoishi Satoru、Miyata Kanjiro、Chung Ung-il、Tsumoto Kouhei、Sakai Takamasa
    • Journal Title

      ACS Macro Letters

      Volume: 11 Issue: 6 Pages: 753-759

    • DOI

      10.1021/acsmacrolett.2c00152

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-20H05733, KAKENHI-PROJECT-21H04688, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20K15338
  • [Journal Article] Nucleic acid-triggered tumoral immunity propagates pH‐selective therapeutic antibodies through tumor‐driven epitope spreading2022

    • Author(s)
      Furuya G, Katoh H, Atsumi S, Hashimoto I, Komura D, Hatanaka R, Senga S, Hayashi S, Akita S, Matsumura H, Miura A, Mita H, Nakakido M, Nagatoishi S, Sugiyama A, Suzuki R, Konishi H, Yamamoto A, Abe H, Hiraoka N, Aoki K, Kato Y, Seto Y, Yoshimura C, Miyadera K, Tsumoto K, Ushiku T, Ishikawa S
    • Journal Title

      Cancer Science

      Volume: 114 Issue: 1 Pages: 321-338

    • DOI

      10.1111/cas.15596

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10074, KAKENHI-PROJECT-22K09929, KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-20H02531
  • [Journal Article] Biophysical Characterization of the Contribution of the Fab Region to the IgG-FcγRIIIa Interaction2022

    • Author(s)
      Kosuge Hirofumi、Nagatoishi Satoru、Kiyoshi Masato、Ishii-Watabe Akiko、Terao Yosuke、Ide Teruhiko、Tsumoto Kouhei
    • Journal Title

      Biochemistry

      Volume: 62 Issue: 2 Pages: 262-269

    • DOI

      10.1021/acs.biochem.1c00832

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-22KJ0925, KAKENHI-PLANNED-18H05425, KAKENHI-PLANNED-19H05766
  • [Journal Article] Ladder observation of bovine serum albumin by high resolution agarose native gel electrophoresis2022

    • Author(s)
      Tomioka Yui、Nakagawa Masataka、Sakuma Chiaki、Nagatoishi Satoru、Tsumoto Kouhei、Arakawa Tsutomu、Akuta Teruo
    • Journal Title

      International Journal of Biological Macromolecules

      Volume: 215 Pages: 512-520

    • DOI

      10.1016/j.ijbiomac.2022.06.118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Journal Article] An integrated computational pipeline for designing high-affinity nanobodies with expanded genetic codes2021

    • Author(s)
      Aditya K Padhi, Ashutosh Kumar, Ken-ichi Haruna, Haruna Sato, Hiroko Tamura, Satoru Nagatoishi, Kouhei Tsumoto, Atushi Yamaguchi, Fumie Iraha, Mihoko Takahashi, Kensaku Sakamoto, Kam Y J Zhang
    • Journal Title

      Briefings in Bioinformatics

      Volume: 22 Issue: 6

    • DOI

      10.1093/bib/bbab338

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02416, KAKENHI-PROJECT-20H02531
  • [Journal Article] Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate2021

    • Author(s)
      Ota Tomoki、Senoo Akinobu、Shirakawa Masumi、Nonaka Hiroshi、Saito Yutaro、Ito Sho、Ueno Go、Nagatoishi Satoru、Tsumoto Kouhei、Sando Shinsuke
    • Journal Title

      iScience

      Volume: 24 Issue: 2 Pages: 102036-102036

    • DOI

      10.1016/j.isci.2021.102036

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19J14451
  • [Journal Article] Structural and thermodynamical insights into the binding and inhibition of FIH-1 by the N-terminal disordered region of Mint3.2021

    • Author(s)
      Ten T, Nagatoishi S, Maeda R, Hoshino M, Nakayama Y, Seiki M, Sakamoto T, Tsumoto K.
    • Journal Title

      J Biol Chem.

      Volume: 297 Issue: 5 Pages: 101304-101304

    • DOI

      10.1016/j.jbc.2021.101304

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion2021

    • Author(s)
      Senoo Akinobu、Ito Sho、Nagatoishi Satoru、Saito Yutaro、Ueno Go、Kuroda Daisuke、Yoshida Kouhei、Tashima Takumi、Kudo Shota、Sando Shinsuke、Tsumoto Kouhei
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 1041-1041

    • DOI

      10.1038/s42003-021-02575-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-19H03522, KAKENHI-PLANNED-19H05766
  • [Journal Article] Anion solvation enhanced by positive supercharging mutations preserves thermal stability of an antibody in a wide pH range2021

    • Author(s)
      Kasahara Keisuke、Kuroda Daisuke、Tanabe Aki、Kawade Raiji、Nagatoishi Satoru、Tsumoto Kouhei
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 563 Pages: 54-59

    • DOI

      10.1016/j.bbrc.2021.05.053

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H04202
  • [Journal Article] Elaboration of Non-naturally Occurring Helical Tripeptides as p53–MDM2/MDMX Interaction Inhibitors2021

    • Author(s)
      Su Aoze、Tabata Yuko、Aoki Kiyono、Sada Akane、Ohki Rieko、Nagatoishi Satoru、Tsumoto Kouhei、Wang Siyuan、Otani Yuko、Ohwada Tomohiko
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 69 Issue: 7 Pages: 681-692

    • DOI

      10.1248/cpb.c21-00238

    • NAID

      130008060029

    • ISSN
      0009-2363, 1347-5223
    • Year and Date
      2021-07-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07605, KAKENHI-PROJECT-18H02552, KAKENHI-PROJECT-20H02531
  • [Journal Article] Mechanism of dimerization and structural features of human LI-cadherin2021

    • Author(s)
      Yui Anna、Caaveiro Jose M.M.、Kuroda Daisuke、Nakakido Makoto、Nagatoishi Satoru、Goda Shuichiro、Maruno Takahiro、Uchiyama Susumu、Tsumoto Kouhei
    • Journal Title

      Journal of Biological Chemistry

      Volume: 297 Issue: 3 Pages: 101054-101054

    • DOI

      10.1016/j.jbc.2021.101054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival2021

    • Author(s)
      Nishinaga Megumi、Sugimoto Hiroshi、Nishitani Yudai、Nagai Seina、Nagatoishi Satoru、Muraki Norifumi、Tosha Takehiko、Tsumoto Kouhei、Aono Shigetoshi、Shiro Yoshitsugu、Sawai Hitomi
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 467-467

    • DOI

      10.1038/s42003-021-01987-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PLANNED-19H05762, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03093, KAKENHI-PROJECT-18K05321, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-21H02064, KAKENHI-PROJECT-21H02421, KAKENHI-PROJECT-20K06517, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF12021

    • Author(s)
      Kori Satomi、Shibahashi Yuki、Ekimoto Toru、Nishiyama Atsuya、Yoshimi Sae、Yamaguchi Kosuke、Nagatoishi Satoru、Ohta Masateru、Tsumoto Kouhei、Nakanishi Makoto、Defossez Pierre-Antoine、Ikeguchi Mitsunori、Arita Kyohei
    • Journal Title

      Bioorg Med Chem

      Volume: 52 Pages: 116500-116500

    • DOI

      10.1016/j.bmc.2021.116500

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-18H05425, KAKENHI-PLANNED-18H05426, KAKENHI-PUBLICLY-21H00272, KAKENHI-PROJECT-19H03153, KAKENHI-PROJECT-19J22030, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05741
  • [Journal Article] A glutamine sensor that directly activates TORC12021

    • Author(s)
      Tanigawa Mirai、Yamamoto Katsuyoshi、Nagatoishi Satoru、Nagata Koji、Noshiro Daisuke、Noda Nobuo N.、Tsumoto Kouhei、Maeda Tatsuya
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 1093-1093

    • DOI

      10.1038/s42003-021-02625-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-18H02151, KAKENHI-PROJECT-20H03251, KAKENHI-PROJECT-20K06555, KAKENHI-PROJECT-19K16344, KAKENHI-PROJECT-20H02531
  • [Journal Article] B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice2021

    • Author(s)
      Lee MSL, Inoue T, Ise W, Matsuo-Dapaah J, Wing JB, Temizoz B, Kobiyama K, Hayashi T, Patil A, Sakaguchi S, Simon AK, Bezbradica JS, Nagatoishi S, Tsumoto K, Inoue J, Akira S, Kurosaki T, Ishii KJ, Coban C
    • Journal Title

      Journal of Experimental Medicine

      Volume: 219 Issue: 2

    • DOI

      10.1084/jem.20211336

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02749, KAKENHI-PROJECT-20H03503, KAKENHI-PROJECT-20H02531
  • [Journal Article] Thermodynamic Dissection of Potency and Selectivity of Cytosolic Hsp90 Inhibitors2021

    • Author(s)
      Yoshimura Chihoko、Nagatoishi Satoru、Kuroda Daisuke、Kodama Yasuo、Uno Takao、Kitade Makoto、Chong-Takata Khoontee、Oshiumi Hiromi、Muraoka Hiromi、Yamashita Satoshi、Kawai Yuichi、Ohkubo Shuichi、Tsumoto Kouhei
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 64 Issue: 5 Pages: 2669-2677

    • DOI

      10.1021/acs.jmedchem.0c01715

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells2021

    • Author(s)
      Eguchi Akihiro、Ueki Ayaka、Hoshiyama Junya、Kuwata Keiko、Chikaoka Yoko、Kawamura Takeshi、Nagatoishi Satoru、Tsumoto Kouhei、Ueki Ryosuke、Sando Shinsuke
    • Journal Title

      JACS Au

      Volume: n/a Issue: 5 Pages: 578-585

    • DOI

      10.1021/jacsau.0c00121

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K15693, KAKENHI-PROJECT-20H02531
  • [Journal Article] The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis2021

    • Author(s)
      Sekiya Motohiro、Kainoh Kenta、Sugasawa Takehito、Yoshino Ryunosuke、Hirokawa Takatsugu、Tokiwa Hiroaki、Nakano Shogo、Nagatoishi Satoru、Tsumoto Kouhei、Takeuchi Yoshinori、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 1-19

    • DOI

      10.1038/s41467-021-26638-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07272, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-20H02531
  • [Journal Article] Development of biparatopic bispecific antibody possessing tetravalent scFv-Fc capable of binding to ROBO1 expressed in hepatocellular carcinoma cells2021

    • Author(s)
      Watanabe Yuji、Tanabe Aki、Hamakubo Takao、Nagatoishi Satoru、Tsumoto Kouhei
    • Journal Title

      The Journal of Biochemistry

      Volume: 170 Issue: 2 Pages: 307-315

    • DOI

      10.1093/jb/mvab049

    • NAID

      40022722450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR2021

    • Author(s)
      Kosuge Hirofumi、Nakakido Makoto、Nagatoishi Satoru、Fukuda Tetsuya、Bando Yasuhiko、Ohnuma Shin-ichi、Tsumoto Kouhei
    • Journal Title

      Journal of Biological Chemistry

      Volume: 296 Pages: 100278-100278

    • DOI

      10.1016/j.jbc.2021.100278

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] Electrostatic-triggered exothermic antibody adsorption to the cellulose nanoparticles2021

    • Author(s)
      Murakami Keisuke、Nagatoishi Satoru、Kasahara Keisuke、Nagai Hirokazu、Sasajima Yoshiyuki、Sasaki Ryo、Tsumoto Kouhei
    • Journal Title

      Analytical Biochemistry

      Volume: 632 Pages: 114337-114337

    • DOI

      10.1016/j.ab.2021.114337

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] Structural Basis for the Binding Mechanism of Human Serum Albumin Complexed with Cyclic Peptide Dalbavancin2020

    • Author(s)
      Ito Sho、Senoo Akinobu、Nagatoishi Satoru、Ohue Masahito、Yamamoto Masaki、Tsumoto Kouhei、Wakui Naoki
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 63 Issue: 22 Pages: 14045-14053

    • DOI

      10.1021/acs.jmedchem.0c01578

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K19926, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19J14451
  • [Journal Article] Polymeric Nanocarriers with Controlled Chain Flexibility Boost mRNA Delivery In Vivo through Enhanced Structural Fastening2020

    • Author(s)
      Miyazaki Takuya、Uchida Satoshi、Nagatoishi Satoru、Koji Kyoko、Hong Taehun、Fukushima Shigeto、Tsumoto Kouhei、Ishihara Kazuhiko、Kataoka Kazunori、Cabral Horacio
    • Journal Title

      Advanced Healthcare Materials

      Volume: 9 Issue: 16 Pages: 2000538-2000538

    • DOI

      10.1002/adhm.202000538

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-20H04524
  • [Journal Article] Discovery of chemical probes that suppress Wnt/β-catenin signaling through high-throughput screening.2020

    • Author(s)
      Yamaguchi K, Nagatoishi S, Tsumoto K, Furukawa Y.
    • Journal Title

      Cancer Sci.

      Volume: 111 Issue: 3 Pages: 783-794

    • DOI

      10.1111/cas.14297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K07214
  • [Journal Article] Highly sensitive HPLC analysis and biophysical characterization of N‐glycans of IgG‐Fc domain in comparison between CHO and 293 cells using FcγRIIIa ligand2020

    • Author(s)
      Kosuge Hirofumi、Nagatoishi Satoru、Kiyoshi Masato、Ishii‐Watabe Akiko、Tanaka Toru、Terao Yosuke、Oe Seigo、Ide Teruhiko、Tsumoto Kouhei
    • Journal Title

      Biotechnology Progress

      Volume: 36 Issue: 6

    • DOI

      10.1002/btpr.3016

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] Per-Residue Program of Multiple Backbone Dihedral Angles of β-Peptoids via Backbone Substitutions2020

    • Author(s)
      Jumpei Morimoto, Jungyeon Kim, Daisuke Kuroda, Satoru Nagatoishi, Kouhei Tsumoto, Shinsuke Sando
    • Journal Title

      Journal of the American Chemical Society

      Volume: 142 Issue: 5 Pages: 2277-2284

    • DOI

      10.1021/jacs.9b10496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K15692, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H04202
  • [Journal Article] Technical capabilities and limitations of optical spectroscopy and calorimetry using water-miscible solvents: The case of dimethyl sulfoxide, acetonitrile and 1,4-dioxane.2020

    • Author(s)
      Hirano A, Nagatoishi S, Wada M, Tsumoto K, Maluf KN, Arakawa T.
    • Journal Title

      J Pharm Sci.

      Volume: 109 Pages: 524-531

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Journal Article] Methodology for Further Thermostabilization of an Intrinsically Thermostable Membrane Protein Using Amino Acid Mutations with Its Original Function Being Retained2020

    • Author(s)
      Yasuda Satoshi、Akiyama Tomoki、Nemoto Sayaka、Hayashi Tomohiko、Ueta Tetsuya、Kojima Keiichi、Tsukamoto Takashi、Nagatoishi Satoru、Tsumoto Kouhei、Sudo Yuki、Kinoshita Masahiro、Murata Takeshi
    • Journal Title

      Journal of Chemical Information and Modeling

      Volume: 60 Issue: 3 Pages: 1709-1716

    • DOI

      10.1021/acs.jcim.0c00063

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15099, KAKENHI-PROJECT-19K14674, KAKENHI-PROJECT-19K16090, KAKENHI-PLANNED-18H05425, KAKENHI-PUBLICLY-19H04727, KAKENHI-PUBLICLY-19H05396, KAKENHI-PROJECT-17H03663, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H02411
  • [Journal Article] Highly sensitive biomolecular interaction detection method using optical bound/free separation with grating-coupled surface plasmon field-enhanced fluorescence spectroscopy (GC-SPFS).2019

    • Author(s)
      Kaya T, Nagatoishi S, Nagae K, Nakamura Y, Tsumoto K.
    • Journal Title

      PLoS One.

      Volume: 14 Issue: 8 Pages: e0220578-e0220578

    • DOI

      10.1371/journal.pone.0220578

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Journal Article] A Peptoid with Ectended Shape in Water2019

    • Author(s)
      Morimoto J, Fukuda Y, Kuroda D, Watanabe T, Yoshida F, Asada M, Nakamura T, Senoo A, Nagatoishi S, Tsumoto K, *Sando S
    • Journal Title

      J Am Chem Soc.

      Volume: 141 Issue: 37 Pages: 14612-14623

    • DOI

      10.1021/jacs.9b04371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H04202
  • [Journal Article] An epitope‐directed antibody affinity maturation system utilizing mammalian cell survival as readout2019

    • Author(s)
      Eguchi Akihiro、Nakakido Makoto、Nagatoishi Satoru、Kuroda Daisuke、Tsumoto Kouhei、Nagamune Teruyuki、Kawahara Masahiro
    • Journal Title

      Biotechnology and Bioengineering

      Volume: 116 Issue: 7 Pages: 1742-1751

    • DOI

      10.1002/bit.26965

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H01792, KAKENHI-PROJECT-17K19007, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-17H06109
  • [Journal Article] Control of Protein Adsorption to Cyclo Olefin Polymer by the Hofmeister Effect.2019

    • Author(s)
      Fujita R, Nagatoishi S, Adachi S, Nishioka H, Ninomiya H, Kaya T, Takai M, Arakawa T, Tsumoto K.
    • Journal Title

      J Pharm Sci.

      Volume: 108 Issue: 5 Pages: 1686-1691

    • DOI

      10.1016/j.xphs.2018.12.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Journal Article] Phospholipid Membrane Fluidity Alters Ligand Binding Activity of a G Protein-Coupled Receptor by Shifting the Conformational Equilibrium.2019

    • Author(s)
      Yoshida K, Nagatoishi S, Kuroda D, Suzuki N, Murata T, Tsumoto K.
    • Journal Title

      Biochemistry

      Volume: 58(6) Issue: 6 Pages: 504-508

    • DOI

      10.1021/acs.biochem.8b01194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-16H04710
  • [Journal Article] Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction.2019

    • Author(s)
      Nonaka H, Nakanishi Y, Kuno S, Ota T, Mochidome K, Saito Y, Sugihara F, Takakusagi Y, Aoki I, Nagatoishi S, Tsumoto K, Sando S.
    • Journal Title

      Nat Commun.

      Volume: 10(1) Issue: 1 Pages: 876-876

    • DOI

      10.1038/s41467-019-08833-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
  • [Journal Article] Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction.2019

    • Author(s)
      Chigira T, Nagatoishi S, Takeda H, Yoshimaru T, Katagiri T, Tsumoto K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 518 Issue: 1 Pages: 183-189

    • DOI

      10.1016/j.bbrc.2019.08.028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06419, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K10551
  • [Journal Article] Structural features of methionine aminopeptidase2-active core peptide essential for binding with S100A42019

    • Author(s)
      Katagiri Naohiro、Nagatoishi Satoru、Tsumoto Kouhei、Endo Hideya
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 516 Issue: 4 Pages: 1123-1129

    • DOI

      10.1016/j.bbrc.2019.07.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-18H02082
  • [Journal Article] Exploring designability of electrostatic complementarity at an antigen-antibody interface directed by mutagenesis, biophysical analysis, and molecular dynamics simulations.2019

    • Author(s)
      Yoshida K, Kuroda D, Kiyoshi M, Nakakido M, Nagatoishi S, Soga S, Shirai H, Tsumoto K.
    • Journal Title

      Sci Rep.

      Volume: 9(1) Issue: 1 Pages: 4482-4482

    • DOI

      10.1038/s41598-019-40461-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17H06109
  • [Journal Article] Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface2019

    • Author(s)
      Yamashita Takefumi、Mizohata Eiichi、Nagatoishi Satoru、Watanabe Takahiro、Nakakido Makoto、Iwanari Hiroko、Mochizuki Yasuhiro、Nakayama Taisuke、Kado Yuji、Yokota Yuki、Matsumura Hiroyoshi、Kawamura Takeshi、Kodama Tatsuhiko、Hamakubo Takao、Inoue Tsuyoshi、Fujitani Hideaki、Tsumoto Kouhei
    • Journal Title

      Structure

      Volume: 27 Issue: 3 Pages: 519-527

    • DOI

      10.1016/j.str.2018.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06094, KAKENHI-PUBLICLY-17H05732, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17H06109
  • [Journal Article] Inhibition of homophilic dimerization and disruption of cell adhesion by P-cadherin-specific small molecules from SPR-based assays2018

    • Author(s)
      Senoo A, Nagatoishi S, Moberg A, Babol LN, Mitani T, Tashima T, Kudo S, Tsumoto K.
    • Journal Title

      Chemical Communications

      Volume: 54 Issue: 42 Pages: 5350-5353

    • DOI

      10.1039/c8cc01964a

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-16H04710
  • [Journal Article] Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery.2018

    • Author(s)
      Tanabe A, Nakano K, Nakakido M, Nagatoishi S, Tanaka Y, Tsumoto K, Uchimaru K, Watanabe T.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 496 Issue: 2 Pages: 614-620

    • DOI

      10.1016/j.bbrc.2018.01.051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H06693
  • [Journal Article] Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column2018

    • Author(s)
      Kiyoshi M, Caaveiro JMM, Tada M, Tamura H, Tanaka T, Terao Y, Morante K, Harazono A, Hashii N, Shibata H, Kuroda D, Nagatoishi S, Oe S, Ide T, Tsumoto K, Ishii-Watabe A
    • Journal Title

      Scientific Reports

      Volume: 8:3955 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41598-018-22199-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18113, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-15K06962
  • [Journal Article] A combination of 19 F NMR and surface plasmon resonance for site-specific hit selection and validation of fragment molecules that bind to the ATP-binding site of a kinase2018

    • Author(s)
      Nagatoishi S, Yamaguchi S, Katoh E, Kajita K, Yokotagawa T, Kanai S, Furuya T, Tsumoto K.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 26 Issue: 8 Pages: 1929-1938

    • DOI

      10.1016/j.bmc.2018.02.041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-16H04710
  • [Journal Article] A secondary RET mutation in the activation loop conferring resistance to vandetanib.2018

    • Author(s)
      Nakaoku T, Kohno T, Araki M, Niho S, Chauhan R, Knowles PP, Tsuchihara K, Matsumoto S, Shimada Y, Mimaki S, Ishii G, Ichikawa H, Nagatoishi S, Tsumoto K, Okuno Y, Yoh K, McDonald NQ, Goto K
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 625-625

    • DOI

      10.1038/s41467-018-02994-7

    • NAID

      120006406830

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15036, KAKENHI-PROJECT-16H02420
  • [Journal Article] PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.2018

    • Author(s)
      Moriya C, Taniguchi H, Nagatoishi S, Igarashi H, Tsumoto K, Imai K
    • Journal Title

      Cancer Sci.

      Volume: 109 Issue: 2 Pages: 373-383

    • DOI

      10.1111/cas.13458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710
  • [Journal Article] Development of drug discovery screening system by molecular interaction kinetics-mass spectrometry2018

    • Author(s)
      Obi N, Fukuda T, Nakayama N, Ervin J, Bando Y, Nishimura T, Nagatoishi S, Tsumoto K, Kawamura T.
    • Journal Title

      Rapid Communications in Mass Spectrometry

      Volume: 32 Issue: 8 Pages: 665-671

    • DOI

      10.1002/rcm.8083

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
  • [Journal Article] Biophysical Analysis of the Protein-Small Molecule Interactions to Develop Small Molecule Drug Discovery2018

    • Author(s)
      Nagatoishi S, Caaveiro JMM, Tsumoto K.
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 138 Issue: 8 Pages: 1033-1041

    • DOI

      10.1248/yakushi.17-00211-2

    • NAID

      130007429352

    • ISSN
      0031-6903, 1347-5231
    • Year and Date
      2018-08-01
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
  • [Journal Article] Thermodynamic and computational analyses reveal the functional roles of the galloyl group of tea catechins in molecular recognition.2018

    • Author(s)
      Takahashi T, Nagatoishi S, Kuroda D, Tsumoto K.
    • Journal Title

      PLoS One

      Volume: 13(10) Issue: 10 Pages: e0204856-e0204856

    • DOI

      10.1371/journal.pone.0204856

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
  • [Journal Article] Characterization of glycoengineered anti-HER2 monoclonal antibodies produced by using a silkworm?baculovirus expression system2018

    • Author(s)
      Egashira Y, Nagatoishi S, Kiyoshi M, Ishii-Watabe A, Tsumoto K.
    • Journal Title

      The Journal of Biochemistry

      Volume: 163 Issue: 6 Pages: 481-488

    • DOI

      10.1093/jb/mvy021

    • NAID

      40021579952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
  • [Journal Article] Discovery and Optimization of Inhibitors of the Parkinson’s Disease Associated Protein DJ-12018

    • Author(s)
      Tashiro Shinya、Caaveiro Jose M. M.、Nakakido Makoto、Tanabe Aki、Nagatoishi Satoru、Tamura Yasushi、Matsuda Noriyuki、Liu Dali、Hoang Quyen Q.、Tsumoto Kouhei
    • Journal Title

      ACS Chemical Biology

      Volume: 13 Issue: 9 Pages: 2783-2793

    • DOI

      10.1021/acschembio.8b00701

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H02443, KAKENHI-PROJECT-17J07322, KAKENHI-PROJECT-17K19338, KAKENHI-PROJECT-15H05705, KAKENHI-PROJECT-16H04710
  • [Journal Article] Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin2018

    • Author(s)
      Takumi Tashima , Satoru Nagatoishi, Jose M.M. Caaveiro, Makoto Nakakido, Hiroshi Sagara, Osamu Kusano-Arai, Hiroko Iwanari, Hitomi Mimuro, Takao Hamakubo, Shin-ichi Ohnuma and Kouhei Tsumoto
    • Journal Title

      Communications Biology

      Volume: 1:33 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s42003-018-0038-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17J10207, KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K19551, KAKENHI-PLANNED-18H05425
  • [Journal Article] Use of SpyTag/SpyCatcher to construct bispecific antibodies that target two epitopes of a single antigen.2017

    • Author(s)
      Yumura K, Akiba H, Nagatoishi S, Kusano-Arai O, Iwanari H, Hamakubo T, Tsumoto K.
    • Journal Title

      J. Biochem.

      Volume: 162 Issue: 3 Pages: 203-210

    • DOI

      10.1093/jb/mvx023

    • NAID

      40021326109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-25000006
  • [Journal Article] Biophysical characterization of the interaction between heme and proteins responsible for heme transfer in Streptococcus pyogenes.2017

    • Author(s)
      Hoshino M, Nakakido M, Nagatoishi S, Aikawa C, Nakagawa I, Tsumoto K.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 493 Issue: 2 Pages: 1109-1114

    • DOI

      10.1016/j.bbrc.2017.09.055

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08775, KAKENHI-PROJECT-17K19552, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H05188, KAKENHI-PROJECT-16H06693
  • [Journal Article] Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin2017

    • Author(s)
      S. Kudo, J. M. M. Caaveiro, S. Nagatoishi, T. Miyafusa, T. Matsuura, Y. Sudou, and K. Tsumoto
    • Journal Title

      Sci. Rep.

      Volume: 7 Issue: 1 Pages: 39518-39518

    • DOI

      10.1038/srep39518

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011
  • [Journal Article] Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers2017

    • Author(s)
      A. Pica, I. R. Krauss, V. Parente, H. Tateishi-Karimata, S. Nagatoishi, K. Tsumoto, N. Sugimoto, and F. Sica
    • Journal Title

      Nucleic Acids Res., 45, 461-469 (2017)

      Volume: 45 Issue: 1 Pages: 461-469

    • DOI

      10.1093/nar/gkw1113

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02283, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-26810094, KAKENHI-PROJECT-16H02420
  • [Journal Article] Structural basis for binding and transfer of heme in bacterial heme-acquisition systems2017

    • Author(s)
      Naoe Youichi、Nakamura Nozomi、Rahman Md. Mahfuzur、Tosha Takehiko、Nagatoishi Satoru、Tsumoto Kouhei、Shiro Yoshitsugu、Sugimoto Hiroshi
    • Journal Title

      Proteins: Structure, Function, and Bioinformatics

      Volume: 85 Issue: 12 Pages: 2217-2230

    • DOI

      10.1002/prot.25386

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05896, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-17H03092
  • [Journal Article] Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity.2017

    • Author(s)
      Lee Y, Nishizawa T, Takemoto M, Kumazaki K, Yamashita K, Hirata K, Minoda A, Nagatoishi S, Tsumoto K, Ishitani R and Nureki O.
    • Journal Title

      Nature Plants.

      Volume: 3 Issue: 10 Pages: 825-832

    • DOI

      10.1038/s41477-017-0022-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-16J07405, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000
  • [Journal Article] Thermodynamic analyses of amino acid residues at the interface of an antibody B2212A and its antigen roundabout homolog 1.2017

    • Author(s)
      Yui A, Akiba H, Kudo S, Nakakido M, Nagatoishi S and Tsumoto K
    • Journal Title

      J. Biochem.

      Volume: 162 Pages: 255-258

    • DOI

      10.1093/jb/mvx050

    • NAID

      40021380511

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H06693, KAKENHI-PROJECT-25000006
  • [Journal Article] The carboxyl-terminal region of Dok-7 plays a key, but not essential, role in activation of muscle-specific receptor kinase MuSK and neuromuscular synapse formation2017

    • Author(s)
      Ryo Ueta, Tohru Tezuka, Yosuke Izawa, Sadanori Miyoshi, Satoru Nagatoishi, Kouhei Tsumoto, Yuji Yamanashi
    • Journal Title

      The Journal of Biochemistry

      Volume: 161 Pages: 269-277

    • DOI

      10.1093/jb/mvw073

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14J08885, KAKENHI-PROJECT-16K14575, KAKENHI-PROJECT-15K18500
  • [Journal Article] Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage.2016

    • Author(s)
      Suzuki T, Nagatoishi S, Tsumoto K, Abe T. (全41人,5番目と25番目)
    • Journal Title

      J Am Soc Nephrol

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Journal Article] Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES.2016

    • Author(s)
      Kado Y1, Mizohata E2, Nagatoishi S3, Iijima M4, Shinoda K4, Miyafusa T3, Nakayama T2, Yoshizumi T2, Sugiyama A4, Kawamura T4, Lee YH4, Matsumura H2, Doi H4, Fujitani H4, Kodama T4, Shibasaki Y4, Tsumoto K5, Inoue T6.
    • Journal Title

      J Biol Chem.

      Volume: 291 Issue: 5 Pages: 2319-2330

    • DOI

      10.1074/jbc.m115.656009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670377, KAKENHI-PROJECT-15K17882, KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25440022, KAKENHI-PROJECT-25282230, KAKENHI-PUBLICLY-26102526
  • [Journal Article] Assessment of the Protein-Protein Interactions in a Highly Concentrated Antibody Solution by Using Raman Spectroscopy.2016

    • Author(s)
      Ota C, Noguchi S, Nagatoishi S, Tsumoto K
    • Journal Title

      Pharm. Res.

      Volume: 33(4) Issue: 4 Pages: 956-969

    • DOI

      10.1007/s11095-015-1842-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420
  • [Journal Article] Structural basis for amino-acid export by DMT superfamily transporter YddG2016

    • Author(s)
      H. Tsuchiya, S. Doki, M. Takemoto, T. Ikuta, T. Higuchi, K. Fukui, Y. Usuda, E. Tabuchi, S. Nagatoishi, K. Tsumoto, T. Nishizawa, K. Ito, N. Dohmae, R. Ishitani and O. Nureki
    • Journal Title

      Nature

      Volume: 534 Issue: 7607 Pages: 417-420

    • DOI

      10.1038/nature17991

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26410190, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-16H02420
  • [Journal Article] Differential binding of prohibitin-2 to estrogen receptor α and to drug-resistant ERα mutants.2015

    • Author(s)
      Chigira T, Nagatoishi S, Tsumoto K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 463 Issue: 4 Pages: 726-731

    • DOI

      10.1016/j.bbrc.2015.06.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011
  • [Journal Article] Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.2015

    • Author(s)
      Bai Y, Tashiro S, Nagatoishi S, Suzuki T, Yan D, Liu R, Tsumoto K, Bartlam M, Yamamoto T.
    • Journal Title

      Protein Cell.

      Volume: 6 Issue: 12 Pages: 924-928

    • DOI

      10.1007/s13238-015-0225-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J08172
  • [Journal Article] Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.2015

    • Author(s)
      Nakano K, Chigira T, Miyafusa T, Nagatoishi S, Caaveiro JM, Tsumoto K.
    • Journal Title

      Sci Rep.

      Volume: 5 Issue: 1 Pages: 15337-15337

    • DOI

      10.1038/srep15337

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115
  • [Journal Article] Osteomodulin regulates diameter and alters shape of collagen fibrils.2015

    • Author(s)
      Tashima T, Nagatoishi S, Sagara H, Ohnuma S, Tsumoto K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 463 Issue: 3 Pages: 292-296

    • DOI

      10.1016/j.bbrc.2015.05.053

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115
  • [Journal Article] Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses.2015

    • Author(s)
      Nakayama T, Mizohata E, Yamashita T, Nagatoishi S, Nakakido M, Iwanari H, Mochizuki Y, Kado Y, Yokota Y, Satoh R, Tsumoto K, Fujitani H, Kodama T, Hamakubo T, Inoue T.
    • Journal Title

      Protein Sci

      Volume: 24 Issue: 3 Pages: 328-340

    • DOI

      10.1002/pro.2619

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205
  • [Journal Article] Protein stabilization by an amphiphilic short monodisperse oligo(ethylene glycol)2015

    • Author(s)
      Nabanita Sadhukhan, Takahiro Muraoka, Mihoko Ui, Satoru Nagatoishi, Kouhei Tsumoto, Kazushi Kinbara
    • Journal Title

      Chemical Communications

      Volume: 51 Issue: 40 Pages: 8457-8460

    • DOI

      10.1039/c4cc10301g

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26410170, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25410166
  • [Journal Article] Thermodynamic characterization of the interaction between human Y-box binding protein YB-1 and nucleic acids2015

    • Author(s)
      Tanabe Y, Nagatoishi S, Tsumoto K.
    • Journal Title

      Mol. Biosyst.

      Volume: 11 Issue: 9 Pages: 2441-2448

    • DOI

      10.1039/c5mb00184f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011
  • [Journal Article] Reversible Ion Transportation Switch by a Ligand-Gated Synthetic Supramolecular Ion Channel2014

    • Author(s)
      Takahiro Muraoka, Takahiro Endo, Kazuhito V. Tabata, Hiroyuki Noji, Satoru Nagatoishi, Kouhei Tsumoto, Rui Li and Kazushi Kinbara
    • Journal Title

      Journal of the American Chemical Society

      Volume: 136 Issue: 44 Pages: 15584-15595

    • DOI

      10.1021/ja5070312

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23115003, KAKENHI-PROJECT-25249115
  • [Journal Article] Affinity Improvement of a Therapeutic Antibody by Structure-Based Computational Design : Generation of Electrostatic Interactions in the Transition State Stabilizes the Antibody-Antigen Complex2014

    • Author(s)
      Masato Kiyoshi, Jose M.M. Caaveiro, Eri Miura, Satoru Nagatoishi, Makoto Nakakido, Shinji Soga, Hiroki Shirai, Shigeki Kawabata, Kouhei Tsumoto
    • Journal Title

      Plos One

      Volume: 9 Issue: 1 Pages: e87099-e87099

    • DOI

      10.1371/journal.pone.0087099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25000006
  • [Journal Article] Identification and Characterization of the X-Dimer of Human P-Cadherin : Implications for Homophilic Cell Adhesion2014

    • Author(s)
      Shota Kudo, Jose M. M. Caaveiro, Shuichiro Goda, Satoru Nagatoishi, Keisuke Ishii, Tadashi Matsuura, Yukio Sudou, Tatsuhiko Kodama, Takao Hamakubo, and Kouhei Tsumoto
    • Journal Title

      Biochemistry

      Volume: 53(11) Issue: 11 Pages: 1742-1752

    • DOI

      10.1021/bi401341g

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J04678, KAKENHI-PROJECT-24000011, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25450133
  • [Journal Article] Hyperthin nanochains composed of self-polymerizing protein shackles2013

    • Author(s)
      Ryo Matsunaga, Saeko Yanaka, Satoru Nagatoishi, Kouhei Tsumoto
    • Journal Title

      Nature Communications

      Volume: 4 Issue: 1 Pages: 2211-2211

    • DOI

      10.1038/ncomms3211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J05539, KAKENHI-PROJECT-13J09564, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25249115
  • [Journal Article] Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer2013

    • Author(s)
      A. Pica, I. Russo Krauss, A. Merlino, S. Nagatoishi, N. Sugimoto, and F. Sica
    • Journal Title

      FEBS J.

      Volume: 280 Issue: 24 Pages: 6581-6588

    • DOI

      10.1111/febs.12561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24245033, KAKENHI-PROJECT-24750166
  • [Journal Article] DNA tetraplex structure formation from human telomeric repeat motif (TTAGGG) : (CCCTAA) in nanocavity water pools of reverse micelles2012

    • Author(s)
      S.Pramanik, S.Nagatoishi, N.Sugimoto
    • Journal Title

      Chem.Commun.

      Volume: 48 Issue: 40 Pages: 4815-4817

    • DOI

      10.1039/c2cc30622k

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22655057, KAKENHI-PROJECT-24245033, KAKENHI-PROJECT-24655161
  • [Journal Article] The yield of transcripts for RNA polymerase regulated by hairpin structures in nascent RNA2012

    • Author(s)
      S. Nagatoishi, R. Ono, and N. Sugimoto
    • Journal Title

      Chem. Commun.

      Volume: 48 Issue: 42 Pages: 5121-5123

    • DOI

      10.1039/c2cc31657a

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22655057, KAKENHI-PROJECT-24245033, KAKENHI-PROJECT-24655161
  • [Journal Article] Structural and Functional Characterization of RecG Helicase under Dilute and Molecular Crowding Conditions2012

    • Author(s)
      S. Saxena, S. Nagatoishi, D. Miyoshi and N. Sugimoto
    • Journal Title

      Journal of Nucleic Acids

      Volume: ID 392039 Pages: 392039-392039

    • DOI

      10.1155/2012/392039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24245033, KAKENHI-PROJECT-24350089, KAKENHI-PROJECT-24655161, KAKENHI-PROJECT-24750166, KAKENHI-PUBLICLY-24107525
  • [Journal Article] Interaction of water with the G-quadruplex loop contributes to the binding energy of G-quadruplex to protein2012

    • Author(s)
      S. Nagatoishi and N. Sugimoto
    • Journal Title

      Mol. Biosyst.

      Volume: 8 Issue: 10 Pages: 2766-2770

    • DOI

      10.1039/c2mb25234a

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24245033, KAKENHI-PROJECT-24655161, KAKENHI-PROJECT-24750166
  • [Journal Article] Hydration is Required in DNA G-Quadruplex-Protein Binding2011

    • Author(s)
      Nagatoishi S, Isono N, Tsumoto K, Sugimoto N
    • Journal Title

      Chembiochem.

      Volume: 12 Issue: 12 Pages: 1822-1826

    • DOI

      10.1002/cbic.201100264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-22655057
  • [Journal Article] Conformational flexibility influences degree of hydration of nucleic acid hybrids2011

    • Author(s)
      S.Pramanik, S.Nagatoishi, S.Saxena, J.Bhattacharyya, N.Sugimoto
    • Journal Title

      J.Phys.Chem.B

      Volume: 115 Issue: 47 Pages: 13862-13872

    • DOI

      10.1021/jp207856p

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Journal Article] Loop residues of thrombin-binding DNA aptamer impact G-quadruplex stability and thrombin binding2011

    • Author(s)
      S. Nagatoishi, N. Isono, K. Tsumoto, and N. Sugimoto
    • Journal Title

      Biochimie

      Volume: 93 Issue: 8 Pages: 1231-1238

    • DOI

      10.1016/j.biochi.2011.03.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Analytical Solutions for Research, Development & CMC of Novel Modalities of Drugs (I) ~Comprehensive Understanding of Molecular Structure, Dynamics and Function2023

    • Author(s)
      津本浩平,長門石曉
    • Organizer
      PITTCON 2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 物理化学解析を駆使した Protein-Protein Interaction阻害剤開発への挑戦2022

    • Author(s)
      長門石曉
    • Organizer
      創薬懇話会2022
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 様々なIgG型抗体に関するFcγRIIIaの物理化学的相互作用解析2022

    • Author(s)
      長門石曉, 小菅啓史, 木吉真人, 石井明子, 寺尾陽介, 井出輝彦, 津本浩平
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 表面電荷改変抗体のコロイド安定性・結合親和性とその溶媒依存性の解析2022

    • Author(s)
      笠原 慶亮、黒田 大祐、長門石 曉、津本 浩平
    • Organizer
      第60回 日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Monomer-Dimer Equilibrium of a Tumor Suppressor PRELP Driven by the Hydrophobic Interface Regulates the Multi-Specific Interactions2022

    • Author(s)
      Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
    • Organizer
      第22回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 計算科学により強化される 蛋白質のリガンド結合に関する物理化学解析2022

    • Author(s)
      長門石曉
    • Organizer
      第22回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 熱力学および速度論を基点とした蛋白質を制御する低分子リガンドの開発2022

    • Author(s)
      長門石曉
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Superchargingデザインは溶媒選択により抗体の物性を制御できる2022

    • Author(s)
      笠原 慶亮、黒田 大祐、河出 来時、田部 亜季、長門石 曉、津本 浩平
    • Organizer
      第22回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Rubredoxin A from M. tuberculosis2022

    • Author(s)
      Sushko T, J.M.M. Caaveiro, Nagatoishi S, Tsumoto K
    • Organizer
      10th Asian Biological Inorganic Chemistry (AsBIC10)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Capturing the Physical Properties of Highly-Concentrated Antibody Solutions from Raman Spectroscopic Analysis2022

    • Author(s)
      長門石曉
    • Organizer
      Pittcon 2022 Virtual Highlights JAIMA Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 抗体創薬のための物性解析:これまでとこれから2022

    • Author(s)
      長門石曉, 津本浩平
    • Organizer
      第1回日本抗体学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] FcγRIIIa受容体の固定化系と溶液系における抗体認識機構の解明2022

    • Author(s)
      長門石 曉、木下 清晶, 黒田 大祐, 小菅 啓史, 木吉 真人, 石井 明子, 寺尾 陽介, 井出 輝彦, 津本 浩平
    • Organizer
      第16回 バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 抗OX40アゴニスト小唄の相互作用に関する速度論的研究2022

    • Author(s)
      氏家 寛、田部 亜季,長門石 曉,津本 浩平
    • Organizer
      第16回 バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 生命分子に対する多元機能解明のための物理化学的相互作用解析2022

    • Author(s)
      長門石曉
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 新規抗体の機能解析に基づく抗CFH自己抗体によるaHUS発症機構モデルの提案2022

    • Author(s)
      横尾 尚典、田部 亜季、中木戸 誠、長門石 曉、カアベイロ ホセ、吉田 瑶子、池田 洋一郎、南学 正臣、津本 浩平
    • Organizer
      第22回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 生命分子に対する多元機能解明のための物理化学的相互作用解析2022

    • Author(s)
      長門石曉
    • Organizer
      第95回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Characterization of the regulatory system of multi-specific interactions of a novel tumor suppressor PRELP through the hydrophobicity-driven dimerization2022

    • Author(s)
      Kosuge H, Nakakido M, Nagatoishi S,Fukuda T, Bando Y, Ohnuma S, Tsumoto K
    • Organizer
      第21回 東京大学生命科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Search for Small Molecule Ligands That Functionally Regulate Proteins Based on Calorimetric Analysis2022

    • Author(s)
      Satoru Nagatoishi
    • Organizer
      11th Japan-China Joint Symposium on Calorimetry and Thermal Analysis (CATS-2022)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 様々なIgG型抗体に関するFcγRIIIaの物理化学的相互作用解析2022

    • Author(s)
      長門石曉, 小菅啓史, 木吉真人, 石井明子, 寺尾陽介, 井出輝彦, 津本浩平
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Search for Small Molecule Ligands That Functionally Regulate Proteins Based on Calorimetric Analysis2022

    • Author(s)
      長門石曉
    • Organizer
      11th Japan-China Joint Symposium on Calorimetry and Thermal Analysis (CATS-2022)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 抗体創薬のための物性解析:これまでとこれから2022

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第1回 日本抗体学会設立記念学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Physicochemical analysis of receptor recognition mechanism of anti-OX40 agonist antibodies2022

    • Author(s)
      氏家 寛、田部 亜季,長門石 曉,津本 浩平
    • Organizer
      第22回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 計算科学により強化される 蛋白質のリガンド結合に関する物理化学解析2022

    • Author(s)
      長門石曉
    • Organizer
      第22回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] FcγRIIIa受容体の固定化系と溶液系における抗体認識機構の解明2022

    • Author(s)
      長門石曉, 木下清晶, 黒田大祐, 小菅啓史, 木吉真人, 石井明子, 寺尾陽介, 井出輝彦, 津本浩平
    • Organizer
      第16回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Identification and validation of multi-specific interactions of a tumor suppressor protein PRELP2022

    • Author(s)
      Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
    • Organizer
      The 17th International Symposium of the Institute Network for Biomedical Sciences & International Symposium on Tumor Biology in Kanazawa 2022 (Hybrid Conference)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 物理化学解析を駆使した Protein-Protein Interaction阻害剤開発への挑戦2022

    • Author(s)
      長門石曉
    • Organizer
      創薬懇話会2022
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Interaction analysis between small-molecules and proteins using HDX-MS in physicochemical screening2021

    • Author(s)
      Satoru NAGATOISHI, Kouhei TSUMOTO
    • Organizer
      第69回質量分析総合討論会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 熱力学および速度論を基点とした蛋白質を制御する低分子リガンドの開発2021

    • Author(s)
      長門石曉
    • Organizer
      日本化学会 第102春季年会(若い世代の特別講演)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] M.R.S.A: fighting with antibodies2021

    • Author(s)
      Valenciano Bellido S, Caaveiro J.M.M, Nakakido M, Nagatoishi S, Tsumoto K.
    • Organizer
      2021年度医科研発表会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 化膿連鎖球菌由来金属獲得蛋白質MtsAに対する機能阻害剤の探索2021

    • Author(s)
      中木戸 誠、竹内 美結、長門石 曉、相川 知宏、中川 一路、津本 浩平
    • Organizer
      第94回 日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Interaction analysis between small-molecules and proteins using HDX-MS in physicochemical screening2021

    • Author(s)
      長門石曉, 津本浩平
    • Organizer
      第69回質量分析総合討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Design schemes for peptides imitating β-hairpin conformation of VHH CDR32021

    • Author(s)
      山本 晃一、中木戸 誠、黒田 大祐、長門石 曉、森本 淳平、山東 信介、津本 浩平
    • Organizer
      2021年度医科研発表会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 抗OX40抗体の受容体機能制御に関わる分子メカニズム解明2021

    • Author(s)
      氏家 寛、田部 亜季、長門石 曉、津本 浩平
    • Organizer
      第21回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Analysis of the molecular mechanisms involved in the recognition of antigen and the regulation of function by antibodies2021

    • Author(s)
      氏家 寛、田部 亜季、長門石 曉、津本 浩平
    • Organizer
      第44回 日本分子生物学会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] aHUSに関連する補体抑制因子CFHと診断薬取得に向けた特異的抗体の機能解析2021

    • Author(s)
      横尾 尚典、田部 亜季、中木戸 誠、長門石 曉、カアベイロ ホセ、吉田 瑶子、池田 洋一郎、南学 正臣、津本 浩平
    • Organizer
      第21回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Proteomic Identification and Validation of Novel Interactions of a Tumor Suppressor PRELP with the Growth Factor Receptors IGFI-R and p75NTR2021

    • Author(s)
      Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
    • Organizer
      第21回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 抗体表面への正荷電残基変異導入による抗体のpH非依存的な熱安定性獲得機構2021

    • Author(s)
      笠原 慶亮、黒田 大祐、河出 来時、田部 亜季、長門石 曉、津本 浩平
    • Organizer
      第59回 日本生物物理学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] A novel homodimerization mechanism of LI-cadherin2021

    • Author(s)
      Yui A, Caaveiro J.M.M, Kuroda D, Nakakido M, Nagatoishi S, Maruno T, Uchiyama S, Tsumoto K
    • Organizer
      The Protein Society 35th Annual Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Fragment-based screening and hit validation targeting enzymes and protein-protein interactions by SPR and ITC2021

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      PACIFICHEM 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 化膿連鎖球菌由来金属獲得蛋白質MtsAに対する機能阻害剤の探索2021

    • Author(s)
      中木戸 誠、竹内 美結、長門石 曉、相川 知宏、中川 一路、津本 浩平
    • Organizer
      第94回 日本細菌学会総会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] How SNPs in LI-cadherin gene increases the risk of cancer metastasis2021

    • Author(s)
      Yui A, Kikuchi C, Goda S, Kudo S, Akiba H, Nakakido M, Kuroda D, Nagatoishi S, Arai O, Iwanari H, Hamakubo T, Tsumoto K
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 滴定型熱量測定2021

    • Author(s)
      長門石 曉
    • Organizer
      第7回蛋白質工学研究会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Bioengineering of antibodies: the double antibody2021

    • Author(s)
      Valenciano S, Caaveiro J.M.M, Nakagawa I, Nakakido M, Nagatoishi S,Tsumoto K
    • Organizer
      UoT-MaC-UT workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] A novel homodimerization mechanism of LI-cadherin2021

    • Author(s)
      nna YuiJose M. M. Caaveiro, Daisuke Kuroda, Makoto Nakakido, Satoru Nagatoishi, Takahiro Maruno, Susumu Uchiyama, and Kouhei Tsumoto
    • Organizer
      The Protein Society 35th Annual Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] プロテオーム解析に基づく腫瘍抑制蛋白質PRELPと膜蛋白質の新規相互作用探索と機能解析2021

    • Author(s)
      小菅 啓史、中木戸 誠、長門石 曉、福田 哲也、板東 泰彦、大沼 信一、津本 浩平
    • Organizer
      第94回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 化膿連鎖球菌由来金属トランスポーターに対する機能阻害剤探索2021

    • Author(s)
      中木戸 誠、竹内 美結、伊藤 翔、相川 知宏、長門石 曉、中川 一路、津本 浩平
    • Organizer
      第21回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] aHUSに関連する補体抑制因子CFHと診断薬取得に向けた特異的抗体の機能解析2021

    • Author(s)
      発表者名: 横尾 尚典、田部 亜季、中木戸 誠、長門石 曉、カアベイロ ホセ、吉田 瑶子、池田 洋一郎、南学 正臣、津本 浩平
    • Organizer
      第21回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Analysis of the molecular mechanisms involved in the recognition of antigen and the regulation of function by antibodies2021

    • Author(s)
      氏家 寛、田部 亜季、長門石 曉、津本 浩平
    • Organizer
      第44回 日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 抗体表面への正荷電残基変異導入による抗体のpH非依存的な熱安定性獲得機構2021

    • Author(s)
      笠原 慶亮、黒田 大祐、河出 来時、田部 亜季、長門石 曉、津本 浩平
    • Organizer
      第59回 日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] プロテオーム解析に基づく腫瘍抑制蛋白質PRELPと膜蛋白質の新規相互作用探索と機能解析2021

    • Author(s)
      小菅 啓史、中木戸 誠、長門石 曉、福田 哲也、板東 泰彦、大沼 信一、津本 浩平
    • Organizer
      第94回 日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] VHH抗体の構造特徴を利用したβ-hairpin型ペプチド設計手法の探索2021

    • Author(s)
      山本 晃一、中木戸 誠、黒田 大祐、長門石 曉、森本 淳平、山東 信介、津本 浩平
    • Organizer
      第21回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 滴定型熱量測定2021

    • Author(s)
      長門石曉
    • Organizer
      第7回蛋白質工学研究会(日本蛋白質科学会創立20周年記念シンポジウム)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Proteomic Identification And Validation Of New Interactions Of Novel Tumor Suppressor PRELP With Membrane Proteins2020

    • Author(s)
      Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
    • Organizer
      第20回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 物理化学的スクリーニングにおけるHDX-MSを用いた低分子-タンパク質間相互作用解析2020

    • Author(s)
      長門石曉
    • Organizer
      第69回質量分析総合討論会2020
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Thermodynamic selection of ligands to inhibit the protein functions in cell and in vivo2020

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      The 7th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS 2020)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Obtaining antibodies against Staphyloccus aureus2020

    • Author(s)
      Valenciano S, Sandra Bellido, Jose M.M. Caaveiro, Nakakido M, Nagatoishi S, Tsumoto K
    • Organizer
      2020年度 医科学研究所G2発表会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 計算デザイン Supercharging 抗体の物性機能解析2020

    • Author(s)
      笠原 慶亮、黒田 大祐 、河出 来時 、田部 亜季 、長門石 曉 、津本 浩平
    • Organizer
      第48回 構造活性相関シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Inhibition of P-cadherin-mediated cell contact formation through the kinetic effect of chemical fragment2020

    • Author(s)
      妹尾 暁暢、齋藤 雄太朗、伊藤 翔、長門石 曉、上野 剛、吉田 浩平、田島 卓実、工藤 翔太、山東 信介、津本 浩平
    • Organizer
      第20回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 熱力学および速度論を活用した低分子薬剤スクリーニング技術開発2020

    • Author(s)
      長門石曉
    • Organizer
      甲南大学先端生命工学研究所 FIBER FUTURE COLLEGE 69
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 蛋白質-蛋白質間相互作用の速度論的制御に基づくP-カドヘリンの細胞接着形成阻害2020

    • Author(s)
      妹尾 暁暢、長門石 曉、黒田 大祐、伊藤 翔、上野 剛、齋藤 雄太朗、吉田 浩平、田島 卓実、工藤 翔太、山東 信介、津本 浩平
    • Organizer
      第14回 バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] 計算デザイン Supercharging 抗体の物性機能解析2020

    • Author(s)
      笠原 慶亮、黒田 大祐 、河出 来時 、田部 亜季 、長門石 曉 、津本 浩平
    • Organizer
      第48回 構造活性相関シンポジウム
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 化膿連鎖球菌の金属獲得蛋白質MtsAに対する機能阻害剤の探索2020

    • Author(s)
      竹内 美結、中木戸 誠、長門石 曉、河出 来時、相川 知宏、中川 一路、津本 浩平
    • Organizer
      第93回 日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Molecular basis of increased risk of colorectal cancer metastasis caused by SNPs in LI-cadherin2020

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、丸野 孝浩、内山 進、中木戸 誠、黒田大祐、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第58回 日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] VHH抗体β-hairpin型CDR3を利用したペプチド設計手法の探索2020

    • Author(s)
      山本晃一、中木戸 誠、黒田 大祐、長門石 曉、森本 淳平、山東 信介、津本 浩平
    • Organizer
      第43回 日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Application of β-hairpin structure of VHH CDR3 for peptide designs2020

    • Author(s)
      山本 晃一、中木戸 誠、黒田 大祐、長門石 曉、森本 淳平、山東 信介、津本 浩平
    • Organizer
      2020年度 医科学研究所G2発表会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] aHUSに関連する補体抑制因子CFHと特異的抗体の機能解析2020

    • Author(s)
      横尾 尚典、田部 亜季、中木戸 誠、長門石 曉、吉田 瑶子、池田 洋一郎、南学 正臣、津本 浩平
    • Organizer
      第93回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Proteomic Identification And Validation Of New Interactions Of Novel Tumor Suppressor PRELP With Membrane Proteins2020

    • Author(s)
      Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
    • Organizer
      第20回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] VHH抗体β-hairpin型CDR3を利用したペプチド設計手法の探索2020

    • Author(s)
      山本晃一、中木戸 誠、黒田 大祐、長門石 曉、森本 淳平、山東 信介、津本 浩平
    • Organizer
      第43回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] HDX-MSを活用したP-カドヘリンのホモ複合体に対する低分子阻害剤開発2020

    • Author(s)
      妹尾 暁暢、長門石 曉、伊藤 翔、上野 剛、津本 浩平
    • Organizer
      第16回 日本臨床プロテオゲノミクス研究会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] My research in Tokyo2020

    • Author(s)
      Valenciano-Bellido Sandra, Caaveiro Jose M.M, Nakakido M, Nagatoishi S and Tsumoto K
    • Organizer
      I Iberoamerican research encounter in Japan (organized by ACE Japón, Spanish Embassy and Instituto Cervantes)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 蛋白質-蛋白質間相互作用の速度論的制御に基づくP-カドヘリンの細胞接着形成阻害2020

    • Author(s)
      妹尾 暁暢、長門石 曉、黒田 大祐、伊藤 翔、上野 剛、齋藤 雄太朗、吉田 浩平、田島 卓実、工藤 翔太、山東 信介、津本 浩平
    • Organizer
      第14回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 物理化学から低分子リガンドを探索・創出する2020

    • Author(s)
      長門石曉
    • Organizer
      第1回「生体適合化学の進歩」インタラクティブフォーラム(ABC-InFO)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] aHUSに関連する補体抑制因子CFHと特異的抗体の機能解析2020

    • Author(s)
      横尾 尚典、田部 亜季、中木戸 誠、長門石 曉、吉田 瑶子、池田 洋一郎、南学 正臣、津本 浩平
    • Organizer
      第93回 日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 化膿連鎖球菌の金属獲得蛋白質MtsAに対する機能阻害剤の探索2020

    • Author(s)
      竹内 美結、中木戸 誠、長門石 曉、河出 来時、相川 知宏、中川 一路、津本 浩平
    • Organizer
      第93回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] The Molecular Basis of How SNP in LI-cadherin Affected Cancer Metastasis2020

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、黒田大祐、長門石 曉
    • Organizer
      第20回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] The Molecular Basis of How SNP in LI-cadherin Affected Cancer Metastasis2020

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、黒田大祐、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第20回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Inhibition of P-cadherin-mediated cell contact formation through the kinetic effect of chemical fragment2020

    • Author(s)
      妹尾 暁暢、齋藤 雄太朗、伊藤 翔、長門石 曉、上野 剛、吉田 浩平、田島 卓実、工藤 翔太、山東 信介、津本 浩平
    • Organizer
      第20回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] HDX-MSを活用したP-カドヘリンのホモ複合体に対する低分子阻害剤開発2020

    • Author(s)
      妹尾 暁暢、長門石 曉、伊藤 翔、上野 剛、津本 浩平
    • Organizer
      第16回 日本臨床プロテオゲノミクス研究会
    • Data Source
      KAKENHI-PROJECT-20H02531
  • [Presentation] Molecular basis of increased risk of colorectal cancer metastasis caused by SNPs in LI-cadherin2020

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、丸野 孝浩、内山 進、中木戸 誠、黒田大祐、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第58回 日本生物物理学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Calorimetric Selection of Ligands to Inhibit the Protein Functions in Cell and in Vivo2019

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      The Seventh International Symposium on the New Frontiers of Thermal Studies of Materials
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Disruption of Homophilic Protein-protein Interaction of P-cadherin by A Fragment Compound as A Trigger To Inhibit Cell Adhesion2019

    • Author(s)
      妹尾 暁暢、長門石 曉、吉田 浩平、伊藤 翔、上野 剛、田島 卓実、工藤 翔太、津本 浩平
    • Organizer
      33rd The Protein Society Annual Symposium
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Biophysics of the Protein-ligand Interactions to Regulate the Protein Function2019

    • Author(s)
      S Nagatoishi、K Tsumoto
    • Organizer
      10th RSC-CSJ Joint Symposium
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Thermodynamic selection of ligands to inhibit the protein functions in cell and in vivo2019

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      The 7th International Postgraduate Conference on Pharmaceutical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] ホモ二量体形成蛋白質P-カドヘリンによる細胞接着阻害を可能にする新規低分子リガンド結合部位の同定2019

    • Author(s)
      妹尾暁暢、長門石曉、吉田浩平、伊藤翔、上野剛、田島卓実、工藤翔太、津本浩平
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Elucidation of the interactions for natural flexible and unstable proteins using HDX-MS2019

    • Author(s)
      長門石 曉、津本 浩平
    • Organizer
      第65回質量分析総合討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] S100A4-MetAP2間相互作用に対するHelix-turn-helix構造を形成するペプチド 阻害剤の解析2019

    • Author(s)
      片桐直宏、長門石曉、遠藤英也、津本浩平
    • Organizer
      第37回 メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Structural insight into inhibition of homophilic dimerization mediated by cell adhesion protein P-cadherin utilizing a small molecule ligand2019

    • Author(s)
      妹尾 暁暢、長門石 曉、吉田 浩平、伊藤 翔、上野 剛、田島 卓実、工藤 翔太、津本 浩平
    • Organizer
      第19回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Mechanism of action of IsdH from Staphylococcus aureus2019

    • Author(s)
      Valenciano-Bellido Sandra, Caaveiro Jose M.M, Nakakido M, Nagatoishi S and Tsumoto K
    • Organizer
      II Annual Meeting of the Spanish asociation of researchers in Japan (ACE Japón)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 低分子リガンドによる細胞接着蛋白質P-カドヘリンの同種親和的二量体化阻害に対する分子機構解明2019

    • Author(s)
      妹尾暁暢、長門石曉、吉田浩平、伊藤翔、上野剛、田島卓実、工藤翔太、津本浩平
    • Organizer
      第19回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Calorimetric Selection of Ligands to Inhibit the Protein Functions in Cell and in Vivo2019

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      The Seventh International Symposium on the New Frontiers of Thermal Studies of Materials
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 生体分子を制御する特異的リガンドの物理化学的探索と解析2019

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      生有研シンポジウム 2019
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] がん関連蛋白質を阻害する特異的リガンドの物理化学的探索2019

    • Author(s)
      長門石 曉、津本 浩平
    • Organizer
      第三回 徳島大学統合的がん創薬研究クラスター 合同ミーティング
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] がん転移に関するLI-cadherin一塩基多型の分子メカニズム2019

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、黒田 大祐、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第92回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 生体内の標的蛋白質を制御するための熱的アプローチによるリガンド選抜2019

    • Author(s)
      長門石 曉、津本 浩平
    • Organizer
      Chemistry for Neuroscience 2019
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 蛋白質-リガンド, 抗原-抗体相互作用解析における熱分析の活用2019

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      熱測定スプリングスクール2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Development and analysis of bispecific antibody for hROBO12019

    • Author(s)
      Yuji Watanabe, Makoto Nakakido, Satoru Nagatoishi, Takao Hamakubo, Kouhei Tsumoto
    • Organizer
      Antibody Engineering & Therapeutics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 医薬品設計の提案を指向したHDX-MSによる蛋白質間相互作用解析2019

    • Author(s)
      長門石曉、 展天承、 森千夏、 中木戸誠、 津本浩平
    • Organizer
      第15回日本臨床プロテオゲノミクス研究会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] S100A4-MetAP2蛋白質間相互作用に対するペプチド阻害剤の相互作用解析2019

    • Author(s)
      片桐直宏、長門石曉、遠藤英也、津本浩平
    • Organizer
      第19回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 熱測定によるリガンドの阻害活性や結合様式の同定2019

    • Author(s)
      長門石 曉、津本 浩平
    • Organizer
      第55回熱測定討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 小分子リガンドによる細胞接着蛋白質P-カドヘリンの分子間相互作用制御と構造情報に基づくリガンド設計2019

    • Author(s)
      妹尾暁暢、齋藤雄太朗、伊藤翔、長門石曉、上野剛、吉田浩平、田島卓実、工藤翔太、山東信介、津本浩平
    • Organizer
      第13回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Molecular mechanism of how SNP in LI-cadherin affected cancer metastasis2019

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、黒田 大祐、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      G2 Plus Retreat
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 蛋白質相互作用の熱測定と創薬2019

    • Author(s)
      長門石 曉、津本 浩平
    • Organizer
      第57回 日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Development and analysis of bispecific antibody for hROBO1.2019

    • Author(s)
      Yuji Watanabe, Makoto Nakakido, Satoru Nagatoishi, Takao Hamakubo, Kouhei Tsumoto
    • Organizer
      Antibody Engineering & Therapeutics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] ホモ二量体形成蛋白質P-カドヘリンによる細胞接着阻害を可能にする新規低分子リガンド結合部位の同定2019

    • Author(s)
      妹尾 暁暢、長門石 曉、吉田 浩平、伊藤 翔、上野 剛、田島 卓実、工藤 翔太、津本 浩平
    • Organizer
      第92回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain.2019

    • Author(s)
      Valenciano-Bellido Sandra, Caaveiro Jose M.M, Nakakido M, Nagatoishi S and Tsumoto K
    • Organizer
      Bioengineering seminar; The University of Tokyo
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Local hydrophobic exposure of proteins regulated by hydration changes and its adsorption on a COP plastic surface2019

    • Author(s)
      長門石 曉、津本 浩平
    • Organizer
      第19回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 生体分子を制御する特異的リガンドの物理化学的探索と解析2019

    • Author(s)
      長門石 曉、津本 浩平
    • Organizer
      生有研シンポジウム 2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 物理化学的手法を駆使した細胞接着蛋白質P-カドヘリンのホモ二量体化相互作用を阻害する低分子の同定とその阻害機構解明2019

    • Author(s)
      妹尾暁暢、齋藤雄太朗、伊藤翔、長門石曉、上野剛、吉田浩平、田島卓実、工藤翔太、山東信介、津本浩平
    • Organizer
      第37回 メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Calorimetric ligand selection to regulate the target protein-protein interactions2019

    • Author(s)
      長門石 曉、津本 浩平
    • Organizer
      第37回 メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] hermodynamic, kinetic and computational analyses of the recognition mechanism of an antibody to a flexible protein antigen2019

    • Author(s)
      金田 生穂、長門石 曉、黒田 大祐、中木戸 誠、カアベイロ ホセ、津本 浩平
    • Organizer
      CBI学会2019年大会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Elucidation of the interactions for natural flexible and unstable proteins using HDX-MS2019

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第65回質量分析総合討論会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 蛋白質-リガンド, 抗原-抗体相互作用解析における熱分析の活用2019

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      熱測定スプリングスクール2019
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] SPRを用いた化膿連鎖球菌の宿主感染関連PPIを阻害する天然物化合物の探索2018

    • Author(s)
      妹尾 暁暢、長門石 曉、中木戸 誠、星野 将人、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] A群レンサ球菌の増殖を抑制する新規薬剤の探索と評価2018

    • Author(s)
      相川知宏、星野将人、中木戸誠、長門石暁、津本浩平、中川一路
    • Organizer
      第71回日本細菌学会関西支部総会
    • Data Source
      KAKENHI-PROJECT-17K19552
  • [Presentation] 合理的な抗体設計を目指した蛋白質相互作用に関する物理化学解析2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      バイオ医薬品セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Nanodisc を用いたリン脂質二重膜環境中におけるヒトセロトニン受容体の機能解析2018

    • Author(s)
      吉田 浩平、黒田 大祐、長門石 曉、津本 浩平
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] ドラッグデリバリーの標的特異性創出を目的と した部位特異的化学修飾可能な抗 OX40単鎖 抗体の取得と機能解析2018

    • Author(s)
      田部 亜季、中野 和民、中木戸 誠、長門石 曉、田中 勇悦、津本 浩平、内丸 薫、渡邉 俊樹
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 蛋白質相互作用の物理化学的解析と次世代創薬2018

    • Author(s)
      津本浩平、長門石曉
    • Organizer
      第56回生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] SPRを用いた化膿連鎖球菌の宿主感染関連PPIを阻害する天然物化合物の探索2018

    • Author(s)
      妹尾 暁暢、長門石 曉、中木戸 誠、星野 将人、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 化膿連鎖球菌の鉄獲得機構を阻害する新規低分子・抗体の取得2018

    • Author(s)
      妹尾 暁暢、星野 将人、中木戸 誠、長門石 曉、相川 知宏、中川 一路、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 細胞内の蛋白質間相互作用を制御する物理化学的リガンド探索2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] Nanodisc-GPCRを用いた物理化学的アプローチによる低分子薬剤探索2018

    • Author(s)
      吉田 浩平、長門石 曉、黒田 大祐、津本 浩平
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 病原性微生物における鉄獲得関連蛋白質の物理化学解析と新規抗菌剤の探索2018

    • Author(s)
      中木戸 誠、妹尾 暁暢、サンドラ バレンシアノ、星野 将人、相川 知宏、長門石 曉、ホセ カアベイロ、中川 一路、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] SAXS及びITCによるホモ二量体形成蛋白質LI-cadherinの物性解析2018

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 化膿連鎖球菌の鉄獲得機構を阻害する新規低分子・抗体の取得2018

    • Author(s)
      妹尾 暁暢、星野 将人、中木戸 誠、長門石 曉、相川 知宏、中川 一路、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] SPRを用いた化膿連鎖球菌の宿主感染関連PPIを阻害する天然物化合物の探索2018

    • Author(s)
      妹尾 暁暢、長門石 曉、中木戸 誠、星野 将人、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Raman Spectroscopy for Biopharmaceutics: Evaluation of Conformational Stability2018

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      RamanFest 2018 (6th International Conference on Advanced Applied Raman Spectroscopy)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Physicochemical and Computational Analysis for S100A4-MetAP2 peptide Interaction2018

    • Author(s)
      Naohiro Katagiri, Satoru Nagatoishi, Hideya Endo, Kouhei Tsumoto
    • Organizer
      sian Biophysics Association Symposium in conjunction with the Australian Society for Biophysics Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 蛋白質相互作用の物理化学的解析と次世代創薬2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第56回生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] リステリア菌感染におけるE-cadherin-InlA間相互作用を阻害する低分子及びVHHの探索2018

    • Author(s)
      山﨑 太一、長門石 曉、中木戸 誠、ホセ カアベイロ、三室 仁美、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 天然変性タンパク質のフラグメント化によるタンパク質間相互作用阻害リガンド探索2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] Physicochemical and Computational Analysis for S100A4-MetAP2 peptide Interaction2018

    • Author(s)
      Naohiro Katagiri, Satoru Nagatoishi, Hideya Endo, Kouhei Tsumoto
    • Organizer
      Asian Biophysics Association Symposium in conjunction with the Australian Society for Biophysics Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 細胞内の蛋白質間相互作用を制御する物理化学的リガンド探索2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 病原性微生物における鉄獲得関連蛋白質の物理化学解析と新規抗菌剤の探索2018

    • Author(s)
      中木戸 誠、妹尾 暁暢、サンドラ バレンシアノ、星野 将人、相川 知宏、長門石 曉、ホセ カアベイロ、中川 一路、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] FcRカラムを用いた異なる細胞種由来IgGの糖鎖解析2018

    • Author(s)
      小菅 啓史、長門石 曉, 中木戸 誠, 黒田 大祐, 木吉 真人, 石井 明子, 寺尾 陽介, 朝岡 義晴, 大江 正剛, 井出 輝彦, 津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 物理化学測定を用いた異なる脂質環境におけるセロトニン受容体の機能評価2018

    • Author(s)
      吉田 浩平、長門石 曉、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] LI-cadherinのTrp残基への変異導入がホモ二量体形成に与える影響2018

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 化膿連鎖球菌に対する抗菌剤開発を指向したヘム受容体-Hemoglobin間相互作用制御剤の探索2018

    • Author(s)
      妹尾 暁暢、長門石 曉、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 蛋白質相互作用の物理化学的解析と次世代創薬2018

    • Author(s)
      津本浩平、長門石曉
    • Organizer
      第56回生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 天然変性タンパク質のフラグメント化によるタンパク質間相互作用阻害リガンド探索2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 細胞内の蛋白質間相互作用を制御する物理化学的リガンド探索2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] SPRを活用した鉄獲得機構を標的とした化膿連鎖球菌に対する新規抗菌剤の探索2018

    • Author(s)
      妹尾 暁暢、長門石 曉、福田 哲也、小尾 奈緒子、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 物理化学測定を用いた異なる脂質環境におけるセロトニン受容体の機能評価2018

    • Author(s)
      吉田 浩平、長門石 曉、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] LI-cadherinのTrp残基への変異導入がホモ二量体形成に与える影響2018

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] シングルドメイン抗体を用いたインターロイキンのシグナル制御2018

    • Author(s)
      森 千夏、中木戸 誠、長門石 曉、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 金属プロテアーゼShhに対する抗体5E1の熱力学・速度論解析2018

    • Author(s)
      金田 生穂、長門石 曉、中木戸 誠、津本 浩平
    • Organizer
      第46回 構造活性相関シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] SPRを活用した鉄獲得機構を標的とした化膿連鎖球菌に対する新規抗菌剤の探索2018

    • Author(s)
      妹尾 暁暢、長門石 曉、福田 哲也、小尾 奈緒子、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 天然変性タンパク質のフラグメント化によるタンパク質間相互作用阻害リガンド探索2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Nanodisc-GPCRを用いた物理化学的アプローチによる低分子薬剤探索2018

    • Author(s)
      吉田 浩平、長門石 曉、黒田 大祐、津本 浩平
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 転写調節因子PRDM14の天然変性領域とEED間における物理化学的相互作用解析2018

    • Author(s)
      大西 亮輔、長門石 曉、谷口 博昭、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] 化膿連鎖球菌に対する抗菌剤開発を指向したヘム受容体-Hemoglobin間相互作用制御剤の探索2018

    • Author(s)
      妹尾 暁暢、長門石 曉、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] FcRカラムを用いた異なる細胞種由来IgGの糖鎖解析2018

    • Author(s)
      小菅 啓史、長門石 曉, 中木戸 誠, 黒田 大祐, 木吉 真人, 石井 明子, 寺尾 陽介, 朝岡 義晴, 大江 正剛, 井出 輝彦, 津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Nanodisc-GPCRを用いた物理化学的アプローチによる低分子薬剤探索2018

    • Author(s)
      吉田 浩平、長門石 曉、黒田 大祐、津本 浩平
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 合理的な抗体設計を目指した蛋白質相互作用に関する物理化学解析2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      バイオ医薬品セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Nanodisc を用いたリン脂質二重膜環境中におけるヒトセロトニン受容体の機能解析2018

    • Author(s)
      吉田 浩平、黒田 大祐、長門石 曉、津本 浩平
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Regulation of collagen fibril formation and stabilization by leucine rich repeat protein, OMD2018

    • Author(s)
      中木戸 誠、田島卓実、長門石曉、大沼信一、津本浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] ドラッグデリバリーの標的特異性創出を目的とした部位特異的化学修飾可能な抗 OX40単鎖抗体の取得と機能解析2018

    • Author(s)
      田部 亜季、中野 和民、中木戸 誠、長門石 曉、田中 勇悦、津本 浩平、内丸 薫、渡邉 俊樹
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 細胞内の蛋白質間相互作用を制御する物理化学的リガンド探索2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] Physicochemical and Computational Analysis for S100A4-MetAP2 peptide Interaction2018

    • Author(s)
      Naohiro Katagiri, Satoru Nagatoishi, Hideya Endo, Kouhei Tsumoto
    • Organizer
      Asian Biophysics Association Symposium in conjunction with the Australian Society for Biophysics Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 肝がん細胞に発現するROBO1抗原に対する二重特異性抗体の開発2018

    • Author(s)
      渡邉 裕治、中木戸 誠、長門石 曉、浜窪 隆雄、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 肝がん細胞に発現するROBO1抗原に対する二重特異性抗体の開発2018

    • Author(s)
      渡邉 裕治、中木戸 誠、長門石 曉、浜窪 隆雄、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 抗体の阻害機構解明や親和性向上設計のための熱測定2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第18回日本蛋白質学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Nanodiscを用いたリン脂質二重膜環境中におけるヒトセロトニン受容体の機能解析2018

    • Author(s)
      吉田 浩平、黒田 大祐、長門石 曉、津本 浩平
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] LI-cadherinのTrp残基への変異導入がホモ二量体形成に与える影響2018

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 天然変性タンパク質のフラグメント化によるタンパク質間相互作用阻害リガンド探索2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] SPRを活用した鉄獲得機構を標的とした化膿連鎖球菌に対する新規抗菌剤の探索2018

    • Author(s)
      妹尾 暁暢、長門石 曉、福田 哲也、小尾 奈緒子、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-18H05425
  • [Presentation] 物理化学測定を用いた異なる脂質環境におけるセロトニン受容体の機能評価2018

    • Author(s)
      吉田 浩平、長門石 曉、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 蛋白質-リガンド, 抗原-抗体相互作用解析における熱分析の活用2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      熱測定スプリングスクール2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] リステリア菌感染におけるE-cadherin-InlA間相互作用を阻害する低分子及びVHHの探索2018

    • Author(s)
      山﨑 太一、長門石 曉、中木戸 誠、ホセ カアベイロ、三室 仁美、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] SAXS及びITCによるホモ二量体形成蛋白質LI-cadherinの物性解析2018

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] SAXS及びITCによるホモ二量体形成蛋白質LI-cadherinの物性解析2018

    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 転写調節因子PRDM14の天然変性領域とEED間における物理化学的相互作用解析2018

    • Author(s)
      大西 亮輔、長門石 曉、谷口 博昭、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] Regulation of collagen fibril formation and stabilization by leucine rich repeat protein, OMD2018

    • Author(s)
      中木戸 誠、田島卓実、長門石曉、大沼信一、津本浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Raman Spectroscopy for Biopharmaceutics: Evaluation of Conformational Stability2018

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      RamanFest 2018 (6th International Conference on Advanced Applied Raman Spectroscopy)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 転写調節因子PRDM14の天然変性領域とEED間における物理化学的相互作用解析2018

    • Author(s)
      大西 亮輔、長門石 曉、谷口 博昭、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] シングルドメイン抗体を用いたインターロイキンのシグナル制御2018

    • Author(s)
      森 千夏、中木戸 誠、長門石 曉、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 抗体の阻害機構解明や親和性向上設計のための熱測定2018

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第18回日本蛋白質学会年会
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 金属プロテアーゼShhに対する抗体5E1の熱力学・速度論解析2018

    • Author(s)
      金田 生穂、長門石 曉、中木戸 誠、津本 浩平
    • Organizer
      第46回構造活性相関シンポジウム
    • Data Source
      KAKENHI-PROJECT-18H02082
  • [Presentation] 熱分析から低分子薬剤の探索・設計に挑む2017

    • Author(s)
      長門石曉、津本浩平、Caaveiro Jose
    • Organizer
      第30回 九州分析化学若手の会 春の講演会
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] 創薬研究におけるITCとサーマルシフトの活用2017

    • Author(s)
      長門石 曉
    • Organizer
      :熱測定スプリングスクール2017(第78回熱測定講習会)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 低分子創薬の技術開発における物理化学バリデーション2017

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第30回 バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] 蛋白質相互作用の熱力学解析と創薬2017

    • Author(s)
      津本浩平, 長門石曉
    • Organizer
      日本ケミカルバイオロジー学会第12回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 蛋白質相互作用の物理化学解析に基づくリガンドスクリーニング2017

    • Author(s)
      津本浩平, 長門石曉
    • Organizer
      日本化学会第98春季年会2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] hermodynamic elucidation of binding process for protein-ligand interactions to propose a drug design2017

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] ホモ2量体形成蛋白質P-cadherinを標的とした蛋白質間相互作用阻害剤の探索2017

    • Author(s)
      妹尾暁暢、田島卓実、工藤翔太、長門石曉、津本浩平
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] LI-cadherinのホモダイマー形成の細胞アッセイ及び物理化学的手法による分析2017

    • Author(s)
      由井杏奈、菊池智佳、工藤翔太、秋葉宏樹、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
    • Organizer
      日本化学会第97春季年会(2017)
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 物理化学的アプローチによる蛋白質間相互作用阻害剤の探索2017

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第65回 質量分析総合討論会
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] 物理化学的アプローチによる蛋白質間相互作用阻害剤の探索2017

    • Author(s)
      長門石曉, 津本浩平
    • Organizer
      第65回質量分析総合討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] シクロオレフィンポリマーCOP表面に対するホフマイスター効果に依存したタンパク質吸着制御2017

    • Author(s)
      長門石曉、藤田梨紗子、足達慧、西岡寛哉、二宮英隆、彼谷高敏、高井まどか、津本浩平
    • Organizer
      第11回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 創薬研究における ITCとサーマルシフトの活用2017

    • Author(s)
      長門石 曉
    • Organizer
      熱測定スプリングスクール2017(第78回熱測定講習会)
    • Place of Presentation
      早稲田大学西早稲田キャンパス(新宿区
    • Year and Date
      2017-03-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] 低分子創薬の技術開発における物理化学バリデーション2017

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 天然変性蛋白質Mint3とFIH-1の相互作用解析におけるH/D交換質量分析法の適用2017

    • Author(s)
      展 天承、中山 佳昭、長門石 曉、坂本 毅治、清木 元治、津本 浩平
    • Organizer
      第65回質量分析総合討論会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 次世代の低分子創薬を拓く蛋白質-低分子間相互作用の物理化学的解析2017

    • Author(s)
      長門石曉, Caaveiro Jose, 津本浩平
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      東北大学川内キャンパス
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] 次世代の低分子創薬を拓く蛋白質-低分子間相互作用の物理化学的解析2017

    • Author(s)
      長門石 曉、カアベイロホセ、津本浩平
    • Organizer
      日本薬学会第137年会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 神経筋接合部の形成に必要な受容体型キナーゼMuSKのDok-7による活性化機構の解明2017

    • Author(s)
      植田亮、手塚徹、井澤洋介、三好貞徳、長門石暁、津本浩平、山梨裕司
    • Organizer
      日本筋学会第3回学術集会
    • Data Source
      KAKENHI-PROJECT-15K18500
  • [Presentation] Thermodynamic elucidation of binding process for protein-ligand interactions to propose a drug design2017

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第55回 日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] 熱分析から低分子薬剤の探索・設計に挑む2017

    • Author(s)
      長門石曉, Caaveiro Jose, 津本浩平
    • Organizer
      第30回九州分析化学若手の会 春の講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Thermodynamics of the interaction between proteins and small compounds in drug discovery2016

    • Author(s)
      長門石曉
    • Organizer
      分子研研究会
    • Place of Presentation
      岡崎コンファレンスセンター(愛知県岡崎市)
    • Year and Date
      2016-06-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] 熱力学的解析を基盤とした茶カテキン- 蛋白質間の分子認識2016

    • Author(s)
      高橋知也、長門石曉、津本浩平
    • Organizer
      第16回日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-06-07
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Thermodynamic analysis of molecular recognition between tea catechins and human serum albumin2016

    • Author(s)
      Tomoya Takahashi, Sartoru Nagatoishi, Daisuke Kuroda, Kouhei Tsumoto
    • Organizer
      CALCON2016
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Biophysical approach to find the inhibitors of CapF and ERK2 enzyme in FBDD2016

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      JCUP VII
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Calorimetric characterization of the interaction between an intrinsically disordered protein YB-1 and nucleic acids.2016

    • Author(s)
      Satoru Nagatoishi, Tsumoto Kouhei
    • Organizer
      CALCON 2016
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2016-08-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] コラーゲン線維形成プロセスを制御する蛋白質Osteomodulinの制御機構解析2016

    • Author(s)
      田島卓実、長門石暁、カアベイロホセ、中木戸誠、相良洋、大沼信一、津本浩平
    • Organizer
      第10回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 次世代抗体開発を指向したin silicoとin vitroをつなぐ熱力学解析2016

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      バイオプロセス講演会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] TRAF6-Ubc13蛋白質間相互作用の低分子阻害剤スクリーニングに向けた相互作用解析2016

    • Author(s)
      展天承・長門石曉・井上純一郎・津本浩平
    • Organizer
      第136年会 日本薬学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] プロセス熱力学に基づく蛋白質-低分子間相互作用の解析と薬剤設計の提案2016

    • Author(s)
      長門石曉、山口奏、津本浩平
    • Organizer
      第16回日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-06-07
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] 次世代薬剤設計を指向した蛋白質-低分子間相互作用のプロセス熱力学2016

    • Author(s)
      長門石曉、 山口奏、津本浩平
    • Organizer
      第10回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] SPR and ITC-based small-molecule screening to find inhibitors of protein-protein interactions.2016

    • Author(s)
      Satoru Nagatoishi, Tsumoto Kouhei
    • Organizer
      Developments in Protein Interaction Analysis, DiPIA2016
    • Place of Presentation
      Crowne Plaza Berlin City Center, Berlin, Germany
    • Year and Date
      2016-06-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Biophysical approach to find the inhibitors of CapF and ERK2 enzyme in FBDD.2016

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      JCUP VII
    • Place of Presentation
      大手町サンスカイルーム
    • Year and Date
      2016-05-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] SPR and ITC-based small-molecule screening to find inhibitors of protein-protein interaction2016

    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      DiPIA 2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Thermodynamic elucidation of binding process for protein-ligand interactions to propose a drug design2016

    • Author(s)
      Satoru Nagatoishi, Sou Yamaguchi, Kouhei Tsumoto
    • Organizer
      第10回バイオ関連化学シンポジウム
    • Place of Presentation
      石川県立音楽堂
    • Year and Date
      2016-09-07
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Calorimetric characterization of the interaction between an intrinsically disordered protein YB-1 and nucleic acids2016

    • Author(s)
      Satoru Nagatoishi, Yumiko Tanabe, Kouhei Tsumoto
    • Organizer
      CALCON2016
    • Place of Presentation
      Turtle Bay, Hawaii, USA
    • Year and Date
      2016-07-31
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Thermodynamics of the interaction between proteins and small compounds in drug discovery2016

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      分子研研究会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] 9F NMR and SPR Screening for the Development of an Inhibitor of the Tob1-CNOT7 Interaction2016

    • Author(s)
      Kouhei Soeda ,Satoru Nagatoishi, E. Kato, M. Yamamoto, Kouhei Tsumoto
    • Organizer
      The 27th International Conference on Magnetic Resonance in Biological Systems
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Tob1-CNOT7相互作用阻害剤開発を目指した19F-NMRスクリーニング2016

    • Author(s)
      副田 康平・長門石 曉、加藤 悦子、山本 雅、津本 浩平
    • Organizer
      第136年会 日本薬学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] SPR and ITC-based small-molecule screening to find inhibitors of protein-protein interactions.2016

    • Author(s)
      Satoru Nagatoishi, Tsumoto Kouhei
    • Organizer
      Developments in Protein Interaction Analysis 2016
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2016-06-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] 熱力学的解析を基盤とした茶カテキン-蛋白質間の分子認識機構の解明2016

    • Author(s)
      高橋知也、長門石曉、黒田大祐、津本浩平
    • Organizer
      第21回日本フードファクター学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Biophysical approach to find the inhibitors of CapF and ERK2 enzyme in FBDD.2016

    • Author(s)
      Satoru Nagatoishi, Tsumoto Kouhei
    • Organizer
      JCUP VII
    • Place of Presentation
      大手町サンスカイルーム, 東京
    • Year and Date
      2016-05-16
    • Data Source
      KAKENHI-PROJECT-16H04710
  • [Presentation] Thermodynamic analysis of molecular recognition between tea catechins and human serum albumin2016

    • Author(s)
      Sartoru Nagatoishi, Y. Tanabe, Kouhei Tsumoto
    • Organizer
      CALCON2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420
  • [Presentation] Biophysical cross-validation in fragment screening of fluorinated chemical library toward FBDD using SPR, ITC and 19F NMR2015

    • Author(s)
      Satoru Nagatoishi, Sou Yamaguchi, Keita Kajita, Etsuko Katoh, Hiroyuki Akiyama, Satoru Kanai, Toshio Furuya, Kouhei Tsumoto
    • Organizer
      The 43rd Symposium on Structural Activity Relationship 2015
    • Place of Presentation
      新潟日報メディアシップ日報ホール (新潟市)
    • Year and Date
      2015-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Screening of novel infection inhibitors targeting iron-uptake pathways against Group A streptococcus2015

    • Author(s)
      Masato Hoshino, Jose Manuel Martinez Caaveiro, Satoru Nagatoishi, Ichiro Nakagawa, Kouhei Tsumoto
    • Organizer
      第7回GSCシンポジウム
    • Place of Presentation
      一橋大学一橋講堂 他(国立市)
    • Year and Date
      2015-07-05
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Protein adsorption to Cyclo Olefin Polymer using reflectometric interference spectroscopy2015

    • Author(s)
      Satoru NAGATOISHI, Satoru ADACHI , Hiroya NISHIOKA, Kouhei TSUMOTO
    • Organizer
      第7回GSCシンポジウム
    • Place of Presentation
      一橋大学一橋講堂 他(国立市)
    • Year and Date
      2015-07-05
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Development of novel infection inhibitors targeting iron-uptake pathways against Group A streptococcus2015

    • Author(s)
      Masato Hoshino, Jose Manuel Martinez Caaveiro, Satoru Nagatoishi, Ichiro Nakagawa, Kouhei Tsumoto
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2015 (PacificChem)
    • Place of Presentation
      Hawaii convention center 他 (Honolulu, USA)
    • Year and Date
      2015-12-15
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] The protein-protein interactions in highly concentrated antibody solution investigated by Raman spectroscopy.2015

    • Author(s)
      太田 周志、長門石 曉、野口 慎太郎、津本 浩平
    • Organizer
      第53回日本生物物理学会年会
    • Place of Presentation
      金沢大学角間キャンパス(石川県金沢市)
    • Year and Date
      2015-09-13
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 低分子スクリーニングにおける熱量解析の活用2015

    • Author(s)
      長門石 曉
    • Organizer
      よこはまNMR研究会第53回ワークショップ
    • Place of Presentation
      理化学研究所横浜事業所 (横浜市)
    • Year and Date
      2015-09-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] 含フッ素フラグメントライブラリを用いた19F NMR、SPR、ITCによるスクリーニング2015

    • Author(s)
      山口奏・長門石曉・梶谷敬太・加藤悦子・秋山弘行・金井理・古谷利夫・津本浩平
    • Organizer
      第6回 スクリーニング学研究会
    • Place of Presentation
      ソニックシティ(大宮市)
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Biophysical cross-validation in fragment screening of fluorinated chemical library toward FBDD using SPR, ITC and 19F NMR2015

    • Author(s)
      Satoru Nagatoishi、Sou Yamaguchi、Keita Kajita、Etsuko Katoh、Hiroyuki Akiyama、Satoru Kanai、Toshio Furuya、Kouhei Tsumoto
    • Organizer
      The 43rd Symposium on Structural Activity Relationship 2015 The 10th Japan-China Joint Symposium on Drug Discovery and Development
    • Place of Presentation
      新潟日報メディアシップ日報ホール(新潟県新潟市)
    • Year and Date
      2015-09-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] Elucidation of transition state for the interactions between ERK2 and inhibitors using SPR2015

    • Author(s)
      山口奏・長門石曉・津本浩平
    • Organizer
      CBI学会2015年大会
    • Place of Presentation
      タワーホール船堀(江戸川区)
    • Year and Date
      2015-10-27
    • Data Source
      KAKENHI-PROJECT-15K17882
  • [Presentation] Structural and mechanistic basis of capsular polysaccharide-synthesizing enzymes CapE/CapF, and the route to discovery novel inhibitors with antibacterial properties2015

    • Author(s)
      Jose M.M. Caaveiro、Takamistsu Miyafusa、Takeru Chigira、Koichiro Nakano、Satoru Nagatoishi、Kouhei Tsumoto
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2015 (PacificChem)
    • Place of Presentation
      Honolulu, Hawaii(U.S.A.)
    • Year and Date
      2015-12-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 低分子スクリーニングにおける熱量解析の活用2015

    • Author(s)
      長門石 曉
    • Organizer
      よこはまNMR研究会 第53 回ワークショップ
    • Place of Presentation
      理化学研究所横浜事業所(神奈川県横浜市鶴見区)
    • Year and Date
      2015-09-16
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 癌関連蛋白質Y-box binding protein 1の物理化学的手法を用いた機能解析2014

    • Author(s)
      田邊裕美子、長門石曉、西方敬人、杉本直己、津本 浩平
    • Organizer
      第13回 日本蛋白質科学会年会
    • Place of Presentation
      とりぎん文化会館(鳥取市)
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] 生命分子相互作用解析 : ITCとSPR2014

    • Author(s)
      長門石曉・津本浩平
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      くまもと県民交流会館パレアホール(熊本県熊本市)
    • Year and Date
      2014-03-30
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] 生命分子相互作用解析:ITC とSPR2014

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      くまもと県民交流会館パレアホール(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] フラグメントライブラリーによる莢膜合成酵素CapFの阻害剤探索2013

    • Author(s)
      中納広一郎、宮房孝光、長門石曉、Jose Caaveiro、津本浩平
    • Organizer
      第4回スクリーニング学研究会
    • Place of Presentation
      東京大学伊藤謝恩ホール(東京都文京区)
    • Year and Date
      2013-11-29
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 天然変性型蛋白質の機能制御へ向けた核酸結合蛋白質YB-1の物理化学的解析2013

    • Author(s)
      長門石曉、田邊 裕美子、西方 敬人、杉本 直己、津本 浩平
    • Organizer
      第7回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋大学東山キャンパス(愛知県名古屋市)
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] Physicochemical studies of YB-1 functions and structures2013

    • Author(s)
      Satoru Nagatoishi, Yumiko Tanabe, Kouhei Tsumoto
    • Organizer
      Biophysical Society 58th Annual Meeting
    • Place of Presentation
      Moscone Center (San Francisco, CA)
    • Year and Date
      2013-02-18
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] 分子間相互作用をミクロに捕らえる表面プラズモン共鳴法と熱測定の活用2013

    • Author(s)
      長門石曉・津本浩平
    • Organizer
      第17回コロイド・界面フォーラム
    • Place of Presentation
      KKR江の島ニュー向洋(神奈川県藤沢市)
    • Year and Date
      2013-07-18
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] Y-box binding protein 1(YB-1)の物性とDNA結合メカニズムの解析2013

    • Author(s)
      田邊裕美子・長門石曉・西方敬人・杉本直己・津本浩平
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学びわこ・くさつキャンパス(草津市)
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] 分子間相互作用をミクロに捕らえる表面プラズモン共鳴法と熱測定の活用2013

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第17回コロイド・界面フォーラム
    • Place of Presentation
      KKR江の島ニュー向洋(神奈川県藤沢市)
    • Year and Date
      2013-07-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 癌関連蛋白質Y-box binding protein 1の物理化学的手法を用いた機能解析2013

    • Author(s)
      田邊裕美子・長門石曉、西方敬人、杉本直己、津本浩平
    • Organizer
      第13回日本蛋白質科学会年会
    • Place of Presentation
      とりぎん文化会館(鳥取市)
    • Year and Date
      2013-06-12
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] 病原性細菌のHeme輸送システムを阻害する低分子化合物の探索2013

    • Author(s)
      長門石曉、下村拓矢、安部良太、星野将人、Jose Caaveiro、津本浩平
    • Organizer
      第4回スクリーニング学研究会
    • Place of Presentation
      東京大学伊藤謝恩ホール(東京都文京区)
    • Year and Date
      2013-11-29
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] Y-box binding protein 1(YB-1)の物性とDNA結合メカニズムの解析2013

    • Author(s)
      田邊裕美子、長門石曉、西方敬人、杉本直己、津本浩平
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      滋賀
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] 細胞接着蛋白質P-cadherinの同種親和的二量体形成機構の解明2013

    • Author(s)
      工藤 翔太,ホセ カアベイロ,長門石 暁,浜窪 隆雄,児玉 龍彦,松浦 正,須藤 幸夫,津本 浩平
    • Organizer
      第86回日本生化学学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2013-09-12
    • Data Source
      KAKENHI-PROJECT-25220205
  • [Presentation] 熱力学的相互作用解析と分子動力学シミュレーションによる抗体の親和性向上のメカニズムの研究2013

    • Author(s)
      渡部 貴大,長門石 曉,山下 雄史,中山 泰亮,溝端 栄一,浜窪 隆雄,井上 豪,津本 浩平,児玉 龍彦,藤谷 秀章
    • Organizer
      第36回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2013-12-03
    • Data Source
      KAKENHI-PROJECT-25220205
  • [Presentation] 天然変性型蛋白質の機能制御へ向けた核酸結合蛋白質YB-1の物理化学的解析2013

    • Author(s)
      長門石曉・田邊裕美子・西方敬人・杉本直己・津本浩平
    • Organizer
      第7回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋大学東山キャンパス(愛知県名古屋市)
    • Year and Date
      2013-09-28
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] 逆ミセル中におけるテロメア配列DNAの四重鎖形成2012

    • Author(s)
      Pramanik Smritimoy・長門石暁・杉本直己
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Y-box結合タンパク質YB-1の核酸結合解析2012

    • Author(s)
      長門石暁・西方敬人・杉本直己
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Thermodynamics and hydration effects on the interaction between DNA G-quadruplex and thrombin2012

    • Author(s)
      Satoru Nagatoishi, Naoki Sugimoto
    • Organizer
      The Second Asian Chemical Biology Conference, ACBC2012
    • Place of Presentation
      Okinawa (Japan)
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] Thermodynamics and hydration effects on the interaction between DNA G-quadruplex and thrombin2012

    • Author(s)
      Satoru Nagatoishi, Naoki Sugimoto
    • Organizer
      The Second Asian Chemical Biology Conference, ACBC2012
    • Place of Presentation
      Okinawa
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] Effects of a thymine residue deletion in TT loops on thrombin-‐TBA recognition interactions: a crystallographic study2012

    • Author(s)
      Irene Russo Krauss, Andrea Pica, Antonello Merlino, Satoru Nagatoishi, Naoki Sugimoto, Lelio Mazzarella and Filomena Sica
    • Organizer
      CONFORMATIONAL DIVERSITY AND APPLICATIONS OF G-QUADRUPLEXES
    • Place of Presentation
      Barcelona (Spain)
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] Effects of a thymine residue deletion in TT loops on thrombin-‐TBA recognition interactions : a crystallographic study2012

    • Author(s)
      Irene Russo Krauss, Andrea Pica, Antonello Merlino, Satoru Nagatoishi, Naoki Sugimoto, Lelio Mazzarella and Filomena Sica
    • Organizer
      CONFORMATIONAL DIVERSITY AND APPLICATIONS OF G-QUADRUPLEXES
    • Place of Presentation
      Spain
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] RNAのhairpin構造形成による転写活性変化2011

    • Author(s)
      小野領也・長門石曉・杉本直己
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      茨城
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Effect of Loop residues of thrombin-binding DNA aptamer on its G-quadruplex stability and thrombin binding2011

    • Author(s)
      S.Nagatoishi, N.Isono, N.Sugimoto
    • Organizer
      4th European Conference on Chemistry for Life Sciences
    • Place of Presentation
      Budapest, Hungary
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Role of hydration effect in interaction between DNA G-quadruplex and thrombin2011

    • Author(s)
      S. Nagatoishi, N. Isono and N. Sugimoto
    • Organizer
      The 38th International Symposium on Nucleic Acids Chemistry 2011
    • Place of Presentation
      Hokkaido
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] DNA-RNAハイブリッド二重鎖の構造柔軟性に関連した水和変化2011

    • Author(s)
      長門石暁・Pramanik Smritimoy・Saxena Sarika・Bhatacharyya Jhimli・杉本直己
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] RNAのhairpin構造形成による転写活性変化2011

    • Author(s)
      小野領也・長門石暁・杉本直己
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Effect of Loop residues of thrombin-binding DNA aptamer on its G-quadruplex stability and thrombin binding2011

    • Author(s)
      S. Nagatoishi, N. Isono, and N. Sugimoto
    • Organizer
      4th European Conference on Chemistry for Life Sciences
    • Place of Presentation
      Hungary
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Thrombin結合によるDNA四重鎖構造の安定化メカニズムの解明2011

    • Author(s)
      長門石曉・磯野伸・津本浩平・杉本直己
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Role of hydration effect in interaction betweenDNA G-quadruplex and thrombin2011

    • Author(s)
      S.Nagatoishi, N.Isono, N.Sugimoto
    • Organizer
      The 38th International Symposium on Nucleic Acids Chemistry 2011
    • Place of Presentation
      Clark Hall, Hokkaido University, Hokkaido
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Formation of DNA G-quadruplex structures in water-in-oil reverse microemulsion2011

    • Author(s)
      S.Pramanik, S.Nagatoishi, N.Sugimoto
    • Organizer
      The 38th International Symposium on Nucleic Acids Chemistry 2011
    • Place of Presentation
      Clark Hall, Hokkaido University, Hokkaido
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] DNA G-quadruplexformation with its binding protein in crowded environment2010

    • Author(s)
      S. Nagatoishi, N. Isono, K. Tsumoto, and N. Sugimoto
    • Organizer
      The 37th International Symposium on Nucleic Acids Chemistry 2010
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Comparative study for the effects of cation and thrombin on the thermal stabilization of G-quadruplex2010

    • Author(s)
      N.Isono, S.Nagatoishi, M.Kudou, K.Tsumoto, N.Sugimoto
    • Organizer
      The 37th International Symposium on Nucleic Acids Chemistry 2010
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] タンパク質と四重鎖DNAの相互作用における分子クラウディング効果2010

    • Author(s)
      長門石曉・磯野伸・津本浩平・杉本直己
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] G-quadruplex stability in the presence of its binding protein under a molecular crowding condition2010

    • Author(s)
      S.Nagatoishi, N.Isono, N.Sugimoto
    • Organizer
      IRT 2010-XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids Lyon
    • Place of Presentation
      France
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] G-quadruplex stability in the presence of its binding protein under a molecular crowding condition2010

    • Author(s)
      S. Nagatoishi, N. Isono, and N. Sugimoto
    • Organizer
      IRT 2010-XIX International Round Table on Nucleosides
    • Place of Presentation
      France
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] RNAサイレンシング関連蛋白質の核酸結合における溶媒効果2010

    • Author(s)
      長門石曉・杉本直己
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22655057
  • [Presentation] Protein shackle: A polymerizing scaffold for functional protein

    • Author(s)
      Ryo Matsunaga, Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      5th Annual PEGS Europe
    • Place of Presentation
      Sheraton Lisboa Hotel & Spa (ポルトガル/リスボン)
    • Year and Date
      2013-11-04 – 2013-11-08
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 分子間相互作用をミクロに捕らえる 表面プラズモン共鳴法と熱測定の活用

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第17回コロイド・界面フォーラム
    • Place of Presentation
      KKR江の島ニュー向洋(神奈川県藤沢市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24750166
  • [Presentation] 化膿レンサ球菌由来Shr、Shpによるヘム輸送機構の物理化学的解析

    • Author(s)
      星野将人、Caaveiro Jose、長門石曉、中川一路、津本 浩平
    • Organizer
      第8回バイオ関連化学シンポジウム
    • Place of Presentation
      岡山大学(岡山県岡山市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] プロテオグリカンOsteomodulinの物理化学的解析

    • Author(s)
      田島卓実、中木戸誠、長門石曉、大沼信一、津本浩平
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学東山キャンパス( 愛知県名古屋市)
    • Year and Date
      2014-03-27 – 2014-03-30
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 機能制御を目指した疾患関連蛋白質Mint3の物性解析

    • Author(s)
      中山佳昭、田代晋也、長門石曉、坂本毅治、清木元治、津本浩平
    • Organizer
      第14回日本蛋白質科学会
    • Place of Presentation
      ワークピア横浜(神奈川県横浜市)
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 黄色ブドウ球菌由来の莢膜合成酵素CapFに結合する低分子化合物の解析

    • Author(s)
      長門石曉、中納 広一郎、宮房 孝光、Caaveiro Jose、津本 浩平
    • Organizer
      第8回バイオ関連化学シンポジウム
    • Place of Presentation
      岡山大学(岡山県岡山市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 骨石灰化機構に関するプロテオグリカンOsteomodulinの物性解析

    • Author(s)
      田島卓実、長門石曉、Caaveiro Jose、工藤翔太、中木戸誠、大沼信一、津本浩平
    • Organizer
      第8回バイオ関連化学シンポジウム
    • Place of Presentation
      岡山大学(岡山県岡山市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 生命分子相互作用解析:ITC とSPR

    • Author(s)
      長門石曉、津本浩平
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      くまもと県民交流会館パレアホール(熊本県熊本市)
    • Year and Date
      2014-03-27 – 2014-03-30
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 乳癌関連蛋白質BIG3とPHB2の物性解析

    • Author(s)
      千吉良岳、長門石曉、片桐豊雅、津本浩平
    • Organizer
      第14回日本蛋白質科学会
    • Place of Presentation
      ワークピア横浜(神奈川県横浜市)
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] Staphylococcus aureus莢膜合成酵素CapFと低分子化合物の物理化学的な相互作用解析

    • Author(s)
      長門石曉、中納 広一郎、宮房 孝光、Caaveiro Jose、津本 浩平
    • Organizer
      第42回構造活性相関シンポジウム
    • Place of Presentation
      くまもと森都心プラザ(熊本県熊本市)
    • Year and Date
      2014-11-13 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 黄色ブドウ球菌由来莢膜合成酵素CapF の補酵素取り込み機構に関する熱量解析

    • Author(s)
      中納広一郎、宮房孝光、Jose Manuel Martinez Caaveiro、長門石曉、津本浩平
    • Organizer
      第13回日本蛋白質科学会年会
    • Place of Presentation
      とりぎん文化会館(鳥取県鳥取市)
    • Year and Date
      2013-06-12 – 2013-06-14
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 多機能性タンパク質PHB2のフォールディング状態に対する疎水環境の影響

    • Author(s)
      Takeru Chigira、Satoru Nagatoishi, Toyomasa Katagiri, Kouhei Tsumoto
    • Organizer
      第52回日本生物物理学会年会(BSJ2014)
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] Biophysical Approach of Fragment Screening to inhibit the heme transfer system of Pathogenic bacteria

    • Author(s)
      Satoru Nagatoishi, Takuya Shimomura, Ryota Abe, Masato Hoshino, Jose Caaveiro, Kouhei Tsumoto
    • Organizer
      CBI学会2013年大会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2013-10-28 – 2013-10-31
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] Inhibitor Screening of Capsular Polysaccharide Synthesizing Enzyme CapF from Staphylococcus aureus

    • Author(s)
      Koichiro Nakano, Takamitsu Miyafusa, Satoru Nagatoishi, Jose Caaveiro, Kouhei Tsumoto
    • Organizer
      CBI学会2013年大会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2013-10-28 – 2013-10-31
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 特異的分子認識により重合する蛋白質の設計とその応用

    • Author(s)
      松長遼、長門石曉、津本浩平
    • Organizer
      第14回日本蛋白質科学会
    • Place of Presentation
      ワークピア横浜(神奈川県横浜市)
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 多機能性タンパク質PHB2の物性解析

    • Author(s)
      千吉良岳、長門石曉、片桐豊雅、津本浩平
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学東山キャンパス( 愛知県名古屋市)
    • Year and Date
      2014-03-27 – 2014-03-30
    • Data Source
      KAKENHI-PROJECT-25249115
  • [Presentation] 還元環境に応答して重合する蛋白質Protein shackleの開発

    • Author(s)
      松長遼、長門石曉、津本浩平
    • Organizer
      第8回バイオ関連化学シンポジウム
    • Place of Presentation
      岡山大学(岡山県岡山市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25249115
  • []

  • 1.  Tsumoto Kouhei (90271866)
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  • 24.  SAKAMOTO Takeharu
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  • 27.  TATEISHI Hisae
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  • 28.  MURAOKA Takahiro
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  • 29.  林 智彦
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  • 30.  金原 数
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  • 52.  松村 浩由
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