Sumikama Takashi 炭竈享司

Researcher Number	30579412
Other IDs	https://orcid.org/0000-0003-3696-5720
Affiliation (Current)	2025: 京都大学, 生命科学研究科, 特定講師 2025: 金沢大学, ナノ生命科学研究所, 特任助教
Affiliation (based on the past Project Information) *help	2024: 金沢大学, ナノ生命科学研究所, 特任助教 2019: 金沢大学, ナノ生命科学研究所, 特任助教 2018: 金沢大学, ナノ生命科学研究所, 博士研究員 2017: 福井大学, 学術研究院医学系部門, 特命助教 2014 – 2016: 福井大学, 医学部, 特命助教
Review Section/Research Field	Principal Investigator Basic Section 28040:Nanobioscience-related / Biophysics / Physical chemistry Except Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / General physiology
Keywords	Principal Investigator 分子動力学 / シミュレーション / 分子動力学法 / イオンチャネル / 原子間力顕微鏡 / 多量体形成 / チャネル / トキシン / 膜挿入 / 相互作用 … More / 膜 / タンパク質 / 細胞膜 / モデルチャネル / イオン選択性 / イオン透過 … More Except Principal Investigator イオンチャネル / 分子動力学計算 / 電気生理 / 構造解析 / イオン選択性 / 原子間力顕微鏡 / 膜蛋白質 / 生理学 / 走査プローブ顕微鏡 / 蛋白質 / ゲーティング / 集合・離散 / 細胞膜 / チャネル / channel gating / clustering / membrane lipid / single-channel current / lipid bilayer Less

Theoretical development of simultaneous measurements of molecular structure and dynamics using atomic force microscopy and its application to real moleculesPrincipal Investigator
- Principal Investigator
  
  炭竈享司
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  Kanazawa University
The master of ion selectivity of ion channels
- Principal Investigator
  
  入江克雅
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Wakayama Medical University
Elucidation of polymerization mechanism of ion channels and its physiological significancePrincipal Investigator
- Principal Investigator
  
  Sumikama Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Kanazawa University
  University of Fukui
Mechanism underlying the clustering-dispersion dynamics of the channel protein on the membrane
- Principal Investigator
  
  Oiki Shigetoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  University of Fukui
Development of a theory to describe ion permeation and selectivity through potassium channelsPrincipal Investigator
- Principal Investigator
  
  Sumikama Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical chemistry
- Research Institution
  University of Fukui

All 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Computing Atomic Force Microscopy Images of Chromosomes using Polymer Simulation2020
- Author(s)
  Sumikama Takashi、Foster Adam S.、Fukuma Takeshi
- Journal Title
  
  Biophysical Journal
  
  Volume: 118 Issue: 3 Pages: 619a-619a
- DOI
  10.1016/j.bpj.2019.11.3341
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768
[Journal Article] Induced-Fit Pathway Accelerated Binding of Agitoxin-2 to A K+ Channel Imaged by HS-AFM2020
- Author(s)
  Sumino Ayumi、Sumikama Takashi、Uchihashi Takayuki、Oiki Shigetoshi
- Journal Title
  
  Biophysical Journal
  
  Volume: 118 Issue: 3 Pages: 236a-236a
- DOI
  10.1016/j.bpj.2019.11.1392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17768
[Journal Article] Computed Atomic Force Microscopy Images of Chromosomes by Calculating Forces with Oscillating Probes2019
- Author(s)
  Sumikama Takashi、Foster Adam. S.、Fukuma Takeshi
- Journal Title
  
  The Journal of Physical Chemistry C
  
  Volume: 124 Issue: 3 Pages: 2213-2218
- DOI
  10.1021/acs.jpcc.9b10263
- NAID
  120006780310
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02111, KAKENHI-PROJECT-17K17768
[Journal Article] Queueing arrival and release mechanism for K+ permeation through a potassium channel2019
- Author(s)
  Takashi Sumikama, Shigetoshi Oiki
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 69 Pages: 919-930
- NAID
  120006715810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17768
[Journal Article] High-speed AFM reveals accelerated binding of agitoxin-2 to a K+ channel by induced fit2019
- Author(s)
  A. Sumino,T. Sumikama,T. Uchihashi,S. Oiki
- Journal Title
  
  Science Advances
  
  Volume: 5 Issue: 7 Pages: 1-10
- DOI
  10.1126/sciadv.aax0495
- NAID
  120006649788
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19422, KAKENHI-PROJECT-19K22382, KAKENHI-PUBLICLY-19H05389, KAKENHI-PROJECT-17H04017, KAKENHI-PROJECT-17K17768, KAKENHI-PROJECT-17H05058
[Journal Article] Origins of Heat Evolution in Mixing Water and Dimethyl Sulfoxide2018
- Author(s)
  Mizuno Kazuko、Sumikama Takashi、Tarnai Yoshinori、Tani Masahiko
- Journal Title
  
  International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz2018)
  
  Volume: － Pages: 1-2
- DOI
  10.1109/irmmw-thz.2018.8509894
- NAID
  120006602138
- Data Source
  KAKENHI-PROJECT-17K17768
[Journal Article] Structure and dynamics of solvent molecules inside the polytheonamide B channel in different environments: a molecular dynamics study2018
- Author(s)
  Kalathingal Mahroof、Sumikama Takashi、Mori Toshifumi、Oiki Shigetoshi、Saito Shinji
- Journal Title
  
  Physical Chemistry Chemical Physics
  
  Volume: 20 Issue: 5 Pages: 3334-3348
- DOI
  10.1039/c7cp06299k
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768, KAKENHI-PUBLICLY-16H00759, KAKENHI-PUBLICLY-16H00856, KAKENHI-PROJECT-16H02254, KAKENHI-PROJECT-17H04017, KAKENHI-PROJECT-16K15179, KAKENHI-PROJECT-15K17813
[Journal Article] Entrance of Channel Determines Ion Permeation Rate through the Kv1.2 Channel2018
- Author(s)
  炭竈享司、老木成稔
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 58 Issue: 1 Pages: 012-016
- DOI
  10.2142/biophys.58.012
- NAID
  130006322043
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17768, KAKENHI-PUBLICLY-16H00759, KAKENHI-PROJECT-17H04017, KAKENHI-PROJECT-16K15179
[Journal Article] Capturing the Freeze-Drying Dynamics of NaCl Nanoparticles Using THz Spectroscopy2018
- Author(s)
  Ajito Katsuhiro、Ueno Yuko、Kim Jae-Young、Sumikama Takashi
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 140 Issue: 42 Pages: 13793-13797
- DOI
  10.1021/jacs.8b07828
- NAID
  120006602137
- Data Source
  KAKENHI-PROJECT-17K17768
[Journal Article] Origin of the shape of Current-Voltage Curve through Nanopores: A Molecular Dynamics Study2016
- Author(s)
  Takashi Sumikama
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 25750-25750
- DOI
  10.1038/srep25750
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870232
[Journal Article] Visualization of fluctuating motions of the selectivity filter in the potassium channel: A computational study2015
- Author(s)
  Takashi Sumikama and Shigetoshi Oiki
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870232
[Journal Article] Structure and Dynamics of Membrane-embedded KcsA Potassium Channel Revealed by Atomic Force Microscopy2015
- Author(s)
  角野歩、山本大輔、炭竃享司、岩本真幸、出羽毅久、老木成稔
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 55 Issue: 1 Pages: 005-010
- DOI
  10.2142/biophys.55.005
- NAID
  130004794734
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26102516, KAKENHI-PROJECT-26870232, KAKENHI-PROJECT-26870233, KAKENHI-PROJECT-26253014
[Journal Article] Channel Function Reconstitution and Re-animation: A Single-channel Strategy in the Post-crystal Age.2015
- Author(s)
  Oiki, S.
- Journal Title
  
  J. Physiol.
  
  Volume: 593 Issue: 12 Pages: 2553-2573
- DOI
  10.1113/jp270025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26102516, KAKENHI-PROJECT-26253014
[Presentation] Computing Atomic Force Microscopy Images of Chromosomes Using Polymer Simulation2020
- Author(s)
  Takashi Sumikama, Adam. S. Foster, Takeshi Fukuma
- Organizer
  Biophysical Society 64th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Toward elucidating a relation between computed atomic force microscopy image and actual structure using machine learning2020
- Author(s)
  Takashi Sumikama, Niko Oinonen, Fedor Urtev, Adam. S. Foster, Takeshi Fukuma
- Organizer
  The 1st International Conference on Big Data and Machine Learning in Microscopy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] KcsA K+チャネルでのイオン選択性の分子機構2020
- Author(s)
  炭竈享司、三田建一郎、老木成
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] 3D-AFM像の理論予測とHS-AFMの動画解析2019
- Author(s)
  炭竈享司
- Organizer
  第2回CREST会議（研究課題名：高速原子間力顕微鏡１分子計測のデータ同化による生体分子4次元構造解析法の開発）
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] 分子シミュレーションで見る毒の作用機序：海綿由来毒ポリセオナミドの細胞膜への挿入2019
- Author(s)
  炭竈享司、Mahroof Kalathingal、老木成稔、斉藤真司
- Organizer
  トキシンシンポジウム
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] 間期と分裂期の染色体の3D-AFM像の理論的予測2019
- Author(s)
  炭竈享司、宮澤佳甫、Adam S. Foster、福間剛士
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] 染色体の3D-AFM像の理論予測2019
- Author(s)
  炭竈享司、福間剛士
- Organizer
  生物物理学会中部支部会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] 染色体の3D-AFM像と実像の関係の理論的解明2019
- Author(s)
  炭竈享司、宮澤佳甫、Adam S. Foster、福間剛士
- Organizer
  日本生物物理学会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Computational prediction of 3D-AFM images of chromosomes2019
- Author(s)
  炭竈享司
- Organizer
  Joint UBI-NanoLSI workshop "Trends in Molecular Biophysics of Living Cells"
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] KcsAチャネルでのK+とNa+の選択的透過のMDシミュレーションによる再現2018
- Author(s)
  炭竈享司
- Organizer
  第3回イオンチャネル研究会チャネルフェニックス
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Na+イオンはKcsA K+チャネルを遅いが透過する2018
- Author(s)
  炭竈享司、三田建一郎、老木成稔
- Organizer
  日本生物物理学会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] K+チャネルでのイオンの透過と選択性の誤謬：どこで何を間違えたか？2018
- Author(s)
  炭竈享司
- Organizer
  蛋白研研究会「構造情報に基づいた膜イオン輸送タンパク質の生理機能の解明に向けて」
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Computational modeling of chromosomes and carbon nanotubes as a probe of atomic force microscopy2018
- Author(s)
  炭竈享司、宮澤佳甫、日笠山拓、中山響介、原田昌征、福間剛士
- Organizer
  Biophysical Society Thematic Meeting on the Genome Biophysics: Integrating Genomics and Biophysics to Understand Structural and Functional Aspects of Genomes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Towards elucidating the physical origin of force in AFM measurements and a method analyzing dynamics observed by HS-AFM2018
- Author(s)
  炭竈享司
- Organizer
  WPI-NanoLSI workshop "Trends in Computational Molecular Biophysics"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] 分布関数の時間発展で生体内現象を解析する：K+チャネルにおけるイオン透過を例に2017
- Author(s)
  炭竈享司
- Organizer
  第16回計算分子化学コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] An alternative permeation mechanism through the K+ channel2017
- Author(s)
  炭竈享司、老木成稔
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] K+チャネルでのイオン透過におけるイオンと水分子の相互作用の重要性2017
- Author(s)
  炭竈享司
- Organizer
  第2回イオンチャネル研究会チャネル七夕
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Knock-on is not a canonical mechanism for K+ permeation through potassium channels2017
- Author(s)
  炭竈享司、老木成稔
- Organizer
  アメリカ生物物理学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] イオンチャネルを通るイオン透過における水分子の役割：モデルチャネルとK+チャネルを例に2017
- Author(s)
  炭竈享司
- Organizer
  福井大学遠赤外領域開発研究センターセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] K+チャネルを通る電流のMichaelis-Menten様の飽和の分子論的説明2017
- Author(s)
  炭竈享司、老木成稔
- Organizer
  分子シミュレーション討論会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Water orientation in nanocavity of the Kv1.2 channel and its role in ion permeation: A molecular dynamics study2017
- Author(s)
  炭竈享司
- Organizer
  Workshop on Reaction and Structural Dynamics in Condensed Phases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] イオンチャネルにおけるノックオン機構は本当に重要か？ーその2ー2017
- Author(s)
  炭竈享司、老木成稔
- Organizer
  生物物理学会中部支部会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] イオンチャネルでのイオン透過を分布関数の時間発展で捉える2017
- Author(s)
  炭竈享司、老木成稔
- Organizer
  理論化学討論会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] 何がK+チャネルでのイオンの透過速度を決めるか？：分子動力学シミュレーションによる研究2017
- Author(s)
  炭竈享司
- Organizer
  ナノ計測勉強会2017
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] 計算科学は膜イオン輸送の実験をどこまで再現できるか？：K+チャネルでのイオン透過2017
- Author(s)
  炭竈享司
- Organizer
  蛋白研研究会「膜イオン輸送の学際研究：計算科学から医学まで」
- Invited
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Spontaneous exits of ions from the KcsA channel2017
- Author(s)
  炭竈享司、老木成稔
- Organizer
  日本生物物理学会
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Is Knock-on the Canonical Mechanism for the Ion Permeation through a Potassium Channel?2017
- Author(s)
  炭竈享司、老木成稔
- Organizer
  新学術領域研究「動的秩序と機能」第6回国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17768
[Presentation] Bridging ion permeation and ion selectivity through K+ channel2016
- Author(s)
  炭竈享司、三田建一郎、老木成稔
- Organizer
  日本生理学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26870232
[Presentation] Visualization of fluctuating motions of the selectivity filter in the potassium channel: A computational study2015
- Author(s)
  炭竈享司, 老木成稔
- Organizer
  日本生理学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26870232
[Presentation] Difference in ion permeation mechanism through the Kv1.2 and KcsA channels: A molecular dynamics study2015
- Author(s)
  Takashi Sumikama and Shigetoshi Oiki
- Organizer
  The International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Hawaii Convention Center
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870232
[Presentation] A kinetic model describing punch-through of Na+ through KcsA potassium channel; イオン透過と選択性を記述する速度論モデル2015
- Author(s)
  炭竈享司、三田建一郎、老木成稔
- Organizer
  日本生物物理学会
- Place of Presentation
  金沢大学角間キャンパス
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-26870232
[Presentation] Kv1.2でのイオン透過における透過パターンの解析2014
- Author(s)
  炭竈享司, 斉藤真司, 老木成稔
- Organizer
  日本生物物理学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26870232
[Presentation] Fluctuation of carbonyl backbone of the selectivity filter of the Kv1.2 channel during K+ permeation2014
- Author(s)
  炭竈享司, 老木成稔
- Organizer
  The 45th NIPS Internaional Symposium, co-sponsored by The Journal of Physiology "Cutting-edge approaches towards the functioning mechanisms of membrane proteins"
- Place of Presentation
  岡崎コンファレンスセンター
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26870232
[Presentation] The Ratio of Flux of Water Molecules over that of Ions through Ion Channel Reflects Interactions between Channel and Ions2014
- Author(s)
  炭竈享司
- Organizer
  OIST Workshops "Single Protein Dynamics in Cellulo 2014: Spatio-Temporal, Structural and Quantitative Analyses"
- Place of Presentation
  OIST, 沖縄
- Year and Date
  2014-04-21
- Data Source
  KAKENHI-PROJECT-26870232

1. Oiki Shigetoshi (10185176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 岩本真幸 (40452122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 角野歩 (80717140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 宮澤佳甫 (40845525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 入江克雅 (20415087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUKUMA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sumikama Takashi 炭竈 享司

Research Projects

Research Products

Co-Researchers

Theoretical development of simultaneous measurements of molecular structure and dynamics using atomic force microscopy and its application to real moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The master of ion selectivity of ion channels

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of polymerization mechanism of ion channels and its physiological significancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism underlying the clustering-dispersion dynamics of the channel protein on the membrane

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a theory to describe ion permeation and selectivity through potassium channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Computing Atomic Force Microscopy Images of Chromosomes using Polymer Simulation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induced-Fit Pathway Accelerated Binding of Agitoxin-2 to A K+ Channel Imaged by HS-AFM2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computed Atomic Force Microscopy Images of Chromosomes by Calculating Forces with Oscillating Probes2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Queueing arrival and release mechanism for K+ permeation through a potassium channel2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] High-speed AFM reveals accelerated binding of agitoxin-2 to a K+ channel by induced fit2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Origins of Heat Evolution in Mixing Water and Dimethyl Sulfoxide2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Structure and dynamics of solvent molecules inside the polytheonamide B channel in different environments: a molecular dynamics study2018

Author(s)

Journal Title

DOI

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[Journal Article] Entrance of Channel Determines Ion Permeation Rate through the Kv1.2 Channel2018

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Sumikama Takashi 炭竈享司