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Irie Katsumasa  入江 克雅

Researcher Number 20415087
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-8178-1552
Affiliation (Current) 2021: 和歌山県立医科大学, 薬学部, 准教授
2021: 名古屋大学, 細胞生理学研究センター, 助教
Affiliation (based on the past Project Information) *help 2015 – 2020: 名古屋大学, 細胞生理学研究センター, 助教
Review Section/Research Field
Principal Investigator
Biophysics / General physiology / Basic Section 55050:Anesthesiology-related
Except Principal Investigator
Biophysics / Biological Sciences
Keywords
Principal Investigator
構造解析 / イオンチャネル / X線結晶構造解析 / イオン選択性 / 電気生理学 / 構造生理学 / 構造活性相関 / 局所麻酔薬 / ナトリウムチャネル / 構造機能相関 … More
Except Principal Investigator
… More クライオ電子顕微鏡 / 構造生理学 / チャネル / 膜タンパク質 / 単粒子解析 / 結晶学 / 構造生物学 / 単粒子解析法 / 膜タンパク質の生理機能 / 電子線結晶学 / 上皮バリア / タイトジャンクション / クローディン / TJ-アピカル複合体 / アピカル細胞骨格 Less
  • Research Projects

    (4 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (17 People)
  •  極低温電子顕微鏡を用いた単粒子解析による局所麻酔薬の結合阻害機構の解明Principal InvestigatorOngoing

    • Principal Investigator
      入江 克雅
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Nagoya University
  •  Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriersOngoing

    • Principal Investigator
      月田 早智子
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Structural and functional analysis of sodium selective permeation of voltage dependent sodium channelPrincipal Investigator

    • Principal Investigator
      Irie Katsumasa
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
      General physiology
    • Research Institution
      Nagoya University
  •  Studies in structural physiology of channels

    • Principal Investigator
      FUJIYOSHI Yoshinori
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biophysics
    • Research Institution
      Tokyo Medical and Dental University
      Nagoya University

All 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence.2020

    • Author(s)
      Shimomura Takushi、Yonekawa Yoshiki、Nagura Hitoshi、Tateyama Michihiro、Fujiyoshi Yoshinori、Irie Katsumasa
    • Journal Title

      eLife

      Volume: 9 Pages: 1-21

    • DOI

      10.7554/elife.52828

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17K08557, KAKENHI-PROJECT-17K17795
  • [Journal Article] Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression.2019

    • Author(s)
      Kamiya Atsunori、Hayama Yohsuke、Kato Shigeki、Shimomura Akihiko、Shimomura Takushi、Irie Katsumasa、Kaneko Ryosuke、Yanagawa Yuchio、Kobayashi Kazuto、Ochiya Takahiro
    • Journal Title

      第78回日本癌学会学術総会

      Volume: 22 Pages: 1289-1305

    • DOI

      10.1038/s41593-019-0430-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K22474, KAKENHI-PROJECT-18K16408, KAKENHI-PUBLICLY-18H04707, KAKENHI-PUBLICLY-19H04895, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-17H04365, KAKENHI-PROJECT-18K19950, KAKENHI-PROJECT-17K17795, KAKENHI-PROJECT-15KK0331
  • [Journal Article] Morphologic determinant of tight junctions revealed by claudin-3 structures.2019

    • Author(s)
      Nakamura Shun、Irie Katsumasa、Tanaka Hiroo、Nishikawa Kouki、Suzuki Hiroshi、Saitoh Yasunori、Tamura Atsushi、Tsukita Sachiko、Fujiyoshi Yoshinori
    • Journal Title

      Nat Commun.

      Volume: 10 Pages: 255-274

    • DOI

      10.1038/s41467-019-08760-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K17795, KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-19K16126, KAKENHI-PROJECT-18H03999, KAKENHI-PROJECT-16H05121
  • [Journal Article] A single K+-binding site in the crystal structure of the gastric proton pump2019

    • Author(s)
      Yamamoto Kenta、Dubey Vikas、Irie Katsumasa、Nakanishi Hanayo、Khandelia Himanshu、Fujiyoshi Yoshinori、Abe Kazuhiro
    • Journal Title

      eLife

      Volume: 8

    • DOI

      10.7554/elife.47701

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17H03653, KAKENHI-PROJECT-17K17795
  • [Journal Article] Enhancement of the thermostability of mouse claudin-3 on complex formation with the carboxyl-terminal region of Clostridium perfringens enterotoxin improves crystal quality2018

    • Author(s)
      Nakamura Shun、Fujiyoshi Yoshinori、Irie Katsumasa
    • Journal Title

      Acta Crystallographica Section F Structural Biology Communications

      Volume: 74 Pages: 150-155

    • DOI

      10.1107/s2053230x18002005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Journal Article] Crystal structures of the gastric proton pump2018

    • Author(s)
      Abe Kazuhiro、Irie Katsumasa、Nakanishi Hanayo、Suzuki Hiroshi、Fujiyoshi Yoshinori
    • Journal Title

      Nature

      Volume: 556 Pages: 214-218

    • DOI

      10.1038/s41586-018-0003-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17K17795, KAKENHI-PROJECT-17H03653
  • [Journal Article] Optimized expression and purification of NavAb provide the structural insight into the voltage dependence2018

    • Author(s)
      Irie Katsumasa、Haga Yukari、Shimomura Takushi、Fujiyoshi Yoshinori
    • Journal Title

      FEBS Letters

      Volume: 592 Pages: 274-283

    • DOI

      10.1002/1873-3468.12955

    • NAID

      120006473551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Journal Article] Molecular determinants of prokaryotic voltage-gated sodium channels for recognition of local anesthetics.2016

    • Author(s)
      T. Shimomura, K. Irie and Y. Fujiyoshi
    • Journal Title

      FEBS Journal

      Volume: 283 Pages: 2881-2895

    • DOI

      10.1111/febs.13776

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 新しい選択性フィルター配列を有する原核生物由来膜電位感受性カルシウムチャネルの同定と機能解析2019

    • Author(s)
      下村拓史、米川佳樹、名倉仁、立山充博、藤吉好則、〇入江克雅
    • Organizer
      "生理学研究所 研究会 「イオンチャネルと生体膜のダイナミズム: 構造生物学の先にあるもの」"
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] Tutorial for physiologists:“Practical Approaches to Protein Structural Information”2019

    • Author(s)
      Katsumasa Irie
    • Organizer
      9th FAOPS congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] 構造生理学的アプローチによるナトリウムチャネルのイオン透過機構の解析2018

    • Author(s)
      入江 克雅
    • Organizer
      蛋白研セミナー:構造情報に基づいた膜イオン輸送タンパク質の 生理機能の解明に向けて
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] Asymmetric interaction of permeating cation and local anesthetic with homo-tetrameric sodium channel2018

    • Author(s)
      入江 克雅
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] 複数の変異体を用いた原核生物由来ナトリウムチャネルの選択性フィルターの構造解析2018

    • Author(s)
      入江克雅、中村駿、藤吉好則
    • Organizer
      第95回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] Unexpected primary sequence of the selectivity filter of endogenous prokaryotic voltage-gated calcium channel2018

    • Author(s)
      Katsumasa Irie, Takushi Shimomura, Toshiki Yonekawa, Hitoshi Nagura, and Yoshinori Fujiyoshi
    • Organizer
      The 49th NIPS International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] ナトリウムイオン選択的透過機構の解明を目指したNavAb変異体の構造解析2017

    • Author(s)
      入江克雅
    • Organizer
      第2 回 イオンチャネル研究会 ~チャネル七夕~
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] 四量体型ナトリウムチャネルにみられる 透過イオンや阻害剤との 非対称な相互作用2017

    • Author(s)
      入江克雅
    • Organizer
      平成29年度生理学研究所研究会 「膜システムの機能的・構造的統合」
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] 「四量体型ナトリウムチャネルの構造機能研究とその応用」2017

    • Author(s)
      入江克雅
    • Organizer
      第2回 医薬系3部局交流シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K17795
  • [Presentation] Characterization of prokaryotic voltage-gated calcium channel2017

    • Author(s)
      Katsumasa Irie, Takushi Shimomura, Toshiki Yonekawa & Yoshinori Fujiyoshi
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-17K17795
  • 1.  FUJIYOSHI Yoshinori (80142298)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  大嶋 篤典 (80456847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  谷 一寿 (20541204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  阿部 一啓 (60596188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  月田 早智子 (00188517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  中村 駿 (80882779)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  鈴木 貴 (40114516)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  後藤 慎平 (50747219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  足立 誠 (30335244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  田村 淳 (00362525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  矢野 智樹 (20546121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  田中 啓雄 (70795905)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  立山 充博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  小林 和人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  神谷 厚範
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  金子 涼輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  落谷 孝広
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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