Irie Katsumasa 入江克雅

Researcher Number	20415087
Other IDs	https://orcid.org/0000-0002-8178-1552
Affiliation (Current)	2021: 和歌山県立医科大学, 薬学部, 准教授 2021: 名古屋大学, 細胞生理学研究センター, 助教
Affiliation (based on the past Project Information) *help	2015 – 2020: 名古屋大学, 細胞生理学研究センター, 助教
Review Section/Research Field	Principal Investigator Biophysics / General physiology / Basic Section 55050:Anesthesiology-related Except Principal Investigator Biophysics / Biological Sciences
Keywords	Principal Investigator 構造解析 / イオンチャネル / X線結晶構造解析 / イオン選択性 / 電気生理学 / 構造生理学 / 構造活性相関 / 局所麻酔薬 / ナトリウムチャネル / 構造機能相関 … More Except Principal Investigator … More

極低温電子顕微鏡を用いた単粒子解析による局所麻酔薬の結合阻害機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  入江克雅
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Nagoya University
Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriersOngoing
- Principal Investigator
  
  月田早智子
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Structural and functional analysis of sodium selective permeation of voltage dependent sodium channelPrincipal Investigator
- Principal Investigator
  
  Irie Katsumasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
  General physiology
- Research Institution
  Nagoya University
Studies in structural physiology of channels
- Principal Investigator
  
  FUJIYOSHI Yoshinori
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biophysics
- Research Institution
  Tokyo Medical and Dental University
  Nagoya University

All 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence.2020
- Author(s)
  Shimomura Takushi、Yonekawa Yoshiki、Nagura Hitoshi、Tateyama Michihiro、Fujiyoshi Yoshinori、Irie Katsumasa
- Journal Title
  
  eLife
  
  Volume: 9 Pages: 1-21
- DOI
  10.7554/elife.52828
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17K08557, KAKENHI-PROJECT-17K17795
[Journal Article] Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression.2019
- Author(s)
  Kamiya Atsunori、Hayama Yohsuke、Kato Shigeki、Shimomura Akihiko、Shimomura Takushi、Irie Katsumasa、Kaneko Ryosuke、Yanagawa Yuchio、Kobayashi Kazuto、Ochiya Takahiro
- Journal Title
  
  第78回日本癌学会学術総会
  
  Volume: 22 Pages: 1289-1305
- DOI
  10.1038/s41593-019-0430-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22474, KAKENHI-PROJECT-18K16408, KAKENHI-PUBLICLY-18H04707, KAKENHI-PUBLICLY-19H04895, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-17H04365, KAKENHI-PROJECT-18K19950, KAKENHI-PROJECT-17K17795, KAKENHI-PROJECT-15KK0331
[Journal Article] Morphologic determinant of tight junctions revealed by claudin-3 structures.2019
- Author(s)
  Nakamura Shun、Irie Katsumasa、Tanaka Hiroo、Nishikawa Kouki、Suzuki Hiroshi、Saitoh Yasunori、Tamura Atsushi、Tsukita Sachiko、Fujiyoshi Yoshinori
- Journal Title
  
  Nat Commun.
  
  Volume: 10 Pages: 255-274
- DOI
  10.1038/s41467-019-08760-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17795, KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-19K16126, KAKENHI-PROJECT-18H03999, KAKENHI-PROJECT-16H05121
[Journal Article] A single K+-binding site in the crystal structure of the gastric proton pump2019
- Author(s)
  Yamamoto Kenta、Dubey Vikas、Irie Katsumasa、Nakanishi Hanayo、Khandelia Himanshu、Fujiyoshi Yoshinori、Abe Kazuhiro
- Journal Title
  
  eLife
  
  Volume: 8
- DOI
  10.7554/elife.47701
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17H03653, KAKENHI-PROJECT-17K17795
[Journal Article] Enhancement of the thermostability of mouse claudin-3 on complex formation with the carboxyl-terminal region of Clostridium perfringens enterotoxin improves crystal quality2018
- Author(s)
  Nakamura Shun、Fujiyoshi Yoshinori、Irie Katsumasa
- Journal Title
  
  Acta Crystallographica Section F Structural Biology Communications
  
  Volume: 74 Pages: 150-155
- DOI
  10.1107/s2053230x18002005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17795
[Journal Article] Crystal structures of the gastric proton pump2018
- Author(s)
  Abe Kazuhiro、Irie Katsumasa、Nakanishi Hanayo、Suzuki Hiroshi、Fujiyoshi Yoshinori
- Journal Title
  
  Nature
  
  Volume: 556 Pages: 214-218
- DOI
  10.1038/s41586-018-0003-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17K17795, KAKENHI-PROJECT-17H03653
[Journal Article] Optimized expression and purification of NavAb provide the structural insight into the voltage dependence2018
- Author(s)
  Irie Katsumasa、Haga Yukari、Shimomura Takushi、Fujiyoshi Yoshinori
- Journal Title
  
  FEBS Letters
  
  Volume: 592 Pages: 274-283
- DOI
  10.1002/1873-3468.12955
- NAID
  120006473551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17795
[Journal Article] Molecular determinants of prokaryotic voltage-gated sodium channels for recognition of local anesthetics.2016
- Author(s)
  T. Shimomura, K. Irie and Y. Fujiyoshi
- Journal Title
  
  FEBS Journal
  
  Volume: 283 Pages: 2881-2895
- DOI
  10.1111/febs.13776
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05775
[Presentation] 新しい選択性フィルター配列を有する原核生物由来膜電位感受性カルシウムチャネルの同定と機能解析2019
- Author(s)
  下村拓史、米川佳樹、名倉仁、立山充博、藤吉好則、〇入江克雅
- Organizer
  "生理学研究所研究会「イオンチャネルと生体膜のダイナミズム：構造生物学の先にあるもの」"
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] Tutorial for physiologists:“Practical Approaches to Protein Structural Information”2019
- Author(s)
  Katsumasa Irie
- Organizer
  9th FAOPS congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] 構造生理学的アプローチによるナトリウムチャネルのイオン透過機構の解析2018
- Author(s)
  入江　克雅
- Organizer
  蛋白研セミナー：構造情報に基づいた膜イオン輸送タンパク質の生理機能の解明に向けて
- Invited
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] Asymmetric interaction of permeating cation and local anesthetic with homo-tetrameric sodium channel2018
- Author(s)
  入江克雅
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] 複数の変異体を用いた原核生物由来ナトリウムチャネルの選択性フィルターの構造解析2018
- Author(s)
  入江克雅、中村駿、藤吉好則
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] Unexpected primary sequence of the selectivity filter of endogenous prokaryotic voltage-gated calcium channel2018
- Author(s)
  Katsumasa Irie, Takushi Shimomura, Toshiki Yonekawa, Hitoshi Nagura, and Yoshinori Fujiyoshi
- Organizer
  The 49th NIPS International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] ナトリウムイオン選択的透過機構の解明を目指したNavAb変異体の構造解析2017
- Author(s)
  入江克雅
- Organizer
  第２回イオンチャネル研究会～チャネル七夕～
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] 四量体型ナトリウムチャネルにみられる透過イオンや阻害剤との非対称な相互作用2017
- Author(s)
  入江克雅
- Organizer
  平成29年度生理学研究所研究会「膜システムの機能的・構造的統合」
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] 「四量体型ナトリウムチャネルの構造機能研究とその応用」2017
- Author(s)
  入江克雅
- Organizer
  第2回　医薬系3部局交流シンポジウム
- Data Source
  KAKENHI-PROJECT-17K17795
[Presentation] Characterization of prokaryotic voltage-gated calcium channel2017
- Author(s)
  Katsumasa Irie, Takushi Shimomura, Toshiki Yonekawa & Yoshinori Fujiyoshi
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K17795

1. FUJIYOSHI Yoshinori (80142298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 大嶋篤典 (80456847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 谷一寿 (20541204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 阿部一啓 (60596188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 月田早智子 (00188517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 中村駿 (80882779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 鈴木貴 (40114516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 後藤慎平 (50747219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 足立誠 (30335244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 田村淳 (00362525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 矢野智樹 (20546121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田中啓雄 (70795905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 立山充博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 小林和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 神谷厚範

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 金子涼輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 落谷孝広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Irie Katsumasa 入江 克雅

Research Projects

Research Products

Co-Researchers

極低温電子顕微鏡を用いた単粒子解析による局所麻酔薬の結合阻害機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriersOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural and functional analysis of sodium selective permeation of voltage dependent sodium channelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies in structural physiology of channels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Morphologic determinant of tight junctions revealed by claudin-3 structures.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A single K+-binding site in the crystal structure of the gastric proton pump2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhancement of the thermostability of mouse claudin-3 on complex formation with the carboxyl-terminal region of Clostridium perfringens enterotoxin improves crystal quality2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structures of the gastric proton pump2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optimized expression and purification of NavAb provide the structural insight into the voltage dependence2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Molecular determinants of prokaryotic voltage-gated sodium channels for recognition of local anesthetics.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 新しい選択性フィルター配列を有する原核生物由来膜電位感受性カルシウムチャネルの同定と機能解析2019

Author(s)

Organizer

Data Source

[Presentation] Tutorial for physiologists:“Practical Approaches to Protein Structural Information”2019

Author(s)

Organizer

Data Source

[Presentation] 構造生理学的アプローチによるナトリウムチャネルのイオン透過機構の解析2018

Author(s)

Organizer

Irie Katsumasa 入江克雅

[Presentation] 四量体型ナトリウムチャネルにみられる透過イオンや阻害剤との非対称な相互作用2017