HARA Toshihide 原利英

Researcher Number	30579769
Affiliation (based on the past Project Information) *help	2013: 東京理科大学, 理工学部情報科学科, 助教 2012 – 2013: 東京理科大学, 理工学部, 助教 2010 – 2011: 東京理科大学, 理工学部・情報科学科, 助教
Review Section/Research Field	Except Principal Investigator General mathematics (including Probability theory/Statistical mathematics) / Statistical science
Keywords	Except Principal Investigator 量子確立論 / 量子確率論 / 量子アルゴリズム / 量子エントロピー / 量子情報 / 数学基礎論 / ケミカルバイオロジー / 生体生命情報学 / 創薬 / バイオインフォマティクス / 統計数学

Development of statistical methodology for analyses of chemical compounds for drug discovery in chemical biology
- Principal Investigator
  
  MATSUURA Masaaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Statistical science
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
Investigation and resolution on basic problems on quantum information theory
- Principal Investigator
  
  OHYA Masanori
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General mathematics (including Probability theory/Statistical mathematics)
- Research Institution
  Tokyo University of Science

All 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] アノテーション情報を考慮したアミノ酸配列アライメント2013
- Author(s)
  原利英, 佐藤圭子, 大矢雅則
- Journal Title
  
  Viva Origino
  
  Volume: 41 Pages: 10-10
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] The code structure of the p53 DNA-binding domain and the prognosis of breast cancer patients2013
- Author(s)
  K.Sato, T.Hara and M.Ohya
- Journal Title
  
  Bioinformatics
  
  Volume: 29(22) Issue: 22 Pages: 2822-2825
- DOI
  10.1093/bioinformatics/btt497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146, KAKENHI-PROJECT-22740071
[Journal Article] Protein Sequence Alignment taking the Structure of Peptide Bond2013
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Journal Title
  
  QP-PQ : Quantum Probability and White Noise Analysis (Quantum Bio-Informatics V)
  
  Volume: 30 Pages: 181-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] カオス結合系を用いた擬似乱数の生成2013
- Author(s)
  淺野耕一朗, 原利英, 大矢雅則
- Journal Title
  
  第52回実函数論・函数解析学合同シンポジウム講演集
  
  Volume: 1 Pages: 17-20
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] A Mathematical Treatment for the Contextual Dependent Bio-Systems2013
- Author(s)
  M. Ohya, T. Hara
- Journal Title
  
  the proceedings of the 32nd Conference on Quantum Probability and Related Topics
  
  Volume: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Protein Sequence Alignment taking the Structure of Peptide Bond2013
- Author(s)
  Hara, T., Sato, K. and Ohya, M.
- Journal Title
  
  QP-PQ: Quantum Probability and White Noise Analysis (Quantum Bio-Informatics V)
  
  Volume: 30 Pages: 181-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-in duced cyto toxicity during glucose deprivation2012
- Author(s)
  Matsuo J, Tsukumo Y, Saito S, Tsukahara S, Sakurai J, Sato S, Kondo H, Ushijima M, Matsuura M, Watanabe T, Tomida A
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 11(5) Issue: 5 Pages: 1082-1091
- DOI
  10.1158/1535-7163.mct-11-0871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300109, KAKENHI-PROJECT-22300342, KAKENHI-PROJECT-22700892, KAKENHI-PROJECT-24240042, KAKENHI-PROJECT-24650626
[Journal Article] Entangled Effects of Two Consecutive Pairs in Residues and Its Use in Alignment2011
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Journal Title
  
  QP-PQ 28, Quantum Bio-Informatics
  
  Volume: IV Pages: 129-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Entangled Effects of Two Consecutive Pairs in Residues and Its Use in Alignment2011
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Journal Title
  
  QP-PQ 28, Quantum Bio-Informatics IV
  
  Volume: 28 Pages: 129-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Entangled Effects of Two Consecutive Pairs in Residues and Its Use in Alignment2011
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Journal Title
  
  Quantum Bio-Informatic
  
  Volume: 4 Pages: 129-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Mathematical description of drug movement into tumor with EPR effect and estimation of its configuration for DDS2010
- Author(s)
  T.Hara, S.Iriyama, K.Makino, H. Terada, M.Ohya
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces
  
  Volume: Vol. 75 Pages: 42-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] MTRAP : Pairwise sequence alignment algorithm by a new measure based on transition probability between two consecutive pairs of residues2010
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Journal Title
  
  BMC Bioinformatics
  
  Volume: 11 Pages: 235-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Mathematical description of drug movement into tumor with EPR effect and estimation of its configuration for DDS2010
- Author(s)
  Hara, T., Iriyama, S., Makino, K., Terada, H. and Ohya, M.
- Journal Title
  
  Colloids Surf B Biointerfaces
  
  Volume: 75 Pages: 42-46
- URL
  http://dx.doi.org/10.1016/j.colsurfb.2009.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300109
[Journal Article] New sequence alignment by a measure due to entangled correlation in two consecutive residues2010
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Journal Title
  
  The 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies Conference Proceedings
  
  Volume: (電子媒体)
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Improvement in Accuracy of Sequence Alignment by the MTRAP algorithm2010
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Journal Title
  
  IEICE Technical Report
  
  Volume: 109,357 Pages: 99-104
- NAID
  110008000419
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Significant Improvement of Sequence Alignment can be Done by Cinsidering Transition Probability between Two Consecutive Paors of Residues2010
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Journal Title
  
  QP-PQ 26, Quantum Bio-Informatics III 26
  
  Pages: 443-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Mathematical description of drug movement into tumor with EPR effect and estimation of its configuration for DDS2010
- Author(s)
  Toshihide Hara, Satoshi Iriyama, Kimiko Makino, Hiroshi Terada, Masanori Ohya
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces 75
  
  Pages: 42-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Mathematical description of drug movement into tumor with EPR effect and estimation of its configuration for DDS2010
- Author(s)
  T.Hara, Iriyama, K.Makino, H.Terada, M.Ohya
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces
  
  Volume: 75 Pages: 42-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] ペア間推移量を用いた配列アライメント法2010
- Author(s)
  原利英, 佐藤圭子, 大矢雅則
- Journal Title
  
  IPSJ SIG Technical Report
  
  Volume: 3(電子媒体)
- NAID
  110007990850
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Improvement in Accuracy of Sequence Alignment by the MTRAP algorithm2009
- Author(s)
  Toshihide Hara, Keiko Sato, Masanori Ohya
- Journal Title
  
  IEICE Technical Report 10
  
  Pages: 99-104
- NAID
  110008000419
- Data Source
  KAKENHI-PROJECT-21540146
[Journal Article] Predictive factors for efficacy of capecitabine in heavily pretreated patients with metastatic breast cancer2009
- Author(s)
  Osako T, Ito Y, Ushijima M, Takahashi S, Tokudome N, Sugihara T, Iwase T, Matsuura M, Hatake K
- Journal Title
  
  Cancer Chemother. Pharmacol
  
  Volume: 63 Pages: 865-871
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/18670777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300109
[Journal Article] Predictive factors for efficacy of capecitabine in heavily pretreated patients with metastatic breast cancer2009
- Author(s)
  Osako T, Ito Y, Ushijima M, Takahashi S, Tokudome N, Sugihara T, Iwase T, Matsuura M, Hatake K.
- Journal Title
  
  Cancer Chemother.Pharmacol. 63(5)
  
  Pages: 865-871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300109
[Journal Article] DDS製剤設計における最適な粒子形状をシミュレーションにより見積もる2009
- Author(s)
  入山聖史, 原利英, 大矢雅則
- Journal Title
  
  第25回日本DDS学会プログラム予稿集 24
  
  Pages: 366-366
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] The Code Structure of Influenza A viruses2013
- Author(s)
  Keiko Sato and Toshihide Hara and Masanori Ohya
- Organizer
  QTAP, QF&QI
- Place of Presentation
  Linnaeus University, Sweden
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] PRNG based on Compound Chaos System2013
- Author(s)
  Toshihide Hara and Masanori Ohya and Koichiro Asano
- Organizer
  2nd Workshop on Information Security
- Place of Presentation
  Tokyo University of Science
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] New Pseudo Random Number Generator by using a Chaos Coupling Map2013
- Author(s)
  Toshihide Hara and Masanori Ohya and Koichiro Asano
- Organizer
  QTAP, QF&QI
- Place of Presentation
  Linnaeus University, Sweden
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] Pseudo Random Number Generator by using a Chaos Coupling Map2013
- Author(s)
  Toshihide Hara and Masanori Ohya and Koichiro Asano
- Organizer
  The 45nd Symposium on Mathematical Physics
- Place of Presentation
  Torun, Poland
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] Some Mathematical Techniques to Study Life Sciences2011
- Author(s)
  T.Hara, M.Ohya
- Organizer
  32nd International Conference on Quantum Probability and Related Topics
- Place of Presentation
  Levico, Italy
- Year and Date
  2011-05-29
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] 生体配列解析を改善する残基ペア間遷移量を用いた革新的手法2011
- Author(s)
  原利英, 佐藤圭子, 大矢雅則
- Organizer
  FIT2011
- Place of Presentation
  函館大学・函館短期大学
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] New seauence alignment algrotithm and its implementation on the computer2011
- Author(s)
  T.Hara, M.Ohya, K.Sato
- Organizer
  ISTC2011
- Place of Presentation
  Tower Hall Funabori
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] A New User Interface of Computer Simulation for Estimating Drug Shape2011
- Author(s)
  T.Sadahiro, T.Hara, S.Iriyama, M.Ohya
- Organizer
  Third Indo-Japanese International Joint Symposium on Overcoming Intractable Infectious Diseases Prevalent in Asian Countries
- Place of Presentation
  Morito Hall, Japan
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] New alignment and software package for sequence analysis2011
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Organizer
  12th International Congress on Amino Acids
- Place of Presentation
  Beijing, China
- Year and Date
  2011-08-01
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] Some mathematical techniques to study life sciences2011
- Author(s)
  Hara, T. Ohya, M
- Organizer
  32^<nd> International Conference on Quantum Probability and Related Topics
- Place of Presentation
  Levico Terme, Italy
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21300109
[Presentation] New Sequence Alignment by Considering Transition Effects of Residue Pair2010
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Organizer
  ICQBIC'10
- Place of Presentation
  Tokyo University of Science
- Year and Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] ペア間推移量を用いた配列アライメント法2010
- Author(s)
  原利英, 佐藤圭子, 大矢雅則
- Organizer
  情報処理学会第22回バイオ情報学研究会
- Place of Presentation
  産総研臨海副都心センター別館, 東京
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] Graphical User Interface of Numerical Analysis for DDS2010
- Author(s)
  T.Sadahiro, T.Hara, M.Ohya
- Organizer
  ICQBIC'10
- Place of Presentation
  Tokyo University of Science
- Year and Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] Improvement in Accuracy of Sequence Alignment by the MTRAP algorithm2010
- Author(s)
  Toshihide Hara, Keiko Sato, Masanori Ohya
- Organizer
  IEICE Information Theory
- Place of Presentation
  Campus Center, University of Hawaii at Manoa, Hawaii, USA
- Year and Date
  2010-01-07
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] New sequence alignment by a measure due to entangled correlation in two consecutive residues2010
- Author(s)
  T.Hara, K.Sato, M.Ohya
- Organizer
  ISABEL
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] Performance Evalation of Science Alignment by Means of MTRAP Algorithm2010
- Author(s)
  K.Ito, T.Hara, M.Ohya
- Organizer
  ICQBIC'10
- Place of Presentation
  Tokyo University of Science
- Year and Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-21540146
[Presentation] DDS製剤設計における最適な粒子形状をシミュレーションにより見積もる2009
- Author(s)
  入山聖史, 原利英, 大矢雅則
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京ドームホテル, 東京
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-21540146

1. MATSUURA Masaaki (40173794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. HOSHIKAWA Yutaka (80280626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. MIYATA Satoshi (60360343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. USHIJIMA Masaru (60328565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. ISOMURA Minoru (40272497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMORI Takao (60200854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. DAN Shingo (70332202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OHYA Masanori (90112896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 35 results
9. IRIYAMA Satoshi (10385528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. MATSUOKA Takashi (90328568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 浅野真誠 (80408707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. 佐藤圭子 (30366439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results

HARA Toshihide 原 利英

Research Projects

Research Products

Co-Researchers

Development of statistical methodology for analyses of chemical compounds for drug discovery in chemical biology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation and resolution on basic problems on quantum information theory

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] アノテーション情報を考慮したアミノ酸配列アライメント2013

Author(s)

Journal Title

Data Source

[Journal Article] The code structure of the p53 DNA-binding domain and the prognosis of breast cancer patients2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein Sequence Alignment taking the Structure of Peptide Bond2013

Author(s)

Journal Title

Data Source

[Journal Article] カオス結合系を用いた擬似乱数の生成2013

Author(s)

Journal Title

Data Source

[Journal Article] A Mathematical Treatment for the Contextual Dependent Bio-Systems2013

Author(s)

Journal Title

Data Source

[Journal Article] Protein Sequence Alignment taking the Structure of Peptide Bond2013

Author(s)

Journal Title

Data Source

[Journal Article] Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-in duced cyto toxicity during glucose deprivation2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Entangled Effects of Two Consecutive Pairs in Residues and Its Use in Alignment2011

Author(s)

Journal Title

Data Source

[Journal Article] Entangled Effects of Two Consecutive Pairs in Residues and Its Use in Alignment2011

Author(s)

Journal Title

Data Source

[Journal Article] Entangled Effects of Two Consecutive Pairs in Residues and Its Use in Alignment2011

Author(s)

Journal Title

Data Source

[Journal Article] Mathematical description of drug movement into tumor with EPR effect and estimation of its configuration for DDS2010

Author(s)

Journal Title

Data Source

[Journal Article] MTRAP : Pairwise sequence alignment algorithm by a new measure based on transition probability between two consecutive pairs of residues2010

Author(s)

Journal Title

Data Source

[Journal Article] Mathematical description of drug movement into tumor with EPR effect and estimation of its configuration for DDS2010

Author(s)

Journal Title

URL

Data Source

[Journal Article] New sequence alignment by a measure due to entangled correlation in two consecutive residues2010

Author(s)

Journal Title

Data Source

[Journal Article] Improvement in Accuracy of Sequence Alignment by the MTRAP algorithm2010

Author(s)

Journal Title

NAID

Data Source

HARA Toshihide 原利英