Uchida Yoichiro 内田洋一朗

… Alternative Names

UCHIDA Yoichiro 内田洋一朗

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Researcher Number	30597745
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 講師 2025: 公益財団法人田附興風会, 医学研究所北野病院腫瘍研究部, 研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 京都大学, 医学研究科, 講師 2019 – 2022: 京都大学, 医学研究科, 助教 2013 – 2018: 公益財団法人田附興風会, 医学研究所第1研究部, 主任研究員 2015: 公益財団法人田附興風会, 医学研究所第1研究部, 主任研究員 2011 – 2013: 京都大学, 医学(系)研究科(研究院), 非常勤講師
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Digestive surgery Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / General surgery / Digestive surgery
Keywords	Principal Investigator 肝虚血再灌流障害 / 肝移植 / 絶食 / TLR-4 / Galectin-9 / ケトン体 / 脂肪肝移植 / ERAS / 腸内細菌 / 食事制限 … More / プロピオン酸 / 短鎖脂肪酸 / 腸内細菌叢 / イヌリン / 5-アミノレブリン酸 / 肝臓外科 / Tim-3 / TIM-3 / クッパー細胞 / 国際情報交流 / ガレクチン / アメリカ / 国際情報交換 / 自然免疫 / マクロファージ / T細胞 / TIM / 肝臓 / 虚血再灌流障害 … More Except Principal Investigator 肝虚血再灌流障害 / 肝臓 / メタボローム解析 / 肝移植 / 肝臓外科 / 絶食 / 虚血再灌流障害 / TLR-4 / 虚血再還流障害 / normothermic / liver transplantation / gene therapy / heme oxygenase / machine perfusion / 機械灌流 / レシピエント / 自然免役細胞 / ERAS / 5-アミノレブリン酸 / 体内時計 / 概日リズム / 肝虚血再還流障害 / βヒドロキシ酪酸 / アセチル化ヒストン / FOXO1 / 食事制限 / HMGB－１ / D1分画 / HMGB-1 / トロンボモジュリン / Galectin-9 / TIM / マクロファージ / TIM-3 / T細胞 / Tim-3 / galectin-9 Less

マウス脂肪肝移植を用いた代謝免疫学的アプローチによる肝虚血再灌流障害の機序解明Principal Investigator
- Principal Investigator
  
  内田洋一朗
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto University
Precise liver gene theraphy based on individual HO-1 morphism with normothermic machine perfusion
- Principal Investigator
  
  影山詔一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto University
非感染性炎症における新たな自然免疫細胞制御機構の探求
- Principal Investigator
  
  中村公治郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto University
The involvement of circadian rhythm in liver ischemia-reperfusion injury
- Principal Investigator
  
  Terajima Hiroaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  The Tazuke Kofukai
The Efficacy of dietary therapy and analysis of gut microbiota in liver surgeryPrincipal Investigator
- Principal Investigator
  
  Uchida Yoichiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto University
The elucidation of mechanism of liver ischemia and reperfusion injury by diet restriction
- Principal Investigator
  
  Terajima Hiroaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  The Tazuke Kofukai
The elucidation for the suppressive effect of thrombomodulin in liver ischemia and reperfusion injury
- Principal Investigator
  
  TERAJIMA Hiroaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The Tazuke Kofukai
The elucidation for the role of Galectin-9 in liver ischemia and reperfusion injuryPrincipal Investigator
- Principal Investigator
  
  UCHIDA Yoichiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The Tazuke Kofukai
The elucidation of novel T cell function in innate immunity-dominated liver tissue damage.
- Principal Investigator
  
  TERAJIMA Hiroaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  The Tazuke Kofukai
The Novel Role of T cell in Liver Ischemia and Reperfusion InjuryPrincipal Investigator
- Principal Investigator
  
  UCHIDA Yoichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University

All 2023 2020 2019 2018 2017 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Up-regulation of FOXO1 and reduced inflammation by β-hydroxybutyric acid are essential diet restriction benefits against liver injury2019
- Author(s)
  Miyauchi Tomoyuki、Uchida Yoichiro、Kadono Kentaro、Hirao Hirofumi、Kawasoe Junya、Watanabe Takeshi、Ueda Shugo、Okajima Hideaki、Terajima Hiroaki、Uemoto Shinji
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 27 Pages: 13533-13542
- DOI
  10.1073/pnas.1820282116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08609
[Journal Article] Thrombomodulin attenuates inflammatory damage due to liver ischemia and reperfusion injury in mice in Toll-like Receptor 4-dependent manner2017
- Author(s)
  K. Kadono, Y. Uchida, H. Hirao, T. Miyauchi, T. Watanabe, T. Iida, S. Ueda, A. Kanazawa, A. Mori, H. Okajima, H. Terajima, S. Uemoto
- Journal Title
  
  American J. of Transplantation
  
  Volume: 17 Issue: 1 Pages: 69-80
- DOI
  10.1111/ajt.13991
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24111009, KAKENHI-PROJECT-15K10041
[Journal Article] The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.2015
- Author(s)
  Hirofumi Hirao, Yoichiro Uchida, Kentaro Kadono, Hirokazu Tanaka, Toshiro Niki, Akira Yamauchi, Koichiro Hata, Takeshi Watanabe, Hiroaki Terajima, Shinji Uemoto
- Journal Title
  
  Liver Transplantation
  
  Volume: 21 Issue: 7 Pages: 969-981
- DOI
  10.1002/lt.24159
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10177, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-25670590, KAKENHI-PLANNED-24111009
[Journal Article] Interleukin-22 : Implications for Liver Ischemia-Reperfusion Injury2012
- Author(s)
  Chestovich PJ, Uchida Y, Chang W, Ajalat M, Lassman C, Sabat R, Busuttil RW, Kupiec-Weglinski JW.
- Journal Title
  
  Transplantation
  
  Volume: 93 Pages: 485-492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791527
[Journal Article] Progressive graft fibrosis and donor-specific HLA antibodies in pediatric late liver allografts2012
- Author(s)
  Miyagawa-Hayashino A, Yoshizawa A, Uchida Y, Egawa H, Yurugi K, Masuda S, Minamiguchi S, Maekawa T, Uemoto S, Haga H.
- Journal Title
  
  Liver Transpl
  
  Volume: 18 Pages: 1333-1342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791527
[Journal Article] Native macrophages genetically modified to express heme oxygenase 1 protect rat liver transplants from ischemia/reperfusion injury2011
- Author(s)
  Shen XD, Ke B, Uchida Y, Ji H, Gao F, Zhai Y, Busuttil RW, Kupiec-Weglinski JW.
- Journal Title
  
  Liver Transpl
  
  Volume: 17 Pages: 201-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791527
[Journal Article] Type I Interferon Pathway Mediates Renal Ischemia/Reperfusion Injury2011
- Author(s)
  Freitas MC, Uchida Y, Lassman C, Danovitch GM, Busuttil RW, Kupiec-Weglinski JW.
- Journal Title
  
  Transplantation
  
  Volume: 92 Pages: 131-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791527
[Journal Article] Association of anti-HLA and anti-Angiotensin II Type 1 Receptor Antibodies with Liver Allograft Fibrosis after Immunosuppression Withdrawal
- Author(s)
  Ohe H, Uchida Y, Yoshizawa A, Hirao H, Taniguchi M, Maruya E, Yurugi K, Hishida R, Maekawa T, Uemoto S, Terasaki PI.
- Journal Title
  
  Transplantation
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791527
[Journal Article] Whey-hydrolyzed peptide-enriched immunomodulating diet prevents progression of liver cirrhosis in rats
- Author(s)
  Jobara K, Kaido T, Hori T, Iwaisako K, Endo K, Uchida Y, Uemoto S.
- Journal Title
  
  Nutrition
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791527
[Presentation] 肝移植周術期における好中球細胞死（ネトーシス）の意義ー基礎研究から臨床応用へ2023
- Author(s)
  平尾浩史、中村公治郎、内田洋一朗、波多野悦朗
- Organizer
  第59回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-22K08749
[Presentation] Current situation in postoperative adjuvant chemotherapy and perioperative nutritional management for the treatment of pancreatic cancer2020
- Author(s)
  Yoichiro Uchida,Ryo Kamimura,Tomohiro Okamoto,Takayuki Kawai,Kohta Iguchi,Hiroaki Terajima
- Organizer
  14th World Congress of the International Hepato-Pacreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08609
[Presentation] 肝臓外科手術における短期食事制限の有用性－基礎的見地からの検討－2020
- Author(s)
  内田洋一朗,宮内智之,川添准矢,嵯峨謙一,寺嶋宏明,上本伸二
- Organizer
  第57回日本外科代謝栄養学会
- Data Source
  KAKENHI-PROJECT-18K08609
[Presentation] Our trial to develop academic surgeon2020
- Author(s)
  Yoichiro Uchida,Hiroaki Terajima,Junya Kawasoe,Kenichi Saga,Tomoyuki Miyauchi,Shugo Ueda,Shinji Uemoto
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08609
[Presentation] 肝臓外科術後合併症の軽減に対する栄養療法の可能性2019
- Author(s)
  宮内智之、内田洋一朗、海道利実、上本伸二
- Organizer
  第34回日本静脈経腸栄養学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10177
[Presentation] 肝臓外科術後合併症の軽減に対する栄養療法の可能性2019
- Author(s)
  宮内智之、内田洋一朗、海道利実、上本伸二
- Organizer
  第34回日本静脈経腸栄養学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08609
[Presentation] Thrombomodulin suppresses inflammatory damage due to liver ischemia and reperfusion injury in mice in TLR-4 dependent manner2018
- Author(s)
  Kentaro Kadono,Yoichiro Uchida, Akimori Miki, Ryo Ohno, Tomoyuki Miyauchi, Tomohiro Okamoto, Ryo Kamimura, Masashi Horiguchi, Meiki Fukuda, Takeshi Watanabe, Shugo Ueda, Hiroaki Terajima
- Organizer
  The 53rd Congress of the European Society for Surgical Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10041
[Presentation] トロンボモジュリンによる肝虚血再灌流障害の改善とその作用機序の解明2017
- Author(s)
  門野賢太郎、内田洋一朗、平尾浩史、宮内智之、堀口雅史、上田修吾、金澤旭宣、寺嶋宏明、岡島英明、上本伸二
- Organizer
  第117回日本外科学会総会
- Data Source
  KAKENHI-PROJECT-15K10041
[Presentation] 肝内胆管癌に対する集学的治療戦略2015
- Author(s)
  内田洋一朗、寺嶋宏明、飯田拓、高忠之
- Organizer
  第51回日本肝臓学会
- Place of Presentation
  鶴屋東館（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K10177
[Presentation] 当院における高度局所進行膵癌に対する治療戦略2015
- Author(s)
  内田洋一朗、大野龍、後藤徹、岡本拓也、上田修吾、森章、金澤旭宣、寺嶋宏明
- Organizer
  第77回日本臨床外科学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-15K10177
[Presentation] 当科における胆道癌に対する肝膵同時切除の治療成績の検討2015
- Author(s)
  内田洋一朗、寺嶋宏明、松原弘侑、後藤徹、岩村宣亜、飯田拓
- Organizer
  第27回肝胆膵外科学会
- Place of Presentation
  ホテルグランパシフィック LE DAIBA （東京都港区）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K10041
[Presentation] 肝虚血再灌流障害と自然免疫の新しいメカニズムの解明―T cell Macrophage Cross-Talk―2015
- Author(s)
  内田洋一朗、平尾　浩史、門野　賢太郎、田中　宏和、吉冨　摩美、飯田　拓、上田　修吾、金澤　旭宣、上本　伸二、寺嶋　宏明
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25670590
[Presentation] 肝虚血再灌流障害におけるIL-22の保護効果2013
- Author(s)
  内田洋一朗、加茂直子、平尾浩史、田中宏和、寺嶋宏明、Ronald W. Busuttil、Jerzy W. Kupiec-Weglinski、上本伸二
- Organizer
  第113回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23791527
[Presentation] 肝虚血再灌流障害におけるTIM-3(T-Cell Immunoglobulin Mucin-3)とGalectin-9およびTLR-4とのCross-Talk2012
- Author(s)
  内田洋一朗、加茂直子、Ronald W. Busuttil、Jerzy W. Kupiec-Weglinski、上本伸二
- Organizer
  第112回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23791527
[Presentation] 肝虚血再灌流障害におけるT Cell Ig Mucin-3 (TIM-3)の役割2011
- Author(s)
  内田洋一朗、加茂直子、Ronald W. Busuttil、Jerzy W. Kupiec-、上本伸二
- Organizer
  第111回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23791527

1. WATANABE Takeshi (40028684)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. TERAJIMA Hiroaki (40314215)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
3. 中村公治郎 (10848203)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. 影山詔一 (60707545)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 岡島英明 (20308604)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. 波多野悦朗 (80359801)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. KADONO Kentaro (10816094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 宮内智之 (10852303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 平尾浩史 (80978817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. YAMAUCHI Akira (00291427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 上本伸二 (40252449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 瀬尾智 (70646546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 川添准矢 (60911295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 秦浩一郎 (90523118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 渡辺武

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Uchida Yoichiro 内田 洋一朗

UCHIDA Yoichiro 内田 洋一朗

Research Projects

Research Products

Co-Researchers

マウス脂肪肝移植を用いた代謝免疫学的アプローチによる肝虚血再灌流障害の機序解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Precise liver gene theraphy based on individual HO-1 morphism with normothermic machine perfusion

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非感染性炎症における新たな自然免疫細胞制御機構の探求

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The involvement of circadian rhythm in liver ischemia-reperfusion injury

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Efficacy of dietary therapy and analysis of gut microbiota in liver surgeryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of mechanism of liver ischemia and reperfusion injury by diet restriction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation for the suppressive effect of thrombomodulin in liver ischemia and reperfusion injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The elucidation for the role of Galectin-9 in liver ischemia and reperfusion injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The elucidation of novel T cell function in innate immunity-dominated liver tissue damage.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Novel Role of T cell in Liver Ischemia and Reperfusion InjuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Up-regulation of FOXO1 and reduced inflammation by β-hydroxybutyric acid are essential diet restriction benefits against liver injury2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thrombomodulin attenuates inflammatory damage due to liver ischemia and reperfusion injury in mice in Toll-like Receptor 4-dependent manner2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.2015

Author(s)

Journal Title

DOI

Data Source

Uchida Yoichiro 内田洋一朗

UCHIDA Yoichiro 内田洋一朗

[Presentation] 肝臓外科手術における短期食事制限の有用性－基礎的見地からの検討－2020