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XIE LIN  謝 琳

… Alternative Names

XIE Lin  謝 琳

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Researcher Number 30623558
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6472-322X
Affiliation (Current) 2023: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所 先進核医学基盤研究部, 主任研究員
Affiliation (based on the past Project Information) *help 2021 – 2022: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所 先進核医学基盤研究部, 主任研究員
2019 – 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 先進核医学基盤研究部, 主任研究員(定常)
2018: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 標識薬剤開発部, 研究員(定常)
2016 – 2017: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 標識薬剤開発部, 研究員(任常)
2016: 国立研究開発法人量子科学技術研究開発機構, 分子イメージング研究センター, 研究員 … More
2016: 国立研究開発法人量子科学技術研究開発機構, 標識薬剤開発部, 研究員
2015: 国立研究開発法人放射線医学総合研究所, 分子イメージング研究センター, 研究員
2014: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 研究員
2012 – 2013: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 博士研究員 Less
Review Section/Research Field
Principal Investigator
Applied pharmacology / Radiation science / Basic Section 52040:Radiological sciences-related
Except Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related
Keywords
Principal Investigator
肝疾患 / TSPO / PET診断 / 脂肪肝 / PET / [18]FEDAC / 画像診断法 / [18F]FEDAC / 生体分子 / 肝癌 … More / 先制医療 / PET診断法 / 代謝型グルタミン酸受容体1型 / Radio-theranostics / PET診断薬 / α線治療薬 / mGluR1 / TRT治療 … More
Except Principal Investigator
PET / 核医学 / 分子イメージング / PETプローブ / 画像化 / オートラジオグラフィ / mGluR1 / 腫瘍 / 放射性プローブ / 摂食 / 肥満 / イミダゾリン受容体 / グレリン受容体 / 分子イメージング / イミダゾリンI2受容体 / 放射線 / 肥満症 / モノアシルグリセロールリパーゼ / MAGL / ポジトロン エミッション トモグラフィ / ポジトロン エミッション トモグラフィー / 代謝型グルタミン酸受容体 / mGluR2 / 代謝型グルタミン酸受容体サブタイプ2 / [11C]DMTN / 18F / 光線力学的療法 / 光感受性物質 / フッ素-18 / 炭素-11 / 11C / BODIPY / 膜貫通AMPA受容体調節性タンパク質-γ8 / AMPA受容体 / オートラジオグラフィー / 膜貫通AMPA受容体調節性タンパク質 / stapled peptide / radiotheranostics / intracellular protein / cancer / 64Cu / radionuclide therapy / intracellular delivery / PET imaging / 銅-64 / 抗体 / 位置特異的修飾 / 糖鎖修飾抗体 / 位置特異的修飾方法 / 放射性治療核種 Less
  • Research Projects

    (11 results)
  • Research Products

    (88 results)
  • Co-Researchers

    (11 People)
  •  Stapled peptide-based radiotheranostics for intracellular protein-protein interactions targeted cancer imaging and therapy

    • Principal Investigator
      胡 寛
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  mGluR1を標的とするα線Radio-theranosticsシステムの確立Principal Investigator

    • Principal Investigator
      謝 琳
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  キレーター含有糖ユニットで修飾した抗体の標識反応と評価

    • Principal Investigator
      破入 正行
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Development of PET probes for gama 8-dependent transmembrane AMPA receptor regulatory protein

    • Principal Investigator
      張 明栄
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  新規PET用トレーサーを用いた光線力学的療法の安全性及び治療効果評価手法の構築

    • Principal Investigator
      河村 和紀
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Visualization of monoacylglycerol lipase in ischemia rat brain using [11C]SAR127303 and development of new PET probes.

    • Principal Investigator
      HATORI Akiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Establishing TSPO-PETimaging for the diagnosis of liver diseasesPrincipal Investigator

    • Principal Investigator
      XIE Lin
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of novel PET probes for imaging of metabotropic glutamate receptor subtype 2

    • Principal Investigator
      Zhang Ming-Rong
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of imaging agents for feeding function as a diagnostic tool and evaluation of drug therapy for obesity

    • Principal Investigator
      KAWAMURA KAZUNORI
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of radioprobes by targeted metabotropic glutamate receptor 1 in tumor

    • Principal Investigator
      Ming Rong Zhang
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of TSPO-PET imaging for noninvasive diagnosis of liver diseasesPrincipal Investigator

    • Principal Investigator
      XIE Lin
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      National Institute of Radiological Sciences

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Whole-body PET tracking of a d-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors2022

    • Author(s)
      Hu Kuan, Wu Wenyu, Xie Lin, Geng Hao, Zhang Yiding, Hanyu Masayuki, Zhang Lulu, Liu Yinghuan, Nagatsu Kotaro, Suzuki Hisashi, Guo Jialin, Wu Yundong, Li Zigang, Wang Feng, Zhang Ming-Rong
    • Journal Title

      Acta Pharmaceutica Sinica B

      Volume: 12 Pages: 1363-1376

    • DOI

      10.1016/j.apsb.2021.09.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714
  • [Journal Article] Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold2021

    • Author(s)
      Rong Jian, Mori Wakana, Xia Xiaotian, Zhang Ming-Rong, Liang Steven
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 64 Pages: 14283-14298

    • DOI

      10.1021/acs.jmedchem.1c00747

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21K07659
  • [Journal Article] Development of a Stable Peptide-Based PET Tracer for Detecting CD133-Expressing Cancer Cells2021

    • Author(s)
      Hu Kuan、Ma Xiaohui、Xie Lin、Zhang Yiding、Hanyu Masayuki、Obata Honoka、Zhang Lulu、Nagatsu Kotaro、Suzuki Hisashi、Shi Rui、Wang Weizhi、Zhang Ming-Rong
    • Journal Title

      ACS Omega

      Volume: 7 Pages: 334-341

    • DOI

      10.1021/acsomega.1c04711

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714
  • [Journal Article] Off-tumor IDO1 target engagements determine the cancer-immune set point and predict the immunotherapeutic efficacy2021

    • Author(s)
      Xie Lin, Hu Kuan, Duo Yanhong, Shimokawa Takashi, Kumata Katsushi, Zhang Yiding, Jiang Cuiping, Zhang Lulu, Nengaki Nobuki, Wakizaka Hidekatsu, Cao Yihai, Zhang Ming-Rong
    • Journal Title

      Journal for ImmunoTherapy of Cancer

      Volume: 9

    • DOI

      10.1136/jitc-2021-002616

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21K07659
  • [Journal Article] 211At-Labeled Polymer Nanoparticles for Targeted Radionuclide Therapy of Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR)-Overexpressed Cancer2021

    • Author(s)
      Shi Xiumin、Li Qing、Zhang Lulu、Hanyu Masayuki、Xie Lin、Hu Kuan、Nagatsu Kotaro、Zhang Chuan、Wu Zhengcan、Wang Feng、Zhang Ming-Rong、Yang Kai、Zhu Ran
    • Journal Title

      Bioconjugate Chemistry

      Volume: 32 Pages: 1763-1772

    • DOI

      10.1021/acs.bioconjchem.1c00263

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659
  • [Journal Article] PET Imaging of VEGFR with a Novel 64Cu-Labeled Peptide2020

    • Author(s)
      Hu Kuan、Shang Jingjie、Xie Lin、Hanyu Masayuki、Zhang Yiding、Yang Zhimin、Xu Hao、Wang Lu、Zhang Ming-Rong
    • Journal Title

      ACS Omega

      Volume: 5 Pages: 8508-8514

    • DOI

      10.1021/acsomega.9b03953

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156
  • [Journal Article] Synthesis and evaluation of 6-(11C-methyl(4-(pyridin-2-yl)thiazol-2-yl)amino)benzo[d]thiazol-2(3H)-one for imaging γ-8 dependent transmembrane AMPA receptor regulatory protein by PET2020

    • Author(s)
      Yu Qingzhen、Kumata Katsushi、Li Hua、Zhang Yiding、Chen Zhen、Zhang Xiaofei、Shao Tuo、Hatori Akiko、Yamasaki Tomoteru、Xie Lin、Hu Kuan、Wang Gangqiang、Josephson Lee、Sun Shaofa、Zhang Ming-Rong、Liang Steven H.
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 30 Pages: 126879-126879

    • DOI

      10.1016/j.bmcl.2019.126879

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2)2020

    • Author(s)
      Yamasaki Tomoteru、Zhang Xiaofei、Kumata Katsushi、Zhang Yiding、Deng Xiaoyun、Fujinaga Masayuki、Chen Zhen、Mori Wakana、Hu Kuan、Wakizaka Hidekatsu、Hatori Akiko、Xie Lin、Ogawa Masanao、Nengaki Nobuki、Van Richard、Shao Yihan、Sheffler Douglas J.、Cosford Nicholas D. P.、Liang Steven H.、Zhang Ming-Rong
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 63 Pages: 11469-11483

    • DOI

      10.1021/acs.jmedchem.9b01991

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators2020

    • Author(s)
      Sun Ji-yun、Kumata Katsushi、Chen Zhen、Zhang Yi-ding、Chen Jia-hui、Hatori Akiko、Fu Hua-long、Rong Jian、Deng Xiao-yun、Yamasaki Tomoteru、Xie Lin、Hu Kuan、Fujinaga Masayuki、Yu Qing-zhen、Shao Tuo、Collier Thomas Lee、Josephson Lee、Shao Yi-han、Du Yun-fei、Wang Lu、Xu Hao、Zhang Ming-rong、Liang Steven H
    • Journal Title

      Acta Pharmacologica Sinica

      Volume: 42 Pages: 491-498

    • DOI

      10.1038/s41401-020-0456-9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Synthesis and preliminary studies of 11C-labeled tetrahydro-1,7-naphthyridine-2-carboxamides for PET imaging of metabotropic glutamate receptor 22020

    • Author(s)
      Zhang Xiaofei、Zhang Yiding、Chen Zhen、Shao Tuo、Van Richard、Kumata Katsushi、Deng Xiaoyun、Fu Hualong、Yamasaki Tomoteru、Rong Jian、Hu Kuan、Hatori Akiko、Xie Lin、Yu Qingzhen、Ye Weijian、Xu Hao、Sheffler Douglas J.、Cosford Nicholas D. P.、Shao Yihan、Tang Pingping、Wang Lu、Zhang Ming-Rong、Liang Steven H.
    • Journal Title

      Theranostics

      Volume: 10 Pages: 11178-11196

    • DOI

      10.7150/thno.42587

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Synthesis and evaluation of 4-(2-fluoro-4-[11C]methoxyphenyl)-5-((2-methylpyridin-4-yl)methoxy)picolinamide for PET imaging of the metabotropic glutamate receptor 2 in the rat brain2019

    • Author(s)
      Kumata Katsushi、Hatori Akiko、Yamasaki Tomoteru、Zhang Yiding、Mori Wakana、Fujinaga Masayuki、Xie Lin、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 27 Pages: 483-491

    • DOI

      10.1016/j.bmc.2018.12.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation2019

    • Author(s)
      Kuan Hu、Masayuki Hanyu、Xie Lin、Zhang Yiding、Kotaro Nagatsu、Hisashi Suzuki、Zhang Ming-Rong
    • Journal Title

      Chemical Communications

      Volume: 55 Pages: 4162-4165

    • DOI

      10.1039/c9cc00445a

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H06217, KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-17K16495
  • [Journal Article] 131I-IITM and 211At-AITM: Two Novel Small-Molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 12019

    • Author(s)
      Xie Lin、Hanyu Masayuki、Fujinaga Masayuki、Zhang Yiding、Hu Kuan、Minegishi Katsuyuki、Jiang Cuiping、Kurosawa Fuki、Morokoshi Yukie、Li Huizi Keiko、Hasegawa Sumitaka、Nagatsu Kotaro、Zhang Ming-Rong
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 61 Pages: 242-248

    • DOI

      10.2967/jnumed.119.230946

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
  • [Journal Article] Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[11C]carboxylate2019

    • Author(s)
      Mori Wakana、Hatori Akiko、Zhang Yiding、Kurihara Yusuke、Yamasaki Tomoteru、Xie Lin、Kumata Katsushi、Hu Kuan、Fujinaga Masayuki、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 27 Pages: 3568-3573

    • DOI

      10.1016/j.bmc.2019.06.037

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K10461, KAKENHI-PROJECT-17K16495
  • [Journal Article] Design, synthesis, and evaluation of reversible and irreversible monoacylglycerol lipase positron emission tomography (PET) tracers using a “Tail Switching” strategy on a piperazinyl azetidine skeleton2019

    • Author(s)
      Chen Zhen、Mori Wakana、Deng Xiaoyun、Cheng Ran、Ogasawara Daisuke、Zhang Genwei、Schafroth Michael A.、Dahl Kenneth、Fu Hualong、Hatori Akiko、Shao Tuo、Zhang Yiding、Yamasaki Tomoteru、Zhang Xiaofei、Rong Jian、Yu Qingzhen、Hu Kuan、Fujinaga Masayuki、Xie Lin、Kumata Katsushi、Gou Yuancheng、Chen Jingjin、Gu Shuyin
    • Journal Title

      Jounal of Medicinal Chemistry

      Volume: 62 Pages: 3336-3353

    • DOI

      10.1021/acs.jmedchem.8b01778

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10461, KAKENHI-PROJECT-18H06217, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
  • [Journal Article] Correction: Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation2019

    • Author(s)
      Hu Kuan、Hanyu Masayuki、Xie Lin、Zhang Yiding、Nagatsu Kotaro、Suzuki Hisashi、Zhang Ming-Rong
    • Journal Title

      Chemical Communications

      Volume: 55 Pages: 4273-4273

    • DOI

      10.1039/c9cc90113b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] [18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18 kDa)2018

    • Author(s)
      Kumata Katsushi、Zhang Yiding、Fujinaga Masayuki、Ohkubo Takayuki、Mori Wakana、Yamasaki Tomoteru、Hanyu Masayuki、Xie Lin、Hatori Akiko、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 26 Pages: 4817-4822

    • DOI

      10.1016/j.bmc.2018.08.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-17H04267
  • [Journal Article] Change in the Binding of [11C]BU99008 to Imidazoline I2 Receptor Using Brain PET in Zucker Rats2018

    • Author(s)
      Kawamura Kazunori、Yamasaki Tomoteru、Zhang Yiding、Wakizaka Hidekatsu、Hatori Akiko、Xie Lin、Fujinaga Masayuki、Zhang Ming-Rong
    • Journal Title

      Molecular Imaging and Biology

      Volume: 印刷中

    • DOI

      10.1007/s11307-018-1206-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Journal Article] 18F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with18F-FDG2018

    • Author(s)
      Chung Seock-Jin、Yoon Hai-Jeon、Youn Hyewon、Kim Mi Jeong、Lee Yun-Sang、Jeong Jae Min、Chung June-Key、Kang Keon Wook、Xie Lin、Zhang Ming-Rong、Cheon Gi Jeong
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 59 Pages: 839-845

    • DOI

      10.2967/jnumed.117.200667

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Journal Article] In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies2018

    • Author(s)
      Ran Cheng, Wakana Mori, Longle Ma, Mireille Alhouayek, Akiko Hatori, Yiding Zhang, Daisuke Ogasawara, Gengyang Yuan, Zhen Chen, Xiaofei Zhang, Hang Shi, Tomoteru Yamasaki, Lin Xie, Katsushi Kumata, Masayuki Fujinaga, Yuji Nagai, Takafumi Minamimoto, Mona Svensson, Lu Wang, Yunfei Du, Mary Jo Ondrechen, Neil Vasdev
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 61 Pages: 2278-2291

    • DOI

      10.1021/acs.jmedchem.7b01400

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10461, KAKENHI-PLANNED-15H05917
  • [Journal Article] Pharmacokinetic Evaluation of [11C]CEP-32496 in Nude Mice Bearing BRAFV600E Mutation-Induced Melanomas2018

    • Author(s)
      Jiang Cuiping、Xie Lin、Zhang Yiding、Fujinaga Masayuki、Mori Wakana、Kurihara Yusuke、Yamasaki Tomoteru、Wang Feng、Zhang Ming-Rong
    • Journal Title

      Molecular Imaging

      Volume: 17 Pages: 59-52

    • DOI

      10.1177/1536012118795952

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Journal Article] Development of 2-(2-(3-(4-([18F]Fluoromethoxy-d2)phenyl)-7-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-4-isopropoxyisoindoline-1,3-dione for Positron-Emission-Tomography Imaging of Phosphodiesterase 10A in the Brain2018

    • Author(s)
      Mori Wakana、Yamasaki Tomoteru、Fujinaga Masayuki、Ogawa Masanao、Zhang Yiding、Hatori Akiko、Xie Lin、Kumata Katsushi、Wakizaka Hidekatsu、Kurihara Yusuke、Ohkubo Takayuki、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 62 Pages: 688-698

    • DOI

      10.1021/acs.jmedchem.8b01366

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain2018

    • Author(s)
      Fujinaga Masayuki、Kumata Katsushi、Zhang Yiding、Hatori Akiko、Yamasaki Tomoteru、Mori Wakana、Ohkubo Takayuki、Xie Lin、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 16 Pages: 8325-8335

    • DOI

      10.1039/c8ob01700j

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-17H04267
  • [Journal Article] Evaluation of the novel TSPO radiotracer 2-(7-butyl-2-(4-(2-([18F]fluoroethoxy)phenyl)-5-methylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide in a preclinical model of neuroinflammation2018

    • Author(s)
      Tang Dewei、Fujinaga Masayuki、Hatori Akiko、Zhang Yiding、Yamasaki Tomoteru、Xie Lin、Mori Wakana、Kumata Katsushi、Liu Jianjun、Manning H. Charles、Huang Gang、Zhang Ming-Rong
    • Journal Title

      European Journal of Medicinal Chemistry

      Volume: 150 Pages: 1-8

    • DOI

      10.1016/j.ejmech.2018.02.076

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Journal Article] A useful PET probe [11C]BU99008 with ultra-high specific radioactivity for small animal PET imaging of I2-imidazoline receptors in the hypothalamus.2017

    • Author(s)
      Kawamura K, Shimoda Y, Yui J, Zhang Y, Yamasaki T, Wakizaka H, Hatori A, Xie L, Kumata K, Fujinaga M, Ogawa M, Kurihara Y, Nengaki N, Zhang MR.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 45 Pages: 1-7

    • DOI

      10.1016/j.nucmedbio.2016.10.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Journal Article] Developing new PET tracers to image the growth hormone secretagogue receptor 1a (GHS-R1a)2017

    • Author(s)
      Kawamura Kazunori、Fujinaga Masayuki、Shimoda Yoko、Yamasaki Tomoteru、Zhang Yiding、Hatori Akiko、Xie Lin、Wakizaka Hidekatsu、Kumata Katsushi、Ohkubo Takayuki、Kurihara Yusuke、Ogawa Masanao、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 52 Pages: 49-56

    • DOI

      10.1016/j.nucmedbio.2017.06.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Journal Article] Synthesis and in vitro evaluation of three novel radiotracers for imaging of metabotropic glutamate receptor subtype 2 in rat brain2017

    • Author(s)
      Kumata Katsushi、Yamasaki Tomoteru、Hatori Akiko、Zhang Yiding、Mori Wakana、Fujinaga Masayuki、Xie Lin、Okubo Takayuki、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 27 Pages: 3139-3143

    • DOI

      10.1016/j.bmcl.2017.05.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Development of a 18F-Labeled Radiotracer with Improved Brain Kinetics for Positron Emission Tomography Imaging of Translocator Protein (18 kDa) in Ischemic Brain and Glioma2017

    • Author(s)
      Fujinaga Masayuki、Luo Rui、Kumata Katsushi、Zhang Yiding、Hatori Akiko、Yamasaki Tomoteru、Xie Lin、Mori Wakana、Kurihara Yusuke、Ogawa Masanao、Nengaki Nobuki、Wang Feng、Zhang Ming-Rong
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 60 Pages: 4047-4061

    • DOI

      10.1021/acs.jmedchem.7b00374

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Journal Article] Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 22017

    • Author(s)
      Zhang Xiaofei、Kumata Katsushi、Yamasaki Tomoteru、Cheng Ran、Hatori Akiko、Ma Longle、Zhang Yiding、Xie Lin、Wang Lu、Kang Hye Jin、Sheffler Douglas J.、Cosford Nicholas D. P.、Zhang Ming-Rong、Liang Steven H.
    • Journal Title

      ACS Chemical Neuroscience

      Volume: 8 Pages: 1937-1948

    • DOI

      10.1021/acschemneuro.7b00098

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[ 11 C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([ 11 C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain2017

    • Author(s)
      Ma Yufei、Kumata Katsushi、Yui Joji、Zhang Yiding、Yamasaki Tomoteru、Hatori Akiko、Fujinaga Masayuki、Nengaki Nobuki、Xie Lin、Wang Hui、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 25 Pages: 1014-1021

    • DOI

      10.1016/j.bmc.2016.12.011

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.2016

    • Author(s)
      Yamasaki T, Fujinaga M, Kawamura K, Furutsuka K, Nengaki N, Shimoda Y, Shiomi S, Takei M, Hashimoto H, Yui J, Wakizaka H, Hatori A, Xie L, Kumata K, Zhang MR.
    • Journal Title

      J Neurosci

      Volume: 36 Pages: 375-384

    • DOI

      10.1523/jneurosci.2289-15.2016

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25861135, KAKENHI-PROJECT-25293269
  • [Journal Article] In vivo evaluation of a new 18F-labeled PET ligand, [18F]FEBU, for the imaging of I2-imidazoline receptors.2015

    • Author(s)
      Kawamura K, Shimoda Y, Kumata K, Fujinaga M, Yui J, Yamasaki T, Xie L, Hatori A, Wakizaka H, Kurihara Y, Ogawa M, Nengaki N, Zhang MR.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 42 Pages: 406-412

    • DOI

      10.1016/j.nucmedbio.2014.12.014

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Journal Article] Synthesis and evaluation of 4-halogeno-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-[11C]methylbenzamide for imaging of metabotropic glutamate 1 receptor in melanoma.2015

    • Author(s)
      Fujinaga M, Xie L, Yamasaki T, Yui J, Shimoda Y, Hatori A, Kumata K, Zhang Y, Nengaki N, Kawamura K, Zhang MR.
    • Journal Title

      J Med Chem.

      Volume: 58 Pages: 1513-1523

    • DOI

      10.1021/jm501845n

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Journal Article] Noninvasive quantification of metabotropic glutamate receptor type 1 with [¹¹C]ITDM: a small-animal PET study.2014

    • Author(s)
      Yamasaki T, Fujinaga M, Yui J, Ikoma Y, Hatori A, Xie L, Wakizaka H, Kumata K, Nengaki N, Kawamura K, Zhang MR.
    • Journal Title

      J Cereb Blood Flow Metab.

      Volume: 34 Pages: 606-612

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Journal Article] Visualization of acute liver damage induced by cycloheximide in rats using PET with [(18)F]FEDAC, a radiotracer for translocator protein (18 kDa).2014

    • Author(s)
      Hatori A, Yui J, Xie L, Yamasaki T, Kumata K, Fujinaga M, Wakizaka H, Ogawa M, Nengaki N, Kawamura K, Zhang MR.
    • Journal Title

      PLoS One.

      Volume: 9

    • DOI

      10.1371/journal.pone.0086625

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24790543
  • [Journal Article] Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe 18F-FITM.2014

    • Author(s)
      Xie L, Yui J, Fujinaga M, Hatori A, Yamasaki T, Kumata K, Wakizaka H, Furutsuka K, Takei M, Jin ZH, Furukawa T, Kawamura K, Zhang MR.
    • Journal Title

      Int J Cancer.

      Volume: in press Pages: 1852-1859

    • DOI

      10.1002/ijc.28842

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591827, KAKENHI-PROJECT-24790543, KAKENHI-PROJECT-25293269
  • [Journal Article] Translocator protein (18 kda), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease2012

    • Author(s)
      Xie L, Yui J, Hatori A, Yamasaki T, Kumata K, Wakizaka H, Yoshida Y, Fujinaga M, Kawamura K, Zhang MR
    • Journal Title

      Journal of hepatology

      Volume: 57 Pages: 1076-1082

    • DOI

      10.1016/j.jhep.2012.07.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790543
  • [Presentation] 11C-L-1MTrp-PETによるメラノーマ免疫化学療法における免疫応答判定2021

    • Author(s)
      謝 琳, Hu Kuan, 熊田 勝志, 脇坂 秀克, 張 一鼎, 念垣 信樹, 下川 卓志, 張 明栄
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07659
  • [Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021

    • Author(s)
      Hu Kuan, Xie Lin, Zhang Yiding, Hanyu Masayuki, Zhang Ming-Rong
    • Organizer
      第61回日本核医学会学術総会, 日本核医学会
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Development of a stable peptide-based PET tracer for detecting CD133-expressing cancer stem cells2021

    • Author(s)
      Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Obata Honoka , Nagatsu Kotaro , Suzuki Hisashi , Zhang Ming-Rong
    • Organizer
      第4回日本核医学会分科会放射線薬品科学研究会 第20回放射性医薬品・画像診断薬研究会
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021

    • Author(s)
      Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong:
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Presentation] TRT薬剤「211At-AITM」合成法の改良2021

    • Author(s)
      破入 正行, 峯岸 克行, 門間 あゆみ, 謝 琳, Hu Kuan, 張 一鼎, 藤永 雅之, 永津 弘太郎, 張 明栄
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07659
  • [Presentation] Whole-body PET Tracking of a D-dodecapeptide and its Radiotheranostic Potential for PD-L1 overexpressed tumors2021

    • Author(s)
      Hu Kuan, Xie Lin, Zhang Yiding, Hanyu Masayuki, Zhang Ming-Rong
    • Organizer
      SNMMI2021, Society of Nuclear Medicine and Molecular Imaging
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] PEGylation modulation of peptides promotes PET detection of cancers2021

    • Author(s)
      Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong
    • Organizer
      eSRS
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021

    • Author(s)
      Hu Kuan, Xie Lin, Yiding Zhang, Hanyu Masayuki, Zhang Ming-Rong
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07659
  • [Presentation] PET imaging of PD-L1 overexpressing tumors with a 68Ga labeled D-dodecapeptide2021

    • Author(s)
      Hu Kuan, Xie Lin, Hanyu Masayuki, Zhang Yiding, Zhang Ming-Rong
    • Organizer
      eSRS, Society of Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] In vivo PET imaging of cancer α5β1-integrin using a pegylated peptide2021

    • Author(s)
      Hu Kuan , 謝 琳 , 張 一鼎 , 破入 正行 , 張 明栄:
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Presentation] PET imaging of PD-L1 overexpressing tumors with a 68Ga labeled D-dodecapeptide2021

    • Author(s)
      Hu Kuan, Xie Lin, Hanyu Masayuki, Yiding Zhang, Zhang Ming-Rong
    • Organizer
      eSRS, Society of Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07659
  • [Presentation] Effective therapy against melanoma using 211At labeled small-molecule radiopharmaceutical 211At-AITM by targeting oncoprotein metabotropic glutamate receptor 12019

    • Author(s)
      Lin Xie, Masayuki Hanyu, Masayuki Fujinaga, Yiding Zhang, Hu Kuan, Katsuyuki Minegishi, Cuiping Jiang, Fuki Kurosawa, Yukie Morokoshi, Huizi Li, Sumitaka Hasegawa, Kotaro Nagatsu, Ming-Rong Zhang
    • Organizer
      WMIC2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] 転移性メラノーマに対する211At-AITMを標的アイソトープ治療薬としての実証2019

    • Author(s)
      謝 琳, 破入 正行, 藤永 雅之, 張 一鼎, 峯岸 克行, 李 惠子, 諸越 幸恵, 長谷川 純崇, 永津 弘太郎, 張 明栄
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] Develop a peptide-based PET radiotracer for imaging PD-L1 expression in cancer2019

    • Author(s)
      Hu Kuan, Lin Xie, Masayuki Hanyu, Yiding Zhang, Ming-Rong Zhang
    • Organizer
      ISRS2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] 重粒子線を用いたがん治療のための基礎研究:照射後の免疫応答に関する治療効果予測マーカーの探索2018

    • Author(s)
      黒澤 ふき, 謝 琳, 藤崎 真吾, 下川 卓志
    • Organizer
      フリーラジカルサマースクール2018 in Kusatsu
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] Development and radiotherapeutic effect of two novel I-131 or At-211 labelled radioprobes for melanoma with overexpressed metabotropic glutamate receptor 12018

    • Author(s)
      Masayuki Hanyu, Lin Xie, Masayuki Fujinaga, Yiding Zhang, Akiko Hatori, Yukie Morokoshi, Huizi Li, Katsuyuki Minegishi, Sumitaka Hasegawa, Kotaro Nagatsu, Ming-Rong Zhang
    • Organizer
      12th Congress of the World federation of Nuclear Medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] In vivo characterizations of [11C]BMS193885 and [11C]Desmethyl-BMS193885 as a PET tracer for neuropeptide Y Y1 receptors2018

    • Author(s)
      Kazunori Kawamura , Wakana Mori , Tomoteru Yamasaki , Yiding Zhang , Masayuki Fujinaga , Akiko Hatori , Lin Xie , Katsushi Kumata , Takayuki Ohkubo , Yusuke Kurihara , Masanao Ogawa , Nobuki Nengaki , Ming-Rong Zhang
    • Organizer
      12th World Congress of the World Federation of Nuclear medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Visualizing the dynamics of checkpoint protein IDO1 reveals host antitumor responses activated by a combination of immunotherapy and chemotherapy with 11C-L-1MTrp PET2018

    • Author(s)
      Lin Xie, Takashi Shimokawa, Yiding Zhang, Cuiping Jiang, Hidekatsu Wakizaka, Katsushi Kumata, Nobuki Nengaki, Ming-Rong Zhang
    • Organizer
      12th World Congress of the World Federation of Nuclear Medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] Development and radiotherapeutic effect of two novel I-131 or At-211 labelled radioprobes for melanoma with overexpressed metabotropic glutamate receptor 12018

    • Author(s)
      Masayuki Hanyu, Lin Xie, Masayuki Fujinaga, Yiding Zhang, Akiko Hatori, Yukie Morokoshi, Huizi Li, Katsuyuki Minegishi, Sumitaka Hasegawa, Kotaro Nagatsu, Ming-Rong Zhang
    • Organizer
      12th Congress of the World federation of Nuclear Medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] α線を用いたRI療法による担がんマウスの治療効果及び体内分布の評価2018

    • Author(s)
      張 一鼎, 破入 正行, 謝 琳, 藤永 雅之, 羽鳥 晶子, 諸越 幸恵, 李 惠子, 峯岸 克行, 長谷川 純崇, 永津 弘太郎, 張 明栄
    • Organizer
      フリーラジカルサマースクール2018 in Kusatsu
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] 小分子放射性薬剤211At-AITMの合成と評価2018

    • Author(s)
      破入 正行, 謝 琳, 藤永 雅之, 張 一鼎, 羽鳥 晶子, 峯岸 克行, 李 惠子, 諸越 幸恵, 長谷川 純崇, 永津 弘太郎, 張 明栄
    • Organizer
      第58回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] 小分子薬剤211At-AITMによる標的アイソトープ治療への実証2018

    • Author(s)
      謝 琳, 破入 正行, 張 一鼎, 羽鳥 晶子, 峯岸 克行, 李 惠子, 諸越 幸恵, 長谷川 純崇, 永津 弘太郎, 張 明栄
    • Organizer
      第58回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] PD-L1をターゲットするPET診断及びがん免疫治療用の新規標識ペプチドの開発研究2018

    • Author(s)
      Hu Kuan, 謝 琳, 破入 正行, 張 明栄
    • Organizer
      第2回日本核医学会分科会 放射性薬品科学研究会 第18回放射性医薬品・画像診断薬研究会
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Development of [11C]CMDC for PET imaging of metabotropic glutamate receptor 2 in the rat brain2017

    • Author(s)
      Katsushi Kumata, Yiding Zhang, Akiko Hatori, Tomoteru Yamasaki, Takayuki Ohkubo, Yusuke Kurihara, Masayuki Fujinaga, Lin Xie, Kazunori Kawamura, Ming-Rong Zhang
    • Organizer
      22nd International symposium on radiopharmaceutical science (ISRS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] TSPOリガンドによるラットの脳腫瘍モデル及び脳虚血モデルのPETイメージング2017

    • Author(s)
      張 一鼎, 藤永 雅之, 熊田 勝志, 羽鳥 晶子, 謝 琳, 山崎 友照, 張 明栄
    • Organizer
      Free Radical Summer School in TATEYAMA 2017
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] Synthesis and evaluation of a new 11C-labeled growth hormone secretagogue receptor 1a probe2017

    • Author(s)
      Kazunori Kawamura , Masayuki Fujinaga , Yoko Shimoda , Tomoteru Yamasaki , Yiding Zhang , Akiko Hatori , Lin Xie , Hidekatsu Wakizaka , Yusuke Kurihara , Takayuki Ohkubo , Masanao Ogawa , Nobuki Nengaki , Ming-Rong Zhang
    • Organizer
      22nd International symposium on radiopharmaceutical science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Brain PET study using [11C]BU99008 in Zucker fatty versus lean rats.2017

    • Author(s)
      Kazunori Kawamura , Tomoteru Yamasaki , Yiding Zhang , Hidekatsu Wakizaka , Akiko Hatori , Lin Xie , Masayuki Fujinaga , Ming-Rong Zhang
    • Organizer
      2017 World Molecular Imaging Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Identifying antitumor responses of IDO1-targeting combination immunotherapy through 11C-L-1MTrp based PET platform2017

    • Author(s)
      Lin Xie, Yiding Zhang, Cuiping Jiang, Hidekatsu Wakizaka, Katsushi Kumata, Nobuki Nengaki, Ming-Rong Zhang.
    • Organizer
      2017 World Molecular Imaging Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] 新規GHS-R1a選択的PET用プローブの開発と評価2017

    • Author(s)
      河村 和紀 , 藤永 雅之 , 下田 陽子 , 山崎 友照 , 張 一鼎 , 羽鳥 晶子 , 謝 琳 , 脇坂 秀克 , 栗原 雄祐 , 大久保 崇之 , 小川 政直 , 念垣 信樹 , 張 明栄
    • Organizer
      第57回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Synthesis and evaluation of radionuclide therapy probe for metabotropic glutamate receptor 1 in melanoma2017

    • Author(s)
      Masayuki Fujinaga, Lin Xie, Yiding Zhang, Masayuki Hanyu, Tomoteru Yamasaki, Akiko Hatori, Katsushi Kumata, Ming-Rong Zhang
    • Organizer
      22th International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      International Congress Center Dresden, Dresden, Germany
    • Year and Date
      2017-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Synthesis and radiotherapeutic effect of two I-131 or At-211 labelled radioprobes for melanoma with overexpressed metabotropic glutamate receptor 12017

    • Author(s)
      Masayuki Hanyu, Masayuki Fujinaga, Lin Xie, Yiding Zhang, Akiko Hatori, Katsuyuki Minegishi, Kotaro Nagatsu, Ming-Rong Zhang
    • Organizer
      10th International Symposium on Targeted Alpha Therapy
    • Place of Presentation
      石川県金沢市昭和町石川県立音楽堂
    • Year and Date
      2017-05-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] 免疫チェックポイント阻害薬・抗PD1抗体の動態評価 PETを用いた64Cu抗PD1抗体の可視化2017

    • Author(s)
      謝 琳, 破入 正行, 張 一鼎, 蒋 翠萍, 東 梨佳子, 鈴木 寿, 下川 卓志, 張 明栄.
    • Organizer
      第57回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K16495
  • [Presentation] 肥満ラットでの脳PET定量測定によるイミダゾリンI2受容体及びセロトニントランポーター結合の増加2016

    • Author(s)
      河村 和紀, 下田 陽子, 山崎 友照, 由井 譲二, 張 一鼎, 脇坂 秀克, 羽鳥 晶子, 謝 琳, 武井 誠, 張 明栄
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2016-11-05
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] 腫瘍に発現する代謝型グルタミン酸受容体1型を標的とする内用療法放射性プローブの開発2016

    • Author(s)
      藤永雅之、謝琳、張一鼎、山崎友照、羽鳥晶子、熊田勝志、張明栄
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      愛知県名古屋市熱田区名古屋国際会議場
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] PET imaging of a feeding center using [11C]BU99008 with ultra-high specific activity2015

    • Author(s)
      Kazunori Kawamura, Yoko Shimoda, Joji Yui, Yiding Zhang, Tomoteru Yamasaki, Hidekatsu Wakizaka, Masayuki Fujinaga, Katsushi Kumata, Lin Xie, Akiko Hatori, Masanao Ogawa, Yusuke Kurihara, Nobuki Nengaki, Ming-Rong Zhang.
    • Organizer
      Annual Congress of the European Association of Nuclear Medicine 2015
    • Place of Presentation
      Congress Center Hamburg, Hamburg, Germany
    • Year and Date
      2015-10-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Radiosynthesis and evaluation of [11C]BU99008 with ultra-high specific activity as a PET ligand for imaging I2-imidazoline receptors.2015

    • Author(s)
      Kazunori Kawamura , Yoko Shimoda , Joji Yui , Masayuki Fujinaga , Tomoteru Yamasaki , Akiko Hatori , Lin Xie , Yiding Zhang , Katsushi Kumata , Masanao Ogawa , Kurihara Yusuke , Nobuki Nengaki , Hidekatsu Wakizaka , Ming-Rong Zhang.
    • Organizer
      21st International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      University of Missouri, Columbia, MO, USA
    • Year and Date
      2015-05-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Development of 11C-IITM for imaging of metabotropic glutamate 1 receptor in melanoma2015

    • Author(s)
      Lin Xie, Masayuki Fujinaga, Tomoteru Yamasaki, Joji Yui, Akiko Hatori, Yiding Zhang, Nobuki Nengaki, Kazunori Kawamura, Ming-Rong Zhang
    • Organizer
      SNMMI 2015 Annual Meeting
    • Place of Presentation
      Baltimore, Maryland.USA
    • Year and Date
      2015-06-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] トランスロケータタンパク質(18kDa)、非アルコール性脂肪肝疾患診断の新たな分子イメージングバイオマーカー2013

    • Author(s)
      謝琳、由井譲二、羽鳥晶子、山崎友照、熊田勝志、脇坂秀克、吉田勇一郎、藤永雅之、河村和紀、張明栄
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24790543
  • [Presentation] メラノーマに過剰発現するmGlu1を標的とする[18F]FITM-PETイメージング2013

    • Author(s)
      謝琳、由井譲二、藤永雅之、羽鳥晶子、山崎友照、熊田勝志、脇坂秀克、念垣信樹、河村和紀、張明栄
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] First imaging of metabotropic glutamate 1 receptor in melanoma with a positron emission tomography probe 18F-FITM2013

    • Author(s)
      Lin Xie, Joji Yui, Masayuki Fujinaga, Akiko Hatori, Tomoteru Yamasaki, Hidekatsu Wakizaka, Kazunori Kawamura, Ming-Rong Zhang
    • Organizer
      SNMMI 2013 Annual Meeting
    • Place of Presentation
      カナダ、バンクーバー
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Molecular Imaging of Multiple Sclerosis and Non-alcoholic Fatty Liver Disease Using Translocator Protein (18 kDa) Radioligands2013

    • Author(s)
      Lin Xie
    • Organizer
      Advance in Probe Discovery for Neuroimaging and Targeted Radiotherapy
    • Place of Presentation
      中国、上海
    • Data Source
      KAKENHI-PROJECT-24790543
  • [Presentation] メラノーマに過剰発現する代謝型グルタミン酸1型受容体を標的とする[18F]FITM-PETイメージング2013

    • Author(s)
      謝琳、由井譲二、藤永雅之、羽鳥晶子、山崎友照、張明栄
    • Organizer
      第13回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Translocator Protein (18 kDa) is a Potential Biomarker for Molecular Imaging of Non-alcoholic Fatty Liver Disease2012

    • Author(s)
      Lin Xie, Joji Yui, Akiko Hatori, Tomoteru Yamasaki, Katsushi Kumata, Hidekatsu Wakizaka, Masayuki Fujinaga, Ming-Rong Zhang
    • Organizer
      世界分子イメージング学会2012年会 (2012WMIC)
    • Place of Presentation
      アイルランド、ダブリン
    • Data Source
      KAKENHI-PROJECT-24790543
  • [Presentation] TSPOを標的とした肝細胞癌の画像診断法の開発に関する研究2012

    • Author(s)
      謝 琳、由井 譲二、羽鳥 晶子、山崎 友照、熊田 勝志、脇坂 秀克、張 明栄
    • Organizer
      第52 回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24790543
  • [Presentation] [18F]FEDAC-PETによる非アルコール性脂肪肝疾患画像診断法の開発2012

    • Author(s)
      謝琳、由井譲二、羽鳥晶子、山崎友照、熊田勝志、脇坂秀克、張明栄
    • Organizer
      第12回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24790543
  • [Presentation] 腫瘍に発現する代謝型グルタミン酸受容体1をターゲットとするPETプローブの開発

    • Author(s)
      藤永雅之、謝 琳、山崎友照、由井譲二、熊田勝志、下田陽子、羽鳥晶子、念垣信樹、張明栄
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] ヒト肝臓検体を用いる脂肪肝に対する 18F-FEDACイメージングの有用性評価

    • Author(s)
      謝 琳、由井譲二、熊田勝志、羽鳥晶子、山崎友照、季斌、河村和紀、張明栄
    • Organizer
      第54回核医学会学術総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-24790543
  • [Presentation] イミダゾリンI2受容体イメージング用18F標識PET用プローブの開発

    • Author(s)
      河村和紀、下田陽子、山﨑友照、由井譲二、熊田勝志、藤永雅之、謝琳、羽鳥晶子、脇坂秀克、小川政直、張明栄
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪府立国際会議場(大阪)
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Oncoimaging of melanoma by targeted ectopic metabotropic glutamate 1 receptor with a positron emission tomography radioprobe 18F-FITM

    • Author(s)
      Lin Xie, Joji Yui, Masayuki Fujinaga, Akiko Hatori, Tomoteru Yamasaki, Katsushi Kumata, Hidekatsu Wakizaka, Kazunori Kawamura, Ming-Rong Zhang
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Identifying neuronal damage and neuroprotective effects in vivo by 11C-ITMM PET imaging

    • Author(s)
      Lin Xie, Joji Yui, Masayuki Fujinaga, Tomoteru Yamasaki, Akiko Hatori, Katsushi Kumata,Nobuki Nengaki, Ming-Rong Zhang
    • Organizer
      日中核医学交流合同シンポジウム in 沖縄
    • Place of Presentation
      メルキュールホテル沖縄那覇(沖縄県那覇市)
    • Year and Date
      2015-03-14 – 2015-03-15
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Synthesis and evaluation of 18F-labeled imidazoline I2 receptor ligand as a PET probe

    • Author(s)
      Kawamura K, Yamasaki T, Shimoda Y, Kumata K, Fujinaga M, Yui J, Xie L, Hatori A, Wakizaka H, Kurihara Y, Ogawa M, Nengaki N, Zhang MR
    • Organizer
      27th Annual Congress of the European Association of Nuclear Medicine
    • Place of Presentation
      Gothenburg, Sweden
    • Year and Date
      2014-10-18 – 2014-10-22
    • Data Source
      KAKENHI-PROJECT-26293283
  • 1.  Ming Rong Zhang (80443076)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 62 results
  • 2.  藤永 雅之 (70623726)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 42 results
  • 3.  山崎 友照 (80627563)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 40 results
  • 4.  KAWAMURA KAZUNORI (50401766)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 22 results
  • 5.  胡 寛 (00827678)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 6.  破入 正行 (80435552)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 7.  HATORI Akiko (20531528)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 8.  水野 真盛 (40271506)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MINAMIMOTO Takafumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  金 朝暉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  古川 高子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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