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Zhang Ming-Rong  張 明栄

… Alternative Names

ZHANG Ming-Rong  張 明栄

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Researcher Number 80443076
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-9500-0868
Affiliation (Current) 2022: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所 先進核医学基盤研究部, 部長
Affiliation (based on the past Project Information) *help 2021 – 2022: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所 先進核医学基盤研究部, 部長
2019 – 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 先進核医学基盤研究部, 部長(定常)
2016 – 2018: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 標識薬剤開発部, 部長(定常)
2016: 国立研究開発法人量子科学技術研究開発機構, 標識薬剤開発部, 部長
2015: 国立研究開発法人放射線医学総合研究所, 分子イメージング研究センター, プログラムリーダー … More
2015: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, チームリーダー
2012 – 2014: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, プログラムリーダー
2013: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター分子認識研究プログラム, プログラムリーダー
2010 – 2011: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, チームリーダー
2009: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター・分子認識研究グループ, チームリーダー
2007 – 2008: National Institute of Radiological Sciences, 分子イメージング研究センター, チームリーダー
2007: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター分子認識研究グループ, チームリーダー Less
Review Section/Research Field
Principal Investigator
Radiation science / Drug development chemistry / Basic Section 52040:Radiological sciences-related
Except Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related / Physical pharmacy
Keywords
Principal Investigator
PET / 分子イメージング / 核医学 / mGluR1 / オートラジオグラフィ / AC-5216 / SPECT / 末梢性ベンゾジアゼピン受容体 / アルツハイマー病 / 末梢性ベンゾジアゾピン受容体 … More / PBR / [11C]DAA1106 / [11C]AC-5216 / [18F]FEDAA1106 / 放射性医薬品 / 造影剤PETイメージング剤 / 脳疾患 / 腫瘍 / 放射性プローブ / 代謝型グルタミン酸受容体 / mGluR2 / PETプローブ / 代謝型グルタミン酸受容体サブタイプ2 / [11C]DMTN / 画像化 / 膜貫通AMPA受容体調節性タンパク質-γ8 / AMPA受容体 / オートラジオグラフィー / 膜貫通AMPA受容体調節性タンパク質 … More
Except Principal Investigator
PET / 放射線 / PET imaging / 18F / 核医学 / 64Cu / 末梢性BZ受容体 / グリア細胞 / 心筋 / PK-11195 / Ro5-4864 / PETプローブ用マイクロダイアリシス法 / 脂肪族ケトン体 / ^<18>F-FEDAC / PK11195 / NMDA / キノリン酸 / ミクログリア / 酸素代謝 / 糖代謝 / 脳血流 / 神経保護作用 / 14C-酢酸 / 興奮性アミノ酸 / 超高比放射能 / モルヒネ / 鎮痛作用 / diprenorphine / ポジトロン / インビボ / インビトロ / ポジトロン核種 / 拮抗剤 / 超微量 / ストレス誘発性 / 神経科学 / イメージング / 生理活性 / Benzyl acetate / glia / protracer / washout rate / developing / status epilepsy / alpha5beta1 integrin / Fluorine-18 / Fibronectin / Radioprobe / 分子イメージング / 摂食 / 肥満 / イミダゾリン受容体 / グレリン受容体 / 分子イメージング / イミダゾリンI2受容体 / 肥満症 / グルタミン酸受容体 / 神経変性疾患 / ポジトロンCT / 脳神経疾患 / 被曝線量 / モノアシルグリセロールリパーゼ / MAGL / ポジトロン エミッション トモグラフィ / PETプローブ / ポジトロン エミッション トモグラフィー / 画像化 / 膵がん / 光線力学的療法 / 光感受性物質 / フッ素-18 / 炭素-11 / 11C / BODIPY / stapled peptide / radiotheranostics / intracellular protein / cancer / radionuclide therapy / intracellular delivery / 代謝型グルタミン酸受容体1型 / Radio-theranostics / PET診断薬 / α線治療薬 / mGluR1 / PET診断 / TRT治療 Less
  • Research Projects

    (17 results)
  • Research Products

    (186 results)
  • Co-Researchers

    (42 People)
  •  難治性胆管がんの代謝を利用した新規放射性治療薬開発

    • Principal Investigator
      吉井 幸恵
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Stapled peptide-based radiotheranostics for intracellular protein-protein interactions targeted cancer imaging and therapy

    • Principal Investigator
      胡 寛
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  mGluR1を標的とするα線Radio-theranosticsシステムの確立

    • Principal Investigator
      謝 琳
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Development of PET probes for gama 8-dependent transmembrane AMPA receptor regulatory proteinPrincipal Investigator

    • Principal Investigator
      張 明栄
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Development of imaging method for early pancreatic cancer by high-resolution PET using radiolabeled antibody

    • Principal Investigator
      Yoshii Yukie
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  新規PET用トレーサーを用いた光線力学的療法の安全性及び治療効果評価手法の構築

    • Principal Investigator
      河村 和紀
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Visualization of monoacylglycerol lipase in ischemia rat brain using [11C]SAR127303 and development of new PET probes.

    • Principal Investigator
      HATORI Akiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of novel PET probes for imaging of metabotropic glutamate receptor subtype 2Principal Investigator

    • Principal Investigator
      Zhang Ming-Rong
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of imaging agents for feeding function as a diagnostic tool and evaluation of drug therapy for obesity

    • Principal Investigator
      KAWAMURA KAZUNORI
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of radioprobes by targeted metabotropic glutamate receptor 1 in tumorPrincipal Investigator

    • Principal Investigator
      Ming Rong Zhang
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of peptide-based PET probe targeting integrin alpha5beta1

    • Principal Investigator
      JIN Zhao-Hui
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences
  •  Molecular imaging of metablotropic glutamate receptor type 1 &#8211; a first-in-human study

    • Principal Investigator
      ISHIWATA Kiichi
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Evaluation of 14C(11C)-Benzyl acetate as a potential probe for the measurement of glial metabolism.

    • Principal Investigator
      INOUE Osamu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Osaka University
  •  Development of Novel PET Probes for Metabotropic Glutamate Receptor Subtype 1 (mGluR1)Principal Investigator

    • Principal Investigator
      MING-RONG Zhang
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences
  •  Study on functional roles of PBR (TSPO) in glia and myocardium

    • Principal Investigator
      INOUE Osamu
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Osaka University
  •  Development of PET, SPECT and Fluorescence Probes for Imaging of Peripheral Benzodiazepine ReceptorsPrincipal Investigator

    • Principal Investigator
      ZHANG Ming-rong
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      National Institute of Radiological Sciences
  •  超高比放射能標識リガンドによる生体超微量現象の解明

    • Principal Investigator
      井上 修
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Physical pharmacy
    • Research Institution
      Osaka University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] Positron Emission Tomography (PET) Imaging of Metabotropic Glutamate Receptor Subtype 2 (mGlu2) Based on a Negative Allosteric Modulator Radioligand.2021

    • Author(s)
      Xiaofei Zhang, Zhiwei Xiao, Kumata Katsushi, Yamasaki Tomoteru, Lee Josephson, Zhang Ming-Rong, Wang Lu, Steven H. Liang
    • Total Pages
      314
    • Publisher
      Humana, New York, NY
    • ISBN
      9781071611074
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Book] Attempts to Image MRP1 Function in the Blood-Brain Barrier Using the Metabolite Extrusion Method2020

    • Author(s)
      Toshimitsu Okamura, Tatsuya Kikuchi, Ming-Rong Zhang
    • Total Pages
      1132
    • Publisher
      Springer, Cham
    • ISBN
      9783030531768
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Journal Article] A multifunctional nanotheranostic agent potentiates erlotinib to EGFR wild-type non-small cell lung cancer2022

    • Author(s)
      Wang Duo、Zhou Jun、Fang Weimin、Huang Cuiqing、Chen Zerong、Fan Meng、Zhang Ming-Rong、Xiao Zeyu、Hu Kuan、Luo Liangping
    • Journal Title

      Bioactive Materials

      Volume: 13 Pages: 312-323

    • DOI

      10.1016/j.bioactmat.2021.10.046

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Journal Article] Whole-body PET tracking of a d-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors2022

    • Author(s)
      Hu Kuan, Wu Wenyu, Xie Lin, Geng Hao, Zhang Yiding, Hanyu Masayuki, Zhang Lulu, Liu Yinghuan, Nagatsu Kotaro, Suzuki Hisashi, Guo Jialin, Wu Yundong, Li Zigang, Wang Feng, Zhang Ming-Rong
    • Journal Title

      Acta Pharmaceutica Sinica B

      Volume: 12 Pages: 1363-1376

    • DOI

      10.1016/j.apsb.2021.09.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714
  • [Journal Article] Automated radiosynthesis of [11C]MTP38- a phosphodiesterase 7 imaging tracer- using [11C]hydrogen cyanide for clinical applications2022

    • Author(s)
      Kawamura Kazunori、Hashimoto Hiroki、Ohkubo Takayuki、Hanyu Masayuki、Ogawa Masanao、Nengaki Nobuki、Arashi Daisuke、Kurihara Yusuke、Fujishiro Tomoya、Togashi Takahiro、Sakai Toshiyuki、Muto Masatoshi、Takei Makoto、Ishii Hideki、Saijo Takeaki、Matsumura Takehiko、Obokata Naoyuki、Zhang Ming‐Rong
    • Journal Title

      Journal of Labelled Compounds and Radiopharmaceuticals

      Volume: 65 Pages: 140-146

    • DOI

      10.1002/jlcr.3965

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19H03610, KAKENHI-PROJECT-20H03635
  • [Journal Article] Upregulation of striatal metabotropic glutamate receptor subtype 1 (mGluR1) in rats with excessive glutamate release induced by N-acetylcysteine2022

    • Author(s)
      Yamasaki Tomoteru, Okada Maki, Hiraishi Atsuto, Mori Wakana, Zhang Yiding, Fujinaga Masayuki, Wakizaka Hidekatsu, Kurihara Yusuke, Nengaki Nobuki, Zhang Ming-Rong
    • Journal Title

      Neurotoxicity Research

      Volume: 40 Pages: 26-35

    • DOI

      10.1007/s12640-021-00449-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Journal Article] Peptide-based nanomaterials: Self-assembly, properties and applications2022

    • Author(s)
      Li Tong、Lu Xian-Mao、Zhang Ming-Rong、Hu Kuan、Li Zhou
    • Journal Title

      Bioactive Materials

      Volume: 11 Pages: 268-282

    • DOI

      10.1016/j.bioactmat.2021.09.029

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Journal Article] Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold2021

    • Author(s)
      Rong Jian, Mori Wakana, Xia Xiaotian, Zhang Ming-Rong, Liang Steven
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 64 Pages: 14283-14298

    • DOI

      10.1021/acs.jmedchem.1c00747

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21K07659
  • [Journal Article] Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetylindole Derivatives as Novel Positron-Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain2021

    • Author(s)
      Hattori Yasushi, Yamasaki Tomoteru, Ohashi Tomohiro, Miyanohana Yuhei, Kusumoto Tomokazu, Maeda Ryouta, Miyamoto Maki, Debori Yasuyuki, Hata Akito, Zhang Yiding, Wakizaka Hidekatsu, Wakabayashi Takeshi, Fujinaga Masayuki, Yamashita Ryo, Zhang Ming-Rong, Koike Tatsuki
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 64 Pages: 11990-12002

    • DOI

      10.1021/acs.jmedchem.1c00584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Journal Article] Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study2021

    • Author(s)
      Yamasaki Tomoteru, Hatori Akiko, Zhang Yiding, Kurihara Yusuke, Ogawa Masanao, Wakizaka Hidekatsu, Rong Jian, Wang Lu, Huan Liang, Zhang Ming-Rong
    • Journal Title

      Theranostics

      Volume: 11 Pages: 9492-9502

    • DOI

      10.7150/thno.64320

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Journal Article] Imaging the trace amine-associated receptor 1 by positron emission tomography2021

    • Author(s)
      Sun Jiyun, Chen Jiahui, Kumata Katsushi, Xiao Zhiwei, Rong Jiang, Haider Ahmed, Shao Tuo, Wang Lu, Xu Hao, Zhang Ming-Rong, Liang Steven
    • Journal Title

      Tetrahedron Letters

      Volume: 70 Pages: 153007-153007

    • DOI

      10.1016/j.tetlet.2021.153007

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Journal Article] Development of a Stable Peptide-Based PET Tracer for Detecting CD133-Expressing Cancer Cells2021

    • Author(s)
      Hu Kuan、Ma Xiaohui、Xie Lin、Zhang Yiding、Hanyu Masayuki、Obata Honoka、Zhang Lulu、Nagatsu Kotaro、Suzuki Hisashi、Shi Rui、Wang Weizhi、Zhang Ming-Rong
    • Journal Title

      ACS Omega

      Volume: 7 Pages: 334-341

    • DOI

      10.1021/acsomega.1c04711

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714
  • [Journal Article] Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping2021

    • Author(s)
      Chen Zhen, Wakana Mori, Rong Jian, Schafroth Michael A, Ogasawara Daisuke, Yamasaki Tomoteru, Hiraishi Atsuto, Hatori Akiko, Zhang Yiding, Hu Kuan, Fujinaga Masayuki, Cravatt Benjamin F., Josephson Lee, Zhang Ming-Rong, Liang Steven
    • Journal Title

      Acta Pharmaceutica Sinica B

      Volume: 11 Pages: 1686-1695

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Journal Article] Radiosynthesis of 18F-fluoroethylated tracers via a simplified one-pot 18F-fluoroethylation method using [18F]fluoroethyl tosylate2021

    • Author(s)
      Kawamura Kazunori、Kumata Katsushi、Mori Wakana、Fujinaga Masayuki、Kurihara Yusuke、Ogawa Masanao、Ohkubo Takayuki、Furutsuka Kenji、Hashimoto Hiroki、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 169 Pages: 109571-109571

    • DOI

      10.1016/j.apradiso.2020.109571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03610
  • [Journal Article] Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin2021

    • Author(s)
      Ohkubo Takayuki、Kurihara Yusuke、Ogawa Masanao、Nengaki Nobuki、Fujinaga Masayuki、Mori Wakana、Kumata Katsushi、Hanyu Masayuki、Furutsuka Kenji、Hashimoto Hiroki、Kawamura Kazunori、Zhang Ming-Rong
    • Journal Title

      EJNMMI Radiopharmacy and Chemistry

      Volume: 6 Pages: 23-23

    • DOI

      10.1186/s41181-021-00138-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19H03610, KAKENHI-PROJECT-20H03635
  • [Journal Article] Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping2021

    • Author(s)
      Chen Zhen、Mori Wakana、Rong Jian、Schafroth Michael A.、Shao Tuo、Van Richard S.、Ogasawara Daisuke、Yamasaki Tomoteru、Hiraishi Atsuto、Hatori Akiko、Chen Jiahui、Zhang Yiding、Hu Kuan、Fujinaga Masayuki、Sun Jiyun、Yu Qingzhen、Collier Thomas L.、et al.
    • Journal Title

      Acta Pharmaceutica Sinica B

      Volume: In press Pages: 1686-1695

    • DOI

      10.1016/j.apsb.2021.01.021

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-21H02873
  • [Journal Article] Off-tumor IDO1 target engagements determine the cancer-immune set point and predict the immunotherapeutic efficacy2021

    • Author(s)
      Xie Lin, Hu Kuan, Duo Yanhong, Shimokawa Takashi, Kumata Katsushi, Zhang Yiding, Jiang Cuiping, Zhang Lulu, Nengaki Nobuki, Wakizaka Hidekatsu, Cao Yihai, Zhang Ming-Rong
    • Journal Title

      Journal for ImmunoTherapy of Cancer

      Volume: 9

    • DOI

      10.1136/jitc-2021-002616

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21K07659
  • [Journal Article] 211At-Labeled Polymer Nanoparticles for Targeted Radionuclide Therapy of Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR)-Overexpressed Cancer2021

    • Author(s)
      Shi Xiumin、Li Qing、Zhang Lulu、Hanyu Masayuki、Xie Lin、Hu Kuan、Nagatsu Kotaro、Zhang Chuan、Wu Zhengcan、Wang Feng、Zhang Ming-Rong、Yang Kai、Zhu Ran
    • Journal Title

      Bioconjugate Chemistry

      Volume: 32 Pages: 1763-1772

    • DOI

      10.1021/acs.bioconjchem.1c00263

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659
  • [Journal Article] Synthesis and evaluation of 6-(11C-methyl(4-(pyridin-2-yl)thiazol-2-yl)amino)benzo[d]thiazol-2(3H)-one for imaging γ-8 dependent transmembrane AMPA receptor regulatory protein by PET2020

    • Author(s)
      Yu Qingzhen、Kumata Katsushi、Li Hua、Zhang Yiding、Chen Zhen、Zhang Xiaofei、Shao Tuo、Hatori Akiko、Yamasaki Tomoteru、Xie Lin、Hu Kuan、Wang Gangqiang、Josephson Lee、Sun Shaofa、Zhang Ming-Rong、Liang Steven H.
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 30 Pages: 126879-126879

    • DOI

      10.1016/j.bmcl.2019.126879

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2)2020

    • Author(s)
      Yamasaki Tomoteru、Zhang Xiaofei、Kumata Katsushi、Zhang Yiding、Deng Xiaoyun、Fujinaga Masayuki、Chen Zhen、Mori Wakana、Hu Kuan、Wakizaka Hidekatsu、Hatori Akiko、Xie Lin、Ogawa Masanao、Nengaki Nobuki、Van Richard、Shao Yihan、Sheffler Douglas J.、Cosford Nicholas D. P.、Liang Steven H.、Zhang Ming-Rong
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 63 Pages: 11469-11483

    • DOI

      10.1021/acs.jmedchem.9b01991

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators2020

    • Author(s)
      Sun Ji-yun、Kumata Katsushi、Chen Zhen、Zhang Yi-ding、Chen Jia-hui、Hatori Akiko、Fu Hua-long、Rong Jian、Deng Xiao-yun、Yamasaki Tomoteru、Xie Lin、Hu Kuan、Fujinaga Masayuki、Yu Qing-zhen、Shao Tuo、Collier Thomas Lee、Josephson Lee、Shao Yi-han、Du Yun-fei、Wang Lu、Xu Hao、Zhang Ming-rong、Liang Steven H
    • Journal Title

      Acta Pharmacologica Sinica

      Volume: 42 Pages: 491-498

    • DOI

      10.1038/s41401-020-0456-9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled -amino acid oxidase (DAAO) inhibitor for PET imaging2020

    • Author(s)
      Deng Xiaoyun、Zhang Yiding、Chen Zhen、Kumata Katsushi、Van Richard、Rong Jian、Shao Tuo、Hatori Akiko、Mori Wakana、Yu Qingzhen、Hu Kuan、Fujinaga Masayuki、Wey Hsiao-Ying、Shao Yihan、Josephson Lee、Murtas Giulia、Pollegioni Loredano、Zhang Ming-Rong、Liang Steven
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 30 Pages: 127326-127326

    • DOI

      10.1016/j.bmcl.2020.127326

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Radiosynthesis and evaluation of 4-(6-[18F]Fluoro-4-(5-isopropoxy-1H-indazol-3-yl)pyridin-2-yl)morpholine as a novel radiotracer candidate targeting leucine-rich repeat kinase 22020

    • Author(s)
      Mori Wakana、Yamasaki Tomoteru、Hattori Yasushi、Zhang Yiding、Kumata Katsushi、Fujinaga Masayuki、Hanyu Masayuki、Nengaki Nobuki、Zhang Hong、Zhang Ming-Rong
    • Journal Title

      RSC Medicinal Chemistry

      Volume: 11 Pages: 676-684

    • DOI

      10.1039/c9md00590k

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-20H03635
  • [Journal Article] Synthesis and preliminary studies of 11C-labeled tetrahydro-1,7-naphthyridine-2-carboxamides for PET imaging of metabotropic glutamate receptor 22020

    • Author(s)
      Zhang Xiaofei、Zhang Yiding、Chen Zhen、Shao Tuo、Van Richard、Kumata Katsushi、Deng Xiaoyun、Fu Hualong、Yamasaki Tomoteru、Rong Jian、Hu Kuan、Hatori Akiko、Xie Lin、Yu Qingzhen、Ye Weijian、Xu Hao、Sheffler Douglas J.、Cosford Nicholas D. P.、Shao Yihan、Tang Pingping、Wang Lu、Zhang Ming-Rong、Liang Steven H.
    • Journal Title

      Theranostics

      Volume: 10 Pages: 11178-11196

    • DOI

      10.7150/thno.42587

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer [11C]DFMC2020

    • Author(s)
      Yamasaki Tomoteru、Ohya Tomoyuki、Mori Wakana、Zhang Yiding、Wakizaka Hidekatsu、Nengaki Nobuki、Fujinaga Masayuki、Kikuchi Tatsuya、Zhang Ming-Rong
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics

      Volume: - Pages: 353-360

    • DOI

      10.1124/jpet.119.263772

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08240, KAKENHI-PROJECT-20H03635
  • [Journal Article] 3-(Cyclopropylmethyl)-7-((4-(4-[11C]methoxyphenyl)piperidin-1-yl)methyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine: Synthesis and preliminary evaluation for PET imaging of metabotropic glutamate receptor subtype 22020

    • Author(s)
      Kumata Katsushi、Zhang Yiding、Ogawa Masanao、Kurihara Yusuke、Mori Wakana、Hu Kuan、Fujinaga Masayuki、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 30 Pages: 127555-127555

    • DOI

      10.1016/j.bmcl.2020.127555

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
  • [Journal Article] Synthesis and evaluation of 4-(2-fluoro-4-[11C]methoxyphenyl)-5-((2-methylpyridin-4-yl)methoxy)picolinamide for PET imaging of the metabotropic glutamate receptor 2 in the rat brain2019

    • Author(s)
      Kumata Katsushi、Hatori Akiko、Yamasaki Tomoteru、Zhang Yiding、Mori Wakana、Fujinaga Masayuki、Xie Lin、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 27 Pages: 483-491

    • DOI

      10.1016/j.bmc.2018.12.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Design, synthesis, and evaluation of 18F-labeled monoacylglycerol lipase inhibitors as novel positron emission tomography probes2019

    • Author(s)
      Chen Zhen, Mori Wakana, Zhang Ming-Rong, Liang Steven H. et al
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 62 Pages: 8866-8872

    • DOI

      10.1021/acs.jmedchem.9b00936

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K10461
  • [Journal Article] 131I-IITM and 211At-AITM: Two Novel Small-Molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 12019

    • Author(s)
      Xie Lin、Hanyu Masayuki、Fujinaga Masayuki、Zhang Yiding、Hu Kuan、Minegishi Katsuyuki、Jiang Cuiping、Kurosawa Fuki、Morokoshi Yukie、Li Huizi Keiko、Hasegawa Sumitaka、Nagatsu Kotaro、Zhang Ming-Rong
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 61 Pages: 242-248

    • DOI

      10.2967/jnumed.119.230946

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
  • [Journal Article] Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[11C]carboxylate2019

    • Author(s)
      Mori Wakana、Hatori Akiko、Zhang Yiding、Kurihara Yusuke、Yamasaki Tomoteru、Xie Lin、Kumata Katsushi、Hu Kuan、Fujinaga Masayuki、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 27 Pages: 3568-3573

    • DOI

      10.1016/j.bmc.2019.06.037

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K10461, KAKENHI-PROJECT-17K16495
  • [Journal Article] Design, synthesis, and evaluation of reversible and irreversible monoacylglycerol lipase positron emission tomography (PET) tracers using a “Tail Switching” strategy on a piperazinyl azetidine skeleton2019

    • Author(s)
      Chen Zhen、Mori Wakana、Deng Xiaoyun、Cheng Ran、Ogasawara Daisuke、Zhang Genwei、Schafroth Michael A.、Dahl Kenneth、Fu Hualong、Hatori Akiko、Shao Tuo、Zhang Yiding、Yamasaki Tomoteru、Zhang Xiaofei、Rong Jian、Yu Qingzhen、Hu Kuan、Fujinaga Masayuki、Xie Lin、Kumata Katsushi、Gou Yuancheng、Chen Jingjin、Gu Shuyin
    • Journal Title

      Jounal of Medicinal Chemistry

      Volume: 62 Pages: 3336-3353

    • DOI

      10.1021/acs.jmedchem.8b01778

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10461, KAKENHI-PROJECT-18H06217, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
  • [Journal Article] Correction: Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation2019

    • Author(s)
      Hu Kuan、Hanyu Masayuki、Xie Lin、Zhang Yiding、Nagatsu Kotaro、Suzuki Hisashi、Zhang Ming-Rong
    • Journal Title

      Chemical Communications

      Volume: 55 Pages: 4273-4273

    • DOI

      10.1039/c9cc90113b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] [18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18 kDa)2018

    • Author(s)
      Kumata Katsushi、Zhang Yiding、Fujinaga Masayuki、Ohkubo Takayuki、Mori Wakana、Yamasaki Tomoteru、Hanyu Masayuki、Xie Lin、Hatori Akiko、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 26 Pages: 4817-4822

    • DOI

      10.1016/j.bmc.2018.08.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-17H04267
  • [Journal Article] First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [11C]SAR1273032018

    • Author(s)
      Yamasaki Tomoteru、Mori Wakana、Zhang Yiding、Hatori Akiko、Fujinaga Masayuki、Wakizaka Hidekatsu、Kurihara Yusuke、Wang Lu、Nengaki Nobuki、Ohya Tomoyuki、Liang Steven H.、Zhang Ming-Rong
    • Journal Title

      NeuroImage

      Volume: 176 Pages: 313-320

    • DOI

      10.1016/j.neuroimage.2018.05.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19870, KAKENHI-PROJECT-17K10461
  • [Journal Article] Change in the Binding of [11C]BU99008 to Imidazoline I2 Receptor Using Brain PET in Zucker Rats2018

    • Author(s)
      Kawamura Kazunori、Yamasaki Tomoteru、Zhang Yiding、Wakizaka Hidekatsu、Hatori Akiko、Xie Lin、Fujinaga Masayuki、Zhang Ming-Rong
    • Journal Title

      Molecular Imaging and Biology

      Volume: 印刷中

    • DOI

      10.1007/s11307-018-1206-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Journal Article] First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [11C]SAR1273032018

    • Author(s)
      Tomoteru Yamasaki, Wakana Mori, Yiding Zhang, Akiko Hatori, Masayuki Fujinaga, Hidekatsu Wakizaka, Yusuke Kurihara, Lu Wang, Nobuki Nengaki, Tomoyuki Ohya, Steven H Liang, Ming-Rong Zhang
    • Journal Title

      NeuroImage

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10461
  • [Journal Article] In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies2018

    • Author(s)
      Ran Cheng, Wakana Mori, Longle Ma, Mireille Alhouayek, Akiko Hatori, Yiding Zhang, Daisuke Ogasawara, Gengyang Yuan, Zhen Chen, Xiaofei Zhang, Hang Shi, Tomoteru Yamasaki, Lin Xie, Katsushi Kumata, Masayuki Fujinaga, Yuji Nagai, Takafumi Minamimoto, Mona Svensson, Lu Wang, Yunfei Du, Mary Jo Ondrechen, Neil Vasdev
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 61 Pages: 2278-2291

    • DOI

      10.1021/acs.jmedchem.7b01400

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10461, KAKENHI-PLANNED-15H05917
  • [Journal Article] Development of 2-(2-(3-(4-([18F]Fluoromethoxy-d2)phenyl)-7-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-4-isopropoxyisoindoline-1,3-dione for Positron-Emission-Tomography Imaging of Phosphodiesterase 10A in the Brain2018

    • Author(s)
      Mori Wakana、Yamasaki Tomoteru、Fujinaga Masayuki、Ogawa Masanao、Zhang Yiding、Hatori Akiko、Xie Lin、Kumata Katsushi、Wakizaka Hidekatsu、Kurihara Yusuke、Ohkubo Takayuki、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 62 Pages: 688-698

    • DOI

      10.1021/acs.jmedchem.8b01366

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain2018

    • Author(s)
      Fujinaga Masayuki、Kumata Katsushi、Zhang Yiding、Hatori Akiko、Yamasaki Tomoteru、Mori Wakana、Ohkubo Takayuki、Xie Lin、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 16 Pages: 8325-8335

    • DOI

      10.1039/c8ob01700j

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-17H04267
  • [Journal Article] A useful PET probe [11C]BU99008 with ultra-high specific radioactivity for small animal PET imaging of I2-imidazoline receptors in the hypothalamus.2017

    • Author(s)
      Kawamura K, Shimoda Y, Yui J, Zhang Y, Yamasaki T, Wakizaka H, Hatori A, Xie L, Kumata K, Fujinaga M, Ogawa M, Kurihara Y, Nengaki N, Zhang MR.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 45 Pages: 1-7

    • DOI

      10.1016/j.nucmedbio.2016.10.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Journal Article] Developing new PET tracers to image the growth hormone secretagogue receptor 1a (GHS-R1a)2017

    • Author(s)
      Kawamura Kazunori、Fujinaga Masayuki、Shimoda Yoko、Yamasaki Tomoteru、Zhang Yiding、Hatori Akiko、Xie Lin、Wakizaka Hidekatsu、Kumata Katsushi、Ohkubo Takayuki、Kurihara Yusuke、Ogawa Masanao、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 52 Pages: 49-56

    • DOI

      10.1016/j.nucmedbio.2017.06.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Journal Article] Synthesis and in vitro evaluation of three novel radiotracers for imaging of metabotropic glutamate receptor subtype 2 in rat brain2017

    • Author(s)
      Kumata Katsushi、Yamasaki Tomoteru、Hatori Akiko、Zhang Yiding、Mori Wakana、Fujinaga Masayuki、Xie Lin、Okubo Takayuki、Nengaki Nobuki、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 27 Pages: 3139-3143

    • DOI

      10.1016/j.bmcl.2017.05.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 22017

    • Author(s)
      Zhang Xiaofei、Kumata Katsushi、Yamasaki Tomoteru、Cheng Ran、Hatori Akiko、Ma Longle、Zhang Yiding、Xie Lin、Wang Lu、Kang Hye Jin、Sheffler Douglas J.、Cosford Nicholas D. P.、Zhang Ming-Rong、Liang Steven H.
    • Journal Title

      ACS Chemical Neuroscience

      Volume: 8 Pages: 1937-1948

    • DOI

      10.1021/acschemneuro.7b00098

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[ 11 C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([ 11 C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain2017

    • Author(s)
      Ma Yufei、Kumata Katsushi、Yui Joji、Zhang Yiding、Yamasaki Tomoteru、Hatori Akiko、Fujinaga Masayuki、Nengaki Nobuki、Xie Lin、Wang Hui、Zhang Ming-Rong
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 25 Pages: 1014-1021

    • DOI

      10.1016/j.bmc.2016.12.011

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Journal Article] Age and gender effects of 11C-ITMM binding to metabotropic glutamate receptor type 1 in healthy human participants.2017

    • Author(s)
      Sakata M, Toyohara J, Ishibashi K, Wagatsuma K, Ishii K, Zhang MR, Ishiwata K
    • Journal Title

      Neurobiol. Aging

      Volume: 55 Pages: 72-77

    • DOI

      10.1016/j.neurobiolaging.2017.03.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293269, KAKENHI-PROJECT-25293271
  • [Journal Article] Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.2016

    • Author(s)
      Yamasaki T, Fujinaga M, Kawamura K, Furutsuka K, Nengaki N, Shimoda Y, Shiomi S, Takei M, Hashimoto H, Yui J, Wakizaka H, Hatori A, Xie L, Kumata K, Zhang MR.
    • Journal Title

      J Neurosci

      Volume: 36 Pages: 375-384

    • DOI

      10.1523/jneurosci.2289-15.2016

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25861135, KAKENHI-PROJECT-25293269
  • [Journal Article] Relationship between type 1 metabotropic glutamate receptors and cerebellar ataxia2016

    • Author(s)
      Ishibashi K, Miura Y, Ishikawa K, Zhang MR, Toyohara J, Ishiwata K, Ishii K.
    • Journal Title

      Journal of Neurology

      Volume: 263 Pages: 2179-2187

    • DOI

      10.1007/s00415-016-8248-3

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293269, KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-15K19503
  • [Journal Article] In vivo evaluation of a new 18F-labeled PET ligand, [18F]FEBU, for the imaging of I2-imidazoline receptors.2015

    • Author(s)
      Kawamura K, Shimoda Y, Kumata K, Fujinaga M, Yui J, Yamasaki T, Xie L, Hatori A, Wakizaka H, Kurihara Y, Ogawa M, Nengaki N, Zhang MR.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 42 Pages: 406-412

    • DOI

      10.1016/j.nucmedbio.2014.12.014

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Journal Article] Synthesis and evaluation of 4-halogeno-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-[11C]methylbenzamide for imaging of metabotropic glutamate 1 receptor in melanoma.2015

    • Author(s)
      Fujinaga M, Xie L, Yamasaki T, Yui J, Shimoda Y, Hatori A, Kumata K, Zhang Y, Nengaki N, Kawamura K, Zhang MR.
    • Journal Title

      J Med Chem.

      Volume: 58 Pages: 1513-1523

    • DOI

      10.1021/jm501845n

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Journal Article] Noninvasive quantification of metabotropic glutamate receptor type 1 with [¹¹C]ITDM: a small-animal PET study.2014

    • Author(s)
      Yamasaki T, Fujinaga M, Yui J, Ikoma Y, Hatori A, Xie L, Wakizaka H, Kumata K, Nengaki N, Kawamura K, Zhang MR.
    • Journal Title

      J Cereb Blood Flow Metab.

      Volume: 34 Pages: 606-612

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Journal Article] Comparison of intratumoral FDG and Cu-ATSM distributions in cancer tissue originated spheroid (CTOS xenografts, a tumor model retaining the original tumor properties.2014

    • Author(s)
      Furukawa T, Yuan Q, Jin ZH, Aung W, Yoshii Y, Hasegawa S, Endo H, Inoue M, Zhang MR, Fujibayashi Y, Saga T.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 41 Pages: 653-659

    • DOI

      10.1016/j.nucmedbio.2014.05.139

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591827
  • [Journal Article] PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of 64Cu-cyclam-RAFT-c(-RGDfK-)4 in vivo.2014

    • Author(s)
      Jin ZH, Furukawa T, Sogawa C, Claron M, Aung W, Tsuji AB, Wakizaka H, Zhang MR, Boturyn D, Dumy P, Fujibayashi Y, Saga T.
    • Journal Title

      European Journal of Pharmaceutics and Biopharmaceutics

      Volume: 86(3) Pages: 478-486

    • DOI

      10.1016/j.ejpb.2013.11.006

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591827
  • [Journal Article] Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe 18F-FITM.2014

    • Author(s)
      Xie L, Yui J, Fujinaga M, Hatori A, Yamasaki T, Kumata K, Wakizaka H, Furutsuka K, Takei M, Jin ZH, Furukawa T, Kawamura K, Zhang MR.
    • Journal Title

      Int J Cancer.

      Volume: in press Pages: 1852-1859

    • DOI

      10.1002/ijc.28842

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591827, KAKENHI-PROJECT-24790543, KAKENHI-PROJECT-25293269
  • [Journal Article] Initial human PET studies of metabotropic glutamate receptor type 1 ligand 11C-ITMM2013

    • Author(s)
      Toyohara J., Sakata M., Oda K., Ishii K, Ito K., Hiura M., Fujinaga M., Yamasaki T., Zhang M.R., and Ishiwata K.
    • Journal Title

      J. Nucl. Med.

      Volume: 54(8)(in press) Pages: 1302-1307

    • DOI

      10.2967/jnumed.113.119891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Journal Article] Improvement of brain uptake for in vivo PET imaging of astrocytic oxidative metabolism using benzyl [1-^<11>C]acetate2013

    • Author(s)
      OKADA Maki, NAKAO Ryuji, MOMOSAKI Sotaro, YANAMOTO Kazuhiko, KIKUCHI Tatsuya, OKAMURA Toshimitsu, WAKIZAKA Hidekatsu, HOSOI Rie, ZHANG Ming-Rong, INOUE Osamu.
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 78 Pages: 102-107

    • DOI

      10.1016/j.apradiso.2013.04.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591767
  • [Journal Article] Preclinical and the first clinical studies on [^<11>C]ITMM for mapping metabotropic glutamate receptor type 1 by positron emission tomography.2013

    • Author(s)
      Toyohara J.,Zhang M.-R.
    • Journal Title

      Nucl. Med. Biol.,

      Volume: 40 Pages: 214-220

    • DOI

      10.1016/j.nucmedbio.2012.11.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379, KAKENHI-PROJECT-24390298
  • [Journal Article] ^<18>F-FPIT : A PET Ligand for Imaging of the Metabotropic Glutamate Receptor Type 1 in Rodent and Primate Brains2012

    • Author(s)
      Ming-Rong Zhang, et al
    • Journal Title

      Journal of Neurochemistry

      Volume: 121 Pages: 115-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Journal Article] Imaging for metabotropic glutamate receptor subtype 1 in rat and monkey brains using PET with [18F]FITM2012

    • Author(s)
      Yamasaki T, Fujinaga M, Maeda J, Kawamura K, Yui J, Hatori A, Yoshida Y, Nagai Y, Tokunaga M, Higuchi M, Suhara T, Fukumura T, Zhang MR
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging

      Volume: 39(4) Pages: 632-641

    • DOI

      10.1007/s00259-011-1995-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590053, KAKENHI-PROJECT-22591379
  • [Journal Article] Characterization of 1-(2-[18F] fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo-isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole, a PET ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains2012

    • Author(s)
      Fujinaga M, Maeda J, Yui J, Hatori A, Yamasaki T, Kawamura K, Kumata K, Yoshida Y, Nagai Y, Higuchi M, Suhara T, Fukumura T, Zhang MR
    • Journal Title

      Journal of Neurochemistry

      Volume: 121(1) Pages: 1151-1151

    • DOI

      10.1111/j.1471-4159.2011.07348.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590053, KAKENHI-PROJECT-22591379
  • [Journal Article] Imaging for metabotropic glutamate receptor subtype1 in rat and monkey brains using PET with [^<18>F]FITM2012

    • Author(s)
      Ming-Rong Zhang, et al
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging

      Volume: 39 Pages: 632-641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Journal Article] In vivo measurement of the affinity and density of metabotropic glutamate receptor subtype 1 (mGluR1) in rat brain using [18F]FITM in small-animal PET2012

    • Author(s)
      Yamasaki T,Zhang M.-R
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 53 Pages: 1601-1607

    • DOI

      10.2967/jnumed.112.105908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Journal Article] Development of N-[4-[6-(Isopropylamino)pyrimidin- 4-yl]-1,3-thiazol-2-yl]-N-methyl-4-[11C]methylbenzamide for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor Subtype 1 in Monkey Brain2012

    • Author(s)
      Masayuki Fujinaga
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 55 Pages: 10042-10051

    • DOI

      10.1021/jm301597s

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590053, KAKENHI-PROJECT-22591379
  • [Journal Article] Synthesis and evaluation of novel radioligands for positron emission tomography imaging of metabotropic glutamate receptor subtype 1 (mGluR1) in rodent brain2012

    • Author(s)
      Fujinaga M, Zhang M.-R
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 55 Pages: 2342-2352

    • DOI

      10.1021/jm201590g

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Journal Article] Synthesis and evaluation of 6-[1-(2-[18F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain2011

    • Author(s)
      Fujinaga M, Zhang MR
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 19 Pages: 102-110

    • DOI

      10.1016/j.bmc.2010.11.048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Journal Article] Synthesis and evaluation of 6-[1-(2-[^<18>F]fluoro-3-pyridyl)-5-methyl-lH-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 inbrain2011

    • Author(s)
      Ming-Rong Zhang, et al.
    • Journal Title

      Bioorganic & Medicinal Chemistry.

      Volume: 19 Pages: 102-110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Journal Article] Radiosynthesis and preliminary evaluation of 4-[18F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as a new positron emission tomography ligand for metabotropic glutamate receptor subtype 12011

    • Author(s)
      Yamasaki T, Zhang M.-R
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 21 Pages: 2998-3001

    • DOI

      10.1016/j.bmcl.2011.03.046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Journal Article] Radiosynthesis and evaluation of [^<11>C]YM-202074 as a PET ligand for imaging the metabotropic glutamate receptor type 12010

    • Author(s)
      Ming-Rong Zhang, et al.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 37 Pages: 615-624

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Journal Article] In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [18F]FEDAC.2010

    • Author(s)
      Yanamoto K, Kumata K, Fujinaga M, Nengaki N, Takei M, Wakizaka H, Hosoi R, Momosaki S, Yamasaki T, Yui J, Kawamura K, Hatori A, Inoue O, Zhang MR
    • Journal Title

      Nucl Med Biol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390319
  • [Journal Article] PK11195 might selectively suppress the quinolinic acid-induced enhancement of anaerobic glycolysis in glial cells.2010

    • Author(s)
      Momosaki S, Imamoto N, Hosoi R, Sawada Y, Abe K, Zhang MR, Inoue O
    • Journal Title

      Brain Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390319
  • [Journal Article] In vivo monitoring of extracellular ^<13>N-glutamine derived from blood-borne ^<13>N-ammonia in rat striatum using microdialvsis with radio-LC method.2009

    • Author(s)
      Okada M, Nakao R, Hosoi R, Zhang MR, Fukumura T, Suzuki K, Inoue O.
    • Journal Title

      J Neurosci Methods. 184(1)

      Pages: 37-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390319
  • [Journal Article] Evaluation of N-benzyl-N-[11C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro -9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat2009

    • Author(s)
      Yanamoto K, Yamasaki T, Kumata K., Yui J., Odawara C., Kawamura K., Hatori A., Inoue O., Yamaguchi M., Suzuki K., Zhang M.-R.
    • Journal Title

      Synapse Doi 10.1002/syn.20678

    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] In vivo monitoring of extracellular 13N-glutamine derived from bloodborne 13N-ammonia in rat striatum using microdialysis with radio-LC method.2009

    • Author(s)
      Okada M, Nakao R, Hosoi R, Zhang MR, Fukumura T, Suzuki K, Inoue O
    • Journal Title

      J Neurosci Methods 184(1)

      Pages: 37-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390319
  • [Journal Article] Evaluation of N-benzyl-N-[11C] methyl-2-(7-methyl-8-oxo-2-phenyl-7, 8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.2009

    • Author(s)
      Yanamoto K, Yamasaki T, Kumata K, Yui J, Odawara C, Kawamura K, Hatori A, Inoue O, Yamaguchi M, Suzuki K, Zhang MR
    • Journal Title

      Synapse 63(11)

      Pages: 961-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390319
  • [Journal Article] 18F]FEAC and [18F]FEDAC: two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in brain2009

    • Author(s)
      Yanamoto K., Kumata K., Yamasaki T., Odawara C., Kawamura K., Yui J., Hatori A., Suzuki K., Zhang M.-R
    • Journal Title

      Bioorganic and Medicinal Chemistry Letters 19

      Pages: 1707-1710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] Evaluation of N-benzyl-N-[^<11>C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([^<11>C] DAC as a novel translocator protein (18kDa) radioligand in kainic acid-lesioned rat2009

    • Author(s)
      Ming-Rong Zhang, et al.
    • Journal Title

      Synapse (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] [^<18>F] FEAC and [^<18>F] FEDAC : two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in brain2009

    • Author(s)
      Ming-Rong Zhang, et al.
    • Journal Title

      Bioorganic and Medicinal Chemistry Letters 19

      Pages: 1707-1710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] Evaluation of N-benzyl-N-[^<11>C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([^<11>C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.2009

    • Author(s)
      Yanamoto K, Yamasaki T, Kumata K, Yui J, Odawara C, Kawamura K, Hatori A, Inoue O, Yamaguchi M, Suzuki K, Zhang MR.
    • Journal Title

      Synapse. 63(11)

      Pages: 961-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390319
  • [Journal Article] Astroglial peripheral benzodiazepine receptor as an indicator of neurotrophic support by as trocytes coupled with nontoxic microgliosis2008

    • Author(s)
      Ming-Rong Zhang, et al.
    • Journal Title

      Journal of Neuroscience 28

      Pages: 12255-12267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] Astroglial peripheral benzodiazepine receptor as an indicator of neurotrophic support by astrocytes coupled with nontoxic microgliosis2008

    • Author(s)
      Ji B., Maeda J., Sawada M., Ono M., Okauchi T., Inaji M., Zhang M.-R., Suzuki K., Ando K., Higuchi M., Suhara T
    • Journal Title

      Journal of Neuroscience 28

      Pages: 12255-12267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] [11C]AC-5216: A novel positron emission tomography ligand for peripheral-type benzodiazepine receptors in primate brain2007

    • Author(s)
      .Zhang M.-R., Kumata K., Maeda J., Yanamoto K., Hatori A., Okada M., Higuchi M., Obayashi S., Suhara T., Suzuki K
    • Journal Title

      Journal of Nuclear Medicine 48

      Pages: 1853-1861

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[131I]iodo-5-methoxybenzyl)acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain.2007

    • Author(s)
      Ming-Rong Zhang, et. al.
    • Journal Title

      Journal of Medicinal Chemistry 50

      Pages: 2735-2742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] In vitro and ex vivo autoradiography studies on peripheral-type benzodiazepine receptor binding using [11C]AC-5216 in normal and kainic acid-lesioned rat2007

    • Author(s)
      Yanamoto K., Zhang M.-R., Kumata K., Hatori A., Okada M., Suzuki K
    • Journal Title

      Neuroscience Letters 428

      Pages: 59-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] A practical route for synthesizing a PET ligand containing [18F]fluorobenzene using reaction of diphenyliodonium salt with[18F]F.2007

    • Author(s)
      Ming-Rong Zhang, et. al.
    • Journal Title

      Tetrahedron Letters 48

      Pages: 8632-8635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Journal Article] [11C]AC-5216: A novel positron emission tomography ligand for peripheral-type benzodiazepine receptors in primate brain.2007

    • Author(s)
      Ming-Rong Zhang, et. al.
    • Journal Title

      Journal of Nuclear Medicine 48

      Pages: 1853-1861

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Presentation] 簡易的1ポット[18F]フルオロアルキル化標識法を用いた[18F]フルオロメチルコリンの合成検討2021

    • Author(s)
      河村 和紀, 栗原 雄祐, 小川 政直, 塚越 海渡, 大久保 崇之, 橋本 裕輝, 念垣 信樹, 張 明栄
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03610
  • [Presentation] 11C-L-1MTrp-PETによるメラノーマ免疫化学療法における免疫応答判定2021

    • Author(s)
      謝 琳, Hu Kuan, 熊田 勝志, 脇坂 秀克, 張 一鼎, 念垣 信樹, 下川 卓志, 張 明栄
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07659
  • [Presentation] Radiolabeling agents for development of novel PET tracers for neuroimaging2021

    • Author(s)
      Zhang Ming-Rong
    • Organizer
      The 7th PET/CT-MRI Multimodal Molecular Imaging Summit Forum, The 3rd International symposium on PET Ligand Developmen
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021

    • Author(s)
      Hu Kuan, Xie Lin, Zhang Yiding, Hanyu Masayuki, Zhang Ming-Rong
    • Organizer
      第61回日本核医学会学術総会, 日本核医学会
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Development of a novel PET tracer for imaging of γ-8 dependent transmembrane AMPA receptor regulatory protein2021

    • Author(s)
      Yu Qingzhen, Liang Steven, Zhang Ming-Rong
    • Organizer
      eSRS, Society of Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Development of a stable peptide-based PET tracer for detecting CD133-expressing cancer stem cells2021

    • Author(s)
      Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Obata Honoka , Nagatsu Kotaro , Suzuki Hisashi , Zhang Ming-Rong
    • Organizer
      第4回日本核医学会分科会放射線薬品科学研究会 第20回放射性医薬品・画像診断薬研究会
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021

    • Author(s)
      Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong:
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Presentation] 認知症PETプローブ開発と応用2021

    • Author(s)
      Zhang Ming-Rong
    • Organizer
      17th Nuclear Medicine Academic Conference of Jiangsu Medical Association
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] TRT薬剤「211At-AITM」合成法の改良2021

    • Author(s)
      破入 正行, 峯岸 克行, 門間 あゆみ, 謝 琳, Hu Kuan, 張 一鼎, 藤永 雅之, 永津 弘太郎, 張 明栄
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07659
  • [Presentation] Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-indole Derivatives as Novel Positron-Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain2021

    • Author(s)
      Hattori Yasushi, Tomoteru Yamasaki, Ohashi Tomohiro, Miyanohana Yuhei, Kusumoto Tomokazu, Maeda Ryouta, Miyamoto Maki, Debori Yasuyuki, Hata Akiko, Zhang Yiding, Wakizaka Hidekatsu, Wakabayashi Takeshi, Fujinaga Masayuki, Yamashita Ryo, Zhang Ming-Rong, Koike Tatsuki
    • Organizer
      AIMECS 2021, Asian Federation for Medicinal Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Whole-body PET Tracking of a D-dodecapeptide and its Radiotheranostic Potential for PD-L1 overexpressed tumors2021

    • Author(s)
      Hu Kuan, Xie Lin, Zhang Yiding, Hanyu Masayuki, Zhang Ming-Rong
    • Organizer
      SNMMI2021, Society of Nuclear Medicine and Molecular Imaging
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] PEGylation modulation of peptides promotes PET detection of cancers2021

    • Author(s)
      Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong
    • Organizer
      eSRS
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021

    • Author(s)
      Hu Kuan, Xie Lin, Yiding Zhang, Hanyu Masayuki, Zhang Ming-Rong
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07659
  • [Presentation] PETプローブの開発と臨床応用2021

    • Author(s)
      張 明栄
    • Organizer
      順天堂大学大学院医学研究科循環器内科 循環器セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] PET imaging of PD-L1 overexpressing tumors with a 68Ga labeled D-dodecapeptide2021

    • Author(s)
      Hu Kuan, Xie Lin, Hanyu Masayuki, Zhang Yiding, Zhang Ming-Rong
    • Organizer
      eSRS, Society of Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Development and Production of Radiopharmaceuticals in National Institutes for Quantum and Radiological Science and Technology (QST)2021

    • Author(s)
      Zhang Ming-Rong
    • Organizer
      PETセミナー in Yale University
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Synthesis, Radiolabeling and Biological Evaluation of a Novel Trace Amine-Associated Receptor 1 (TAAR1) PET radioligand2021

    • Author(s)
      Haider Ahmed, Sun Jiyun, Chen Jiahui, Rong Jian, Shao Tuo, Wang Lu, Xu Hao, Zhang Ming-Rong, Liang Steven
    • Organizer
      eSRS, Society of Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] In vivo PET imaging of cancer α5β1-integrin using a pegylated peptide2021

    • Author(s)
      Hu Kuan , 謝 琳 , 張 一鼎 , 破入 正行 , 張 明栄:
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02873
  • [Presentation] PET imaging of PD-L1 overexpressing tumors with a 68Ga labeled D-dodecapeptide2021

    • Author(s)
      Hu Kuan, Xie Lin, Hanyu Masayuki, Yiding Zhang, Zhang Ming-Rong
    • Organizer
      eSRS, Society of Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07659
  • [Presentation] A platform of Radiopharmaceutical Development for Positron Emission Tomography Imaging and Targeted Radionuclide Therapy Studies2020

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      The International Forum on Innovative Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] 脳内NMDA受容体を標的としたPET薬剤の合成と評価2020

    • Author(s)
      熊田 勝志, 張 一鼎, 山崎 友照, 念垣 信樹, 張 明栄
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Preclinical evaluation of radiolabeled negative allosteric modulators for PET imaging of metabotropic glutamate receptor 22020

    • Author(s)
      Wang Lu, Xiaofei Zhang, Zhen Chen, Hao Xu, Yihan Shao, Douglas Sheffler, Ming-Rong Zhang, Steven H. Liang
    • Organizer
      SNMMI 2020 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] [11C]SL25.1188の臨床提供に向けた安定的製造法及び品質検査法の確立2020

    • Author(s)
      河村和紀、橋本裕輝、大久保崇之、古塚賢士、藤代智也、富樫隆啓、武藤正敏、森若菜、小川政直、念垣信樹、張明栄
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03610
  • [Presentation] グルタミン酸受容体サブタイプ特異的なPETプローブの開発2020

    • Author(s)
      張 明栄
    • Organizer
      第60回日本核医学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Synthesis and preclinical evaluation of 11C-labeled (6-aryl-1H-pyrrolo[3,2-b]pyridin-1-yl)acetamide for imaging GluN2B subunit of NMDA receptors2020

    • Author(s)
      Jiyun Sun, Zhen Chen, Jiahui Chen, Hualong Fu, Tuo Shao, Wang Lu, Hao Xu, Ming-Rong Zhang, Steven H. Liang
    • Organizer
      SNMMI 2020 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] 脳内D-アミノ酸オキシダーゼの新規PETプローブ[11C]DAO-1903の合成と評価2020

    • Author(s)
      張 一鼎, 熊田 勝志, 小川 政直, 栗原 雄祐, 念垣 信樹, 張 明栄
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03635
  • [Presentation] Radiosynthesis and evaluation of a negative allosteric modulator for the PET imaging of metabotropic glutamate receptor 2 in rat brain2019

    • Author(s)
      Kumata K, Zhang Y, Hatori A, Yamasaki T, Kurihara Y, Nengaki N, Zhang MR
    • Organizer
      The 23nd International symposium on radiopharmaceutical science (ISRS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Small-animal PET study: excess glutamate release upregulates mGluR1 availability2019

    • Author(s)
      山崎友照, 岡田真希, 森若菜, 張一鼎, 脇坂秀克, 小川政直, 藤永雅之, 張明栄
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Radiosynthesis of [18F]FEDAC with the hydrous 18F-fluorination using Kryptofix 222 and potassium carbonate2019

    • Author(s)
      Kawamura K, Kumata K, Mori W, Fujinaga M, Kurihara Y, Ogawa M, Nengaki N, Zhang MR.
    • Organizer
      International Symposium on Radiopharmaceutical Sciences 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03610
  • [Presentation] Development of PET Tracers for Imaging of Neuroinflammation and Dementia2019

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      The 2nd International symposium on PET Ligand Development and Molecular Imaging
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] [11C]で標識したMAGLに選択的な新規PETリガンドの合成及び動物評価2019

    • Author(s)
      森 若菜, 栗原 雄祐, 羽鳥 晶子, 張 一鼎, 藤永 雅之, 張 明栄
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10461
  • [Presentation] Synthesis and evaluation of a new PET ligand for imaging of monoacylglycerol lipase in brain2019

    • Author(s)
      Mori W, Kurihara Y, Hatori A, Zhang Y, Fujinaga M, Zhang MR
    • Organizer
      The 23nd International symposium on radiopharmaceutical science (ISRS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Monoacylglycerol lipaseのPETプローブ[18F]PF06795071の評価2019

    • Author(s)
      羽鳥 晶子、森 若菜、張 一鼎、藤永 雅之、張 明栄
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10461
  • [Presentation] Development of PET tracers for neuroinflammation in Alzheimer’s disease2019

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      World Molecular Imaging Congress 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Development of Radiopharmaceuticals for PET Imaging and Targeted Radionuclide Therapy2019

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      The 15th Hangzhou International Molecular Imaging Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Development of scandium-catalyzed N-[18F]fluoroalkylation of aryl and heteroaryl amines with [18F]epifluorohydrin2019

    • Author(s)
      Fujinaga M, Ohkubo T, Kumata K, Nengaki N, Zhang MR
    • Organizer
      The 23nd International symposium on radiopharmaceutical science (ISRS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Visualization of MAGL in ischemia rat brain using PET probe 11C-SAR1273032019

    • Author(s)
      Akiko Hatori, Yiding Zhang, Wakana Mori, Yusuke Kurihara, Hidekatsu Wakisaka, Ming-Rong Zhang
    • Organizer
      Brain & Brain PET 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10461
  • [Presentation] 代謝型グルタミン酸受容体2に選択的な新規[11C]標識PETリガンドの合成と評価2019

    • Author(s)
      熊田勝志, 山崎友照, 張一鼎, 森若菜, 藤永雅之, 羽鳥晶子, 念垣信樹, 張明栄
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] 1つの反応容器を用いた[18F]フルオロエチル化合成法の確立―[18F]FEDAC及び[18F]FET合成について2019

    • Author(s)
      河村和紀、熊田勝志、森若菜、藤永雅之、栗原雄祐、小川政直、大久保崇之、念垣信樹、張明栄
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03610
  • [Presentation] 211-At-Labeled Radiotracers: Synthesis and Preclinical Evaluation2019

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      The 14th International Conference on the Radiopharmaceutical Therapy (ICRT)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Preclinical PET imaging of inflammation in peripheral system with radioligands for translocator protein (18 kDa)2019

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      The 13th Asia Oceania of Nuclear Medicine and Biology (AOCNMB2019)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] 脳虚血モデルラットを用いたPETプローブ[11C]SAR1による脳内MAGLの画像化2018

    • Author(s)
      羽鳥 晶子、張 一鼎、森 若菜、栗原 雄祐、脇坂 秀克、張 明栄
    • Organizer
      日本核医学会
    • Data Source
      KAKENHI-PROJECT-17K10461
  • [Presentation] Development and Application of radiotracers for Metabotropic Glutamate Receptor Subtype 1: from PET Imaging to Targeted Radionuclide Therapy2018

    • Author(s)
      張 明栄
    • Organizer
      The 3rd China-America Nuclear Medicine Academic Forum
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Development and radiotherapeutic effect of two novel I-131 or At-211 labelled radioprobes for melanoma with overexpressed metabotropic glutamate receptor 12018

    • Author(s)
      Masayuki Hanyu, Lin Xie, Masayuki Fujinaga, Yiding Zhang, Akiko Hatori, Yukie Morokoshi, Huizi Li, Katsuyuki Minegishi, Sumitaka Hasegawa, Kotaro Nagatsu, Ming-Rong Zhang
    • Organizer
      12th Congress of the World federation of Nuclear Medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] 18F-FEDAC Translocator Protein PET/CT for the early detection of mitochondria dysfunction secondary to myocardial ischemia2018

    • Author(s)
      Rui Luo, Feng WANG, Ming-Rong Zhang
    • Organizer
      SNMMI 2018 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] In vivo characterizations of [11C]BMS193885 and [11C]Desmethyl-BMS193885 as a PET tracer for neuropeptide Y Y1 receptors2018

    • Author(s)
      Kazunori Kawamura , Wakana Mori , Tomoteru Yamasaki , Yiding Zhang , Masayuki Fujinaga , Akiko Hatori , Lin Xie , Katsushi Kumata , Takayuki Ohkubo , Yusuke Kurihara , Masanao Ogawa , Nobuki Nengaki , Ming-Rong Zhang
    • Organizer
      12th World Congress of the World Federation of Nuclear medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] 代謝型グルタミン酸受容体2に選択的な新規11C-標識PETリガンドの合成と評価2018

    • Author(s)
      熊田勝志、山崎友照、張一鼎、森若菜、羽鳥晶子、藤永雅之、念垣信樹、張明栄
    • Organizer
      第58回日本核医学会総会
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Practical radiolabelling techniques with 18F for development of PET radiotracers for clinical use2018

    • Author(s)
      張 明栄
    • Organizer
      第58回日本核医学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Development of Radiolabeling Techniques and Clinically Useful PET Tracers for Neuroimaging2018

    • Author(s)
      張 明栄
    • Organizer
      The 1st International Symposium on PET Ligand Development and Molecular NeuroImaging & The 5th PET
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] PD-L1をターゲットするPET診断及びがん免疫治療用の新規標識ペプチドの開発研究2018

    • Author(s)
      Hu Kuan, 謝 琳, 破入 正行, 張 明栄
    • Organizer
      第2回日本核医学会分科会 放射性薬品科学研究会 第18回放射性医薬品・画像診断薬研究会
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Development of Useful Radioprobes for Targeted Radionuclide Therapy and PET Imgaing Studies2018

    • Author(s)
      張 明栄
    • Organizer
      The 4th International Symposium on Molecular Imaging and Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Development of [11C]CMDC for PET imaging of metabotropic glutamate receptor 2 in the rat brain2017

    • Author(s)
      Katsushi Kumata, Yiding Zhang, Akiko Hatori, Tomoteru Yamasaki, Takayuki Ohkubo, Yusuke Kurihara, Masayuki Fujinaga, Lin Xie, Kazunori Kawamura, Ming-Rong Zhang
    • Organizer
      22nd International symposium on radiopharmaceutical science (ISRS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Synthesis and evaluation of a new 11C-labeled growth hormone secretagogue receptor 1a probe2017

    • Author(s)
      Kazunori Kawamura , Masayuki Fujinaga , Yoko Shimoda , Tomoteru Yamasaki , Yiding Zhang , Akiko Hatori , Lin Xie , Hidekatsu Wakizaka , Yusuke Kurihara , Takayuki Ohkubo , Masanao Ogawa , Nobuki Nengaki , Ming-Rong Zhang
    • Organizer
      22nd International symposium on radiopharmaceutical science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Brain PET study using [11C]BU99008 in Zucker fatty versus lean rats.2017

    • Author(s)
      Kazunori Kawamura , Tomoteru Yamasaki , Yiding Zhang , Hidekatsu Wakizaka , Akiko Hatori , Lin Xie , Masayuki Fujinaga , Ming-Rong Zhang
    • Organizer
      2017 World Molecular Imaging Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] 新規GHS-R1a選択的PET用プローブの開発と評価2017

    • Author(s)
      河村 和紀 , 藤永 雅之 , 下田 陽子 , 山崎 友照 , 張 一鼎 , 羽鳥 晶子 , 謝 琳 , 脇坂 秀克 , 栗原 雄祐 , 大久保 崇之 , 小川 政直 , 念垣 信樹 , 張 明栄
    • Organizer
      第57回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Development of New Radiolabeling Techniques and Useful Radioprobes for Clinical Study2017

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      分子イメージング厦門国際学会2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Synthesis and evaluation of radionuclide therapy probe for metabotropic glutamate receptor 1 in melanoma2017

    • Author(s)
      Masayuki Fujinaga, Lin Xie, Yiding Zhang, Masayuki Hanyu, Tomoteru Yamasaki, Akiko Hatori, Katsushi Kumata, Ming-Rong Zhang
    • Organizer
      22th International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      International Congress Center Dresden, Dresden, Germany
    • Year and Date
      2017-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Synthesis and radiotherapeutic effect of two I-131 or At-211 labelled radioprobes for melanoma with overexpressed metabotropic glutamate receptor 12017

    • Author(s)
      Masayuki Hanyu, Masayuki Fujinaga, Lin Xie, Yiding Zhang, Akiko Hatori, Katsuyuki Minegishi, Kotaro Nagatsu, Ming-Rong Zhang
    • Organizer
      10th International Symposium on Targeted Alpha Therapy
    • Place of Presentation
      石川県金沢市昭和町石川県立音楽堂
    • Year and Date
      2017-05-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] 新規代謝型グルタミン酸2型受容体選択的PETリガンドの合成と評価2017

    • Author(s)
      熊田勝志, 山崎友照, 張一鼎, 羽鳥 晶子, 藤永 雅之, 念垣 信樹, 張 明栄
    • Organizer
      第57回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] Development of new radioprobes for PET imaging of metabotropic glutamate receptor subtype 2 in rat brain2017

    • Author(s)
      Katsushi Kumata, Tomoteru Yamasaki, Yiding Zhang, Akiko Hatori, Wakana Mori, Masayuki Fujinaga, Ming-Rong Zhang
    • Organizer
      SNMMI 2017Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04267
  • [Presentation] 肥満ラットでの脳PET定量測定によるイミダゾリンI2受容体及びセロトニントランポーター結合の増加2016

    • Author(s)
      河村 和紀, 下田 陽子, 山崎 友照, 由井 譲二, 張 一鼎, 脇坂 秀克, 羽鳥 晶子, 謝 琳, 武井 誠, 張 明栄
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2016-11-05
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] 腫瘍に発現する代謝型グルタミン酸受容体1型を標的とする内用療法放射性プローブの開発2016

    • Author(s)
      藤永雅之、謝琳、張一鼎、山崎友照、羽鳥晶子、熊田勝志、張明栄
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      愛知県名古屋市熱田区名古屋国際会議場
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Development of Radioprobes for Imaging of Metabotrophic Glutamate I Receptor and Treatment of Cancer2016

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      Advanced Medical Systems社
    • Place of Presentation
      Nanjing, China
    • Year and Date
      2016-03-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Changes of metabotropic glutamate receptor type 1 binding of [11C]ITMM by aging.2015

    • Author(s)
      Sakata M., Toyohara J., Wagatsuma K., Ishibashi K., Ishii K., Zhang M-R., Ishiwata K.
    • Organizer
      12th International Conference on Quantification of Brain Function with PET (BrainPET 2015)
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2015-06-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] PET imaging of a feeding center using [11C]BU99008 with ultra-high specific activity2015

    • Author(s)
      Kazunori Kawamura, Yoko Shimoda, Joji Yui, Yiding Zhang, Tomoteru Yamasaki, Hidekatsu Wakizaka, Masayuki Fujinaga, Katsushi Kumata, Lin Xie, Akiko Hatori, Masanao Ogawa, Yusuke Kurihara, Nobuki Nengaki, Ming-Rong Zhang.
    • Organizer
      Annual Congress of the European Association of Nuclear Medicine 2015
    • Place of Presentation
      Congress Center Hamburg, Hamburg, Germany
    • Year and Date
      2015-10-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] イミダゾリンI2受容体選択的PET用リガンド[11C]BU99008の超高比放射能化による有用性検討2015

    • Author(s)
      河村 和紀 , 下田 陽子 , 由井 譲二 , 張 一鼎 , 山崎 友照 , 脇坂 秀克 , 藤永 雅之 , 熊田 勝志 , 小川 政直 , 張 明栄
    • Organizer
      第55回日本核医学会学術総会
    • Place of Presentation
      ハイアットリージェンシー東京、東京都
    • Year and Date
      2015-11-05
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] [11C]ITMMによる代謝型グルタミン酸受容体1結合能の加齢変化2015

    • Author(s)
      坂田宗之、豊原潤、我妻慧、石橋賢士、石井賢二、張明栄、石渡喜一
    • Organizer
      第55回日本核医学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-05
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] Radiosynthesis and evaluation of [11C]BU99008 with ultra-high specific activity as a PET ligand for imaging I2-imidazoline receptors.2015

    • Author(s)
      Kazunori Kawamura , Yoko Shimoda , Joji Yui , Masayuki Fujinaga , Tomoteru Yamasaki , Akiko Hatori , Lin Xie , Yiding Zhang , Katsushi Kumata , Masanao Ogawa , Kurihara Yusuke , Nobuki Nengaki , Hidekatsu Wakizaka , Ming-Rong Zhang.
    • Organizer
      21st International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      University of Missouri, Columbia, MO, USA
    • Year and Date
      2015-05-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] 代謝型グルタミン酸受容体タイプ1の加齢変化&#8212;[11C]ITMM-PETを用いた検討2015

    • Author(s)
      坂田宗之、豊原潤、我妻慧、石橋賢士、石井賢二、張明栄、石渡喜一
    • Organizer
      第38回基礎老化学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2015-06-13
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] Development of 11C-IITM for imaging of metabotropic glutamate 1 receptor in melanoma2015

    • Author(s)
      Lin Xie, Masayuki Fujinaga, Tomoteru Yamasaki, Joji Yui, Akiko Hatori, Yiding Zhang, Nobuki Nengaki, Kazunori Kawamura, Ming-Rong Zhang
    • Organizer
      SNMMI 2015 Annual Meeting
    • Place of Presentation
      Baltimore, Maryland.USA
    • Year and Date
      2015-06-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] 分子プローブの開発と医薬品開発への応用2015

    • Author(s)
      張 明栄
    • Organizer
      南京医科大学第一附属病院
    • Place of Presentation
      Nanjing, China
    • Year and Date
      2015-10-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] メラノーマに過剰発現するmGlu1を標的とする[18F]FITM-PETイメージング2013

    • Author(s)
      謝琳、由井譲二、藤永雅之、羽鳥晶子、山崎友照、熊田勝志、脇坂秀克、念垣信樹、河村和紀、張明栄
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] First imaging of metabotropic glutamate 1 receptor in melanoma with a positron emission tomography probe 18F-FITM2013

    • Author(s)
      Lin Xie, Joji Yui, Masayuki Fujinaga, Akiko Hatori, Tomoteru Yamasaki, Hidekatsu Wakizaka, Kazunori Kawamura, Ming-Rong Zhang
    • Organizer
      SNMMI 2013 Annual Meeting
    • Place of Presentation
      カナダ、バンクーバー
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Initial evaluation of [11C]ITMM for mapping metabotropic glutamate receptor type 1 in human brain.2013

    • Author(s)
      Sakata, M., Toyohara, J., Oda, K., Ishii, K. Zhang, MR., Ishiwata, K.
    • Organizer
      11th International Conference on Quantification of Brain Function with PET (BrainPET ’13)
    • Place of Presentation
      Syanghai
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] 代謝型グルタミン酸受容体タイプ1リガンド[11C]ITMMのヒト脳PET計測2013

    • Author(s)
      坂田宗之、豊原潤、織田圭一、石井賢二、張明栄、石渡喜一
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] メラノーマに過剰発現する代謝型グルタミン酸1型受容体を標的とする[18F]FITM-PETイメージング2013

    • Author(s)
      謝琳、由井譲二、藤永雅之、羽鳥晶子、山崎友照、張明栄
    • Organizer
      第13回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] [^<14>C]Benzyl Acetateの脳内動態の測定とその解析2012

    • Author(s)
      香川智彦、吉野恵子、柳本和彦、細井理恵、木村敦臣、井上修、岡田真希、張明栄
    • Organizer
      第12回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-23591767
  • [Presentation] 代謝型グルタミン酸受容体サブタイプ1リガンド^<11>C-ITMMの非臨床研究2012

    • Author(s)
      豊原潤、坂田宗之、ジェッケルクリスチナ、藤永雅之、張明栄、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] 代謝調節型グルタメート受容体サブタイプ1型のPETイメージング剤の開発と応用2012

    • Author(s)
      張 明栄
    • Organizer
      IBICセミナー
    • Place of Presentation
      国立精神医療センター
    • Year and Date
      2012-11-21
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] 代謝型グルタミン酸受容体サブタイプ1 (mGluRl)リガンド^<11>C-ITMMの初期臨床評価2012

    • Author(s)
      豊原潤、坂田宗之、伊藤公輝、日浦幹夫、織田圭一、石井賢二、張明栄、石渡喜一
    • Organizer
      第12回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] Development of Two PET probes [18F]FPTQ and [18F]FPIT for imaging of metabotropic glutamate receptor 1 (mGluR1)in brain2011

    • Author(s)
      張 明栄
    • Organizer
      中国腫瘍及び核医学分子標的診断シンポジウム
    • Place of Presentation
      南京医科大学、中国
    • Year and Date
      2011-05-09
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] 短寿命放射性合成中間体の製造とPETプローブ開発への応用2011

    • Author(s)
      張 明栄
    • Organizer
      第4回岡山大&理研ジョイントシンポジウム -先端計測技術と分析化学イノベーション
    • Place of Presentation
      岡山大学
    • Year and Date
      2011-07-02
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] Recent advance in development of positron emission tomography probes for brain and tumor imaging2011

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      2011' National Forum of Tumor Marker and Molecular Targeted Diagnosis & Treatment by Nuclear medicine
    • Place of Presentation
      中国、南京
    • Year and Date
      2011-05-10
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] Development of Radiolabeling Technique for PET Probe2011

    • Author(s)
      張 明栄
    • Organizer
      ワークショップ&放医研-北大教育プログラムに本ワークショップ
    • Place of Presentation
      北海道大学
    • Year and Date
      2011-07-28
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] Development and production of radiopharmaceuticals in National Institute of Radiological Sciences (NIRS)2010

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      Eighth China-Japan joint seminar on radiop harmaceutical Chemistry
    • Place of Presentation
      Beijing, China
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] Development and production of radiopharmaceuticals in National Institute of Radiological Sciences (NIRS)2010

    • Author(s)
      張 明栄
    • Organizer
      Eighth China-Japan Joint Seminar on Radiopharmaceutical Chemistry
    • Place of Presentation
      北京師範大学、中国
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] Development of PET probes for metabotropic glutamate recepfor type 1 in brain2010

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      Seminar of Nanjing Medicinal University
    • Place of Presentation
      Nanjing, China
    • Year and Date
      2010-10-25
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] New ^18F-Radiochemistry and Application for Development of PET Imaging Agents、2nd Research Coordination Meeting on Development of ^18F-labelled Radiopharmaceuticals (beyond [^18F]FDG) for Use in Oncology and Neurosciences2010

    • Author(s)
      張 明栄
    • Organizer
      国際原子力機構
    • Place of Presentation
      ウイーン、オーストリア
    • Year and Date
      2010-10-04
    • Data Source
      KAKENHI-PROJECT-22591379
  • [Presentation] In vivoマイクロダイアリシスradio-LCを用いたラット線条体細胞外液中13N-アンモニアの動態計測2009

    • Author(s)
      岡田真希, 中尾隆士, 細井理恵, 張明栄, 入江俊章, 福村利光, 鈴木和年, 井上修
    • Organizer
      第49回日本核医学会総会
    • Place of Presentation
      旭川
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-19390319
  • [Presentation] ONE-POT RADIOSYNTHESIS OF [13N]UREA AND [13N]CARBAMATE USING NO-CARRIER-ADDED [13N]NH32008

    • Author(s)
      Zhang M.-R., Kumata K., Ogawa M., Kato K., Suzuki K
    • Organizer
      7^<th> International Conference of Nuclear and Radiochemistry
    • Place of Presentation
      ブタペスト、ハンガリー
    • Year and Date
      2008-08-24
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Presentation] ONE-POT RADIOSYNTHESIS OF [^<13>N] UREA AND [^<13>N] CARBAMATE USING NO-CARRIER-ADDED [^<13>N] NH_32008

    • Author(s)
      Ming-Rong Zhang, et al.
    • Organizer
      7^h International Conference of Nuclear and Radiochemistry
    • Place of Presentation
      ブタペスト、ハンガリー
    • Year and Date
      2008-08-24
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Presentation] [11C]AC-5216: RADIOSYNTHESIS AND EVALUATION AS A NOVEL PET LIGAND FOR THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR IN BRAIN2007

    • Author(s)
      Zhang M.-R., K. Kumata, J. Maeda, K. Yanamoto, M. Amitani, J. Noguchi, T. Okauchi, T. Suhara, K. Suzuki
    • Organizer
      7^<th> International Symposium on Radiopharmaceutical
    • Place of Presentation
      アーヘン、ドイツ
    • Year and Date
      2007-04-30
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Presentation] [11C]AC-5216:RADIOSYNTHESIS AND EVALUATION AS A NOVEL POSITRON EMISSION TOMOGRAP HY LIGAND FOR PERIPHERAL-TYPE BENZODIAZEPINE RECEPTORS IN PRIMATE BRAIN.2007

    • Author(s)
      Ming-Rong Zhang, et. al.
    • Organizer
      17th International symposium on radiopharmaceutical sciences
    • Place of Presentation
      アーヘン、ドイツ
    • Year and Date
      2007-04-30
    • Data Source
      KAKENHI-PROJECT-19590114
  • [Presentation] Labeling and stability studies for a tetrameric cyclic RGD peptide based radiopharmaceutical 64/67Cu-cyclam-RAFT-c(-RGDfK-)4

    • Author(s)
      Zhao-Hui Jin, Takako Furukawa, Mélissa Degardin, Didier Boturyn, Ming-Rong Zhang, Yasuhisa Fujibayashi, Pascal Dumy, Tsuneo Saga
    • Organizer
      2015 World Molecular Imaging Congress
    • Place of Presentation
      Honolulu, Hawaii
    • Year and Date
      2015-09-02 – 2015-09-05
    • Data Source
      KAKENHI-PROJECT-24591827
  • [Presentation] 腫瘍に発現する代謝型グルタミン酸受容体1をターゲットとするPETプローブの開発

    • Author(s)
      藤永雅之、謝 琳、山崎友照、由井譲二、熊田勝志、下田陽子、羽鳥晶子、念垣信樹、張明栄
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Development of 18F-labeled fibronectin-mimetic peptide for positron emission tomography imaging of a5b1 integrin expression

    • Author(s)
      Zhao-Hui Jin, Takako Furukawa, Katsushi Kumata, Lin Xie, Joji Yui, Hidekatsu Wakizaka, Yasuhisa Fujibayashi, Ming-Rong Zhang, Tsuneo
    • Organizer
      2014 World Molecular Imaging Congress
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-09-17 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-24591827
  • [Presentation] イミダゾリンI2受容体イメージング用18F標識PET用プローブの開発

    • Author(s)
      河村和紀、下田陽子、山﨑友照、由井譲二、熊田勝志、藤永雅之、謝琳、羽鳥晶子、脇坂秀克、小川政直、張明栄
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪府立国際会議場(大阪)
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] [14C]Benzyl Acetate の脳内動態の測定とその解析

    • Author(s)
      香川智彦、吉野恵子、柳本和彦、細井理恵、木村敦臣、井上 修、岡田真希、張 明栄
    • Organizer
      第12回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-23591767
  • [Presentation] Oncoimaging of melanoma by targeted ectopic metabotropic glutamate 1 receptor with a positron emission tomography radioprobe 18F-FITM

    • Author(s)
      Lin Xie, Joji Yui, Masayuki Fujinaga, Akiko Hatori, Tomoteru Yamasaki, Katsushi Kumata, Hidekatsu Wakizaka, Kazunori Kawamura, Ming-Rong Zhang
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Identifying neuronal damage and neuroprotective effects in vivo by 11C-ITMM PET imaging

    • Author(s)
      Lin Xie, Joji Yui, Masayuki Fujinaga, Tomoteru Yamasaki, Akiko Hatori, Katsushi Kumata,Nobuki Nengaki, Ming-Rong Zhang
    • Organizer
      日中核医学交流合同シンポジウム in 沖縄
    • Place of Presentation
      メルキュールホテル沖縄那覇(沖縄県那覇市)
    • Year and Date
      2015-03-14 – 2015-03-15
    • Data Source
      KAKENHI-PROJECT-25293269
  • [Presentation] Synthesis and evaluation of 18F-labeled imidazoline I2 receptor ligand as a PET probe

    • Author(s)
      Kawamura K, Yamasaki T, Shimoda Y, Kumata K, Fujinaga M, Yui J, Xie L, Hatori A, Wakizaka H, Kurihara Y, Ogawa M, Nengaki N, Zhang MR
    • Organizer
      27th Annual Congress of the European Association of Nuclear Medicine
    • Place of Presentation
      Gothenburg, Sweden
    • Year and Date
      2014-10-18 – 2014-10-22
    • Data Source
      KAKENHI-PROJECT-26293283
  • [Presentation] Development of Radioprobes for Imaging of Metabotrophic Glutamate I Receptor and Radionuclide Therapy in Tumor

    • Author(s)
      Ming-Rong Zhang
    • Organizer
      2015 Asia-Pacific Conference of Tumor Biology and Medicine/The 10th China, Nanjing Conference of Molecular Biomarkers and Nuclear Medicine Targeted Theranostics
    • Place of Presentation
      Nanjing, CHINA
    • Year and Date
      2015-03-18 – 2015-03-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293269
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    # of Collaborated Products: 62 results
  • 2.  藤永 雅之 (70623726)
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    # of Collaborated Products: 67 results
  • 3.  山崎 友照 (80627563)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 58 results
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    # of Collaborated Projects: 5 results
    # of Collaborated Products: 30 results
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    # of Collaborated Products: 10 results
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    # of Collaborated Products: 10 results
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    # of Collaborated Products: 3 results
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    # of Collaborated Products: 5 results
  • 19.  ISHIWATA Kiichi (50143037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 20.  MISHINA Masahiro (70322518)
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