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Naoi Yasuto  直居 靖人

ORCIDConnect your ORCID iD *help
Researcher Number 30646211
Other IDs
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 教授
2025: 大阪大学, 大学院医学系研究科, 招へい教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 教授
2022 – 2023: 大阪大学, 大学院医学系研究科, 招へい教授
2021: 大阪大学, 医学系研究科, 招へい教授
2020: 大阪大学, 医学系研究科, 准教授
2016 – 2018: 大阪大学, 医学系研究科, 助教
2013 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
General surgery / Basic Section 55010:General surgery and pediatric surgery-related
Except Principal Investigator
Basic Section 10030:Clinical psychology-related / Basic Section 52040:Radiological sciences-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / General surgery
Keywords
Principal Investigator
マイクロアレイ / 乳癌 / 網羅的遺伝子発現解析 / 多重遺伝子診断法 / 多遺伝子診断法 / Curebest 95GC / RNA sequence / RNA / FFPE / 多遺伝子アッセイ … More / 再発予測 / 転移予測 / 腋窩リンパ節 / 腋窩リンパ節転移 / 多重遺伝子診断 … More
Except Principal Investigator
乳癌 / 高齢者 / 治療選択 / 意思決定 / well-being / 病理学的完全奏功 / 術前化学療法 / pCR / Neoadjuvant chemotherapy / Radiogenomics / MRI / Breast cancer / 質量分析イメージング / TGF-β / 抗HER2抗体 / HER2陽性乳癌 / trastuzumab / TGFβ / 癌幹細胞 / ラパチニブ / トラスツズマブ / SMAD3 / TGF-beta / HER2 Less
  • Research Projects

    (7 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (12 People)
  •  Comprehensive examination of factors related to well-being on medical decision-making

    • Principal Investigator
      加藤 佑佳
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 10030:Clinical psychology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Investigating the heterogeneity and drug sensitivity of breast cancer based on mass spectrometry imaging

    • Principal Investigator
      加藤 千翔
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Construction of Radiogenomics Prediction Model for Pathological Complete Response after Preoperative Chemotherapy for Breast Cancer

    • Principal Investigator
      徳田 由紀子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Osaka University
  •  RNAseq analysis for Curebest 95GCPrincipal Investigator

    • Principal Investigator
      Naoi Yasuto
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Osaka University
  •  Development of recurrence risk prediction model 95-gene classifier and its application to formalin-fixed paraffin-embedded tissues.Principal Investigator

    • Principal Investigator
      Naoi Yasuto
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  Involvement of TGF-beta/SMAD signaling in trastuzumab resistance

    • Principal Investigator
      Shimoda Masafumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  Development of a prediction model for lymph node metastasis in luminal A subtype breast cancerPrincipal Investigator

    • Principal Investigator
      Naoi Yasuto
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University

All 2023 2022 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] Validation of the prognosis of patients with ER-positive, HER2-negative and node-negative invasive breast cancer classified as low risk by Curebest 95GC Breast in a multi-institutional registry study2023

    • Author(s)
      Naoi Yasuto、Tsunashima Ryo、Shimazu Kenzo、Oikawa Masahiro、Imanishi Seiichi、Koyama Hiroshi、Kamada Yoshihiko、Ishihara Kazuhiro、Suzuki Masahiko、Osako Tomo、Kinoshita Takayuki、Suto Akihiko、Nakamura Seigo、Tsuda Hitoshi、Noguchi Shinzaburo
    • Journal Title

      Oncology Letters

      Volume: 25 Issue: 5 Pages: 209-209

    • DOI

      10.3892/ol.2023.13794

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09075, KAKENHI-PROJECT-20K08926
  • [Journal Article] Curebest 95GC -日本で開発された多遺伝子発現解析-2017

    • Author(s)
      直居 靖人
    • Journal Title

      Current Therapy

      Volume: Vol.35, No.9

    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Journal Article] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Journal Title

      日本臨床

      Volume: 75巻 増刊号3

    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Journal Article] Development of a prediction model for lymph node metastasis in luminal A subtype breast cancer: the possibility to omit sentinel lymph node biopsy.2014

    • Author(s)
      Nakauchi C, Naoi Y, Shimazu K, Tsunashima R, Nishio M, Maruyama N, Shimomura A, Kagara N, Shimoda M, Kim SJ, Noguchi S.
    • Journal Title

      Cancer Lett.

      Volume: Oct 10;353(1) Issue: 1 Pages: 52-8

    • DOI

      10.1016/j.canlet.2014.07.003

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461981
  • [Journal Article] 72-gene classifier for predicting prognosis of estrogen receptor-positive and node-negative breast cancer patients using formalin-fixed, paraffin-embedded tumor tissues.2014

    • Author(s)
      Nishio M, Naoi Y, Tsunashima R, Nakauchi C, Kagara N, Shimoda M, Shimomura A, Maruyama N, Shimazu K, Kim SJ, Noguchi S.
    • Journal Title

      Clin Breast Cancer

      Volume: Jun;14(3) Issue: 3 Pages: e73-e80

    • DOI

      10.1016/j.clbc.2013.11.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461981
  • [Journal Article] Construction of novel immune-related signature for prediction of pathological complete response to neoadjuvant chemotherapy in human breast cancer.2014

    • Author(s)
      Sota Y, Naoi Y, Tsunashima R, Kagara N, Shimazu K, Maruyama N, Shimomura A, Shimoda M, Kishi K, Baba Y, Kim SJ, Noguchi S.
    • Journal Title

      Ann Oncol.

      Volume: Jan;25(1) Issue: 1 Pages: 100-6

    • DOI

      10.1093/annonc/mdt427

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461981
  • [Presentation] 閉経期乳癌の治療2023

    • Author(s)
      直居 靖人
    • Organizer
      日本乳癌学会2023シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08926
  • [Presentation] 95GCを用いた乳癌オーダーメイド医療2022

    • Author(s)
      直居靖人
    • Organizer
      日本乳癌学会2022シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08926
  • [Presentation] Curebest 95GCを用いた乳癌再発予後予測2018

    • Author(s)
      直居靖人
    • Organizer
      日本乳癌学会シンポジウム
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      乳癌学会中部地方会2017 ランチョンセミナー
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      23th. Asia pacific cancer conference (APCC), symposium in Seoul
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      日本乳癌学会学術総会2017 プレジデンシャルシンポジウム
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      日本癌治療学会2017 学術セミナー
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      がんと生殖に関するシンポジウム2017 ランチョンセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      第73回 京滋乳癌研究会 特別講演
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      第64回 日本臨床検査医学会学術集会 ランチョンセミナー
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      日本乳癌学会九州地方会2017 ランチョンセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      乳癌最新情報カンファレンス2017 特別講演
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多重遺伝子診断法の開発と臨床応用2017

    • Author(s)
      直居 靖人
    • Organizer
      第15回 日本臨床腫瘍学会学術集会 WS
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] Curebest 95GCによる乳癌再発予後予測2016

    • Author(s)
      直居靖人
    • Organizer
      日本臨床腫瘍学会
    • Place of Presentation
      神戸
    • Year and Date
      2016-06-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 多遺伝子アッセイの開発と乳癌臨床応用2016

    • Author(s)
      直居靖人
    • Organizer
      日本乳癌学会
    • Place of Presentation
      東京
    • Year and Date
      2016-06-22
    • Data Source
      KAKENHI-PROJECT-16K10456
  • [Presentation] 乳癌個別化医療を実現する分子診断の展望2015

    • Author(s)
      直居 靖人
    • Organizer
      日本病理学会総会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2015-05-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461981
  • [Presentation] 乳癌新規バイオマーカー ~予後予測から感受性予測まで2014

    • Author(s)
      直居靖人
    • Organizer
      Osaka breast cancer workshop 2014 招待講演
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461981
  • [Presentation] マイクロアレイによる乳癌の新分類学2014

    • Author(s)
      直居靖人
    • Organizer
      第26回 大阪若手がんセミナー 招待講演
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461981
  • [Presentation] 疾患マーカーの探索と利用

    • Author(s)
      直居靖人
    • Organizer
      第87回 日本生化学会大会 フォーラム 招待講演,2F07
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2014-10-15 – 2014-10-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461981
  • [Presentation] 95GC as a Predictor of Recurrence Risk for ER+/Node- Breast Cancer Patients

    • Author(s)
      直居靖人
    • Organizer
      第114回 日本外科学会定期学術集会 ワークショップ 招待講演
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2014-04-03 – 2014-04-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461981
  • 1.  Shimoda Masafumi (30644455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  加藤 千翔 (10970890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  徳田 由紀子 (50522744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  梁川 雅弘 (00546872)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  鈴木 裕紀 (20845599)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  富山 憲幸 (50294070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  木戸 尚治 (90314814)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  加藤 佑佳 (60729268)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  妹尾 恵太郎 (70822584)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  大庭 輝 (60783412)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  CHIHARA Yoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  及川 将弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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