Kenzo Yamatsugu 山次健三

… Alternative Names

Yamatsugu Kenzo 山次健三

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Researcher Number	30646807
Other IDs
Affiliation (Current)	2025: 千葉大学, 大学院薬学研究院, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 千葉大学, 大学院薬学研究院, 教授 2016 – 2023: 東京大学, 大学院薬学系研究科(薬学部), 助教 2015: 東京大学, 薬学研究科(研究院), 助教 2014: 東京大学, 薬学研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (II) / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Medium-sized Section 37:Biomolecular chemistry and related fields / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Chemical pharmacy / Drug development chemistry Except Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator 触媒 / タンパク質 / アシル化 / 翻訳後修飾 / ヒストン / 細胞内反応 / 環境応答 / リン酸化 / 生理条件 / オキシアニオンホール … More / カルコゲン結合 / メチル化 / 光化学 / 人工修飾 / 人工翻訳後修飾 / 細胞内化学 / エピゲノム / 化学修飾 / 環境 / プローブ / 生細胞内反応 / ピリジン / 化学合成 / ライゲーション / ペプチド / 細胞 / 分子夾雑 / リジン / エピジェネティクス / 有機化学 / 薬学 / ATP / 求核触媒 / ブレンステッド酸 / ホスホエノールビルビン酸 / ホスホエノールピルビン酸 / 水酸基 / タンパク質化学修飾 / 細胞内局在 / acylation / catalyst / protein / subcellular localization / in-cell reaction … More Except Principal Investigator アシル化 / 染色体 / ヒストンアシル化 / エピゲノム修飾 / アシル化触媒 / エピゲノム修復 / DNA損傷 / ヒストン修飾 / エピジェネティク修飾 / エピジェネティクス / DNA修復 / DNA / ヒストン / 触媒 Less

カルコゲン結合は生理条件でのオキシアニオンホール構築に有効か？Principal Investigator
- Principal Investigator
  
  山次健三
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Chiba University
リジン残基メチル化・チロシン残基リン酸化触媒系による生細胞エピゲノム操作の拡充Principal Investigator
- Principal Investigator
  
  山次健三
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Chiba University
Chemical catalyst-driven neo-PTMs in cellsPrincipal Investigator
- Principal Investigator
  
  山次健三
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Chiba University
  The University of Tokyo
In-cell chemical network driven by neo-PTMsArea Organizer
- Area Organizer
  
  山次健三
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
neo-PTMs: Cellular chemical networks created by non-canonical post-translational modificationsPrincipal Investigator
- Principal Investigator
  
  山次健三
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Chiba University
Epigenome manipulation by chemical catalyst-driven abiotic histone acylationPrincipal Investigator
- Principal Investigator
  
  Yamatsugu Kenzo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Chiba University
  The University of Tokyo
Relationships between histone epigenetic modifications and DNA damage repair
- Principal Investigator
  
  Kanai Motomu
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
Studies to develop peptide ligation catalysts enabling easier and faster protein synthesisPrincipal Investigator
- Principal Investigator
  
  Yamatsugu Kenzo
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  The University of Tokyo
分子夾雑下ヒストンアシル化による細胞機能制御を可能にする化学触媒システムの開発Principal Investigator
- Principal Investigator
  
  山次健三
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Direct, catalytic , and site-selective phosphorylation of hydroxy group using molecular recognition and dynamic covalent bondingPrincipal Investigator
- Principal Investigator
  
  Yamatsugu Kenzo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  The University of Tokyo
Regulation of subcellular localization and functions of proteins by in-cell catalytic reactionsPrincipal Investigator
- Principal Investigator
  
  Yamatsugu Kenzo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] pH dependence of perturbed angular correlation in DOTA chelated $$^{111}$$In measured with ring-shape gamma-ray detectors2024
- Author(s)
  Shimazoe Kenji、Donghwan Kim、Mineo Tomoko、Sato Takeshi、Ohta Seiichi、Tatsumi Toshifumi、Sugiyama Akira、Yamatsugu Kenzo、Nomura Sachiyo、Terabayashi Ryohei、Tomita Hideki、Sonoda Tetsu、Shigekawa Yudai、Yokokita Takuya、Uenomachi Mizuki
- Journal Title
  
  Interactions
  
  Volume: 245 Issue: 1 Pages: 22-22
- DOI
  10.1007/s10751-024-01864-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18223, KAKENHI-PROJECT-20KK0174, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018, KAKENHI-ORGANIZER-22H05021, KAKENHI-PLANNED-22H05022, KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-22H04961
[Journal Article] Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin2024
- Author(s)
  Sakata Juri、Tatsumi Toshifumi、Sugiyama Akira, et al.
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 214 Pages: 106375-106375
- DOI
  10.1016/j.pep.2023.106375
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15217, KAKENHI-PROJECT-22KJ0538, KAKENHI-PROJECT-20KK0174, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018, KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-21H02601, KAKENHI-PROJECT-21H02779
[Journal Article] Designer Adaptor Proteins for Functional Conversion of Peptides to Small-Molecule Ligands toward In-Cell Catalytic Protein Modification2023
- Author(s)
  Fujimura Akiko、Ishida Hisashi、Nozaki Tamiko、Terada Shuhei、Azumaya Yuto、Ishiguro Tadashi、Kamimura Yugo R.、Kujirai Tomoya、Kurumizaka Hitoshi、Kono Hidetoshi、Yamatsugu Kenzo、Kawashima Shigehiro A.、Kanai Motomu
- Journal Title
  
  ACS Central Science
  
  Volume: 9 Issue: 11 Pages: 2115-2128
- DOI
  10.1021/acscentsci.3c00930
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19326, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018
[Journal Article] Modulation of the functional interfaces between retroviral intasomes and the human nucleosome2023
- Author(s)
  Mauro E.、Lapaillerie D.、Tumiotto C.、Charlier C.、Martins F.、Sousa S. F.、M?tifiot M.、Weigel P.、Yamatsugu K.、Kanai M.、Munier-Lehmann H.、Richetta C.、Maisch M.、Dutrieux J.、Batisse J.、Ruff M.、Delelis O.、Lesbats P.、Parissi V.
- Journal Title
  
  mBio
  
  Volume: 14
- DOI
  10.1128/mbio.01083-23
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018
[Journal Article] Catalytic Approaches to Chemo- and Site-Selective Transformation of Carbohydrates2023
- Author(s)
  Yamatsugu Kenzo、Kanai Motomu
- Journal Title
  
  Chemical Reviews
  
  Volume: 123 Issue: 10 Pages: 6793-6838
- DOI
  10.1021/acs.chemrev.2c00892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19326, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018
[Journal Article] A chemical catalyst enabling histone acylation with endogenous acyl-CoA2023
- Author(s)
  Habazaki Misuzu、Mizumoto Shinsuke、Kajino Hidetoshi、Kujirai Tomoya、Kurumizaka Hitoshi、Kawashima Shigehiro A.、Yamatsugu Kenzo、Kanai Motomu
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 5790-5790
- DOI
  10.1038/s41467-023-41426-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ0767, KAKENHI-PROJECT-21K19326, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018, KAKENHI-PROJECT-23H05475
[Journal Article] Pathological complete remission of relapsed tumor by photo‐activating antibody-mimetic drug conjugate treatment2022
- Author(s)
  Kaneko Yudai、Yamatsugu Kenzo、Yamashita Takefumi、Takahashi Kazuki、Tanaka Toshiya、Aki Sho、Tatsumi Toshifumi、Kawamura Takeshi、Miura Mai、Ishii Masazumi、Ohkubo Kei、Osawa Tsuyoshi、Kodama Tatsuhiko、Ishikawa Shumpei、Tsukagoshi Masanobu、Chansler Michael、Sugiyama Akira、Kanai Motomu、Katoh Hiroto
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 12 Pages: 4350-4362
- DOI
  10.1111/cas.15565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H02779, KAKENHI-PROJECT-21H02779, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PUBLICLY-20H04819, KAKENHI-ORGANIZER-22H05017
[Journal Article] Live-cell epigenome manipulation by synthetic histone acetylation catalyst system2021
- Author(s)
  Fujiwara Yusuke、Yamanashi Yuki、Fujimura Akiko、Sato Yuko、Kujirai Tomoya、Kurumizaka Hitoshi、Kimura Hiroshi、Yamatsugu Kenzo、Kawashima Shigehiro A.、Kanai Motomu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 4
- DOI
  10.1073/pnas.2019554118
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05527, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-17H01417, KAKENHI-PROJECT-19KK0179, KAKENHI-PROJECT-20H00489, KAKENHI-PROJECT-23K21157
[Journal Article] Live-Cell Protein Modification by Boronate-Assisted Hydroxamic Acid Catalysis2021
- Author(s)
  Adamson Christopher、Kajino Hidetoshi、Kawashima Shigehiro A.、Yamatsugu Kenzo、Kanai Motomu
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 143 Issue: 37 Pages: 14976-14980
- DOI
  10.1021/jacs.1c07060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21472, KAKENHI-PROJECT-19KK0179, KAKENHI-PROJECT-20H00489, KAKENHI-PROJECT-23K21157
[Journal Article] Hydroxamic Acid‐Piperidine Conjugate is an Activated Catalyst for Lysine Acetylation under Physiological Conditions2020
- Author(s)
  Mizumoto Shinsuke、Xi Siqi、Fujiwara Yusuke、Kawashima Shigehiro A.、Yamatsugu Kenzo、Kanai Motomu
- Journal Title
  
  Chemistry - An Asian Journal
  
  Volume: 15 Issue: 6 Pages: 833-839
- DOI
  10.1002/asia.201901737
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04536, KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-19KK0179, KAKENHI-PROJECT-20H00489
[Journal Article] Catalytic Chemoselective O-Phosphorylation of Alcohols2020
- Author(s)
  Domon K.、Puripat M.、Fujiyoshi K.、Hatanaka M.、Kawashima S. A.、Yamatsugu K.、Kanai M.
- Journal Title
  
  ACS Central Science
  
  Volume: 6 Issue: 2 Pages: 283-292
- DOI
  10.1021/acscentsci.9b01272
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06445, KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-17K15420, KAKENHI-PROJECT-20H00489
[Journal Article] Synthetic hyperacetylation of nucleosomal histones2020
- Author(s)
  Kajino Hidetoshi、Nagatani Tomomi、Oi Miku、Kujirai Tomoya、Kurumizaka Hitoshi、Nishiyama Atsuya、Nakanishi Makoto、Yamatsugu Kenzo、Kawashima Shigehiro A.、Kanai Motomu
- Journal Title
  
  RSC Chemical Biology
  
  Volume: 1 Issue: 2 Pages: 56-59
- DOI
  10.1039/d0cb00029a
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04536, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-19KK0179, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-20H00489, KAKENHI-PROJECT-18K19138
[Journal Article] A Stable and Cleavable <i>O</i>-Linked Spacer for Drug Delivery Systems2020
- Author(s)
  Ito Kei、Tatsumi Toshifumi、Takahashi Kazuki、Shimizu Yohei、Yamatsugu Kenzo、Kanai Motomu
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 3 Pages: 212-215
- DOI
  10.1248/cpb.c19-00376
- NAID
  130007804083
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14207, KAKENHI-PUBLICLY-18H04536, KAKENHI-PROJECT-20H00489
[Journal Article] Site-Selective Synthetic Acylation of a Target Protein in Living Cells Promoted by a Chemical Catalyst/Donor System.2019
- Author(s)
  Hamajima W, Fujimura A, Fujiwara Y, Yamatsugu K, Kawashima SA, Kanai M.
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 14 Issue: 6 Pages: 1102-1109
- DOI
  10.1021/acschembio.9b00102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19138, KAKENHI-PROJECT-17K19479, KAKENHI-PUBLICLY-18H04536, KAKENHI-PROJECT-17H01522
[Journal Article] Kinetic analyses and structure-activity relationship studies of synthetic lysine acetylation catalysts2018
- Author(s)
  Yamatsugu Kenzo、Furuta Masahiro、Xi Siqi、Amamoto Yoshifumi、Liu Jiaan、Kawashima Shigehiro A.、Kanai Motomu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 19 Pages: 5359-5367
- DOI
  10.1016/j.bmc.2018.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-18K14273, KAKENHI-PROJECT-17H01522, KAKENHI-PUBLICLY-18H04536
[Presentation] A Catalyst for Epigenome Sensing and Regulation2024
- Author(s)
  山次健三
- Organizer
  日本化学会第104春季年会
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] ヒストンアセチル化レベルの振動形成を指向した光機能化リジンアセチル化触媒の開発2024
- Author(s)
  東屋勇都、上村祐悟、薮田達志、長谷部巴優、汾山美衣、山次健三、川島茂裕、山梨祐輝、松原亮介、金井求
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 人工触媒反応による転写活性化を介した新規抗がん戦略の開発2024
- Author(s)
  山梨祐輝、高丸慎平、東屋勇都、上村祐悟、岡部篤史、海渡智史、鯨井智也、胡桃坂仁志、岩間厚志、金田篤志、山次健三、川島茂裕、金井求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] ヒストンアセチル化レベルの振動形成を指向した光機能化リジンアセチル化触媒の開発2024
- Author(s)
  東屋勇都、上村祐悟、薮田達志、長谷部巴優、汾山美衣、山次健三、川島茂裕、山梨祐輝、松原亮介、金井求
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 極性転換によるチロシンリン酸化反応2024
- Author(s)
  福田　智之、藤吉　浩平、川島　茂裕、三ツ沼　治信、山次健三、金井求
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 人工触媒反応による転写活性化を介した新規抗がん戦略の開発2024
- Author(s)
  山梨祐輝、高丸慎平、東屋勇都、上村祐悟、岡部篤史、海渡智史、鯨井智也、胡桃坂仁志、岩間厚志、金田篤志、山次健三、川島茂裕、金井求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] ヒストンアシル化触媒の拡張を志向した新規ヌクレオソームリガンドの開発2024
- Author(s)
  竹内　悠馬、野崎　多実子、小野田　真由、山次　健三、川島　茂裕、金井　求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] アスパラギン酸側鎖の化学選択的脱炭酸触媒の開発研究2024
- Author(s)
  井上　丈司、山次　健三、三ツ沼　治信、金井　求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] ヒストンアシル化触媒の拡張を志向した新規ヌクレオソームリガンドの開発2024
- Author(s)
  竹内　悠馬、野崎　多実子、小野田　真由、山次　健三、川島　茂裕、金井　求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] ヒストンアセチル化レベルの振動形成を指向した光機能化リジンアセチル化触媒の開発2024
- Author(s)
  東屋勇都、上村祐悟、薮田達志、長谷部巴優、汾山美衣、山次健三、川島茂裕、山梨祐輝、松原亮介、金井求
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] アスパラギン酸側鎖の化学選択的脱炭酸触媒の開発研究2024
- Author(s)
  井上　丈司、山次　健三、三ツ沼　治信、金井　求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2024
- Author(s)
  Kenzo Yamatsugu
- Organizer
  The 4th CCC Mini-Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 極性転換によるチロシンリン酸化反応2024
- Author(s)
  福田　智之、藤吉　浩平、川島　茂裕、三ツ沼　治信、山次健三、金井求
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] アスパラギン酸側鎖の化学選択的脱炭酸触媒の開発研究2024
- Author(s)
  井上　丈司、山次　健三、三ツ沼　治信、金井　求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] A Catalyst for Epigenome Sensing and Regulation2024
- Author(s)
  山次健三
- Organizer
  日本化学会第104春季年会
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] A Catalyst for Epigenome Sensing and Regulation2024
- Author(s)
  山次健三
- Organizer
  日本化学会第104春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 人工触媒反応による転写活性化を介した新規抗がん戦略の開発2024
- Author(s)
  山梨祐輝、高丸慎平、東屋勇都、上村祐悟、岡部篤史、海渡智史、鯨井智也、胡桃坂仁志、岩間厚志、金田篤志、山次健三、川島茂裕、金井求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2024
- Author(s)
  Kenzo Yamatsugu
- Organizer
  The 4th CCC Mini-Symposium, Bangkok
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2024
- Author(s)
  Kenzo Yamatsugu
- Organizer
  The 4th CCC Mini-Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 極性転換によるチロシンリン酸化反応2024
- Author(s)
  福田　智之、藤吉　浩平、川島　茂裕、三ツ沼　治信、山次健三、金井求
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] ヒストンアシル化触媒の拡張を志向した新規ヌクレオソームリガンドの開発2024
- Author(s)
  竹内　悠馬、野崎　多実子、小野田　真由、山次　健三、川島　茂裕、金井　求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  MIT
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞のエピゲノムに合成的に介入する触媒2023
- Author(s)
  山次健三
- Organizer
  第7回　SPIRITS生物ー無機ー有機融合化学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03348
[Presentation] 細胞内のアシルCoAを活性化するヒストンアシル化触媒2023
- Author(s)
  山次健三
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03348
[Presentation] 多様な残基選択性をもつヒストンアシル化触媒のための二価性ヌクレオソームリガンドの開発2023
- Author(s)
  野崎多実子、小野田真由、竹内悠馬、花田華世、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 細胞内人工触媒反応による転写活性化を介した新規抗がん戦略の開発2023
- Author(s)
  山梨　裕輝、上村　祐悟、岡部　篤史、海渡　智史、岩間　厚志、金田　篤志、山次　健三、川島　茂裕、金井　求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 光応答性自己不活性化機構を兼ね備えた機能性タンパク質-薬物複合体の開発2023
- Author(s)
  高橋和希、巽俊文、石井正純、田中十志也、児玉龍彦、杉山暁、山次健三、金井求
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞内アシルCoAを活性化するヒストンアシル化触媒の開発と応用2023
- Author(s)
  幅崎　美涼、水本　真介、梶野　英俊、川島　茂裕、山次　健三、金井　求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Harvard University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 化学触媒による細胞内ヒストンタンパク質の化学修飾と応用2023
- Author(s)
  山次健三
- Organizer
  第23回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  UC Berkeley
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Synthetic Intervention in Cellular Epigenome Network2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  The 3rd Sino-Japanese Symposium on Catalysis for Precision Synthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 細胞膜透過性ペプチドを用いた生細胞内ヒストンアセチル化触媒の開発2023
- Author(s)
  高丸慎平、山梨祐輝、東屋勇都、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] DNA損傷とヒストンアセチル化をポリヌクレオソームに位置選択的に導入できる系の構築2023
- Author(s)
  劉紫昀、席思奇、川島茂裕、山次健三、Jonathan T. Sczepanski、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞内のアシルCoAを活性化するヒストンアシル化触媒2023
- Author(s)
  山次健三
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  LMU Munich
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 極性転換によるチロシンリン酸化反応2023
- Author(s)
  福田　智之、藤吉　浩平、川島　茂裕、三ツ沼　治信、山次健三、金井求
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K27290
[Presentation] DNA損傷とヒストンアセチル化をポリヌクレオソームに位置選択的に導入できる系の構築2023
- Author(s)
  劉紫昀、席思奇、川島茂裕、山次健三、Jonathan T. Sczepanski、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Max-Planck Institute for Coal Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Max-Planck Institute for Coal Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞内のアシルCoAを活性化するヒストンアシル化触媒2023
- Author(s)
  山次健三
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 多様な残基選択性をもつヒストンアシル化触媒のための二価性ヌクレオソームリガンドの開発2023
- Author(s)
  野崎多実子、小野田真由、竹内悠馬、花田華世、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  LMU Munich
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 化学触媒による細胞内ヒストンタンパク質の化学修飾と応用2023
- Author(s)
  山次健三
- Organizer
  第23回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞内人工触媒反応による転写活性化を介した新規抗がん戦略の開発2023
- Author(s)
  山梨　裕輝、上村　祐悟、岡部　篤史、海渡　智史、岩間　厚志、金田　篤志、山次　健三、川島　茂裕、金井　求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  MIT
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  ETH Zurich
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Merck
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 細胞内アシルCoAを活性化するヒストンアシル化触媒の開発と応用2023
- Author(s)
  幅崎　美涼、水本　真介、梶野　英俊、川島　茂裕、山次　健三、金井　求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 細胞のエピゲノムに合成的に介入する触媒2023
- Author(s)
  山次健三
- Organizer
  第7回　SPIRITS生物ー無機ー有機融合化学セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 改変ストレプトアビジン・改変ビオチンを利用した抗がん薬物送達システムの開発2023
- Author(s)
  山次健三
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞内のアシルCoAを活性化するヒストンアシル化触媒2023
- Author(s)
  山次健三
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 極性転換反応を利用したチロシンリン酸化反応の開発2023
- Author(s)
  福田　智之、藤吉　浩平、川島茂裕、山次　健三、金井　求
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  ETH Zurich
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  UC Berkeley
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 多様な残基選択性をもつヒストンアシル化触媒のための二価性ヌクレオソームリガンドの開発2023
- Author(s)
  野崎多実子、小野田真由、竹内悠馬、花田華世、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] アスパラギン酸側鎖の化学選択的脱炭酸触媒の開発研究2023
- Author(s)
  井上　丈司、山次　健三、三ツ沼　治信、金井　求
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K27290
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Merck
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞内ケミカルネットワークを感知し創出するヒストンアシル化触媒2023
- Author(s)
  山次健三
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] エピゲノムへの合成的介入を可能にする化学触媒の開発2023
- Author(s)
  山次健三
- Organizer
  第33回万有福岡シンポジウム
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Stanford University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 改変ストレプトアビジン・改変ビオチンを利用した抗がん薬物送達システムの開発2023
- Author(s)
  山次健三
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Synthetic Intervention in Cellular Epigenome Network2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  The 3rd Sino-Japanese Symposium on Catalysis for Precision Synthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Caltech
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] エピゲノムへの合成的介入を可能にする化学触媒の開発2023
- Author(s)
  山次健三
- Organizer
  第33回万有福岡シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Harvard University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞内ケミカルネットワークを感知し創出するヒストンアシル化触媒2023
- Author(s)
  山次健三
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] DNA損傷とヒストンアセチル化をポリヌクレオソームに位置選択的に導入できる系の構築2023
- Author(s)
  劉紫昀、席思奇、川島茂裕、山次健三、Jonathan T. Sczepanski、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Max-Planck Institute for Coal Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Princeton University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 人工的クロマチン液-液相分離による触媒的ヒストンアシル化反応の加速2023
- Author(s)
  上村祐悟、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞のエピゲノムネットワークに合成的に介入する化学触媒2023
- Author(s)
  山次健三
- Organizer
  第54回先端酵素学研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 極性転換反応によるチロシンリン酸トリエステル化反応の開発研究2023
- Author(s)
  福田智之、藤吉浩平、川島茂裕、山次健三、金井　求
- Organizer
  第84回有機合成化学協会関東支部シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞内アシル CoA を活性化するヒストンアセチル化触媒の開発2023
- Author(s)
  幅崎美涼、渡邉康平、滝田良、水本真介、梶野英俊、川島茂裕、山次健三、金井求
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞膜透過性ペプチドを用いた生細胞内ヒストンアセチル化触媒の開発2023
- Author(s)
  高丸慎平、山梨祐輝、東屋勇都、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞のエピゲノムネットワークに合成的に介入する化学触媒2023
- Author(s)
  山次健三
- Organizer
  第54回先端酵素学研究所セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 極性転換反応によるチロシンリン酸トリエステル化反応の開発研究2023
- Author(s)
  福田智之、藤吉浩平、川島茂裕、山次健三、金井　求
- Organizer
  第84回有機合成化学協会関東支部シンポジウム
- Data Source
  KAKENHI-PROJECT-23K27290
[Presentation] 極性転換反応によるチロシンリン酸トリエステル化反応の開発研究2023
- Author(s)
  福田智之、藤吉浩平、川島茂裕、山次健三、金井　求
- Organizer
  第84回有機合成化学協会関東支部シンポジウム
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 化学触媒による細胞内ヒストンタンパク質の化学修飾と応用2023
- Author(s)
  山次健三
- Organizer
  第23回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞のエピゲノムネットワークに合成的に介入する化学触媒2023
- Author(s)
  山次健三
- Organizer
  第54回先端酵素学研究所セミナー
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 極性転換反応によるチロシンリン酸トリエステル化反応の開発研究2023
- Author(s)
  福田智之、藤吉浩平、川島茂裕、山次健三、金井　求
- Organizer
  第84回有機合成化学協会関東支部シンポジウム
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Merck
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞膜透過性ペプチドを用いた生細胞内ヒストンアセチル化触媒の開発2023
- Author(s)
  高丸慎平、山梨祐輝、東屋勇都、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  UC Berkeley
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Stanford University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Stanford University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Caltech
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 人工的クロマチン液-液相分離による触媒的ヒストンアシル化反応の加速2023
- Author(s)
  上村祐悟、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞内ケミカルネットワークを感知し創出するヒストンアシル化触媒2023
- Author(s)
  山次健三
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  MIT
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 人工的クロマチン液-液相分離による触媒的ヒストンアシル化反応の加速2023
- Author(s)
  上村祐悟、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] ヒストンアセチル化レベルの振動形成を指向した光機能化リジンアセチル化触媒の開発2023
- Author(s)
  東屋勇都、上村祐悟、薮田達志、長谷部巴優、汾山美衣、山次健三、川島茂裕、山梨祐輝、松原亮介、金井求
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K27290
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Princeton University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 細胞のエピゲノムに合成化学的に介入する触媒2023
- Author(s)
  山次健三
- Organizer
  第7回 SPIRITS生物-無機-有機融合化学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 改変ストレプトアビジン・改変ビオチンを利用した抗がん薬物送達システムの開発2023
- Author(s)
  山次健三
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 細胞内人工触媒反応による転写活性化を介した新規抗がん戦略の開発2023
- Author(s)
  山梨　裕輝、上村　祐悟、岡部　篤史、海渡　智史、岩間　厚志、金田　篤志、山次　健三、川島　茂裕、金井　求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  ETH Zurich
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Caltech
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  LMU Munich
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] Synthetic Intervention in Cellular Epigenome Network2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  The 3rd Sino-Japanese Symposium on Catalysis for Precision Synthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] エピゲノムへの合成的介入を可能にする化学触媒の開発2023
- Author(s)
  山次健三
- Organizer
  第33回万有福岡シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞内アシルCoAを活性化するヒストンアシル化触媒の開発と応用2023
- Author(s)
  幅崎　美涼、水本　真介、梶野　英俊、川島　茂裕、山次　健三、金井　求
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Harvard University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome2023
- Author(s)
  Kenzo Yamatsugu
- Organizer
  Princeton University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 位置選択性を制御可能なヒストンアシル化触媒システム2022
- Author(s)
  野崎多実子、竹内悠馬、花田華世、山次健三、川島茂裕、金井求
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 合成的エピゲノムを拓く化学触媒の開発研究2022
- Author(s)
  山次健三
- Organizer
  第48回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03348
[Presentation] 新規の光活性化物質の開発2022
- Author(s)
  山次健三
- Organizer
  第20回メディカル・イノベーション・ワークショップ
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 合成的エピゲノムを拓く化学触媒の開発研究2022
- Author(s)
  山次健三
- Organizer
  第48回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 細胞内アセチルCoAを活性化するヒストンアセチル化触媒の開発2022
- Author(s)
  幅崎美涼、梶野英俊、水本真介、川島茂裕、山次健三、金井求
- Organizer
  日本化学会　第102春季年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 細胞のエピゲノムに合成化学的に介入する触媒2022
- Author(s)
  山次健三
- Organizer
  第7回SPIRITS生物-無機-有機融合化学セミナー
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞のエピゲノムに介入できる有機分子触媒2022
- Author(s)
  山次健三
- Organizer
  第24回　ケムステVシンポ　有機分子触媒
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 合成的エピゲノムを拓く化学触媒の開発研究2022
- Author(s)
  山次健三
- Organizer
  第48回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-ORGANIZER-22H05017
[Presentation] 細胞のエピゲノムに介入できる有機分子触媒2022
- Author(s)
  山次健三
- Organizer
  第24回　ケムステVシンポ　有機分子触媒
- Invited
- Data Source
  KAKENHI-PROJECT-19H03348
[Presentation] Synthetic Epigenetics Enabled by Chemical Catalysts2022
- Author(s)
  Kenzo Yamatsugu
- Organizer
  ICPAC Kota Kinabalu 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03348
[Presentation] Synthetic Epigenetics Enabled by Chemical Catalysts2022
- Author(s)
  Kenzo Yamatsugu
- Organizer
  ICPAC Kota Kinabalu 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05018
[Presentation] 合成的エピゲノムを拓く化学触媒の開発研究2022
- Author(s)
  山次健三
- Organizer
  第48回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] Synthetic Epigenetics Enabled by Chemical Catalysts2022
- Author(s)
  Kenzo Yamatsugu
- Organizer
  ICPAC Kota Kinabalu 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 位置選択性を制御可能なヒストンアシル化触媒システム2021
- Author(s)
  野崎多実子、花田華世、山次健三、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会　第１５回年会
- Data Source
  KAKENHI-PROJECT-21K19326
[Presentation] 高い官能基許容性を有する水酸基の触媒的単段階リン酸化反応の開発2019
- Author(s)
  山次健三、土門憲史、Maneeporn Puripat、畑中美穂、川島茂裕、金井求
- Organizer
  日本ケミカルバイオロジー学会第１４回年会
- Data Source
  KAKENHI-PROJECT-17K15420
[Presentation] ヒストンに翻訳後修飾を導入する化学触媒2019
- Author(s)
  山次健三
- Organizer
  日本薬学会第１３９年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04536
[Presentation] 触媒的無保護リン酸エステル化反応の開発2018
- Author(s)
  土門憲史、山次健三、金井求
- Organizer
  第４４回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15420
[Presentation] ヒストンアセチル化人工触媒の開発と触媒医療への取り組み2017
- Author(s)
  山次健三
- Organizer
  富士フイルム
- Place of Presentation
  富士フイルム先進研究所（神奈川県、足柄上郡）
- Invited
- Data Source
  KAKENHI-PROJECT-26460142
[Presentation] 新規疾病治療法の確立を目標とした触媒的化学修飾による標的タンパク質の細胞内局在制御法の開発研究2017
- Author(s)
  濱島航、石黒伸茂、川島茂裕、山次健三、金井求
- Organizer
  日本薬学会第１３７年会
- Place of Presentation
  東北大学（宮城県、仙台）
- Data Source
  KAKENHI-PROJECT-26460142
[Presentation] 触媒医療の実現に向けて：人工触媒システムによるヒストンの合成的アシル化（２）2017
- Author(s)
  山次健三、川島茂裕
- Organizer
  日本薬学会第１３７年会
- Place of Presentation
  東北大学（宮城県、仙台）
- Invited
- Data Source
  KAKENHI-PROJECT-26460142

1. Kanai Motomu (20243264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 川島茂裕 (40508115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 藤村亜紀子 (80793091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山梨祐輝 (40979150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 島津忠広 (10618771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 五月女宜裕 (50431888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ITO YUMA

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 木村宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 上ノ町水紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 畑中美穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 坂田樹理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 杉山暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kenzo Yamatsugu 山次 健三

Yamatsugu Kenzo 山次 健三

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カルコゲン結合は生理条件でのオキシアニオンホール構築に有効か？Principal Investigator

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リジン残基メチル化・チロシン残基リン酸化触媒系による生細胞エピゲノム操作の拡充Principal Investigator

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Chemical catalyst-driven neo-PTMs in cellsPrincipal Investigator

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In-cell chemical network driven by neo-PTMsArea Organizer

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neo-PTMs: Cellular chemical networks created by non-canonical post-translational modificationsPrincipal Investigator

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Epigenome manipulation by chemical catalyst-driven abiotic histone acylationPrincipal Investigator

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Relationships between histone epigenetic modifications and DNA damage repair

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Studies to develop peptide ligation catalysts enabling easier and faster protein synthesisPrincipal Investigator

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分子夾雑下ヒストンアシル化による細胞機能制御を可能にする化学触媒システムの開発Principal Investigator

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Direct, catalytic , and site-selective phosphorylation of hydroxy group using molecular recognition and dynamic covalent bondingPrincipal Investigator

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Regulation of subcellular localization and functions of proteins by in-cell catalytic reactionsPrincipal Investigator

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[Journal Article] pH dependence of perturbed angular correlation in DOTA chelated $$^{111}$$In measured with ring-shape gamma-ray detectors2024

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[Journal Article] Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin2024

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[Journal Article] Designer Adaptor Proteins for Functional Conversion of Peptides to Small-Molecule Ligands toward In-Cell Catalytic Protein Modification2023

Author(s)

Kenzo Yamatsugu 山次健三

Yamatsugu Kenzo 山次健三