Suzuki Nobumi 鈴木伸三

… Alternative Names

Nobumi Suzuki 鈴木伸三

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Researcher Number	30723746
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医学部附属病院, 助教 2020 – 2023: 東京大学, 医学部附属病院, 助教 2021: 東京大学, 医学部附属病院, 特任臨床医 2019: 東京大学, 医学部附属病院, 特任臨床医 2019: 公益財団法人朝日生命成人病研究所, その他部局等, 教授 … More 2016: 公益財団法人朝日生命成人病研究所, その他部局等, 教授(移行) 2016: 公益財団法人朝日生命成人病研究所, 消化器科, 消化器部長 2015: 公益財団法人朝日生命成人病研究所, その他部局等, 教授 2014: 東京大学, 医学部附属病院, その他 Less
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator マウス / GAPPS / APC / 胃がん / オルガノイド / 大腸がん / NKcell / 大腸癌 / 胃癌 / ピロリ菌 … More Except Principal Investigator … More 抗PD-1抗体 / PD-1 / PD-L1 / S-1 / 5-FU / 胃癌 / 消化管 / オルガノイド / 分化 / 腸管 / 発生 / DLK1 / 胎児 / 小腸 / 分化誘導 / 幹細胞 / 癌 / 胃食道接合部 Less

未成熟間質シグナルによる腸管免疫成熟機構の解明Principal Investigator
- Principal Investigator
  
  鈴木伸三
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
フッ化ピリミジン製剤による胃癌PD-L1発現制御機序の解明とPD-1抗体耐性の克服
- Principal Investigator
  
  朴成和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
The mechanism of carcinogenesis of GAPPSPrincipal Investigator
- Principal Investigator
  
  鈴木伸三
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Stromal epithelial crosstalk during small intestinal development by Dlk1.
- Principal Investigator
  
  Minami Yuka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
MSS大腸癌における間質を標的としたNKcell治療薬の探索Principal Investigator
- Principal Investigator
  
  鈴木伸三
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
  The Institute for Adult Diseases Asahi Life Foundation
NK cell resistance acquisition in MSS colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Suzuki Nobumi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
New stomach cancer model mouse using Cre expression H. pyloriPrincipal Investigator
- Principal Investigator
  
  Nobumi Suzuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The Institute for Adult Diseases Asahi Life Foundation
Analysis of cancer stem cell of esophagogastric junction
- Principal Investigator
  
  Hirata Yoshihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2016 2015 2014

All Journal Article Presentation

[Journal Article] Upper gastrointestinal involvement of Behcet's disease in Japan: endoscopic findings and clinical features2024
- Author(s)
  Murakami Keita、Arai Junya、Ihara Sozaburo、Tsuchida Yumi、Shoda Hirofumi、Tsuboi Mayo、Kurokawa Ken、Shiomi Chihiro、Suzuki Nobumi、Hayakawa Yoku、Fujio Keishi、Fujishiro Mitsuhiro
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 39 Issue: 4 Pages: 708-715
- DOI
  10.1111/jgh.16479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16007, KAKENHI-PROJECT-22K08028, KAKENHI-PROJECT-21K07976
[Journal Article] The Association between Diverticular Rebleeding and Early-Morning Blood Pressure and Surge: A Prospective Observational Trial2023
- Author(s)
  Arai Junya、Niikura Ryota、Yamada Atsuo、Aoki Tomonori、Suzuki Nobumi、Tsuji Yosuke、Hayakawa Yoku、Kawai Takashi、Fujishiro Mitsuhiro
- Journal Title
  
  Digestion
  
  Volume: 104 Issue: 5 Pages: 400-408
- DOI
  10.1159/000531099
- Data Source
  KAKENHI-PROJECT-22K08028, KAKENHI-PROJECT-21K07976
[Journal Article] Association of probiotic use with nivolumab effectiveness against various cancers: A multicenter retrospective cohort study2023
- Author(s)
  Arai Junya、Niikura Ryota、Hayakawa Yoku、Suzuki Nobumi、Honda Tetsuro、Okamura Takuma、Hasatani Kenkei、Yoshida Naohiro、Nishida Tsutomu、Sumiyoshi Tetsuya、Kiyotoki Shu、Ikeya Takashi、Arai Masahiro、Boku Narikazu、Fujishiro Mitsuhiro
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 16 Pages: 16876-16880
- DOI
  10.1002/cam4.6313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08028, KAKENHI-PROJECT-23K07393, KAKENHI-PROJECT-23K07448, KAKENHI-PROJECT-21K07976
[Journal Article] Engineered bacteria detect tumor DNA2023
- Author(s)
  Cooper Robert M.、Wright Josephine A.、Ng Jia Q.、Goyne Jarrad M.、Suzuki Nobumi、Lee Young K.、Ichinose Mari、Radford Georgette、Ryan Feargal J.、Kumar Shalni、Thomas Elaine M.、Vrbanac Laura、Knight Rob、Woods Susan L.、Worthley Daniel L.、Hasty Jeff
- Journal Title
  
  Science
  
  Volume: 381 Issue: 6658 Pages: 682-686
- DOI
  10.1126/science.adf3974
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15828, KAKENHI-PROJECT-22K08028, KAKENHI-PROJECT-22K20935
[Journal Article] Comments on “Epidemiology of overall and early‐onset serrated polyps versus conventional adenomas in a colonoscopy screening cohort”2023
- Author(s)
  Arai Junya、Aoki Tomonori、Hayakawa Yoku、Niikura Ryota、Suzuki Nobumi、Fujishiro Mitsuhiro
- Journal Title
  
  International Journal of Cancer
  
  Volume: 152 Issue: 11 Pages: 2433-2435
- DOI
  10.1002/ijc.34445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08028
[Journal Article] Severe obstructive colitis treated with repeated colonoscopic decompression2023
- Author(s)
  Arai Junya、Suzuki Nobumi、Hayakawa Yoku、Matzuzaki Hiroyuki、Yokoyama Yuichiro、Aoki Tomonori、Ishibashi Rei、Odawara Nariaki、Ihara Sozaburo、Tsuji Yosuke、Ishihara Soichiro、Fujishiro Mitsuhiro
- Journal Title
  
  DEN Open
  
  Volume: 4 Issue: 1
- DOI
  10.1002/deo2.233
- Data Source
  KAKENHI-PROJECT-21K07976
[Journal Article] Risk and preventive factors of early‐onset colorectal neoplasms: endoscopic and histological database analysis2022
- Author(s)
  Arai Junya、Aoki Tomonori、Hayakawa Yoku、Niikura Ryota、Ishibashi Rei、Suzuki Nobumi、Tsuji Yosuke、Yamada Atsuo、Ushiku Tetsuo、Fujishiro Mitsuhiro
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 38 Issue: 2 Pages: 259-268
- DOI
  10.1111/jgh.16045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07976, KAKENHI-PROJECT-22K08028
[Journal Article] Efficacy of Early Video Capsule Endoscopy for Acute Overt Lower Gastrointestinal Bleeding with Colonic Diverticulosis: A Prospective Observational Study2022
- Author(s)
  Aoki Tomonori、Yamada Atsuo、Niikura Ryota、Nakada Ayako、Suzuki Nobumi、Hayakawa Yoku、Hirata Yoshihiro、Koike Kazuhiko、Fujishiro Mitsuhiro
- Journal Title
  
  Digestion
  
  Volume: 103 Issue: 5 Pages: 367-377
- DOI
  10.1159/000525314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08028
[Journal Article] Chemoprevention for Colorectal Cancers: Are Chemopreventive Effects Different Between Left and Right Sided Colorectal Cancers?2022
- Author(s)
  Arai Junya、Suzuki Nobumi、Niikura Ryota、Ooki Daisuke、Kawahara Takuya、Honda Tetsuro、Hasatani Kenkei、Yoshida Naohiro、Nishida Tsutomu、Sumiyoshi Tetsuya、Kiyotoki Shu、Ikeya Takashi、Arai Masahiro、Ishibashi Rei、Aoki Tomonori、Tsuji Yosuke、Yamamichi Nobutake、Hayakawa Yoku、Fujishiro Mitsuhiro
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 67 Issue: 11 Pages: 5227-5238
- DOI
  10.1007/s10620-022-07431-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07976, KAKENHI-PROJECT-22K08028
[Journal Article] Inhibiting SCAP/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis2022
- Author(s)
  Kawamura Satoshi、Matsushita Y、Kurosaki S、Tange M、Fujiwara N、Hayata Y、Hayakawa Y、Suzuki N、Hata M、Tsuboi M、Kishikawa T、Kinoshita H、Nakatsuka T、Sato M、Kudo Y、Hoshida Y、Umemura A、Eguchi A、Ikenoue T、Hirata Y、Uesugi M、Tateishi R、Tateishi Keisuke、Fujishiro Mitsuhiro、Koike K、Nakagawa H
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 132 Issue: 11
- DOI
  10.1172/jci151895
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08028, KAKENHI-PROJECT-21H02892
[Journal Article] Clinicopathological Features of Gastric Cancer with Autoimmune Gastritis2022
- Author(s)
  Arai Junya、Niikura Ryota、Hayakawa Yoku、Suzuki Nobumi、Hirata Yoshihiro、Ushiku Tetsuo、Fujishiro Mitsuhiro
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 4 Pages: 884-884
- DOI
  10.3390/biomedicines10040884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07976
[Journal Article] Delineating proinflammatory microenvironmental signals by ex vivo modeling of the immature intestinal stroma2021
- Author(s)
  Ichinose Mari、Suzuki Nobumi、Wang Tongtong、Wright Josephine A.、Lannagan Tamsin R. M.、Vrbanac Laura、Kobayashi Hiroki、Gieniec Krystyna、Ng Jia Q.、Ihara Souzaburo、Mavrangelos Chris、Hayakawa Yoku、Hughes Patrick、Worthley Daniel L.、Woods Susan L.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-86675-4
- Data Source
  KAKENHI-PROJECT-19K17478
[Journal Article] Axin2+ Peribiliary Glands in the Periampullary Region Generate Biliary Epithelial Stem Cells That Give Rise to Ampullary Carcinoma2021
- Author(s)
  Hayata Yuki、Nakagawa Hayato、Kurosaki Shigeyuki、Kawamura Satoshi、Matsushita Yuki、Hayakawa Yoku、Suzuki Nobumi、Hata Masahiro、Tsuboi Mayo、Kinoshita Hiroto、Miyabayashi Koji、Mizutani Hiroya、Nakagomi Ryo、Ikenoue Tsuneo、Hirata Yoshihiro、Arita Junichi、Hasegawa Kiyoshi、Tateishi Keisuke、Koike Kazuhiko
- Journal Title
  
  Gastroenterology
  
  Volume: 160 Issue: 6 Pages: 2133-2148.e6
- DOI
  10.1053/j.gastro.2021.01.028
- Data Source
  KAKENHI-PROJECT-19K17478
[Journal Article] Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development2021
- Author(s)
  Ichinose Mari、Suzuki Nobumi、et al.
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology
  
  Volume: 320 Issue: 4 Pages: 506-520
- DOI
  10.1152/ajpgi.00445.2020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17478, KAKENHI-PROJECT-21K07976
[Journal Article] Dysregulated Immune Responses by ASK1 Deficiency Alter Epithelial Progenitor Cell Fate and Accelerate Metaplasia Development during H. pylori Infection.2020
- Author(s)
  Hayakawa, Y.; Hirata, Y.; Hata, M.; Tsuboi, M.; Oya, Y.; Kurokawa, K.; Abe, S.; Arai, J.; Suzuki, N.; Nakagawa, H.; Fujiwara, H.; Tateishi, K.; Maeda, S.; Koike, K
- Journal Title
  
  Microorganisms
  
  Volume: 8 Issue: 12 Pages: 1-20
- DOI
  10.3390/microorganisms8121995
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08377, KAKENHI-PROJECT-20H03656, KAKENHI-PROJECT-19K17478, KAKENHI-PROJECT-20K08323, KAKENHI-PROJECT-18KT0067
[Journal Article] Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation2019
- Author(s)
  Fujiwara H、Tateishi K、Misumi K、Hayashi A、Igarashi K、Kato H、Nakatsuka T、Suzuki N、Yamamoto K、Kudo Y、Hayakawa Y、Nakagawa 、Tanaka Y、Ijichi H、Kogure H、Nakai Y、Isayama H、Hasegawa K、Fukayama M、Soga T、Koike K
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 18859-18859
- DOI
  10.1038/s41598-019-55211-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-19K17391, KAKENHI-PROJECT-19K17478, KAKENHI-PROJECT-17K09454, KAKENHI-PROJECT-18K07899, KAKENHI-PROJECT-18K07900
[Journal Article] Alpha-Blockers As Colorectal Cancer Chemopreventive: Findings from a Case?Control Study, Human Cell Cultures, and In Vivo Preclinical Testing2019
- Author(s)
  Suzuki Nobumi、Niikura Ryota、Ihara Sozaburo、Hikiba Yohko、Kinoshita Hiroto、Higashishima Naoko、Hayakawa Yoku、Yamada Atsuo、Hirata Yoshihiro、Nakata Ryo、Okamoto Makoto、Sano Munetaka、Kushiyama Akifumi、Ichinose Mari、Woods Susan L.、Worthley Daniel、Iwamoto Yasuhiko、Koike Kazuhiko
- Journal Title
  
  Cancer Prevention Research
  
  Volume: 12 Issue: 3 Pages: 185-194
- DOI
  10.1158/1940-6207.capr-18-0288
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09347, KAKENHI-PROJECT-18K07933, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K15928, KAKENHI-PROJECT-19K17478
[Journal Article] Mouse Model for Cholangiocarcinoma from Peribiliary Glands.2019
- Author(s)
  Nakagawa H, Suzuki N, Koike K.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1905 Pages: 237-245
- DOI
  10.1007/978-1-4939-8961-4_21
- ISBN
  9781493989607, 9781493989614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17478
[Journal Article] Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis2018
- Author(s)
  Lannagan Tamsin R M、,,,、Hayakawa Yoku,,, Worthley Daniel L、Woods Susan L
- Journal Title
  
  Gut
  
  Volume: 68 Issue: 4 Pages: 684-692
- DOI
  10.1136/gutjnl-2017-315920
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07933, KAKENHI-PROJECT-19K17478
[Journal Article] Gastric Metaplasia Induced by Helicobacter pylori Is Associated with Enhanced SOX9 Expression via Interleukin-1 Signaling.2015
- Author(s)
  Serizawa T, Hirata Y, Hayakawa Y, Suzuki N, Sakitani K, Hikiba Y, Ihara S, Kinoshita H, Nakagawa H, Tateishi K, Koike K.
- Journal Title
  
  Infection and Immunity
  
  Volume: 84 Issue: 2 Pages: 562-572
- DOI
  10.1128/iai.01437-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19315
[Presentation] GAPPS（家族性胃底腺ポリポーシス）モデルマウスの開発2022
- Author(s)
  鈴木　伸三
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-22K08028
[Presentation] A novel mouse model of Gastric Adenocarcinoma andProximal Polyposis of the Stomach (GAPPS) mimics the human disease.2019
- Author(s)
  Nobumi Suzuki
- Organizer
  AGITG Annual Scientific Meeting, 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17478
[Presentation] Analysis of cancer initiating cell of squamo-columnar junction2016
- Author(s)
  Hirata Y, Kinoshita H, Suzuki N, Nakagawa H, Ihara S, Hayakawa Y, Koike K
- Organizer
  アジア環太平洋消化器病学会週間
- Place of Presentation
  神戸
- Year and Date
  2016-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460934
[Presentation] 胃食道接合部癌幹細胞の検討2014
- Author(s)
  平田　喜裕、鈴木　伸三、小池　和彦
- Organizer
  日本消化器関連学会週間
- Place of Presentation
  神戸
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-26460934

1. Hirata Yoshihiro (10529192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. Minami Yuka (80724658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 山田篤生 (80534932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 早河翼 (60777655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 畑昌宏 (90892505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 朴成和 (50505948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANAKA Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 建石良介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 市瀬茉里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 井原聡三郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Nobumi 鈴木 伸三

Nobumi Suzuki 鈴木 伸三

Research Projects

Research Products

Co-Researchers

未成熟間質シグナルによる腸管免疫成熟機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

フッ化ピリミジン製剤による胃癌PD-L1発現制御機序の解明とPD-1抗体耐性の克服

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of carcinogenesis of GAPPSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Stromal epithelial crosstalk during small intestinal development by Dlk1.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

MSS大腸癌における間質を標的としたNKcell治療薬の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

NK cell resistance acquisition in MSS colorectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New stomach cancer model mouse using Cre expression H. pyloriPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cancer stem cell of esophagogastric junction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Upper gastrointestinal involvement of Behcet's disease in Japan: endoscopic findings and clinical features2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Association between Diverticular Rebleeding and Early-Morning Blood Pressure and Surge: A Prospective Observational Trial2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of probiotic use with nivolumab effectiveness against various cancers: A multicenter retrospective cohort study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Engineered bacteria detect tumor DNA2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comments on “Epidemiology of overall and early‐onset serrated polyps versus conventional adenomas in a colonoscopy screening cohort”2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Severe obstructive colitis treated with repeated colonoscopic decompression2023

Author(s)

Suzuki Nobumi 鈴木伸三

Nobumi Suzuki 鈴木伸三