Liu Xueying 劉学瑩

… Alternative Names

劉学瑩リュウガクケイ

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Researcher Number	30777470
Affiliation (Current)	2025: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 主任研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 主任研究員 2021 – 2023: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 研究員 2017 – 2019: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 90120:Biomaterials-related Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related / Basic Section 50010:Tumor biology-related / Tumor therapeutics
Keywords	Principal Investigator Medulloblastoma / pH-triggered / Chemo-immunotherapy / childhood cancers / chemo-immunotherapy / medulloblastoma / ICIs / Nanomedicine Except Principal Investigator 核酸医薬 / 膵臓がん … More / ナノ治療薬 / 炎症抑制 / 標的化 / 肺線維症 / ドラッグデリバリーシステム / BBB in vitroモデル / Exosome / transfer DDS / 抗体医薬 / 脳 / アンチジーン核酸 / 生体適合性高分子 / 機能性核酸 / 核酸医薬デリバリー / 脳疾患 / 核酸デリバリー / ナノ医薬 / 薬物送達システム / 抗PD-1抗体 / 併用 / HYAL / MMP / 耐性克服 / がん間質 / リモデリング / 膵臓癌 / 腫瘍間質 / ECM分解 / がん間質再構築 / ゲムシタビン / 免疫チェックポイント阻害剤 / エピルビシンミセル / 癌 / ナノバイオ / ナノミセル / 癌幹細胞阻害剤 / MDR-1 / ミセル / エピルビシン / スタウロスポリン / K252a ミセル / 難治癌 / がん幹細胞 Less

Development of a Targeted Therapeutic Approach for Idiopathic Pulmonary Fibrosis Using a Drug Delivery System Loaded with Ligand-Nucleic Acid Pharmaceuticals
- Principal Investigator
  
  喜納宏昭
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
脳内神経細胞への抗体医薬送達を実現するtransfer DDSの創出
- Principal Investigator
  
  安楽泰孝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Institute of Science Tokyo
Nanomedicine-based Chemo-Immunotherapy for the Treatment of Pediatric Brain CancerPrincipal Investigator
- Principal Investigator
  
  劉学瑩
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
Development of nano-therapeutic agents to overcome immune checkpoint inhibitor resistance due to tumor stroma of intractable cancer
- Principal Investigator
  
  KINOH HIROAKI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
Development of advanced nanomedicines for brain-targeted oligonucleotide delivery
- Principal Investigator
  
  Miyata Kanjiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Creation of novel nanomedicine targeting drug-resistant cancer stem cells in recurrent refractory cancer
- Principal Investigator
  
  Kinoh Hiroaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine

All 2023 2022 2021 2020 2019 2017

All Journal Article Presentation Patent

[Journal Article] Identifying molecular tags selectively retained on the surface of brain endothelial cells to generate artificial targets for therapy delivery.2023
- Author(s)
  48.G. M. Porro, I. Lorandi, X. Liu, K. Kataoka, G. Battaglia, D. G.-Carter,
- Journal Title
  
  Fluids Barriers CNS
  
  Volume: 20 Issue: 1 Pages: 88-88
- DOI
  10.1186/s12987-023-00493-6
- Data Source
  KAKENHI-PROJECT-22K12833
[Journal Article] Conjugation of glucosylated polymer chains to checkpoint blockade antibodies augments their efficacy and specificity for glioblastoma2021
- Author(s)
  T. Yang X. Liu, H. Zhou, J. Xie, Y. Mochida, H. Kinoh, H. Cabral, K Kataoka
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 5 Issue: 11 Pages: 1274-1287
- DOI
  10.1038/s41551-021-00803-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02774, KAKENHI-PROJECT-20H04524
[Journal Article] Nanomedicines blocking adaptive signals in cancer cells overcome tumor TKI resistance.2020
- Author(s)
  H. Kinoh, H. Shibasaki, X. Liu, T. Yamasoba, H. Cabral, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 321 Pages: 132-144
- DOI
  10.1016/j.jconrel.2020.02.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-20H04524
[Journal Article] Single-stranded DNA-packaged polyplex micelle as adeno-associated-virus-inspired compact vector to systemically target stroma-rich pancreatic cancer.2019
- Author(s)
  T. A. Tockary, W. Foo, A. Dirisala, Q. Chen, S. Uchida, S. Osawa, Y. Mochida, X. Liu, H. Kinoh, H. Cabral, K. Osada, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 13 Issue: 11 Pages: 12732-12742
- DOI
  10.1021/acsnano.9b04676
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K19901
[Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.2019
- Author(s)
  Y. Yi, H. J. Kim, M. Zheng, P. Mi, M. Naito, B. S. Kim, H. S. Min, K. Hayashi, F. Perche, K. Toh, X. Liu, Y. Mochida, H. Kinoh, H. Cabral, K. Miyata, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 295 Pages: 268-277
- DOI
  10.1016/j.jconrel.2019.01.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K18378, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-18K18379
[Journal Article] Therapeutic polymersome nanoreactors with tumor-specific activable cascade reactions for cooperative cancer therapy.2019
- Author(s)
  W. Ke, J. Li, F. Mohammed, Y. Wang, K. Tou, X. Liu, P. Wen, H. Kinoh, Y. Anraku, H. Chen, K. Kataoka, Z. Ge,
- Journal Title
  
  ACS Nano
  
  Volume: 13 Pages: 2357-2369
- DOI
  10.1021/acsnano.8b09082
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-17K20094
[Journal Article] In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers2019
- Author(s)
  Watanabe Sumiyo、Hayashi Kotaro、Toh Kazuko、Kim Hyun Jin、Liu Xueying、Chaya Hiroyuki、Fukushima Shigeto、Katsushima Keisuke、Kondo Yutaka、Uchida Satoshi、Ogura Satomi、Nomoto Takahiro、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1894-1894
- DOI
  10.1038/s41467-019-09856-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-19K12799, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-18H02797, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H02098
[Journal Article] Effective treatment of drug resistant recurrent breast tumors harboring cancer stem-like cells by staurosporine/epirubicin co-loaded polymeric micelles2017
- Author(s)
  J. Zhang, H. Kinoh, L. Hespel, X. Liu, S. Quader, J. Martin, T. Chida, H. Cabral, K. Kataoka,
- Journal Title
  
  Journal of Controlled Release, "Vol. 264, pp. 127-1335, 2017
  
  Volume: 264 Pages: 127-135
- DOI
  10.1016/j.jconrel.2017.08.025
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16F16731, KAKENHI-PROJECT-16K12904
[Patent] ストローマリッチな腫瘍を治療又は予防するための医薬組成物2022
- Inventor(s)
  喜納　宏昭、カダール　サビーナ、劉　学螢、片岡　一則
- Industrial Property Rights Holder
  喜納　宏昭、カダール　サビーナ、劉　学螢、片岡　一則
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] Chemo-immunotherapy of nanomedicine and ICI for reprogramming tumor microenvironment to overcome ICI-resistance.2023
- Author(s)
  H. Kinoh, H. Cabral, X. Liu, S. Quader, K. Kataoka,
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] Chemo-immunotherapy of nanomedicine and ICI for reprogramming tumor microenvironment to overcome ICI-resistance2023
- Author(s)
  H. Kinoh, H. Cabral, X. Liu, S. Quader, K. Kataoka
- Organizer
  The 14th Annual World Cancer Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] Effective and specific navigation of immune checkpoint blockade antibodies to glioblastoma by the glucose-PEGylation technology2023
- Author(s)
  Y. Mochida, T. Yang, X. Liu, H. Kinoh, H. Cabral, K. Kataoka
- Organizer
  The 13th SPSJ International Polymer Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] 集束超音波と高分子複合体を組み合わせた脳選択的AAV送達システムの構築2023
- Author(s)
  喜納宏昭,本田雄士,松平望,Liu Xueying,片岡一則,西山伸宏
- Organizer
  第4回超音波分子診断治療研究会
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] Polymeric Nanomedicine targets brain cancer.2023
- Author(s)
  S. Quader, X. Liu, H. Kinoh, H. Cabral, K. Kataoka
- Organizer
  The 13th SPSJ International Polymer Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] Chemo-Immunotherapy of Epirubicin micelle and anti-PD-1 antibody for Reprogramming Tumor Microenvironment to Overcome anti-PD-1 antibody-Resistance.2023
- Author(s)
  H. Kinoh, H. Cabral, X. Liu, S. Quader, K. Kataoka
- Organizer
  7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] Chemo-Immunotherapy of Nanomedicine and anti-PD-1 antibody for Reprogramming Tumor Microenvironment to Overcome anti-PD-1 antibody-Resistance .2022
- Author(s)
  喜納宏昭、カブラルオラシオ、クワドラサビーナ、劉学螢、片岡一則
- Organizer
  7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] Targeting Intractable Cancers Using Extracellular pH sensitive NanoMedicine2019
- Author(s)
  S. Quader, X. Liu, H. Kinoh, K. Kataoka
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07234
[Presentation] Nanomedicine Loading Staurosporine homolog (K252a-hydrozyde) overcomes osimertinib resistance in non small lung cancer2019
- Author(s)
  喜納宏昭、柴崎仁志、S. Quader、X. Liu、H. Cabral、片岡一則
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07234

1. Kinoh Hiroaki (70283067)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
2. Cabral Horacio (10533911)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. Quader Sabina (90749699)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 藤加珠子 (90342732)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Miyata Kanjiro (50436523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 谷口陽祐 (00452714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 林光太朗 (00780660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 安楽泰孝 (60581585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 出口芳春 (40254255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Mohamed Aziz・Awaad・Aziz (50978286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 内田智士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 野本貴大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Liu Xueying 劉 学瑩

劉 学瑩 リュウ ガクケイ

Research Projects

Research Products

Co-Researchers

Development of a Targeted Therapeutic Approach for Idiopathic Pulmonary Fibrosis Using a Drug Delivery System Loaded with Ligand-Nucleic Acid Pharmaceuticals

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳内神経細胞への抗体医薬送達を実現するtransfer DDSの創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Nanomedicine-based Chemo-Immunotherapy for the Treatment of Pediatric Brain CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of nano-therapeutic agents to overcome immune checkpoint inhibitor resistance due to tumor stroma of intractable cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of advanced nanomedicines for brain-targeted oligonucleotide delivery

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of novel nanomedicine targeting drug-resistant cancer stem cells in recurrent refractory cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identifying molecular tags selectively retained on the surface of brain endothelial cells to generate artificial targets for therapy delivery.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conjugation of glucosylated polymer chains to checkpoint blockade antibodies augments their efficacy and specificity for glioblastoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nanomedicines blocking adaptive signals in cancer cells overcome tumor TKI resistance.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-stranded DNA-packaged polyplex micelle as adeno-associated-virus-inspired compact vector to systemically target stroma-rich pancreatic cancer.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic polymersome nanoreactors with tumor-specific activable cascade reactions for cooperative cancer therapy.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effective treatment of drug resistant recurrent breast tumors harboring cancer stem-like cells by staurosporine/epirubicin co-loaded polymeric micelles2017

Author(s)

Journal Title

DOI

Liu Xueying 劉学瑩

劉学瑩リュウガクケイ