SAKABE Takeshi 坂部武史

… Alternative Names

坂部武文サカベタケフミ

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Researcher Number	40035225
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Affiliation (based on the past Project Information) *help	2008: 山口大学, 医学系研究科, 教授 2007 – 2008: Yamaguchi University, Graduate School of Medicine, Professor 2006: Yamaguchi Univ., Graduate School of Medicine, Professor, 大学院医学系研究科, 教授 1991 – 2005: 山口大学, 医学部, 教授 1987 – 1990: 山口大学, 医学部, 助教授 1986: 山口大, 医学部, 助教授
Review Section/Research Field	Principal Investigator 麻酔学 / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / 麻酔学 / Medical sociology
Keywords	Principal Investigator 高気圧酸素 / 脳虚血 / hypothermia / 虚血性神経細胞死 / 前脳虚血 / 神経伝達物質 / spinal cord ischemia / calpain / calpastatin / fodrin … More / calpain inhibitor-1 / 中枢神経 / 虚血耐性 / 虚血 / 耐性誘導 / 耐性関連因子 / 脳虚血耐性 / p38 / 海馬CA1 / Nitrous oxide / Analgesia / Acute tolerance / Substance P-receptor / Monoamine / 麻酔薬 / 笑気 / ハロセン / ペントバルビタ-ル / モルヒネ / ノルアドレナリン / α_2受容体 / インビトロオ-トラジオグラフィ- / anesthetics / analgesics / nitrous oxide / halothane / pentobarbital / morphine / noradrenaline / alpha-2 receptor / in vitro autoradiography / 低酸素性脳症 / 代謝性脳症 / 遅発性神経細胞壊死 / 興奮性神経伝達物質 / マイクロダイアリス / 細胞内情報伝達系 / 薬物療法 / 海馬CA_1 / 記憶障害 / セカンドメッセンジャ- / brain ischemia / delayed neuronal death / neurotransmitter derangements / intracellular signal transduction / microdialysis / neurobehavioral disturbance / drug theraphy / 一過性脊髄虚血 / 脊髄血流量 / 対麻痺 / 一酸化窒素 / 興奮性アミノ酸 / 低体温 / spinal cord blood flow / paraplegia / nitric oxide / excitatory amino acid / 細胞骨格タンパク質 / 脳低温 / 細胞内情報伝達 / カルパイン / カルパスタチン / 細胞骨格蛋白 / フォドリン / cerebral ischemia / ischemic neuronal death / cytoskeleton / 脊髄虚血 / 家兎 / ネクローシス / アポトーシス / マイクログリア / アストロサイト / マイクロファージ / グリア細胞TUNEL染色 / アガロース電気泳動法 / Nauta染色 / GFAP / RAM-11 / ストレス蛋白 / rabbit / necrosis / apoptosis / microglia / astrocyte / macrophage / 耐性関連遺伝子 / 中枢神絳 / 高圧酸素 / Central nervous system / Ischemic tolerance / Hyperbaric oxygen / Genomic response / 神経栄養因子 / 免疫・炎症 / p38 MAPK / クロストレランス / 遺伝子 / hyperbric oxygen / ischemic tolerance / forebrain ischemia / neurotrophin / immuno / inflammatory response / p38 MAP kinase / エンフルレン麻酔 / 痙攣 / 局所脳代謝 / 血流 / エンフルレン / Enflurane anesthesia / Seizures / Brain metabolism … More Except Principal Investigator 家兎 / 脳虚血 / 脳浮腫 / Spinal glutamate / 海馬 / HE染色 / 脊髄虚血 / 血液脳関門 / Spinal cord / NMDA antagonist / 脊髄 / アポトーシス / rabbit / 心室筋 / 虚血 / カルシウム / 脳梗塞 / 中大脳動脈閉塞 / ラット / 虚血耐性 / 神経細胞傷害 / 前脳虚血 / スナネズミ / 免疫ブロッティング法 / インスリン様成長因子1 / 脂肪塞栓 / カルシウム蓄積 / 記憶障害 / Analgesia / Tolerance / G Protein / Adenylate cyclase / Protein kinase C / Ca channel / Nitric oxide / 鎮痛 / Pain / Spinal sensitization / PKC / NGF / モルヒネ / Apoptosis / 神経毒性 / 局所麻酔薬 / 脊椎麻酔 / グルタミン酸 / Neurotoxicity / Ras / manumycin A / apoptosis / Medical futility / basal lamina / triolein / GFAP / matrix metalloproteinase / SF-36 / spinal cord ischemia / paraplegia / insulin / 脳水分量 / 凍結乾燥法 / 膠質浸透圧 / 膠質輸液 / ニコチン性アセチルコリン受容体 / ベクロニウム / mRNA / 卵母細胞 / 膜電位固定法 / アセチルコリン / 麻酔薬 / フラー2 / フラ-2 / カルシウム拮抗薬 / 脳虚血耐性 / 局所脳虚血 / アデノシン / アデノシンA_1受容体 / DPCPX / プロテアソーム / エリスロポエチン / Lipopolysaccharide / 全身炎症反応 / 術後高次脳機能障害 / LPS / 脂肪塞 / 炎症反応 / 虚血性神経細胞障害 / 神経伝達物質 / 受容体 / 薬物治療 / マイクロダイアリ-シス / brain ischemia / ischemic neuronal damage / neurotransmitter / receptor / Ca accumulation / memory disturbance / drug theraphy / microdialysis / 虚血後再潅流 / 経眼窩的中大脳動脈閉塞 / 血管原性脳浮腫 / 脳充血 / 虚血性脳障害 / 虚血後再灌流 / Brain ischemia / Reperfusion / Transorbital occlusion of middle cerebral artery / Blood-brain barrier / Vasogenic cerebral edema / N-type Ca channel / α2-receptor / Intracellular spinal transduction / 耐性発現 / オピオイド / モノアミン / α_2受容体 / 情報伝達系 / G蛋白質 / アデニル酸シクラーゼ / Ilyperalgesia / 疼痛 / 脊髄過敏 / 痛覚過敏 / 触覚過敏 / 脊髄マイクロダイアリス / グルタメート放出 / プロテインキナーゼC / 神経成長因子 / 細胞内情報伝達系 / Cキナーゼ / 細胞骨格蛋白 / 神経栄養因子 / シナプス可塑性 / 脱抑制機構 / Hyperalgesia / 急性硬膜下血腫 / NMDA受容体拮抗薬 / 脳障害 / 硬膜下血腫 / 頭蓋内圧 / 脳代謝 / 脳循環 / acute subdural hematoma / brain injuries / rat / イソフルラン / 中枢神経 / ミダゾラム / 電気刺激 / 鎮通 / 局所脳脊髄代謝 / 吸入麻酔薬 / 静脈麻酔薬 / 麻酔作用機序 / Isoflurane / Morphine / central nervous system / spinal cord / midazolam / electric stimulation / analgesia / local cerebral and spinal metabolic rate / 神経因性疼痛, / 神経可塑性, / 脊髄グルタメート, / c-fos表現, / アポトーシス, / 介在ニューロン死, / 栄養因子治療 / 神経因性疼痛 / 神経可塑性 / 脊髄グルタメート / c-fos発現 / 介在ニューロン死 / Neuropathic pain / Central sensitization / Neurotrophic factor / Cytokines / Neuropathic Pain / Neuronal Prasticity / C-fos Expression / Necrosis of Interneurons / Treatment of Nerve Growth Factor / 脊髄麻酔 / Local anesthetics / Spinal anesthesia / Rabbits / Glutamate / 遅発性神経細胞死 / 免疫ブロッティング / TUNEL染色 / H-Ras / Manumycin A / 神経学的スコア / 非アポトーシス的細胞死 / Bc1-2 / forebrain / ischemia-reperfusion / immunoblotting / neuron / hippocampus / 乏突起細胞 / local anesthetics / glutamate / oligodendrocyte / 重症度評価 / 予後予測 / 医療介入度 / 治療断念 / Futility / 絶望的瀕死患者 / Severity of illness index / Outcome prediction / ミトコンドリア / シクロスポリンA / 遅発性運動機能障害 / 遅発性運動神経障害 / 遅発生運動神経障害 / Spinal cord ischemia / Mitochondria / Cyclosporin A / Delayed onset motor dysfunct / Rabbit / オピオイド受容体 / 全脳虚血 / ナロキソン / 虚血耐性様現象 / ischemic tolerance / opioid receptors / neuronal injury / gerbil / forebrain ischemia / hippicampus / hematoxylin-eosin staining / naloxone / 脳脂肪塞栓 / アストロサイト / アクアポリン4 / matrix metalloroteinase / fat embolism / brain edema / astrocyte / aquaporin / 原発性手掌・腋窩多汗症 / 健康関連尺度 / 胸腔鏡下交換神経遮断術 / 交換神経皮膚反応 / 事象関連電位 / 術前検査・術後検査 / 施術適応 / 胸腔鏡下交感神経遮断術 / 交感神経皮膚反応 / 前検査・術後検査 / 手術適応 / 原発性手掌・腋窩 / primary hyperhidrosis / health-related quality of life / endoscopic thoracic sympathetectomy / sympathetic skin responce / event related potential / pre / post-operative examination / indication of operation / インスリン / 対麻痺 / insulin-like growth factor1 / insulin-like growth factor-1 / 局所脳代謝 / 局所脳血流量 / 受容体結合 / Brain Ischemia / Local Cerebral Blood Flow / Local Cerebral Glucose Utilization / Ca Accumulation / Receptor Binding Less

高気圧酸素による虚血耐性誘導を応用した脳血管障害の新規予防・治療戦略の開発Principal Investigator
- Principal Investigator
  
  坂部武史
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Effects of erythropoietin and insulin-like growth factor 1 on the outcome after transient spinal cord ischemia and the mechanism in the signal transduction
- Principal Investigator
  
  MATSUMOTO Mishiya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
The effect of systemic inflammation to ischemic brain damage and hypothermic protection
- Principal Investigator
  
  ISHIDA Kazuyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
プロテアソームを介する虚血耐性現象の獲得に関する研究
- Principal Investigator
  
  福田志朗
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Mechanism for ischemic crosstoleance in central nervous system and its therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  SAKABE Takefumi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
A new role of insulin in the protection against ischemic spinal cord injury
- Principal Investigator
  
  MATSUMOTO Mishiya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Sympathetic skin response evoked by electrical stimulation of the thoracic sympathetic trunk as intraoperative monitor of endoscopic thoracic sympathectomy. -Health-related quality of life among patients with palmer hyperhidrosis who underwent endoscopic thoracic sympathetectomy.-
- Principal Investigator
  
  KAWAI Kouji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
The role of mitochondrial dysfunction in the delayed onset motor neuron death after transient cord ischemia
- Principal Investigator
  
  MATSUMOTO Mishiya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Research on acquisition of ischemic-tolerance-like phenomenon intermediated by opioid receptors
- Principal Investigator
  
  FUKUDA Shirou
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Astrocytic response, profiles of aquaporin 4 and matrix metalloproteinase contribution to the process of brain edema formation in the fat embolism and focal brain ischemia model in rat
- Principal Investigator
  
  ISHIDA Kazuyoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
脳虚血耐性発現におけるアデノシンの関与と効果的薬物投与法に関する研究
- Principal Investigator
  
  中木村和彦
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Investigation on therapeutic potentials of inducing ischemic tolerance against ischemic neuronal damage in the spinal cordPrincipal Investigator
- Principal Investigator
  
  SAKABE Takefumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Variations in decision making for seriously ill hospitalized patients among institutions
- Principal Investigator
  
  KUNIHIRO Mitsuru
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical sociology
- Research Institution
  Yamaguchi University
The mechanism of axonal injury and regeneration after intrathecal administration of local anesthetics
- Principal Investigator
  
  MATSUMOTO Mishiya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
脳虚血後の神経細胞傷害と傷害抑制に関する研究 -アポトーシスおよび非アポトーシス性傷害の検討-
- Principal Investigator
  
  FUKUDA Shirou
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
The machanism of delayed motor neuron death after transient spinal cord ischemiaPrincipal Investigator
- Principal Investigator
  
  SAKABE Takefumi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
The mechanism for neurotoxicity of local anesthetics
- Principal Investigator
  
  MATSUMOTO Mishiya
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Elucidation of Molecular and Neurobiological Mechanism in Pathophysiological Pain following Peripheral Injury
- Principal Investigator
  
  ISHIKAWA Toshizo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Effects of intrathecal or intra-cerebral ventricular midazolam on the tail flick and local cerebral and spinal metabolic responses to preripheral stimulation during isoflurane anesthesia and morphine-induced analgesia in the rat
- Principal Investigator
  
  NAKAKIMURA Kazuhiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
The pathogenesis and treatment of cerebral ischemia based on the mechanism of cytoskeletal changesPrincipal Investigator
- Principal Investigator
  
  SAKABE Takefumi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
虚血時および再潅流時の心筋細胞内カルシウム濃度変化に及ぼすカルシウム拮抗薬の効果
- Principal Investigator
  
  大下修造
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Elucidation of Molecular Mechanisms of Pain : Role of PKC and NGF on spinal sensitization in the pathological state following peripheral tissue injury
- Principal Investigator
  
  ISHIKAWA Toshizo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
A study on the mechanism and treatment during lucid interval in a rat model of acute subdural hematoma
- Principal Investigator
  
  NAKAKIMURA Kazuhiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
心室筋の細胞内カルシウム濃度に及ぼすアシドーシス,低酸素,麻酔薬の相互作用
- Principal Investigator
  
  大下修造
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Experimental studies of pathophysiology and treatment of spinal cord ischemiaPrincipal Investigator
- Principal Investigator
  
  SAKABE Takefumi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
胎児型および成体型ニコチン性アセチルコリン受容体に対する筋弛緩薬、麻酔薬の効果
- Principal Investigator
  
  大下修造
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
Involvement of receptor-mediated regulation of Ca channel and second messengers in pain transmission and modulation
- Principal Investigator
  
  ISHIKAWA Toshizoh
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
The role of intracellular signal transducing system in hypoxia/ischemiainduced brain damage : Therapeutic values of mild hypothermia and drugsPrincipal Investigator
- Principal Investigator
  
  SAKABE Takefumi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
脳浮腫モデルによる麻酔薬と脳浮腫治療法の相互作用に関する研究
- Principal Investigator
  
  KAIEDA Reiji
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
Study on Rule of Neurotransmitter Derangement in Ischemic Brain Damage
- Principal Investigator
  
  ISHIKAWA Toshizoh, TAKESHITA Hiroshi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
The Role of Alpha-2 Adrenergic Receptors in the Action of Anesthetics and AnalgesicsPrincipal Investigator
- Principal Investigator
  
  SAKABE Takefumi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
Pathophysiology of Hypermia and Effects of Reducing Blood Flow at the Immediate Post-Ischemia in the Brain.
- Principal Investigator
  
  TATEISHI Akio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
Pathophysiology and Treatment of Brain Ischemia
- Principal Investigator
  
  TAKESHITA Hiroshi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
Central nervous system effect of enflurane.Principal Investigator
- Principal Investigator
  
  SAKABE Takefumi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University
笑気の鎭痛作用及び耐性発生機序に関する研究Principal Investigator
- Principal Investigator
  
  坂部武史
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  Yamaguchi University

All 2009 2008 2007 2006 2005 2004 2002

All Journal Article Presentation

[Journal Article] The temporal profile of genomic responses and protein synthesis in ischemic tolerance of the rat brain induced by repeated hyperbaric oxygen2007
- Author(s)
  Takao, Hirata, Ying, Jun, Cue, Takeshi, Funakoshi, Yoichi, Mizukami,Yu-ichiro, Ishikawa, Futoshi, Shibasaki, Mishiya, Matsumoto, Takefumi, Sakabe
- Journal Title
  
  Brain Research 1130(1)
  
  Pages: 214-222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390429
[Journal Article] The Brain and Spinal Cord Preconditioning for the protection against Ischemic Injury2007
- Author(s)
  Mishiya, Matsumoto, Kazuyoshi, Ishida, Takefumi, Sakabe
- Journal Title
  
  Masui 56
  
  Pages: 285-297
- NAID
  40015345751
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390429
[Journal Article] Ischemic preconditioning in the central nervous system2005
- Author(s)
  Mishiya, Matsumoto, Kazuhiko, Nakakimura, Mitsuyoshi, Yoshida, Takao, Hirata, Takefumi, Sakabe
- Journal Title
  
  Japanese Journal of Reanimatology 24
  
  Pages: 76-81
- NAID
  10016606516
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390429
[Journal Article] 脳におけるPreconditioningと麻酔2004
- Author(s)
  坂部武史他
- Journal Title
  
  臨床麻酔 28(9)
  
  Pages: 1471-1480
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370490
[Journal Article] Preconditioning in central nervous system and anesthesia2004
- Author(s)
  Takefumi Sakabe, et al.
- Journal Title
  
  Rinshomasui 28(9)
  
  Pages: 1471-1480
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370490
[Journal Article] 脳におけるPreconditioningと麻酔2004
- Author(s)
  坂部武史他
- Journal Title
  
  臨床麻酔 28・9
  
  Pages: 1471-1480
- Data Source
  KAKENHI-PROJECT-14370490
[Journal Article] Application of ischemic tolerance-induction to protection of the brain and spinal cord.2004
- Author(s)
  Takefumi Sakabe, et al.
- Journal Title
  
  LiSA 11(1)
  
  Pages: 16-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370490
[Journal Article] 徹底分析シリーズ脳を守るスロラテージー1 虚血耐性誘導の脳・脊髄保護法への応用2004
- Author(s)
  坂部武史他
- Journal Title
  
  LiSA 11(1)
  
  Pages: 16-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370490
[Journal Article] Ischemic preconditioning in the brain ans spinal cord.2002
- Author(s)
  Takefumi Sakabe, et al.
- Journal Title
  
  ICU & CCU 26(12)
  
  Pages: 1007-1017
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370490
[Journal Article] 脳・脊髄の虚血耐性2002
- Author(s)
  坂部武史他
- Journal Title
  
  ICUとCCU 26(12)
  
  Pages: 1007-1017
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370490
[Presentation] 一過性脊髄虚血後の神経障害に対するerythropoietin とinsulin-like growth factor 1 の保護効果2009
- Author(s)
  吉村学、松本美志也、山下敦生、若松弘也、福田志朗、石田和慶、坂部武史
- Organizer
  第13回日本神経麻酔・集中治療研究会
- Place of Presentation
  大阪
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19591797
[Presentation] Cognitive dysfunction and cognitive behavial impairment in cardiac and non-cardiac surgery2009
- Author(s)
  Kazuyoshi Ishida, Takefumi Sakabe
- Organizer
  The 2009 annual meeting of americain society of anesthesiologist
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-19591799
[Presentation] 脳蘇生の歴史と新たな治療戦略-虚血耐性2009
- Author(s)
  坂部武史
- Organizer
  第13回日本神経麻酔・集中治療研究会
- Place of Presentation
  大阪千里ライフサイエンスセンター
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20659245
[Presentation] Repeated Hyperbaric Oxygen Can Induce Neuroprotection against Forebrain Ischemia in Rats via Suppresion of p38 Mitogen Activated Protein Kinase2009
- Author(s)
  Takefumi Sakabe, et al
- Organizer
  2009 Annual Meeting The International Anesthesi a Research Society
- Place of Presentation
  米国サンディエゴ
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20659245
[Presentation] Neuroprotective synergy of erythropoietin and insulin-like growth factor 1 demonstrated in a spinal cord ischemia model in rabbits2008
- Author(s)
  Mishiya Matsumoto, Manabu Yoshimura, Atsuo Yamashita, Hiroya Wakamatsu, Shiro Fukuda, kazuyoshi Ishida, Takefumi Sakabe
- Organizer
  First congress of Asian society for neuroanesthesia and critical care
- Place of Presentation
  中国北京
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-19591797
[Presentation] 麻酔後の高次脳機能障害及び日常生活動作の変化-心臓大血管手術VS整形外科手術-2008
- Author(s)
  石田和慶、坂部武史(シンポジウム)
- Organizer
  日本麻酔科学会第55回学術集会
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19591799
[Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen in rat brain : Time window and genome-wide gene and protein expression2007
- Author(s)
  Takao, Hirata, Ying, Jun Cui, Takeshi, Funakoshi, Yoichi, Mizukami, Yu-ichiro, Ishikawa, Futoshi, Shibasaki, Mishiya, Matsumoto, Takefumi, Sakabe
- Organizer
  The 8th International Conference on Quantification of Brain Function with PET
- Place of Presentation
  Osaka, Japan
- Year and Date
  2007-05-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390429
[Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen in rat brain : Time window and genome-wide gene and protein expression2007
- Author(s)
  Takao, Hirata, Ying, Jun, Cui, Takeshi, Funakoshi, Yoichi, Mizukami, Yu-ichiro, Ishikawa, Futoshi, Shibasaki, Mishiya, Matsumoto, Takefumi, Sakabe
- Organizer
  The 23rd International Symposium on Cerebral Blood Flow, Metabolism and Function
- Place of Presentation
  Osaka, Japan
- Year and Date
  2007-05-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390429
[Presentation] 心臓大血管手術及び整形手術後の高次脳機能および日常生活動作の変化に関する検討2007
- Author(s)
  石田和慶、坂部武史
- Organizer
  日本心臓血管麻酔学会第12回学術大会
- Year and Date
  2007-09-16
- Data Source
  KAKENHI-PROJECT-19591799
[Presentation] Ischemic tolerance and genomic responses induced by hyperbaric oxygen2006
- Author(s)
  Takao, Hirata, Ying, Jun, Cui, Mishiya, Matsumoto, Takefumi, Sakabe
- Organizer
  The 53rd Annual Meeting of Japanese Society of Anesthesiologists
- Place of Presentation
  Kobe, Japan
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390429
[Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen in rat brain2006
- Author(s)
  Hirata, T, Cui, YJ, Funakoshi, T, Mizukami, Y, Ishikawa, Y, Shibasaki, F, Matsumoto, M, Sakabe, T
- Organizer
  The 2nd Japan-China-Kores Joint Symposium for Neuroanesthesia
- Place of Presentation
  Osaka
- Year and Date
  2006-04-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390429

1. ISHIKAWA Toshizoh (90034991)

# of Collaborated Projects: 16 results

# of Collaborated Products: 0 results
2. MATSUMOTO Mishiya (60243664)

# of Collaborated Projects: 16 results

# of Collaborated Products: 9 results
3. NAKAKIMURA Kazuhiko (50180261)

# of Collaborated Projects: 15 results

# of Collaborated Products: 0 results
4. FUKUDA Shirou (70322245)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
5. IIDA Yasuhiko (90304485)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. MAEKAWA Tsuyoshi (60034972)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. YAMASHITA Atsuo (50379971)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. ISHIDA Kazuyoshi (80314813)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
9. HIRATA Takao (40420533)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
10. 大下修造 (60144945)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. SANO Takanobu (40243670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KAWAI Koji (30274161)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KAIEDA Reiji (10204306)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. MIZUKAMI Youichi (80274158)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
15. TAKESHITA Hiroshi (50034898)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. TATEISHI Akio (00155102)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. NAGAI Ikuo (30145536)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. MORIMOTO Yasuhiro (60325230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. SOEJIMA Yoshiyuki (20206676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 伴隆志 (50101069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. WAKAMATSU Hiroya (80379966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. YAMAMOTO Tomohisa (10144940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. DAIKAI Sadamitsu (10187164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KURODA Yasuhiro (80234615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TSUKAHARA Masato (20136188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. FURUKAWA Syoei (90159129)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. KAWATA Ryuuichi (20263783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. NAKAI Akira (60252516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. KUNIHIRO Mitsuru (40284252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. FUKUMOTO Youhei (90136193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. YAMASE Hiroaki (90279357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. INOUE Yuuji (80213180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. MURAKAWA Toshisuke (30201809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 佐伯仁 (80379958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 筒井俊徳 (00155417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. YOSHIMURA Manabu

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

SAKABE Takeshi 坂部 武史

坂部 武文 サカベ タケフミ

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高気圧酸素による虚血耐性誘導を応用した脳血管障害の新規予防・治療戦略の開発Principal Investigator

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Mechanism for ischemic crosstoleance in central nervous system and its therapeutic applicationPrincipal Investigator

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Investigation on therapeutic potentials of inducing ischemic tolerance against ischemic neuronal damage in the spinal cordPrincipal Investigator

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SAKABE Takeshi 坂部武史

坂部武文サカベタケフミ