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TOKORO Toshiharu  所 敏治

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TOKORO T.  所 敏治

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Researcher Number 40112841
Affiliation (based on the past Project Information) *help 1999 – 2000: 東京慈恵会医科大学, 医学部, 講師
1991 – 1994: Jikei Univ. Pediatrics assistant prof., 医学部, 講師
1993: 東京慈恵会医科大学, 医学部・小児科, 講師
1993: lecturer, 小児科, 講師
1990: 東京慈恵会医科大学, 小児科, 講師 … More
1990: Jikei Univ. Prof. asst., 小児科学, 講師
1989: 東京慈恵会医科大学, 医学部小児科, 助手
1988 – 1989: 東京慈恵会医科大学, 小児科, 助手 Less
Review Section/Research Field
Principal Investigator
Pediatrics
Except Principal Investigator
Pediatrics
Keywords
Principal Investigator
Lysosomal disorder / Niemann-Pick mouse / Twitcher mouse / Psychosine / Krabbe's disease / (5)Twitcherマウス / (4)培養オリゴデンドロサイト / (3)脱髄 / (2)サイコシン / (1)krabbe病 … More / E-64 / 神経培養 / ライソゾ-ム病 / ニ-マンピック病 / Twitcherマウス / サイコシン / クラベ病 / Cytkine / Adenovirus Vector / Niemann-Pick Disease TypeC / Neural progenitor / Nieman-Pick病typeC / Niemann-Pick病type C / アデノウイルスベクター / サイトカイン / レトロウイルス / β-galactosidase / Nieman-Pick病type C / retroviral vector / deficient cholesterol esterification / fetus gene therapy / Niemann-Pick disease type C / コレステロールエステル / Ca代謝 / 脳血液関門 / アデノウィルスベクター / 胎児肝臓 / Lacz遺伝子 / レトロウィルスベクター / コレステロールのエステル化障害 / レトロウイルスベクター / 胎児遺伝子治療 / ヒトニーマンピック病タイプC / CDS mouse / SPM mouse / Cross hybridization / Genetic homogenity / Cholesterol esterification / Niemann-Pick Disease / 胎児肝細胞移植 / 細胞内転送機構 / コレステロ-ルエステル / コレステロ-ル / NemannーPick病 / スフィンゴシェリン / 遺伝学的類似性 / エステル化障害 / CSDマウス / SPMマウス / ニーマンピック病 / スフィンゴミエリン … More
Except Principal Investigator
MLD / 遺伝子解析 / 遺伝子治療 / 異染性脳白質変性症 / レトロウイルスベクター / Gaucher病 / オリゴデンドログリア細胞 / サイコシン / PCR-SSCP / Arylsulfatase A / RT-PCR / Gaucher Disease / 遺伝型と臨床型 / アリルスルファターゼA遺伝子 / アデノウイルスベクター / SSCP / ASO / PCR / PMD / PCR-SSCP法 / ArylsulfataseA / 遺伝子変異解析 / RT-PCR法 / matachromatic leukodystrophy(MLD) / 先天性ミエリン形成異常症 / demyelination / gene therapy / genotype / Krabbe's disease / Metachromatic / Gaucher disease / スプライスアクセプターサイト / PCR法 / 制限酵素 / ゴーシェ病 / ミエリン形成異常症 / 呼吸鎖リン酸化反応 / 脱髄 / クラベ病 / 異染性白質変性症 / Nerve Growth Factor / 遺伝子変異 / Glucocerebrosidase / mannnose terminal / neuronal cell / blood brain barrier / liposome / αーマンノ-ス含有リポゾ-ム / 培養神経細胞 / α_2ーマクログロブリン / 酵素補充療法 / 脳障害 / リポゾ-ム / マンノ-ス / cerebrosideβ-galactosidase / グリア細胞 / リボゾ-ム / 酵素抗体染色 / ^ース / cerebrosideーβーgalactoside / 酵素補充法 / 脳血液関門 / multiple sulfatase deficiency / ライソゾ-ム酵素 / リン酸化障害 / アルチプルサルファタ-ゼ欠損症 / アリルサルファタ-ゼA / マルチプルサルファタ-ゼ欠損症 / NGF receptor / Signal Transduction / Psychosine / Nimann-Pick Disease / Krabbe Disease / レトロウイルスベクタ- / Niemann-Pichマウス / 動物モデル / リポゾ-ム療法 / マンノ-ス含有オリゴ糖 / Blood Brain barrier / スフィンゴミエリナ-ゼ / twitcherマウス / NiemannーPick病マウス / NGFRカスケ-ド / NGF / NGFRcDNA / golgiーlysosomal complex / コレステロ-ル / NiemannーPickマウス / Krabbe病 / サルファターゼ / オリゴデンドロサイト / レトロウイルス / アデノウイルス / GLD培養細胞 / ガラクトサミン / スフィンゴシングルコサイコシン / 中枢神経培養細胞 / ガラクトシ-ルーβーガラクトシダ-ゼ Less
  • Research Projects

    (11 results)
  • Co-Researchers

    (19 People)
  •  Treatment for congenital metabolic disorder with brain dysfunction.Principal Investigator

    • Principal Investigator
      TOKORO Toshiharu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The Jikei University School of Medicine
  •  リピドーシス動物モデルを用いての中枢神経障害の遺伝子治療

    • Principal Investigator
      衛藤 義勝
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Jikei University School of Medicine
  •  Molecular Analysis and Gene Therapy in Inherited dysmyelinating disorder

    • Principal Investigator
      MAEKAWA Kihei
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      The Jikei University School of Medicine
  •  Gene therapy for inherited neurodegenerative disease using fetal bone marrows stem cell transplantation.Principal Investigator

    • Principal Investigator
      TOKORO Toshiharu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The Jikei Univ.School of Medicine
  •  Studies of genetic analysis and gene therapy for myelin-associated disorders.

    • Principal Investigator
      MAEKAWA Kihei
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      The Jikei University School of Medicine
  •  Genetic analysis of Niemann-Pick model mouse.Principal Investigator

    • Principal Investigator
      TOKORO Toshoharu
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Jikei Univ.School of Medicine
  •  リピド-シスマウス神経細胞に於けるガングリオシド代謝とその機能異常の解明

    • Principal Investigator
      ETO Y.
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jikei University School of Medicine
  •  Cellular engineering for treatment of animal model for inherited brain disorder

    • Principal Investigator
      MAEKAWA K.
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Jikei University School of Medicine
  •  Pathogenesis of Multiple Sulfatase Deficiency

    • Principal Investigator
      ETO Yoshikatsu
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Jikei University School of Medicine
  •  Modified enzyme which target to neuronal cells to cross blood brain barrier

    • Principal Investigator
      ETO Yoshikatsu
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Jikei University School of Medicine
  •  The Pathogenesis of Demyelination in Krabbe's disease and it's therapyPrincipal Investigator

    • Principal Investigator
      TOKORO Toshiharu
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The Jikei University School of Medicine, Department of Pediatrics
  • 1.  ETO Y. (50056909)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  IDA Hiroyuki (90167255)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  ITO F. (10057010)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  OHASHI T. (60160595)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  UMEZAWA Fusayo (50185063)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  MAEKAWA K. (80056613)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  長谷川 頼康 (60256435)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SASAKI Nobuhiko (50170684)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TATSUSHIMA H. (70190460)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  津田 隆 (50188554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  奈良 隆寛 (80180537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SAKURAI S. (20056542)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  五味渕 一三 (50205621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TOYODA Shigeru (90110931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KUSANO Kaoru (80205070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ONO Tsuneya (60147288)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  大野 京子 (10301524)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  小林 博司 (90266619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SEKIGUCHI Shigeru (90119818)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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