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HASHIMOTO Etuko  橋本 悦子

ORCIDConnect your ORCID iD *help
Researcher Number 40130273
Affiliation (based on the past Project Information) *help 2014 – 2017: 東京女子医科大学, 医学部, 教授
1998 – 1999: 東京女子医科大学, 医学部, 講師
Review Section/Research Field
Except Principal Investigator
Digestive surgery / Urology / Gastroenterology
Keywords
Except Principal Investigator
Interferon-α / HCV / p62遺伝子欠損マウス / エストラジオール / 非アルコール性脂肪性肝疾患 / クッパー細胞 / 臓器連関 / LPS / 遺伝子改変マウス / 性差 … More / 非アルコール性脂肪性肝炎 / 臓器連環 / 転写因子 / 女性ホルモン / 肝癌 / 脂肪性肝炎 / renal transplantation / インターフェロン / 慢性腎不全 / C型肝炎 / 腎移植 / 非アルコール性脂肪肝炎(NASH) / 肝癌(HCC) / 非アルコール性脂肪肝炎 (NASH) / EpCAM / Nanog / stemness遺伝子 / 非アルコール性脂肪肝炎 / hepatocellular carcinoma / stemness marker / steatohepatitis Less
  • Research Projects

    (3 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (15 People)
  •  Pathophysiological mechanism for the high incidence of overeating-induced obesity, NASH and hepatic carcinogenesis in post-menoposal women

    • Principal Investigator
      Yamamoto Masakazu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Tokyo Women's Medical University
  •  Expression status of stemness-related genes in nonalcoholic steatohepatitis and clarification of the carcinogenesis mechanism

    • Principal Investigator
      Kogiso Tomomi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Women's Medical University
  •  Effect of Interferon-α treatment for HCV-positive renal transplant recipients and hempdialysed patients.

    • Principal Investigator
      TANABE Kazunari
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Department of Urology, Kidney Center, Tokyo Women's Medical University

All 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

  • [Book] PBCの診断 第4巻『難治性肝疾患の診療を極める』2014

    • Author(s)
      小木曽智美、谷合麻紀子、橋本悦子.
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Book] Fluid management renaissance2014

    • Author(s)
      小木曽智美、徳重克年、橋本悦子.
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.2018

    • Author(s)
      Kawaguchi T, Shima T, Mizuno M, Mitsumoto Y, Umemura A, Kanbara Y, Tanaka S, Sumida Y, Yasui K, Takahashi M, Matsuo K, Itoh Y, Tokushige K, Hashimoto E, Kiyosawa K, Kawaguchi M, Itoh H, Uto H, Komorizono Y, Shirabe K, Takami S, Takamura T, Kawanaka M, Yamada R, Matsuda F, Okanoue T
    • Journal Title

      PLoS One

      Volume: 13

    • NAID

      120006398880

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04935
  • [Journal Article] The Relationship between the Growth Hormone/Insulin-like Growth Factor System and the Histological Features of Nonalcoholic Fatty Liver Disease2017

    • Author(s)
      Chishima S, Kogiso T, Matsushita N, Hashimoto E, Tokushige K.
    • Journal Title

      Intern. Med.

      Volume: 56 Issue: 5 Pages: 473-480

    • DOI

      10.2169/internalmedicine.56.7626

    • NAID

      130005399415

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Safety and efficacy of long-term tolvaptan therapy for decompensated liver cirrhosis.2016

    • Author(s)
      Kogiso T, Tokushige K, Hashimoto E, Ikarashi Y, Kodama K, Taniai M, Torii N, Shiratori K.
    • Journal Title

      Hepatol Res.

      Volume: 46 Issue: 3

    • DOI

      10.1111/hepr.12547

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Response to tolvaptan and its effect on prognosis in cirrhotic patients with ascites.2016

    • Author(s)
      Kogiso T, Yamamoto K, Kobayashi M, Ikarashi Y, Kodama K, Taniai M, Torii N, Hashimoto E, Tokushige K.
    • Journal Title

      Hepatol Res.

      Volume: - Issue: 9 Pages: 835-844

    • DOI

      10.1111/hepr.12822

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Four cases of type 1 diabetes mellitus showing sharp serum transaminase increases and hepatomegaly due to glycogenic hepatopathy.2016

    • Author(s)
      Ikarashi Y, Kogiso T, Hashimoto E, Yamamoto K, Kodama K, Taniai M, Torii N, Takaike H, Uchigata Y, Tokushige K.
    • Journal Title

      Hepatol Res.

      Volume: なし Issue: 3

    • DOI

      10.1111/hepr.12713

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Successful Treatment of Ascites using a Denver<sup>®</sup> Peritoneovenous Shunt in a Patient with Paroxysmal Nocturnal Hemoglobinuria and Budd-Chiari syndrome2016

    • Author(s)
      Kogiso T, Hashimoto E, Ito T, Hara T, Ikarashi Y, Kodama K, Taniai M, Torii N, Yoshinaga K, Morita S, Takahashi Y, Tanaka J, Sakai S, Yamamoto M, Tokushige K.
    • Journal Title

      Intern. Med.

      Volume: 55 Issue: 20 Pages: 2957-2963

    • DOI

      10.2169/internalmedicine.55.7087

    • NAID

      130005430009

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Mycophenolate mofetil may induce prolonged severe anemia during pegylated-interferon/ribavirin/simeprevir therapy in liver transplant recipients.2015

    • Author(s)
      Kogiso T, Tokushige K, Hashimoto E, Taniai M, Omori A, Kotera Y, Egawa H, Yamamoto M, Shiratori K.
    • Journal Title

      Clin J Gastroenterol.

      Volume: 8 Issue: 3 Pages: 156-61

    • DOI

      10.1007/s12328-015-0570-2

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Daclatasvir/Asunaprevir Therapy Provides High Tolerability and Effectiveness for HCV-Positive Kidney Transplant Recipients.2015

    • Author(s)
      Kogiso T, Hashimoto E, Yamamoto K, Ikarashi Y, Kodama K, Taniai M, Torii N, Tanabe K, Ishida H, Fuchinoue S, Tokushige K.
    • Journal Title

      J Liver: Dis Transplant

      Volume: 4

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] A case report: primary hyperoxaluria complicated with liver cirrhosis.2015

    • Author(s)
      1.Kogiso T, Tokushige K, Hashimoto E, Miyakata C, Taniai M, Torii N, Omori A, Kotera Y, Egawa H, Yamamoto M, Nagata M, Shiratori K.
    • Journal Title

      Hepatol Res.

      Volume: なし Issue: 12 Pages: 1251-5

    • DOI

      10.1111/hepr.12494

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Spontaneous clearance of HCV accompanying hepatitis after liver transplantation.2015

    • Author(s)
      Kogiso T, Hashimoto E, Ikarashi Y, Kodama K, Taniai M, Torii N, Egawa H, Yamamoto M, Tokushige K.
    • Journal Title

      Clin J Gastroenterol.

      Volume: なし Issue: 5 Pages: 323-329

    • DOI

      10.1007/s12328-015-0602-y

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] 非アルコール性脂肪肝炎 (NASH)における性差と年齢の関与; -生活習慣病、脂肪測定、アディポサイトカイン、遺伝子多型を中心に-2014

    • Author(s)
      小木曽智美、橋本悦子、徳重克年、千嶋さやか、児玉和久、戸張真紀、松下典子、谷合麻紀子、鳥居信之、白鳥敬子.
    • Journal Title

      肝臓

      Volume: 55 Pages: 199-205

    • NAID

      130004495334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Journal Article] Efficient induction of apoptosis by wee1 kinase inhibition in hepatocellular carcinoma cells.2014

    • Author(s)
      2.Kogiso T, Nagahara H, Hashimoto E, Ariizumi S, Yamamoto M, Shiratori K.
    • Journal Title

      PLoS One.

      Volume: 24 Issue: 6 Pages: e100495-e100495

    • DOI

      10.1371/journal.pone.0100495

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 当院におけるアルコール性及び非アルコール性脂肪性肝疾患に対する肝移植後経過の検討2017

    • Author(s)
      五十嵐悠一, 小木曽智美, 小林睦季, 児玉和久, 谷合麻紀子, 鳥居信之, 橋本悦子, 江川裕人, 山本雅一
    • Organizer
      第103回日本消化器病学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H04935
  • [Presentation] 腎移植後C型肝炎ウイルスに対するインターフェロンフリー治療の有効性と安全性の検討2016

    • Author(s)
      小木曽智美、橋本悦子、五十嵐悠一、児玉和久、谷合麻紀子、鳥居信之、徳重克年
    • Organizer
      第102回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 肝・腎移植後のC型肝炎治療経過の検討2016

    • Author(s)
      小木曽智美、五十嵐悠一、児玉和久、谷合麻紀子、鳥居信之、橋本悦子、徳重克年、江川裕人、山本雅一
    • Organizer
      第34回日本肝移植研究会
    • Place of Presentation
      旭川
    • Year and Date
      2016-07-07
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] An efficacy and safety of daclatasvir/asunaprevir therapy for HCV-positive kidney transplantation.2016

    • Author(s)
      Kogiso T, Hashimoto E, Kuniko Y, Ikarashi Y, Kodama K, Torii N, Taniai M, Tokushige K.
    • Organizer
      The 25th annual meeting of the Asian Pacific Association for the Study of the Liver (APASL)
    • Place of Presentation
      Tokyo International Convention Center Pamir
    • Year and Date
      2016-02-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] NASH発症・進展に関する遺伝的バックグランドの検討2016

    • Author(s)
      小木曽智美、橋本悦子、徳重克年.
    • Organizer
      第52回日本肝臓学会総会
    • Place of Presentation
      千葉
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] Risk factors of primary biliary cholangitis (PBC) recurrence after liver transplantation in female patients: A Japanese multicenter retrospective study.2016

    • Author(s)
      Kogiso T, Egawa H, Hashimoto E, Tokushige K, Sakisaka S, Teramukai S, Sakabayashi S , Yamamoto M, Umeshita K , Uemoto S.
    • Organizer
      The 67th annual meeting of the American Association for the Study of Liver Diseases (AASLD)
    • Place of Presentation
      Boston
    • Year and Date
      2016-11-11
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] (International Session1 Pathological features of nonalcoholic steatohepatitis(JSH/JSGE))The hostological course of nonalcoholic steatohepatitis:a longitudinal study of sequential liver biopsies2015

    • Author(s)
      Kogiso T, Hashimoto E, Tokushige K.
    • Organizer
      The19th General Meeting of the Japan Society of Hepatology/57th Annual Meeting of the Japanese Society of Gastroenterology (JDDW2015)
    • Place of Presentation
      東京 グランドプリンスホテル新高輪・国際館パミール・グランドプリンスホテル高輪
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 肝硬変に伴う腹水に対するトルバプタン治療の長期経過の検討2015

    • Author(s)
      小木曽智美,徳重克年、橋本悦子、児玉和久、戸張真紀、谷合麻紀子、鳥居信之、白鳥敬子
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本 ホテル日航熊本など
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] Resistance to TGF-beta-induced apoptosis is not associated with the de-differentiation in hepatocellular carcinoma.2015

    • Author(s)
      Kogiso T, Hashimoto E, Kodama K, Ikarashi Y, Torii N, Taniai M, Tokushige K, Shiratori K.
    • Organizer
      American Association for Cancer Research (AACR) 106th Annual Meeting 2015
    • Place of Presentation
      Philadelphia, U.S.A., Pennsylvania Convention Center
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 移植後のC型肝炎ウイルス再感染の経過2015

    • Author(s)
      小木曽智美, 徳重克年, 橋本悦子, 五十嵐悠一, 児玉和久, 谷合麻紀子, 鳥居信之, 白鳥敬子, 江川裕人, 山本雅一
    • Organizer
      第101回日本消化器病学会総会
    • Place of Presentation
      仙台 仙台国際センター
    • Year and Date
      2015-04-23
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] NAFLD及びアルコール性肝障害を基盤にした肝細胞癌の他施設研究ー性差に関してー2015

    • Author(s)
      小木曽智美, 五十嵐悠一, 谷合麻紀子, 鳥居信之, 橋本悦子, 徳重克年
    • Organizer
      第11回消化器病における性差医学・医療研究会
    • Place of Presentation
      旭川 旭川グランドホテル
    • Year and Date
      2015-07-25
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] (パネルディスカッション3 ウイルス肝炎に対する肝移植ー抗ウイルス療法の変遷と術後管理)肝移植後C型肝炎ウイルスの最新治療薬と免疫抑制剤との薬物相互作用2015

    • Author(s)
      小木曽智美,橋本悦子,徳重克年
    • Organizer
      第33回日本肝移植研究会
    • Place of Presentation
      神戸 ホテルオークラ神戸
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] Risk factors for hepatocellular carcinoma recurrence in patients with nonalcoholic and alcoholic fatty liver diseases: A Japanese multicenter survey2015

    • Author(s)
      Kogiso T, Hashimoto E, Hyogo H, Nakajima T, Ono M, Kawaguchi T, Honda K, Eguchi Y, Nozaki Y, Kawanaka M, Imajo K, Sumida Y, Kamada Y, Fujii H, Suzuki Y, and Tokushige K
    • Organizer
      The 66th annual meeting of the American Association for the Study of Liver Diseases (AASLD),
    • Place of Presentation
      San Francisco, U.S.A., Moscone West Convention Center
    • Year and Date
      2015-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 幹細胞マーカー発現から見た非アルコール性脂肪性肝炎の病態の臨床病理学的検討

    • Author(s)
      小木曽智美、谷合麻紀子、橋本悦子.
    • Organizer
      第50回日本肝臓学会総会
    • Place of Presentation
      ホテルニューオータニ (東京都千代田区)
    • Year and Date
      2014-05-29 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] Differential expression of cancer stem cell markers and their clinicopathological features in hepatocellular carcinoma patients with different etiologies.

    • Author(s)
      Kogiso T, Hashimoto E, Kodama K, Tobari M, Matsushita N, Torii N, Taniai M, Tokushige K, Shiratori K.
    • Organizer
      American Association for Cancer Research (AACR)
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 当院における成人急性肝不全に対する生体部分肝移植の検討

    • Author(s)
      小木曽智美、徳重克年、橋本悦子、児玉和久、戸張真紀、谷合麻紀子、鳥居信之、白鳥敬子、江川裕人、山本雅一.
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京国際フォーラム (東京都千代田区)
    • Year and Date
      2014-04-23 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] Early Morning Breakfast Workshop 「Carcinogenesis, Genomics, Pathways and Targets」 Molecular mechanisms underlying the development of hepatocellular carcinoma (HCC)

    • Author(s)
      Kogiso T, Hashimoto E.
    • Organizer
      第4回国際肝癌シンポジウムKYOTO (4th International Kyoto Liver Cancer Symposium (IKLS) )
    • Place of Presentation
      国立京都国際会館 (京都府京都市)
    • Year and Date
      2014-06-07 – 2014-06-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 肝硬変による難治性腹水に対するトルバプタンの有効性およびその効果予測因子に関する検討

    • Author(s)
      小木曽智美、徳重克年、橋本悦子.
    • Organizer
      第18回日本肝臓学会大会、第56回日本消化器病学会大会
    • Place of Presentation
      神戸国際展示場・会議場・ポートピアホテル (兵庫県神戸市)
    • Year and Date
      2014-10-23 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 肝移植後、自然経過でC型肝炎ウイルス消失を来した2症例

    • Author(s)
      小木曽智美、徳重克年、橋本悦子、谷合麻紀子、鳥居信之、児玉和久、白鳥敬子、江川裕人、山本雅一.
    • Organizer
      第32回日本肝移植研究会
    • Place of Presentation
      京王プラザホテル (東京都新宿区)
    • Year and Date
      2014-07-03 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] Cancer stem cell marker expression and their clinicopathological features in NASH patients with hepatocellular carcinoma.

    • Author(s)
      Kogiso T, Taniai M, Hashimoto E.
    • Organizer
      The 25th Annual Meeting of the Japanese Society for Gastroenterological Carcinogenesis.
    • Place of Presentation
      ホテル日航福岡 (福岡県福岡市)
    • Year and Date
      2014-11-13 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-26461024
  • [Presentation] 成人急性肝不全に対する生体部分肝移植の検討

    • Author(s)
      小木曽智美、徳重克年、橋本悦子.
    • Organizer
      第40回日本肝臓学会東部会
    • Place of Presentation
      京王プラザホテル (東京都新宿区)
    • Year and Date
      2014-11-27 – 2014-11-28
    • Data Source
      KAKENHI-PROJECT-26461024
  • 1.  Yamamoto Masakazu (60220498)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 2.  Kogiso Tomomi (10318082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 31 results
  • 3.  TANABE Kazunari (80188359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  YAGISAWA Takashi (80167692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TOKUMOTO Tadahiko (30246540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TOMA Hiroshi (90075549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HAYASHI Naoaki (10075286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  古賀 祥嗣 (30277123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  有泉 俊一 (40277158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  徳重 克年 (60188729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  正田 純一 (90241827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  柳川 徹 (10312852)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  後藤 直宏 (60323854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  磯辺 智範 (70383643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  蕨 栄治 (70396612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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