TOKUSHIGE Katsutoshi 徳重克年

… Alternative Names

Researcher Number	60188729
External Links
Affiliation (Current)	2021: 東京女子医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2020: 東京女子医科大学, 医学部, 教授 2005 – 2007: 東京女子医科大学, 医学部, 講師 2004: Tokyo Women's Medical University, Institute of Gastroenterology, Instructor, 医学部・消化器内科, 助手 2003: 東京女子医科大学, 医学部, 助手 2002: 東京女子医科大学, 医学部, 准講師 1997 – 2000: 東京女子医科大学, 医学部, 助手 1991: 順天堂大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Experimental pathology / Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator HCV / Antisense RNA / IFN / polymorphism / C型肝炎 / TNF / SNP / NASH / DNA ワクチン / アンチセンス RNA … More Except Principal Investigator 脂肪性肝炎 / 肝癌 / 非アルコール性脂肪性肝炎 / 遺伝子改変マウス / somatic mutation / LPS / NASH / 抗DNA抗体 / 全身性エリテマトーデス / 抗体遺伝子可変領域 / クローン性増殖 / クラス転換 / New Zealandマウス / CD5B細胞 / New Zealand マウス / 全身性エリテマト-デス / 免疫グロブリン遺伝子 / ハイブリド-マ / anti-DNA antibodies / systemic lupus erythematosus / immunoglobulin variable region / class-switch / clonal proliferation / New Zealand mice / 女性ホルモン / 転写因子 / 臓器連環 / 性差 / 臓器連関 / クッパー細胞 / 非アルコール性脂肪性肝疾患 / エストラジオール / p62遺伝子欠損マウス / 腸内細菌叢 / エンドトキシン / 腸管バリアー機能 / 遺伝子レスキューマウス / 腸管透過性 / 高カロリー食 / 遺伝子レスキュ－マウス / Kupffer細胞 / 肝星細胞 / 脂肪酸代謝 / ミトコンドリア / 肝発癌 / 遺伝子ノックイン Less

腸内細菌叢の異常と肝癌リスクの増大―新しいNASHモデルによる生体防御機構の解明Ongoing
- Principal Investigator
  
  山本雅一
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Women's Medical University
脂肪酸代謝の異常と肝癌リスクの増大―新しいNASHモデルによる生体防御機構の解明Ongoing
- Principal Investigator
  
  有泉俊一
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Women's Medical University
Pathophysiological mechanism for the high incidence of overeating-induced obesity, NASH and hepatic carcinogenesis in post-menoposal women
- Principal Investigator
  
  Yamamoto Masakazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
Clinical applicdtion of SNP analysis in liver diseasesPrincipal Investigator
- Principal Investigator
  
  TOKUSHIGE Katsutoshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Women's Medical University
The analysis of host factor on the progression in the patients with HCV.Principal Investigator
- Principal Investigator
  
  TOKUSHIGE Katsutoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Women's Medical University
The mechanism of liver cell damage in the patients with HCV and development of ne therap and vaciPrincipal Investigator
- Principal Investigator
  
  TOKUSHIGE Katsutoshi
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Women's Medical University
Origin of class-specific anti-DNA antibodies
- Principal Investigator
  
  HIROSE Sachiko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Juntendo University School of Medicine

All 2020 2018 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Atypical Sarcoidosis Diagnosed by Massive Splenomegaly2020
- Author(s)
  Saito S, Kodama K, Kogiso T, Yamanashi Y, Taniai M, Ariizumi S, Yamamoto M, Tokushige K
- Journal Title
  
  Internal Medicine
  
  Volume: 59 Issue: 5 Pages: 641-648
- DOI
  10.2169/internalmedicine.3646-19
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02884, KAKENHI-PROJECT-18H03197
[Journal Article] Deletion of both p62 and Nrf2 spontaneously leads to development of nonalcoholic steatohepatitis.2018
- Author(s)
  Akiyama K, Warabi E, Okada K, Yanagawa T, Tokushige K, Ariizumi S, Yamamoto M, Shoda J
- Journal Title
  
  Experimental Animals
  
  Volume: 67 Pages: 201-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03197
[Journal Article] Deletion of both p62 and Nrf2 spontaneously leads to development of nonalcoholic steatohepatitis.2018
- Author(s)
  Akiyama K, Warabi E, Okada K, Yanagawa T, Tokushige K, Yamagata K, Ariizumi S, Yamamoto M, Shoda J
- Journal Title
  
  Experimental Animals
  
  Volume: 67 Pages: 201-218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02884
[Journal Article] Deletion of both <i>p62</i> and <i>Nrf2</i> spontaneously results in the development of nonalcoholic steatohepatitis2018
- Author(s)
  AKIYAMA Kentaro、WARABI Eiji、OKADA Kosuke、YANAGAWA Toru、ISHII Tetsuro、KOSE Katsumi、TOKUSHIGE Katsutoshi、ISHIGE Kazunori、MIZOKAMI Yuji、YAMAGATA Kenji、ONIZAWA Kojiro、ARIIZUMI Shun-ichi、YAMAMOTO Masakazu、SHODA Junichi
- Journal Title
  
  Experimental Animals
  
  Volume: - Issue: 2 Pages: 201-218
- DOI
  10.1538/expanim.17-0112
- NAID
  130006733609
- ISSN
  1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19888, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H04917, KAKENHI-PROJECT-15H04935, KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-16J00793, KAKENHI-PROJECT-16K15188, KAKENHI-PROJECT-17K08781
[Journal Article] Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.2018
- Author(s)
  Kawaguchi T, Shima T, Mizuno M, Mitsumoto Y, Umemura A, Kanbara Y, Tanaka S, Sumida Y, Yasui K, Takahashi M, Matsuo K, Itoh Y, Tokushige K, Hashimoto E, Kiyosawa K, Kawaguchi M, Itoh H, Uto H, Komorizono Y, Shirabe K, Takami S, Takamura T, Kawanaka M, Yamada R, Matsuda F, Okanoue T
- Journal Title
  
  PLoS One
  
  Volume: 13
- NAID
  120006398880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04935
[Journal Article] Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis2007
- Author(s)
  Tokushige K., et. al.
- Journal Title
  
  J Hepatol 46
  
  Pages: 1104-1110
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Ethnic, differences genetic analysis in patients with nonalcoholic steatohepatitis2007
- Author(s)
  Tokushige, K., et. al.
- Journal Title
  
  J Hepatol
  
  Pages: 870-871
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Combined pantethihe and probucol therapy for Japanese patients with non-alcoholic Steatohepatitis2007
- Author(s)
  Tokushige, K., et. al.
- Journal Title
  
  Hepatol Res 37
  
  Pages: 872-877
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Influence of TNF- gene polymorphisms in Japanese. patients with NASH and simple Steatosis2007
- Author(s)
  Tokushige, K., et. al.
- Journal Title
  
  J Hepatol 46
  
  Pages: 1104-1110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Possible involvement of cytokine gene polymorphisms in fulminant hepatitis2007
- Author(s)
  Takakura M, Tokushige K., et. al.
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 271-1277
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Ethnic differences of genetic analysis in patients with nonalcoholic steatohepatitis2007
- Author(s)
  Tokushige K., et. al.
- Journal Title
  
  J Hepatol 47
  
  Pages: 870-871
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis2007
- Author(s)
  Tokushige K, et. al.
- Journal Title
  
  J Hepatol 46
  
  Pages: 1104-1110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Combined pantethine and probucol therapy for Japanese patients with non-alcoholic steatohepatitis2007
- Author(s)
  Tokushige K., et. al.
- Journal Title
  
  Hepatol Res 37
  
  Pages: 872-877
- NAID
  10019950420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Possible involvement of cytokine gene polymorphisms in fulminant hepatitis2007
- Author(s)
  Takakura, M., Tokushige, K., et. al.
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 1271-1277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Ethnic differences of genetic analysis in patients with nonalcoholic steatohepatitis2007
- Author(s)
  Tokushige K, et. al.
- Journal Title
  
  J Hepatol 47
  
  Pages: 870-871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Influence of TNF gene polymorphisms in Japanese patients with Nash and simple steatosis.2006
- Author(s)
  Tokushige K, Takakura M, Tsuchiya-Matsushita N, Taniai M, Hashimoto E, Shiratori K
- Journal Title
  
  J Hepatology. (In press)
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] アルコール性肝障害の肝細胞癌発生におけるB型肝炎ウイルス既往感染の影響に関して。2006
- Author(s)
  徳重克年, 橋本悦子, 戸張真紀, 八辻賢, 高倉美保子, 谷合麻紀子, 白鳥敬子
- Journal Title
  
  日本アルコール・薬物医学会雑誌 41
  
  Pages: 120-127
- NAID
  10016687439
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Hyaluronic acid levels can predict severe fibrosis and platelet counts can predict cirrhosis in patients with nonalcoholic fatty liver disease.2006
- Author(s)
  Kaneda H, Hashimoto E, Yatsuji S, Tokushige K, Shiratori K
- Journal Title
  
  J Gastroenterol Hepatol. 21
  
  Pages: 1459-65
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] IFN,Ribavirin併用療法無効例に関する遺伝子多型を含む検討。2006
- Author(s)
  松下典子, 徳重克年, 高倉美保子, 戸張真紀, 八辻賢, 谷合麻紀子他
- Journal Title
  
  肝臓 47
  
  Pages: 290-297
- NAID
  10018070386
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Possible involvement of cytokine gene polymorphisms in fulminant hepatitis.2006
- Author(s)
  Takakura M, Tokushige K, Tsuchiya-Matsusgita N, Hashimoto E, Shiratori K
- Journal Title
  
  J Gastroenterol Hepatol. (In press)
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Clinical significance of soluble TNF receptor in Japanese, patients with non-alcoholic Steatohepatitis2005
- Author(s)
  Tokushige, K., et. al.
- Journal Title
  
  Alcohol clin Exp Res 29
  
  Pages: 298-303
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] A murine model of acute liver injury induced by human monoclonal autoantibody.2005
- Author(s)
  Yamauchi K, Yamaguchi N, Tokushige K. et al.
- Journal Title
  
  Hepatology. 42
  
  Pages: 149-155
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Pediatric nonalcoholic steatohepatitis associated with hypopituitarism.2005
- Author(s)
  Nakajima K, Hashimot E, Tokushige K. et al.
- Journal Title
  
  J Gastroenterol. 40
  
  Pages: 312-315
- NAID
  10015572656
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Clinical significance of soluble TNF receptor in Japanese patients with non-alcoholic steatohepatitis.2005
- Author(s)
  Tokushige K, Hashimoto E, Tuchiya N, et al.
- Journal Title
  
  Alcohol Clin Exp Res. 29
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Diagnosing autoimmune hepatitis in nonalcoholic fatty liver disease : is the international Autommune Hepatitis Group scoring system useful?2005
- Author(s)
  Yatsuji S, Hashimoto E, Tokushige K et al.
- Journal Title
  
  J Gastroenterol. 40
  
  Pages: 1130-1138
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] Liver failure caused by non-alcoholic steatohepatitis in an obese young male.2005
- Author(s)
  Suzuki D, Hahimoto E, Tokushige K. et al.
- Journal Title
  
  J Gastroenterol Hepatol. 20
  
  Pages: 327-329
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] The characteristics and natural history of Japanese patients with nonalcoholic fatty liver disease.2005
- Author(s)
  Hashimoto E, Yatsuji S, Tokushige K, et al.
- Journal Title
  
  Hepatol Res. 33
  
  Pages: 72-76
- NAID
  10016809039
- Data Source
  KAKENHI-PROJECT-17590684
[Journal Article] A novel IgM class autoantibody to hepatocyte-related 190kDa mole in patients with type 1 autoimmune hepatitis2004
- Author(s)
  Yamauchi K, Yamaguchi N, Furukawa T, Tokushige, et al.
- Journal Title
  
  Hepatology 40
  
  Pages: 687-692
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] A novel IgM class autoantibody to hepatocyte-realated 190 kDa mole in patients with type 1 autoimmune hepatitis.2004
- Author(s)
  Yamauchi K, Yamaguchi N, Furukawa T, Takatsu K, Nakanishi T, Sasaki M, Isono E, Tokushige K, Komatsu T, Shiratori K.
- Journal Title
  
  Heptology 40
  
  Pages: 687-692
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Comparison of hepatocellular carcinoma patients with alcoholic liver disease and nonalcoholic steatohepatitis2004
- Author(s)
  Hashimoto E, Taniai M, Kaneko H, Tokushige K, Hasegawa K, Okuda H, Shiratori K
- Journal Title
  
  Alcohol Clin Exp Res 28
  
  Pages: 164-168
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Influence of TNF gene polymorphism in patients with acute and fluorinate hepatitis2004
- Author(s)
  Tsuchiya N, Tokushige K, Yamaguchi N, Hasegawa K, Hashimoto E, Shiratori K
- Journal Title
  
  J. Gastroenterology 39
  
  Pages: 859-866
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Comparison of hepatocellular carcinoma patients with alcoholic liver disease and nonalcoholic steaohepatitis.2004
- Author(s)
  Hashimoto E, Taniai M, Kaneda H, Tokushige K, Hasegawa K, Okuda H, Shirtori K, Takasaki K.
- Journal Title
  
  Alcohol Clin Exp Res 228
  
  Pages: 164-168
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Influence of TNF gene polymorphism in patients with acute and fulminant hepatitis2004
- Author(s)
  Tsuchiya N, Tokushige K, Yamaguchi N, Hasegawa K, Hashimoto E, Shiratori K
- Journal Title
  
  J.Gastroenterology 39
  
  Pages: 859-866
- NAID
  10013613314
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] A novel IgM class autoantibody to hepatocyte-related 190KDa mole in patients with type 1 autoimmune hepatitis2004
- Author(s)
  Yamauchi K, Yamaguchi N, Furukawa T, Tokushige K, et al.
- Journal Title
  
  Hepatology 40
  
  Pages: 687-692
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Influence of TNF gene polymorphism in patients with acute and fulminant hepatitis.2004
- Author(s)
  Tsuchiya N, Tokushige K, Yamaguchi N, Hasegawa K, Hashimoto E, Yamauchi K, Shiratori K.
- Journal Title
  
  J.Gastroenterol. 39
  
  Pages: 859-866
- NAID
  10013613314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Clinical significance of soluble TNF receptors in the patients with non-alcoholic steatohepatitis
- Author(s)
  Tokushige K, Hashimoto E, Tsuchiya N, Kaneda H, Taniai M, Shiratori K
- Journal Title
  
  Alcohol Clin Exp Res In press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Pediatric non-alcoholic steatohepatitis associated with hypopituitarism.
- Author(s)
  Nakajima K, Hashimoto E, Kaneda H, Tokushige K, Shiratori K, Hizuka N, Takano
- Journal Title
  
  J Gastrornterol. (In press)
- NAID
  10015572656
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Clinical significance of soluble TNF receptors in the patients with non-alcoholic steatohepatitis
- Author(s)
  Tokushige K, Hashimoto E, Tsuchiya N, Kaneda H, Taniai M, Shiratori K
- Journal Title
  
  Alcohol Clin Exp Res (In press)
- Data Source
  KAKENHI-PROJECT-14570515
[Journal Article] Clinical significance of soluble TNF receptors in the patients with non-alcoholic steatohepatitis.
- Author(s)
  Tokushige K, Hashimoto E, Tsuchiya N, Kanda H, Taniai M, Shiratori K.
- Journal Title
  
  Alcohol Clin Exp Res. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570515
[Presentation] Influence of adiponectin gene polymorphisms in patients with nonalocoholic fatty liver disease2007
- Author(s)
  Tokushige K
- Organizer
  第58回アメリカ肝臓学会
- Place of Presentation
  米国ボストン
- Year and Date
  2007-11-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590684
[Presentation] Influence of adiponectin gene polymorphisms in patients with nonalcoholic fatty liver disease2007
- Author(s)
  Tokushige K
- Organizer
  第58回アメリカ肝臓学会
- Place of Presentation
  米国ボストン
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-17590684
[Presentation] Influence, of adiponectin gene polymorphisms in patients with nonalco holic fatty liver disease2006
- Author(s)
  Tokushige, K
- Organizer
  第68回アメリカ肝臓学会
- Place of Presentation
  米国ボストン
- Year and Date
  2006-11-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590684
[Presentation] Discrimination between NASH and fatty Liver by TNF gene polymorphisms2006
- Author(s)
  Tokushige, K
- Organizer
  第57回アメリカ肝臓学会
- Place of Presentation
  米国ボストン
- Year and Date
  2006-11-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590684

1. Yamamoto Masakazu (60220498)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. 有泉俊一 (40277158)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. 正田純一 (90241827)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. 蕨栄治 (70396612)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. 柳川徹 (10312852)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. HIROSE Sachiko (00127127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. WAKIYA Midori (00220848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UEDA Genjiroh (90203439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 橋本悦子 (40130273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 後藤直宏 (60323854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 磯辺智範 (70383643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岡田浩介 (80757526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 石井功

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 溝上裕士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOKUSHIGE Katsutoshi 徳重 克年

徳重 克年 トクシゲ カツトシ

Research Projects

Research Products

Co-Researchers

腸内細菌叢の異常と肝癌リスクの増大―新しいNASHモデルによる生体防御機構の解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脂肪酸代謝の異常と肝癌リスクの増大―新しいNASHモデルによる生体防御機構の解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological mechanism for the high incidence of overeating-induced obesity, NASH and hepatic carcinogenesis in post-menoposal women

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical applicdtion of SNP analysis in liver diseasesPrincipal Investigator

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The analysis of host factor on the progression in the patients with HCV.Principal Investigator

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The mechanism of liver cell damage in the patients with HCV and development of ne therap and vaciPrincipal Investigator

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Origin of class-specific anti-DNA antibodies

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[Journal Article] Atypical Sarcoidosis Diagnosed by Massive Splenomegaly2020

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[Journal Article] Deletion of both p62 and Nrf2 spontaneously leads to development of nonalcoholic steatohepatitis.2018

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[Journal Article] Deletion of both p62 and Nrf2 spontaneously leads to development of nonalcoholic steatohepatitis.2018

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[Journal Article] Deletion of both <i>p62</i> and <i>Nrf2</i> spontaneously results in the development of nonalcoholic steatohepatitis2018

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[Journal Article] Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.2018

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[Journal Article] Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis2007

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TOKUSHIGE Katsutoshi 徳重克年

徳重克年トクシゲカツトシ