SHIMAZAKI Kuniko 島崎久仁子

… Alternative Names

島崎久仁子シマザキクニコ

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Researcher Number	40142153
Other IDs
External Links
Affiliation (Current)	2025: 自治医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 自治医科大学, 医学部, 非常勤講師 2015: 自治医科大学, 脳神経外科, 非常勤講師 2013 – 2015: 自治医科大学, 医学部, 非常勤講師 2001 – 2006: 自治医科大学, 医学部, 講師 1998 – 1999: 自治医科大学, 医学部, 講師 … More 1995 – 1996: 自治医科大学, 医学部, 講師 1990: 東京都神経研, 病態神経生理, 研究員 1990: 東京都神経科学総合研究所, 病態神経生理学研究室, 研究員 1988 – 1989: 東京都神経科学総合研究所, 研究員 1987: Tokyo Metropolitan Institute for Neuroscinces, 病態生理, 研究員 Less
Review Section/Research Field	Principal Investigator Neuroscience in general / Neurochemistry/Neuropharmacology Except Principal Investigator Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery / Neurophysiology and muscle physiology / Experimental pathology
Keywords	Principal Investigator apoptosis / Bcl-2 / ischemia / hippocampus / gerbil / スナネズミ / bcl-2 / 海馬 / CA1 / delayed neuronal death … More / tolerance to ischemia / AAV vector / gene therapy / adeno-associated virus / adeno-associated virus vecoor / brain ischermia / GLT-1 / 遅発性神経細胞死 / 遅発性脳神経細胞死 / アデノ随伴ウイルスベクター / 脳虚血 / アポトーシス / delayd neuronal death / 神経細胞死 / 虚血 / CAl / bc1-2 … More Except Principal Investigator JSTX / IP_4 / slice / hippocampus / calcium / cerebral ischemia / てんかん / 迷走神経刺激 / 海馬 / グルタミン酸レセプター / クモ毒素 / グルタミン酸 / 脳虚血 / resistance / 脳深部刺激 / 大脳皮質 / 視床 / ニューロモデュレーション / てんかん外科 / 多点脳表脳波 / 大脳皮質ネットワーク / 記憶 / 神経ネットワーク / 大脳電気刺激 / Brain Ischemia / Hippocampus / Cerebellum / GTP Binding Protein / Spider Toxin / Glutamic acid / Glutamate Receptor / アフィニティーカラム / 標識化クモ毒素 / 1-ナフチルアセチルスペルミン / アビジン・ビオチン / 小脳 / GTP結合蛋白 / グルタミン酸レセプタ- / spider toxin Joro spider toxin / synaptic transmission / glutamate receptor / glutamate / NMA / スライス標本 / JSTX海馬 / クモ毒 / GlutamateB / NSTX / シナプス伝達 / epilepsy / EL mouse / Zn^<2+> / Ca^<2+> / GluR2 / developing gerbil / ミニブタ / AAVベクター / てんかん遺伝子治療 / ELマウス / 遺伝子治療 Less

Elucidation of the Ascending Regulatory Mechanisms of the Cerebral Cortex via the Thalamus for Clinical Applications
- Principal Investigator
  
  川合謙介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Jichi Medical University
Multi-scale investigation of cerebral anatomo-functional changes induced by long-term electrical stimulation and surgical intervention
- Principal Investigator
  
  Kawai Kensuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Jichi Medical University
Gene therapy for epilepsy by intravascular administration of Adeno-associated virus
- Principal Investigator
  
  OGURO KEIJI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Jichi Medical University
Cyte-physiological study of abnormal Ca^<2+> metabolism in ischemic and epileptic neuronal death
- Principal Investigator
  
  OGURO Keiji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Jichi Medical University
Cyte-physiological study of abnormal Ca^<2+> metabolism in delayed neuronal death
- Principal Investigator
  
  OGURO Keiji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Jichi Medical School
The cellular mechanism of ischemic tolerance in hippocampusPrincipal Investigator
- Principal Investigator
  
  SHIMAZAKI Kuniko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Jichi Medical School
ISCHEMIC TOLERANCE DEPRESSED INIRACELLULAR CALCIUM ELEVATION IN GERBILHIPPOCAMPUSPrincipal Investigator
- Principal Investigator
  
  SHIMAZAKI Kuniko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Jichi Medical School
The acquisition of ischemic tolerance in gerbil hippocampus.Principal Investigator
- Principal Investigator
  
  SHIMAZAKI Kuniko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Jichi Medical School
Identification of the Glutamate Receptor and its Application for the Research in Neurological Diseases
- Principal Investigator
  
  KAWAI Nobufumi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Tokyo Metropolitan Institute for Neurosciences
Idendification of the glutamate receptor and analysis of ionchannel dynamics
- Principal Investigator
  
  KAWAI Nobufumi
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Tokyo Metropolitan Institute for Neurosciences

All 2015 2014 2013 2005 2004 Other

All Journal Article Presentation Book

[Book] イオンチャンネルを共有する受容体.グルタミン酸 in生物薬科学実験講座-情報伝達物質[I]受容体-(石橋貞彦,市川厚,堅田利明編集)(廣川書店)2005
- Author(s)
  島崎久仁子, 川合述史
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Book] イオンチャネルを共有する受容体.グルタミン酸.In:生物薬科学実験講座- 情報伝達物質 [I]受容体-(石橋貞彦, 市川厚, 堅田利明編)2005
- Author(s)
  島崎久仁子, 川合述史
- Publisher
  廣川書店、東京
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Electroconvulsive seizures enhance autophagy signaling in rat hippocampus2014
- Author(s)
  Otabe H, Nibuya M, Shimazaki K, Toda H, Suzuki G, Nomura S, Shimizu K
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry
  
  Volume: 50 Pages: 37-43
- DOI
  10.1016/j.pnpbp.2013.11.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300089, KAKENHI-PROJECT-25460501
[Journal Article] Systemic delivery of tyrosine-mutant AAV vectors results in robust transduction of neurons in adult mice.2013
- Author(s)
  Iida A, Takino N, Miyauchi H, Shimazaki K, Muramatsu S
- Journal Title
  
  Bio Med Res Int
  
  Volume: 2013 Pages: 974819-974819
- DOI
  10.1155/2013/974819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590473, KAKENHI-PUBLICLY-25110729, KAKENHI-PROJECT-25460501
[Journal Article] Ischemic tolerance with 3-nitropionic acid induces the over expression of Bcl-2 and Bcl-x_L but lacking for HSP70 and plasma membrane Ca_<2+>-ATPase type12005
- Author(s)
  Kato K, Shimazaki K, Kamiya T, Amemiya S, Inaba T, Oguro K, Katayama Y
- Journal Title
  
  Life Sci (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591543
[Journal Article] Specific and Efficient Transduction of Cochlear Inner Hair Cells with Recombinant Adeno-Associated Virus Type 3 Vector.2005
- Author(s)
  Liu Y, Okada, Sheykholeslami K, Shimazaki K, Nomoto T, Muramatsu S, Kanazawa T, Takeuchi K, Ajalli R, Mizukami H, Kume A, Ichimura K, Ozawa K
- Journal Title
  
  Mol Ther. 12
  
  Pages: 725-733
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Differential effects of sublethal ischemia and chemical preconditioning with 3-nitropropionic acid on protein expression in gerbil hippocampus.2005
- Author(s)
  Kato K, Shimazaki K, Kamiya T, Amemiya S, Inaba T, Oguro K, Katayama Y
- Journal Title
  
  Life Sciences 77
  
  Pages: 2867-2878
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Large-scale production of recombinant viruses by use of a large culture vessel with active gassing.2005
- Author(s)
  Okada T, Nomoto T,, Yoshioka T, Nonaka-Sarukawa M, Ito T, Ogura T, Iwata-Okada, M, Uchibori R, Shimazaki K, Kume A, Ozawa K
- Journal Title
  
  Hum Gene Ther 16
  
  Pages: 1212-1218
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Ischemic tolerance with 3-nitropionic acid induces the over expression of Bcl-2 and Bcl-_<XL> but lacking for HSP70 and plasma membrane Ca^<2+>-ATPase type 1.2005
- Author(s)
  Kato K, Shimazaki K, Kamiya T, Amemiya S, Inaba T, Oguro K, Katayama Y.
- Journal Title
  
  Life Science (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591543
[Journal Article] Specific and efficient transduction of cochlear inner hair cells with recombinant adeno-associated virus type3 vector2005
- Author(s)
  Liu Y, Okada T, Sheykholeslami K, Shimazaki K, Nomoto T, Muramatsu S, Kanazawa T, Takeuchi K, Ajalli R, Mizukami H, Kume A, Ichimura K, Ozawa K
- Journal Title
  
  Mol Ther 12
  
  Pages: 725-733
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Anti-apoptotic and neuroprotective effects of edaravone following transient global ischemia in rats2005
- Author(s)
  Amemiya S, Kamiya T, Nito C, Inaba T, Kato K, Ueda M, Shimazaki K, Katayama Y
- Journal Title
  
  Eur J Pharmacol 516
  
  Pages: 125-130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Large-scale production of recombinant viruses by use of a large culture vessel with active gassing2005
- Author(s)
  Okada T, Nomoto T, Yoshioka T, Nonaka-Sarukawa M, Ito T, Ogura T, Iwata-Okada M, Uchibori R, Shimazaki K, Mizukami H, Kume A, Ozawa K.
- Journal Title
  
  Hum Gene Ther 16
  
  Pages: 1212-1218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Differential effects of sublethal ischemia and chemical preconditioning with 3-nitropropionic acid on protein expression in gerbil hippocampus.2005
- Author(s)
  Kato K, Shimazaki K, Kamiya T, Amemiya S, Inaba T, Oguro K, Katayama Y
- Journal Title
  
  Life Science 77
  
  Pages: 2867-2878
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats.2005
- Author(s)
  Amemiya S, Kamiya T, Nito C, Inaba T, Kato K, Ueda M, Shimazaki K, Katayama Y
- Journal Title
  
  Eur J Pharmacol 516
  
  Pages: 125-130
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Differential effects of sublethal ischemia and chemical preconditioning 3-nitropropionic acid on protein expression in gerbil hippocampus2005
- Author(s)
  Kato K, Shimazaki K, Kamiya T, Amemiya S, Inaba T, Oguro K, Katayama Y.
- Journal Title
  
  Life Sciences 77
  
  Pages: 2867-2878
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Anti-apoptotic and neuroprotective effects of edaravone following transient global ischemia in rats2005
- Author(s)
  Amemiya S, Kamiya T, Nito C, Inaba T, Kato K, Ueda M, Shimazaki K, Katayama Y.
- Journal Title
  
  Eur J Pharmacol 516
  
  Pages: 125-130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Specific and efficient transduction of cochlear inner hair cells with recombinant adeno-associated virus type3 vector2005
- Author(s)
  Liu Y, Okada T, Sheykholeslami K, Shimazaki K, Nomoto T, Muramatsu S, Kanazawa T, Takeuchi K, Ajalli R, Mizukami H, Kume A, Ichimura K, Ozawa K.
- Journal Title
  
  Mol Ther 12
  
  Pages: 725-733
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Large-scale production of recombinant viruses by use of a large culture vessel with active gassing.2005
- Author(s)
  Okada T, Nomoto T, Yoshioka T, Nonaka-Sarukawa M, Ito T, Ogura T, Iwata-Okada M, Uchibori R, Shimazaki K, Mizukami H, Kume A, Ozawa K
- Journal Title
  
  Hum Gene Ther 16
  
  Pages: 1212-1218
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591527
[Journal Article] Ischemic preconditioning decreases intracellular zinc accumulation induced by oxygen-glucose deprivation in gerbil hippocampal CA1 neurons2004
- Author(s)
  Miyawaki T, Yokota H, Oguro K, Yokota H, Kato K, Shimazaki K.
- Journal Title
  
  Neurosci.Letter 362
  
  Pages: 216-219
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591543
[Journal Article] Upregulation of GluR2 decreases intracellular Ca^<2+> following ischemia in developing gerbils2004
- Author(s)
  Oguro K, Miyawaki T, Yokota H, Kato M, Watanabe M, Shimazaki K, et al.
- Journal Title
  
  Neurosci.Letter 364
  
  Pages: 101-105
- Data Source
  KAKENHI-PROJECT-15591543
[Journal Article] Upregulation of GluR2 decreases intracellular Ca^<2+> following ischemia in developing gerbils2004
- Author(s)
  Oguro K, Miyawaki T, Yokota H, Kato, M, Watanabe M, Shimazaki K, et al.
- Journal Title
  
  Neurosci.Letter 364
  
  Pages: 101-105
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591543
[Journal Article] Ischemic preconditioning decreases oxgen-glucose deprivation induced intracellular zink accumulation in gerbil hippocampal CA1 neurons.2004
- Author(s)
  Miyawaki T, Yokota H, Oguro K, Kato K, Shimazaki K.
- Journal Title
  
  Neurosci Letters 362
  
  Pages: 216-219
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591543
[Journal Article] Upregulation of GluR2 decreases intracellular Ca2+ following ischemia in developing gerbils.2004
- Author(s)
  Oguro K, Miyawaki T, Hokota H, Kato K, Kamiya T, Katayama Y, Fukaya M, Watanabe M, Shimazaki K.
- Journal Title
  
  Neurosci Letters 364
  
  Pages: 101-105
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591543
[Presentation] ELマウスにおける血管内投与型アデノ随伴ウイルス(AAV)ベクターによるてんかんの遺伝子治療2015
- Author(s)
  小黒恵司、島崎久仁子、横田英典、アリフ・ダハ、村島善也、村松慎一、渡辺英寿
- Organizer
  第49回日本てんかん学会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25460501
[Presentation] ELマウスにおけるてんかん発作時および間欠期脳血流の検討
- Author(s)
  小黒恵司、島崎久仁子、横田英典、村島善也、間賀田泰寛、渡辺英寿
- Organizer
  第48回日本てんかん学会
- Place of Presentation
  東京
- Year and Date
  2014-10-02 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25460501

1. OGURO KEIJI (90231232)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. MIWA Akikio (60142155)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YOKOTA Hidenori (90254929)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. WATANABE Eiju (50150272)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. KAWAI Nobufumi (00073065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Kawai Kensuke (70260924)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 石下洋平 (30835632)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 中嶋剛 (60625995)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 國井尚人 (80713940)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 高橋宏知 (90361518)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 大谷啓介 (90790676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 大貫良幸 (90835993)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. MURAMATSU Shinichi (10239543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. YOSHIOKA Masanori (30012652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HAGIWARA Kennichi (40192265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAJIMA Terumi (50012597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 佐原資謹 (40206008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 手塚正幸 (40721311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 佐藤信 (80742345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 井林賢志 (90911892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SAITO Mitsuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. PAN-HOU Hidemitsu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SUZUKI Go

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMAZAKI Kuniko 島崎 久仁子

島崎 久仁子 シマザキ クニコ

Research Projects

Research Products

Co-Researchers

Elucidation of the Ascending Regulatory Mechanisms of the Cerebral Cortex via the Thalamus for Clinical Applications

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multi-scale investigation of cerebral anatomo-functional changes induced by long-term electrical stimulation and surgical intervention

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Gene therapy for epilepsy by intravascular administration of Adeno-associated virus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cyte-physiological study of abnormal Ca^<2+> metabolism in ischemic and epileptic neuronal death

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cyte-physiological study of abnormal Ca^<2+> metabolism in delayed neuronal death

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The cellular mechanism of ischemic tolerance in hippocampusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ISCHEMIC TOLERANCE DEPRESSED INIRACELLULAR CALCIUM ELEVATION IN GERBILHIPPOCAMPUSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The acquisition of ischemic tolerance in gerbil hippocampus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of the Glutamate Receptor and its Application for the Research in Neurological Diseases

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Idendification of the glutamate receptor and analysis of ionchannel dynamics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] イオンチャンネルを共有する受容体.グルタミン酸 in生物薬科学実験講座-情報伝達物質[I]受容体-(石橋貞彦,市川 厚,堅田利明編集)(廣川書店)2005

Author(s)

Description

Data Source

[Book] イオンチャネルを共有する受容体.グルタミン酸.In:生物薬科学実験講座- 情報伝達物質 [I]受容体-(石橋貞彦, 市川厚, 堅田利明 編)2005

Author(s)

Publisher

Data Source

[Journal Article] Electroconvulsive seizures enhance autophagy signaling in rat hippocampus2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systemic delivery of tyrosine-mutant AAV vectors results in robust transduction of neurons in adult mice.2013

Author(s)

Journal Title

SHIMAZAKI Kuniko 島崎久仁子

島崎久仁子シマザキクニコ

[Book] イオンチャンネルを共有する受容体.グルタミン酸 in生物薬科学実験講座-情報伝達物質[I]受容体-(石橋貞彦,市川厚,堅田利明編集)(廣川書店)2005

[Book] イオンチャネルを共有する受容体.グルタミン酸.In:生物薬科学実験講座- 情報伝達物質 [I]受容体-(石橋貞彦, 市川厚, 堅田利明編)2005