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shiozawa shunichi  塩沢 俊一

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Shiozawa Shunichi  塩沢 俊一

SHIOZAWA Shunichi  塩沢 俊一

塩澤 俊一  シオザワ シュンイチ

SHIOZAWA Shuninchi  塩沢 俊一

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Researcher Number 40154166
Other IDs
External Links
Affiliation (Current) 2025: 神戸大学, 保健学研究科, 名誉教授
2025: 株式会社膠原病研究所, 研究部, 研究所長
Affiliation (based on the past Project Information) *help 2015: 九州大学, 大学病院, 学術研究員(特任教授)
2013 – 2014: 九州大学, 大学病院, 教授
1995 – 2005: 神戸大学, 医学部, 教授
1996 – 1997: 神戸大学, 医学部・保健学科, 教授
1993: 神戸大学, 医学部, 講師
1987 – 1991: 神戸大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
内科学一般 / Biological Sciences / Immunology / Legal medicine / 睡眠科学 / 膠原病・アレルギー・感染症内科学
Except Principal Investigator
Experimental pathology
Keywords
Principal Investigator
慢性関節リウマチ / 疾患遺伝子 / rheumatoid arthritis / disease gene / microsatellite marker / Dbl / DR3 / death receptor 3(DR3) / genetic predisposition / 遺伝素因 … More / disease susceptibility gene / genome-wide search / 関節リウマチ / 関節破壊 / death receptor 3 (DR3) / rheumatoid arthritis (RA) / 遺伝解析 / Ang-1 / DR3,death receptor 3 / 内科 / テクノバイオロジー / 免疫学 / 遺伝子 / 遺伝学 / 関節リウマチ rheumatoid arthritis(RA) / アポトーシス apoptosis / Db1 proto-oncogene / rheumatoid arthritis disease gene / 遺伝 / wee 1 kinase / c-fos / sib-pair analysis / 慢性関節リュウマチ / 同胞対検索法 / マイクロサテライトマーカー / rheumatoid or thritis / Microsatellite Incfear / Phemiated Anthtis / Disease Seaceptivcity Gene / Geneme-Crcle Search / 重層化 / 増殖 / 滑膜表層細胞 / Factor / Growth / Epidermal / 滑膜表層A型・B型細胞 / EGF(Epidermal growth factor) / ラメルテオン / メラトニン作動薬 / 睡眠障害 / 日常生活動作 / 疾患活動性 / 概日リズム / quality of sleep / 睡眠の質 / biological DMARDs / sleep / 生物学的製剤 / 睡眠 / 免疫応答系 / 遷延感作実験 / シミュレーション / 膠原病 / PCR / 同柤遺伝子 / サイトカイン / 精神障害 / インターフェロンα / 全身性エリテマトーデス / コラ-ゲン / 滑膜 / 骨吸収 / 遺伝子発現 / cーfos / トランスフェクション / トランスジェニックマウス / 滑膜間葉系細胞 / cーfos遺伝子 / 滑膜細胞 / インタ-フェロンα … More
Except Principal Investigator
Metastasis / Cancer invasion / Tissue destruction / Matrix metalloproteinase / Transgenic mice / ECM degradation / ノックアウトマウス / トランスジェニックマウス / 膜型MMP / ゼラチナーゼA / 転移 / 癌細胞浸潤 / 組織破壊 / 遺伝子導入マウス / 細胞外マトリックス分解 / マトリックスメタロプロテアーゼ Less
  • Research Projects

    (15 results)
  • Research Products

    (62 results)
  • Co-Researchers

    (20 People)
  •  Study on the relationship between arthritis and the quality of sleepPrincipal Investigator

    • Principal Investigator
      Shiozawa Shunichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      睡眠科学
    • Research Institution
      Kyushu University
  •  膠原病発症における抗原による遷延感作機構とそのシステム制御の研究Principal Investigator

    • Principal Investigator
      塩沢 俊一
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kobe University
  •  慢性関節リウマチの多因子遺伝に関わる疾患遺伝子の同定Principal Investigator

    • Principal Investigator
      塩沢 俊一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Studies on the causative disease gene in autoimmunity and rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      SHIOZAWA Shunichi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Studies on the Disease Genes of Rheumatoid Arthritis and its Contribution to the Pathogenesis of Rheumatoid ArthritisPrincipal Investigator

    • Principal Investigator
      SHIOZAWA Shunichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Immunology
    • Research Institution
      Kobe University
  •  Studies on the mechanism how chronic inflammation prolongs in rheumatoid arthritis.Principal Investigator

    • Principal Investigator
      SHIOZAWA Shunichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Kobe University
  •  Analyzes on ECM metabolism in transgenic and knockout mice

    • Principal Investigator
      OKADA Yasunori
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Experimental pathology
    • Research Institution
      School of Medicine, Keio University
      Kanazawa University
  •  GENOME-WIDE SEARCH FOR THE DISEASE SUSCEPTIBILITY GENE OF RHEUMATOID ARTHRITISPrincipal Investigator

    • Principal Investigator
      SHIOZAWA Shunichi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      KOBE UNIVERSITY
  •  マイクロサテライトマーカーを用いた慢性関節リチウムの疾患感受性全遺伝子の同定Principal Investigator

    • Principal Investigator
      塩澤 俊一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Kobe University
  •  全身性エリテマトーデスの精神障害の原因としてインターフェロンαの同定とその作用Principal Investigator

    • Principal Investigator
      塩澤 俊一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kobe University
  •  慢性関節リウマチの関節破壊に及ぼすcーfos遺伝子発現の病因及び治療に関する研究Principal Investigator

    • Principal Investigator
      塩澤 俊一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kobe University
  •  cーfos遺伝子発現の慢性関節リウマチの関節破壊,リウマチ因子産生への病因的関与Principal Investigator

    • Principal Investigator
      塩澤 俊一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kobe University
  •  慢性関節リウマチの遷延化に及ぼすインタ-フェロンα低値の病理病態学的研究Principal Investigator

    • Principal Investigator
      塩澤 俊一
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kobe University
  •  慢性関節リウマチの発症における滑膜表層細胞の病因的意味についてPrincipal Investigator

    • Principal Investigator
      塩澤 俊一
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kobe University
  •  Epidermal growth factorの慢性関節リウマチ滑膜増殖への作用-その増殖因子活性および骨吸収活性の病因的意味について-Principal Investigator

    • Principal Investigator
      塩澤 俊一
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kobe University

All 2016 2015 2014 2013 2006 2005 2004 2003 2002 2001 2000 Other

All Journal Article Presentation Book

  • [Book] 膠原病学、改訂第6版2015

    • Author(s)
      塩沢俊一著(単著)
    • Total Pages
      688
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Book] 膠原病学 第6版2015

    • Author(s)
      塩沢俊一
    • Total Pages
      620
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Book] Methods in Molecular Biology vol 11422014

    • Author(s)
      Shiozawa S, eds.
    • Total Pages
      204
    • Publisher
      Springer Humana Press
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Book] Arthritis Research: Methods in Molecular Biology Vol.11422014

    • Author(s)
      Shiozawa S, eds
    • Total Pages
      204
    • Publisher
      Springer Humana Press
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Book] 永井書店2013

    • Author(s)
      塩沢俊一他編
    • Total Pages
      269
    • Publisher
      リウマチ病セミナー
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Book] 膠原病学2013

    • Author(s)
      塩沢俊一著
    • Total Pages
      660
    • Publisher
      丸善出版
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Book] 器官病理学2013

    • Author(s)
      塩沢俊一(分担執筆)
    • Total Pages
      1018
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Book] 「内科疾患診療マニュアル」成人病発症スティル病(富野康日出編)2005

    • Author(s)
      塩沢俊一
    • Total Pages
      700
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-17659301
  • [Book] 「内科疾患診療マニュアル」HLA-B27関連関節炎(富野康日出編)2005

    • Author(s)
      塩沢俊一
    • Total Pages
      352
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-17659301
  • [Book] 日本臨床63巻増刊号、関節リウマチの成因と病態生理、DR3遺伝子変異2005

    • Author(s)
      塩沢俊一
    • Total Pages
      5
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-17659301
  • [Book] 膠原病学2005

    • Author(s)
      塩沢俊一
    • Total Pages
      632
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-17659301
  • [Book] わかりやすい膠原病学2004

    • Author(s)
      塩澤俊一
    • Total Pages
      260
    • Publisher
      丸善株式会社
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] MMP-3 as a predictor for structural remission in RA patients treated with MTX monotherapy.2016

    • Author(s)
      Shiozawa K, Yamane T et al. Shiozawa S(Last author)
    • Journal Title

      Arthritis Res Ther

      Volume: 18 Issue: 1 Pages: 1-9

    • DOI

      10.1186/s13075-016-0948-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] Selective activator protein-1 inhibitor T-5224 prevents lymph node metastasis in an oral cancer model.2016

    • Author(s)
      Kamide D et al. Shiozawa S (Last 2nd author)
    • Journal Title

      Cancer Sci

      Volume: 107 Issue: 5 Pages: 666-673

    • DOI

      10.1111/cas.12914

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] The impact of c-Fos/Activator protein-1 inhibition on allogeneic pancreatic islet transplantation.2015

    • Author(s)
      Yoshida T, Yamashita K, Watanabe M, Koshizuka Y, Kuraya D, Ogura M, Asahi Y, Ono H, Emoto S, Mizukami T, Kobayashi N, Shibasaki S, Tomaru U, Kamachi H, Matsushita M, Shiozawa S, Hirono S, Todo S.
    • Journal Title

      Am J Transplantation

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent.2015

    • Author(s)
      Verheul MK et al. Shiozawa S (Last author)
    • Journal Title

      Rheumatology

      Volume: 54 Issue: 10 Pages: 1930-1932

    • DOI

      10.1093/rheumatology/kev250

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] T-5224, a selective inhibitor of c-Fos activator protein-1, improves survival by inhibiting serum high mobility group box-1 in lethal lipopolysaccharide-induced acute kidney injury model.2015

    • Author(s)
      Ishida M et al. Shiozawa S (Last 2nd author)
    • Journal Title

      J Intensive Care

      Volume: 3 Issue: 1

    • DOI

      10.1186/s40560-015-0115-2

    • NAID

      120005693960

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent.2015

    • Author(s)
      Verheul MK, Shiozawa K, Levarht EWN, Huizinga TWJ, Toes REM, Trouw LA, Shiozawa S.
    • Journal Title

      Rheumatology

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] The Impact of c-Fos/Activator Protein-1 Inhibition on Allogeneic Pancreatic Islet Transplantation.2015

    • Author(s)
      Yoshida T, Yamashita K, Watanabe M, Koshizuka Y, Kuraya D, Ogura M, Asahi Y, Ono H, Emoto S, Mizukami T, Kobayashi N, Shibasaki S, Tomaru U, Kamachi H, Matsushita M, Shiozawa S, Hirono S, Todo S.
    • Journal Title

      Am J Transplant.

      Volume: 15(10) Issue: 10 Pages: 2565-2575

    • DOI

      10.1111/ajt.13338

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460489, KAKENHI-PROJECT-25461181, KAKENHI-PROJECT-25515003
  • [Journal Article] Induction of de novo autoimmune disease in normal mice upon repeated immunization with antigen.2014

    • Author(s)
      Tsumiyama K, Shiozawa S.
    • Journal Title

      Methods Mol Biol

      Volume: 1142 Pages: 85-90

    • DOI

      10.1007/978-1-4939-0404-4_10

    • ISBN
      9781493904037, 9781493904044
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] In vivo cell transfer assay to detect autoreactive T cell subsets.2014

    • Author(s)
      Miyazaki Y, Shiozawa S.
    • Journal Title

      Methods Mol Biol

      Volume: 1142 Pages: 49-53

    • DOI

      10.1007/978-1-4939-0404-4_6

    • ISBN
      9781493904037, 9781493904044
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] Studies on the T cell receptor (TCR) revision of autoantibody-inducing CD4 T (aiCD4 T) cell.2014

    • Author(s)
      Shiozawa S, Uto K.
    • Journal Title

      Methods Mol Biol

      Volume: 1142 Pages: 65-73

    • DOI

      10.1007/978-1-4939-0404-4_8

    • ISBN
      9781493904037, 9781493904044
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] Self-Organized Criticality Theory and the Expansion of PD-1-Positive Effector CD4 T Cells: Search for Autoantibody-Inducing CD4 T Cells.2013

    • Author(s)
      Miyazaki Y, Tsumiyama K, Yamane T, Ito M, Shiozawa S
    • Journal Title

      Front Immunol

      Volume: 4 Pages: 87-87

    • DOI

      10.3389/fimmu.2013.00087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591388, KAKENHI-PROJECT-25515003
  • [Journal Article] TNF-alpha modulates expression of the circadian clock gene Per2 in rheumatoid synovial cells.2013

    • Author(s)
      Yoshida K, Hashiramoto A, Okano T, Yamane T, Shibanuma N, Shiozawa S.
    • Journal Title

      Scand J Rheumatol

      Volume: 42 Issue: 4 Pages: 276-280

    • DOI

      10.3109/03009742.2013.765031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] Keratinocyte stem cells but not melanocyte stem cells are the primary target for radiation-induced hair graying.2013

    • Author(s)
      Aoki H
    • Journal Title

      J Invest Dermatol

      Volume: 155 Pages: 600-10

    • DOI

      10.1172/jci63572

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590239, KAKENHI-PROJECT-24390096, KAKENHI-PROJECT-24659675, KAKENHI-PROJECT-24880023, KAKENHI-PROJECT-25515003, KAKENHI-PUBLICLY-23130508
  • [Journal Article] IFN-γ-producing effector CD8 T lymphocytes cause immune glomerular injury by recognizing antigen presented as immune complex on target tissue.2013

    • Author(s)
      Tsumiyama K, A. Hashiramoto, M. Takimoto, S. Tsuji-Kawahara, M. Miyazawa, and S. Shiozawa
    • Journal Title

      The Journal of Immunology

      Volume: 191 Issue: 1 Pages: 91-96

    • DOI

      10.4049/jimmunol.1203217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390116, KAKENHI-PROJECT-25460507, KAKENHI-PROJECT-25515003
  • [Journal Article] Shorter disease duration in important for tocilizumab to achieve Boolean2013

    • Author(s)
      Kawasaki Y, Hashiramoto A, Okano T, Sakai Y, Yamane T, Shiozawa K, Shiozawa S, Hashiramoto A.
    • Journal Title

      Mod Rheumatol

      Volume: 23 Pages: 192-197

    • DOI

      10.1007/s10165-012-0822-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] Mixed connective tissue disease (MCTD) is distinct from SLE: study of MICA and HLA gene2013

    • Author(s)
      Yoshida K, Inoue H, Komai K, Yamane T, Hashiramoto A, Shiozawa K, Shiozawa S.
    • Journal Title

      Tissue Antigens

      Volume: 81 Issue: 1 Pages: 44-45

    • DOI

      10.1111/tan.12027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Journal Article] Discovery of nonpeptidic small-molecule AP-1 inhibitors : Lead hopping based on 3D pharmacophore model.2006

    • Author(s)
      Tsuchida K, Chaki H, Takakura T, Kotsubo H, Tanaka T, Aikawa Y, Shiozawa S, Hirono S.
    • Journal Title

      J Med Chem 49

      Pages: 80-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Heat shock protein 90 is required for increased DNA binding activity of activator protein-1, a heterodimer of Fos/JunD, in rheumatoid synovial cells under inflammatory stimuli.2005

    • Author(s)
      Murata M, Miura Y, Hashiramoto A, Kitamura H, Kawasaki H, Shiozawa K, Yoshiya S, Baba H, Chihara K, Shiozawa S.
    • Journal Title

      Int J Mol Med 15

      Pages: 645-653

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Estrogen specifically stimulates expression and production of osteoprotegerin from rheumatoid synovial fibroblasts.2005

    • Author(s)
      Mitani M, Miura Y, Saura R, Kitagawa A, Fukuyama T, Hashiramoto A, Shiozawa S, Kurosaka M, Yoshiya S.
    • Journal Title

      Int J Mol Med 5

      Pages: 827-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Whole genome association study of rheumatoid arthritis using 27039 microsatellites.2005

    • Author(s)
      Tamiya G, Shinya M, Imanishi T, Ikuta T, Makino S, Okamoto K, Furugaki K, Matsumoto T, Mano S, Ando S, Nozaki Y, Yukawa W, Nakashige R, Yamaguchi D, Ishibashi H, Yonekura M, Yoshikawa Y, Fujimoto K, Oka A, Chiku S, Linsen SEV, Giphart MJ, Hoshina Y, Suzuki Y, Hotta T, Mochida J, Minezaki, Komai K, Shiozawa S, et al.
    • Journal Title

      Human Mol Genet 14

      Pages: 2305-2321

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Death receptor 3 (DR3)gene duplication in a chromosome region 1p36.3 : Gene duplication is more prevalent in rheumatoid arthritis patients.2004

    • Author(s)
      Osawa K, Takami N, Shiozawa K, Hashiramoto A, Shiozawa S.
    • Journal Title

      Gene Immunity 5

      Pages: 439-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Design, synthesis, and biological evaluation of new cyclic disulfide decapeptides that inhibit the binding of AP-1 to DNA.2004

    • Author(s)
      Tsuchida K, Chaki H, Takakura T, Yokotani J, Aikawa Y, Shiozawa S, Gouda H, Hirono S.
    • Journal Title

      J Med Chem 47

      Pages: 4239-4246

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Human wee 1 kinase is directly transactivated by and increased in association with c-Fos/AP-1 : Rheumatoid synovial cells overexpressing these genes go into aberrant mitosis.2003

    • Author(s)
      Kawasaki H, Komai K, Nakamura M, Yamamoto E, OuYang Z, Nakashima T, Hashiramoto A, Shiozawa K, Ishikawa H, Kurosaka M, Shiozawa S.
    • Journal Title

      Oncogene 22

      Pages: 6839-6844

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Generalized pustular psoriasis : strategy for identification of psoriasis susceptibility gene.2003

    • Author(s)
      Muto M, Ohmura A, Hamamoto Y, Konishi Y, Shiozawa S, Youn JI, Tanifuji J, Furuya K, Sasazuki T, Ogawa H.
    • Journal Title

      Arch Dermatol Res 295

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Characterization of novel alternative splicing variants of the mouse MCF-2 (DBL) proto-oncogene.2003

    • Author(s)
      Komai K, Mukae-Sakairi N, Kitagawa M, Shiozawa S.
    • Journal Title

      Biochem Biophys Res Commun 309

      Pages: 906-909

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Metabolism of 26, 26, 26, 27, 27, 27-F6-1a, 25-dihydroxyvitamin D3 by CYP24 : Species-based difference between humans and rats.2003

    • Author(s)
      Sakaki T, Sawada N, Abe D, Komai K, Shiozawa S, Nonaka Y, Nakagawa K, Okano T, Ohta M, Inouye K.
    • Journal Title

      Biochem Pharmacol 65

      Pages: 1957-1965

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] p21 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients.2003

    • Author(s)
      Hikasa M, Yamamoto E, Kawasaki H, Komai K, Shiozawa K, Hashiramoto A, Miura Y, Shiozawa S.
    • Journal Title

      Biochem Biophys Res Commun 304

      Pages: 143-147

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Alternative splicing variants of the human DBL (MCF-2) proto-oncogene.2002

    • Author(s)
      Komai K, Okayama R, Kitagawa M, Yagi H, Chihara K, Shiozawa S.
    • Journal Title

      Biochem Biophys Res Commun 299

      Pages: 455-458

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] c-Fos/ activator protein-1 transactivates wee 1 kinase at G1/S to inhibit premature mitosis in antigen-specific Th1 cell.2001

    • Author(s)
      Kawasaki H, Komai K, Ouyang Z, Murata M, Hikasa M, Ohgiri M, Shiozawa S.
    • Journal Title

      EMBO J 20(16)

      Pages: 4618-4627

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Alternatively-spliced EDA-containing fibronectin in synovial fluid as a predictor of rheumatoid joint destruction.2001

    • Author(s)
      Shiozawa K
    • Journal Title

      Rheumatology 40巻7号

      Pages: 739-742

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Alternatively-spliced EDA-containing fibronectin in synovial fluid as a predictor of rheumatoid joint destruction.2001

    • Author(s)
      Shiozawa K, Hino K, Shiozawa S.
    • Journal Title

      Rheumatology 40(7)

      Pages: 739-742

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Platelet-activating factor acetylhydrolase gene mutation in Japanese children with Escherichia coli O157-associated hemolytic uremic syndrome.2000

    • Author(s)
      Xu H, Iijima K, Shirakawa T, Shiozawa S, Miwa M, Yamaoka K, Kawamura N, Nakamura H, Yoshikawa N.
    • Journal Title

      Am J Kidney Dis 36

      Pages: 42-46

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Spontaneous, cytokine regulated c-fos gene expression in rheumatoid synovial cells resistance to cytokine Stimulation when the c-fos gene is overexpressed.2000

    • Author(s)
      Shimizu K, Kawasaki H, Morisawa T, Nakamura M, Yamamoto E, Yoshikawa N, Doita M, Shiozawa K, Yonehara S, Chihara K, Shiozawa S.
    • Journal Title

      Ann Rheum Dis 59(8)

      Pages: 636-640

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Dual metabolic pathway of 25-hydroxyvitamin D3 catalyzed by human CYP24.2000

    • Author(s)
      Sakai T, Sawada N, Komai K, Shiozawa S, Yamada S, Yamamoto K, Ohyama Y, Inouye K.
    • Journal Title

      Eur J Biochem 267(20)

      Pages: 6158-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] A Bayesian approach to identifying rheumatoid arthritis disease gene.2000

    • Author(s)
      Tsukamoto Y, Shiozawa S.
    • Journal Title

      Bull Health Sci Kobe 16

      Pages: 45-50

    • NAID

      110004599687

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Anchorage on fibronectin via VLA-5 (α5β1 integrin) protects rheumatoid synovial cells from Fas-induced apoptosis.

    • Author(s)
      Kitagawa A, Miura Y, Saura R, Mitani M, Ishikawa H, Hashiramoto A, Yoshiya S, Shiozawa S, Kurosaka M.
    • Journal Title

      Ann Rheum Dis (in press.)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] The promoter region of death receptor 3 (DR3) is specifically hypermethylated in rheumatoid synovial cells.

    • Author(s)
      Takami N, Osawa K, Miura Y, Komai K, Taniguchi M, Shiraishi M, Sato K, Iguchi T, Shiozawa K, Hashiramoto A, Shiozawa S.
    • Journal Title

      Arthritis Rheum (in press.)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204059
  • [Journal Article] Serum levels and pharmacodynamics of methotrexate and its metabolite 7-hydroxy methotrexate in Japanese patients with rheumatoid arthritis treated with 2mg capsule of methotrexate 3 times a week.

    • Author(s)
      Shiozawa K
    • Journal Title

      Mod Rheumatol (in press)

    • Data Source
      KAKENHI-PROJECT-17659301
  • [Presentation] Endosome-to-cytoplasm pathway via Sec61 and proteasomal degradation as an essential component of antigen cross-presentation and the lupus tissue injury in systemic lupus erythematosus (SLE): Extension of our self-organized criticality theory.2016

    • Author(s)
      Tsumiyama K, Shiozawa S
    • Organizer
      The American Association of Immunologist, 103rd annual meeting,
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2016-05-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] Increase of endosomal Sec61 enhances antigen cross-presentation and induces immune glomerular injury: a novel ‘self-organized criticality theory’ explaining the cause of systemic lupus erythematosus.2015

    • Author(s)
      Tsumiyama K, Shiozawa S.
    • Organizer
      The American Association of Immunologist, 102nd annual meeting,
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2015-05-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] Specifying the autoantibody-inducing CD4 T cell causing systemic lupus erythematosus out of PD-1+CD45RBlo122lo CD4 subpopulation using mass spectrometry.2015

    • Author(s)
      Shiozawa S, Miyazaki Y, Tsumiyama K.
    • Organizer
      The American Association of Immunologist, 102nd annual meeting,
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2015-05-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] Self-organized criticality theory in the pathogenesis of SLE.2014

    • Author(s)
      Shiozawa S
    • Organizer
      Symposium on Human Papilloma Vaccines.
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] The autoantibody-inducing CD4 T cell (aiCD4 T cell) causing systemic lupus erythematosus (SLE) belongs to PD-1+CD45RBlo122lo CD4 subpopulation.2014

    • Author(s)
      Miyazaki Y, Tsumiyama K, Shiozawa S.
    • Organizer
      The 101st Annual Meeting of American Association of Immunologists
    • Place of Presentation
      Pittsburgh, USA
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] Sec61 plays an essential role in facilitating antigen cross-presentation2014

    • Author(s)
      Tsumiyama K, Shiozawa S.
    • Organizer
      The 101st Annual Meeting of American Association of Immunologists
    • Place of Presentation
      Pittsburgh, USA
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] MMP3 as a predictor identifying a subgroup of rheumatoid patients who are successfully treated with methotrexate (MTX) alone but still subject to radiographic progression.2013

    • Author(s)
      Shiozawa S, Tanaka Y, Yoshihara R, Murata M, Yamane T, Tanaka C, Yo N, Shiozawa K.
    • Organizer
      ACR/ARHP Annual Meeting 13
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] PD-1+CD45RBlo 122lo autoantibody-inducing CD4 T cell (aiCD4 T cell) as a key in the pathogenesis of systemic lupus erythematosus.2013

    • Author(s)
      Miyazaki Y, Tsumiyama K, Shiozawa S.
    • Organizer
      ACR/ARHP Annual Meeting 13
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] Anti-carbamylated protein antibody in Japanese patients with rheumatoid arthritis.2013

    • Author(s)
      Shiozawa S, Trouw LA, Shiozawa K.
    • Organizer
      ACR/ARHP Annual Meeting 13
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] Specifying the autoantibody-inducing CD4 T cell (aiCD4 T cell) causing systemic lupus erythematosus (SLE) out of PD-1+CD45RBlo122lo CD4 subpopulation using mass spectrometry.

    • Author(s)
      Shiozawa S, Miyazaki Y, Tsumiyama K.
    • Organizer
      Immunology 2015 (102th Annual Meeting of AAIS)
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2015-05-08 – 2015-05-12
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] Sec 61 plays an essential role in facilitating antigen cross-presentation.

    • Author(s)
      Tsumiyama K, Shiozawa S.
    • Organizer
      Immunology 2014 (101th Annual Meeting of AAIS)
    • Place of Presentation
      Pittsburg, USA
    • Year and Date
      2014-05-02 – 2014-05-06
    • Data Source
      KAKENHI-PROJECT-25515003
  • [Presentation] The autoantibody-inducing CD4 T cell (aiCD4 T cell) causing SLE belongs to PD-1+CD45RBlo122lo CD4 subpopulation.

    • Author(s)
      Miyazaki Y, Tsumiyama K, Shiozawa S.
    • Organizer
      Immunology 2014 (101th Annual Meeting of AAIS)
    • Place of Presentation
      Pittsburgh, USA
    • Year and Date
      2014-05-02 – 2014-05-06
    • Data Source
      KAKENHI-PROJECT-25515003
  • 1.  TSUKAMOTO Yasuo (30031149)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  ISHIKAWA Hitoshi (30107958)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  KOMAI Koichiro (40304117)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 4.  OKADA Yasunori (00115221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SHIKATA Hideo (00170853)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OHNO Shinsuke (70019868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  GOKO Hideki (80170447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MIURA Yasushi (60346244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 9.  HASHIRAMOTO Akira (80346246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 10.  CHADA Kiran
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  田中 啓一
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  D'ARMIENTO J
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ARMIENTO Jeanine D
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  DARMIENTO Je
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  CHADA Kirari
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  EECKHOUT Yve
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  伊藤 光宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  辻 佐智代
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  宮澤 正顕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  外丸 詩野
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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