OTSUKI Takemi 大槻剛巳

… Alternative Names

大槻剛己オオツキタケミ

大槻剛巳オオツキタケミ

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Researcher Number	40160551
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2003 – 2022: KAWASAKI MEDICAL SCHOOL, PROFESSOR, 医学部, 教授 2014: 川崎医科大学, 衛生学, 教授 1997 – 2002: 川崎医科大学, 医学部, 助教授 1991: 川崎医科大学, 医学部, 講師 1989: 川崎医科大学, 内科学, 助手
Review Section/Research Field	Principal Investigator Hygiene / Hygiene / 内科学一般 Except Principal Investigator Hygiene and public health / Hygiene / Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / General surgery / Hematology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Radiation science / Applied molecular and cellular biology
Keywords	Principal Investigator IL-10 / T細胞 / 制御性T細胞 / アスベスト / 悪性中皮腫 / CXCR3 / T CELL / ASBESTOS / T細胞受容体 / アポトーシス … More / STATIN / ATRA / 遺伝子発現 / apoptosis / Fas ligand / Fas / 珪酸 / 腫瘍免疫 / 免疫 / 自己免疫疾患 / 細胞株 / 曝露 / 発癌 / シリカ / CANCER PREVENTION / MALIGNANT MESOTHELIOMA / REGULATORYT CELL / TGF-BETA / 石綿肺 / Bcl-2 / 発癌予防 / TGFβ / T CELL RECEPTOR / APOPTOSIS / CELLINE / REGULATORY T CELL / SILICA / MAPキナーゼ / ミトコンドリア経路 / 活性酸素種 / 培養株 / PROTEIN EXPRESSION / ANTI-HER2-ANTIBODY / MAP-KINASE / GENE EXPRESSION / CELL CULTURE / MYELOMA / ビスフォスフォート剤 / サリドマイド / 蛋白発現 / 抗HER2抗体 / MAP-kinaseシグナル伝達 / 細胞培養 / 骨髄腫 / alternative splicing / caspase / silicosis / silica compound / Fas ligahd / 選択的splicing / Caspase / 珪肺症 / 珪酸化合物 / T細胞機能 / NK活性 / 長期モニター / サイトカイン / 活性化 / NK細胞 / 室内気質 / マイナス荷電粒子 / 免疫担当細胞 / Fas分子 / 自己免疫異常 / アレルギー / 環境中物質 … More Except Principal Investigator 珪肺症 / 自己免疫疾患 / 免疫 / 悪性中皮腫 / アポトーシス / 石綿 / 自己免疫 / 産業衛生 / 珪酸 / 中皮腫 / アスベスト / 自己抗体 / バイオマーカー / 単球 / チタン / ナノ毒性 / 制御性T細胞 / FOXP3 / HER1 / Hypoxia / 低酸素環境 / ER / 乳癌 / preventive medicine / silicosis / autoimmune response / Work-related diseases / HLA型 / Fas / リンパ球 / HLA class II / T細胞 / 細胞骨格 / 赤血球膜 / トランスクリプトーム / 環境性粒子状物質 / 滑膜肉腫 / がん抗原SSX / クロマチン制御 / 肝細胞癌 / x染色体不活性化 / 融合遺伝子 / 分子標的薬 / X染色体転座 / 悪性軟部肉腫 / BET抑制剤 / オートファジー / Ca2+ / カルシウムイオン / リソソーム / 免疫毒性 / 珪酸曝露 / 免疫応答 / perforin / granzyme B / IL-15 / CTL / 予防 / 空砲 / ヒト / エンドソーム / 空胞 / DNA損傷 / ミトコンドリア / DNAメチル化 / FoxP3 / 腫瘍免疫 / suppressive effect / CD4+CD25-T cell / CD4+CD25+ regulatory T cell / autoimmune disease / autoantibody / immunological disorder / 末梢血単核細胞 / 細胞増殖抑制能 / CD4^+CD25^-T細胞 / CD4^+CD25^+制御性T細胞 / 自己反応性T細胞 / 抗核抗体 / 免疫異常 / Antiestrogen / Hypoxic cytotoxin / Signal transduction inhibitor / Estrogen receptor / Endocrine resistance / Berast cancer / HER1 シグナル伝達阻害剤 / Bcl-2 / p21 / 抗エストロゲン剤 / 低酸素選択的細胞毒 / HER1シグナル伝達阻害剤 / ホルモン療法抵抗性 / RAD 51 family / homologous recombinational repair / cell cycle / tyrosinase related protein-2 / melanogenesis / Elkind recovery / radiation resistance / malignant melanoma / RAD51 family / 相同組換え修復 / 細胞周期 / TRP-2 / メラニン合成能 / エルカインド回復 / 放射線抵抗性 / 悪性黒色腫 / Cell Line / Progesterone Recepter / Vascular Endothelial Growth Factor / Hypoxia-inducible Factor-Iα / Estrogen Receptor / Hormone Resistance / Breast Cancer / VEGF / 細胞株 / PgR / VEGE / HIF-1α / 低酸素 / ホルモン療法耐性 / HLA typing / silicate / silicossis / 有害物質感受性 / 予防医学 / 珪酸塩化合物 / 作業関連疾患 / HLA-typing / silica silicate / 珪酸症 / Fas ligand / Apoptosis / T lymphocytes / Sillicate / Silica / Autoimmunity / 珪酸化合物 / 作業関連物質 / 免疫動態 / 粉塵曝露 / 衛生 / 動物実験 / 代替法 / アレルギー / アレルギー・ぜんそく / 癌疾患 / 免疫機能 / 遊離ケイ酸 / 強皮症 / 珪肺 / NK細胞 / 全身性強皮症 / シリカ / ヒト樹状細胞 / γ-ポリグルタミン酸 / 親水性クロマト / 植物抗原性 / Th2応答 / 淡水性植物 / サイトカイン / γポリグルタミン酸 / Asn-糖鎖 / Cry j1 / 樹状細胞 / 糖鎖ポリマー / ルイスa抗原 / 多量精製 / Th2免疫応答抑制 / スギ花粉アレルゲン / 植物抗原性糖鎖 / N-グリカン / 血液幹細胞 / 分化誘導 / iPS細胞 / ES細胞 / 免疫制御性T細胞 / センダイ・ウイルス / iPS化 / MAIT細胞 / プロテインチップ / 膜輸送能 / 膜蛋白分画4、2 / 溶血性貧血 / 膜成分の発現 / 血液型 Less

Development of irregular X-chromosome inactivation-specific targeted therapy
- Principal Investigator
  
  Ito Tatsuo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kawasaki Medical School
環境物質誘発性自己免疫疾患発症のトリガーイベントの探索
- Principal Investigator
  
  李順姫
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kawasaki Medical School
Exploration of immunological biomarker for diagnosis of malignant mesothelioma on the basis of transcriptome analysis
- Principal Investigator
  
  Nishimura Yasumitsu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kawasaki Medical School
Exploratory research for toxic machinery of titanate nanosheet leading to immunological influences
- Principal Investigator
  
  Nishimura Yasumitsu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kawasaki Medical School
Immune cell polarization in autoimmune diseases caused by environmental particles
- Principal Investigator
  
  Lee Suni
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kawasaki Medical School
Comprehensive immunological-analyses for patients with malignant mesothelioma and diffuse pleural thickening
- Principal Investigator
  
  NISHIMURA YASUMITSU
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kawasaki Medical School
Analysis for mechanism involved in the suppressed immune response of CTL under exposure to asbestos
- Principal Investigator
  
  TAKEI NAOKO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kawasaki Medical School
Effect of short-term and long-term exposure of asbestos on regulatory T cells
- Principal Investigator
  
  Matsuzaki Hidenori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Prefectural University of Hiroshima
  Kawasaki Medical School
Immunotoxicity of titanate nanosheets
- Principal Investigator
  
  Nishimura Yasumitsu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  Kawasaki Medical School
Classification and alternative methods for sensitizers
- Principal Investigator
  
  Sato Kazuhiro
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  University of Fukui
Analysis for the effect of silica particle exposure on immune system
- Principal Investigator
  
  Lee Suni
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kawasaki Medical School
Analysis of suppression of Th2-type immune responses through innate immunity by glyco-polymer bearing plant antigenic N-glycans
- Principal Investigator
  
  MAEDA Megumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Okayama University
Comprehensive analysis for immunological characteristics of tumor and autoimmune diseases related with mineral particles and fibers
- Principal Investigator
  
  NISHIMURA Yasumitsu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
Protection against Asbestosis.
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
Construction of the experimental system about the immunity influence of an indoor dispositionPrincipal Investigator
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
Anaylisis of immunological alterations affecting asbestos-induced carcinogenesisPrincipal Investigator
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
環境中物質の免疫影響スクリーニングシステム構築Principal Investigator
- Principal Investigator
  
  大槻剛巳
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
ANALYSIS OF IMMUNOLOGICAL TARGET MOLECULES FOR MOLECULAR PREVENTION OF ASBESTOS-RELATED TUMOR FORMATIONIN CASES WHO EXPOSED ASBESTOSPrincipal Investigator
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
FALURE OF SELF TOLERANCE INDUCED BY ENVIRONMELAL SUBSTANCES : AUTOIMMUNE DYSREGULATION FOUND IN SILICOSIS PATIENIS AS A MODELPrincipal Investigator
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Phenotypic and functional alteration of regulatory T cells in the peripheral blood of patients with silicosis
- Principal Investigator
  
  HYODOH Fuminori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
EXTRACTION OF FACTORS RELATED TO THE ONCOGENESIS, PROGRESSION AND SENSITIVITY TO THE THERAPEUTIC AGENTS IN HUMAN MYELOMA CELLS AS IN VITRO MODELPrincipal Investigator
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  KAWASAKI MEDICAL SCHOOL
The elucidation of the radiation resistance in melanoma : the relationship between melanogenesis and Elkind recovery
- Principal Investigator
  
  HIRATSUKA Junichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kawasaki Medical School
EXPERIMENTAL STUDY ON ACTION MECHANISMS OF RESISTANCE TO HORMONAL THERAPY AND OVERCOMING THIS RESISTANCE IN BREAST CANCER
- Principal Investigator
  
  KUREBAYASHI Junichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  KAWASAKI MEDICAL SCHOOL
プロテインチップを用いた珪肺症患者における免疫学的病態の解析
- Principal Investigator
  
  UEKI Ayako
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
Risk factors analysis using HLA typing for preventive medicine of worker's immunological sensitivities against silica dust.
- Principal Investigator
  
  UEKI Ayako
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Experimental Study on Overcoming Resistance to Hormonal Therapy in Breast Cancer
- Principal Investigator
  
  KUREBAYASHI Jyunichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Analysis of HLA disease association among the patients patients with silicosis-To make a check list to prevent work-related diseases.
- Principal Investigator
  
  UEKI Ayako
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
Occupational exposure of toxic materials and development of autoimmune diseases
- Principal Investigator
  
  UEKI Ayako
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Research for immunodysregulation and acquisition of autoimmunity induced by silica compoundsPrincipal Investigator
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  KAWASAKI MEDICAL SCHOOL
わが国に特有な赤血球膜異常症,特に膜蛋白分画4,2の病態に関する遺伝生化学的研究
- Principal Investigator
  
  八幡義人
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki Medical School
二相液体培養法による遺伝性赤血球膜疾患赤芽球細胞膜の発生分化に関する生化学的研究
- Principal Investigator
  
  八幡義人
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki Medical School

[Book] "Asbestos fiber and immunological effects: Do immunological effects play any role in asbestos-related diseases?" in Malignant Pleural Mesothelioma; Advances in Pathogenesis, Diagnosis, and Treatments2021
- Author(s)
  Yasumitsu Nishimura, Naoko Kumagai-Takei, Suni Lee, Kei Yoshitome, Tatsuo Ito, Takemi Otsuki
- Total Pages
  352
- Publisher
  Springer
- ISBN
  9789811591587
- Data Source
  KAKENHI-PROJECT-19H03892
[Book] Reduction of anti-tumor immunity caused by asbestos exposure. In: Allergy and Immunotoxicology in Occupational Health - The Next Step2020
- Author(s)
  Kumagai-Takei N, Lee S, Matsuzaki H, Maeda M, Sada N,Yu M, Yoshitome K, Nishimura Y, Otsuki T.
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-16K09114
[Book] Allergy and Immunotoxicology in Occupational Health - The Next Step2020
- Author(s)
  Lee S, Yamamoto S, Hayashi H, Matsuzaki H, Kumagai-Takei N, Hatayama T, Yu M, Ysoshitome K, Kusaka M, Nishimura Y, Otsuki T.
- Total Pages
  17
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-20K10437
[Book] "Suppressed immune system caused by exposure to asbestos and malignant mesothelioma" in Asbestos-related Diseases2020
- Author(s)
  Yasumitsu Nishimura, Naoko Kumagai-Takei, Suni Lee, Kei Yoshitome and Takemi Otsuki
- Total Pages
  14
- Publisher
  IntechOpen
- ISBN
  9781838808334
- Data Source
  KAKENHI-PROJECT-19H03892
[Book] Current Topics in Environmental Health and Preventive Medicine2020
- Author(s)
  Lee S, Yamamoto S, Hayashi H, Matsuzaki H, Kumagai-Takei N, Hatayama T, Yu M, Ysoshitome K, Kusaka M, Nishimura Y, Otsuki T
- Publisher
  Springer Japan
- ISBN
- Data Source
  KAKENHI-PROJECT-17K09171
[Book] "Reduction of anti-tumor immunity caused by asbestos exposure" in Allergy and Immunotoxicology in Occupational Health - The Next Step2020
- Author(s)
  Kumagai-Takei Naoko, Lee Suni, Matsuzaki Hidenori, Maeda Megumi, Sada Nagisa, Yu Min, Yoshitome Kei, Nishimura Yasumitsu, Otsuki Takemi
- Total Pages
  13
- Publisher
  Springer Singapore
- ISBN
  9789811547355
- Data Source
  KAKENHI-PROJECT-19H03892
[Book] "Immune Alteration Caused by Fibrous and Particulate Environmental Substances." In Environmental Factors Affecting Human Health2019
- Author(s)
  Kumagai-Takei, N, Lee, S, Yoshitome, K, Sada, N, Nishimura, Y and Otsuki, T
- Total Pages
  17
- Publisher
  IntechOpen
- ISBN
  9781789855289
- Data Source
  KAKENHI-PROJECT-19H03892
[Book] Environmental Factors affecting Human Health2019
- Author(s)
  Kumagai-Takei N, Lee S, Yoshitome K, Sada N, Nishimura Y, Otsuki T
- Publisher
  IntechOpen
- ISBN
  9781789855289
- Data Source
  KAKENHI-PROJECT-16H05264
[Book] Immune alteration caused by fibrous and particulate environmental substances. In: Environmental Factors affecting Human Health.2019
- Author(s)
  Kumagai-Takei N, Lee S, Yoshitome K, Sada N, Nishimura Y, Otsuki T.
- Total Pages
  17
- Publisher
  IntechOpen Limited
- Data Source
  KAKENHI-PROJECT-16K09114
[Book] Cytotoxicity2018
- Author(s)
  Yasumitsu Nishimura, Daisuke Yoshioka, Naoko Kumagai-Takei, Suni Lee, Hidenori Matsuzaki, Kei Yoshitome, Takemi Otsuki
- Publisher
  IntechOpen
- ISBN
  9781789234312
- Data Source
  KAKENHI-PROJECT-18K19714
[Book] Lymphocyte2018
- Author(s)
  Kumagai-Takei N, Lee S, Matsuzaki H, Sada N, Yoshitome K, Nishimura Y, Otsuki T
- Publisher
  IntechOpen
- ISBN
  9789535164456
- Data Source
  KAKENHI-PROJECT-16H05264
[Book] Cytotoxicity2018
- Author(s)
  Yasumitsu Nishimura, Daisuke Yoshioka, Naoko Kumagai-Takei, Suni Lee, Hidenori Matsuzaki, Kei Yoshitome, Takemi Otsuki
- Publisher
  IntechOpen
- ISBN
  9789535158691
- Data Source
  KAKENHI-PROJECT-15K15245
[Book] Alteration of perforin status caused by asbestos exposure in CTL and NK cellss. In. "Advances in Medicine and Biology.2017
- Author(s)
  Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Yamamoto S, Ikeda M, Hatayama T, Maeda M, Otsuki T.
- Publisher
  NOVA Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-16K09114
[Book] Natural Killer Cells2017
- Author(s)
  Yasumitsu Nishimura, Naoko Kumagai-Takei, Suni Lee, Hidenori Matsuzaki, Kei Yoshiotme and Takemi Otsuki
- Total Pages
  177
- Publisher
  IntechOpen
- ISBN
  9789535136729
- Data Source
  KAKENHI-PROJECT-16H05264
[Book] Advances in Medicine and Biology. Volume 1232017
- Author(s)
  Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Yamamoto S, Ikeda M, Hatayama T, Maeda M, Otsuki T
- Total Pages
  257
- Publisher
  NOVA publisher,
- ISBN
  9781536121780
- Data Source
  KAKENHI-PROJECT-16H05264
[Book] Reduction of anti-tumor immunity caused by asbestos exposure.In. Asbestos: Risk Assessment, Health Implications and Impacts on the Environment.2016
- Author(s)
  Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Yamamoto S, Hatayama T, Maeda M, Otsuki T.
- Publisher
  NOVA Scientific Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-16K09114
[Book] Allergy and Immunotoxicology in Occupational Health2016
- Author(s)
  Otsuki T, Di Gioacchino M, Petrarca C
- Total Pages
  152
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-16H05264
[Book] Allergy and immunotoxicology in occupational health2016
- Author(s)
  Otsuki T, Petrarca C, Gioacchino MD
- Total Pages
  152
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25293148
[Book] Chapter９ Immunostimulation by silica particles and the development of autoimmune dysregulation in "Immune Response Activation"2014
- Author(s)
  Lee S, Maeda M, Hayashi H, Matsuzaki H, Kumagai-Takei N, Nishimura Y, Otsuki T
- Total Pages
  274
- Publisher
  InTech publisher
- Data Source
  KAKENHI-PROJECT-24590770
[Book] Immunostimulation2014
- Author(s)
  Lee S, Maeda M, Hayashi H, Matsuzaki H, Kumagai-Takei N, Nishimura Y, Otsuki T.
- Total Pages
  18
- Publisher
  InTech publisher
- Data Source
  KAKENHI-PROJECT-25460825
[Book] Encyclopedia of Metalloproteins2013
- Author(s)
  Takei-Kumagai N, Lee S, Matsuzaki H, Hayashi H, Maeda M, Nishimura Y, Otsuki T
- Publisher
  Springer Science+Business Media
- Data Source
  KAKENHI-PROJECT-24590770
[Book] Malignant Mesothelioma2012
- Author(s)
  Nishimura Y, Maeda M, Kumagai-Takei N, Matsuzaki H, Lee S, Fukuoka K, Nakano T, Kishimoto T, Otsuki T
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-24590770
[Book] 住居医学(IV)(筏義人,吉田修(編著))(アスベストの免疫影響)2010
- Author(s)
  大槻剛巳,西村泰光,前田恵,三浦由恵,熊谷直子,林宏明
- Publisher
  米田出版千葉県市川市
- Data Source
  KAKENHI-PROJECT-20390178
[Book] アスベストの免疫影響.In住居医学(IV).筏義人,吉田修(編著)2010
- Author(s)
  大槻剛巳, 他
- Publisher
  米田出版千葉県市川市
- Data Source
  KAKENHI-PROJECT-20390178
[Book] 炎症・再生医学事典(編:松島綱治,西脇徹)(アスベストーシス ISBN978-4-254-30099-4C3547)2009
- Author(s)
  林宏明,西村泰光,前田恵,大槻剛巳
- Publisher
  朝倉書店,東京
- Data Source
  KAKENHI-PROJECT-20390178
[Book] Asbestos : Risks, Environment and Impact.(Eds : Antonio Soto, Gael Salazar)(Immunological effects of Asbestos. ISBN978-1-60692-053-4)2009
- Author(s)
  Otsuki T, Maeda M, Miura Y, Hayashi H, Murakami S, Kumagai N, Nishimura Y
- Publisher
  [○!C]2009 Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-20390178
[Book] Establishment of Negatively-charged Indoor Air Conditions and their Biological Effects. In Buildings and the Environment. Authors/Editors : Jonas Nemecek and Patrik Schulz2009
- Author(s)
  Otsuki T, Takahashi K, Mase A, Kawado T, Kotani M, Nishimura Y, Maeda M, Murakami S, Kumagai N, Hayashi H, Chen Y, Miura Y, Shirahama T, Yoshimatsu M, Morimoto K.
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-21659161
[Book] 分子予防環境医(アスベストーシス,シリコーシス松島綱治)
- Author(s)
  西村泰光,大槻剛巳,前田恵,熊谷直子
- Publisher
  本の泉社東京
- Data Source
  KAKENHI-PROJECT-20390178
[Book] Autoimmune Disorder/Book 1(Inech Open Access Publisher Immunological effects of silica and related dysregulation of autoimmunity. ISBN:978-953-308-70-9)
- Author(s)
  Kumagai N, Hayashi H, Maeda M, Miura Y, Nishimura Y, Fujimoto W, Otsuki T.
- Publisher
  (in press)
- Data Source
  KAKENHI-PROJECT-20390178
[Book] Autoimmune Disorders : Symptoms, Diagnosis and Treatment.(Editors : Maria E. Petro)(Dysregulation of Autoimmunity Caused by Silica Exposure : Fas-Mediated Apoptosis in T Lymphocytes Derived from Silicosis Patients. ISBN:978-1-61761-698-3)
- Author(s)
  Hayashi H, Nishimura Y, Hyodo F, Maeda M, Kumagai N, Miura Y, Kusaka M, Uragami K, Otsuki T.
- Publisher
  Nova Science Publishers, Inc.. Hauppauge, NY
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Increased production of matrix metalloproteinase-7 (MMP-7) by asbestos exposure enhances tissue migration of human regulatory T-like cells2021
- Author(s)
  Lee Suni、Yamamoto Shoko、Srinivas Bandaru、Shimizu Yurika、Sada Nagisa、Yoshitome Kei、Ito Tatsuo、Kumagai-Takei Naoko、Nishimura Yasumitsu、Otsuki Takemi
- Journal Title
  
  Toxicology
  
  Volume: 452 Pages: 152717-152717
- DOI
  10.1016/j.tox.2021.152717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03892
[Journal Article] Effect of IL-15 addition on asbestos-induced suppression of human cytotoxic T lymphocyte induction2021
- Author(s)
  Kumagai-Takei Naoko、Nishimura Yasumitsu、Matsuzaki Hidenori、Lee Suni、Yoshitome Kei、Ito Tatsuo、Otsuki Takemi
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: 26 Issue: 1 Pages: 1-11
- DOI
  10.1186/s12199-021-00967-9
- NAID
  210000158993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03892
[Journal Article] Ingredients such as trehalose and hesperidin taken as supplements or foods reverse alterations in human T?cells, reducing asbestos exposure-induced antitumor immunity2021
- Author(s)
  Yamamoto Shoko、Lee Suni、Ariyasu Toshio、Endo Shin、Miyata Satomi、Yasuda Akiko、Harashima Akira、Ohta Tsunetaka、Kumagai-Τakei Naoko、Ito Tatsuo、Shimizu Yurika、Srinivas Bandaru、Sada Nagisa、Nishimura Yasumitsu、Otsuki Takemi
- Journal Title
  
  International Journal of Oncology
  
  Volume: 58 Issue: 4 Pages: 1-9
- DOI
  10.3892/ijo.2021.5182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03892
[Journal Article] The Effects of Asbestos Fibers on Human T Cells2020
- Author(s)
  Kumagai-Takei Naoko、Lee Suni、Srinivas Bandaru、Shimizu Yurika、Sada Nagisa、Yoshitome Kei、Ito Tatsuo、Nishimura Yasumitsu、Otsuki Takemi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 19 Pages: 6987-6987
- DOI
  10.3390/ijms21196987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03892
[Journal Article] Effect of asbestos exposure on differentiation and function of cytotoxic T lymphocytes2020
- Author(s)
  Kumagai-Takei Naoko、Nishimura Yasumitsu、Maeda Megumi、Hayashi Hiroaki、Matsuzaki Hidenori、Lee Suni、Yoshitome Kei、Ito Tatsuo、Otsuki Takemi
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: 25 Issue: 1 Pages: 1-6
- DOI
  10.1186/s12199-020-00900-6
- NAID
  210000158552
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03892
[Journal Article] Enhanced expression of nicotinamide nucleotide transhydrogenase (NNT) and its role in a human T cell line continuously exposed to asbestos2020
- Author(s)
  Yamamoto Shoko、Lee Suni、Matsuzaki Hidenori、Kumagai-Takei Naoko、Yoshitome Kei、Sada Nagisa、Shimizu Yurika、Ito Tastsuo、Nishimura Yasumitsu、Otsuki Takemi
- Journal Title
  
  Environment International
  
  Volume: 138 Pages: 105654-105654
- DOI
  10.1016/j.envint.2020.105654
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09157, KAKENHI-PROJECT-19H03892
[Journal Article] 結晶質シリカの生体影響について―自己寛容の破綻を中心に2019
- Author(s)
  李順姫、武井直子、西村泰光、吉留敬、大槻剛巳
- Journal Title
  
  労働衛生工学
  
  Volume: 58 Pages: 39-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09171
[Journal Article] Role of Nephronectin in Pathophysiology of Silicosis2019
- Author(s)
  Lee S, Honda M, Yamamoto S, Kumagai-Takei N, Yoshitome K, Nishimura Y, Sada N, Kon S, Otsuki T.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 10 Pages: 2581-2581
- DOI
  10.3390/ijms20102581
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07492, KAKENHI-PROJECT-17K09171
[Journal Article] アスベスト曝露と中皮腫発症の免疫学的スクリーニングマーカーの探索2018
- Author(s)
  西村泰光、武井直子、吉留敬、松﨑秀紀、李順姫、大槻剛巳
- Journal Title
  
  繊維状物質研究
  
  Volume: 5 Pages: 102-106
- NAID
  40021640185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05264
[Journal Article] Decrease in Intracellular Perforin Levels and IFN-γ Production in Human CD8+ T Cell Line following Long-Term Exposure to Asbestos Fibers2018
- Author(s)
  Kumagai-Takei Naoko、Nishimura Yasumitsu、Matsuzaki Hidenori、Lee Suni、Yoshitome Kei、Otsuki Takemi
- Journal Title
  
  Journal of Immunology Research
  
  Volume: 2018 Pages: 1-10
- DOI
  10.1155/2018/4391731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09114, KAKENHI-PROJECT-16H05264
[Journal Article] Skewing T helper cells exposed to asbestos fibers toward reduction of tumor immunity or activation of autoimmunity2018
- Author(s)
  Kumagai-Takei N, Lee S, Matsuzaki H, Maeda M, Yu M, Sada N, Yoshitome K, Nishimura Y, Otsuki T
- Journal Title
  
  Kawasaki Medical Journal
  
  Volume: 44 Pages: 33-40
- DOI
  10.11482/KMJ-E44(1)33
- NAID
  120006527968
- ISSN
  0385-0234, 2434-3404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05264
[Journal Article] 制御性T細胞の機能および細胞周期へのアスベスト曝露の影響2018
- Author(s)
  李順姫、松﨑秀紀、武井直子、吉留敬、西村泰光、大槻剛巳
- Journal Title
  
  繊維状物質研究
  
  Volume: 5 Pages: 130-135
- NAID
  40021640201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05264
[Journal Article] Inflammatory alteration of human T cells exposed continuously to asbestos.2018
- Author(s)
  Kumagai-Takei N, Yamamoto S, Lee S, Maeda M, Matsuzaki H, Sada N, Yu M, Yoshitome K, Nishimura Y, Otsuki T.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 2 Pages: 504-504
- DOI
  10.3390/ijms19020504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09114, KAKENHI-PROJECT-16H05264
[Journal Article] Aberrant expression of FoxP3 in a human T?cell line possessing regulatory T cell?like function and exposed continuously to asbestos fibers2018
- Author(s)
  Maeda Megumi、Matsuzaki Hidenori、Yamamoto Shoko、Lee Suni、Kumagai-Takei Naoko、Yoshitome Kei、Min Yu、Sada Nagisa、Nishimura Yasumitsu、Otsuki Takemi
- Journal Title
  
  Oncology Reports
  
  Volume: 40 Pages: 748-58
- DOI
  10.3892/or.2018.6481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05264
[Journal Article] Search for biomarkers of asbestos exposure and asbestos-induced cancers in investigations of the immunological effects of asbestos2017
- Author(s)
  Matsuzaki Hidenori、Kumagai-Takei Naoko、Lee Suni、Maeda Megumi、Sada Nagisa、Hatayama Tamayo、Yamamoto Shoko、Ikeda Miho、Yoshitome Kei、Min Yu、Nishimura Yasumitsu、Otsuki Takemi
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: 22 Issue: 1
- DOI
  10.1186/s12199-017-0661-4
- NAID
  210000130229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788
[Journal Article] Clinical evaluation of CENP-B and Scl-70 autoantibodies in silicosis patients.2017
- Author(s)
  Lee, S., Hayashi, H., Kumagai-Takei, N., Matsuzaki, H., Yoshitome, K., Nishimura, Y., Uragami, K., Kusaka, M., Yamamoto, S., Ikeda, M., Hatayama, T., Fujimoto, W., Otsuki, T.
- Journal Title
  
  Exp. Ther. Med.
  
  Volume: 13 Issue: 6 Pages: 2616-2622
- DOI
  10.3892/etm.2017.4331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08788
[Journal Article] Induction of IL-17 production from human peripheral blood CD4+ cells by asbestos exposure2017
- Author(s)
  Maeda Megumi、Chen Ying、Lee Suni、Kumagai-Takei Naoko、Yoshitome Kei、Matsuzaki Hidenori、Yamamoto Shoko、Hatayama Tamayo、Ikeda Miho、Nishimura Yasumitsu、Otsuki Takemi
- Journal Title
  
  International Journal of Oncology
  
  Volume: 50 Issue: 6 Pages: 2024-2032
- DOI
  10.3892/ijo.2017.3991
- NAID
  120006363419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788
[Journal Article] Titanate nanosheets cause caspase-dependent apoptosis of human immune cells with giant vacuole formation through endosomal defect in monocytes2017
- Author(s)
  Nishimura Yasumitsu、Yoshioka Daisuke、Kumagai-Takei Naoko、Lee Suni、Matsuzaki Hidenori、Yoshitome Kei、Otsuki Takemi
- Journal Title
  
  Toxicology Letters
  
  Volume: 280 Pages: S182-S183
- DOI
  10.1016/j.toxlet.2017.07.512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15245
[Journal Article] アスベト曝露と細胞傷害性顆粒．2017
- Author(s)
  武井直子，西村泰光，松﨑秀紀，李順姫，吉留敬，幡山圭代，山本祥子，池田美穂，大槻剛巳.
- Journal Title
  
  臨床環境医学 26(1): 31-37, 2017
  
  Volume: 26 Pages: 31-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09114
[Journal Article] Accelerated cell cycle progression of human regulatory T cell-like cell line caused by continuous exposure to asbestos fibers2017
- Author(s)
  Lee Suni、Matsuzaki Hidenori、Maeda Megumi、Yamamoto Shoko、Kumagai-Takei Naoko、Hatayama Tamayo、Ikeda Miho、Yoshitome Kei、Nishimura Yasumitsu、Otsuki Takemi
- Journal Title
  
  International Journal of Oncology
  
  Volume: 50 Issue: 1 Pages: 66-74
- DOI
  10.3892/ijo.2016.3776
- NAID
  120006349212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05264
[Journal Article] FoxO1 regulates apoptosis induced by asbestos in the MT-2 human T-cell line2016
- Author(s)
  Matsuzaki, H. Lee, S. Maeda, M. Kumagai-Takei, N. Nishimura, Y. Otsuki, T.
- Journal Title
  
  J Immunotoxicol
  
  Volume: 13 Issue: 5 Pages: 620-627
- DOI
  10.3109/1547691x.2016.1143539
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05264
[Journal Article] The proliferative effects of asbestos-exposed peripheral blood mononuclear cells on mesothelial cells2016
- Author(s)
  Maki Y, Nishimura Y, Toyooka S, Soh J, Tsukuda K, Shien K, Furukawa M, Muraoka T, Ueno T, Tanaka N, Yamamoto H, Asano H, Maeda M, Kumagai-Takei N, Lee S, Matsuzaki H, Otsuki T, Miyoshi S
- Journal Title
  
  Oncology Letters
  
  Volume: 11 Issue: 5 Pages: 3308-3316
- DOI
  10.3892/ol.2016.4412
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788
[Journal Article] ヒトT細胞株への白石綿・青石綿継続曝露に伴う細胞特性の変化．2016
- Author(s)
  李順姫，前田恵，松﨑秀紀，武井直子，山本祥子，幡山圭代，吉留敬，西村泰光，大槻剛巳．
- Journal Title
  
  日本予防医学雑誌
  
  Volume: 10 Pages: 119-125
- NAID
  40020930413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460825
[Journal Article] Environmental factors and human health: fibrous and particulate substance-induced immunological disorders and construction of a health-promoting living environment2016
- Author(s)
  Otsuki, T. Matsuzaki, H. Lee, S. Kumagai-Takei, N. Yamamoto, S. Hatayama, T. Yoshitome, K. Nishimura, Y.
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 21 Issue: 2 Pages: 71-81
- DOI
  10.1007/s12199-015-0499-6
- NAID
  210000000423
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788, KAKENHI-PROJECT-15K15245
[Journal Article] The Suppressed Induction of Human Mature Cytotoxic T Lymphocytes Caused by Asbestos Is Not due to Interleukin-2 Insufficiency2016
- Author(s)
  Kumagai-Takei, N. Nishimura, Y. Matsuzaki, H. Lee, S. Yoshitome, K. Hayashi, H. Otsuki, T.
- Journal Title
  
  J Immunol Res
  
  Volume: 2016 Pages: 1-10
- DOI
  10.1155/2016/7484872
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788, KAKENHI-PROJECT-16K09114
[Journal Article] Biological effects of Cloth containing specific ore powder in patients with pollen allergy.2016
- Author(s)
  Lee, S., Okamoto, H., Yamamoto, S., Hatayama, T., Matsuzaki, H., Kumagai-Takei, N., Yoshitome, K., Nishimura, Y., Sato, T., Kirita, Y., Fujii, Y., Otsuki, T.
- Journal Title
  
  Biomed. Environmental Sci.
  
  Volume: 29 Pages: 77-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08788
[Journal Article] Silica and mineral silicates causing autoimmune diseases.2016
- Author(s)
  Lee, S., Matsuzaki, H., Kumagai-Takei, N., Yamamoto, S., Hatayama, T., Yoshitome, K., Nishimura, Y., Otsuki, T.
- Journal Title
  
  Kawasaki Med. J.
  
  Volume: 42 Pages: 15-24
- NAID
  110010041934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08788
[Journal Article] FoxO1 Regulates Apoptosis Induced by Asbestos in the MT-2 Human T-Cell Line.2016
- Author(s)
  Matsuzaki, H., Lee, S., Maeda, M., Kumagai-Takei, N., Nishimura, Y., Otsuki, T.
- Journal Title
  
  Immunotoxicol.
  
  Volume: 13 Pages: 1-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08788
[Journal Article] Functional alteration of natural killer cells and cytotoxic T lymphocytes upon asbestos exposure and in malignant mesothelioma patients2015
- Author(s)
  Nishimura Y, Kumagai-Takei N, Matsuzaki H, Lee S, Maeda M, Kishimoto T, Fukuoka K, Nakano T, and Otsuki T
- Journal Title
  
  BioMed Res Int
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590770
[Journal Article] Enhancement of regulatory T cell-like suppressive function in MT-2 by long-term and low-dose exposure to asbestos.2015
- Author(s)
  Ying, C., Maeda, M., Nishimura, Y., Kumagai-Takei, N., Hayashi, H., Matsuzaki, H., Lee, S., Yoshitome, K., Yamamoto, S., Hatayama, T., Otsuki, T.
- Journal Title
  
  Toxicology
  
  Volume: 338 Pages: 86-94
- DOI
  10.1016/j.tox.2015.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08788
[Journal Article] Targeting LDH enzymes with a stiripentol analog to treat epilepsy.2015
- Author(s)
  Sada N, Lee S, Katsu T, Otsuki T, Inoue T
- Journal Title
  
  Science
  
  Volume: 347 Issue: 6228 Pages: 1362-1367
- DOI
  10.1126/science.aaa1299
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590114, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25253008
[Journal Article] Exposure to negaively-charged particle domitant air-conditions on human lymphocytes in vitro activates immunological responses.2015
- Author(s)
  Nishimura, Y., Takahashi, K., Masae, A., Kotani, M., Ami, K., Maeda, M., Shirahama, T., Lee, S., Matsuzaki, H., Kumagai-Takei, N., Yoshitome, K., Otsuki, T.
- Journal Title
  
  Immunobiology
  
  Volume: 220 Issue: 12 Pages: 1359-1368
- DOI
  10.1016/j.imbio.2015.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08788
[Journal Article] Enhancement of NK Cell Cytotoxicity Induced by Long-Term Living in Negatively Charged-Particle Dominant Indoor Air-Conditions.2015
- Author(s)
  Nishimura, Y., Takahashi, K., Mase, A., Kotani, M., Ami, K., Maeda, M., Shirahama, T., Lee, S., Matsuzaki, H., Kumagai-Takei, N., Yoshitome, K., Otsuki, T.
- Journal Title
  
  PlosOne
  
  Volume: 10 Issue: 7 Pages: e0132373-e0132373
- DOI
  10.1371/journal.pone.0132373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08788
[Journal Article] Investigating methods regarding diagnostic and prognostic biomarkers for malignant mesothelioma.2015
- Author(s)
  Matsuzaki, H., Lee, S., Kumagai-Takei, N., Yoshitome, K., Yamamoto S, Hatayama T, Nishimura, Y., Otsuki, T.
- Journal Title
  
  Kawasaki Med. J.
  
  Volume: 41 Pages: 13-22
- NAID
  110009926233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08788
[Journal Article] Functional alteration of natural killer cells and cytotoxic T lymphocytes upon asbestos exposure and in malignant mesothelioma patients.2015
- Author(s)
  Nishimura, Y., Kumagai-Takei, N., Matsuzaki, H., Lee, S., Maeda, M., Kishimoto, T., Fukuoka, K., Nakano, T., Otsuki, T.
- Journal Title
  
  Biomed. Res. Int.
  
  Volume: 2015 Pages: 1-9
- DOI
  10.1155/2015/238431
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08788, KAKENHI-PROJECT-25860470
[Journal Article] Functional properties of CD8+ lymphocytes in patients with pleural plaque and malignant mesothelioma2014
- Author(s)
  Kumagai-Takei N, Nishimura Y, Maeda M, Hayashi H, Matsuzaki H, Lee S, Kishimoto T, Fukuoka K, Nakano T, and Otsuki T
- Journal Title
  
  J Immunol Res
  
  Volume: 2014 Pages: 10-20
- DOI
  10.1155/2014/670140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860470, KAKENHI-PROJECT-25860471
[Journal Article] 【抗腫瘍免疫の抑制と活性化】アスベストによる抗腫瘍免疫の抑制2014
- Author(s)
  西村泰光, 武井直子, 松崎秀紀, 李順姫, 大槻剛巳
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 61 Pages: 585-91
- Data Source
  KAKENHI-PROJECT-24590770
[Journal Article] 珪酸曝露による免疫影響2014
- Author(s)
  松崎秀紀, 前田恵, 林宏明, 武井直子, 李順姫, 吉留敬, 草加勝康, 浦上更三, 西村泰光, 兵藤文則, 大槻剛巳
- Journal Title
  
  日本予防医学会雑誌
  
  Volume: 9 Pages: 1-8
- NAID
  40020166317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590770
[Journal Article] 【レギュラトリーT細胞の機能発現】制御性T細胞機能へのアスベスト曝露影響2014
- Author(s)
  西村泰光, 三浦由恵, 前田恵, 松崎秀紀, 李順姫, 武井直子, 大槻剛巳
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 62 Pages: 366-70
- Data Source
  KAKENHI-PROJECT-24590770
[Journal Article] アスベスト曝露によるTh1細胞機能の低下2014
- Author(s)
  西村泰光, 前田恵, 三浦由恵, 松崎秀紀, 李順姫, 武井直子, 大槻剛巳
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 62 Pages: 314-17
- NAID
  40020210778
- Data Source
  KAKENHI-PROJECT-24590770
[Journal Article] Silica exposure and altered regulation of autoimmunity2014
- Author(s)
  Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Maeda M, Chen Y, Kusaka M, Urakami K, Hayashi H, Fujimoto W, Nishimura Y, Otsuki T,
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 19 Issue: 5 Pages: 322-9
- DOI
  10.1007/s12199-014-0403-9
- NAID
  50009312838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
[Journal Article] Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2.2014
- Author(s)
  Maeda M, Chen Y, Hayashi H, Kumagai-Takei N, Matsuzaki H, Lee S, Nishimura Y, Otsuki T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 45 Issue: 6 Pages: 2522-2532
- DOI
  10.3892/ijo.2014.2682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24580494, KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
[Journal Article] Effect of asbestos exposure on differentiation of cytotoxic T lymphocytes in MLR of human PBMCs2013
- Author(s)
  Kumagai-takei N, Nishimura Y, Maeda M, Hayashi H, Matsuzaki H, Lee S, Hiratsuka J, Otsuki T
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 49(1) Issue: 1 Pages: 28-36
- DOI
  10.1165/rcmb.2012-0134oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25293267, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
[Journal Article] Exploration of biomarkers for asbestos exposure and occurrence of malignant mesothelioma based on the immunological effects of asbestos2013
- Author(s)
  Matsuzaki H, Lee S, Kumagai-Takei N, Hayashi H, Miura Y, Chen Y, Maeda M, Yamamoto S, Hatayama T, Nishimura Y, Otsuki T
- Journal Title
  
  J Postgenomics: Drug & Biomarker Dev
  
  Volume: S2 Issue: 02 Pages: 1-6
- DOI
  10.4172/2153-0602.s2-001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825
[Journal Article] Altered functions of alveolar macrophages and NK cells involved in asbestos-related diseases.2013
- Author(s)
  Nishimura, Y., Maeda, M.,Kumagai-Takei, N., Lee, S., Matsuzaki, H., Wada, Y., Nishiike-Wada, T., Iguchi, H., Otsuki, T.
- Journal Title
  
  Environ. Health Prev. Med.
  
  Volume: 18(3) Issue: 3 Pages: 198-204
- DOI
  10.1007/s12199-013-0333-y
- NAID
  10031175980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
[Journal Article] Resistance to asbestos-induced apoptosis with continuous exposure to crocidolite ona human T cell.2012
- Author(s)
  Maeda, M., Yamamoto, S., Chen, Y.,Kumagai-Takei, N., Hayashi, H., Matsuzaki, H., Lee, S., Hatayama, T., Miyahara, N., Katoh, M., Hiratsuka, J., Nishimura, Y., Otsuki, T.
- Journal Title
  
  Sci. Total Environ.
  
  Volume: 429 Pages: 174-182
- DOI
  10.1016/j.scitotenv.2012.04.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770
[Journal Article] Environmental factors producing autoimmune dysregulation-Chronic activation of T cells caused by silica exposure2012
- Author(s)
  Suni Lee
- Journal Title
  
  Immunobiology
  
  Volume: (Epub ahead of print) Issue: 7 Pages: 43-48
- DOI
  10.1016/j.imbio.2011.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790550, KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770
[Journal Article] Dysregulation of autoimmunity caused by silica exposure and alteration of Fas-mediated apoptosis in T lymphocytes derived from silicosis patients.2011
- Author(s)
  Otsuki T, et al
- Journal Title
  
  Int J Immunopath Pharmacol
  
  Volume: 24(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] 森林環境要素の免疫機能に及ぼす効果2011
- Author(s)
  大槻剛巳
- Journal Title
  
  森林セラピー
  
  Volume: Np. 5 Pages: 6-6
- Data Source
  KAKENHI-PROJECT-21659161
[Journal Article] Reductive alteration of the regulatory function of the CD4+CD25+ T cell fraction in silicosis patients.2010
- Author(s)
  Hayashi H, Miura Y, Maeda M, Murakami S, Kumagai N, Nishimura M, Kusaka M, Uragami K, Fujimoto W, Otsuki T.
- Journal Title
  
  Int J Immunopathol Pharmacol 23(4)
  
  Pages: 1099-1109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Dysregulation of the Immune System Caused by Silica and Asbestos.2010
- Author(s)
  Maeda M, Nishimura Y, Kumagai N, Hayashi H, Hatayama T, Katoh M, Miyahara N, Yamamoto S, Otsuki T.
- Journal Title
  
  J Immunotoxicol 7(4)
  
  Pages: 268-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] 珪肺症例における自己免疫異常の検出-血清可溶性インターロイキン2受容体と可溶性CD40リガンドの濃度の意義-2010
- Author(s)
  林宏明,西村泰光,前田恵,熊谷直子,村上周子,三浦由恵,草加勝康,浦上更三,大槻剛巳
- Journal Title
  
  日本職業・災害医学会会誌 58(2)
  
  Pages: 45-51
- NAID
  10029837869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] 珪酸・アスベストの免疫影響(ミニ特集:繊維・粒子状物質研究会(仙台)2010
- Author(s)
  熊谷直子,西村泰光,前田恵,林宏明,大槻剛巳
- Journal Title
  
  日本衛生学会誌 64(4)
  
  Pages: 93-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] The biological effects of negatively-charged indoor aire conditions2009
- Author(s)
  Otsuki T, Takahashi K, Mase A, Kawado T, Kotani M, Maeda M, Murakami S, Kumagai N, Hayashi H, Chen Y, Nishimura Y, Miura Y, Shirahama T, Yoshimatsu M, Morimoto K.
- Journal Title
  
  Kawasaki Med J
  
  Volume: 35(3) Pages: 205-214
- NAID
  110007338961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659161
[Journal Article] Cytokine alteration and speculated immunological patho physiology in silicosis and asbestos-related diseases.2009
- Author(s)
  Murakami S, Nishimura Y, Maeda M, Kumagai N, Hayashi H, Chen Y, Kusaka K, Kishimoto T, Otsuki T.
- Journal Title
  
  Environ Health Prev Med 14(4)
  
  Pages: 216-222
- NAID
  10026958932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Nova Science Publishers, Inc.2009
- Author(s)
  Otsuki T, et al.
- Journal Title
  
  Immunological effects of Asbestos.In Asbestos : Risks, Environment and Impact.Eds : Antonio Soto and Gael Salazar, ISBN 978-1-60692-053-4, (C) 2009
  
  Pages: 185-193
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Establishment of Negatively-charged Indoor Air Conditions and their Biological Effects2009
- Author(s)
  Otsuki T, Takahashi K, Mase A, Kawado T, Kotani M, Nishimura Y, Maeda M, Murakami S, Kumagai N, Hayashi H, Chne Y, Miura Y, Shirahama T, Yoshimatsu M, Morimoto K.
- Journal Title
  
  In Buildings and the Environment. Authors/Editors : Jonas Nemecek and Patrik Schulz. Pub.Date : 2009 4th Quarter ISBN : 978-1-60876-128-9(C)2009 Nova Science Publishers, Inc. 2009
  
  Pages: 201-214
- Data Source
  KAKENHI-PROJECT-21659161
[Journal Article] Impairment in cytotoxicity and expression of NK-cell activating receptors on human NK cells following exposure to asbestos fibers.2009
- Author(s)
  Nishimura Y, Miura Y, Maeda M, Kumagai N, Murakami S, Hayashi H, Fukuoka K, Nakano T, Otsuki T.
- Journal Title
  
  Int J Immunopathol Pharmacol 22(3)
  
  Pages: 579-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] マイナス荷電粒子優位な室内空気環境の生体影響の観察-精神・神経・内分泌・免疫ネットワークへの影響について-2009
- Author(s)
  西村泰光, 高橋一聡, 間瀬昭則, 河戸隆, 小谷宗男, 阿見和久, 松島弘樹, 白濱毅, 吉松道晴, 前田恵, 村上周子, 林宏明, 熊谷直子, 陳〓, 三浦由恵, 森本兼曩, 大槻剛巳
- Journal Title
  
  日本職業・環境アレルギー学会雑誌
  
  Volume: 16(2) Pages: 15-24
- NAID
  40016794942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659161
[Journal Article] The biological effects of negatively-charged indoor sire conditions2009
- Author(s)
  Otsuki T, et al
- Journal Title
  
  Kawasaki Med J 35
  
  Pages: 205-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659161
[Journal Article] Is soluble CD40 ligand an indicator of immunopathological disturbance in silicosis patients?2009
- Author(s)
  Hayashi H, Nishimura Y, Maeda M, Murakami S, Kumagai N, ChenY, Kusaka M, Uragami K, Fujimoto W, Otsuki T.
- Journal Title
  
  Kawasaki Med J 35(2)
  
  Pages: 129-138
- NAID
  110007150517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Decrease in phosphorylation of ERK following decreased expression of NK-cell activating receptors in human NK cell line exposed to asbestos.2009
- Author(s)
  Nishimura Y, Maeda M, Kumagai N, Hayashi H, Miura Y, Otsuki T.
- Journal Title
  
  Int J Immunopathol Pharmacol 22(4)
  
  Pages: 879-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Two weeks of permanence in negatively-charged air conditions causes alteration of natural killer cell function2009
- Author(s)
  Takahashi K, Otsuki T, Mase A, Kawado T, Kotani M, Nishimura Y, Maeda M, Murakami S, Kumagai N, Hayashi H, Chen Y, Shirahama T, Miura Y, Morimoto K.
- Journal Title
  
  Int J Immunopathol Pharmacol
  
  Volume: 22(2) Pages: 333-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659161
[Journal Article] Soluble interleukin-2 receptor as an indicator of immunological disturbance found in silicosis patients2009
- Author(s)
  Hayashi H, Maeda M, Murakami S, Kumagai N, Chen Y, Hatayama T, Katoh M, Miyahara N, Yamamoto S, Yoshida Y, Nishimura Y, Kusaka M, Fujimoto W, Otsuki T.
- Journal Title
  
  Int J Imminopathol Pharmacol 22(1)
  
  Pages: 53-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Immunological alterations found in mesothelioma patients and their experimental evidences2008
- Author(s)
  Miura Y, Nishimura Y, Maeda M, Murakami S, Hayashi H, Fukuoka K, Kishimoto T, Nakano T, Otsuki T.
- Journal Title
  
  Environ Health Prev Med 13
  
  Pages: 55-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] 珪肺症例CD4+25+分画における活性化T細胞の混入と制御性T細胞早期細胞死の可能性2008
- Author(s)
  林宏明, 三浦由恵, 前田恵, 村上周子, 熊谷直子, 西村泰光, 草加勝康, 大槻剛巳.
- Journal Title
  
  日本職業・環境アレルギー学会雑誌 15
  
  Pages: 42-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Immunological alterations found in mesothelioma patients and their experimental evidences2008
- Author(s)
  Miura Y, Nishimura Y, Maeda M, Murakami S, Hayashi H, Fukuoka K, Kishimoto T, Nakano T, Otsuki T
- Journal Title
  
  Environ Health Prev Med 13
  
  Pages: 55-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659153
[Journal Article] Immunological changes in mesothelioma patients and their experimental detection2008
- Author(s)
  Maeda M, Miura Y, Nishimura Y, Murakami S, Hayashi H, Kuiagai N, Hatayama T, Katoh M, Miyahara N, Yamamoto S, Fukuoka K, KishimotoT, Nakano T, Otsuki T.
- Journal Title
  
  Clin Med : Circ, Resp Pulm Med 2
  
  Pages: 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659153
[Journal Article] Immunological changes in mesothelioma patients and their experimental detection2008
- Author(s)
  Maeda M, Miura Y, Nishimua Y, Murakami S, Hayashi H, Kumagai N, Hatayama T, Katoh M, Miyahara N, Yamamoto S, Fukuoka K, Kishimoto T, Nakano T, Otsuki T.
- Journal Title
  
  Clin Med : Circ, Resp Pulm Med 2
  
  Pages: 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] 珪肺症例CD4+25+分画における活性化T細胞の混入と制御性T細胞早期細胞死の可能性2008
- Author(s)
  林宏明, 三浦由恵, 前田恵, 村上周子, 熊谷直子, 西村泰光, 草加勝康, 大槻剛巳
- Journal Title
  
  日本職業・環境アレルギー学会雑誌 15
  
  Pages: 42-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659153
[Journal Article] LONG-LASTING PRODUCTION OF TGF-BETA1 BY ALVEOIAR MACROPHACES EXPOSED TO LOW DOSES OF ASBESTOS WITHOUT APOPTOSLS.2007
- Author(s)
  NISHIMURA Y, NISHIEE-WADA T, WADA Y, MIURA OTSUKI T, IGUCHI H
- Journal Title
  
  INT JIMMUNOPATHOL PHARMACOL 20(4)
  
  Pages: 661-667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Immunological effects of silica and asbestos2007
- Author(s)
  Otsuki T, Maeda M, Murakami S, Hayashi H, Miura Y, Kusaka M, Nakano T, Fukuoka K, Kishimoto T, Hyodoh F, Ueki A, Nishimura Y.
- Journal Title
  
  Cell Mol Immnol 4
  
  Pages: 261-268
- NAID
  10029363262
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] IMMUNOTOXEOLOGICAL RESEARCHES AND PREVENTIVE MEDICINE. FOREWORD-THE RREPORT FROM THE 13TH ANNUAL MEETING OF THE JAPANESE SOCIETY OF IMMUNOTOXICOLOGY (JSIT 2006).2007
- Author(s)
  OTSUKI T
- Journal Title
  
  ENVIRONHEALTHPREVMED 12(4)
  
  Pages: 151-152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] KEYNOTE LECTURE IN THE 13TH JAPANESE SOCIETY OF IMMUNOTOXICOLOGY(JSIT 2006)- PATHOPHYSTOLOGICAL DEVELOPMENT AND IMMUNOTOXICOLOGY WHAT WE HAVE FOUND FROM THE RESEARCHES RELATED TO THE SILICAAND SILICATE SUCHASASBESTOS-.2007
- Author(s)
  OTSUKI T, MIURAY, HYODOH F, MAMAM, HAYASHI H, DONGM KATSUYAMA H, TOMITA M, UEKI A, NISHIMURA Y.
- Journal Title
  
  KAWASAKE MED J 33(3)
  
  Pages: 165-179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Immunological effects of silica and asbestos2007
- Author(s)
  Otsuki T, Maeda M, Murakami S, Hayashi H, Miura Y, Kusaka M, Nakano T, Fukuoka K, Kishimoto T, Hyodoh F, Ueki A, Nishimura Y.
- Journal Title
  
  Cell Mol Immnol 4
  
  Pages: 261-268
- NAID
  10029363262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659153
[Journal Article] IMMUNOLOGICAL EFFECTS OF SIT JCAANDASBESTOS.2007
- Author(s)
  OTSUKI T, MAEDA M, MURAKAMI S, HAYASHI H, MIURA Y, KUSAKA M, NAKANO T, FUKUOKAK, KESHIMOTO T, HYODOH F, UEKI A, NESHMURAY.
- Journal Title
  
  CELLMOLIMMNOL 4(4)
  
  Pages: 261-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] KEYNOTE LECTURE IN THE 13TH JAPANESE SOCIETY OF IMMUNOTOXICOLOGY(JSIT 2006)-PATHOPHYSIOLOGICAL DEVELOPMENT AND IMMUNOTOXECOLOGY WHAT WE HAVE FOUND FROM THE RESEARCHES RELATED TO THE SIT ICAAND STI ICATE SUCHASASBFSTOS-.2007
- Author(s)
  OTSUKI, T, MEURAY, MAEDAM, HAYASHI H, DONGM, NISHMURAY.
- Journal Title
  
  ENVIRONHEALTHPREVMED 12(4)
  
  Pages: 153-164
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Expression of the T cell receptor Vβ repertoire in a human T cell resistant to asbestos-induced apoptosis and peripheral blood T cells from patients with silica and asbestos-related diseases.2006
- Author(s)
  Nishimura Y, Miura Y, Maeda M, Hayashi H, Dong M, Katsuyama H, Tomita M, Hyodoh F, Uesaka A, Kuribayashi K, Fukuoka K, Nakano T, Kishimoto T, Otsuki T.
- Journal Title
  
  Int J Immunopathol Pharmacol 19(4)
  
  Pages: 795-805
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Involvement of IL-10 and Bcl-2 in resistance against an asbestos-induced apoptosis of T cells.2006
- Author(s)
  Miura Y, Nishimura Y, Katsuyama H, Maeda M, Hayashi H, Dong M, Hyodoh F, Tomita M, Mastuo Y, Uesaka A, Kuribayashi K, Nakano T, Kishimoto T, Otsuki T
- Journal Title
  
  Apoptosis 11(10)
  
  Pages: 1825-35
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Asbestos-related carcinogenesis and immunological effects (Focus lecture 1)2006
- Author(s)
  Otsuki T, Miura Y, Maeda M, Hayashi H, Dong M, Nishimura Y, Tomita M, Katsuyama H.
- Journal Title
  
  Biomed Res Trace Elements 17(s2)
  
  Pages: 9-103
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Reduced function of CD4+25+ regulatory T cell fraction in silicosis patients.2006
- Author(s)
  Wu P, Miura Y, Hyodoh F, Nishimura Y, Hatayama T, Hatada S, Sakaguchi H, Kusaka M, Katsuyama H, Tomita M, Otsuki T.
- Journal Title
  
  Int J Immunopathol Pharmacol 19(2)
  
  Pages: 357-68
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] 珪肺症と石綿関連疾患における抹消血T細胞受容体Vβレパトアの解析.2006
- Author(s)
  大槻剛巳, 西村泰光, 三浦由恵, 兵藤文則, 勝山博信, 上坂亜由子, 栗林康造, 中野孝司, 草加勝康, 岸本卓巳.
- Journal Title
  
  日本職業・災害医学会会誌 51
  
  Pages: 66-71
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Alterations of Fas and Fas-related molecules in patients with silicosis. 〔Review article〕2006
- Author(s)
  Otsuki T, Miura Y, Nishimura Y, Hyodoh F, Takata A, Kusaka M, Katsuyama H, Tomita M, Ueki A, Kishimoto T
- Journal Title
  
  Exp Biol Med (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Alterations of Fas and Fas-related molecules in patients with silicosis. [Review article]2006
- Author(s)
  Otsuki T, Miura Y, Nishimura Y, Hyodoh F, Takata A, Kusaka M, Katsuyama H, Tomita M, Ueki A, Kishimoto T
- Journal Title
  
  Exp Biol Med 231(5)
  
  Pages: 522-33
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] 医学のあゆみアスベストの健康障害-発癌予防分子標的の検索2006
- Author(s)
  大槻剛巳
- Journal Title
  
  医学のあゆみ 216(In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Detection, epitope-mapping, and function of anti-Fas autoantibody in patients with silicosis.2005
- Author(s)
  Takata-Tomokuni A, Ueki A, Shiwa M, Isozaki Y, Hatayama T, Katsuyama H, Hyodoh F, Fujimoto W, Ueki H, Kusaka M, Arikuni H, Otsuki T
- Journal Title
  
  Immunology 116
  
  Pages: 21-29
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Inhibitory effects of anti-oxidants on apoptosis of a human polyclonal T cell line, MT-2, induced by an asbestos, chrysotile-A.2005
- Author(s)
  Hyodoh F, Takata-Tomokuni A, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Katsuyama H, Matsuo Y, Otsuki T
- Journal Title
  
  Scand J Immunol 61
  
  Pages: 442-448
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Inhibitory effects of anti-oxidants on apoptosis of a human palyclonal T cell line, MT-2, induced by an asbestos, chrysotile-A2005
- Author(s)
  Hyodoh F, Takata-Tomokuni A, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Katsuyama H, Matsuo Y, Otsuki T.
- Journal Title
  
  Scand J Immunal 61
  
  Pages: 442-448
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Induction of CD69 antigen expression in peripheral blood mononuclear cells on exposure to silica, but not by asbestos/chrysotile-A2005
- Author(s)
  Wu P, Hyodoh F, Hatayama T, Sakaguchi H, Hatada S, Miura Y, Takata-Tomokuni A, Katsuyama H, Otsuki T
- Journal Title
  
  Immunol Lett 98
  
  Pages: 145-152
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Induction of CD69 antigen expression in peripheral blood mononuclear cells on exposure to silica, but not by asbestos/chrysotile-A.2005
- Author(s)
  Wu P, Hyodoh F, Hatayama T, Sakaguchi H, Hatada S, Miura Y, Takata-Tomokuni A, Katsuyama H, Otsuki T.
- Journal Title
  
  Immunol Lett 98(1)
  
  Pages: 145-152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] The inhibitory effect of dlbutyryl cyclicAMP on docosahexaenoic acid-induced apoptosis involves phosphatidylinositol-3 kinase pathway in HL-60 cells.2005
- Author(s)
  Miura Y, Murata Y, Utsumi K, Takahata K, Tada M, Otsuki T.
- Journal Title
  
  Environ Health Prev Med 10
  
  Pages: 184-189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例に検出されるFasとその関連分子の異常2005
- Author(s)
  高田晶子, 三浦由恵, 兵藤文則, 勝山博信, 植木絢子, 大槻剛巳
- Journal Title
  
  日本衛生学雑誌 60(1)
  
  Pages: 30-37
- NAID
  10014312270
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Inhibitory effects of anti-oxidants on apoptosis of a human polyclonal T cell line, MT-2, induced by an asbestos, chrysotile-A2005
- Author(s)
  Hyodoh F, Takata-Tomokuni A, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Katsuyama H, Matsuo Y, Otsuki T
- Journal Title
  
  Scand J Immunol 61
  
  Pages: 442-448
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Detection, epitope-mapping, and function of anti-Fas autoantibody in patients with silicosis.2005
- Author(s)
  Takata-Tomokuni A, Ueki A, Shiwa M, Isozaki Y, Hatayama T, Katsuyama H, Hyodoh F, Fujimoto W, Ueki I, Kusaka M, Arikuni H, Otsuki T.
- Journal Title
  
  Immunology 116
  
  Pages: 21-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] The inhibitory effect of dibutyryl cyclicAMP on docosahexaenoic acid-induced apoptosis involves phoshatidylinositol-3 kinase pathway in HL-60 cells.2005
- Author(s)
  Miura Y, Murata Y, Utsumi K, Takahata K, Tada M, Otsuki T
- Journal Title
  
  Environ Health Prev Med 10
  
  Pages: 184-189
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] アスベストのすべて2005
- Author(s)
  三浦由恵, 西村泰光, 兵藤文則, 大槻剛巳
- Journal Title
  
  川崎医学会誌 31
  
  Pages: 121-126
- NAID
  110004675869
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Induction of CD69 antigen expression in peripheral blood mononuclear cells on exposure to silica, but not by asbestos/chrysotile-A2005
- Author(s)
  Wu P, Hyodoh F, Hatayama T, Sakaguchi H, Hatada S, Miura Y, Takata-Tomokuni A, Katsuyaaa H, Otsuki T
- Journal Title
  
  Immunol Lett 98
  
  Pages: 145-152
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Detection, epitope-mapping, and function of anti-Fas autoantibody in patients with silicosis.2005
- Author(s)
  Takata-Tomokuni A, Ueki A, Shiwa M, Ixozaki Y, Hatayama T, Katsuyama H, Hyodoh F, Fujimoto W, Ueki H, Kusaka M, Arikuni H, Otsuki T
- Journal Title
  
  Immunology 116
  
  Pages: 21-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例に検出されるFasとその関連分子の異常2005
- Author(s)
  高田晶子, 三浦由恵, 兵藤文則, 勝山博信, 植木絢子, 大槻剛巳
- Journal Title
  
  日本衛生学雑誌 60
  
  Pages: 30-37
- NAID
  10014312270
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] The inhibitory effect of dibutyryl cyclicAMP on docosahexaenoic acid-induced apoptosis involves phosphatidylinositol-3 kinase pathway in HL-60 cells2005
- Author(s)
  Miura Y, Murata Y, Utsumi K, Takahata K, Tada M, Otsuki T
- Journal Title
  
  Environ Health Prey Med 10
  
  Pages: 184-189
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症例T細胞における膜Fas発現2005
- Author(s)
  大槻剛巳, 高田晶子, 植木絢子, 三浦由恵, 西村泰光, 草加勝康, 勝山博信
- Journal Title
  
  臨床環境医学 14
  
  Pages: 119-127
- NAID
  10020417134
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Asbestosによるリンパ球細胞死の検討2004
- Author(s)
  大槻剛巳, 三浦由恵, 高田晶子, 兵藤文則
- Journal Title
  
  ImunoTox Let 9
  
  Pages: 7-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例で認められた抗Fas自己抗体の機能解析2004
- Author(s)
  高田-友国晶子, 植木絢子, 三浦由恵, 草加勝康, 勝山博信, 大槻剛巳
- Journal Title
  
  臨床環境医学 13(2)(印刷中)
- NAID
  10029423582
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Regulatory T cells in silicosis patients2004
- Author(s)
  Hyodoh, F., Takata, A., Otsuki, T.
- Journal Title
  
  Jpn.J.Hyg. 59(1)
  
  Pages: 158-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590491
[Journal Article] Expression of PGP9.5 (Protein Gene Product 9.5)/UCHL-1 (Ubiquitin-C-terminal hydrolase 1) in human myeloma cells.2004
- Author(s)
  Otsuki T, Yata K, Takata-Tomokuni A, Hyodoh F, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Tsujioka T, Sato Y, Murakami H, Sadahira Y, Sugihara T.
- Journal Title
  
  Br J Haematol 127
  
  Pages: 292-298
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例で認められた抗がFas自己抗体の機能解析2004
- Author(s)
  高田-友国晶子, 植木絢子, 三浦由恵, 草加勝康, 勝山博信, 大槻剛巳
- Journal Title
  
  臨床環境医学 13
  
  Pages: 102-109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Effects of genetic and nutritional factors on bone mineral density in young adults.2004
- Author(s)
  Otsuki T, Sakaguchi H, Hatta E, Hatayama T, Hatada S, Miura Y, Takata-Tomokuni A, Hyodoh F, Tomomitsu T, Fukunaga M, Katsuyama H.
- Journal Title
  
  Int J Mol Med 14(4)
  
  Pages: 669-676
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Secretory Ig A in saliva and academic stress.2004
- Author(s)
  Otsuki T, Sakaguchi H, Hatayama T, Takata A, Hyodoh F, Tsujita S, Ueki A, Morimoto K
- Journal Title
  
  Int J Immunopathol Pharmaco 17
  
  Pages: 45-48
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Secretory Ig A in saliva and academic stress.2004
- Author(s)
  Otsuki T, Sakaguchi H, Hatayama T, Takata A, Hyodoh F, Tsujita S, Ueki A, Morimoto K.
- Journal Title
  
  Int J Immunopathol Pharmacol 17(2S)
  
  Pages: 45-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Alterations of Fas and Fas-related molecules in patients with silicosis.
- Author(s)
  Otsuki T, Miura Y, Nishimura Y, Hyodoh F, Takata A, Kusaka M, Katsuyama H, Tomita M, Ueki, A, Kashimoto T
- Journal Title
  
  Exp Biol Med(in press) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Immunological alterations found in mesothelioma patients and their experimental evidences.
- Author(s)
  Miura Y, Nislrimura Y, Maeda M, Murakami S, Hayashi H, Fukuoka K, Kishimoto T, Nakano T, Otsuki T.
- Journal Title
  
  Environ Health Prev Med (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659153
[Journal Article] Immunological alterations found in mesothelioma patients and their experimental evidences.
- Author(s)
  Miura Y, Nishimura Y, Maeda M, Murakami S, Hayashi H, Fukuoka K, Kishimoto T, Nakano T, Otsuki T.
- Journal Title
  
  Environ Health Prev Med (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Immunological alterations found in mesothelioma patients and their experimental evidences
- Author(s)
  Miura Y, Nishimura Y, Maeda M, Murakami S, Hayashi H, Fukuoka K, Kishimoto T, Nakano T, Otsuki T.
- Journal Title
  
  Environ Health Prev Med (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Induction of CD69 antigen expression in peripheral blood mononuclear cells on exposure to silica, but not by asbestos/chrysotile-A.
- Author(s)
  Wu P, Hyodoh F, Hatayama T, Sakaguchi H, Hatada S, Miura Y, Takata-Tomokuni A, Katsuyama H, Otsuki T
- Journal Title
  
  Immunol Lett (In press)
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Dysregulation of autoimmunity caused by silica exposure and alteration of Fas-mediated apoptosis in T lymphocytes derived from silicosis patients.
- Author(s)
  Otsuki T, Hayashi H, Nishimura Y, Hyodo F, Maeda M, Kumagai N, Miura Y, Kusaka M, Urakami K
- Journal Title
  
  Int J Immunopath Pharmacol 24(1)(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Suppressive effect of asbestos on cytotoxicity of human NK cells.
- Author(s)
  Nishimura Y, Kumagai N, Maeda M, Hayashi H, Fukuoka K, nakano T, Miura Y, HIratsuka J, Otsuki T.
- Journal Title
  
  Int J Immunopath Pharmacol 24(1)(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] Decreased CXCR3 expression in CD4+ T cells exposed to asbestos or derived from asbestos-exposed patients.
- Author(s)
  Maeda M, Nishimura Y, Hayashi H, Kumagai N, Chen Y, Murakami S, Miura Y, Hiratsuka J, Kishimoto T, Otsuki T.
- Journal Title
  
  Am J Resp Cell Mol Biol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Journal Article] NEGATIVELY-CHARGED AIR CONDITIONS AND RESPONSES OF THE HUMANPSYCHO-NEURO-ENDOCRINO-IMMUNE NETWORK.
- Author(s)
  TAKAHASHI K, OTSUKI T, MASE A, KAWADO T, KOTANI M, AMI K, MATSUSHIMA H, NESHMURA Y, MIURA Y, MURAKAMI S, MAEDA M, HAYASHI H, KUMAGAI N, SHIRAHAMA T, YOSHIMATSU M, MORIMOTO K
- Journal Title
  
  ENVIRONINT (IN PRESS)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390186
[Journal Article] Reduction of CXCR3 in an in vitro model of continuous asbestos exposure on a human T-cell line, MT-2.
- Author(s)
  Maeda M, Nishimura Y, Hayashi H, Kumagai N, Chen Y, Murakami S, Miura Y, Hiratsuka J, Kishimoto T, Otsuki T.
- Journal Title
  
  Am J Resp Cell Mol Biol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390178
[Patent] 自己免疫異常の検査方法2020
- Inventor(s)
  李順姫, 大槻剛巳
- Industrial Property Rights Holder
  李順姫, 大槻剛巳
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-20K10437
[Patent] 自己免疫異常の検査方法2017
- Inventor(s)
  大槻剛巳、西村泰光、李順姫
- Industrial Property Rights Holder
  川崎医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-192501
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K09171
[Presentation] 主成分分析による悪性中皮腫のニボルマブ治療効果に関わる免疫動態の評価2022
- Author(s)
  西村泰光, 李順姫, 武井直子, 伊藤達男, 上月稔幸, 藤本伸一, 大槻剛巳
- Organizer
  第92回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] 悪性中皮腫患者末梢血の免疫学的特徴とニボルマブ治療効果との関連2021
- Author(s)
  西村泰光, 李順姫, 武井直子, 伊藤達男, 藤本伸一, 上月稔幸, 大槻剛巳
- Organizer
  第28回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] トランスクリプトーム解析による石綿曝露に共通する細胞傷害性T細胞の遺伝子発現変動および石綿種間での差異の探索2021
- Author(s)
  西村泰光, 武井直子, 李順姫, 伊藤達男, 大槻剛巳
- Organizer
  第48回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] 珪酸曝露によるヒト末梢血単核球における遺伝子発現およびサイトカイン分泌の解析2021
- Author(s)
  李順姫, 西村泰光, 大槻剛巳
- Organizer
  第28回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K10437
[Presentation] チタン酸ナノシートの毒性機序における細胞内Ca2+増加を介したリソソーム制御不全2021
- Author(s)
  西村泰光, 吉岡大輔, 武井直子, 李順姫, 吉留敬, 伊藤達男, 大槻剛巳
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] 悪性中皮腫患者におけるニボルマブ投与前後の包括的免疫機能解析2021
- Author(s)
  西村泰光, 李順姫, 武井直子, 伊藤達男, 藤本伸一, 上月稔幸, 大槻剛巳
- Organizer
  第2回日本石綿・中皮腫学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] The Toxicity of Titanate Nanosheets Attributed to Out-of-Control Function of Lysosomes Caused by Increase in Intracellular Calcium Ions2020
- Author(s)
  Nishimura Y, Yoshioka D, Kumagai-Takei N, Suni L, Ito T, Otsuki T
- Organizer
  Society of Toxicology (SOT) 60th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] Titanate nanosheets cause vacuolar ATPase-dependent apoptosis of human monocytes through lysosomal toxicity not related with augmented autophagy2020
- Author(s)
  Y. Nishimura, D. Yoishioka, N. Kumagai-Takei, S. Lee, K. Yoshitome, and T. Otsuki
- Organizer
  Society of Toxicology (SOT) 59th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] チタン酸ナノシートの毒性機序におけるリソソーム由来Ca2+シグナリングの役割2020
- Author(s)
  西村泰光, 吉岡大輔, 武井直子, 李順姫, 吉留敬, 伊藤達雄, 大槻剛巳
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] 石綿曝露によるCTL分化抑制における補助刺激分子の役割2020
- Author(s)
  武井直子、西村泰光、吉留敬、李順姫、伊藤達男、大槻剛巳
- Organizer
  第27回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] 石綿曝露下CTL分化抑制時の補助刺激分子の役割2020
- Author(s)
  武井直子、西村泰光、李順姫、吉留敬、伊藤達男、大槻剛巳
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] ヒトCD8+T細胞株において石綿長期曝露で発現変動する転写産物の網羅的探索2020
- Author(s)
  西村泰光, 武井直子, 李順姫, 吉留敬, 伊藤達男, 大槻剛巳
- Organizer
  第93回日本産業衛生学会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] 石綿継続曝露T細胞における石綿誘導性細胞死忌避メカニズムの探索2020
- Author(s)
  李順姫、山本祥子、松﨑秀紀、幡山圭代、武井直子、吉留敬、伊藤達男、西村泰光、大槻剛巳
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] 長期石綿曝露ヒトTリンパ球細胞株のトランスクリプトーム解析2020
- Author(s)
  西村泰光、武井直子、李順姫、吉留敬、伊藤達男、大槻剛巳
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] 石綿曝露下CTL分化抑制時の補助刺激分子の役割2020
- Author(s)
  武井直子、西村泰光、李順姫、吉留敬、伊藤達男、大槻剛巳．
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] 石綿長期曝露ヒト制御性T細胞モデル株におけるMM7発現の更新と機能解析2020
- Author(s)
  李順姫、山本祥子、幡山圭代、伊藤達男、武井直子、吉留敬、西村泰光、大槻剛巳
- Organizer
  第27回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] チタン酸ナノシートの毒性機序におけるTRPMLチャンネルの関与2019
- Author(s)
  西村泰光, 吉岡大輔, 李順姫, 武井直子, 吉留敬, 伊藤達雄, 大槻剛巳
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] チタン酸ナノシートの細胞毒性における小胞酸性化と液胞型ATPアーゼ依存性2019
- Author(s)
  西村泰光, 吉岡大輔, 武井直子, 李順姫, 吉留敬, 大槻剛巳
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] Immunological screening devices for patients with malignant mesothelioma as well as people exposure to asbestos2019
- Author(s)
  Nishimura Y. Kumagai-Takei N, Lee S, Matsuzaki H, Yoshitome K, Kishimoto T, Fukuoka K, Tabata C, Nakano T, Otsuki T.
- Organizer
  The 18th International Conference of the Pacific Basin Consortium for Environment and Health (PBC) titled Assessing and Mitigating Environmental Exposures in Early Life
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] 珪酸曝露下の免疫細胞におけるTLR刺激応答と自己免疫疾患関連分子の探索2019
- Author(s)
  李順姫、山本祥子、幡山圭代、松﨑秀紀、武井奈子、吉留敬、西村泰光、大槻剛巳
- Organizer
  第89回日本衛生学会
- Data Source
  KAKENHI-PROJECT-17K09171
[Presentation] 石綿曝露と免疫機能、悪性中皮腫の免疫バイオマーカー．シンポジウム「免疫毒性から見た炎症と病態2019
- Author(s)
  西村泰光、大槻剛巳
- Organizer
  第26回日本免疫毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] ヒト単球へのチタン酸ナノシートのv-ATPase依存的リソソーム毒性2019
- Author(s)
  西村泰光、吉岡大輔、武井直子、李順姫、吉留敬、大槻剛巳
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] IL-15に注目したCTL分化に及ぼす石綿曝露影響の機序解析2019
- Author(s)
  武井直子、西村泰光、李順姫、吉留敬、大槻剛巳．
- Organizer
  第26回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] Comprehensive analysis for immunological characteristics of patients with malignant mesothelioma and diffuse pleural thickening2019
- Author(s)
  Nishimura Y, Lee S, Kumagai-Takei N, Mastuzaki H, Yoshitome K, Okamoto K, Kishimoto T, Otsuki T
- Organizer
  The XV International Congress of Toxicology (ICTXV)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] ヒトCD8+T細胞株における石綿曝露日数依存的IFN-γ mRNAレベルの漸減2019
- Author(s)
  西村泰光、武井直子、李順姫、吉留敬、大槻剛巳
- Organizer
  第92回日本産業衛生学会
- Data Source
  KAKENHI-PROJECT-19H03892
[Presentation] IL-15-induced recovery of suppressed proliferation and granzyme B level of CTL upon exposure to asbestos during MLR2019
- Author(s)
  Kumagai-Takei N, Nishimura Y, Otsuki T.
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] CD4+ T Cell-Derived Factors Prevent Asbestos-Caused Suppression of Mesothelial Cell Growth2019
- Author(s)
  Nishimura Y, Kumagai-Takei N, Lee S, Yoshitome K, Otsuki T
- Organizer
  The 58th Annual Meeting of the Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] 活性化CD4+Tリンパ球由来因子による石綿曝露下の中皮細胞増殖抑制への干渉2019
- Author(s)
  西村泰光、武井直子、李順姫、吉留敬、大槻剛巳
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] 珪肺症と自己免疫疾患2019
- Author(s)
  李順姫、武井直子、吉留敬、西村泰光、大槻剛巳
- Organizer
  第46回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09171
[Presentation] 石綿曝露下CTL分化抑制時の細胞増殖と granzyme B産生に対するIL-15の影響2019
- Author(s)
  武井直子、西村泰光、松﨑秀紀、李順姫、吉留敬、大槻剛巳
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] チタン酸ナノシート曝露によるヒト単球培養時のオートファジー関連遺伝子発現量変化2018
- Author(s)
  西村泰光、吉岡大輔、武井直子、李順姫、吉留敬、大槻剛巳
- Organizer
  第25回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] The Functional Analysis of Human CD8+ T Cell Line with Long-Term Exposure to Chrysotile Asbestos Fibers2018
- Author(s)
  Kumagai-Takei N. Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T
- Organizer
  The 57th Annual Meeting of the Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] ヒト CD8+T 細胞株を用いて作成した石綿曝露亜株の機能解析2018
- Author(s)
  武井直子、西村泰光、松﨑秀紀、李順姫、吉留敬、大槻剛巳
- Organizer
  第25回石綿・中皮腫研究会
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] Difference in Immunological Characteristics between Patients with Malignant Mesothelioma and Diffuse Pleural Thickening2018
- Author(s)
  Yasumitsu Nishimura, Suni Lee, Naoko Kumagai-Takei, Hidenori Matsuzaki, Kei Yoshitome, Takemi Otsuki
- Organizer
  The 57th Annual Meeting of the Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Immune-suppressed characteristics with increased Treg marker and decreased perforinexpression by CTL in patients with mesothelioma compared with diffuse pleural thickening2018
- Author(s)
  Nishimura Y, Kumagai-Takei N, Otsuki T
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] The functional analysis of human CD8+ T cell line with long-term exposure to chrysotile asbestos fibers2018
- Author(s)
  Kumagai-Takei N. Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T.
- Organizer
  The 57thAnnual Meeting of the Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] Search for biomarkers of asbestos exposure and asbestos-induced cancers in investigations of the immunological effects of asbestos2018
- Author(s)
  Otsuki T, Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Nishimura Y
- Organizer
  ICOH (International Congress on Occupational Health) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Effects of IL-15 addition on the suppressed induction of CTL upon exposure to asbestos2018
- Author(s)
  Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T
- Organizer
  ICOH (International Congress on Occupational Health) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Augmented prioliferation of mesothelial cells caused by secretory factors derived from immune cells upon exposure to asbestos2018
- Author(s)
  Nishimura Y, Maki Y, Kumagai-Takei N, Lee S, Matsuzaki H, Yosahitome K, Otsuki T
- Organizer
  ICOH (International Congress on Occupational Health) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Nanotoxicity of titanium nanosheets for human immune cells2018
- Author(s)
  Nishimura Y, Yoshioka D, Kumagai-Takei N, Matsuzaki H, Lee S, Yoshitome K, Otsuki T
- Organizer
  ICOH (International Congress on Occupational Health) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] チタン酸ナノシート曝露後の単球におけるアポトーシスの機序解析，リソソーム・オートファジー機能との関連2018
- Author(s)
  西村泰光、吉岡大輔、武井直子、吉留敬、大槻剛巳
- Organizer
  メタルバイオサイエンス研究会2018
- Data Source
  KAKENHI-PROJECT-18K19714
[Presentation] Scores predictive for asbestos exposure, malignant mesothelioma and pleural plaque on the basis of comprehensive immunological analysis2018
- Author(s)
  Nishimura Y, Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Nakno T, Kishimoto T, Otsuki T
- Organizer
  ICOH (International Congress on Occupational Health) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Induction of IL-17 production from human peripheral blood CD4+ cells by asbestos exposure2018
- Author(s)
  Otsuki T, Maeda M, Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Nishimura Y
- Organizer
  ICOH (International Congress on Occupational Health) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Effet of long-term exposure to asbestos on functional properties of human CD8+ T cell line2018
- Author(s)
  Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T
- Organizer
  ICOH (International Congress on Occupational Health) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Apoptosis of monocytes with giant vacuoles related to disruption in endosomal pathway caused by titanate nanosheets2017
- Author(s)
  Nishimura Y, Kumagai-Takei N, Lee S, Matsuzaki H, Yoshitome K, Otsuki T
- Organizer
  The British Society for Immunology Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15245
[Presentation] Increased Proliferation of Mesothelial Cells under the Influence of Asbestos-Exposed Peripheral Blood Mononuclear Cells2017
- Author(s)
  Nishimura Y. Maki Y, Tooyoka S, Kumagai-Takei N, Lee S, Matsuzaki H, Otsuki T
- Organizer
  The 56th Annual Meeting of the Society of Toxicology
- Place of Presentation
  Baltimore Convention Center, Baltimore, USA
- Year and Date
  2017-03-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] アスベスト曝露により誘導されるストレス応答の研究2017
- Author(s)
  松﨑秀紀、李順姫、前田　恵、武井直子、吉留　敬、西村泰光、大槻剛巳
- Organizer
  第24回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15K08788
[Presentation] MT-2細胞に対する短期および長期のアスベスト曝露の影響の研究2017
- Author(s)
  松﨑秀紀，李順姫，前田恵，武井直子，西村泰光，吉留敬，大槻剛巳
- Organizer
  第87回日本衛生学会学術総会
- Place of Presentation
  フェニックス・シーガイア・リゾート（宮崎県宮崎市）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-15K08788
[Presentation] Secretory factors produced by immune cells upon exposure to asbestos facilitate proliferation of mesothelial cells2017
- Author(s)
  Nishimura Y, Kumagai-Takei N, Otsuki T
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Differential effects of IL-2 and IL-15 addition on numbers and granzyme B level in CD8+ lymphocytes exposed to asbestos during MLR.2017
- Author(s)
  Kumagai-Takei N. Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T.
- Organizer
  The 56th Annual Meeting of the Society of Toxicology
- Place of Presentation
  Baltimore Convention Center　（Maryland, USA）
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] Continuous and low-dose exposure to asbestos on human T cells causes reduction of anti-tumor immunity2017
- Author(s)
  Otsuki T, Maeda M, Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Sada N, Nishimura Y
- Organizer
  International Conference on Environmental Health and Environmental-related Cancer Prevention 2017: Assessing low-doses and cumulative effects of exposure to chemical mixtures
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] Titanate nanosheets cause caspase-dependent apoptosis of human immune cells with giant vacuole formation through endosomal defect in monochytes2017
- Author(s)
  Nishimura Y, Yoshioka D, Kumagai-Takei N, Lee S, Matsuzaki H, Yoshitome K, Otsuki T
- Organizer
  The 53rd Congress of the European Societies of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15245
[Presentation] Effect of Short-Term and Long-Term Exposure of Asbestos on Human T Cell Line MT-2.2017
- Author(s)
  Matsuzaki, H., Lee, S., Maeda, M., Kumagai-Takei, N., Yoshitome, K., Nishimura, Y., Otsuki, T.
- Organizer
  The 56th Annual Meeting of the Society of Toxicology
- Place of Presentation
  The Baltimore Convention Center (Baltimore, Maryland, USA)
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08788
[Presentation] The immunological screening devices for human malignant mesothelioma and asbestos exposure2017
- Author(s)
  Nishimura Y, Lee S, Kumagai-Takei N, Mastuzaki H, Yoshitome K, Otsuki T
- Organizer
  The 27th Japan Korea China Conference on Occupational Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] チタン酸ナノシート曝露によるヒトPBMCのアポトーシスと単球における巨大空胞形成2017
- Author(s)
  西村泰光，吉岡大輔，李順姫，武井直子，松崎秀紀，吉留敬，大槻剛巳
- Organizer
  第90回日本産業衛生学会
- Data Source
  KAKENHI-PROJECT-15K15245
[Presentation] The analysis for function of human CD8+T cell line with and without long-term exposure to asbestos fibers.2017
- Author(s)
  Kumagai-Takei N, Nishimura Y, Otsuki T.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] 免疫細胞由来因子により引き起こされるヒト中皮細胞増殖脳の石綿耐性2017
- Author(s)
  西村泰光，李順姫，武井直子，松﨑秀紀，吉留敬，大槻剛巳
- Organizer
  第87回日本衛生学会学術総会
- Place of Presentation
  フェニックス・シーガイア・リゾート, 宮崎県, 宮崎市
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] 長期石綿曝露によるヒトCD8T細胞の機能変化．2017
- Author(s)
  武井直子、西村泰光、松﨑秀紀、李順姫、吉留敬、大槻剛巳．
- Organizer
  第24回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] 悪性中脾腫患者とびまん性胸膜肥厚患者の包括的免疫機能解析2017
- Author(s)
  西村泰光、李順姫、武井直子、松﨑秀紀、岡本賢三、岸本卓巳、大槻剛巳
- Organizer
  第88回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] 長期石綿曝露がヒトCD8+T細胞亜株の機能に与える影響．2017
- Author(s)
  武井直子，西村泰光，松﨑秀紀，李順姫，吉留敬，大槻剛巳．
- Organizer
  第87回日本衛生学会学術総会
- Place of Presentation
  シーガイアコンベンションセンター（宮崎市）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] 石綿曝露によるCTL分化抑制時のIL-15添加の影響．2016
- Author(s)
  武井直子，西村泰光，松﨑秀紀，李順姫，吉留敬，大槻剛巳．
- Organizer
  第86回日本衛生学会学術総会
- Place of Presentation
  旭川市民文化会館（旭川市）
- Year and Date
  2016-05-11
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] The Role of Transcription Factor FoxP3 in the Asbestos-Induced Apoptosis in MT-2 Cells.2016
- Author(s)
  Matsuzaki H. Lee S, Maeda M, Kumagai-Takei N, Yoshitome K, Nishimura Y, Otsuki T.
- Organizer
  The 55th Annual Meeting of the Society of Toxicology
- Place of Presentation
  Ernest N. Morial Convention Center, New Orleans, USA
- Year and Date
  2016-03-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08788
[Presentation] Differential effects of IL-2 and IL-15 on the suppressed induction of CTL upon exposure to asbestos.2016
- Author(s)
  Kumagai-Takei N, Nishimura Y, Otsuki T.
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（那覇市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] Study for Immunological Importance of Increased Plasma Decoy Receptor 3 Level in Silicosis2016
- Author(s)
  Lee S. Nishimura Y, Yamamoto S, Hatayama T, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Hayashi H, Uragami K, Kusaka M, Fujimoto W, Otsuki T.
- Organizer
  The 55th Annual Meeting of the Society of Toxicology
- Place of Presentation
  New Orleans, Louisiana, U.S.A．
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] Vacuole Formation And Caspase-dependent Apoptosis In Human Monocytes Caused By Exposure To Titanate Nanosheet2016
- Author(s)
  Nishimura Y, Yoshioka D, Lee S, Kumagai-Takei N, Matsuzaki H, Yoshitome K, Otsuki T
- Organizer
  The 55th Annual Meeting. Society of Toxicology
- Place of Presentation
  New Orleans Ernest N． Morial Convention Center (New Orleans, Louisiana)
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15245
[Presentation] アスベスト曝露と悪性中皮腫に関わる免疫学的特徴の解析とスクリーニングデバイスの開発2016
- Author(s)
  西村泰光，李順姫，武井直子，松﨑秀紀，吉留敬，大槻剛巳
- Organizer
  第23回日本免疫毒性学会学術年会
- Place of Presentation
  北九州国際会議場, 福岡県, 北九州市
- Year and Date
  2016-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] 悪性中皮腫スクリーニングデバイスとしての免疫学的スコア式の開発2016
- Author(s)
  西村泰光，李順姫，武井直子，吉留敬，岸本卓巳，福岡和也，田端千春，中野孝司，大槻剛巳
- Organizer
  第89回日本産業衛生学会
- Place of Presentation
  福島県文化センター, 福島県, 福島市
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-16H05264
[Presentation] MT-2 細胞を用いた短期および長期のアスベスト曝露の影響の解析2016
- Author(s)
  松﨑秀紀，李順姫，前田恵，武井直子，西村泰光，大槻剛巳
- Organizer
  第23回日本免疫毒性学会学術年会
- Place of Presentation
  北九州国際会議場（福岡県北九州市)
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PROJECT-15K08788
[Presentation] 空砲形成を伴う細胞死を惹起するチタン酸ナノシートの単球への取り込みと細胞内動態2016
- Author(s)
  西村泰光, 吉岡大輔, 李順姫, 武井直子, 松崎秀紀, 吉留敬, 大槻剛巳
- Organizer
  第86回日本衛生学会学術総会
- Place of Presentation
  旭川市民文化会館, 北海道, 旭川市
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K15245
[Presentation] 石綿曝露下 CTL 分化抑制時の CD8+T 細胞に及ぼす IL-15 添加の影響．2016
- Author(s)
  武井直子，西村泰光，松﨑秀紀，李順姫，吉留敬，大槻剛巳．
- Organizer
  第23回日本免疫毒性学会学術年会
- Place of Presentation
  北九州国際会議場（北九州市）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PROJECT-16K09114
[Presentation] The characteristic cell death of human monocytes caused by exposure to nano-sized and sheet-like titanate2015
- Author(s)
  西村泰光, 武井直子, 松崎秀紀, 李順姫, 大槻剛巳
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K15245
[Presentation] チタン酸ナノシート曝露による単球の空胞形成と細胞死2015
- Author(s)
  西村泰光, 吉岡大輔, 李順姫, 武井直子, 松崎秀紀, 吉留敬, 大槻剛巳
- Organizer
  第22回日本免疫毒性学会学術年会
- Place of Presentation
  京都大学百周年時計台記念館国際交流ホール（京都）
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15K15245
[Presentation] 自己免疫疾患未発症珪肺症例における血漿免疫グロブリンとBAFF値の解析2015
- Author(s)
  李順姫，西村泰光，山本祥子，幡山圭代，松崎秀紀，武井直子，吉留敬，大槻剛巳．
- Organizer
  第22回日本免疫毒性学会学術年会
- Place of Presentation
  京都大学百周年時計台記念館国際交流ホール（京都）
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] FoxP3 に対するアスベスト長期曝露影響の解析2015
- Author(s)
  松﨑秀紀，李順姫，前田恵，武井直子，西村泰光，大槻剛巳
- Organizer
  第22回日本免疫毒性学会学術年会
- Place of Presentation
  京都大学（京都）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K08788
[Presentation] 珪肺症における血清DcR3分子の病態における位置付け2015
- Author(s)
  李順姫，大槻剛巳，松崎秀紀，武井直子，吉留敬，西村泰光，草加勝康，浦上更三
- Organizer
  第59回中国四国合同産業衛生学会
- Place of Presentation
  愛媛大学城北キャンパス南加記念ホール（松山）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] Analysis between blood DcR3 level, autoantibodies and respiratory score in silicosis patients.2015
- Author(s)
  Lee S, Nishimura Y, Yamamoto S, Hatayama T, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Otsuki T.
- Organizer
  31st ICOH (International Congress on Occupational Health)
- Place of Presentation
  COEX Convention Center, Seoul, Korea
- Year and Date
  2015-05-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] 珪肺症における免疫異常：血漿 Decoy Receptor 3 の位置付け診断指標の構築2015
- Author(s)
  大槻剛巳，李順姫，武井直子，松崎秀紀，吉留敬，西村泰光，林宏明，浦上更三，草加勝康，藤本亘
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  ANAクラウンプラザホテル金沢など（金沢）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] Role of FoxO1 and FoxP3 in Asbestos-induced Apoptosis of MT-2 Cells.2015
- Author(s)
  Matsuzaki H, Lee S, Maeda M, Kumagai-Takei N, Nishimura Y, Otsuki T.
- Organizer
  31st International Congress on Occupational Health
- Place of Presentation
  COEX Convention Center, Seoul, Korea
- Year and Date
  2015-06-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08788
[Presentation] Differences of immunological effects of crystalline silica and asbestos fibers on regulatory T cell2015
- Author(s)
  Lee S, Otsuki T.
- Organizer
  The 54th Annual Meeting of the Society of Toxicology
- Place of Presentation
  San Diego Convention Center in San Diego, California, 米国
- Year and Date
  2015-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] 珪肺症例における血漿DcR3値と各種自己免疫疾患関連因子との相関性の検討2014
- Author(s)
  李順姫，西村泰光，山本祥子，幡山圭代，松崎秀紀，武井直子，大槻剛巳.
- Organizer
  第13回分子予防環境医学研究会
- Place of Presentation
  和歌山県民文化会館　大会議室
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] Analysis of blood DcR3 concentration andits correlation to clinical paramaters of autoimmune diseases in silicosis patients.2014
- Author(s)
  Lee S, Nishimra Y, Yamamoto S, Hatayama T, Mastuzaki H, Kumagai-Takei N, Hayashi H, Kusaka M, Fujimoto W, Otsuki T.
- Organizer
  The 53rd annual Meeting. Society of Toxicology
- Place of Presentation
  Phoenix, AZ, USA
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] 悪性中皮腫患者および胸膜プラーク陽性者の末梢血における免疫学的特徴2014
- Author(s)
  西村泰光, 李順姫, 武井直子, 松﨑秀紀, 岸本卓巳, 福岡和也,田端千春, 中野孝司, 大槻剛巳
- Organizer
  第5回JMIG (Japan Mesothelioma Interest Group)研究会
- Place of Presentation
  京都（京都私学会館）
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 悪性中皮腫および全身性強皮症患者における免疫関連遺伝子発現動態の解析2013
- Author(s)
  西村泰光，李順姫，武井直子，松﨑秀紀，林宏明，藤本亘，守田吉孝，岸本卓巳，大槻剛巳
- Organizer
  第83回日本衛生学会
- Place of Presentation
  金沢大学（金沢）
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] Continuous exposure of asbestos on Treg model cell line MT-2 affects cellcycle progression and cell surbvival.2013
- Author(s)
  Lee S, Matsuzaki H, Maeda M, Kumagai-Takei N, Nishimura , Otsuki T.
- Organizer
  2013日本免疫学会・学術集会
- Place of Presentation
  千葉、幕張メッセ
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] Long-term exposure of asbestos affects cell cycle and cell death in Treg model cell line MT-2.2013
- Author(s)
  Lee S, Matsuzaki H, Maeda M, Kumagai-Takei N, Nishimura Y, Otsuki T.
- Organizer
  6th International Symposium on Nanotechnology, Occupational and Environmental Health.
- Place of Presentation
  Nagoya Congress Center
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] Effects of asbestos exposure on regulatory role of NK cells for expanded autologous CD4+ T cells2013
- Author(s)
  Nishimura Y, Kumagai-Takei N, Matsuzaki H, Lee S, Otsuki T
- Organizer
  The 52nd Annual Meeting, Society of Toxicology
- Place of Presentation
  Henry B. Gonzalez Convention Center (San Antonio, Texas)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 石綿長期曝露制御性T細胞株における細胞周期制御因子の発現動態の解析2013
- Author(s)
  李順姫，松﨑秀紀，武井直子，西村泰光，大槻剛巳．
- Organizer
  第20回石綿・中皮腫研究会
- Place of Presentation
  東京、(公財)がん研究会がん研究所　吉田講堂
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] Carbon nanotubes-indued decrease in cytotoxicity of NK cells with altered expression of NK cell-activating receptors2012
- Author(s)
  Nishimura Y, Kumagai-Takei N, Matsuzaki H, Lee S, Maeda M, Otsuki T
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場・神戸国際展示場（神戸）
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 末梢血中の多項目サイトカイン濃度測定に基づく悪性中皮腫診断指標構築2012
- Author(s)
  西村泰光，武井直子，松﨑秀紀，李順姫，大槻剛巳
- Organizer
  第85回日本産業衛生学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 免疫学的所見に基づくアスベスト曝露者の病態解析と診断指標構築の試み＜シンポジウム「免疫毒性学研究の進歩」＞2012
- Author(s)
  西村泰光，武井直子，松﨑秀紀，李順姫，前田恵，岸本卓巳，大槻剛巳
- Organizer
  第19回日本免疫毒性学会
- Place of Presentation
  東京慈恵会医科大学（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] アスベスト低濃度長期曝露制御性T細胞株でのFoxP3遺伝子メチル化の変化2011
- Author(s)
  大槻剛巳, 他
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  震災による中止も誌上発表:日本衛生学会誌6682), 503, 2011
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] マイナス荷電粒子優位な室内環境の免疫影響2011
- Author(s)
  大槻剛巳, 高橋一聡, 真鍋弘穀, 小谷宗男, 前田恵, 熊谷直子, 松崎秀紀, 李順姫, 西村泰光
- Organizer
  第18回日本免疫毒性学会
- Place of Presentation
  千葉大学けやき会館(千葉県)
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] 室内空気質による健康増進への取組に関する基礎的研究2011
- Author(s)
  大槻剛巳
- Organizer
  第2回川崎医科大学学術集会
- Place of Presentation
  川崎医科大学現代医学教育博物館(岡山県)
- Year and Date
  2011-08-06
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] Effect of asbestos exposure on production of cytokines, apoptosis, and cell prolifertion related with differentiation of human CTL.2011
- Author(s)
  Kumagai N, Nishimura Y, Maeda M, Hayashi H, Otsuki T
- Organizer
  The 50th Anniversary Annual Meating of Society of Toxicology (U.S.A.).
- Place of Presentation
  Walter E. Washington Convention Center, Washington D.C. U.S.A.
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 健康増進住宅への試み2011
- Author(s)
  大槻剛巳
- Organizer
  第39回メディカルテクノおかやまサロン
- Place of Presentation
  岡山大学鹿田キャンパス総合教育研究棟1階
- Year and Date
  2011-04-25
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] 室内空気質による健康増進への取組に関する基礎的研究2011
- Author(s)
  大槻剛巳
- Organizer
  第2回川崎医科大学学術集会
- Place of Presentation
  川崎医科大学現代医学教育博物館
- Year and Date
  2011-08-06
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] Continuous and low-dose exposure to asbestos enhances TGF-β1 production in a human adult T cell leukemia virus-immortalized T cell line, MT-2.2011
- Author(s)
  Otsuki T, Maeda M, Kumagai N, Miyahara N, Katoh M, Yamamoto S, hatayama T, Nishimura Y
- Organizer
  The 50th Anniversary Annual Meating of Society of Toxicology (U.S.A.).
- Place of Presentation
  Walter E. Washington Convention Center, Washington D.C. U.S.A.
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 症例登録制度,基礎研究(細胞株を用いた中皮腫細胞特性およびアスベストの免疫影響.シンポジウム2(繊維・粒子状物質研究会)科学技術振興調整費「アスベスト関連疾患への総括的取り組み」班研究の成果と総括2011
- Author(s)
  大槻剛巳, 他
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  震災による中止も誌上発表:日本衛生学会誌6682), 273, 2011
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Continuous and low-dose exposure to asbestos enhances TGF-β1 production in a human adult T cell leukemia virus-immortalized T cell line, MT-2.2011
- Author(s)
  Otsuki T, 他
- Organizer
  The 50th Anniversary Annual Meating of Society of Toxicology (U.S.A).
- Place of Presentation
  Walter E.Washington Convention Center, Washington D.C. U.S.A
- Year and Date
  2011-03-07
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] アスベストによる免疫防御機構の破綻の解明.シンポジウム「環境発癌から分子標的予防まで」2011
- Author(s)
  大槻剛巳
- Organizer
  第10回分子予防環境医学研究会大会
- Place of Presentation
  京都府立医科大学医学部旧図書館棟3階講堂
- Year and Date
  2011-01-21
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Asbestos exposure causes decrease in production of cytokines related to Nk cell activation.2011
- Author(s)
  Nishimura Y, Kumagai N, Maeda M, Hayashi H, Otsuki T
- Organizer
  The 50th Anniversary Annual Meating of Society of Toxicology (U.S.A.).
- Place of Presentation
  Walter E. Washington Convention Center, Washington D.C. U.S.A.
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Enhanced suppressive function on regulatory T cell-like cell line, MT-2, by continuous exposure to asbestos.2011
- Author(s)
  Maeda M, Chen Y, Nishimura Y, Kumagai N, Hayashi H, Miura Y, Otsuki T
- Organizer
  The 50th Anniversary Annual Meating of Society of Toxicology (U.S.A.).
- Place of Presentation
  Walter E. Washington Convention Center, Washington D.C. U.S.A.
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] REduced alteration of the regulatory function of CD4+25+ T cell fraction in silicosis patients.2010
- Author(s)
  Hayashi H, Maeda M, Nishimura Y, Kumagai N, Miura Y, Otsuki T.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe International Exhibition Hall
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Suppressive effect of asbestos on cytotoxicity of human NK cells.2010
- Author(s)
  Nishimura Y, Kumagai N, Maeda M, Hayashi H, Fukuoka K, Nakano T, Kishimoto T, Otsuki T
- Organizer
  ISOEAID'10 in KYOTO (International symposium on Occupational and Environmental Allergy and Immune Diseases 2010 in KYOTO (Local Organizer: Otsuki T)
- Place of Presentation
  KYODAI-KAIKAN (Kyoto, Japan)
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Alteration of cellular characteristics of HTLV-1 immortalized human T cell line, MT-2, by continuous long-term exposre to asbestos, chrysotile and crocidolite.2010
- Author(s)
  Otsuki T, Miura Y, Maeda M, Kumagai N, Hayahsi H, Nishimura Y
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe International Exhibition Hall
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 珪肺症例の制御性T細胞のCD95媒介アポトーシスに対する高感受性2010
- Author(s)
  大槻剛巳, 他
- Organizer
  第41回日本職業・環境アレルギー学会総会・学術大会/第57回日本産業衛生学会アレルギー・免疫毒性研究会合同大会
- Place of Presentation
  高崎ビューホテル
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Decreased cytotoxity of human NK cells with low expression of NK cell-activating receptors upon exposure to asbestos, related with malignant mesotheioma.2010
- Author(s)
  Nishimura Y, Kumagai N, Maeda M, Hayashi H, fukuoka K, Nakano T, Kishimoto T, Otsuki T
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe International Exhibition Hall
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Suppressive effects of asbestos-exposure on the differentiation of human cytotoxic T lymphocytes, accompanied with decrease in IFN-γ and TNF-α.2010
- Author(s)
  Kumagai N, Nishimura Y, Maeda M, Hayashi H, Kishimoto T, Otsuki T
- Organizer
  The 10th International Congress of the iMiG (International Mesotheloma Interest Group)
- Place of Presentation
  Kyoto International Conference Center
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 科学技術振興調整費「アスベスト関連疾患への総括的取り組み」班悪中皮腫集学的治療に関する安全性確認試験ならびに基礎研究の進捗状況2010
- Author(s)
  大槻剛巳, 他
- Organizer
  第58回日本職業・災害医学会
- Place of Presentation
  サンルートプラザ東京(舞浜)
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] functional analysis of human CD4+ T cells with decreased CXCR3 expression by long-term, low-dose exposure to asbestos.2010
- Author(s)
  Maeda M, Nishimura Y, Kumagai N, Hayashi H, Miura Y, Kishimoto T, Otsuki T
- Organizer
  The Society of Toxicology (SOT) The 49th Annual Meeting in Salt Lake City, Utah
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] The effects of cntinuous long-term exposure to asbestos, chrysotile and crocidolite on HTLV=1 immortalized human T cell line, MT-2.2010
- Author(s)
  Otsuki T, Maeda M, Miura Y, Kumagai N, Hayashi H, Yamamoto S, Nishimura Y
- Organizer
  The 10th International Congress of the iMiG (International Mesotheloma Interest Group)
- Place of Presentation
  Kyoto International Conference Center
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Immunological effects of silica and asbestos.2010
- Author(s)
  Otsuki T, et al
- Organizer
  ISOEAID'10 in KYOTO (International symposium on Occupational and Environmental Allergy and Immune Diseases 2010 in KYOTO
- Place of Presentation
  KYODAI-KAIKAN (Kyoto, Japan)
- Year and Date
  2010-04-08
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 住居環境と健康2010
- Author(s)
  大槻剛巳
- Organizer
  おかやま生体信号研究会第3回例会.
- Place of Presentation
  川崎医療福祉大学講義棟4603講義室
- Year and Date
  2010-05-31
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] クリソタイル低濃度長期曝露ヒトT細胞株における制御性T細胞機能の解析2010
- Author(s)
  大槻剛巳, 他
- Organizer
  第83回日本産業衛生学会
- Place of Presentation
  フェニックスプラザ(福井市),福井県国際交流会館
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] アスベスト曝露による腫瘍免疫減衰と,その回復2010
- Author(s)
  大槻剛巳
- Organizer
  バイオアカデミックフォーラム/バイオテクノロジー国際会議/国際バイオエキスポ
- Place of Presentation
  東京ビッグサイト
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] アスベスト曝露MT-2細胞におけるT細胞増殖抑制機能亢進とDNAメチル化変化2010
- Author(s)
  大槻剛巳, 他
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] suppressive effects of asbestos-exposure on the differentiation into human cytotoxic T lymphocytes2010
- Author(s)
  Kumagai N, Nishimura Y, Maeda M, Hayashi H, Otsuki T
- Organizer
  The Society of Toxicology (SOT) The 49th Annual Meeting in Salt Lake City, Utah
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Differentiation into human cytotoxic T lymphocytes are suppressed under exposure to asbestos.2010
- Author(s)
  Kumagai N, Nishimura Y, Maeda M, Hayashi H, Otsuki T
- Organizer
  ISOEAID'10 in KYOTO (International symposium on Occupational and Environmental Allergy and Immune Diseases 2010 in KYOTO (Local Organizer: Otsuki T)
- Place of Presentation
  KYODAI-KAIKAN (Kyoto, Japan)
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Human MT-2 cell line displays enhanced suppressive function by chronic exposure to asbestos.2010
- Author(s)
  Maeda M, Nishimura Y, Kumagai N, Hayashi H, Miura Y, Otsuki T
- Organizer
  The 10th International Congress of the iMiG (International Mesotheloma Interest Group)
- Place of Presentation
  Kyoto International Conference Center
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Immunological effects of silica and asbestos.2010
- Author(s)
  Otsuki T, Maeda M, Miura Y, Hayashi H, Kumagai N, Fukuoka K, Nakano T, Kishimoto T, Kusaka M, Uragami K, Nishimura Y.
- Organizer
  ISOEAID'10 in KYOTO (International symposium on Occupational and Environmental Allergy and Immune Diseases 2010 in KYOTO (Local Organizer: Otsuki T)
- Place of Presentation
  KYODAI-KAIKAN (Kyoto, Japan)
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] アスベストの免疫影響:クリソタイルとクロシドライトの低濃度長期曝露によるヒトT細胞株への影響の相違2010
- Author(s)
  大槻剛巳, 他
- Organizer
  第51回日本肺癌学会
- Place of Presentation
  広島国際会議場・ANAクラウンプラザホテル広島
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 珪肺症例における免疫異常:症例および末梢血CD4+25+分画の機能2010
- Author(s)
  大槻剛巳, 他
- Organizer
  第54回中国四国合同日本産業衛生学会
- Place of Presentation
  海峡メッセ下関
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Effects of asbestos on T-lymphocytes and NK cells in the development of tumor immunity2010
- Author(s)
  Otsuki T, et al
- Organizer
  The Society of Toxicology(SOT)Annual Meeting
- Place of Presentation
  Salt Lake City, Utah
- Year and Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Decreased induction of human CTL upon exposure to asbestos fibers2010
- Author(s)
  Kumagai N, Nishimura Y, Maeda M, Hayashi H, Otsuki T.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe International Exhibition Hall
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Asbestos-exposure causes suppressed expression of NKp46 with low cytotoxicity in NK cells, related with malignant mesothelioma.2010
- Author(s)
  Nishimura Y, Kumagai N, Maeda M, Hayashi H, Kishimoto Y, Otsuki T
- Organizer
  The Society of Toxicology (SOT) The 49th Annual Meeting in Salt Lake City, Utah
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Relevance of chemokine receptor CXCR3 in asbestos-related diseases.2010
- Author(s)
  Maeda M, Nishimura Y, Kumagai N, Hayashi H, Miura Y, Kishimoto T, Otsuki T
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe International Exhibition Hall
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Soluble interleukin-2 receptor as a marker of immunological disturbance found in silicosis patients.2010
- Author(s)
  Otsuki T, et al
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Application of CXCR3 expression in CD4+ T cells to the diagnosis of asbestos-related diseases.2010
- Author(s)
  Maeda M, Nishimura Y, Kumagai N, Hayashi H, Miura Y, Kishimoto T, Otsuki T
- Organizer
  The 21st Japan China Korea Joint Conference on Occupational Health.
- Place of Presentation
  Tochigi-ken Sogo Bunka Center, Utsunomiya, JAPAN
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 基礎研究の進展と登録制度.科学技術振興調整費中皮腫研究班特別報告2010
- Author(s)
  大槻剛巳
- Organizer
  第51回日本肺癌学会
- Place of Presentation
  広島国際会議場・ANAクラウンプラザホテル広島
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] アスベスト繊維(クリソタイルとクロシドライト)による免疫影響の比較2010
- Author(s)
  大槻剛巳, 他
- Organizer
  第17回日本免疫毒性学会学術大会
- Place of Presentation
  独立行政法人国立環境研究所大山記念ホール
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Analysis of immune index in asbesots-related disease.2010
- Author(s)
  Maeda M, Nishimura Y, Kumagai N< Hayashi H, Miura Y, Kishimoto T, Otsuki T
- Organizer
  ISOEAID'10 in KYOTO (International symposium on Occupational and Environmental Allergy and Immune Diseases 2010 in KYOTO (Local Organizer: Otsuki T)
- Place of Presentation
  KYODAI-KAIKAN (Kyoto, Japan)
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Exposure to Asbestos Suppressed the Differentiation of Human Cytotoxic T Lymphocytes.2010
- Author(s)
  Kumagai N, Nishimura Y, Maeda M, Hayashi H, Otsuki T
- Organizer
  The 21st Japan China Korea Joint Conference on Occupational Health.
- Place of Presentation
  Tochigi-ken Sogo Bunka Center, Utsunomiya, JAPAN
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Decrease in NKp46 in NK cells upon exposure to asbestos, a possible marker tomonitor anti-tumor immunity.2010
- Author(s)
  Nishimura Y, Kumagai N, Maeda M, Hayashi H, Kishimoto T, Otsuki T
- Organizer
  The 10th International Congress of the iMiG (International Mesotheloma Interest Group)
- Place of Presentation
  Kyoto International Conference Center
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Decreased Cytotoxicity of NK Cells with Low NKp46 Caused by Exposure to Asbestos, Observed in Patients with Mesothelioma.2010
- Author(s)
  Nishimura Y, Kumagai N, Maeda M, Hayashi H, Kishimoto T, Otsuki T
- Organizer
  The 21st Japan China Korea Joint Conference on Occupational Health.
- Place of Presentation
  Tochigi-ken Sogo Bunka Center, Utsunomiya, JAPAN
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 珪肺症におけるsIL-2R・sCD40L測定と免疫異常との関連2010
- Author(s)
  大槻剛巳, 他
- Organizer
  第19回日本臨床環境医学会学術集会
- Place of Presentation
  北里大学白金キャンパス
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Effects of asbestos on T-lymphocytes and NK cells in the development of tumor immunity.2010
- Author(s)
  Otsuki T, Maeda M, Kumagai N, Hayashi H, Nishimura Y
- Organizer
  The Society of Toxicology (SOT) The 49th Annual Meeting in Salt Lake City, Utah
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] マイナス荷電粒子優位の室内空気環境と精神・神経・内分泌・免疫ネットワーク応答の解析-in vitro実験系の試み-2010
- Author(s)
  大槻剛巳, 西村泰光, 前田恵, 熊谷直子, 林宏明
- Organizer
  第1回川崎医科大学学術集会
- Place of Presentation
  川崎医科大学校舎棟M702/教職員ラウンジ
- Year and Date
  2010-08-07
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] 珪酸やアスベスト曝露疾患におけるサイトカインの変化と想定される免疫異常/Cytokine alteration and speculated immunological pathology in silicosis and asbestos-related diseases2009
- Author(s)
  Otsuki T, et al
- Organizer
  第16回日本免疫毒性学会学術大会
- Place of Presentation
  旭川市民文化会館
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Immunotoxicological effects of asbestos on human T cells.2009
- Author(s)
  Otsuki T, Maeda M, Murakami S, Miura Y, Kumagai N, Chen Y, Hayashi H, Nakano T, Fukuoka K, Kishimoto T, Nishimura Y
- Organizer
  The 48th Society of Toxicology (USA)
- Place of Presentation
  Baltimore Convention Center in Baltimore, Maryland
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] 環境と生体反応:健康被害から健康増進へ2009
- Author(s)
  大槻剛巳
- Organizer
  岡山県医用工学研究会平成21年度第1回セミナー
- Place of Presentation
  岡山大学鹿田キャンパス附属図書館3階情報実習室
- Year and Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] アスベストの免疫影響. 奈良県立医科大学2009
- Author(s)
  大槻剛巳
- Organizer
  住居医学研究会
- Place of Presentation
  奈良県立医科大学基礎医学校舎5階会議室
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] effects of environmental substances on human immunocompetent cells : An asbestos2009
- Author(s)
  Otsuki T, et al
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都国際会館
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] マイナス荷電空気環境による効果2009
- Author(s)
  大槻剛巳, 他
- Organizer
  第79回日本衛生学会総会.「森林の健康影響メカニズムをさぐる」森林医学研究会
- Place of Presentation
  北里大学白金キャンパス
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] Suppressive effect of asbestos-exposure on cytotoxicity of human NK cells, and the possibility of NKp46 as a marker to monitor immune status in people exposed to asbestos.2009
- Author(s)
  Nishimura Y, Maeda M, Kumagai N, Murakami S, Hayashi H, Kishimoto T, Fukuoka K, Nakano T, Otsuki T
- Organizer
  第2回日中石綿シンポジウム, New CEntury Zhijiang Resort Hangzhou
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] アスベスト曝露による免疫監視機構の障害.シンポジウム「アスベスト関連疾患・病態から治療まで」2009
- Author(s)
  大槻剛巳
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  国際会館(京都)
- Year and Date
  2009-05-01
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] マイナス荷電空気環境による効果2009
- Author(s)
  大槻剛巳, 西村泰光, 森本兼曩
- Organizer
  第79回日本衛生学会総会「森林の健康影響メカニズムをさぐる」森林医学研究会
- Place of Presentation
  北里大学白金キャンパス
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-21659161
[Presentation] 環境と生体反応:健康被害から健康増進へ2009
- Author(s)
  大槻剛巳
- Organizer
  岡山県医用工学研究会平成21年度第1回セミナー
- Place of Presentation
  岡山大学鹿田キャンパス附属図書館3階情報実習室
- Year and Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] アスベスト低濃度継続曝露T細胞株における制御性T細胞機能の増強2009
- Author(s)
  大槻剛巳, 他
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Keynote Speach (3). Achivement of Research Project "Comprehensive approach on asbestos-related diseases (sponsered by SCFPST)" and immunological effects of asbestos2008
- Author(s)
  Takemi Otsuki.
- Organizer
  AAI (Asian Asebestos Initiative) International Conference in Kitakyushu
- Place of Presentation
  産業医大
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Immunological changes in mesothelioma patients and their experimental detection.2008
- Author(s)
  Otsuki T,Maeda M, Murakami S,Hayashi H, Kumagai N,Miura Y,Ying C,Kuribayashi K,Fukuoka K,Kishimoto T,Nakano T,Nishimura Y
- Organizer
  Inetrnational Mesothelioma Interest Group. Congress 2008
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Keynote Speach (3). Achivement of Research Project "Comprehensive approach on asbestos-related diseases (sponsered by SCFPST)" and immunological effects of asbestos2008
- Author(s)
  Takemi Otsuki.
- Organizer
  AAI (Asian Asebestos Initiative) International Conference in Kitakyushu
- Place of Presentation
  産業医大
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-19659153
[Presentation] Impairment in cytotoxicity and expression of NK-cell activating receptors on human NK cells caused by exposure to asbestos fibers.2008
- Author(s)
  Nishimura Y, Maeda M, Murakami S, Hayashi H, Miura Y, fukuoka K, Nakano T, Otsuki T
- Organizer
  Inetrnational Mesothelioma Interest Group. Congress 2008
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Down-regulation of chemokine receptor CXCR3 in peripheral T lymphocytes from patients with asbestos-related disease.2008
- Author(s)
  Maeda M, Nishimura Y, Murakami S, Kumagai N, Hayashi H, Ying C, Miura Y, Nakano T, Kishimoto T, Otsuki T
- Organizer
  Inetrnational Mesothelioma Interest Group. Congress 2008
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Keynote Speach (3). Achivement of Research Project "Comprehensive approach on asbestos-related diseases (sponsered by SCFPST)" and immunological effects of asbestos.2008
- Author(s)
  Otsuki T.
- Organizer
  AAI (Asian Asebestos Initiative) International Conference in Kitakyushu
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-20390178
[Presentation] Immunological effects of asbestos2007
- Author(s)
  Otsuki T, Maeda M, Miura Y, Murakami S, Hayashi H, Nishimura Y, Ikuribayashi K, Fukuoka K, Nakano T.
- Organizer
  66th Annual Meeting of the Japanese Cancer Aseociation(English Session)
- Place of Presentation
  Pacifica Yokohama,Yokohama,Kanagawa,Japan
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18390186
[Presentation] Immunological effects of asbestos2007
- Author(s)
  Otsuki T, Maeda M, Miura Y, Murakami S, Hayashi H, Nishimura Y, Kuribayashi K, Fukuoka K, Nakano T.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association (English Session)
- Place of Presentation
  Pacifica Yokohama,Yokohama,Kanagawa,Japan
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390186
[Presentation] Immunological effects of asbestos2007
- Author(s)
  Otsuki T, Maeda M, Miura Y, Murakami S, Hayashi H, Nishimura Y, Kuribayashi K, Fukuoka K, Nakano T.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association(English Session)
- Place of Presentation
  Pacifica Yokohama,Yokohama,Kanagawa,Japan
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19659153
[Presentation] チタン酸ナノシートの末梢血単核球に対する毒性影響
- Author(s)
  西村泰光，吉岡大輔，李順姫，武井直子，松﨑秀紀，大槻剛巳
- Organizer
  第20回日本免疫毒性学会学術年会
- Place of Presentation
  東海大学代々木キャンパス (東京)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] Immunological similarity and difference between individuals positive for pleural plaque with malignant mesothelioma, rebealed by analysis for mRNA levels
- Author(s)
  Nishimura Y, Lee S Kumagai-Takei N, Matsuzaki H, Otsuki T
- Organizer
  The 43rd Annual Meeting of The Japanese Society for Immunology
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 珪肺症と強皮症における免疫機能亢進の類似およびTh細胞機能の差違
- Author(s)
  西村泰光，李順姫, 武井直子, 松﨑秀紀, 藤本亘, 林宏明 , 守田吉孝 , 大槻剛巳
- Organizer
  第13回分子予防環境医学研究会
- Place of Presentation
  和歌山県民文化会館 (和歌山)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] カーボンナノチューブ曝露によるNK細胞機能低下
- Author(s)
  西村泰光，武井直子，松﨑秀紀，李順姫，平野靖史郎，大槻剛巳
- Organizer
  第19回石綿・中皮腫研究会
- Place of Presentation
  ホテル北野プラザ（神戸）
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] Suppressive effects of exposure to multi-walled carbon nanotubes and asbestos on NK cell function
- Author(s)
  Nishimura Y, Kumagai-Takei N, Mastuzaki H, Lee S, Otsuki T
- Organizer
  6th International Symposium on Nanotechnology, Occupational and Environmental Health
- Place of Presentation
  名古屋国際会議場 (名古屋)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] Analysis of blood DcR3 concentration and its correlation to autoantibodies in silicosis patients.
- Author(s)
  Lee S, Nishimura Y, Yamamoto S, Hatayama T, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Otsuki T.
- Organizer
  The 21st The Asian Association for Occupational Health
- Place of Presentation
  Hilton Fukuoka Sea Halk、福岡
- Year and Date
  2014-09-02 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] 多面的免疫機能解析による珪肺と全身性強皮症の比較
- Author(s)
  西村泰光，李順姫，武井直子，松崎秀紀，林宏明，藤本亘，守田吉孝，草加勝康，大槻剛巳
- Organizer
  第87回日本産業衛生学会
- Place of Presentation
  岡山（岡山コンベンションセンター）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 珪酸・アスベストの免疫影響
- Author(s)
  西村泰光，武井直子，李順姫，松崎秀紀，大槻剛巳
- Organizer
  第13回肺分子病態研究会
- Place of Presentation
  ホテルレオパレス博多 (福岡)
- Invited
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 石綿の低濃度長期曝露がTreg様モデル細胞株 MT-2細胞の細胞増殖に及ぼす影響
- Author(s)
  李順姫，松崎秀紀，前田恵，武井直子，西村泰光，大槻剛巳.
- Organizer
  第87回日本産業衛生学会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] 自己免疫疾患未発症珪肺症例にいおける血中DcR3値と他の自己抗体値や呼吸機能検査値との関連
- Author(s)
  李順姫，西村泰光，山本祥子，幡山圭代，松﨑秀紀，武井直子，吉留敬，大槻剛巳．
- Organizer
  第21回日本免疫毒性学会学術年会
- Place of Presentation
  徳島文理大学・国際会議場、徳島
- Year and Date
  2014-09-11 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] Functional Characteristics of Immune Cells in Peripheral Blood of Individuals with Pleural Plaque and Patients with Malignant Mesothelioma
- Author(s)
  Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Yoshitome K, Otsuki T
- Organizer
  The 54th Annual Meeting of the Society of Toxicology
- Place of Presentation
  San Diego, (San Diego Convention Center)
- Year and Date
  2015-03-22 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 珪肺症例における血漿中DcR3値と各種自己免疫疾患関連因子との相関性の検討
- Author(s)
  李順姫，西村泰光，松崎秀紀，武井直子，山本祥子，幡山圭代，大槻剛巳.
- Organizer
  第84回日本衛生学会学術総会
- Place of Presentation
  岡山コンベンションセンター、岡山
- Year and Date
  2014-05-25 – 2014-05-27
- Data Source
  KAKENHI-PROJECT-25460825
[Presentation] The characteristics of activated lymphocytes in silicosis differing in Th17 phenotype from systemic sclerosis
- Author(s)
  Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Hayashi H, Fujimoto W, Morita Y, Kusaka M, Otsuki T
- Organizer
  The 53rd annual Meeting. Society of Toxicology
- Place of Presentation
  Poenix Convention Center (Phoenix, Arizona)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] Immunological analysis for patients with silicosis or systemic scleroderma
- Author(s)
  Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Otsuki T
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ (千葉)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] Immunological similarity and difference observed in analyses for mRNAs, cell surface molecules and plasma cytokines between silicosis and systemic scleroderma
- Author(s)
  Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Yoshitome K, Otsuki T
- Organizer
  The 21st Asian Conference on Occupational Health
- Place of Presentation
  福岡（ヒルトン福岡シーホーク）
- Year and Date
  2014-09-02 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 珪酸が黒関連疾患における免疫動態の包括的解析．（日本毒性学会・日本免疫毒性学会合同シンポジウム「次世代が切り拓く革新的免疫毒性研究」）
- Author(s)
  西村泰光，李順姫，武井直子，松崎秀紀，大槻剛巳
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸（神戸コンベンションセンター）
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 胸膜プラーク陽性者の血漿および末梢血単核球における免疫学的特徴
- Author(s)
  西村泰光，李順姫，武井直子，松﨑秀紀，前田恵, 岸本卓巳, 福岡和也, 中野孝司, 大槻剛巳
- Organizer
  第４回JMIG研究会（Japan Mesothelioma Interest Group）
- Place of Presentation
  京都私学会館 (京都)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] Immunological characteristics in asbestos and silica-caused diseases
- Author(s)
  Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Yoshitome K, Otsuki T
- Organizer
  The 7th International Congress of Asian Society of Toxicology
- Place of Presentation
  Jeju Island, Korea (International Convention Center Jeju Island )
- Year and Date
  2015-06-23 – 2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 石綿曝露者および悪性中皮腫患者における免疫動態の解析
- Author(s)
  西村泰光，李順姫，武井直子，松崎秀紀，岸本卓巳，大槻剛巳
- Organizer
  第86回日本産業衛生学会
- Place of Presentation
  ひめぎんホール (松山)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 胸膜プラーク陽性者および悪性中皮腫患者末梢血の包括的免疫機能解析
- Author(s)
  西村泰光，李順姫，武井直子，松崎秀紀，吉留敬，岸本卓巳，福岡和也，田端千春，中野考司，大槻剛巳
- Organizer
  第85回日本衛生学会学術総会
- Place of Presentation
  和歌山（和歌山県民文化会館）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590770

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2. LEE Suni (70414026)

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OTSUKI Takemi 大槻 剛巳

大槻 剛己 オオツキ タケミ

大槻 剛巳 オオツキ タケミ

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Construction of the experimental system about the immunity influence of an indoor dispositionPrincipal Investigator

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OTSUKI Takemi 大槻剛巳

大槻剛己オオツキタケミ

大槻剛巳オオツキタケミ