Sugiura Shigeki 杉浦重樹

… Alternative Names

杉浦重樹スギウラシゲキ

SUGIURA Shigeki 杉浦重樹

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Researcher Number	40179130
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 奈良県立医科大学, 医学部, 教育教授 2020: 奈良県立医科大学, 医学部, 教育教授 2018: 奈良県立医科大学, 医学部, 教育教授 2012 – 2017: 奈良県立医科大学, 医学部, 准教授 2003 – 2005: Nara Medical University, Faculty of Medicine, Associate Professor, 医学部, 助教授 … More 2003: 奈良県立医科学大学, 医学部, 助教授 2002: 奈良県立医科大学, 総合研究施設部, 助教授 2001: 奈良県立医科大学, 組換えDNA実験施設, 助教授 1995: 金沢大学, 遺伝子実験施設, 助手 1986 – 1987: 金沢大学, 遺伝子実験施設, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related / Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals / Molecular biology Except Principal Investigator Psychiatric science / Risk sciences of radiation and chemicals / 代謝生物化学 / Neuroscience in general
Keywords	Principal Investigator 修復亢進 / DNA修復 / DNA 損傷 / 修復 / モノクローナル抗体 / 抗体 / トランスレーショナルリサーチ / シクロブタン型ダイマー / サイクロプリン / 酸化的DNA損傷 … More / CPD / ﾓﾉｸﾛｰﾅﾙ抗体 / ｼｸﾛﾌﾞﾀﾝ型ﾀﾞｲﾏｰ / シクロブタン型二量体 / leucine zipper / GroE / Rep protein / DNA replication / pSC101 / plasmid … More Except Principal Investigator radiation / repair / DNA damage / 紫外線 / 放射線 / DDB1 / 修復 / DNA損傷 / 損傷除去修復薬 / シクロブタン型二量体 / 損傷修復試薬 / 修復亢進 / CPD特異抗体 / シクロブタン型二量体(CPD) / DNA修復 / DNA binding protein / Replication origin / DNA replication / pSC101 / Plasmid / DNA複製開始 / 遺伝子発現 / DNA結合性蛋白質 / 複製開始領域 / DNA複製 / psc101 / プラスミド / astrocyte / DSB / neuron / gamma H2AX / double strand break / アストロサイト / 二本鎖切断 / 神経細胞 / γ-H2AX / UV / fluorescent protein / chaperon / oxidative stress / シャペロン / 蛍光蛋白 / シャペロ / 酸化的ストレス / Synaptic transmission / Hippocampus CA1 / Synaptic depression / Synaptic plasticity / Calcium channel / Calcium release / てんかん / 痴呆症 / 脳血管性痴呆 / 膜興奮性 / カルシウムイオン / IP3受容体 / カルシュムチャネル / カリウムチャネル / 大脳皮質 / カルシウム放出 / 細胞内カルシウム / 海馬CAI / シナプ可塑性 / カルシウムチャネル / シナプス伝達 / 海馬CA1 / シナプス抑圧 / シナプス可塑性 / カルシウムチャンネル / カルシウム遊離 Less

DNA 損傷特異的人工エンドヌクレアーゼによる修復亢進の分子機構Principal Investigator
- Principal Investigator
  
  杉浦重樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Nara Medical University
Enhancing the repair of oxidative DNA damage with an artificial endonucleasePrincipal Investigator
- Principal Investigator
  
  Sugiura Shigeki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Nara Medical University
Application of DNA damage-specific endnucleases which enhance a repair abilityPrincipal Investigator
- Principal Investigator
  
  SUGIURA Shigeki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nara Medical University
Transform the antibodies against DNA lesions into the repair-enhancing reagents of them
- Principal Investigator
  
  MORI Toshio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nara Medical University
Construction of DNA damage-specific endonuclease using monoclonal antibody against DNA damagePrincipal Investigator
- Principal Investigator
  
  SUGIURA Shigeki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nara Medical University
Approaches to enhance a repair ability of UV induced DNA damage by promotion of DNA damage-recognitionPrincipal Investigator
- Principal Investigator
  
  SUGIURA Shigeki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nara Medical University
Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -
- Principal Investigator
  
  KISHIMOTO Toshifumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells
- Principal Investigator
  
  NAKAMURA Yu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Molecular coupling required for intracellular calcium release that regulates synaptic depression
- Principal Investigator
  
  KATO Nobuo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Kyoto University
DNA複製におけるイニシエーター蛋白の役割Principal Investigator
- Principal Investigator
  
  杉浦重樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
Analysis of initiatin and its regulation in in vitro replication system of plasmid DNA
- Principal Investigator
  
  YAMAGUCHI Kazuo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Kanazawa University

All 2014 2013 2012

All Journal Article Presentation

[Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  T. Iwamoto, P.J. Brooks, T. Nishiwaki, K. Nishimura, N. Kobayashi, S. Sugiura and T. Mori.
- Journal Title
  
  Photochem. Photobiol.
  
  Volume: xx Issue: 4 Pages: 829-836
- DOI
  10.1111/php.12239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23510081, KAKENHI-PROJECT-23591626, KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-24790895, KAKENHI-PROJECT-26550042
[Journal Article] TNF-alpha stimulates efficient JC virus replication in neuroblastoma cells2014
- Author(s)
  Nukuzuma, S. Nakamichi, K. Kameoka, M. Sugiura, S. Nukuzuma, C. Tasaki, T. Takegami, T.
- Journal Title
  
  J Med Virol
  
  Volume: XX Issue: 12 Pages: 2026-2032
- DOI
  10.1002/jmv.23886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-25430119
[Journal Article] Suppressive effect oh PARP-1 inhibitor on JC virus replication in vitro2013
- Author(s)
  Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., and Takegami, T.
- Journal Title
  
  J. Med. Virol.
  
  Volume: 85 Pages: 132-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052
[Journal Article] Suppressive effect of PARP-1 inhibitor on JC virus replication in vitro2013
- Author(s)
  Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., Takegami, T.
- Journal Title
  
  J Med Virol
  
  Volume: 85 Issue: 1 Pages: 132-137
- DOI
  10.1002/jmv.23443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052
[Journal Article] Exogenious human immunodeficiency virus-1 protein, Tat, enhances replication of JC virus efficiently in neuroblastoma cell lines2012
- Author(s)
  Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., Miyoshi, I., and Takegami, T.
- Journal Title
  
  J Med Virol
  
  Volume: 84 Issue: 4 Pages: 555-561
- DOI
  10.1002/jmv.23239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-Cyclo-2'deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  Iwamoto, T., Brooks, P. J., Kobayashi, N., Sugiura, S., and Mori, T.
- Organizer
  International symposium on xeroderma pigmentosum and related diseases : Disorderes of DNA damage response-Bench to -bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’- cyclo- 2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  Iwamoto, T. Brooks, P. J. Kobayashi, N. Sugiura, S. and Mori, T.
- Organizer
  nternational symposium on xeroderma pigmentosum and related diseases: Disorders of DNA damage response - Bench to bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] PARP-1阻害剤のin vitroにおけるウイルス増殖抑制効果について2013
- Author(s)
  奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、田崎隆史、竹上勉
- Organizer
  日本ウイルス学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] PARP-1 阻害剤の in vitro における JC ウイルス増殖抑制効果について2013
- Author(s)
  奴久妻聡、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、田崎隆史、竹上勉
- Organizer
  日本ウイルス学会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] HIV-1 Tatによる神経芽細胞腫でのJCウイルス増殖促進2012
- Author(s)
  奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、竹上勉
- Organizer
  日本ウイルス学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] HIV-1 Tatによる神経芽細胞腫でのJCウイルス増殖促進2012
- Author(s)
  奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、竹上勉
- Organizer
  日本ウイルス学会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24651052

1. MORI Toshio (10115280)

# of Collaborated Projects: 8 results

# of Collaborated Products: 3 results
2. YOSHINO Hiroaki (10347560)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAKAMURA Yu (70291440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KISHIMOTO Toshifumi (60201456)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KATO Nobuo (10152729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMAGUCHI Kazuo (00019879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 織田昌幸 (20318231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IWAMOTO Takaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. HIGASHI Nobutake

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sugiura Shigeki 杉浦 重樹

杉浦 重樹 スギウラ シゲキ

SUGIURA Shigeki 杉浦 重樹

Research Projects

Research Products

Co-Researchers

DNA 損傷特異的人工エンドヌクレアーゼによる修復亢進の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Enhancing the repair of oxidative DNA damage with an artificial endonucleasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of DNA damage-specific endnucleases which enhance a repair abilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transform the antibodies against DNA lesions into the repair-enhancing reagents of them

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of DNA damage-specific endonuclease using monoclonal antibody against DNA damagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Approaches to enhance a repair ability of UV induced DNA damage by promotion of DNA damage-recognitionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular coupling required for intracellular calcium release that regulates synaptic depression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA複製におけるイニシエーター蛋白の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of initiatin and its regulation in in vitro replication system of plasmid DNA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TNF-alpha stimulates efficient JC virus replication in neuroblastoma cells2014

Author(s)

Journal Title

Sugiura Shigeki 杉浦重樹

杉浦重樹スギウラシゲキ

SUGIURA Shigeki 杉浦重樹