UMEHARA Kaoru 梅原薫

… Alternative Names

梅原薫ウメハラカオル

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Researcher Number	40185070
Other IDs
Affiliation (Current)	2025: 横浜薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2016: 静岡県立大学, 薬学研究院, 准教授 2010 – 2015: 静岡県立大学, 薬学部, 講師 2008: 静岡県立大学, 薬学部, 講師 2006 – 2007: Univ.of Shizuoka, School of Pharm.Sci., Dept of Pharmacognosy, Research Associate, 薬学部, 助教 2001 – 2006: 静岡県立大学, 薬学部, 助手 1995: 静岡県立大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Natural medicines / 医薬分子機能学 Except Principal Investigator Living organism molecular science / Natural medicines / Bioorganic chemistry / Biomolecular chemistry / Environmental pharmacy
Keywords	Principal Investigator タイ薬用植物 / リーシュマニア / 熱帯風土病 / in silico スクリーニング / リグナン / フラボノイド / デング熱 / リーシュマニア症 / 薬用植物 / lignan … More / flavonoid / leishmania / dengue / NTD / medicinal plant … More Except Principal Investigator Rheum palmatum / flavonoid / squalene / Hopene synthase / triterpene / chalcone synthase / aloesone / polyketide / CHS / 生合成 / 生理活性 / 酵素工学 / 生物活性試験 / 昆虫 / 化学構造解析 / 薬効成分 / 薬用植物 / 伝統医学 / 国際情報交換 / モンゴル国 / squalene : hopene cyclase / aloe / plant polyketide synthase / chalcone / decarboxylation / Benzalacetone synthase / Ipomoea / Stilbene synthase / Chalocone synthase / Plant polyketide synthase / Rheum Palmatum / Ipomoeapurpurea / 植物ポリケタイド / Rheum palmatun / 脱炭酸 / ベンザルアセトン合成酵素 / サツマイモ属 / スチルベン合成酵素 / カルコン合成酵素 / 植物ポリケタイド合成酵素 / OAC / polyketide synthase / Type III PKS / X線結晶構造解析 / 閉環酵素 / 植物 / タンパク質結晶構造解析 / 反応機構 / ポリケタイド / 薬用資源学 / 天然資源 / しゃっくり / 柿 / 臨床効果 / 神経伝達物質 / がん患者 / 吃逆 / 柿蔕 / バイオテクノロジー / プレニル基転移酵素 / テレトニン / 酵素 / テルペン環化酵素 / 分子多様性 / メロテルペノイド / biosynthesis / ゲノム / flavoncid / chalcone synthas Less

Bioactive compounds from Mongolian traditional medicinal plants and their effects evaluations to living organisms using insect
- Principal Investigator
  
  MURATA Toshihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Natural medicines
- Research Institution
  Tohoku Medical and Pharmaceutical University
Unification of biosynthetic pathways of a variety of plant polyketides
- Principal Investigator
  
  Noguchi Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  University of Shizuoka
Anti-NTDs compounds from tropical medicinal plantsPrincipal Investigator
- Principal Investigator
  
  Umehara Kaoru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  University of Shizuoka
Evaluation of Kaki Calyx as natural resources
- Principal Investigator
  
  ISHII YASUKO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
Generating molecular diversity by the wide range of polyketide synthases
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of Shizuoka
植物ポリケタイド生合成工学による分子多様性の創出
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of Shizuoka
Combinatorial Biosynthesis of Plant Polyketides and Polyprenoids
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of Shizuoka
Formation of unnatural novel polyketides and isoprenoids from alternate and/or nonphysiological substrate by the engineered plant enzymes
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of Shizuoka
Functional diversity of chalcone synthase
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  University of Shizuoka
白血病細胞分化誘導活性を有する生薬成分に関する研究Principal Investigator
- Principal Investigator
  
  梅原薫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  University of Shizuoka

All 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Furofuran Lignan Glucosides with Estrogen-Inhibitory Properties from the Bangladeshi Medicinal Plant Terminalia citrina2016
- Author(s)
  Md. Abdul Muhit, Kaoru Umehara, Kanami Mori-Yasumoto, Hiroshi Noguchi†
- Journal Title
  
  Journal of Natural Products
  
  Volume: 79 Issue: 5 Pages: 1-10
- DOI
  10.1021/acs.jnatprod.5b01042
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460126, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397
[Journal Article] Abietane-type diterpenoids from the roots of Caryopteris mongolica2016
- Author(s)
  Toshihiro Murata, Yoshinobu Ishikawa, Erdenebileg Saruul, Erdenechimeg Selenge, Kenroh Sasaki, Kaoru Umehara, Fumihiko Yoshizaki, Javzan Batkhuu
- Journal Title
  
  Phytochemistry
  
  Volume: 130 Pages: 152-158
- DOI
  10.1016/j.phytochem.2016.05.011
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860068, KAKENHI-PROJECT-16K08199
[Journal Article] Phenolic constituents of the Bangladeshi medicinal plant Pothos scandens and their anti-estrogenic, hyaluronidase inhibition, and histamine release inhibitory activities2016
- Author(s)
  Md. Abdul Muhit, Masahiro Izumikawa, Kaoru Umehara, Hiroshi Noguchi
- Journal Title
  
  Phytochemistry
  
  Volume: 121 Pages: 30-37
- DOI
  10.1016/j.phytochem.2015.10.009
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460126
[Journal Article] Structure and Antioxidant Activity Relationships of Isoflavonoids from Dalbergia parviflora2014
- Author(s)
  Promden W, Monthakantirat O, Umehara K, Noguchi H, De-Eknamkul W
- Journal Title
  
  Molecules
  
  Volume: 19 Issue: 2 Pages: 2226-2237
- DOI
  10.3390/molecules19022226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-25460126
[Journal Article] Cytotoxic and immunomodulatory effects of polyhydroxyoctane isolated from Lentinus polychrous mycelia.2014
- Author(s)
  Fangkrathok N, et al.
- Journal Title
  
  J. Nat. Med
  
  Volume: 68 Issue: 2 Pages: 302-309
- DOI
  10.1007/s11418-013-0797-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-25460126
[Journal Article] Bioactive ergostanoids and a new polyhydroxyoctane from Lentinus polychrous mycelia and their inhibitory effects on E2-enhanced cell proliferation of T47D cells2013
- Author(s)
  Fangkrathok, Niramai; Sripanidkulchai, Bungorn; Umehara, Kaoru; Noguchi, Hiroshi
- Journal Title
  
  Natural Product Research
  
  Volume: 27 Pages: 1611-1619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460126
[Journal Article] Flavonoid and stilbenoid production in callus cultures of Artocarpus lakoocha2012
- Author(s)
  S. Maneechai, W. De-Eknamkul, K. Umehara, H. Noguchi, K. Likhitwitayawuid
- Journal Title
  
  Phytochemistry
  
  Volume: 81 Pages: 42-49
- DOI
  10.1016/j.phytochem.2012.05.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] Anti-dengue Potential of Isoflavonoids from Thai Medicinal Plant2016
- Author(s)
  Kaoru Umehara, Orawan Monthakantirat, Wanchai-De-Eknamkul, Kazuya I.P.J. Hidari, Noorsaadah Abd. Rahman, Hiroshi Noguchi
- Organizer
  NATPRO 6
- Place of Presentation
  Khon Kaen, Thailand
- Year and Date
  2016-01-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] 抗リーシュマニア活性を有するタイ薬用植物、 Diospyros mollis 中の成分研究2016
- Author(s)
  諏訪間崇治, 渡邊敬介, 梅原薫, 安元加奈未, Orawan MONTHAKANTIRAT, Prathan LUECHA, 野口博司
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] Chemical constituents and its DPPH-free radical scavenging activity from Mitrephora winitii Craib (Annonaceae)2016
- Author(s)
  Boonsong WUNGSINTAWEEKUL, Tanawat CHAOWASKU, 梅原薫, 野口博司
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物 Asparagus racemosus 中アルカロイドの estrogen/anti-estrogen, hyaluronidase 阻害作用2015
- Author(s)
  泉川雅裕, 菅谷香帆, 大石早人, Boonsong WUNGSINTAWEEKUL, 梅原薫, 野口博司
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] Estrogenic and/or anti-estrogenic lignan glycosides from Terminalia citrina2015
- Author(s)
  Md Abdul Muhit, Kaoru Umehara, Hiroshi Noguchi
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] バングラデシュ薬用植物 Pothos scandens 中の estrogen/anti-estrogen 様物質の検索2015
- Author(s)
  Md. Abdul MUHIT, 梅原薫, 野口博司
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] Effect of Miroestrol on D-galactose-induced Oxidative Stress in Mice Brain2015
- Author(s)
  Orawan Monthakantirat, Nawapol Tumjaitong, Natcha Naveenavakun, Yaowared Chulikhit, Kaoru Umehara, Wanchai De-Eknamkul, Noguchi Hiroshi
- Organizer
  ISPSA 2015
- Place of Presentation
  徳島
- Year and Date
  2015-08-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物 Artabotrys hexapetalus 由来の anti-estrogen 様物質の探索2015
- Author(s)
  戸塚統子、Orawan Monthakantirat、梅原　薫、野口博司
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] バングラデシュ薬用植物 Terminalia citrina 中の estrogen 様物質の探索2015
- Author(s)
  小林広樹, MD ABDOUL MUHIT, 梅原薫, 野口博司
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物 Artocarpus lakoocha (Moraceae) 中の estrogen/anti-estrogen 様物質の探索2015
- Author(s)
  箕浦翔、梅原　薫、野口博司、Orawan Monthakantirat
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物 Solanum torvum 中の estrogen/anti-estrogen 様物質の探索2015
- Author(s)
  二木裕紀、梅原　薫、野口博司、Arunee Simaratanamongkol
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物 Anaxagorea luzonensis 由来の estrogen/anri-estrohgen 用物質の検索2014
- Author(s)
  長嶋香織、梅原　薫、野口博司、Boondong Wungsintaweekul
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物 Pueraria candollei var. mirifica 中の estrogen/anti-estrogen 用化合物の探索2014
- Author(s)
  梅原　薫、野口博司、Orawan Monthakantirat
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物 Asparagus racemosus 中の estrogen/anti-estrogen 用活性物質の探索2014
- Author(s)
  大石早人、梅原　薫、野口博司、Boonsong Wungsintaweeekul
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物由来イソフラボノイドの抗デング熱作用2014
- Author(s)
  梅原　薫、左　一八、安倍智子、Orawan Monthakantirat、Wanchai De-Eknamkul、Noorsaadah Abd. Rahman、鈴木　隆、野口博司
- Organizer
  第20回天然薬物の開発と応用シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] タイ薬用植物 Dalbergia parviflora 由来 isoflavonoids の抗デング熱活性2013
- Author(s)
  梅原　薫, Orawan MONTHAKANTIRAT, Wanchai DE-EKNAMKUL, 左　一八、鈴木　隆、野口博司
- Organizer
  日本生薬学会第60回年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] 抗デングウイルス活性を有するキノコ成分の性状解析2013
- Author(s)
  安倍　智子、左　一八、梅原　薫、VIKINESWARY SABARATNAM、森田　公一、野口博司、鈴木　隆
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] オオヒラタケ熱水抽出物によるデングウイルス感染阻害2013
- Author(s)
  安倍智子、左　一八、梅原　薫、Sabaratnam S. Vikineswary、森田公一、野口博司
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] Estrogenic/anti-estrogenic isoflavonoids in Thai medicinal plants.
- Author(s)
  梅原　薫
- Organizer
  The 3rd Current Drug Development International Conference
- Place of Presentation
  Thailand
- Year and Date
  2014-05-01 – 2014-05-03
- Invited
- Data Source
  KAKENHI-PROJECT-25460126
[Presentation] Anti Dengue and Leishmanicidal Activities of Flavonoids from Thai Medicinal plants
- Author(s)
  26.Kaoru Umehara, Tomoko Abe, Kazuya Hidari, Takashi Suzuki, Kanami Mori-Yasumoto, Setsuko Sekita, Orawan Monthakantirat, Wanchai De-Eknamkul, Hiroshi Noguchi
- Organizer
  27th International Conference on Polyphenol
- Place of Presentation
  名古屋
- Year and Date
  2014-09-02 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-25460126

1. NOGUCHI Hiroshi (60126141)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
2. ABE Ikuro (40305496)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. WATANABE KENJI (50360938)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. ISHII YASUKO (00106436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MORITA HIROYUKI (20416663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YASUMOTO Kanami (70412393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. SUZUKI Takashi (20240947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. HIDARI Kazuya (20260226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. MURATA Toshihiro (70458214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. ISHIKAWA Yoshinobu (00305004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SUGANUMA Keisuke (60772184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SASAKI Kenroh (90244970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 久城哲夫 (80373299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 飯田滋 (30012777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 関田節子 (90171339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NOGE Ichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KATO Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. BATKHUU Javzan

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. DAVAAPUREV Bekh-Ochir

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ODONTUYA Gendaram

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SELENGE Erdenechimeg

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

UMEHARA Kaoru 梅原 薫

梅原 薫 ウメハラ カオル

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Anti-NTDs compounds from tropical medicinal plantsPrincipal Investigator

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白血病細胞分化誘導活性を有する生薬成分に関する研究Principal Investigator

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[Journal Article] Furofuran Lignan Glucosides with Estrogen-Inhibitory Properties from the Bangladeshi Medicinal Plant Terminalia citrina2016

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[Journal Article] Abietane-type diterpenoids from the roots of Caryopteris mongolica2016

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[Journal Article] Phenolic constituents of the Bangladeshi medicinal plant Pothos scandens and their anti-estrogenic, hyaluronidase inhibition, and histamine release inhibitory activities2016

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[Journal Article] Structure and Antioxidant Activity Relationships of Isoflavonoids from Dalbergia parviflora2014

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[Journal Article] Cytotoxic and immunomodulatory effects of polyhydroxyoctane isolated from Lentinus polychrous mycelia.2014

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UMEHARA Kaoru 梅原薫

梅原薫ウメハラカオル

[Journal Article] Bioactive ergostanoids and a new polyhydroxyoctane from Lentinus polychrous mycelia and their inhibitory effects on E2-enhanced cell proliferation of T47D cells2013