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UMEHARA Kaoru  梅原 薫

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… Alternative Names

梅原 薫  ウメハラ カオル

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Researcher Number 40185070
Other IDs
Affiliation (Current) 2025: 横浜薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2016: 静岡県立大学, 薬学研究院, 准教授
2010 – 2015: 静岡県立大学, 薬学部, 講師
2008: 静岡県立大学, 薬学部, 講師
2006 – 2007: Univ.of Shizuoka, School of Pharm.Sci., Dept of Pharmacognosy, Research Associate, 薬学部, 助教
2001 – 2006: 静岡県立大学, 薬学部, 助手
1995: 静岡県立大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Natural medicines / 医薬分子機能学
Except Principal Investigator
Living organism molecular science / Natural medicines / Bioorganic chemistry / Biomolecular chemistry / Environmental pharmacy
Keywords
Principal Investigator
タイ薬用植物 / リーシュマニア / 熱帯風土病 / in silico スクリーニング / リグナン / フラボノイド / デング熱 / リーシュマニア症 / 薬用植物 / lignan … More / flavonoid / leishmania / dengue / NTD / medicinal plant … More
Except Principal Investigator
Rheum palmatum / flavonoid / squalene / Hopene synthase / triterpene / chalcone synthase / aloesone / polyketide / CHS / 生合成 / 生理活性 / 酵素工学 / 生物活性試験 / 昆虫 / 化学構造解析 / 薬効成分 / 薬用植物 / 伝統医学 / 国際情報交換 / モンゴル国 / squalene : hopene cyclase / aloe / plant polyketide synthase / chalcone / decarboxylation / Benzalacetone synthase / Ipomoea / Stilbene synthase / Chalocone synthase / Plant polyketide synthase / Rheum Palmatum / Ipomoeapurpurea / 植物ポリケタイド / Rheum palmatun / 脱炭酸 / ベンザルアセトン合成酵素 / サツマイモ属 / スチルベン合成酵素 / カルコン合成酵素 / 植物ポリケタイド合成酵素 / OAC / polyketide synthase / Type III PKS / X線結晶構造解析 / 閉環酵素 / 植物 / タンパク質結晶構造解析 / 反応機構 / ポリケタイド / 薬用資源学 / 天然資源 / しゃっくり / 柿 / 臨床効果 / 神経伝達物質 / がん患者 / 吃逆 / 柿蔕 / バイオテクノロジー / プレニル基転移酵素 / テレトニン / 酵素 / テルペン環化酵素 / 分子多様性 / メロテルペノイド / biosynthesis / ゲノム / flavoncid / chalcone synthas Less
  • Research Projects

    (10 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (21 People)
  •  Bioactive compounds from Mongolian traditional medicinal plants and their effects evaluations to living organisms using insect

    • Principal Investigator
      MURATA Toshihiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Natural medicines
    • Research Institution
      Tohoku Medical and Pharmaceutical University
  •  Unification of biosynthetic pathways of a variety of plant polyketides

    • Principal Investigator
      Noguchi Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      University of Shizuoka
  •  Anti-NTDs compounds from tropical medicinal plantsPrincipal Investigator

    • Principal Investigator
      Umehara Kaoru
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Natural medicines
    • Research Institution
      University of Shizuoka
  •  Evaluation of Kaki Calyx as natural resources

    • Principal Investigator
      ISHII YASUKO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental pharmacy
    • Research Institution
      University of Shizuoka
  •  Generating molecular diversity by the wide range of polyketide synthases

    • Principal Investigator
      NOGUCHI Hiroshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Living organism molecular science
    • Research Institution
      University of Shizuoka
  •  植物ポリケタイド生合成工学による分子多様性の創出

    • Principal Investigator
      NOGUCHI Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      University of Shizuoka
  •  Combinatorial Biosynthesis of Plant Polyketides and Polyprenoids

    • Principal Investigator
      NOGUCHI Hiroshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      University of Shizuoka
  •  Formation of unnatural novel polyketides and isoprenoids from alternate and/or nonphysiological substrate by the engineered plant enzymes

    • Principal Investigator
      NOGUCHI Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      University of Shizuoka
  •  Functional diversity of chalcone synthase

    • Principal Investigator
      NOGUCHI Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      University of Shizuoka
  •  白血病細胞分化誘導活性を有する生薬成分に関する研究Principal Investigator

    • Principal Investigator
      梅原 薫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      医薬分子機能学
    • Research Institution
      University of Shizuoka

All 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Furofuran Lignan Glucosides with Estrogen-Inhibitory Properties from the Bangladeshi Medicinal Plant Terminalia citrina2016

    • Author(s)
      Md. Abdul Muhit, Kaoru Umehara, Kanami Mori-Yasumoto, Hiroshi Noguchi†
    • Journal Title

      Journal of Natural Products

      Volume: 79 Issue: 5 Pages: 1-10

    • DOI

      10.1021/acs.jnatprod.5b01042

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460126, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397
  • [Journal Article] Abietane-type diterpenoids from the roots of Caryopteris mongolica2016

    • Author(s)
      Toshihiro Murata, Yoshinobu Ishikawa, Erdenebileg Saruul, Erdenechimeg Selenge, Kenroh Sasaki, Kaoru Umehara, Fumihiko Yoshizaki, Javzan Batkhuu
    • Journal Title

      Phytochemistry

      Volume: 130 Pages: 152-158

    • DOI

      10.1016/j.phytochem.2016.05.011

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860068, KAKENHI-PROJECT-16K08199
  • [Journal Article] Phenolic constituents of the Bangladeshi medicinal plant Pothos scandens and their anti-estrogenic, hyaluronidase inhibition, and histamine release inhibitory activities2016

    • Author(s)
      Md. Abdul Muhit, Masahiro Izumikawa, Kaoru Umehara, Hiroshi Noguchi
    • Journal Title

      Phytochemistry

      Volume: 121 Pages: 30-37

    • DOI

      10.1016/j.phytochem.2015.10.009

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Journal Article] Structure and Antioxidant Activity Relationships of Isoflavonoids from Dalbergia parviflora2014

    • Author(s)
      Promden W, Monthakantirat O, Umehara K, Noguchi H, De-Eknamkul W
    • Journal Title

      Molecules

      Volume: 19 Issue: 2 Pages: 2226-2237

    • DOI

      10.3390/molecules19022226

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-25460126
  • [Journal Article] Cytotoxic and immunomodulatory effects of polyhydroxyoctane isolated from Lentinus polychrous mycelia.2014

    • Author(s)
      Fangkrathok N, et al.
    • Journal Title

      J. Nat. Med

      Volume: 68 Issue: 2 Pages: 302-309

    • DOI

      10.1007/s11418-013-0797-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-25460126
  • [Journal Article] Bioactive ergostanoids and a new polyhydroxyoctane from Lentinus polychrous mycelia and their inhibitory effects on E2-​enhanced cell proliferation of T47D cells2013

    • Author(s)
      Fangkrathok, Niramai; Sripanidkulchai, Bungorn; Umehara, Kaoru; Noguchi, Hiroshi
    • Journal Title

      Natural Product Research

      Volume: 27 Pages: 1611-1619

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Journal Article] Flavonoid and stilbenoid production in callus cultures of Artocarpus lakoocha2012

    • Author(s)
      S. Maneechai, W. De-Eknamkul, K. Umehara, H. Noguchi, K. Likhitwitayawuid
    • Journal Title

      Phytochemistry

      Volume: 81 Pages: 42-49

    • DOI

      10.1016/j.phytochem.2012.05.031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241054
  • [Presentation] Anti-dengue Potential of Isoflavonoids from Thai Medicinal Plant2016

    • Author(s)
      Kaoru Umehara, Orawan Monthakantirat, Wanchai-De-Eknamkul, Kazuya I.P.J. Hidari, Noorsaadah Abd. Rahman, Hiroshi Noguchi
    • Organizer
      NATPRO 6
    • Place of Presentation
      Khon Kaen, Thailand
    • Year and Date
      2016-01-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] 抗リーシュマニア活性を有するタイ薬用植物、 Diospyros mollis 中の成分研究2016

    • Author(s)
      諏訪間 崇治, 渡邊 敬介, 梅原 薫, 安元 加奈未, Orawan MONTHAKANTIRAT, Prathan LUECHA, 野口 博司
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] Chemical constituents and its DPPH-free radical scavenging activity from Mitrephora winitii Craib (Annonaceae)2016

    • Author(s)
      Boonsong WUNGSINTAWEEKUL, Tanawat CHAOWASKU, 梅原 薫, 野口 博司
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物 Asparagus racemosus 中アルカロイドの estrogen/anti-estrogen, hyaluronidase 阻害作用2015

    • Author(s)
      泉川 雅裕, 菅谷 香帆, 大石 早人, Boonsong WUNGSINTAWEEKUL, 梅原 薫, 野口 博司
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] Estrogenic and/or anti-estrogenic lignan glycosides from Terminalia citrina2015

    • Author(s)
      Md Abdul Muhit, Kaoru Umehara, Hiroshi Noguchi
    • Organizer
      日本生薬学会第62回年会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] バングラデシュ薬用植物 Pothos scandens 中の estrogen/anti-estrogen 様物質の検索2015

    • Author(s)
      Md. Abdul MUHIT, 梅原 薫, 野口 博司
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] Effect of Miroestrol on D-galactose-induced Oxidative Stress in Mice Brain2015

    • Author(s)
      Orawan Monthakantirat, Nawapol Tumjaitong, Natcha Naveenavakun, Yaowared Chulikhit, Kaoru Umehara, Wanchai De-Eknamkul, Noguchi Hiroshi
    • Organizer
      ISPSA 2015
    • Place of Presentation
      徳島
    • Year and Date
      2015-08-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物 Artabotrys hexapetalus 由来の anti-estrogen 様物質の探索2015

    • Author(s)
      戸塚統子、Orawan Monthakantirat、梅原 薫、野口博司
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] バングラデシュ薬用植物 Terminalia citrina 中の estrogen 様物質の探索2015

    • Author(s)
      小林 広樹, MD ABDOUL MUHIT, 梅原 薫, 野口 博司
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物 Artocarpus lakoocha (Moraceae) 中の estrogen/anti-estrogen 様物質の探索2015

    • Author(s)
      箕浦 翔、梅原 薫、野口 博司、Orawan Monthakantirat
    • Organizer
      日本生薬学会第62回年会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物 Solanum torvum 中の estrogen/anti-estrogen 様物質の探索2015

    • Author(s)
      二木裕紀、梅原 薫、野口博司、Arunee Simaratanamongkol
    • Organizer
      日本生薬学会第62回年会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物 Anaxagorea luzonensis 由来の estrogen/anri-estrohgen 用物質の検索2014

    • Author(s)
      長嶋香織、梅原 薫、野口博司、Boondong Wungsintaweekul
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物 Pueraria candollei var. mirifica 中の estrogen/anti-estrogen 用化合物の探索2014

    • Author(s)
      梅原 薫、野口博司、Orawan Monthakantirat
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物 Asparagus racemosus 中の estrogen/anti-estrogen 用活性物質の探索2014

    • Author(s)
      大石早人、梅原 薫、野口博司、Boonsong Wungsintaweeekul
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物由来イソフラボノイドの抗デング熱作用2014

    • Author(s)
      梅原 薫、左 一八、安倍智子、Orawan Monthakantirat、Wanchai De-Eknamkul、Noorsaadah Abd. Rahman、 鈴木 隆、野口博司
    • Organizer
      第20回天然薬物の開発と応用シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-11-06
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] タイ薬用植物 Dalbergia parviflora 由来 isoflavonoids の抗デング熱活性2013

    • Author(s)
      梅原 薫, Orawan MONTHAKANTIRAT, Wanchai DE-EKNAMKUL, 左 一八 、鈴木 隆、野口博司
    • Organizer
      日本生薬学会第60回年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] 抗デングウイルス活性を有するキノコ成分の性状解析2013

    • Author(s)
      安倍 智子、左 一八、梅原 薫、VIKINESWARY SABARATNAM、森田 公一、野口博司、鈴木 隆
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] オオヒラタケ熱水抽出物によるデングウイルス感染阻害2013

    • Author(s)
      安倍智子、左 一八、梅原 薫、Sabaratnam S. Vikineswary、森田公一、野口博司
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] Estrogenic/anti-estrogenic isoflavonoids in Thai medicinal plants.

    • Author(s)
      梅原 薫
    • Organizer
      The 3rd Current Drug Development International Conference
    • Place of Presentation
      Thailand
    • Year and Date
      2014-05-01 – 2014-05-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460126
  • [Presentation] Anti Dengue and Leishmanicidal Activities of Flavonoids from Thai Medicinal plants

    • Author(s)
      26.Kaoru Umehara, Tomoko Abe, Kazuya Hidari, Takashi Suzuki, Kanami Mori-Yasumoto, Setsuko Sekita, Orawan Monthakantirat, Wanchai De-Eknamkul, Hiroshi Noguchi
    • Organizer
      27th International Conference on Polyphenol
    • Place of Presentation
      名古屋
    • Year and Date
      2014-09-02 – 2014-09-06
    • Data Source
      KAKENHI-PROJECT-25460126
  • 1.  NOGUCHI Hiroshi (60126141)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 2.  ABE Ikuro (40305496)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  WATANABE KENJI (50360938)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  ISHII YASUKO (00106436)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MORITA HIROYUKI (20416663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YASUMOTO Kanami (70412393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  SUZUKI Takashi (20240947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  HIDARI Kazuya (20260226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 9.  MURATA Toshihiro (70458214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  ISHIKAWA Yoshinobu (00305004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  SUGANUMA Keisuke (60772184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SASAKI Kenroh (90244970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  久城 哲夫 (80373299)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  飯田 滋 (30012777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  関田 節子 (90171339)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  NOGE Ichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KATO Yuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  BATKHUU Javzan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  DAVAAPUREV Bekh-Ochir
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ODONTUYA Gendaram
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SELENGE Erdenechimeg
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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