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Suzuki Hideharu  鈴木 英治

ORCIDConnect your ORCID iD *help
… Alternative Names

SUZUKI Hideharu  鈴木 英治

鈴木 英治  スズキ ヒデハル

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Researcher Number 40187753
Other IDs
External Links
Affiliation (Current) 2025: 帝京平成大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2014: 帝京平成大学, 薬学部, 教授
2012 – 2013: 東邦大学, 薬学部, 准教授
2005 – 2007: 東邦大学, 薬学部, 講師
2000 – 2002: 東邦大学, 薬学部, 講師
1996 – 1998: 東邦大学, 薬学部, 助手
1988 – 1993: 東邦大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Drug development chemistry
Except Principal Investigator
Chemical pharmacy / Living organism molecular science
Keywords
Principal Investigator
繊維化阻害 / ホスホン酸 / 有機合成 / 多価フェノール / グルコサミン酸 / ベンゾフラン / 繊維化阻害剤 / 凝集阻害剤 / アミロイドベータ / アルツハイマー … More
Except Principal Investigator
… More Alzet / リゼルギン酸 / インドール / 光学活性 / Radical Cyclization, / Vinylation, / Assymetric Reduction, / 4-Bromoindole, / Allylation, / Lysergic Acid, / Palldium Catalyst, / デヒドロトリプトファン誘導体 / パラジウム触媒 / 有機スズ化合物 / 4-ブロモインド-ル / トリプトファン / 不整還元 / デヒドロトリプトンファン / 4ーブロモインド-ル / アリル化反応 / パラジウム / 不斉還元 / デヒドロトリプトファン / transgenic mouse / in vivo activity / quartz-crystal microbalance / in vitro activity / aggregation inhibitor / amyloid β pentide / 水晶発振子マイクロバランス / 培養細胞 / 水晶発振子ミクロ天秤 / 凝集乖離能 / 分子認識 / 会合阻害剤 / アミロイドベータ蛋白 / Heck reaction / alkylindole / acylindole / benztryptophan / Reissert indole synthesis / lysergic acid / indole / canthine-6-one / スルホンアミド / N-acylation / ene-diamine / DMAT / バッカクアルカロイド / キノロン / β-カルボリン / 閉環反応 / ベンズインドール / Heck反応 / アルキルインドール / アシルインドール / ベンズトリプトファン / Reissertインドール合成 / リゼルグ酸 / カンチン-6-オン / Hymenin / Bromination / Acylation / Regiospecific / Alkaloid / Indole / Pyrrole / インド-ル / ピロ-ル / ベックマン転位 / ウィティッヒ反応 / カルボリンアルカロイド / 脱ブロム化 / ハイメニン / ブロム化 / アシル化 / 位置特異的 / アルカロイド / ピロール / トランス-アセチル化 / N,N-ジアセチルアニリン / N-アシル化 / N-アセチル化 / オルトトリフルオロメチルアニリン / オルト置換アニリン / ねじれ / 化学選択的アシル化 / 不斉アシル化 / ラセミ化 / イミド / N-C軸不斉 / オルト置換ジアシルアニリン Less
  • Research Projects

    (6 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (7 People)
  •  Development of amyloid beta aggregation inhibitor for therapeutics of Alzheimer diseasePrincipal Investigator

    • Principal Investigator
      SUZUKI Hideharu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Teikyo Heisei University
      Toho University
  •  Development of aggregation disrupters for amyloid proteins

    • Principal Investigator
      OKUNO Hiroaki
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Toho University
  •  Development of New Reactivities of Indole Nucleus and its Application to Syntheses of Natural Products

    • Principal Investigator
      MURAKAMI Yasuoki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Toho University
  •  オルト置換アニリンのN,N-ジアセチル化その立体化学への応用

    • Principal Investigator
      MURAKAMI Yasuoki
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Toho University
  •  Synthetic Study of Naturally Occurring Indoles Possessing Various Substituents on Benzene Moiety.

    • Principal Investigator
      MURAKAMI Yasuoki
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      TOHO UNIVERSITY
  •  Palladium Catalyzed Direct Allylation of Aromatic Bromides and its Application.

    • Principal Investigator
      YOKOYAMA Yuusaku
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Toho University

All 2014 2013 2012 2008 2007 2005 Other

All Journal Article Presentation Patent

  • [Journal Article] Benzoyl methyl phosphates as efficient reagents in the one- pot tandem approach for the synthesis of 2-phenylbenzimidazoles in water.2014

    • Author(s)
      Hikawa, Hidemasa; Imani, Maki; Suzuki, Hideharu; Yokoyama, Yuusaku; Azumaya, Isao,
    • Journal Title

      RSC Advances

      Volume: 4(8) Issue: 8 Pages: 3768-3773

    • DOI

      10.1039/c3ra46749j

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] Mechanistic studies for synthesis of bis(indolyl) methanes: pd- catalyzed C- H activation of indole- carboxylic acids with benzyl alcohols in water. Hikawa,2013

    • Author(s)
      Hikawa, Hidemasa; Suzuki, Hideharu; Yokoyama, Yuusaku; Azumaya, Isao,
    • Journal Title

      Catalysts (2013), 3(2), 486-500.

      Volume: 3(2) Issue: 2 Pages: 486-500

    • DOI

      10.3390/catal3020486

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] Au(III) /TPPMS- Catalyzed Benzylation of Indoles with Benzylic Alcohols in Water.2013

    • Author(s)
      Hikawa, Hidemasa; Suzuki, Hideharu; Azumaya, Isao,
    • Journal Title

      Journal of Organic Chemistry (2013), 78(23), 12128-12135.

      Volume: 78(23) Issue: 23 Pages: 12128-12135

    • DOI

      10.1021/jo402151g

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] N- Benzylation /Benzylic C- H Amidation Cascade by the (η3- Benzyl) palladium System in Aqueous Media: An Effective Pathway for the Direct Construction of 3- Phenyl- 3, 4- dihydro- (2H) - 1, 2, 4- benzothiadiazine 1, 1-Dioxides2013

    • Author(s)
      Hikawa, Hidemasa; Matsuda, Naoya; Suzuki, Hideharu; Yokoyama, Yuusaku; Azumaya, Isao,
    • Journal Title

      ADVANCED SYNTHESIS & CATALYSIS

      Volume: 355(11-12) Issue: 11-12 Pages: 2308-2320

    • DOI

      10.1002/adsc.201300317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147, KAKENHI-PROJECT-25460026
  • [Journal Article] A practical regioselective synthesis of alkylthio- or arylthioindoles without the use of smelly compounds such as thiols.2013

    • Author(s)
      Hamashima, Toshihiko; Mori, Yoshiaki; Sawada, Kazunori; Kasahara, Yuko; Murayama, Daisuke; Kamei, Yuto; Okuno, Hiroaki; Yokoyama, Yuusaku; Suzuki, Hideharu,
    • Journal Title

      Chemical & Pharmaceutical Bulletin (2013), 61(3), 292-303.

      Volume: 61(3) Pages: 292-303

    • NAID

      130002460113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] A Practical Regioselective Synthesis of Alkylthio- or Arylthioindoles without the Use of Smelly Compounds Such as Thiols2013

    • Author(s)
      Toshihiko Hamashima, Yoshiaki Mori, Kazunori Sawada, Yuko Kasahara, Daisuke Murayama, Yuto Kamei, Hiroaki Okuno, Yuusaku Yokoyama, Hideharu Suzuki
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 61 Issue: 3 Pages: 292-303

    • DOI

      10.1248/cpb.c12-00882

    • NAID

      130002460113

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2, 3- dioxygenase (IDO) inhibitors.2013

    • Author(s)
      Tanaka, Minoru; Li, Xin; Hikawa, Hidemasa; Suzuki, Takafumi; Tsutsumi, Katsuhiko; Sato, Masashi; Takikawa, Osamu; Suzuki, Hideharu; Yokoyama, Yuusaku,
    • Journal Title

      Bioorganic & Medicinal Chemistry (2013), 21(5), 1159-1165.

      Volume: 21(5) Issue: 5 Pages: 1159-1165

    • DOI

      10.1016/j.bmc.2012.12.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147, KAKENHI-PROJECT-24590397
  • [Journal Article] Synthesis of VIP- lipopeptide using a new linker to modify liposomes: towards the development of a drug delivery system for active targeting.2013

    • Author(s)
      Masaka, Toru; Matsuda, Takuya; Li, Yingpeng; Koide, Yuki; Takami, Akira; Yano, Kenji; Imai, Ryosuke; Ichihara, Risa; Yagi, Nobuhiro; Suzuki, Hideharu;
    • Journal Title

      Chemical & Pharmaceutical Bulletin (2013), 61(11), 1184-1187.

      Volume: 61(11) Pages: 1184-1187

    • NAID

      130003360912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] Chemoselective Benzylation of Unprotected Anthranilic Acids with Benzhydryl Alcohols by Water- Soluble Au(III) /TPPMS in Water.2013

    • Author(s)
      Hikawa, Hidemasa; Suzuki, Hideharu; Yokoyama, Yuusaku; Azumaya, Isao,
    • Journal Title

      Journal of Organic Chemistry

      Volume: 78(13) Issue: 13 Pages: 6714-6720

    • DOI

      10.1021/jo401064f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] Pd-Catalyzed Benzylic C-H Amidation with Benzyl Alcohols in Water: A Strategy To Construct Quinazolinones2012

    • Author(s)
      Hidemasa Hikawa, Yukari Ino, Hideharu Suzuki, Yuusaku Yokoyama
    • Journal Title

      The Journal of Organic Chemistry

      Volume: 77 Issue: 16 Pages: 7046-7051

    • DOI

      10.1021/jo301282n

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] Synthesis and Evaluation of 4-Aryl-2(1H)-quinolinones as Potent Amyloid β Fibrillogenesis Inhibitors2012

    • Author(s)
      Yoko Shimokawa
    • Journal Title

      Heterocycles

      Volume: 85 Issue: 8 Pages: 1933-1940

    • DOI

      10.3987/com-12-12506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590022, KAKENHI-PROJECT-24590147
  • [Journal Article] Development of a New Distyrylbenzene-Derivative Amyloid-β-aggregation and Fibril Formation Inhibitor2012

    • Author(s)
      Hideharu Suzuki, Akihito Ishigami, Ayako Orimoto, Akihiro Matsuyama, Setsuko Handa, Naoki Maruyama, Yuusaku Yokoyama,a Hiroaki Okuno, and Masamichi Nakakoshi
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 60 Issue: 9 Pages: 1164-1170

    • DOI

      10.1248/cpb.c12-00365

    • NAID

      130001852537

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance2007

    • Author(s)
      Okuno, Mori, Okada, Yokoyama, Suzuki
    • Journal Title

      Chemical Biology&Drug Design 69

      Pages: 356-361

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17310132
  • [Journal Article] Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance2007

    • Author(s)
      Okuno, Mori, Okada, Yokoyama and Suzuki
    • Journal Title

      Chemical Biology & Drug Design 69

      Pages: 356-361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17310132
  • [Journal Article] Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance2007

    • Author(s)
      Hiroaki, Okuno, Kanae, Mori, Tomoko, Okada, Yuusaku, Yokoyama, Hideharu, Suzuki
    • Journal Title

      Chemical Biology & Drug Design 69(5)

      Pages: 356-361

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17310132
  • [Journal Article] Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance2007

    • Author(s)
      Hiroaki Okuno, Kanae Mori, Tomoko Okada, Y. Yokoyama, H. Suzuki
    • Journal Title

      Chemical Biology & Drug Design (submitted)

    • Data Source
      KAKENHI-PROJECT-17310132
  • [Journal Article] A New Synthesis of 4-Oxygenated β-carboline Derivatives by Fischer Indolization2005

    • Author(s)
      Suzuki, H., Tsukakoshi, Y., Tachikawa, T., Miura, Y., Adachi, M., Murakaimi Y.
    • Journal Title

      Tetrahedron Letters

      Pages: 3831-3834

    • Data Source
      KAKENHI-PROJECT-17310132
  • [Journal Article] A Total Synthesis of 1-Methoxycanthin-6-one : An Efficient One-Pot Synthesis of the Canthin-6-one Skeleton from b-Carboline-1-carboxyaldehyde2005

    • Author(s)
      Suzuki H, Adachi M, Ebihara Y, Gyoutoku H, Furuya H, Murakami Y, Okuno H
    • Journal Title

      Synthesis

      Pages: 28-32

    • Data Source
      KAKENHI-PROJECT-17310132
  • [Patent] アミロイドベータ凝集阻害作用を有するフェノール誘導体2008

    • Inventor(s)
      奥野、鈴木、石神
    • Industrial Property Rights Holder
      奥野、鈴木、石神、興和(株)
    • Industrial Property Number
      2008-041928
    • Filing Date
      2008-02-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17310132
  • [Patent] アミロイドベータ凝集阻害作用を有するフェノール誘導体2007

    • Inventor(s)
      奥野洋明, 鈴木英治, 石神昭人
    • Industrial Property Rights Holder
      奥野洋明, 鈴木英治, 石神昭人, 興和創薬
    • Industrial Property Number
      2007-044155
    • Filing Date
      2007-02-23
    • Data Source
      KAKENHI-PROJECT-17310132
  • [Presentation] アントラセン骨格をもつボロン酸誘導体の結晶構造および蛍光特性

    • Author(s)
      佐藤ひかり、枡飛雄真、氷川英正、鈴木英治、東屋功
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] Echinosulfone Aの全合成研究

    • Author(s)
      村山大介、濱島利彦、池上蘭、森善昭、氷川英正、横山祐作、鈴木英治
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] 水中でのπーベンジルPdを用いたN-ベンジル化/ベンジル位C-Hアミド化連続反応

    • Author(s)
      氷川英正、松田直也、鈴木英治、横山祐作、東屋功
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] アミロイドβ凝集阻害・繊維溶解作用をもつジアリルベンゾフラン誘導体

    • Author(s)
      鈴木英治,矢島聖也,山口勇樹, 佐々木雄大,中越雅道,石神昭人,津吹政可,横山祐作
    • Organizer
      第30回メディシナルケミストリーシンポジウム
    • Place of Presentation
      タワーホール船堀(東京都)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] グリセリンの不斉アシル化反応

    • Author(s)
      内田有華、深山翔太、氷川英正、鈴木英治、横山祐作、東屋功
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] D-グルコサミンからFmoc固相合成に適したD-グルコサミン酸保護体の合成

    • Author(s)
      丸山慧、田中晴希、小倉有季奈、松山明弘、氷川英正、横山祐作、鈴木英治
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] 新規Aβ凝集阻害剤の開発 ~2-フェニルベンゾフランのホスホン 酸誘導体~

    • Author(s)
      町野有望、丸山慧、田中晴希、柏田歩、中越雅道、津吹政可、氷川英正、鈴木英治、東屋功
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] 紅藻ソゾノハナ由来の抗菌物質MC5-MC-8の全合成と抗菌活性

    • Author(s)
      亀井勇統、濱島利彦、鈴木英治
    • Organizer
      第27回日本水産学会春季大会
    • Place of Presentation
      東京海洋大学品川キャンパス(東京都港区)
    • Year and Date
      2015-03-27 – 2015-03-31
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] インドールを含む芳香族スルホンアミドの結晶構造中に見られる特徴的な分子間相互作用

    • Author(s)
      前埜伊沙恵、片桐幸輔、氷川英正、鈴木英治、東屋功
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] 水中でのグリセリンとMBPの不斉アシル化反応の検討

    • Author(s)
      深山翔太、氷川英正、鈴木英治、横山祐作
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] 水中でのAu(III)TPPMS触媒を用いたインドールのベンジル化反応

    • Author(s)
      氷川英正、鈴木英治、東屋功
    • Organizer
      第40回反応と合成の進歩シンポジウム
    • Place of Presentation
      東北大学川内萩ホール(宮城県仙台市)
    • Year and Date
      2014-11-10 – 2014-11-11
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] 水中でのPd触媒を用いたアニリンのベンジル化

    • Author(s)
      泉京江、井野友加里、氷川英正、鈴木英治、横山祐作、東屋功
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] アルツハイマー病治療薬を目的としたアミロイドβ凝集阻害剤の開発:D-Gluco samic acidを親水性部位とするベンゾフラン誘導体の合成

    • Author(s)
      角田まりえ、町野有望、丸山慧、田中晴希、中越雅道、津吹政可、氷川英正、鈴木英治、東屋功
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24590147
  • 1.  TANI Masanobu (50057733)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  YOKOYAMA Yuusaku (10095325)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  MURAKAMI Yasuoki (20009179)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KONDO Kasuhiro (90277343)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Toshiko (40120323)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  ISHIGAMI Akihito (50270658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  OKUNO Hiroaki (20356710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

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