Noguchi Noriko 野口範子

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NOGUCHI Noriko 野口範子

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Researcher Number	40198578
Other IDs
Affiliation (Current)	2025: 同志社大学, 生命医科学部, 教授
Affiliation (based on the past Project Information) *help	2024: 同志社大学, 生命医科学部, 教授 2013 – 2018: 同志社大学, 生命医科学部, 教授 2004: The University of Tokyo, Research Center for Advanced Science and Technology, Associate Professor, 先端科学技術研究センター, 科学技術振興特任教員(特任助教授) 2003: 東京大学, 先端科学技術研究センター, 科学技術振興特任教員(常勤形態)(特任教授) 1993 – 2000: University of Tokyo, Research Center for Advanced Science and Technology, Resear, 先端科学技術研究センター, 助手 1996: University of Tokyo, Research Center for Advanced Science and Technology, Resear, 先端科学技術センター, 助手 1992: 東京大学, 工学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 59020:Sports sciences-related / Eating habits / 医薬分子機能学 Except Principal Investigator 有機工業化学 / Food science / Medical pharmacy / Circulatory organs internal medicine / 有機工業化学 / Management
Keywords	Principal Investigator 抗酸化物質 / LDL / 酸化 / インスリンシグナル / 運動 / 超硫黄 / シグナル伝達 / 生体分子 / 脳神経疾患 / 脂質 … More / 食品 / 神経変性疾患 / 膜の流動性 / phospho-CaMKII / CaMKII / 酸化ストレス / 膜破綻 / ACAT1 / 24S-ヒドロキシコレステロール / 脂肪滴 / 小胞体ストレス / ビタミンE / アルツハイマー病 / 神経細胞死 / コレステロール / オキシステロール / Cytokine / Antioxidants / Oxidation / Atherosclerosis / Co-culture / サイトカイン / 動脈硬化 / 混合培養 … More Except Principal Investigator ビタミンE / 抗酸化物 / 脂質過酸化 / lipid peroxidation / 動脈硬化 / スピンラベル法 / 低比重リポタンパク / 酸化ストレス / NRF2 / DSCR1 / 酸化劣化 / oxidative damage / free radical / 過酸化物 / セレン / エブセレン / 自動酸化 / 低比重リポ蛋白質 / ヒドロペルオキシド / トコフェロール / 抗酸化食品 / クロスリンカー / セレン運搬作用 / セレノプロテインP / 回収エンドソーム / リソソーム / 細胞内輸送 / 糖尿病 / 栄養生化学 / セレノプロテイン / 中和抗体 / インスリン / 膵β細胞 / 受容体 / トランスポーター / 酸化DJ-1 / ドパミン神経 / ELISA / 早期診断 / モノクローナル抗体 / バイオマーカー / DJ-1 / パーキンソン病 / NFATC / TRANSCRIPTINAL FACTORS / ADHESION MOLECULE / ENDOTHELIAL CELL / ATHEORSCLEROSIS / Tie-2 / target transgenic mouse / TNF-a / トロンビン / 血管内皮細胞 / マイクロアレイ / 炎症 / ラフト / コレステロール / Rac1 / GATA / NFATc / 転写因子 / 接着因子 / 内皮細胞 / oxygen / antioxidants / plasma / low density lipoprotein / Lipids / 酸素ラジカル / 蛍光分析 / 化学発光 / ラジカル / 酸素 / 血漿 / 油脂 / plasma membrane / cultured cells / liposumes / spin label technique / election spin resonance / 脂質二分子膜 / 不均一系 / ESRスピンラベル法 / 細胞膜 / 形質膜 / 細胞 / リポソーム / 脂質過酸化反応 / 電子スピン共鳴 / ebselen / peroxide / selenium / antioxidant / エプセレン / 酸素毒性 / フリーラジカル / 脂質酸化 / Atherosclerosis / Selen compounds / Carbazoles / Phenols / Vitamin E / Antioxidant / Lipid peroxidation / カルバゾール / フェノール / 抗酸化剤 / 酸化 / セレン化合物 / カルバゾール類 / フェノール類 / ワーク・ライフ・バランス / 若手研究者 / 自然科学系女性研究者 / プロフェッショナルコンフィデンス / ワークライフバランス / キャリア継続 / 社会系心理学 / 自然科学 / 女性研究者 / キャリア形成 / プロフェッショナル・コンフィデンス / 脂質過酸化物 / アポ蛋白 / 酸化変性 / LDL / フリーラディカル / 脳脂質 / 脳ホモジネート / 酸素傷害 / 神経細胞 Less

The mechanism of the regulation for optimized protective effect of exercise against diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  野口範子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Doshisha University
Mechanism of inhibition of oxysterol-induced Alzheimer's disease by vitamin EPrincipal Investigator
- Principal Investigator
  
  Noguchi Noriko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Doshisha University
Professional Confidence and Career Development for Women in Science, Technology, Engineering and Mathematics
- Principal Investigator
  
  Fujimoto Tetsushi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Management
- Research Institution
  Doshisha University
Development of diagnosis and treatment of Parkinson disease at early stage using novel biomarker oxidized DJ-1
- Principal Investigator
  
  Yoshiro Saito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Doshisha University
Selenium-transport mechanism of selenoprotein P
- Principal Investigator
  
  Saito Yoshiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Doshisha University
Activation of Arterial Wall Cells during Atherogenesis : A study using a in vitor co-culture model system
- Principal Investigator
  
  KODAMA Tatsuhiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Evaluation of antioxidant activity against atherosclerosis using co-culture systemPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Noriko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Research Center for Advanced Science and Technology, University of Tokyo
Measuring Lipid peroxidation in the matrix using ESR spin labeling
- Principal Investigator
  
  TAKAHASHI Mareyuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  有機工業化学
- Research Institution
  The University of Tokyo
Development and Application of Quantitative Evaluation System for Oxidative Damage of Lipids
- Principal Investigator
  
  NIKI Etsuo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  有機工業化学
- Research Institution
  The University of Tokyo
Design and Evaluation of Novel Selenium-Containing Antioxidant
- Principal Investigator
  
  NIKI Etsuo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  有機工業化学
- Research Institution
  University of Tokyo
リポ蛋白質の超分子構造と機能
- Principal Investigator
  
  二木鋭雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
食品に含まれる抗酸化物質の機能解析と新規生体防御物質の設計
- Principal Investigator
  
  二木鋭雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
フリーラジカルによる細胞の酸化的傷害とその防御機構に関する基礎的研究
- Principal Investigator
  
  NIKI Etsuo
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
食品に含まれる抗酸化物質の機能解析と新規生体防御物質の設計
- Principal Investigator
  
  二木鋭雄
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Development, Design and Evaluation of Novel Natural and Synthetic Antioxidants
- Principal Investigator
  
  NIKI Etsuo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  有機工業化学
- Research Institution
  University of Tokyo, Research Center for Advanced Science and Technology

All 2019 2018 2017 2016 2015 2014 2013 2005 2004

All Journal Article Presentation Book Patent

[Book] Vitamin E: Chemistry and Nutritional Benefits2019
- Author(s)
  Noriko Noguchi
- Total Pages
  269
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-16K00882
[Book] レドックス疾患学2018
- Author(s)
  斎藤芳郎、野口範子、御簾博文、篁俊成
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16K00882
[Book] 別冊「医学のあゆみ」レドックスUPDATE ストレス制御の臨床医学・健康科学2015
- Author(s)
  斎藤芳郎、野口範子
- Total Pages
  360
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-25670084
[Book] パーキンソン病と酸化ストレス　酸化ストレスの医学、第2版2014
- Author(s)
  斎藤芳郎、野口範子
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25670084
[Journal Article] Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation.2018
- Author(s)
  Yuki Kimura, Minori Asa, Yasuomi Urano, Yoshiro Saito, Kiyotaka Nishikawa, Noriko Noguchi
- Journal Title
  
  Biochimie
  
  Volume: 153 Pages: 203-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00882
[Journal Article] Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle.2017
- Author(s)
  H Misu, H Takayama, Y Saito, Y Mita, A Kikuchi, K Ishii, K Chikamoto, T Kanamori, N Tajima, F Lan, Y Takeshita, M Honda, M Tanaka, S Kato, N Matsuyama, Y Yoshioka, Iwayama K, Tokuyama K, Akazawa N, Maeda S, Takekoshi K, Matsugo S, Noguchi N, S Kaneko, T Takamura.
- Journal Title
  
  Nature Med
  
  Volume: 23 Issue: 4 Pages: 508-516
- DOI
  10.1038/nm.4295
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26461328, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-17H04199
[Journal Article] Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47phox.2017
- Author(s)
  Bharatwaj Sowrirajan, Yoshiro Saito, Deepak Poudyal, Qian Chen, Hongyan Sui, Suk See DeRavin, Hiromi Imamichi, Toyotaka Sato, Douglas B. Kuhns, Noriko Noguchi, Harry L. Malech, H. Clifford Lane and Tomozumi Imamichi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 43441-43441
- DOI
  10.1038/srep43441
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-17K15688
[Journal Article] Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis.2017
- Author(s)
  Takaya Nakazawa, Yuta Miyanoki, Yasuomi Urano, Madoka Uehara, Yoshiro Saito, Noriko Noguchi
- Journal Title
  
  J. Steroid Biochem. Mol. Biol.
  
  Volume: 169 Pages: 69-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00882
[Journal Article] Oxidized Lipoprotein as a Major Vessel Cell Proliferator in Oxidized Human Serum.2016
- Author(s)
  Yoshiro Saito, and Noriko Noguchi
- Journal Title
  
  PLoS ONE
  
  Volume: 11 Issue: 8 Pages: e0160530-e0160530
- DOI
  10.1371/journal.pone.0160530
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25292078
[Journal Article] Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients.2016
- Author(s)
  Y. Saito, Y. Akazawa-Ogawa, A. Matsumura, K. Saigoh, S. Itoh, K. Sutou, M. Kobayashi, Y. Mita, M. Shichiri, S. Hisahara, Y. Hara, H. Fujimura, H. Takamatsu, Y. Hagihara, Y. Yoshida, T. Hamakubo, S. Kusunoki, S. Shimohama, N. Noguchi
- Journal Title
  
  Sci Rep
  
  Volume: 29 Issue: 1 Pages: 30793-30793
- DOI
  10.1038/srep30793
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-16K18707, KAKENHI-PROJECT-25292078
[Journal Article] New aspects of 24S-hydroxycholesterol in modulating neuronal cell death.2015
- Author(s)
  Noriko Noguchi, Yasuomi Urano, Wakako Takabe, Yoshiro Saito
- Journal Title
  
  Free Radical Biology & Medicine
  
  Volume: 87 Pages: 366-72
- DOI
  10.1016/j.freeradbiomed.2015.06.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670084, KAKENHI-PROJECT-26850089
[Journal Article] 24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8.2015
- Author(s)
  Vo DK, Urano Y, Takabe W, Saito Y, Noguchi N.
- Journal Title
  
  Steroids
  
  Volume: 印刷中 Pages: 230-237
- DOI
  10.1016/j.steroids.2015.02.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25830041, KAKENHI-PROJECT-25670084, KAKENHI-PROJECT-26850089
[Journal Article] The protective role of DJ-1 in ultraviolet-induced damage of human skin: DJ-1 levels in the stratum corneum as an indicator of antioxidative defense.2015
- Author(s)
  Shioji Ishiwatari, Minako Takahashi, Chie Yasuda, Maho Nakagawa, Tatsuya Kon, Yoshiro Saito, Noriko Noguchi, and Shoko Matsukuma
- Journal Title
  
  Archives of Dermatological Research
  
  Volume: 307 Issue: 10 Pages: 925-935
- DOI
  10.1007/s00403-015-1605-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670084, KAKENHI-PROJECT-25292078
[Journal Article] 7-Hydroxycholestrol as a possible biomarker of cellular lipid peroxidation: Difference between cellular and plasma lipid peroxidation.2014
- Author(s)
  Yoshiro Saito and Noriko Noguchi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25292078
[Journal Article] Diverse functions of 24(S)-hydroxycholesterol in the brain.2014
- Author(s)
  Noriko Noguchi, Yoshiro Saito, and Yasuomi Urano
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 446 Issue: 3 Pages: 692-696
- DOI
  10.1016/j.bbrc.2014.02.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-25830041
[Journal Article] Immunostaining of oxidized DJ-1 in human and mouse brains.2014
- Author(s)
  Saito, Y., T. Miyasaka, H. Hatsuta, K. Takahashi-Niki, K. Hayashi, Y. Mita, O. Kusano-Arai, H. Iwanari, H. Ariga, T. Hamakubo, Y. Yoshida, E. Niki, S. Murayama, Y. Ihara and N. Noguchi
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 73 Issue: 7 Pages: 714-728
- DOI
  10.1097/nen.0000000000000087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24790773, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25670084
[Journal Article] Induction of apoptosis and necroptosis by 24 (S)-hydroxycholesterol is dependent on activity of acyl-CoA : cholesterol acyltransferase1.2014
- Author(s)
  K Yamanaka, Y Urano, W Takebe, Y Saito, N Noguchi
- Journal Title
  
  Cell Death and Disease
  
  Volume: Vol. 5 Issue: 1 Pages: e990-e990
- DOI
  10.1038/cddis.2013.524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J03567, KAKENHI-PROJECT-25670084, KAKENHI-PROJECT-25830041
[Journal Article] Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death.2014
- Author(s)
  Akishi Okabe, Yasuomi Urano, Sayoko Itoh, Naoto Suda, Rina Kotani, Yuki Nishimura, Yoshiro Saito, and Noriko Noguchi
- Journal Title
  
  Redox Biology
  
  Volume: 2 Pages: 28-35
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670084
[Journal Article] The significance of oxidized DJ-1 protein (oxDJ-1) as a biomarker for Parkinson’s disease.2014
- Author(s)
  Ikuko Ogawa, Yoshiro Saito, Kazumasa Saigoh, Yoshie Hosoi, Yoshiyuki Mitsui, Noriko Noguchi, and Susumu Kusunoki
- Journal Title
  
  Brain and Nerve
  
  Volume: 66 Pages: 471-477
- NAID
  40020069623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670084
[Journal Article] Expression of the LXR{alpha} Protein in Human Atherosclerotic Lesions.2005
- Author(s)
  Watanabe Y., Jiang S, Takabe W, Ohashi R, Tanaka T, Uchiyama Y, Katsumi K, Iwanari H, Noguchi N, Naito M, Hamakubo T, Kodama T.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 25(3)
  
  Pages: 622-627
- Data Source
  KAKENHI-PROJECT-15209026
[Journal Article] Expression of the LXR{alpha} Protein in Human Atherosclerotic Lesions.2005
- Author(s)
  Watanabe Y, Jiang S, Takabe W, Ohashi R, Tanaka T, Uchiyama Y, Katsumi K, Iwanari H, Noguchi N, Naito M, Hamakubo T, Kodama T.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 25(3)
  
  Pages: 622-627
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209026
[Journal Article] Expression of the LXR{alpha} Protein in Human Atherosclerotic Lesions.2005
- Author(s)
  Watanabe Y, Jiang S, Takabe W, Ohashi R, Tanaka T, Uchiyama Y, Katsumi K, Iwanari H, Noguchi N, Naito M, Hamakubo T, Kodama T.
- Journal Title
  
  Arterioscler Thromb Vase Biol 25(3)
  
  Pages: 622-627
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209026
[Journal Article] Interaction between Hex and GATA transcription factors in vascular endothelial cells Inhibits flk-1/KDR-mediated VEGF signaling.2004
- Author(s)
  Minami T, Murakami T, Horiuchi K, Miura M, Noguchi T, Miyazaki JI, Hamakubo T, Aird WC, Kodama T.
- Journal Title
  
  J Biol Chem. 279(20)
  
  Pages: 20626-20635
- Data Source
  KAKENHI-PROJECT-15209026
[Journal Article] Effect on cell gene expression by shear stress, oxygen concentration, low-density lipoprotein as studied by a novel flow cell culture system.2004
- Author(s)
  Warabi E, Wada Y, Kajiwara H, Kobayashi M, Koshiba N, Hisada T, Shibata M, Ando J, Tsuchiya M, Kodama T, Noguchi N.
- Journal Title
  
  Free Radic Biol Med. 1;37(5)
  
  Pages: 682-692
- Data Source
  KAKENHI-PROJECT-15209026
[Journal Article] Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system2004
- Author(s)
  Warabi E, Wada Y, Kajiwara H, Kobayashi M, Koshiba N, Hisada T, Shibata M, Ando J, Tsuchiya M, Kodama T, Noguchi N.
- Journal Title
  
  Free Radic Biol Med. Sep 1;37(5)
  
  Pages: 682-694
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209026
[Journal Article] Interaction between Hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated VEGF signaling.2004
- Author(s)
  Minami T, Murakami T, Horiuchi K, Miura M, Noguchi T, Miyazaki JI, Hamakubo T, Aird WC, Kodama T.
- Journal Title
  
  J Biol Chem. 279(20)
  
  Pages: 20626-20635
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209026
[Journal Article] Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system.2004
- Author(s)
  Warabi E, Wada Y, Kajiwara H, Kobayashi M, Koshiba N, Hisada T, Shibata M, Ando J, Tsuchiya M, Kodama T, Noguchi N.
- Journal Title
  
  Free Radic Biol Med. 1;37(5)
  
  Pages: 682-694
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209026
[Patent] セレノプロテインPの発現抑制剤およびその利用2017
- Inventor(s)
  斎藤芳郎、三田雄一郎、野口範子、内田理沙、安原小百合、横大路将
- Industrial Property Rights Holder
  斎藤芳郎、三田雄一郎、野口範子、内田理沙、安原小百合、横大路将
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K00882
[Patent] DJー１タンパク質産生促進用組成物2017
- Inventor(s)
  斎藤芳郎、野口範子、安藤万由
- Industrial Property Rights Holder
  斎藤芳郎、野口範子、安藤万由
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K00882
[Patent] DJー１タンパク質産生促進用組成物2017
- Inventor(s)
  斎藤芳郎、野口範子、安藤万由
- Industrial Property Rights Holder
  斎藤芳郎、野口範子、安藤万由
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K00882
[Patent] 経鼻投与用医薬組成物2017
- Inventor(s)
  浦野泰臣、野口範子
- Industrial Property Rights Holder
  浦野泰臣、野口範子
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-16K00882
[Patent] ２型糖尿病の治療及び／又は予防薬2014
- Inventor(s)
  斎藤芳郎、吉岡佑弥、中山華穂、西藤有希奈、三田雄一郎、野口範子
- Industrial Property Rights Holder
  斎藤芳郎、吉岡佑弥、中山華穂、西藤有希奈、三田雄一郎、野口範子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-165695
- Filing Date
  2014-08-18
- Data Source
  KAKENHI-PROJECT-25292078
[Patent] ２型糖尿病の治療及び／又は予防薬2013
- Inventor(s)
  斎藤芳郎、吉岡佑弥、中山華穂、西藤有希奈、三田雄一郎、野口範子
- Industrial Property Rights Holder
  斎藤芳郎、吉岡佑弥、中山華穂、西藤有希奈、三田雄一郎、野口範子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-175612
- Filing Date
  2013-08-27
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] 脂質が誘導する小胞体ストレスとビタミンE2019
- Author(s)
  木村勇輝、浦野泰臣、斎藤芳郎、野口範子
- Organizer
  第30回ビタミンＥ研究会
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] 膵β細胞モデルMIN6におけるセレン代謝とビタミンEの添加効果2018
- Author(s)
  斎藤芳郎、中尾昌平、稲荷尚吾、三田雄一郎、野口範子
- Organizer
  第２９回ビタミンE研究会
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] ER stress plays important roles in 24S-hydroxycholesterol-induced neuronal cell death2018
- Author(s)
  Noguchi N, Urano Y, Vo Ho D-K, Araki H, and Kimura Y
- Organizer
  7th ENOR SYMPOSIUM, Oxysterols and sterol derivatives in health and disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] 脳特異的オキシステロール24S-hydroxycholesterolによる神経細胞死誘導における小胞体の関与2018
- Author(s)
  浦野泰臣、野口範子
- Organizer
  第27回日本Cell death学会学術集会
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] Curcumin誘導体GT863のAβ産生抑制機構の解明2018
- Author(s)
  高八美菜、浦野泰臣、杉本八郎、野口範子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] 24S-Hydroxycholesterol誘導性細胞死に対するビタミンEの効果2018
- Author(s)
  木村勇輝、浦野泰臣、西川喜代孝、野口範子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] 24S-ヒドロキシコレステロールが誘導する神経細胞死に対するビタミンEの抑制機構の解析2018
- Author(s)
  木村　勇輝、浦野泰臣、野口範子
- Organizer
  第２９回ビタミンE研究会
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] 24S-ヒドロキシコレステロールが誘導する神経細胞死に対するビタミンE同族体の抑制作用のちがい2017
- Author(s)
  木村勇輝、宮軒勇太、浦野泰臣、野口範子
- Organizer
  第２８回　ビタミンE研究会
- Place of Presentation
  東洋大学白山キャンパス（東京都文京区
- Year and Date
  2017-02-20
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] Regulation of cell signaling by lipid oxidation products and antioxidants2017
- Author(s)
  野口範子
- Organizer
  Gordon Research Conference-Oxidative Stress & Diseases
- Place of Presentation
  ルッカ（イタリア）
- Year and Date
  2017-03-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00882
[Presentation] 内在性long non-coding RNAによる新規Selenoprotein P翻訳制御メカニズム2016
- Author(s)
  三田雄一郎、斎藤芳郎、内田理沙、安原小百合、野口範子
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] セレノプロテインPの阻害抗体による糖尿病治療効果の解析―インスリン抵抗性および分泌能を改善する抗体医薬の開発2016
- Author(s)
  三田雄一郎、中山華穂、稲荷尚吾、西藤有希奈、吉岡佑弥、曽谷奏、高部稚子、御簾博文、篁俊成、高橋和彦、野口範子、斎藤芳郎
- Organizer
  日本糖尿病学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] Selenoprotein P-neutralizing antibody ameliorates glucose intolerance and insulin resistance, insulin secretion2016
- Author(s)
  Shogo Inari, Yuichiro Mita, Kaho Nakayama, Wakako Takabe, Noriko Noguchi, and Yoshiro Saito
- Organizer
  SFRBM’s 23th Annual Meeting
- Place of Presentation
  San Francisco (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] セレノプロテインＰによる膵β細胞死に対するビタミンＥの効果2016
- Author(s)
  斎藤芳郎、稲荷尚吾、三田雄一郎、高部稚子、御簾博文、篁俊成、野口範子
- Organizer
  第27回ビタミンＥ研究会
- Place of Presentation
  アルファあなぶきホール（高松）
- Year and Date
  2016-01-08
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] Jurkat細胞のSelenoprotein P取り込みに関与するApoER2の同定2016
- Author(s)
  堺菜穂子、三田雄一郎、吉岡佑弥、野口範子、斎藤芳郎
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] 糖尿病関連タンパク質selenoprotein Pの翻訳を抑制する内在性long non-coding RNAの作用2016
- Author(s)
  内田理沙、三田雄一郎、安原小百合、斎藤芳郎、野口範子
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] 膵β細胞モデルMIN6がセレノプロテインPを産生する意義2016
- Author(s)
  中尾昌平、三田雄一郎、野口範子、斎藤芳郎
- Organizer
  日本生化学会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] Selenoprotein Pの中和抗体によるインスリン抵抗性及び分泌能の改善2016
- Author(s)
  三田雄一郎、中山華穂、稲荷尚吾、西藤有希奈、吉岡佑弥、高部稚子、御簾博文、篁　俊成、野口範子、斎藤芳郎
- Organizer
  日本酸化ストレス学会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] セレン含有タンパク質が低下したSBP2変異患者におけるビタミンEの投与および投与中止に伴う変化2015
- Author(s)
  斎藤芳郎、七里元督、濱島崇、萩原義之、吉田康一、野口範子
- Organizer
  第26回ビタミンＥ研究会
- Place of Presentation
  東京
- Year and Date
  2015-01-10
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] Distribution of oxidized DJ-1 in human and mouse brain - Effects of aging process2015
- Author(s)
  Yoshiro SAITO, Yuichiro MITA, Kojiro HAYASHI, Takuma KASHI, Yuto KATAOKA, Asa IWASAKI, and Noriko NOGUCHI
- Organizer
  SFRBM 2015: SFRBM's 22nd Annual Meeting
- Place of Presentation
  Westin Boston Waterfront （ボストン）
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] 血漿セレン含有タンパク質セレノプロテインＰを標的とした２型糖尿病の抗体医薬の開発2015
- Author(s)
  斎藤芳郎、中山華穂、三田雄一郎、野口範子
- Organizer
  第67回日本ビタミン学会
- Place of Presentation
  奈良県新公会堂（奈良）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] セレノプロテインPの発現・分泌に与える過酸化水素および抗酸化物質の影響2015
- Author(s)
  三田雄一郎、斎藤芳郎、野口範子
- Organizer
  第26回ビタミンＥ研究会
- Place of Presentation
  東京
- Year and Date
  2015-01-09
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] SBP2変異によるセレン含有タンパク質欠乏患者におけるコレステロールの酸化―細胞膜と血漿リポタンパク質の酸化反応の違い2015
- Author(s)
  斎藤芳郎、七里元督、濱島　崇、萩原義久、吉田康一、野口範子
- Organizer
  第57回　日本脂質生化学会
- Place of Presentation
  一橋大学一橋講堂（東京）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] パーキンソン病モデルマウス脳内における酸化DJ-1の分布2015
- Author(s)
  橿　拓磨、片岡佑斗、林宏次朗、三田雄一郎、斎藤芳郎、野口範子
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学大会・合同大会（BMB2015）
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] 膵臓β細胞モデルMIN6は過剰なSelenoprotein Pにより障害を受ける2015
- Author(s)
  稲荷尚吾、高部稚子、三田雄一郎、御簾博文、篁俊成、野口範子、斎藤芳郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学大会・合同大会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] 各臓器における酸化DJ-1の分布と加齢に伴う変化2015
- Author(s)
  三田雄一郎、岩崎安紗、橿　拓磨、片岡佑斗、斎藤芳郎、野口範子
- Organizer
  第68回日本酸化ストレス学会
- Place of Presentation
  かごしま県民交流センター（鹿児島）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] 血漿セレノプロテインＰによるセレン代謝制御と2型糖尿病2014
- Author(s)
  斎藤芳郎、吉岡佑弥、三田雄一郎、御簾博文、田中睦、篁俊成、野口範子
- Organizer
  第25回日本微量元素学会
- Place of Presentation
  岡山
- Year and Date
  2014-07-03
- Invited
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] Immunostaining of oxidized DJ-1 in human and mouse brain.2014
- Author(s)
  Yoshiro SAITO, Tomohiro MIYASAKA, Hiroyuki HATSUTA, Kazuko TAKAHASHI-NIKI, Hiroyoshi ARIGA, Shigeo MURAYAMA, Yasuo IHARA, Noriko NOGUCHI.
- Organizer
  Neuroscience 2014
- Place of Presentation
  ワシントンDC
- Year and Date
  2014-11-17
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] パーキンソン病関連タンパク質DJ-1の酸化による高分子化に関する研究2014
- Author(s)
  小林茉佑香、斎藤芳郎、菊地愛、村松香奈、野口範子
- Organizer
  第67回日本酸化ストレス学会
- Place of Presentation
  京都
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] SBP2変異によるセレン含有蛋白質に対するビタミンEの効果―投与および投与中止に伴う脂質酸化物の変化2014
- Author(s)
  斎藤芳郎、七里元督、濱島崇、萩原義之、吉田康一、野口範子
- Organizer
  第17回Vitamin E Update Forum
- Place of Presentation
  東京
- Year and Date
  2014-08-06
- Invited
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] 酸化DJ-1特異的抗体を用いたマウスおよびヒト脳切片の免疫染色2014
- Author(s)
  斎藤芳郎、宮坂知宏、初田裕幸、仁木加寿子、有賀寛芳、村山繁雄、井原康夫、野口範子
- Organizer
  第37回日本神経科学会Neuroscience 2014
- Place of Presentation
  京都
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] 糖尿病関連タンパク質Selenoprotein Pの発現制御機構の解析2014
- Author(s)
  三田雄一郎、斎藤芳郎、野口範子
- Organizer
  第67回日本酸化ストレス学会
- Place of Presentation
  京都
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] パーキンソン病関連分子DJ-1の細胞外分泌に及ぼすビタミンEの効果2014
- Author(s)
  斎藤芳郎、山本貴之、浦野泰臣、野口範子
- Organizer
  第25回ビタミンE研究会
- Place of Presentation
  米子
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] 血中の酸化型DJ-1異常高値の臨床的意義2014
- Author(s)
  西郷和真、斎藤芳郎、小川郁子、細井幸恵、三井良之、花田一志、上田昌美、石井一成、野口範子、楠進
- Organizer
  第67回日本酸化ストレス学会
- Place of Presentation
  京都
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] セレノプロテインＰは分解経路・非分解経路を介して細胞内へセレンを供給する2014
- Author(s)
  吉岡佑弥、三田雄一郎、西藤有希奈、野口範子、斎藤芳郎
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] PDの診断マーカーである血中oxDJ-1の異常高値を示したDLBの4例2014
- Author(s)
  西郷和真、斎藤芳郎、小川郁子、細井幸恵、三井良之、花田一志、上田昌美、石井一成、野口範子、楠進
- Organizer
  第33回日本認知症学会
- Place of Presentation
  横浜
- Year and Date
  2014-12-01
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] パーキンソン病モデルマウス脳内におけるDJ-1の酸化2014
- Author(s)
  橿拓磨、斎藤芳郎、林宏次朗、三田雄一郎、片岡佑斗、野口範子
- Organizer
  第67回日本酸化ストレス学会
- Place of Presentation
  京都
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] Study of selenium supply mechanism of selenoprotein P using 75Se and immunological methods2013
- Author(s)
  Yoshiro Saito, Yuuya Yoshioka, Yuichiro Mita, Kaho Nakayama, Yukina Nishito, Kazuhiko Takahashi, Noriko Noguchi
- Organizer
  10th International Symposium on Selenium in Biology and Medicine
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] セレン欠乏に伴う酸化ストレス障害に対するビタミンEの効果-SBP2遺伝子異常に対する治療への応用2013
- Author(s)
  斎藤芳郎、七里元督、濱島　崇、萩原義久、吉田康一、野口範子
- Organizer
  第65回ビタミン学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] 7-hydroxycholestrol as a possible biomarker of cellular lipid peroxidation- difference between cellular and plasma lipid peroxidation2013
- Author(s)
  Yoshiro Saito, Noriko Noguchi
- Organizer
  3rd ENOR Symposium Oxysterols: Markers and Pathways
- Place of Presentation
  Swansea, UK
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] パーキンソン病関連分子DJ-1の酸化に伴う高分子化およびシステインの役割に関する研究2013
- Author(s)
  小林茉佑香、村松香奈、斎藤芳郎、野口範子
- Organizer
  第66回日本酸化ストレス学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] Oxidation of DJ-1 in the brain of Parkinson disease patients-possible biomarker for diagnosis of Parkinson disease at early stage2013
- Author(s)
  Yoshiro Saito, Tomohiro Miyasaka, Takao Hamakubo, Etsuo Niki, and Noriko Noguchi
- Organizer
  Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] 細胞内および脳内における酸化DJ-1の分布に関する研究2013
- Author(s)
  林宏次朗、斎藤芳郎、宮坂知宏、仁木加寿子、有賀寛芳、野口範子
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25670084
[Presentation] SBP2遺伝子異常に伴う酸化ストレスに対するビタミンEの効果- コレステロール酸化物による脂質酸化の評価2013
- Author(s)
  斎藤芳郎、七里元督、濱島　崇、萩原義久、吉田康一、野口範子
- Organizer
  第16回Vitamin E Update Forum
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25292078
[Presentation] 75Seおよび免疫学的手法を用いたセレノプロテインＰのセレン運搬機構の解析2013
- Author(s)
  吉岡佑弥、西藤有希奈、三田雄一郎、高橋和彦、野口範子、斎藤芳郎
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25292078

1. NIKI Etsuo (20011033)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. YAMAMOTO Yorihiro (60134475)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. Yoshiro Saito (70357060)

# of Collaborated Projects: 4 results

# of Collaborated Products: 50 results
4. TAKAHASHI Mareyuki (60280955)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 保田浩 (10220154)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 浦野泰臣 (00546674)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
7. Fujimoto Tetsushi (50278313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KODAMA Tatsuhiko (90170266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. NAITO Makoto (30045786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. DOI Takefumi (00211409)

# of Collaborated Projects: 1 results

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11. MINAMI Takashi (00345141)

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12. SAIGOH Kazumasa (50319688)

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13. TAKAHASHI Kazuhiko (10113581)

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14. 篠原さやか (90618224)

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15. 川口章 (50257903)

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17. 三枝麻由美 (10359664)

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18. 朝井友紀子 (10588172)

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19. 中田喜文 (50207809)

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20. 三田雄一郎 (70609122)

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21. TAKAMURA Toshinari

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23. 御簾博文

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24. 竹下有美枝

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25. 金子周一

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27. 齊藤祐子

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28. 高橋良輔

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29. 久保義弘

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30. 吉田明

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31. 村山繁雄

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33. 高橋淑子

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35. 浜窪隆雄

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Noguchi Noriko 野口 範子

NOGUCHI Noriko 野口 範子

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The mechanism of the regulation for optimized protective effect of exercise against diabetes mellitusPrincipal Investigator

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Mechanism of inhibition of oxysterol-induced Alzheimer's disease by vitamin EPrincipal Investigator

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Evaluation of antioxidant activity against atherosclerosis using co-culture systemPrincipal Investigator

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[Book] Vitamin E: Chemistry and Nutritional Benefits2019

Noguchi Noriko 野口範子

NOGUCHI Noriko 野口範子

[Book] 別冊「医学のあゆみ」レドックスUPDATE ストレス制御の臨床医学・健康科学2015

[Book] パーキンソン病と酸化ストレス　酸化ストレスの医学、第2版2014