yachie akihiro 谷内江昭宏

… Alternative Names

YACHIE Akihiro 谷内江昭宏

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Researcher Number	40210281
Other IDs
External Links
Affiliation (Current)	2024: 金沢大学, その他部局等, その他
Affiliation (based on the past Project Information) *help	2024: 金沢大学, その他部局等, その他 2019 – 2023: 金沢大学, 附属病院, 特任教授 2008 – 2019: Kanazawa University, 医学系, 教授 2005 – 2007: Kanazawa University, Graduate School of Medical Science, Professor, 医学系研究科, 教授 2002 – 2004: Kanazawa University, Faculty of Medicine, Professor, 医学部, 教授 … More 2001: 金沢大学, 医学部・保健学科, 教授 2001: 金沢大学, 医学部保健学科, 教授 1997 – 1999: 金沢大学, 医学部, 教授 1996: KANAZAWA UNIVERSITY,SCHOOL OF MEDCINE ASSOCIATE PROFESSOR, 医学部, 助教授 1995: 金沢大学, 医学部, 講師 1995: 金沢大学, 医学部・附属病院, 助手 1994 – 1995: 金沢大学, 医学部附属病院, 助手 1993: KANAZAWA UNIV., DEPT.PEDIATRICS, ASSISTANT PROFESSOR, 医学部・附属病院, 助手 1992: 金沢大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Laboratory medicine / Pediatrics / Pediatrics / Eating habits / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 52010:General internal medicine-related / Hygiene and public health … More / Sports science / Hematology / Hematology / Embryonic/Neonatal medicine Less
Keywords	Principal Investigator サイトカイン / IgE / アレルギー / 新生児 / ヘモクロマトーシス / アロ抗原 / inflammation / monocyte / 炎症 / 単球 … More / HIGH AFFINITY IGE RECEPTOR / BASOPHIL / 高親和性IgE受容体 / 好塩基球 / CD11b / CD69 / フローサイトメトリー / 胎児治療 / アロ抗体 / 妊娠 / 胎児肝 / 新生児ヘモクロマトーシス / 先制医療 / angiopoietin / 若年性特発性関節炎 / 膠原病 / 小児免疫 / オミクス情報 / cytokine profile / iPS / sTNF-Rs / iPS 細胞 / オミクス / バイオマーカー / NK 細胞 / IL-18 / biomarker / MAS / sJIA / cytokine / cell injury / oxidized LDL / heme oxygenase / HO-1 / 細胞傷害 / 酸化LDL / ヘムオキシゲナーゼ / anti-inflammatory therapy / oxidative stress / heme oxygenase-1 / インフルエンザ:influenza / 川崎病:MCLS / 炎症:inflammation / ヘムオキシゲナーゼ1:HO-1 / 単球:monocyte / 抗炎症治療 / 酸化ストレス / ヘムオキシゲナーゼ1 / FLOW CYTOMETRY / ウイルス感染 / 乳幼児 / ALLERGY / SURFACE IGE / NEONATE / 乳児 / F_<cε>RI / 表面IgE / Superantigens / Cytokines / Eosinophil / アレルギー疾患 / 全血法 / フロー・サイトメトリー / 表面抗原 / TCRVβ / スーパー抗原 / 好酸球 / Epstein-Barr virus(EBV) / Flowcytometry / Epstein-Barr virus (EBV) / CD5 / EBV-HLH / CAEBV / EBウイルス / 免疫寛容機構 / T細胞抗原受容体解析 / 第二変異 / 重症複合免疫不全症 / Omenn症候群 … More Except Principal Investigator ヘムオキシゲナーゼ / 血管内皮細胞 / 血管炎 / HO-1 / トロンボモジュリン / 組織因子 / 腎尿細管 / 炎症 / ヘムオキシゲナーゼ-1 / 移植片対宿主病 / 一塩基置換 / 造血幹細胞移植 / TNF-α / CD244 / TREC / 血管内皮障害 / in situ hybridization / EBER-1 / EBV terminal repeat / PCR method / 細胞傷害性T細胞 / 再生不良性貧血 / 食品 / 嗜好食品 / 家族性地中海熱 / 自己炎症疾患 / 酸化ストレス / 血栓形成 / リポポリサッカライド / PAI-1 / ヘムオキシゲナーゼ1 / 血栓 / 遺伝病 / ストレス防御 / 肺高血圧症 / Aluくり返し配列 / 単球 / 癌転移 / 幹細胞 / 免疫寛容 / laeverin / 胚シグナル / 血液凝固異常 / 遺伝子一塩基多型 / 移植片対宿主病(GVHD) / ADAMTS13 / 5年全生存率 / 自然免疫 / 3年全生存率 / 造血幹細胞移植後転帰 / UNC-93 homolog B1 / ADAMTS-13 / 一塩基多型（SNP) / 血栓性微小血管障害症 / 同種造血幹細胞移植 / 無細胞系 / 発症トリガー / 環境因子 / トルコ / インフラマソーム / イメージング / 認知機能 / 抗老化作用 / メチルキサンチン誘導体 / 環境 / ストレス / 低酸素 / 熱ストレス / 水 / 運動 / スタチン / サイトカイン / 相血幹細胞移植 / アンギオポエチン-1 / タクロリムス / 移植予後 / FCRL3 / 遺伝子組換えトロンボモジュリン / タクロリムス（ＦＫ506） / Fc receptor-like 3遺伝子 / ヘムオキシゲナーゼ-１(HO-1) / 移植後合併症 / endothelial cell / thrombomodulin / plasminogen activator inhibitor 1 / tissue factor / inflammation / thrombosis / Heme oxygenase-1 / ヘムオキシゲナーゼー1 / TFPI / cytotoxic T cell / autoantibody / paroxysmal nocturnal hemoglobinuria / moesin / DRS / aplastic anemia / 細胞障害性T細胞 / 自己抗体 / モエシン / 発作性夜間ヘモグロビン尿症 / DRS-1 / cytokine production / cytotoxic granules / CD8β chain / CDR3 spectratyping / immunologic ontogeny / メモリーT細胞 / 免疫発達 / サイトカイン産生 / 細胞傷害性顆粒 / CDR3領域アミノ酸配列 / CD8β鎖 / CDR3サイズ解析 / 小児発達免疫 / Alu-Alu recombination / Inflammation / Endothelial injury / Vasculitis / Proximal tubular epithelial cells / Monocytes / Oxidative stress / Heme oxygenase / 肺高血圧 / 先天性心疾患 / ECV304 / 造血系細胞 / Carbon monoxide / EB virus (EBV) / in situ hubridization / EVE terminal repeat / PCR法 / EBウイルス(EBV) / EB virus(EBV) / cytotoxic T cells / HCA-DR / T-cell receptor / T-cell clone / aplastic onemia / シクロスポリン / HLA-DRB1 / HLA-DR / T細胞レセプター / T細胞クローン / 生理学 / 栄養学 / 認知予防 / 老化予防 / がん化予防 / 栄養 / ヘムオキシゲナーゼ１欠損症、インド / ビリルビン代謝 / 溶血性貧血 / ヘムオキシゲナーゼ１欠損症 / G304R変異 / 家族性地中海熱(FMF) / 炎症制御 / pyrin蛋白 / MEFV遺伝子 / heme oxygenase / 非侵襲的 / モニタリング / バイオピリン / 新生児 / ビリルビン / 一酸化炭素 / NF-κB / 一酸化炭素(CO) / クルクミン / 一酸化炭 / プラスミノゲンアクチベーター・インヒビター / GVHD / 乳児白血病 / 骨髄移植 / ヘモグロビン / 内皮細胞 / 凝固・線溶 / 血管新生 / がん転移 / 川崎病 / 感染症 / マクロファージ Less

新生児ヘモクロマトーシスの原因となるアロ抗体同定とIVIG治療の理論的基盤の確立Principal Investigator
- Principal Investigator
  
  谷内江昭宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanazawa University
新規胚シグナルlaeverinの幹細胞と免疫システムに対する作用の解明と臨床応用
- Principal Investigator
  
  藤原浩
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
Identification of allo-specific antibody responsible for the pathogenesis of neonatal hemochromatosisPrincipal Investigator
- Principal Investigator
  
  YACHIE AKIHIRO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanazawa University
Effect of heme oxygenase-1 on treatment results after hematopoietic stem cell transplantation and new therapeutic strategies
- Principal Investigator
  
  Morishita Eriko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kanazawa University
Theobromine, a primary methylxanthine in cacao beans, improves cognitive performance.
- Principal Investigator
  
  SUGIMOTO Naotoshi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa University
Comparative survey of endogenous and environmental factors that activate autoinflammatory disease responsible gene products in Turkey and Japan
- Principal Investigator
  
  MASUMOTO JUNYA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  Ehime University
The effect of exercise on water absorption
- Principal Investigator
  
  SUGIMOTO Naotoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Sports science
- Research Institution
  Kanazawa University
The impact of hemoxygenase-1 (HO-1) on the treatment outocome after bone marrow transplantation and the possibility of HO-1 as a new therapeutic target
- Principal Investigator
  
  MORISHITA Eriko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kanazawa University
Omics-based analysis of molecular pathogenesis of systemic juvenile idiopathic arthritis and development of novel therapeutic interventionPrincipal Investigator
- Principal Investigator
  
  Yachie Akihiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
The roles of methylxanthine derivative on prevention of several disorders
- Principal Investigator
  
  SUGIMOTO Naotoshi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa University
The discovery of the second case of human heme oxygenase-1 deficiency: biological evidence of HO-1 enzyme
- Principal Investigator
  
  KOIZUMI SHOICHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Evaluation of immune-regulatory functions in auto-inflammatory illnesses
- Principal Investigator
  
  TOMA Tomoko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Investigation of antithrombotic effects of heme oxygenase-1 on the hypercoagulable state by inflammation or oxidative stress
- Principal Investigator
  
  MORISHITA Eriko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kanazawa University
Establishment of novel diagnostic parameters for the early therapeutic intervention of EBV-associated lymphoproliferative diseases.Principal Investigator
- Principal Investigator
  
  YACHIE Akihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Baby-friendly perinatal care with non-invasive monitoring of neonatal stress
- Principal Investigator
  
  NAGAOKI Syuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kanazawa University
Physiological importance of heme oxygenase-1 on hemopoiesis, inflammation and immunology system
- Principal Investigator
  
  KOIZUMI Shoichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Molecular mechanisms underlying the complex clinical features of combined immunodeficiency disordersPrincipal Investigator
- Principal Investigator
  
  YACHIE Akihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
The effects of Heme Oxygenase-1 on expression of blood coagulation/fibrinolysis associated proteins.
- Principal Investigator
  
  SEKIYA Akiko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kanazawa University
Protection mechanism of thrombotic formation though heme oxygenase-1 in stress response
- Principal Investigator
  
  MORISHITA Eriko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kanazawa University
Analysis of mechanisms responsible for clonal expansion of PNH-type hematopoietic stem cells mediated by autoreactive T cells in patients with bone marrow failure
- Principal Investigator
  
  NAKAO Shinji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Development of novel anti-inflammatory therapy through regulation of heme oxygenase-1 production by monocytesPrincipal Investigator
- Principal Investigator
  
  YACHIE Akihiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Research on regulatory mechanism of inflammation by HO-1 and development of novel anti-inflammatory threrapyPrincipal Investigator
- Principal Investigator
  
  YACHIE Akihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  KANAZAWA UNIVERSITY
Molecular Analysis of Immunological Reconstitution after Hematopoietic Stem Cell Transplantation in Childhood
- Principal Investigator
  
  UEHARA Takahiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  KANAZAWA UNIVERSITY
マクロファージの活性化とヘムオキシゲナーゼ1発現:癌細胞における血管新生との相関
- Principal Investigator
  
  KOIZUMI Shoichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Multilateral-physiological and functional evidences of the heme oxygenase-1 (HO-1) enzyme : learning from the first case with human HO-1deficiency
- Principal Investigator
  
  KOIZUMI Shoichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Pathogenesis of Diverse Clinical Manifestations of EBV-Related Disorders : Mechanisms of Target-Cell Specific Infection, Regulation of Viral Gene Expression and Clonal Expansion.
- Principal Investigator
  
  OHTA Kazuhide
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
MECHANISM OF ALLERGIC SENSITIZATION DURING INFANCYPrincipal Investigator
- Principal Investigator
  
  YACHIE Akihiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  KANAZAWA UNIVERSITY
IGE BINDING AND CD38 EXPRESSION ON BASOPHIL SURFACE DURING INFANCY AND THEIR FUNCTIONAL RELEVANCEPrincipal Investigator
- Principal Investigator
  
  YACHIE Akihiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  KANAZAWA UNIVERSITY
Isolation of T-cell clones cytotoxic agcirst nemotopoietic progenitor cells from a patienl with aplastic aremia
- Principal Investigator
  
  NAKAO Shinji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Flowcytometric Analysis of Eosinophil Surface Antigens UtlizingPrincipal Investigator
- Principal Investigator
  
  YACHIE Akihiro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University

[Journal Article] Clinical perspectives and therapeutic strategies: pediatric autoinflammatory disease-a multi-faceted approach to fever of unknown origin of childhood2022
- Author(s)
  Yachie A.
- Journal Title
  
  Inflamm Regen.
  
  Volume: 42 Issue: 1 Pages: 21-21
- DOI
  10.1186/s41232-022-00204-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07933
[Journal Article] Pathogenic roles and diagnostic utility of interleukin-18 in autoinflammatory diseases2022
- Author(s)
  Shimizu M, Takei S, Mori M, Yachie A.
- Journal Title
  
  Front Immunol.
  
  Volume: 13 Pages: 951535-951535
- DOI
  10.3389/fimmu.2022.951535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07933
[Journal Article] A randomised, double-blind, placebo-controlled phase III trial on the efficacy and safety of tocilizumab in patients with familial Mediterranean fever2022
- Author(s)
  Koga T, Sato S, Hagimori N, Yamamoto H, Ishimura M, Yasumi T, Kirino Y, Ikeda K, Yachie A, Migita K, Kishida D, Atsumi T, Kawakami A.
- Journal Title
  
  Clin Exp Rheumatol.
  
  Volume: 40 Pages: 1535-1542
- DOI
  10.55563/clinexprheumatol/fgx9vv
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07933
[Journal Article] Heme Oxygenase-1 Deficiency and Oxidative Stress: A Review of 9 Independent Human Cases and Animal Models2021
- Author(s)
  Yachie A
- Journal Title
  
  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
  
  Volume: 22 Issue: 4 Pages: 1514-1514
- DOI
  10.3390/ijms22041514
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08339
[Journal Article] Role of E148Q in familial Mediterranean fever with an exon 10 mutation in MEFV.2021
- Author(s)
  Miyashita K, Matsuda Y, Okajima M, Toma T, Yachie A, Wada T.
- Journal Title
  
  Pediatr Int
  
  Volume: 64 Issue: 1 Pages: 214-219
- DOI
  10.1111/ped.14696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08226, KAKENHI-PROJECT-22K07933
[Journal Article] Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells2021
- Author(s)
  Sugimoto Naotoshi、Katakura Masanori、Matsuzaki Kentaro、Miyamoto Mayumi、Sumiyoshi Eri、Wada Taizo、Yachie Akihiro、Nakamura Hiroyuki、Shido Osamu
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 23 Issue: 4 Pages: 1-8
- DOI
  10.3892/mmr.2021.11889
- NAID
  120007165535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01963, KAKENHI-PROJECT-20K20309, KAKENHI-PROJECT-19K22751, KAKENHI-PROJECT-19H03882, KAKENHI-PROJECT-18K06853
[Journal Article] Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis during tocilizumab therapy.2020
- Author(s)
  Irabu H, Shimizu M, Kaneko S, Inoue N, Mizuta M, Nakagishi Y, Yachie A.
- Journal Title
  
  Pediatric Research
  
  Volume: in press Issue: 6 Pages: 934-939
- DOI
  10.1038/s41390-020-0843-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08339, KAKENHI-PROJECT-18K07786
[Journal Article] Serum Leucine-Rich α2-Glycoprotein as a Biomarker for Monitoring Disease Activity in Patients with Systemic Juvenile Idiopathic Arthritis.2019
- Author(s)
  Shimizu M, Inoue N, Mizuta M, Nakagishi Y, Yachie A.
- Journal Title
  
  J Immunol Res.
  
  Volume: 2019 Pages: 3140204-3140204
- DOI
  10.1155/2019/3140204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Corticosterone inhibits the expression of cannabinoid receptor?1 and cannabinoid receptor agonist?induced decrease in cell viability in glioblastoma cells2019
- Author(s)
  Sugimoto Naotoshi、Ishibashi Hiroaki、Ueda Yoshibumi、Nakamura Hiroyuki、Yachie Akihiro、Ohno?Shosaku Takako
- Journal Title
  
  Oncology Letters
  
  Volume: 18 Pages: 1557-1563
- DOI
  10.3892/ol.2019.10456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07685, KAKENHI-PROJECT-16H05513, KAKENHI-PROJECT-17H01963, KAKENHI-PROJECT-17K19341
[Journal Article] Macrophage activation syndrome in neonates born to mothers with adult-onset Still's disease: Perinatal effect of maternal IL-18.2019
- Author(s)
  Shimizu M, Kizawa T, Kato R, Suzuki T, Yachie A.
- Journal Title
  
  Clin Immunol
  
  Volume: 207 Pages: 36-39
- DOI
  10.1016/j.clim.2019.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07786, KAKENHI-PROJECT-19K08339
[Journal Article] Heat attenuates sensitivity of mammalian cells to capsaicin.2019
- Author(s)
  Sugimoto N, Matsuzaki K, Katakura M, Nakamura H, Ueda Y, Yachie A, Shido O.
- Journal Title
  
  J Biochem Mol Toxicol.
  
  Volume: e22288 Issue: 5 Pages: 1-7
- DOI
  10.1002/jbt.22288
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06853, KAKENHI-PROJECT-17H01963, KAKENHI-PROJECT-15KT0003, KAKENHI-PROJECT-19K07685, KAKENHI-PROJECT-17K19341
[Journal Article] Cytokine profile of macrophage activation syndrome associated with Kawasaki disease.2019
- Author(s)
  Jinkawa A, Shimizu M, Nishida K, Kaneko S, Usami M, Sakumura N, Irabu H, Takakuwa M, Inoue N, Mizuta M, Ikawa Y, Fujita S, Yachie A.
- Journal Title
  
  Cytokine.
  
  Volume: 119 Pages: 52-56
- DOI
  10.1016/j.cyto.2019.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873, KAKENHI-PROJECT-18K07786
[Journal Article] Clinical significance of serum CXCL9 levels as a biomarker for systemic juvenile idiopathic arthritis associated macrophage activation syndrome.2019
- Author(s)
  Mizuta M, Shimizu M, Inoue N, Nakagishi Y, Yachie A.
- Journal Title
  
  Cytokine
  
  Volume: 119 Pages: 182-187
- DOI
  10.1016/j.cyto.2019.03.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873, KAKENHI-PROJECT-18K07786, KAKENHI-PROJECT-19K08339
[Journal Article] Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.2019
- Author(s)
  Takakura M, Shimizu M, Irabu H, Sakumura N, Inoue N, Mizuta M, Nakagishi Y, Yachie A.
- Journal Title
  
  Clinical Immunology
  
  Volume: in press Pages: 108252-108252
- DOI
  10.1016/j.clim.2019.108252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08339, KAKENHI-PROJECT-18K07786
[Journal Article] C/EBPε ΔRS derived from a neutrophil-specific granule deficiency patient interacts with HDAC1 and its dysfunction is restored by trichostatin A.2019
- Author(s)
  Muraoka M, Akagi T, Ueda A, Wada T, Koeffler HP, Yokota T, Yachie A.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 516 Issue: 1 Pages: 293-299
- DOI
  10.1016/j.bbrc.2019.06.130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08339
[Journal Article] A case of incomplete Kawasaki disease with extremely high serum ferritin and interleukin-18 levels.2018
- Author(s)
  Noto T, Seto H, Fukuhara J, Murabayashi M, Yachie A, Ayusawa M, Morioka I.
- Journal Title
  
  BMC Pediatr
  
  Volume: 18 Issue: 1 Pages: 386-386
- DOI
  10.1186/s12887-018-1365-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Clinical significance of serum soluble TNF receptor II level and soluble TNF receptor II/I ratio as indicators of coronary artery lesion development in Kawasaki disease.2018
- Author(s)
  Shimizu M, Mizuta M, Usami M, Inoue N, Sakakibara Y, Yamada K, Konishi M, Ohta K, Yachie A.
- Journal Title
  
  Cytokine
  
  Volume: 108 Pages: 168-172
- DOI
  10.1016/j.cyto.2018.03.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Chronic administration of theobromine inhibits mTOR signal in rats.2018
- Author(s)
  Sugimoto N, Katakura M, Matsuzaki K, Sumiyoshi E, Yachie A, Shido O.
- Journal Title
  
  Basic Clin Pharmacol Toxicol.
  
  Volume: 00 Issue: 5 Pages: 1-7
- DOI
  10.1111/bcpt.13175
- NAID
  120007002194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06853, KAKENHI-PROJECT-17H01963, KAKENHI-PROJECT-15KT0003, KAKENHI-PROJECT-16K10064
[Journal Article] Changes in serum interleukin-6 levels as possible predictor of efficacy of tocilizumab treatment in rheumatoid arthritis2018
- Author(s)
  Aizu Motohiko、Mizushima Ichiro、Nakazaki Satoshi、Nakashima Akikatsu、Kato Takashi、Murayama Takashi、Kato Shinichi、Katsuki Yasuo、Ogane Kunihiro、Fujii Hiroshi、Yamada Kazunori、Nomura Hideki、Yachie Akihiro、Yamagishi Masakazu、Kawano Mitsuhiro
- Journal Title
  
  Modern Rheumatology
  
  Volume: 28 Issue: 4 Pages: 592-598
- DOI
  10.1080/14397595.2017.1370766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09083, KAKENHI-PROJECT-15H04873
[Journal Article] Soluble CD163, a unique biomarker to evaluate the disease activity, exhibits macrophage activation in systemic juvenile idiopathic arthritis.2018
- Author(s)
  Sakumura N, Shimizu M, Mizuta M, Inoue N, Nakagishi Y, Yachie A.
- Journal Title
  
  Cytokine
  
  Volume: 110 Pages: 459-465
- DOI
  10.1016/j.cyto.2018.05.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Longitudinal analysis of serum interleukin-18 in patients with familial Mediterranean fever carrying MEFV mutations in exon 10.2018
- Author(s)
  Wada T, Toma T, Miyazawa H, Koizumi E, Shirahashi T, Matsuda Y, Yachie A.
- Journal Title
  
  Cytokine.
  
  Volume: 104 Pages: 143-146
- DOI
  10.1016/j.cyto.2017.10.007
- NAID
  120006464071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Musculoskeletal manifestations occur predominantly in patients with later-onset familial Mediterranean fever: Data from a multicenter, prospective national cohort study in Japan.2018
- Author(s)
  Endo Y, Koga T, Ishida M, Fujita Y, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Umeda M, Fukui S, Nishino A, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Agematsu K, Yachie A, Masumoto J, Migita K, Kawakami A.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 20 Issue: 1 Pages: 257-257
- DOI
  10.1186/s13075-018-1738-1
- NAID
  120006987889
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04873, KAKENHI-PROJECT-17H04656, KAKENHI-PROJECT-17K19685
[Journal Article] Transient natural killer cell dysfunction associated with interleukin-18 overproduction in systemic juvenile idiopathic arthritis.2018
- Author(s)
  Takakura M, Shimizu M, Yakoyama T, Mizuta M, Yachie A.
- Journal Title
  
  Pediatr Int.
  
  Volume: 60 Issue: 10 Pages: 984-985
- DOI
  10.1111/ped.13679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Leucine-rich α2-glycoprotein as the acute-phase reactant to detect systemic juvenile idiopathic arthritis disease activity during anti-interleukin-6 blockade therapy: A case series.2017
- Author(s)
  Shimizu M, Nakagishi Y, Inoue N, Mizuta M, Yachie A.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: Jan 17 Issue: 5 Pages: 1-5
- DOI
  10.1080/14397595.2016.1270795
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873, KAKENHI-PROJECT-26461571
[Journal Article] Interleukin-33 as a marker of disease activity in rheumatoid factor positive polyarticular juvenile idiopathic arthritis.2017
- Author(s)
  Ishikawa S, Shimizu M, Inoue N, Mizuta M, Nakagishi Y, Yachie A.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 27 Issue: 4 Pages: 609-613
- DOI
  10.1080/14397595.2016.1246118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Hypoxia-induced inhibition of the endocannabinoid system in glioblastoma dell.2017
- Author(s)
  Sugimoto N, Ishibashi H, Nakamura H, Yachie A, Ohno-Shosaku Takako.
- Journal Title
  
  Oncology Report
  
  Volume: 38(6) Pages: 3702-3708
- DOI
  10.3892/or.2017.6048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05513, KAKENHI-PROJECT-16K13013, KAKENHI-PROJECT-25000015
[Journal Article] Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice.2017
- Author(s)
  Yoneda M, Sugimoto N, Katakura M, Matsuzaki K, Tanigami H, Yachie A, Ohno-Shosaku T, Shido O.
- Journal Title
  
  J Nutr Biochem.
  
  Volume: 39 Pages: 110-116
- DOI
  10.1016/j.jnutbio.2016.10.002
- NAID
  120005895700
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282021, KAKENHI-PROJECT-26430013, KAKENHI-PROJECT-15KT0003, KAKENHI-PROJECT-16K13013, KAKENHI-PROJECT-25000015
[Journal Article] FDG-PET in macrophage activation syndrome associated with systemic juvenile idiopathic arthritis.2017
- Author(s)
  Shimizu M, Ikawa Y, Mizuta M, Takakura M, Inoue N, Nishimura R, Yachie A.
- Journal Title
  
  Pediatr Int.
  
  Volume: 59 Issue: 4 Pages: 509-511
- DOI
  10.1111/ped.13238
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461571, KAKENHI-PROJECT-15H04873
[Journal Article] Comparison of serum inflammatory cytokine concentrations in familial Mediterranean fever and rheumatoid arthritis patients2017
- Author(s)
  Koga T、Kawashiri S-y、Migita K、Sato S、Umeda M、Fukui S、Nishino A、Nonaka F、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Ueki Y、Masumoto J、Agematsu K、Yachie A、Eguchi K、Kawakami A
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: - Issue: 4 Pages: 1-3
- DOI
  10.1080/03009742.2017.1363281
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-17K09981, KAKENHI-PROJECT-17K19685, KAKENHI-PROJECT-15H04783, KAKENHI-PROJECT-26461481, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-15H04873
[Journal Article] Poly (I:C) and hyaluronic acid directly interact with NLRP3, resulting in the assembly of NLRP3 and ASC in a cell-free system.2017
- Author(s)
  Kaneko N, Ito Y, Iwasaki T, Takeda H, Sawasaki T, Migita K, Agematsu K, Koga T, Kawakami A, Yachie A, Yoshiura K, Morikawa S, Kurata M, Masumoto J.
- Journal Title
  
  European Journal of Inflammation
  
  Volume: 印刷中 Issue: 2 Pages: 85-97
- DOI
  10.1177/1721727x17711047
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293232, KAKENHI-PROJECT-26305024, KAKENHI-PROJECT-17K19685, KAKENHI-PROJECT-17H04656, KAKENHI-PROJECT-17H00599
[Journal Article] Microarray analysis of circulating microRNAs in familial Mediterranean fever.2017
- Author(s)
  Wada T, Toma T, Matsuda Y, Yachie A, Itami S, Taguchi Y, Murakami Y.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: Feb 6 Issue: 6 Pages: 1-18
- DOI
  10.1080/14397595.2017.1285845
- NAID
  120006226806
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873, KAKENHI-PROJECT-15K08649, KAKENHI-PROJECT-15K09642
[Journal Article] MicroRNA-204-3p inhibits lipopolysaccharide-induced cytokines in familial Mediterranean fever via the phosphoinositide 3-kinase γ pathway2017
- Author(s)
  Koga Tomohiro,Migita Kiyoshi,Sato Tomohito,Sato Shuntaro,Umeda Masataka,Nonaka Fumiaki,Fukui Shoichi,Kawashiri Shin-ya,Iwamoto Naoki,Ichinose Kunihiro,Tamai Mami,Nakamura Hideki,Origuchi Tomoki,Ueki Yukitaka,Masumoto Junya,Agematsu Kazunaga,Yachie Akihiro,Yoshiura Koh-ichiro,Eguchi Katsumi,Kawakami Atsushi
- Journal Title
  
  Rheumatology
  
  Volume: 57 Issue: 4 Pages: 718-726
- DOI
  10.1093/rheumatology/kex451
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-17K09981, KAKENHI-PROJECT-16K15514, KAKENHI-PROJECT-26461481, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-16KT0112, KAKENHI-PROJECT-15H04873, KAKENHI-PROJECT-16H05159, KAKENHI-PROJECT-17H04656, KAKENHI-PROJECT-17K19685
[Journal Article] Capsaicin partially mimics heat in mouse fibroblast cells in vitro.2017
- Author(s)
  Sugimoto N, Katakura M, Matsuzaki K, Nakamura H, Yachie A, Shido O.
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol.
  
  Volume: 390 Issue: 3 Pages: 281-289
- DOI
  10.1007/s00210-016-1331-6
- NAID
  120005982994
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282021, KAKENHI-PROJECT-15KT0003, KAKENHI-PROJECT-15K08208, KAKENHI-PROJECT-16K13013
[Journal Article] Characteristic elevation of soluble TNF receptor II : I ratio in macrophage activation syndrome with systemic juvenile idiopathic arthritis2017
- Author(s)
  Shimizu M.、Inoue N.、Mizuta M.、Nakagishi Y.、Yachie A.
- Journal Title
  
  Clinical Experimental Immunology
  
  Volume: 191 Issue: 3 Pages: 349-355
- DOI
  10.1111/cei.13026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461571, KAKENHI-PROJECT-15H04873
[Journal Article] Protein kinase A and Epac activation by cAMP regulate the expression of glial fibrillary acidic protein in glial cells.2016
- Author(s)
  Sugimoto N, Miwa S, Nakamura H, Tsuchiya H, Yachie A.
- Journal Title
  
  Arch Biol Sci.
  
  Volume: 68 Issue: 4 Pages: 795-801
- DOI
  10.2298/abs160112067s
- NAID
  120005982993
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282021
[Journal Article] Serum ferritin levels as a useful diagnostic marker for the distinction of systemic juvenile idiopathic arthritis and Kawasaki disease.2016
- Author(s)
  Mizuta M, Shimizu M, Inoue N, Kasai K, Nakagishi Y, Takahara T, Hamahira K, Yachie A.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 26 Issue: 6 Pages: 929-932
- DOI
  10.3109/14397595.2016.1159120
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Familial Mediterranean fever is no longer a rare disease in Japan.2016
- Author(s)
  Migita K, Izumi Y, Jiuchi Y, Iwanaga N, Kawahara C, Agematsu K, Yachie A, Masumoto J, Fujikawa K, Yamasaki S, Nakamura T, Ubara Y, Koga T, Nakashima Y, Shimizu T, Umeda M, Nonaka F, Yasunami M, Eguchi K, Yoshiura K, Kawakami A.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 18 Issue: 1 Pages: 175-175
- DOI
  10.1186/s13075-016-1071-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04873, KAKENHI-PROJECT-16H05159, KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-26461481
[Journal Article] Role of 18-fluoro-2-deoxyglucose positron emission tomography in detecting acute inflammatory lesions of non-bacterial osteitis in patients with a fever of unknown origin: A comparative study of 18-fluoro-2-deoxyglucose positron emission tomography, bone scan, and magnetic resonance imaging.2016
- Author(s)
  Shimizu M, Saikawa Y, Yachie A.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: Jun 20 Pages: 1-5
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Interleukin-33 as a marker of disease activity in rheumatoid factor positive polyarticular juvenile idiopathic arthritis.2016
- Author(s)
  Ishikawa S, Shimizu M, Inoue N, Mizuta M, Nakagishi Y, Yachie A.
- Journal Title
  
  Mod Rheumatol
  
  Volume: Oct.27 Pages: 1-5
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Angiopoietin-1 and -2 as markers for disease severity in hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli.2016
- Author(s)
  Shimizu M, Inoue N, Kuroda M, Mizuta M, Sugimoto N, Kaneda H, Ohta K, Yachie A.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Disruption of vascular endothelial homeostasis in systemic juvenile idiopathic arthritis-associated macrophage activation syndrome: The dynamic roles of angiopoietin-1 and -2.2016
- Author(s)
  Tasaki Y, Shimizu M, Inoue N, Mizuta M, Nakagishi Y, Wada T, Yachie A.
- Journal Title
  
  Cytokine.
  
  Volume: 80 Pages: 1-6
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] Interleukin-18 for predicting the development of macrophage activation syndrome in systemic juvenile idiopathic arthritis.2015
- Author(s)
  Shimizu M, Nakagishi Y, Inoue N, Mizuta M, Ko G, Saikawa Y, Kubota T, Yamasaki Y, Takei S, Yachie A.
- Journal Title
  
  Clin Immunol.
  
  Volume: 160 Pages: 277-281
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] A Novel In-Frame Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency.2015
- Author(s)
  Wada T, Akagi T, Muraoka M, Toma T, Kaji K, Agematsu K, Koeffler HP, Yokota T, Yachie A.
- Journal Title
  
  J Immunol.
  
  Volume: 195 Pages: 180-6
- NAID
  120005647665
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils.2015
- Author(s)
  Lin HT, Masaki H, Yamaguchi T, Wada T, Yachie A, Nishimura K, Ohtaka M, Nakanishi M, Nakauchi H, Otsu M.
- Journal Title
  
  Mol Ther Methods Clin Dev.
  
  Volume: 2 Pages: 15046-15046
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04873
[Journal Article] The critical role of lipopolysaccharide in the upregulation of aquaporin 4 in glial cells treated with Shiga toxin.2015
- Author(s)
  Sugimoto N, Leu H, Inoue N, Shimizu M, Toma T, Kuroda M, Saito T, Wada T, Yachie A.
- Journal Title
  
  J Biomed Sci
  
  Volume: 22 Issue: 1 Pages: 78-78
- DOI
  10.1186/s12929-015-0184-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09642, KAKENHI-PROJECT-26650173, KAKENHI-PROJECT-24390420, KAKENHI-PROJECT-25282021
[Journal Article] Long-term Heat Exposure Prevents Hypoxia-Induced Apoptosis in Mouse Fibroblast Cells2014
- Author(s)
  Sugimoto N, Shido O, Matsuzaki K, Katakura M, Hitomi Y, Tanaka M, Sawaki T, Fujita Y, Kawanami T, Masaki Y, Okazaki T, Nakamura H, Koizumi S, Yachie A and Umehara H
- Journal Title
  
  Cell biochemistry and biophysics
  
  Volume: (in press) Issue: 1 Pages: 301-7
- DOI
  10.1007/s12013-014-9912-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249041, KAKENHI-PROJECT-23590278, KAKENHI-PROJECT-24590300, KAKENHI-PROJECT-24659105, KAKENHI-PROJECT-25282021, KAKENHI-PROJECT-25460830, KAKENHI-PROJECT-25670295, KAKENHI-PROJECT-26650173
[Journal Article] Shiga toxin-2 enhances heat-shock-induced cell death in cultured and primary glial cells.2014
- Author(s)
  Sugimoto N, Toma T, Shimizu M, Kuroda M, Wada T, Yachie A.
- Journal Title
  
  Cell Biol Toxicol
  
  Volume: 30 Issue: 5 Pages: 289-299
- DOI
  10.1007/s10565-014-9286-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390420, KAKENHI-PROJECT-24591542, KAKENHI-PROJECT-24591572, KAKENHI-PROJECT-25282021, KAKENHI-PROJECT-26650173
[Journal Article] Rotavirus gastroenteritis-associated urinary ammonium acid urate crystals2014
- Author(s)
  Yokoyama T, Sugimoto N, Kato E, Ohta K, Ishikawa S, Ueno K, Shimizu M, Yachie, A
- Journal Title
  
  Pediatrics International
  
  Volume: 57 Issue: 1 Pages: 158-160
- DOI
  10.1111/ped.12405
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23591591, KAKENHI-PROJECT-24591572, KAKENHI-PROJECT-25282021, KAKENHI-PROJECT-26650173
[Journal Article] Theobromine, the primary methylxanthine found in Theobroma cacao, prevents malignant glioblastoma proliferation by negatively regulating phosphodiesterase-4, extracellular signal-regulated kinase, Akt/mammalian target of rapamycin kinase, and nuclear factor-kappa B2014
- Author(s)
  Sugimoto N, Miwa S, Hitomi Y, Nakamura H, Tsuchiya H, Yachie A
- Journal Title
  
  Nutr Cancer
  
  Volume: 66(3) Issue: 3 Pages: 419-23
- DOI
  10.1080/01635581.2013.877497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390360, KAKENHI-PROJECT-24591572, KAKENHI-PROJECT-24659105, KAKENHI-PROJECT-25282021, KAKENHI-PROJECT-25460830, KAKENHI-PROJECT-25670295
[Journal Article] Soluble ST2 as a marker of disease activity in systemic juvenile idiopathic arthritis.2013
- Author(s)
  Ishikawa S, Shimizu M, Ueno K, Sugimoto N, Yachie A.
- Journal Title
  
  Cytokine
  
  Volume: 62 Issue: 2 Pages: 272-277
- DOI
  10.1016/j.cyto.2013.03.007
- NAID
  130007956852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659105, KAKENHI-PROJECT-25282021
[Journal Article] Upregulation of aquaporin expression in the salivary glands of heat-acclimated rats2013
- Author(s)
  Sugimoto N, Matsuzaki K, Ishibashi H, Tanaka M, Sawaki T, Fujita Y, Kawanami T, Masaki Y, Okazaki T, Sekine J, Koizumi S, Yachie A, Umehara H and Shido O
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 1763-1763
- DOI
  10.1038/srep01763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249041, KAKENHI-PROJECT-23590278, KAKENHI-PROJECT-24591572, KAKENHI-PROJECT-24659105, KAKENHI-PROJECT-24791010, KAKENHI-PROJECT-25282021
[Journal Article] Targeted activation of PKA and Epac promotes glioblastoma regression in vitro2013
- Author(s)
  Sugimoto N, Miwa S, Tsuchiya H, Hitomi Y, Nakamura H, Yachie A, Koizumi S
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 1(2) Issue: 2 Pages: 281-285
- DOI
  10.3892/mco.2013.65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390160, KAKENHI-PROJECT-24591572, KAKENHI-PROJECT-24659105, KAKENHI-PROJECT-25282021
[Journal Article] Expansion of a liver-infiltrating cytotoxic T-lymphocyte clone in concert with the development of hepatitis-associated aplastic anemia2013
- Author(s)
  Ikawa, Y., Nishimura, R., Kuroda, R., Mase, S., Araki R., Maeba, H., Wada, T., Toma, T., Koizumi, S., Yachie, A.
- Journal Title
  
  Brit J Haematol
  
  Volume: 161(4) Pages: 599-602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Upregulation of aquaporin expression in the salivary glands of heat-acclimated rats2013
- Author(s)
  Sugimoto, N., Matsuzaki, K., Ishibashi, H., Tanaka, M., Sawaki, T., Fujita, Y., Kawanami, T., Masaki, Y., Okazaki, T., Sekine, J., Koizumi, S., Yachie, A., Shido, O.
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Pages: 1763-1763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Lactobacillus casei cell wall extract directly stimulates the expression of COX2 independent of Toll-like receptor 2 in rat glial cells2013
- Author(s)
  Sugimoto N, Ohta K, Saito T, Nakayama Y, Nakamura T, Maeda A, Yachie A.
- Journal Title
  
  J Microbiol Immunol Infect.
  
  Volume: 46 Issue: 5 Pages: 389-92
- DOI
  10.1016/j.jmii.2012.03.004
- NAID
  120004161555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591572, KAKENHI-PROJECT-24659105, KAKENHI-PROJECT-25282021
[Journal Article] An infant with recurrent convulsive seizures of 3 weeks duration: Questions2013
- Author(s)
  Shimizu M
- Journal Title
  
  Pediatric Nephrology
  
  Volume: 13 Issue: 10 Pages: 1951-1951
- DOI
  10.1007/s00467-013-2615-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Enhanced exon 2 skipping caused by c.910G>A variant and alternative splicing of MEFV genes in two independent cases of familial Mediterranean fever2012
- Author(s)
  Tone Y, Toma T, Toga A, Sakakibara Y, Wada T, Yabe M, Kusafuka H, Yachie A
- Journal Title
  
  Mod Rheumatol
  
  Volume: 22 Issue: 1 Pages: 45-51
- DOI
  10.1007/s10165-011-0461-4
- NAID
  10030206766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591152
[Journal Article] Tocilizumab masks the clinical symptoms of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome : the diagnostic significance of interleukin-18 and interleukin-62012
- Author(s)
  Shimizu M, Yachie A, et al
- Journal Title
  
  Cytokine
  
  Volume: 58 Pages: 287-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590613
[Journal Article] 38-year-old woman with recurrent abdominal pain, but no fever2012
- Author(s)
  Iwata K, Toma T, Yachie A
- Journal Title
  
  Int J Gen Med.
  
  Volume: 5 Pages: 265-8
- DOI
  10.2147/ijgm.s30867
- NAID
  120005674090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591152
[Journal Article] Characterization of Epstein-Barr virus(EBV)-infected cells in EBV-associated hemophagocytic lympho-histiocytosis in two patients with X-linked lymphoproliferative syndrome type 1 and type 22012
- Author(s)
  Yang X, Wada T, Imadome K, Nishida N, Mukai T, Fujiwara M, Kawashima H, KatoF, Fujiwara S, Yachie A, Zhao X, Miyawaki T, Kanegane H
- Journal Title
  
  Herpesviridae
  
  Volume: 3 Pages: 1-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591353
[Journal Article] Familial Mediterranean fever in Japan2012
- Author(s)
  Migita K, Uehara R, Nakamura Y , Yasunami M, Tsuchiya-Suzuki A, Yazaki M
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 91 Issue: 6 Pages: 337-343
- DOI
  10.1097/md.0b013e318277cf75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590332, KAKENHI-PROJECT-22591094, KAKENHI-PROJECT-22591152, KAKENHI-PUBLICLY-24117710, KAKENHI-PUBLICLY-24117721
[Journal Article] Cellular Heat Acclimation Regulates Cell Growth, Cell Morphology, Mitogen-activated Protein Kinase Activation, and Expression of Aquaporins in Mouse Fibroblast Cells.2012
- Author(s)
  N Sugimoto, O Shido, K Matsuzaki, T Ohno-Shosaku, Y Hitomi, M Tanaka, T Sawaki, Y Fujita, T Kawanami, Y Masaki, T Okazaki, H Nakamura, S Koizumi, A Yachie, H Umehara
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 30 Pages: 450-457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Compensated inflammation in systemic juvenile idiopathic arthritis : role of alternatively activated macrophages2012
- Author(s)
  Shimizu M., Yachie, A.
- Journal Title
  
  Cytokine
  
  Volume: 60(1) Pages: 226-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Multiple reversions of an IL2RG mutation restore T cell function in an X-linked severe combined immunodeficiency patient2012
- Author(s)
  Kawai T, Yachie A, et al
- Journal Title
  
  J Clin Immunol
  
  Volume: 30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590613
[Journal Article] Phosphodiesterase inhibitors suppress Lactobacillus casei cell wall-induced NF-kB and MAPK activation, and cell proliferation through a protein kinase A- or exchange protein activated by cAMP-dependent signal pathway.2012
- Author(s)
  Saito T, Sugimoto N, Ohta K, Shimizu T, Phtani K, Nakayama Y, Nakanuma T, Hitomi Y, Nakamura H, Koizumi S, Yachie A.
- Journal Title
  
  The Scientific World Journal
  
  Volume: 2012 Pages: 8-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Urinary Heme Oxygenase-1 as a Sensitive Indicator of Tubulointerstitial Inflammatory Damage in Various Renal Diseases.2011
- Author(s)
  Yokoyama T, Shimizu M, OhtaK, Yuno T, Okajima M, WadaT, Toma T, Koizumi S, Yachie A:
- Journal Title
  
  Am J Nephrol
  
  Volume: 33 Pages: 414-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Aplastic anemia successfully treated with rituximab: the possible role of　aplastic anemia-associated autoantibodiesas a marker for response2011
- Author(s)
  Hiroyuki Takamatsu, Hiroshi Yagasaki, Yoshiyuki Takahashi, Asahito Hama, Yutaka Saikawa,Akihiro Yachie, Shoichi Koizumi, Seiji Kojima, Shinji Nakao
- Journal Title
  
  European Journal of Haematology
  
  Volume: 86 Pages: 541-545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Human heme oxygenase-1 deficiency presenting with hemolysis, nephritis, and asplenia2011
- Author(s)
  Radhakrishnan N, Yachie A, et al
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 33 Pages: 74-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590613
[Journal Article] Activation of tumor suppressor protein PTEN and induction ofapoptosis are involved incAMP-mediated inhibition ofcell number in B92 glial cells.2011
- Author(s)
  Naotoshi Sugimoto, Shinji Miwa, Takako Ohno-Shosaku, Hiroyuki Tsuchiya, Yoshiaki Hitomi, HiroyukiNakamura, Katsuro Tomita, Akihiro Yachie, Shoichi Koizumi
- Journal Title
  
  Neuroscience
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Activation of tumor suppressor protein PTEN and induction of apoptosis are involved in cAMP-mediated inhibition of cell number in B92 glial cells.2011
- Author(s)
  Naotoshi Sugimoto, Shinji Miwa, Takako Ohno-Shosaku, Hiroyuki Tsuchiya, Yoshiaki Hitomi, Hiroyuki Nakamura, Katsuro Tomita, Akihiro Yachie, Shoichi Koizumi
- Journal Title
  
  Neuroscience Letters
  
  Volume: 497 Pages: 55-59
- NAID
  120003141599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Human heme oxygenase(HO)-1 deficiency presenting with hemolysis, nephritis and asplenia.2011
- Author(s)
  Nita Radhakrishnan, S Prakash Yadav, Taizo Wada, Akihiro Yachie
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 33 Pages: 74-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Human heme oxygenase (HO)-1 deficiency presenting with hemolysis, nephritisand asplenia.2011
- Author(s)
  Nita Radhakrishnan, S Prakash Yadav, Taizo Wada, Akihiro Yachie
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 33 Pages: 74-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Human heme oxygenase-1deficiency presenting with hemolysis, nephritis and asplenia2011
- Author(s)
  Radhakrishnan N, Yadav SP, SachdevaA, Pruthi PK, Sawhney S, Piplani T, WadaT, Yachie A
- Journal Title
  
  J PediatrHematol/Oncol
  
  Volume: 33 Pages: 74-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591413
[Journal Article] Urinary heme oxygenase-1 as a sensitive indicator of tubulointerstitial inflammatory damage in various renal diseases2011
- Author(s)
  Yokoyama, T., Shimizu, M., Ohta, K., Yuno, T., Okajima, M., Wada, T., Toma, T., Koizumi, S., Yachie, A.
- Journal Title
  
  Am J Nephrol
  
  Volume: 33 Pages: 414-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Human Heme oxygenase (HO)-1 deficiency presenting with hemolysis, nephritisand asplenia2011
- Author(s)
  Radhakrishnan,N., Yadav,S.P., Sachdeva,A., Pruthi,P.K., Sawhney,S., Piplani,T., Wada,T., Yachie,A.
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 33(1) Pages: 74-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Journal Article] Effects of antithrombin III treatment in vascular in vascular injury model of mice2011
- Author(s)
  Maeda A, Yachie A, et al
- Journal Title
  
  Pediatr Int
  
  Volume: 53 Pages: 747-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590613
[Journal Article] Human heme oxygenase (HO)-1 deficiency presenting with hemolysis, nephritisand asplenia.2011
- Author(s)
  Nita Radhakrishnan, Satya Prakash Yadav, Anuppam Sachdeva, Praveen K Pruthi, Sujata Sawhney, Tarun Piplani, Taizo Wada, Akihiro Yachie
- Journal Title
  
  J Pediatr Hematol Oncol 33(1)
  
  Pages: 74-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Clinical significance of cloned expansion and CD5 down-regulation in Epstein-Barr Virus(EBV)-infected CD8^+T lymphocytes in EBV-associated hemophagocytic lympho-histiocytosis2010
- Author(s)
  Toga A, Wada T, Sakakibara Y, Mase S, Araki R, Tone Y, Toma T, Kurokawa T, Yanagisawa R, Tamura K, Nishida N, Taneichi H, Kanegane H, Yachie A.
- Journal Title
  
  J Infect Dis
  
  Volume: 201 Pages: 1923-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591353
[Journal Article] Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis2010
- Author(s)
  Shimizu M, Yachie A, et al
- Journal Title
  
  Rheumatiology
  
  Volume: 49 Pages: 1645-1653
- NAID
  120002463521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590613
[Journal Article] Dense methylation of type 1 and type 2 regulatory regions of the CD10 gene promoter in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene.2010
- Author(s)
  Ikawa Y, Sugimoto N, Koizumi S, Yachie A, Saikawa Y.
- Journal Title
  
  J Pediatric Hematology Oncology
  
  Volume: 32 Pages: 4-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Accelerated production ofmultiple cytokines and chemokines by Epstein-Barrvirus-infected natural killer cells and T cells.2010
- Author(s)
  Mika Inoue, Yoshihito Kasahara, Michiko Okajima, Taizo Wada, Tomoko Toma, Masaki Shimizu, Shoichi Koizumi, Akihiro Yachie
- Journal Title
  
  J Juzen Medical Society
  
  Volume: 119 Pages: 154-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Distinct cytokine profiles of systemic-onset juvenile, idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 ini ts pathogenesis2010
- Author(s)
  Shimizu M, Yokoyama T, Yamada K, Kaneda H, Wada H, Wada T, Toma T, OhtaK, Kasahara Y, Yachie A
- Journal Title
  
  Rheumatology
  
  Volume: 49 Pages: 1645-1653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591413
[Journal Article] Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis2010
- Author(s)
  Shimizu M, Yokoyama T, Yamada K, Kaneda H, Wada H, Wada T, Toma T, OhtaK, Kasahara Y, Yachie A
- Journal Title
  
  Rheumatology
  
  Volume: 49 Pages: 1645-53
- NAID
  120002463521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591353
[Journal Article] Dense methylation of type1 and type2 regulatory regions of the CD10 gene promoter in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene.2010
- Author(s)
  Ikawa Y, Sugimoto N, Koizumi S, Yachie A, Saikawa Y.
- Journal Title
  
  J Pediatric Hematology Oncology 32(1)
  
  Pages: 4-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Curcumin-induced modulationof inflammatory cytokine production bycirculating mononuclear cells via hemeoxygenase-12009
- Author(s)
  Futaki T, Ei K, Shigeki O, Hiroshi N, Yachie A
- Journal Title
  
  金沢大学つるま保健学会雑誌
  
  Volume: 33 Pages: 11-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591413
[Journal Article] Strong Inhibition of Alloreaction by Newly Generated Tolerogenic Dendritic Cells by Psoralen Plus UVA Treatment2009
- Author(s)
  Maeba H, Nishimura R, Kuroda R, Araki R, Mase S, Ikawa Y, Yachie A, Koizumi S.
- Journal Title
  
  Blood (ASH Annual Meeting Abstracts) 114
  
  Pages: 3686-3686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] ヘモオキシナーゲ. 1(HO-1)による血管内皮細胞上の組織因子、トロンボモジュリンの調節2009
- Author(s)
  丸山慶子、森下英理子、關谷暁子、長屋聡美、角野忠昭、朝倉英策、中尾眞二、大竹茂樹、谷内江昭宏
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 20 Pages: 316-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591413
[Journal Article] Flow cytometric analysis of skin blister fluid induced by mosquito bites in a patient with chronic active Epstein-Barr virus infection2009
- Author(s)
  Wada T, Yokoyama T, Nakagawa H, AsaiE, Toga A, Sakakibara Y, Shibata F, Tone Y, Shimizu M, Toma T, Yachie A
- Journal Title
  
  Int J Hematol
  
  Volume: 90 Pages: 611-5
- NAID
  10026110032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591353
[Journal Article]2008
- Author(s)
  Wada T, Yasui M, Toma T, Nakayama Y,Nishida M, Shimizu M, Okajima M, Kasahara Y, Koizumi S, Inoue M, Kawa K, Yachie A
- Journal Title
  
  Blood 112
  
  Pages: 1872-1875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591244
[Journal Article] Analysis of T cell receptor Vb diversity in peripheral CD4^+ and CD8^+ T lymphocytes in patients with autoimmune thyroid diseases2008
- Author(s)
  Okajima M, Wada T, Nishida M, Yokoyama T, Nakayama Y, Hashida Y, Shibata F, Tone Y, Ishizaki A, Shimizu M, Saito T, Ohta K, Toma T, Yachie A.
- Journal Title
  
  Clin Exp Immunol 155
  
  Pages: 166-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591244
[Journal Article] Detection of T lymphocytes with a second-site mutation in skin lesions of atypical X-linked severe combined immunodeficiency mimicking Omenn syndrome.2008
- Author(s)
  Wada T, Yasur M, Toma T, Nakayama Y, Nishida M, Shimizu M, Okajima M, Kasahara Y, Koizumi S, Inoue M, Kawa K, Yachie A
- Journal Title
  
  Blood 112
  
  Pages: 1872-1875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Detection of T lymphocytes with a second-site mutation in skin lesions of atypical X-linked severe combined immunodeficiency mimicking Omenn syndrome.2008
- Author(s)
  Wada T, Yasui M, Toma T, Nakayama Y, Nishida M, Shimizu M, Okajima M, Kasahara Y, Koizumi S, Inoue M, Kawa K, Yachie A.
- Journal Title
  
  Blood 112(5)
  
  Pages: 1872-1875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Clonal relationship between infiltrating immunoglobulin G4 (IgG4)-positive plasma cells in lacrimal glands and circulating IgG4-positive lymphocytes in Mikulicz's disease2008
- Author(s)
  Yamada, K., Kawano, M., Inoue, R., Hamano, R., Kakuchi, Y., Fujii, H., Matsumura, M., Zen, Y., Takahira, M., Yachie, A., Yamagishi, M
- Journal Title
  
  Clin Exp Immunol 152(3)
  
  Pages: 432-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Skin infiltration of CD56(bright) CD16(-) natural killer cells in a case of X-SCID with Omenn syndrome-like manifestations2007
- Author(s)
  Shibata, F., Toma, T., Wada, T., Inoue, M., Tone, Y., Ohta, K., Kasahara, Y., Sano, F., Kimura, M., Ikeno, M., Koizumi, S., Yachie, A
- Journal Title
  
  Eur J Haematol 79(1)
  
  Pages: 81-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Corticosteroid enhances heme oxygenase-1 production by circulating monocytes by up-regulating hemoglobin scavenger receptor and amplifying the receptor-mediated uptake of hemoglobin-haptoglobin complex2007
- Author(s)
  Yamazaki, H., Ohta, K., Tsukiji, H., Tema, T., Hashida, Y., Ishizaki, A., Saito, T., Arai, S., Koizumi, S., Yachie, A
- Journal Title
  
  Biochem Biophys Res Commun 358(2)
  
  Pages: 506-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Reactive peripheral blood plasmacytosis in a patient with acute hepatitis A2007
- Author(s)
  Wada, T., Maeba, H., Ikawa, Y., Hashida, Y., Okumura, A., Shibata, F., Tone,. Y, Inoue, M., Koizumi, S, Takatori H, Sakai Y ; Kaneko S, Yachie, A
- Journal Title
  
  Int J Hematol 85(3)
  
  Pages: 191-4
- NAID
  10019488769
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Sequential measurement of fecal parameters in a case of non- immunoglobulin E-mediated milk allergy2007
- Author(s)
  Wada, H., Horisawa, T., Inoue, M., Yoshida, T., Toma, T., Yachie, A
- Journal Title
  
  Pediatr Int 49(1)
  
  Pages: 109-11
- NAID
  10018837878
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Immunophenotypic analysis of Epstein-Barr virus (EBV)-infected CD8(÷) T cells in a patient with EBV-associated hemophagocytic lymphohistiocytosis2007
- Author(s)
  Wada, T., Kurokawa, T., Toma, T., Shibata, F., Tone, Y., Hashida, Y., Kaya, H., Yoshida, T., Yachie, A
- Journal Title
  
  Eur J Haematol 79(1)
  
  Pages: 72-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Heme oxygenase and its role in defense system ; paradigm shift of anti-inflammatory therapy2007
- Author(s)
  Yachie, A
- Journal Title
  
  Nihon Rinsho Meneki Gakkai Kaishi 30(1)
  
  Pages: 11-21
- NAID
  10018857951
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] ヘムオキシゲナーゼと生体防御機構 : 抗炎症治療のパラダイムシフト2007
- Author(s)
  谷内江昭宏
- Journal Title
  
  日本臨床免疫学会会誌 30・1
  
  Pages: 11-21
- NAID
  10018857951
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Somatic revertant mosaicism in a patient with leukocyte adhesion deficiency type 12007
- Author(s)
  Tone, Y., Wada, T., Shibata, F., Toma, T., Hashida, Y., Kasahara, Y., Koizumi, S., Yachie, A
- Journal Title
  
  Blood 109(3)
  
  Pages: 1182-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] ヘムオキシゲナーゼと生体防御機構;抗炎症治療のパラダイムシフト2007
- Author(s)
  谷内江昭宏
- Journal Title
  
  日本臨床免疫学会会誌 30(1)
  
  Pages: 11-21
- NAID
  10018857951
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Immunophenotypic analysis of Epstein-Barr virus(EBV)-infected CD8^+ T cells in a patient with EBV-associated hemophagocytic lymphohistiocytosis2007
- Author(s)
  Wada T, Kurokawa T, Toma T, Shibata F, Tone Y, Hashida Y, Kaya H, Yoshida T, Yachie A.
- Journal Title
  
  Eur J Haematol 79
  
  Pages: 72-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591244
[Journal Article] heme oxygenase, and ferritin : how the vascular endothelium survives (and dies) in an iron-rich environment. Antioxid Redox Signal2007
- Author(s)
  Balla, J., Vercellotti, GM., Jeney, V., Yachie, A., Varga, Z., Jacob, HS., Eaton, JW., Balla, G. Heme
- Journal Title
  
  Antioxid Redox Signal 9(12)
  
  Pages: 2119-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Skin infiltration of CD56^<bright> CD16^- natural killer cells in a case of X-SCID with Omenn syndrome-like manifestations2007
- Author(s)
  Shibata F, Toma T, Wada T, Inoue M, Tone Y, Ohta K, Kasahara Y, Sano F, Kimura M, Ikeno M, Koizumi S, Yachie A.
- Journal Title
  
  Eur J Haematol 79
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591244
[Journal Article] Clonotypic analysis of T cell reconstitution after haematopoietic stem cell transplantation (HSCT) in patients with severe combined immunodeficiency2007
- Author(s)
  Okamoto H, Arii C, Shibata F, Toma T, Wada T, Inoue M, Tone Y, Kasahara Y, Koizumi S, Kamachi Y, Ishida Y, Inagaki J, Kato M, Morio T, Yachie A.
- Journal Title
  
  Clin Exp Immunol 148
  
  Pages: 45-460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591244
[Journal Article] Corticosteroid enhances heme oxygenase-1 production by circulating monocytes by up-regulating hemoglobin scavenger receptor and amplifying the receptor-mediated uptake of hemoglobin-haptoglobin complex2007
- Author(s)
  Yamazaki H, Ohta K, Tsukiji H, Toma T, Hashida Y, Ishizaki A, Saito T, Arai S, Koizumi S, Yachie A.
- Journal Title
  
  Biochem Biophys Res Commun 358
  
  Pages: 506-512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591244
[Journal Article] Clonotypic analysis of T cell reconstitution after haematopoietic stem cell transplantation (HSCT) in patients with severe combined immunodeficiency2007
- Author(s)
  Okamoto, H., Arii, C., Shibata, F., Toma, T., Wada, T., Inoue, M., Tone, Y., Kasahara, Y., Koizumi, S., Kamachi, Y., Ishida, Y., Inagaki, J., Kato, M., Morio, T., Yachie, A
- Journal Title
  
  Clin Exp Immunol 148(3)
  
  Pages: 450-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] ヘムオキシゲナーゼと生体防御機構;抗炎症治療のパラダイムシフト2007
- Author(s)
  谷内江昭宏
- Journal Title
  
  Jpn J CIin Immunol 30
  
  Pages: 11-12
- NAID
  10018857951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591244
[Journal Article] Analysis of MPO-ANCA subtypes in a patient with propylthiouracil-induced vasculitis with multiple2007
- Author(s)
  Ohta, K., Shimizu, M., Yokoyama, T., Ohta, K., Nakai, A., Seno, A., Kasahara, Y., Yachie, A., Fujieda, M., Koizumi, S
- Journal Title
  
  Clin Nephrol 68(5)
  
  Pages: 315-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Role Of T cells in the pathogenesis of type I diabetes mellitus : structure analysis of complementarity determining region 3 of circulating T cells2007
- Author(s)
  Sakumai, M., Yachie, A., Kasahara, Y
- Journal Title
  
  Rinsho Byori 55(2)
  
  Pages: 112-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Neuromyelitis optica associated with myasthenia gravis : characteristic phenotype in Japanese population2006
- Author(s)
  Furukawa, Y., Yoshikawa, H., Yachie, A., Yamada, M
- Journal Title
  
  Eur J Neurol 13(6)
  
  Pages: 655-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] second-site mutation in the initiation codon of WAS (WASP) results in expansion.of subsets of lyphocytes in an Wiskott-Aldrich syndrome patient2006
- Author(s)
  Du, W., Kumaki, S., Uchiyama, T.,Yachie, A., Yeng Looi, C., Kawai, S., Minegishi, M., Ramesh, N., Geha, RS., Sasahara, Y., Tsuchiya, S.,A
- Journal Title
  
  Hum Mutat 27(4)
  
  Pages: 370-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Rituximab therapy for Epstein-Barr virus-related chronic hepatitis following living donor kidney transplantation2006
- Author(s)
  Ohta, K., ShiMizu, M., Nakai, A., Toma, T., KaSahare, Y., Arii, C., Yachie, A., Kawamura, T., Aikawa, A., Hasegawa, A., Sato, K., Yokoyama, H., Ishikawa, I., Koizumi, S
- Journal Title
  
  Am J Kidney Dis 48(6)
  
  Pages: 986-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Cytomegalovirus-associated protracted diarrhoea in an immunocompetent boy2006
- Author(s)
  Shimizu, M., Ohta, K., Wada, H., Sumita, R., Yachie, A., Koizumi, S
- Journal Title
  
  J Paediatr Child Health 42(5)
  
  Pages: 259-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity2006
- Author(s)
  Minegishi, Y., Saito, M., Mario, T ; Watanabe, K., Agematsu, K., Tsuchiya, S., Takada, H., Hara, T., Kawamura, N., Ariga, T, Kaneko, H., Kondo, N., Tsuge, L., Yachie, A. Sakiyama, Y., Iwata, T., Bessho, F., Ohishi, T., Joh, K., Imai, K., Kogawa, K., Shinohara, M., Fujieda, M., Wakiguchi, H., Paste, S., Abinun, M., Ochs, HD., Renner, ED., Janssen, A., Belohradsky, BH., Metin, A., Shimizu, N., Mizutani, S., Miyawaki, T., Nonoyama, S., Karasuyama, H
- Journal Title
  
  Immunity 25(5)
  
  Pages: 745-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Somatic revertant mosaicism in a patient with leukocyte adhesion deficiency type 12006
- Author(s)
  Tone, Y., Wada, T., Shibata, F., Toma, T., Hashida, Y., Kasahara, Y., Koizumi, S., Yachie, A
- Journal Title
  
  Blood (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Omenn syndrome-review of several phenotypes of Omenn syndrome and RAG1/RAG2 mutations in Japan2006
- Author(s)
  Kato, M., Kimura, H., Seki, M., Shimada, A., Hayashi, Y., Morio, T., Kumaki, S., Ishida, Y., Kamachi, Y., Yachie, A
- Journal Title
  
  Allergol Int. Review 55(2)
  
  Pages: 115-9
- NAID
  10019169596
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Journal Article] Selective expansion of CD16^<high>CCR2^- subpopulation of circulating monocytes with preferential production of haem oxygenase (HO)-1 in response to acute inflammation.2005
- Author(s)
  Mizuno K, Toma T, Yachie A, et al.
- Journal Title
  
  Clin Exp Immunol 142
  
  Pages: 462-470
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Development of vascular biology over the past 10 years : heme oxygenase-1 in cardiovascular homeostasis.2005
- Author(s)
  Ohta K, Yachie A
- Journal Title
  
  J Endovasc Ther Suppl 2:II
  
  Pages: 140-150
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Selective expansion of CD 16highCCR2- subpopulation of circulating monocytes with preferential production of haem oxygenase (HO)-1 in response to acute inflammation.2005
- Author(s)
  Mizuno K, Toma T, Yachie A, et al.
- Journal Title
  
  Clin Exp Immunol. 142
  
  Pages: 462-470
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Oxidation of hemoglobin by lipid hydroperoxide associated with low-density lipoprotein (LDL) and increased cytotoxic effect by LDL oxidation in heme oxygenase-1 (HO-1) deficiency.2005
- Author(s)
  Nagy E, Jeney V, Yachie A, et al.
- Journal Title
  
  Cell Mol Biol 51
  
  Pages: 377-385
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Glomerular protemuria induces heme oxygenase-1 gene expression within renal epithelial cells.2005
- Author(s)
  Shimizu M, Ohat K, Yang Y, Nakai A, Yachie A. et al.
- Journal Title
  
  Pediatr Res 58
  
  Pages: 666-671
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Glomerular proteinuria induces heme oxygenase-1 gene expression within renal epithelial cells.2005
- Author(s)
  Shimizu M, Ohta K, Yang Y, Nakai A, Yachie A., et al.
- Journal Title
  
  Pediatr Res 58
  
  Pages: 666-671
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Heme, heme oxygenase and ferritin in vascular endothelial cell injury.2005
- Author(s)
  Balla J, Vercellotii GM, Jeney V, Yachie A. et al.
- Journal Title
  
  Nol Nutr Food Res 49
  
  Pages: 1030-1043
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Heme, heme oxygenase and ferritin in vascular endothelial cell injury.2005
- Author(s)
  Balla J, Vercellotti GM, Jeney V, Yachie A, et al.
- Journal Title
  
  Mol Nutr Food Res 49
  
  Pages: 1030-1043
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Regulation of airway inflammation and heme oxygenase/CO2005
- Author(s)
  Yachie A
- Journal Title
  
  Allery/Immunology (Japanese) 12
  
  Pages: 772-778
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Selective expansion of CD16^<high> CCR2- subpopulation of circulating monocytes with preferential production of haem oxygenase (HO)-1 in response to acute inflammation.2005
- Author(s)
  Mizuno K, Toma T, Yachie A, et al.
- Journal Title
  
  Clin Exp Immunol 142
  
  Pages: 462-470
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Oxidation of hemoglobin by lipid hydroperoxide associated with low-density lipoprotein (LDL) and increased cytotoxic effect by LDL oxidation in heme oxygenase-1 (HO-1) deficiency.2005
- Author(s)
  Nagy B, Jeney V, Yachie A, et al.
- Journal Title
  
  Cell Mol Biol 51
  
  Pages: 377-385
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Oxidation of hemoglobin by lipid hydroperoxide associated with low-density lipoprotein (LDL) and increased cytotoxic effect by LDL oxidation in heme oxygenase-1 (HO-1) deficiency.2005
- Author(s)
  Nagy E, Jeney V, Yachie A. et al.
- Journal Title
  
  Cell Mol Biol 51
  
  Pages: 377-385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] 気道炎症制御とヘムオキシゲナーゼ、CO2005
- Author(s)
  谷内江昭宏
- Journal Title
  
  アレルギー・免疫 12
  
  Pages: 772-778
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Glomerular proteinuria induces heme oxygenase-1 gene expression within renal epithelial cells.2005
- Author(s)
  Shimizu M, Ohta K, Yang Y, Nakai A, Yachie A, et al.
- Journal Title
  
  Pediatr Res 58
  
  Pages: 666-671
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] 気道炎症制御とヘムオキシゲナーゼ、CO2005
- Author(s)
  谷内江昭宏
- Journal Title
  
  アレルギー・免疫 12
  
  Pages: 772-778
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Heme, heme oxygenase and ferritin in vascular endothelial cell injury.2005
- Author(s)
  Balla J, Vercelloffi GM, Jeney V, Yachie A., et al.
- Journal Title
  
  Mol Nutr Food Res. 49
  
  Pages: 1030-1043
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] アレルギー・免疫疾患とレドックス制御:気管炎症制御とヘムオキシナーゼ、CO2005
- Author(s)
  谷内江昭宏
- Journal Title
  
  アレルギー・免疫 in press
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Paradoxical enhancement of oxidative cell injury by overexpression of heme oxyegnase-1 in an anchorage-dependent cell ECV304.2004
- Author(s)
  Maruhashi K, Kasahara Y, Ohta K, Wada T, Ohta K, Nakamura N, Toma T, Koizumi S, Yachie A
- Journal Title
  
  J Cell Biochem 93
  
  Pages: 552-562
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Paradoxical enhancement of oxidative cell injury by overexpression of heme oxygenase-1 in an anchorage-dependent cell ECV304.2004
- Author(s)
  Maruhashi K, Kasahara Y, Ohta K, Wada T, Ohta K, Nakamura N, Toma T, Koizumi S, Yachie A
- Journal Title
  
  J Cell Biochem 93
  
  Pages: 552-562
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Development of vascular biology over the past 10 years ; heme oxygenase-1 in cardiovascular homeostasis.2004
- Author(s)
  Ohta K, Yachie A
- Journal Title
  
  J Endovasc Ther 11 Suppl 2:II
  
  Pages: 140-150
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591014
[Journal Article] Long-term follow-up of a case of hypomagnesemia with secondary hypocalcemia caused by novel TRPM6 mutation
- Author(s)
  Shimizu, M., Niida, Y., Koizumi, S., Yachie, A.
- Journal Title
  
  Pediatric Nephrology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] 家族性地中海熱の精密医療の実現への試み2019
- Author(s)
  川上純，遠藤友志郎，古賀智裕，田中義正，右田清志，吉浦孝一郎，佐藤俊太朗，上松一永，谷内江明宏，増本純也，浦野健
- Organizer
  第40回日本炎症・再生医学会(神戸)
- Data Source
  KAKENHI-PROJECT-17H04656
[Presentation] Effect of Ginger Powder Extracts on Actin Assembly In Vitro2018
- Author(s)
  Naotoshi Sugimoto, Masanori Katakura, Kentaro Matsuzaki, Mayumi Miyamoto, Eri Sumiyoshi, Akihiro Yachie, Osamu Shido
- Organizer
  EXPERIMENTAL BIOLOGY 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01963
[Presentation] A THEOBROMINE-CONTAINING DIET STIMULATES CENTRAL CREB/BDNF PATHWAYS AND MOTOR LEARNING IN YOUNG MICE2018
- Author(s)
  Naotoshi Sugimoto, Mitsugu Yoneda, Masanori Katakura, Kentaro Matsuzaki, Hayate Tanigami, Yuki Tabata, Takako Ohno-Shosaku, Osamu Shido, Akihiro Yachie
- Organizer
  The 14th Asian Pan - Pacific Society of Pediatric Gastroenterology, Hepatology and Nutrition Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01963
[Presentation] Quantitative evaluation of mRNA expression of MEFV gene product pyrin in human tissues2018
- Author(s)
  Nakano N, Kaneko N, Kurata N, Yamamoto T, Urano T, Koga T, Kawakami A, Yachie A, Agematsu K, Migita K, Yoshiura K, Ishii E, Masumoto J.
- Organizer
  European Society for Immunodeficiencies 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04656
[Presentation] Hypoxia downregulates cannabinoid receptors, upregulates COX-2, and attenuates cannabinoid receptor agonist-induced cell death in glioblastoma cells2018
- Author(s)
  Naotoshi Sugimoto, Akihiro Yachie, Takako Ohno-Shosaku
- Organizer
  8th International Congress of Pathophysiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01963
[Presentation] Ginger powder extract prevents heat shock-induced cell death in mouse fibroblast cells2018
- Author(s)
  Naotoshi Sugimoto, Masanori Katakura, Kentaro Matsuzaki, Mayumi Miyamoto, Eri Sumiyoshi, Akihiro Yachie, Osamu Shido
- Organizer
  Pharmacology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01963
[Presentation] Theobromine crosses the blood brain barrier resulting in increased phosphorylation of vasodilator-stimulated phosphoprotein and cAMP-response element-binding protein in the mouse brain2017
- Author(s)
  Sugimoto N, Katakura M, Matsuzaki K, Yoneda M, Sumiyoshi E, Ohno-Shosaku T, Yachie A, Shido O.
- Organizer
  FFC’s 21st International Conference “Functional Foods and Bioactive Compounds in Health and Gisease: Science and Practice”
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2017-03-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282021
[Presentation] 全身型若年性特発性関節炎における NK 細胞の IL-18 不応答性の経時的検討2017
- Author(s)
  高倉麻衣子、清水正樹、井上なつみ、水田麻雄、清水陽、犀川太、川野充弘、谷内江昭宏
- Organizer
  第27回日本小児リウマチ学会
- Data Source
  KAKENHI-PROJECT-15H04873
[Presentation] Lipopolysaccharide increases the expression level of the aquaporin-4 water channel.2017
- Author(s)
  Sugimoto N, Nishimura N, Ohnishi N, Matsumoto T, Kitaura T, Shido O, Yachie A.
- Organizer
  Experimental Biology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01963
[Presentation] Ginger Powder Extracts activate MAP kinases in mouse fibroblast cells2017
- Author(s)
  Naotoshi Sugimoto, Masanori Katakura, Kentaro Matsuzaki, Mayumi Miyamoto, Eri Sumiyoshi, Akihiro Yachie, Osamu Shido
- Organizer
  British Pharmacological Society 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01963
[Presentation] Lipopolysaccharide increases the expression level of the aquaporin-4 water channel.2017
- Author(s)
  Sugimoto N, Nishimura N, Ohnishi N, Matsumoto T, Kitaura T, Shido O, Yachie A.
- Organizer
  Experimental Biology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13013
[Presentation] 全身型若年性特発性関節炎に合併するマクロファージ活性化症候群における soluble TNFR-II/I 比の臨床的有用性2017
- Author(s)
  井上なつみ、清水正樹、水田麻雄、谷内江昭宏、中岸保夫
- Organizer
  第27回日本小児リウマチ学会
- Data Source
  KAKENHI-PROJECT-15H04873
[Presentation] 全身型若年性特発性関節炎における急性炎症反応評価のための血清 Leucine-rich a 2-glycoprotein 値の臨床的有用性2017
- Author(s)
  清水正樹、作村直人、伊良部仁、高倉麻衣子、井上なつみ、水田麻雄、田崎優子、中岸保夫、金田尚、太田和秀、谷内江昭宏
- Organizer
  第27回日本小児リウマチ学会
- Data Source
  KAKENHI-PROJECT-15H04873
[Presentation] In vitro解析から見えてきた志賀毒素による中枢神経症状出現のメカニズム2016
- Author(s)
  杉本直俊、Lue Hue、清水正樹、東馬智子、黒田文人、和田泰三、谷内江昭宏
- Organizer
  第48回日本小児感染症学会　総会・学術集会
- Place of Presentation
  岡山県岡山市
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16K13013
[Presentation] Theobromine crosses the blood brain barrier in vivo resulting in increased phosphorylation of vasodilator-stimulated phosphoprotein in the mouse brain2016
- Author(s)
  Sugimoto N, Katakura M, Matsuzaki K, Ohno-Shosaku T, Yachie A, Shido O.
- Organizer
  Physiology 2016
- Place of Presentation
  Dublin, Ireland
- Year and Date
  2016-07-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282021
[Presentation] Theobromine, the primary methylxanthine found in Theobroma cacao, can pass through the blood-brain barrier in mice2016
- Author(s)
  Sugimoto N, Katakura M, Matsuzaki K, Ohno-Shosaku T, Yachie A, Shido O.
- Organizer
  Experimental Biology 2016 (EB2016)
- Place of Presentation
  San Diego, CA, USA.
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282021
[Presentation] Protective role of host mast cells against acute graft-versus-host disease2013
- Author(s)
  Araki,R., Nishimura, R., Maeba, H., Kuroda, R., Fujii, T., Mase, S., Koizumi, S., Yachie, A.
- Organizer
  55th Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans (USA)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] IFN-gamma-mediated elimination of host DCs by cytokine induced killer cells leads to less GVHD2013
- Author(s)
  Mase,S., Nishimura, R., Kuroda, R., Fujii,T., Araki, R., Maeba, H., Koizumi, S., Yachie, A.
- Organizer
  55th Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans (USA)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] 家族性地中海熱におけるサイトカインプロファイルと炎症病態2013
- Author(s)
  谷内江昭宏
- Organizer
  第6回自己炎症疾患研究会
- Place of Presentation
  ベルサール八重洲(東京都)
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] Monitoring of CD4+ T-cell receptor repertoire helps manage the patients with prolonged GVHD2013
- Author(s)
  Kuroda, R., Nishimura, R., Mase, S., Fujii, T., Araki, R., Maeba, H., Koizumi, S., Yachie, A.
- Organizer
  55th Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Evaluating Prolonged Gvhd Based On Monocyte and T-Cell Activation, Leads to Early Detection of Immunological Changes Before Gvhd Exacerbations2012
- Author(s)
  Rie Kuroda, Toshihiro Fujiki, Shintaro Mase, Raita Araki, Hideaki Maeba, Shoichi Koizumi, Akihiro Yachie, and Ryosei Nishimura
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Allogeneic cytokine-induced killer cells kill dendritic cells efficiently resulting in less graft-versus-host disease2012
- Author(s)
  Shintaro Mase, Rie Kuroda, Hideaki Maeba, Raita Araki, Toshihiro Fujiki, Shoichi Koizumi, Akihiro Yachie and Ryosei Nishimura
- Organizer
  38th Annual meeting of the European group for blood and marrow transplantation
- Place of Presentation
  Geneva, Switzerland
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Regulatory Role of Host IL-17 Via Control of Host Macrophage Activation Contributes to Less Acute Gvhd2012
- Author(s)
  Rie Kuroda, Katsuaki Sato, Hideaki Maeba, Toshihiro Fujiki, Shintaro Mase, Raita Araki, Kazuhito Naka, Makoto Naito, Yoichiro Iwakura, Akihiro Yachie, Shoichi Koizumi, and Ryosei Nishimur
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Heme oxygenase-1 deficiency : a novel autoinflammatory disease, associated with systemic inflammation, accelerated tissue injury and endothelial dysfunction2012
- Author(s)
  Yachie, A., Yokoyama, T., Shimizu, M., Ohta, K., Toma, T., Wada, T., Radhakrishnan, N., Sachdeva, A., Yadav, S.P.
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID 2012)
- Place of Presentation
  Florence Convention Center (Italy)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] MEFV変異を有する周期性発熱症候群におけるサイトカインプロファイルの特徴2012
- Author(s)
  東馬智子, 上野和之, 清水正樹, 谷内江昭宏
- Organizer
  第22回小児リウマチ学会
- Place of Presentation
  ウィルあいち(愛知県)
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] 末梢血リンパ球、単球活性化同時解析を用いた移植後病態解析；血便症例を例にあげて2012
- Author(s)
  黒田梨絵、西村良成、馬瀬新太郎、前馬秀昭、荒木来太、藤木俊寛、谷内江昭宏
- Organizer
  第５４回日本小児血液・がん学会
- Place of Presentation
  パシフィコ横浜会議センター
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] 培養肥満細胞を用いたGVHD治療への基礎的検討2012
- Author(s)
  荒木来太、西村良成、前馬秀昭、黒田梨絵、藤木俊寛、馬瀬新太郎、谷内江昭宏
- Organizer
  第５４回日本小児血液・がん学会
- Place of Presentation
  パシフィコ横浜会議センター
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Only High Concentration of Immunoglobulin Inhibits Activation of Lymphocytes: Potential Use of Immunoglobulin for Preventing Gvhd2012
- Author(s)
  Hideaki Maeba, Rie Kuroda, Toshihiro Hujiki, Shintaro Mase, Raita Araki, Shoichi Koizumi, Akihiro Yachie, and Ryosei Nishimura
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Potent strategy for treatment of GVHD utilizing cultured mast cells.2012
- Author(s)
  Araki R, Nishimura R, Maeba H, Fijiki T, Masae S, Kuroda R, Yachie A
- Organizer
  第７４回日本血液学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Superior Immunomodulatory Effects of Cultured Mast Cells: Potent Strategy for Treatment of Gvhd2012
- Author(s)
  Raita Araki, Hideaki Maeba, Rie Kuroda, Toshihiro Fujiki, Shintaro Mase, Shoichi Koizumi, Akihiro Yachie, and Ryosei Nishimura
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Allogeneic cytokine-induced killer cells kill dendritic cells efficiently resulting in less graft-versus-host disease2012
- Author(s)
  Mase,S., Kuroda,R., Maeba,H., Araki,R., Fujiki,T., Koizumi,S., Yachie,A., Nishimura,R.
- Organizer
  38th Annual meeting of the European group for blood and marrow transplantation (EBMT)
- Place of Presentation
  Geneva Convention Center (Switzerland)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Allogeneic Cytokine-Induced Killer Cell-Dependent Eimination of Host Dendritic Cells Leads to Less Graft-Versus-Host Disease.2012
- Author(s)
  Shintaro Mase, Hideaki Maeba, Toshihiro Fujiki, Rie Kuroda, Raita Araki, Shoichi Koizumi, Akihiro Yachie, and Ryosei Nishimura
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] A genetic variation in the heme oxygenase-1 gene predicts the outcome of HLA-fully-matched unrelated bone marrow transplantation2011
- Author(s)
  Morishita,E., Maruyama,K., Takami,A., Onizuka,M., Kawase,T., Morishima,Y., Fukuda,T., Kodera,Y., Ohtake,S., Yachie,A., Nakao,S.
- Organizer
  53rd Annual Meeting of American Society of Hematology
- Place of Presentation
  San Diego Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Pathogenesis of EB V-associated T/NK cell lymphoproliferative diseases2011
- Author(s)
  谷内江昭宏
- Organizer
  2011 International Pediatric Respiratory Forum and Update Course
- Place of Presentation
  Beijing International Convention Center (China)(招待講演)
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-21591353
[Presentation] PFAPA 症例におけるMEFV遺伝子変異の検索とその臨床的意義2011
- Author(s)
  東馬智子, 和田泰三, 清水正樹, 千田裕美,谷内江昭宏
- Organizer
  第21回日本小児リウマチ学会総会・学術集会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] Attempting to Classify Prolonged Graft-Versus-Host-Disease According to Monocyte Activation Status in Addition to T-Cell2011
- Author(s)
  ie Kuroda, Hideaki Maeba, Shintaro Mase, Raita Araki, Toshihiro Fujiki, Shoichi Koizumi, Akihiro Yachie, Ryosei Nishimura
- Organizer
  54th Annual Meeting of the American Society of Hematology (ASH)
- Place of Presentation
  San Diego Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] PFAPA症候群におけるMEFV遺伝子変異プロフィールの解析2011
- Author(s)
  東馬智子, 谷内江昭宏
- Organizer
  第61回日本アレルギー学会秋季学術集会
- Place of Presentation
  グランドプリンスホテル新高輪国際館パミール(東京都)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] Carbon monoxide releasing molecule-derived CORM egulates tissue factor, plasminogen activator inhibitor type 1, and thrombomodulin production by human endothelial cells2011
- Author(s)
  Maruyama K, Morishita E, Ohtake S, Yachie A, Nakao S
- Organizer
  52nd American Society of Hematology Annual Meeting
- Place of Presentation
  Orange Convention Center(USA)
- Data Source
  KAKENHI-PROJECT-21590613
[Presentation] Both Tissue-Derived and Bone Marrow-Derived Host IL-17 Producing Cells Are Required for Preventing Acute Graft-Versus-Host Disease2011
- Author(s)
  Rie Kuroda, Hideaki Maeba, Katsuaki Sato, Kazuhito Naka, Shintaro Mase, Raita Araki, Toshihiro Fujiki, Yoichiro Iwakura, Akihiro Yachie, Shoichi Koizumi, Ryosei Nishimura
- Organizer
  54th Annual Meeting of the American Society of Hematology (ASH)
- Place of Presentation
  San Diego Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Only Dendritic Cells, but Not Lymphocytes, Acquired Tolerogenicity by PUVA-Treatment by Upregulation of Indoleamine 2,3-Dioxygenase (IDO)2011
- Author(s)
  Hideaki Maeba, Rie Kuroda, Yo Niida, Shintaro Mase, Raita Araki, Toshihiro Fujiki, Akihiro Yachie, Shoichi Koizumi, Ryosei Nishimura
- Organizer
  54th Annual Meeting of the American Society of Hematology (ASH)
- Place of Presentation
  San Diego Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] Role of Il-17 Varies at Different Periods After Hematopoietic Stem Cell Transplantation : Protection From Acute Graft-Versus-Host Disease and Exacerbation of Chronic Graft-Versus-Host Disease.2010
- Author(s)
  Rie Kuroda, Ryosei Nishimura, Katsuaki Sato, Hideaki Maeba, Kazuhito Naka, Shintaro Mase, Raita Araki, Yasuhiro Ikawa, Yoichiro Iwakura, Shoichi Koizumi, Akihiro Yachie
- Organizer
  53rd annual meeting of the American Society of Hematology.
- Place of Presentation
  San Diego Convention Center, USA
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Liver-infiltrating CTL clone expands with the development of hepatitis-associated aplastic anemia.2010
- Author(s)
  Ryosei Nishimura, Rie Kuroda, Yasuhiro Ikawa, Shintaro Mase, Raita Araki, Hideaki Maeba, Masaki Shimizu, Yasuhiro Ikawa, Taizo Wada, Tomoko Toma, Shoichi Koizumi, Akihiro Yachie
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Potent Strategy for Treatmet of Gvhd and Autoimmune-Diseased by Infusion of Donor-Typed or Even Third-Party Tolerogenic Dendritic Cells by Psoralen Plus UVA Treatment.2010
- Author(s)
  Hideaki Maeba, Ryosei Nishimura, Rie Kuroda, Raita Araki, Shintaro Mase, Yasuhiro Ikawa, Akihiro Yachie, Shoichi Koizumi
- Organizer
  53rd annual meeting of the American Society of Hematology.
- Place of Presentation
  San Diego Convention Center, USA
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Cytokine-Induced Killer Cells Facilitate Immune Reconstitution After Allogeneic BMT in Mice.2010
- Author(s)
  Shintaro Mase, Ryosei Nishimura, Yasuhiro Ikawa, Rie Kuroda, Raita Araki, Hideaki Maeba, Masaki Shimizu, Taizo Wada, Tomoko Toma, Shoichi Koizumi, Akihiro Yachie
- Organizer
  53rd annual meeting ofthe American Society of Hematology(ASH)
- Place of Presentation
  San Diego Convention Center(USA)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] 当科で解析したMEFV遺伝子異常Exon 2 splice異常を特徴とする2家系を中心にした話題2010
- Author(s)
  谷内江昭宏
- Organizer
  平成22年度厚生労働科学研究費補助金難知性疾患克服研究事業「家族性地中海熱の病態解明と治療指針の確立」研究班第1回半会議
- Place of Presentation
  都市センターホテル(東京)
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] 制御性樹状細胞を用いた新たな造血幹細胞移植療法にむけて(現状とその問題点について)2010
- Author(s)
  前馬秀昭, 西村良成, 黒田梨絵, 馬瀬新太郎, 荒木来太, 小泉晶一, 谷内江昭宏
- Organizer
  第32回日本造血細胞移植学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] 再再発鼻腔原発NKリンパ腫に対する非血縁間同種骨髄移植後に多発骨壊死を来たした小児例2010
- Author(s)
  馬瀬新太郎, 西村良成, 前馬秀昭, 黒田梨絵, 荒木来太, 小泉晶一, 谷内江昭宏
- Organizer
  第32回日本造血細胞移植学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Characterization of EBV-infected CD8^+T cells in EBV-associated hemophagocytic lymphohistiocytosis2010
- Author(s)
  Wada T, Toga A, Sakakibara Y, Toma T, Yanagisawa R, Kanegane H, Yachie A
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-21591353
[Presentation] Cytokine-Induced Killer Cells Facilitate Immune Reconstitution After Allogeneic BMT In Mice.2010
- Author(s)
  Shintaro Mase, Ryosei Nishimura, Rie Kuroda, Hideaki Maeba, Kazuhito Naka, Raita Araki, Yasuhiro Ikawa , Shoichi Koizumi, Akihiro Yachie
- Organizer
  53rd annual meeting of the American Society of Hematology.
- Place of Presentation
  San Diego Convention Center, USA
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] EBVHLHの病態;早期診断・早期治療介入のためのサイトカインプロファイリングと細胞解析2010
- Author(s)
  谷内江昭宏
- Organizer
  第42回日本小児感染症学会教育講演
- Place of Presentation
  仙台国際センター(宮城県)
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21591353
[Presentation] 造血幹細胞移植後早期の末梢血CD69陽性HLA-DR陰性CD8細胞増加は正着不全の指標となりうる2010
- Author(s)
  黒田梨絵, 西村良成, 前馬秀昭, 馬瀬新太郎, 荒木来太, 小泉晶一, 谷内江昭宏
- Organizer
  第32回日本造血細胞移植学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Expansion of Liver-Infiltrating CTL Clone in Concert with the Development of Hepatitis-Associated Aplastic Anemia.2010
- Author(s)
  Yasuhiro Ikawa, Ryosei Nishimura, Shintaro Mase, Rie Kuroda, RaitaAraki, Hideaki Maeba, Masaki Shimizu, Taizo Wada, Tomoko Toma, Shoichi Koizumi, Akihiro Yachie
- Organizer
  53rd annual meeting ofthe American Society of Hematology(ASH)
- Place of Presentation
  San Diego Convention Center(USA)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] 当科で解析したMEFV遺伝子異常Exon 2 splice異常を特徴とする2家系を中心にした話題。MEFV遺伝子異常症にみられる多彩な臨床症状2010
- Author(s)
  谷内江昭宏, 刀祢裕美, 和田泰三, 東馬智子
- Organizer
  第22回北陸腸内細菌研究会
- Place of Presentation
  金沢大学(石川県)
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] Cytokine-induced killer.cells facilitate immune reconstitution after allogeneic BMT inmice.2010
- Author(s)
  Shintaro Mase, Ryosei Nishimura, Hideaki Maeba, Rie Kuroda, Raita Araki, Shoichi Koizumi, Akihiro Yachie
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Increased subpopulation of CD8^+T cells with CD5 down-regulation in familial hemophagocytic lymphohistiocytosis type 22010
- Author(s)
  Wada T, Sakakibara Y, Shimizu M, Nishimura R, Toma T, Ueno Y, Horita S, Yasumi T, Ohara O, Yachie A
- Organizer
  XIVth Meeting of the European Society for Immunodeficiencies
- Place of Presentation
  Istanbul Lutfi Kirdar Convention and Exhibition Centre(Turkey)
- Data Source
  KAKENHI-PROJECT-21591353
[Presentation] Differential expression of activation and homing molecules predict GVHD severity in affected organs.2010
- Author(s)
  Rie Kuroda, Ryosei Nishimura, Yasuhiro Ikawa, Shintaro Mase, Raita Araki, Hideaki Maeba, Kazuhiro Naka, Yasuhiro Ikawa, Shoichi Koizumi, Akihiro Yachie
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] New treatment strategy for GVHD by infusion of donor-typed PLTVA-treatedtolerogenic dendritic cells.2010
- Author(s)
  Hideaki Maeba, Ryosei Nishimura, Rie Kuroda, Yasuhiro Ikawa, Sliintaro Mase, Raita Araki, Yasuhiro Ikawa, Shoichi Koizumi, Akihiro Yachie
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] 家族性地中海熱ならびに疑い症例におけるMEFV遺伝子変異プロフィールの解析2010
- Author(s)
  東馬智子, 榊原康久, 刀祢裕美, 和田泰三, 谷内江昭宏
- Organizer
  第22回日本アレルギー学会春季臨床大会
- Place of Presentation
  京都府
- Year and Date
  2010-05-08
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] Curcumin down-regulates cytokine-mediated tissue factor and plasminogen activator type 1 expression in human endothelial cells2010
- Author(s)
  Morishita E, Maruyama K, Asakura H, Ohtake S, Yachie A, Nakao S
- Organizer
  52nd American Society of Hematology Annual Meeting
- Place of Presentation
  Orange Convention Center(USA)
- Data Source
  KAKENHI-PROJECT-21590613
[Presentation] Role of I1-17 Varies at Different Periods After Hematopoietic Stem Cell Transplantation : Protection From Acute Graft-Versus-Host Disease and Exacerbation of Chronic Graft-Versus-Host Disease.2010
- Author(s)
  Rie Kuroda, Ryosei Nishimura, Yasuhiro Ikawa, Shintaro Mase, Raita Araki, Hideaki Maeba, Masaki Shimizu, Taizo Wada, Tomoko Toma, Shoichi Koizumi, Akihiro Yachie
- Organizer
  53rd annual meeting ofthe American Society of Hematology(ASH)
- Place of Presentation
  San Diego Convention Center(USA)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] I-131MIBG内照射併用自家末梢血幹細胞移植を施行したMYCN増幅Stage4の1歳神経芽細胞腫初発例2010
- Author(s)
  荒木来太, 西村良成, 前馬秀昭, 黒田梨絵, 馬瀬新太郎, 小泉晶一, 谷内江昭宏
- Organizer
  第32回日本造血細胞移植学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Clinical significance of CD5 downregulation in Epstein Barr virus(EBV)-infected CD8^+T lymphocytes in EBV-associated hemophagocytic lymphohistiocytosis2010
- Author(s)
  Wada T, Toga A, Sakakibara Y, Toma T, Yanagisawa R, Kanegane H, Yachie A
- Organizer
  14^th International Congress of Immunology
- Place of Presentation
  神戸ポートピアホテル、神戸国際展示場(兵庫県)
- Data Source
  KAKENHI-PROJECT-21591353
[Presentation] Expansion of Liver-Infiltrating CTL Clone In Concert with the Development of Hepatitis-Associated AA.2010
- Author(s)
  Yasuhiro Ikawa, Ryosei Nishimura, Shintaro Mase, Rie Kuroda, Raita Araki, Hideaki Maeba, Masaki Shimizu, Taizo Wada, Tomoko Toma, Shoichi Koizumi, Akihiro Yachie
- Organizer
  53rd annual meeting of the American Society of Hematology.
- Place of Presentation
  San Diego Convention Center, USA
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Urinary heme oxygenase-1 is a novelbiomarker for an inflammatory tubulointerstitialdamage in acute kidney injury2010
- Author(s)
  Yokoyama T, Ohta K, Shimizu M, YachieA
- Organizer
  15^<th> Congress of the International Pediatric Nephrology Association
- Place of Presentation
  New York
- Year and Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-21591413
[Presentation] HO-1欠損と無脾症;第2例目のHO-1欠損症とその病態2009
- Author(s)
  谷内江昭宏、和田泰三、清水正樹、横山忠史、東馬智子、Radhakrishnan N、SachdevaA
- Organizer
  第6回Heme Oxygenase研究フォーラム
- Place of Presentation
  Kyoto
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-21591413
[Presentation] Strong Inhibition of Alloreaction by Newly Generated Tolerogenic Dendritic Cells by Psoralen Plus UVA Treatment.2009
- Author(s)
  Maeba H, Nishimura R, Kuroda R, Araki R, Mase S, Ikawa Y, Yachie A, Koizumi S.
- Organizer
  52nd annual meeting of the American Society of Hematology.
- Place of Presentation
  New Orleans Convention Center, USA
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] The diagnostic significance ofinterleukin-18 in patients with systemicjuvenile idiopathic arthritispredisposing to macrophage activationsyndrome2009
- Author(s)
  Shimizu M, Yokoyama T, Kaneda H, WadaT, Toma T, Ohta K, Kasahara Y, Yachie A
- Organizer
  The 9^<th> World Congress on Inflammation
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-21591413
[Presentation] The diagnostic significance of interleukin-18 in patients with systemic juvenile idiopathic arthritis predisposing to macrophage activation syndrome2009
- Author(s)
  Shimizu M, Yokoyama T, Kaneda H, WadaT, Toma T, Ohta K, Kasahara Y, Yachie A.
- Organizer
  The 9^th World Congress on Inflammation
- Place of Presentation
  Keio PlazaHotel(東京都)
- Data Source
  KAKENHI-PROJECT-21591353
[Presentation] Promoter DNA methylation of CD10 in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene.2009
- Author(s)
  Y.Ikawa, N.Sugimoto, S.Koizumi, A.Yachie, Y.Saikawa
- Organizer
  2009 annual meeting of the American Society of Clinical Oncology
- Place of Presentation
  Orlando Convention Center, USA
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Strong Inhibition of Alloreaction by Newly Generated Tolerogenic Dendritic Cells by Psoralen Plus UVA Treatment2009
- Author(s)
  Maeba H, Nishimura R, Kuroda R, Araki R, Mase S, Ikawa Y, Yachie A., Koizumi S.
- Organizer
  51st ASH Annual Meeting (アメリカ血液学会)
- Place of Presentation
  ニューオルリンズ、アメリカ合衆国
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] 免疫寛容を誘導する制御性樹状細胞の大量培養の確立とGVHD制御の応用に向けて2009
- Author(s)
  前馬秀明, 西村良成, 黒田理恵, 馬瀬新太郎, 谷内江昭宏, 小泉晶一
- Organizer
  第25回日本小児がん学会、第51回日本小児血液学会
- Place of Presentation
  東京、東京ベイホテル東急
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Dense Methylation Patterns of CD10 Promoters in CD 10-Negative Infant Acute Lymphoblastic Leukemia (ALL) with Mixed-Lineage Leukemia (MLL) Gene Rearrangements2009
- Author(s)
  Yasuhiro Ikawa, Naotoshi Sugimoto, Shintaro Mase, Rie Kuroda, Raita Araki^1 Ryosei Nishimura, Toru Horisawa, Naoki Okada, Shoichi Koizumi, Akihiro Yachie, Yutaka Saikawa
- Organizer
  100th annual meeting of the American Association of Cancer Research
- Place of Presentation
  Denver Convention Center, USA
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] 種痘様水泡症で気付かれた慢性活動性EBウイルス感染症(CAEBV)の4歳女児例2008
- Author(s)
  栂暁子, 馬瀬新太郎, 刀祢裕美, 清水正樹, 和田泰三, 東馬智子, 犀川太, 笠原善仁, 谷内江昭宏, 小泉品一, 長谷川稔, 全陽, 中田聡子
- Organizer
  第293回日本小児科学会北陸地方会
- Place of Presentation
  福井県吉田郡
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] ヘム分解の異常と疾患2008
- Author(s)
  谷内江昭宏
- Organizer
  第81回日本生化学会大会, 第31回日本分子生物学会年会同時開催
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] Multiple reversion mosaicism of common gamma chain(γc)mutation causing X-linked severe combined immunodeficiency restored enough T-cell repertoires to mount anti-varicella immunity. (Kawai T, Saitoh M, Nishikomari R : Pediatrics, Graduate School of Medicin, Kyoto University, Kyoto Japan), (Okafuji I : Kobe City Medical Center General Hospital, Kobe, Japan), (Sakai H, Murata Y, Tanaka N, Tanaka T, Ohmori K), (Murakami T : Pediatrics, Nara City Hospital, Nara, Japan), (Mori y : Laboratory of Virology and Vaccinology, National Institute of Biomedical innovation, Ibaraki, Japan), (Imai K : Pediatrics, National Defense Medical College Hospital, Tokorozawa, Japan)2008
- Author(s)
  Wada T, Yachie A, Heike T, Nakahara T
- Organizer
  13th Meeting of the European Society for Immunodeficiencies(ESID)
- Place of Presentation
  's-Hertogenbosch The Netherlands
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] クルクミンによるHO-1産生誘導と炎症制御2008
- Author(s)
  谷内江昭宏, 柴田文恵, 和田泰三, 金兼千春, 東馬智子
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] 小児腎尿路疾患における尿中hemeoxygenase-1の発現とバイオマーカープロファイリング2008
- Author(s)
  清水正樹, 横山忠史, 太田和秀, 谷内江昭宏
- Organizer
  第36回日本臨床免疫学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] Omenn症候群なちびに類似疾患の遺伝子異常と特徴的病態の発症機構2008
- Author(s)
  谷内江昭宏, 他
- Organizer
  第20回日本アレルギー学会春季臨床大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] ヘム分解の異常と疾患2008
- Author(s)
  谷内江昭宏
- Organizer
  第81回日本生化学会大会, 第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] 少量抗原摂取により誘発されたfood protein-induced enterocolitis syndrome(FPIES)の一例2008
- Author(s)
  栂暁子, 柴田文恵, 和田泰三, 金兼千春, 東馬智子, 谷内江昭宏
- Organizer
  第45回日本小児アレルギー学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] Omenn症候群ならびに類似疾患の遺伝子異常と特徴的病態の発症機構2008
- Author(s)
  谷内江昭宏, 柴田文恵, 和田泰三, 金兼千春, 東馬智子, 笠原善仁, 小泉晶一
- Organizer
  第20回日本アレルギー学会春季臨床大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] Donor Bone Marrow Derived IL-17 Expressing Cells Exacerbate Chronic Graft-Versus-Host Disease in a Murine Bone Marrow Transplantation2008
- Author(s)
  Rie Kuroda, Ryosei Nishimura, Katsuaki Sato, Hideaki Maeba, Kazuhito Naka, Yo Niida, Raita Araki, Yoichiro Iwakura, Shoichi Koizumi, Akihiro Yachie
- Organizer
  51st annual meeting of the American Society of Hematology.
- Place of Presentation
  San Francisco Convention Center, USA
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] 急性EBV感染を契機に発症した全身型若年性特発性関節炎の1例2008
- Author(s)
  横山忠史, 伊川泰広, 和田泰三, 東馬智子, 笠原善仁, 谷内江昭宏, 長沖優子, 和田英男
- Organizer
  第111回日本小児科学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] Donor bone marrow derived IL-17 expressing cells exacerbate chronic graft-versus-host disease in a murine bone marrow transplantation.2008
- Author(s)
  Kuroda R, Nishimura R, Sato K, Maeba H, Naka K, Niida Y, Araki R, Iwakura Y, Koizumi S, Yachie A
- Organizer
  American Society of Hematology
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] 慢性活動性EBウイルス感染症男児例における蚊刺後の水疱内細胞成分の解析2008
- Author(s)
  和田泰三, 柴田文恵, 中川裕康, 橋田暢子, 刀祢裕美, 清水正樹, 東馬智子, 笠原善仁, 谷内江昭宏
- Organizer
  第16回北陸ウイルス感染症研究会
- Place of Presentation
  金沢
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] 病原性大腸菌O157による出血性大腸炎に続発した劇症型抗リン脂質抗体症候群(CAPS)の一例2008
- Author(s)
  清水正樹, 谷内江昭宏, 太田和秀
- Organizer
  第18回日本小児リウマチ学会総会・学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] 各種腎尿路系疾患における尿沈渣中hemeoxygenase-1の発現~尿中バイオマーカーから炎症性腎疾患の病態を把握する試み~2008
- Author(s)
  横山忠史, 清水正樹, 谷内江昭宏, 小泉晶一, (太田和秀 : 金沢医療センター小児科)
- Organizer
  第43回日本小児腎臓病学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] Omenn症候群様症状を呈した非典型的X-SCIDにみられた遺伝子変異の復帰2008
- Author(s)
  和田泰三, 東馬智子, 刀祢裕美, 笠原善仁, 小泉晶一, 谷内江昭宏, 安井昌博, 井上雅美
- Organizer
  第111回日本小児科学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] Omenn Disease and Related Syndrome ; Variable Genetic Backgrounds and Common Pathogenesis2008
- Author(s)
  Yachie A
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19591244
[Presentation] The first case of human HO-1 deficiency; its clinical profiles as a disease of immune dysregulation.2007
- Author(s)
  Yachie A
- Organizer
  The 5th International Congress Heme Oxygenase 2007
- Place of Presentation
  Krakow, Poland
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Presentation] The first case of human HO-1 deficiency ; its clinical profiles as a disease of immune dysregulation2007
- Author(s)
  Yachie, A
- Organizer
  The 5th International Congress Heme Oxygenase
- Place of Presentation
  Krakow, Poland
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590523
[Presentation] PUVA-treated dendritic cells have strong tolerogenic function by upregulation of IDO.
- Author(s)
  Maeba H, Kuroda R, Niida Y, Araki R, Mase S, Fujiki T, Koizumi S, Yachie A, Nishimura R
- Organizer
  第７３回日本血液学会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] 家族性地中海熱症例の長期臨床経過と血清サイトカイン
- Author(s)
  谷内江　昭宏
- Organizer
  厚生労働省難治性疾患克服研究事業「家族性地中海熱の病態解明と治療指針の確立」班　平成24年度　班会議
- Place of Presentation
  都市センターホテル（東京）
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] Theobromine, the primary methylxanthine found in Theobroma cacao, inhibits malignant glioblastoma cell growth by negatively regulating Akt/mammalian target of rapamycin kinase.
- Author(s)
  Sugimoto N, Miwa S, Katakura M, Matsuzaki K, Shido O, Tsuchiya H, Yachie A.
- Organizer
  EB2014
- Place of Presentation
  San Diego Convention Center, San Diego, CA, USA
- Year and Date
  2014-04-26 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-25282021
[Presentation] Attempting to classify prolonge GVHD according to monocyte activation status in addition to T-cell.
- Author(s)
  Kuroda R, Nishimura R, Maeba H, Araki R, Mase S, Fujiki T, Koizumi S, Yachie A
- Organizer
  第７３回日本血液学会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] The effect of exposure to mild heat stress on culture cells.
- Author(s)
  Sugimoto N, Matsuzaki K, Katakura M, Yachie A, Shido O.
- Organizer
  EB2015
- Place of Presentation
  Boston Convention Center, Boston, MA, USA
- Year and Date
  2015-03-27 – 2015-04-01
- Data Source
  KAKENHI-PROJECT-25282021
[Presentation] 志賀毒素のグリア細胞への作用、2011年に発生した焼肉屋チェーン店食中毒の事例から予測されること（第2報）
- Author(s)
  杉本直俊、東馬智子、清水正樹、黒田文人、和田泰三、谷内江昭宏
- Organizer
  第9回スフィンゴテラピィ研究会
- Place of Presentation
  山中温泉河鹿荘ロイヤルホテル（石川県加賀市）
- Year and Date
  2014-07-18 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-25282021
[Presentation] 家族性地中海熱におけるサイトカインプロファイルと炎症病態
- Author(s)
  谷内江　昭宏
- Organizer
  第６回自己炎症疾患研究会
- Place of Presentation
  ベルサール八重洲（東京）
- Data Source
  KAKENHI-PROJECT-22591152
[Presentation] Distinct role of IL-17 after HSCT: Protection from acute GVHD, while exacerbation of chronic GVHD.
- Author(s)
  Kuroda R, Maeba H, Sato K, Naka K, Araki R, Mase S, Fujiki T, Iwakura Y, Koizumi S, Yachie A, Nishimura R.
- Organizer
  第７３回日本血液学会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23591531
[Presentation] 全身性若年性特発性関節炎におけるHO-1の役割とバイオマーカーとしての有用性
- Author(s)
  清水正樹、谷内江昭宏
- Organizer
  第８回HO研究フォーラムKyoto
- Place of Presentation
  京都府立医科大学青蓮会館（京都府）
- Data Source
  KAKENHI-PROJECT-23591531

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yachie akihiro 谷内江 昭宏

YACHIE Akihiro 谷内江 昭宏

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新生児ヘモクロマトーシスの原因となるアロ抗体同定とIVIG治療の理論的基盤の確立Principal Investigator

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Identification of allo-specific antibody responsible for the pathogenesis of neonatal hemochromatosisPrincipal Investigator

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Omics-based analysis of molecular pathogenesis of systemic juvenile idiopathic arthritis and development of novel therapeutic interventionPrincipal Investigator

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Establishment of novel diagnostic parameters for the early therapeutic intervention of EBV-associated lymphoproliferative diseases.Principal Investigator

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yachie akihiro 谷内江昭宏

YACHIE Akihiro 谷内江昭宏