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KUMAGAI Yuji  熊谷 雄治

ORCIDConnect your ORCID iD *help
Researcher Number 40215017
Other IDs
Affiliation (based on the past Project Information) *help 2011: 北里大学, 医学部, 教授
2008 – 2011: Kitasato University, 医学部, 准教授
Review Section/Research Field
Principal Investigator
General pharmacology
Except Principal Investigator
Psychiatric science / Medical pharmacy
Keywords
Principal Investigator
CD34 / Fibrocyte / コラーゲン / スポンジ / C57B16マウス / TPシグナリング / トロンボキサン / スポンジモデル / 血小板 / TXA2 … More / PGE2 / fibrocyte / CD34陽性 / 線維化 / 血管新生 / マトリゲル … More
Except Principal Investigator
代謝 / 自律神経機能 / 認知機能 / 薬理学 / 脳・神経 / 生活習慣病 / 睡眠生理学 / 睡眠薬 / 精神薬理学 / MATE / OAT / 腎スライス / トランスポーター / 薬剤感受性 / atorvastatin / 肝クリアランス / CYP3A4 / 律速段階 / 体内動態 / OATP / MATEs / シメチジン / ヒト腎スライス / ヒト肝細胞 / 薬物間相互作用 / フェノタイピング / クリアランスの律速段階 / 薬物トランスポーター / プローブ薬 Less
  • Research Projects

    (3 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (9 People)
  •  Effects on metabolism and cognitive functions by hypnotics induced slow wave sleep modulation in healthy young male volunteers

    • Principal Investigator
      TAGAYA Hirokuni
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Kitasato University
  •  Development of probe drugs for the evaluation of the functions of drug transporters in vivo in humans

    • Principal Investigator
      SUGIYAMA Yuichi
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Medical pharmacy
    • Research Institution
      The University of Tokyo
  •  血小板凝集時に放出されるSDFー1による骨髄細胞動員増強作用と臓器線維化の誘導Principal Investigator

    • Principal Investigator
      熊谷 雄治
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Kitasato University

All 2010 2009 2008

All Journal Article Presentation Book

  • [Book] First in man試験の革新2010

    • Author(s)
      熊谷雄治
    • Total Pages
      5
    • Publisher
      メディカルドウ
    • Data Source
      KAKENHI-PROJECT-20659038
  • [Journal Article] Estimating the contribution of genes to variation in renal drug clearance by active secretion using multiple data from clinical phase I studies.2010

    • Author(s)
      Fujita T, Kumagai Y, Nakahara I, Ohtani Y, Majima M.
    • Journal Title

      J Clin Pharmacol.

      Volume: 50 Pages: 109-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659038
  • [Journal Article] Safety, Tolerability and Pharmacokinetics of TAS-108, a Novel Anti-Oestrogen, in Healthy Post-Menopausal Japanese Women2009

    • Author(s)
      Kumagai Y, 他8名
    • Journal Title

      Basic Clin Pharmacol Toxicol. (In presss)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659038
  • [Journal Article] Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model.2008

    • Author(s)
      Kumagai Y, 他6名
    • Journal Title

      J Pharmacol Exp Ther. 327

      Pages: 592-599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659038
  • [Presentation] 初期臨床試験のあり方2009

    • Author(s)
      熊谷雄治
    • Organizer
      第15回医学統計研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-08-02
    • Data Source
      KAKENHI-PROJECT-20659038
  • [Presentation] SEARCH AND VALIDATION OF IN VIVO PROBE DRUGS FOR FUNCTIONAL ANALYSIS OF OAT1 AND OAT3 IN HUMANS2008

    • Author(s)
      Tian Y, Maeda K, Kumagai Y, Kondo T, Kusuhara H and Sugiyama Y
    • Organizer
      日本薬物動態学会第23回年会
    • Place of Presentation
      熊本
    • Year and Date
      2008-11-01
    • Data Source
      KAKENHI-PROJECT-20249008
  • 1.  SUGIYAMA Yuichi (80090471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  KUSUHARA Hiroyuki (00302612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  MAEDA Kazuya (00345258)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  HAYASHI Hisamitsu (10451858)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SUWA Toshio (20383664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TAGAYA Hirokuni (50342928)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  川村 道子 (00154104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  天野 英樹 (60296481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  馬嶋 正隆 (70181641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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