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nakamura minoru  中村 稔

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NAKAMURA Minoru  中村 稔

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Researcher Number 40217906
External Links
Affiliation (Current) 2025: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 臨床研究センター, 客員研究員
Affiliation (based on the past Project Information) *help 2014 – 2023: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 臨床研究センター, 客員研究員
2017: 長崎医療センター, 臨床研究センター, 客員研究員
2013: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), その他部局等, 客員研究員
2013: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), その他部局等, 研究員
2011 – 2012: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 臨床研究センター, 客員研究員 … More
2010: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 長崎医療センター・臨床研究センター, 客員研究員
2010: Department of Clinical Research, National Hospital Organization Nagasaki Medical Center, 臨床研究センター, 客員研究員
2009: Department of Clinical Research, National Hospital Organization Nagasaki Medical Center, 客員研究員
2008: Department of Clinical Research, National Hospital Organization Nagasaki Medical Center, 長崎医療センター・臨床研究センター, 客員研究員
2006: Nagasaki Medical Center, Clinical Research Center, Director of the Department of Advanced Medical Research, 先端技術研究部, 部長
2006: 独立行政法人国立病院機構長崎医療センター臨床研究センター), 先端技術研究部, 部長
2006: Nagasaki Medical Center, Clinical Research Center, Morphological Department, Chief of Pathology Division, 臨床研究センター・先端技術研究部, 部長
2005: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 先端技術研究部長
2005: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 先端技術研究部, 先端技術研究部長
2005: Clinical Research Center, Nagasaki Medical Center, 臨床研究センター, 先端技術研究部長
2004: National Hospital Organization Nagasaki Medical Center, Clinical Research Center, Department of Advanced Medical Research, Director, 長崎医療センター・臨床研究センター, 先端技術研究部長
2004: National Hospital Organization Nagasaki Medical Center, Clinical Research Center, Division of Advanced Medical Research, Director, 長崎医療センター・臨床研究センター, 先端技術研究部長
2004: 独立行政法人国立病院機構長崎医療センター, 臨床研究センター, 先端技術研究部長
2003: 国立病院, 長崎医療センター・臨床研究センター, 先端技術研究部長
2003: 国立病院長崎医療センター(臨床研究センター), 先端技術研究部長
2003: 国立病院長崎医療センター, 臨床研究センター, 先端技術研究部長
2000 – 2001: 九州大学, 医学部・附属病院, 助手
1999: 九州大学, 大学院・医学系研究科, 助手
1989 – 1999: 九州大学, 医学部, 助手
1992: Kyushu Univ.Fac.Med.Assist.Prof., 歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
内科学一般 / Gastroenterology / Basic Section 53010:Gastroenterology-related / 膠原病・アレルギー・感染症内科学
Except Principal Investigator
内科学一般 / Gastroenterology / Basic Section 53010:Gastroenterology-related / Medical genome science / Human pathology / General surgery / 内分泌・代謝学
Keywords
Principal Investigator
原発性胆汁性肝硬変 / 分子標的 / 疾患感受性遺伝子 / primary biliary cirrhosis / 抗ミトコンドリア抗体 / ゲノムワイド関連解析 / 原発性胆汁性胆管炎 / 抗gp210抗体 / HTLV-1 / 統合解析 … More / トランスクリプトーム / NHOSLJ / laser microdissection / p16INK4a / TAKA-1 / 疾患発症経路 / 肝臓学 / GWAS / 抗セントロメア抗体 / 病型分類 / 予後予測 / CXCケモカイン / 膜融合 / T細胞エピトープ / 中和エピトープ / ペプチドワクチン / 治療標的 / 臨床ゲノム解析 / 疾患関連遺伝子 / ネガティブフィードバック機構 / IFNG / PTPN2 / 網羅的遺伝子発現解析 / anti-nuclear antibodies / anti-mitochondrial antibodies / predictive autoantibodies / anti-centromere antibodies / anti-gp210 antibodies / 自然免疫 / 胆管上皮細胞 / TLR3 / centromere / gp210 / 抗核抗体 / 予後予測抗体 / gene expression / anti-gp210 antibody / prognostic marker / etiology-associated antigen / chronic hepatitis C / autoimmune hepatitis / 遺伝子発現 / 予後予測因子 / 病因関連抗原 / 慢性C型肝炎 / 自己免疫性肝炎 / apoptosis / differentiation / adherent cell line / floating cell line / demethylation adenocarcinoma / poorly differentiated / DNAメチレーション / 腺癌 / アポトーシス / 分化 / 付着細胞株 / 浮遊細胞株 / 脱メチル化 / 未分化腺癌細胞株 / mitochondrial antigen / analogue peptide / molecular mimicry / PDC-E2 / antigen-specific immunotherapy / immune-regulation / autoimmune disease / 自己免疫疾患 / 分子相同性 / ペプチド複合体 / MHC / 原発性胆汁性肝研変 / 免疫応答 / アナログペプチド / ミトコンドリア抗原 / 抗原特異的治療法 / 免疫制御 / 自己免疫性疾患 / REPORTER GENE ACTIVATION ASSAY / VSV-PSEUDOTYPE / HTLV-I RECEPTOR / CXC CHEMOKINE / HTLV-I / MEMBRANE FUSION / HTLV-1 レセプター / 膜 融合 / reporter gene activation assay / HTLV-1レセプター / VSV-pseudotype / anti-mitochondrial antibody / T cell epitope / B cell epitope / peptide based vaccine / neutralizing epitope / anti-HTLV-1 antibody / human monoclonal antibody / B lymphocyte repertoire / T-cell エピトープ / B cell エピトープ / 抗HTLV-I抗体 / T Cell エピトープ / B Cell エピトープ / 抗HTLV-1 抗体 / T-cellエピトープ / B cellエピトープ / 抗HTLV-1抗体 / ヒト型モノクローナル抗体 / Bリンパ球レパートリー / 疾患発症パスウェイ / 予後予測マーカー / 全ゲノム関連解析 / 長期予後診断 / 非黄疸型進行 / 黄疸型進行 / バイオマーカー / 予後 / HLA-DRB1 / 一塩基多型(SNP) / HLA / 遺伝子多型 / SNPs / 感染防御 / CTLエピトープ / B細胞エピトープ … More
Except Principal Investigator
原発性胆汁性肝硬変 / ゲノムワイド関連解析 / 自己免疫性疾患 / シグナル伝達 / 原発性胆汁性胆管炎 / 免疫応答 / molecular mimicry / T細胞エピトープ / HLA / Ras / Rho / Rac / 自己抗体 / 抗ミトコンドリア抗体 / 足場依存性喪失 / rho / rac / アポトーシス / T細胞 / 癌遺伝子 / 疾患感受性遺伝子 / トランスクリプトーム解析 / PBC / Src / ミトコンドリア抗原 / 自己反応性T細胞 / apoptosis / Immune response / Molecular mimicry / T cell epitope / T cell / Autoimmune disease / Primary biliary cirrhosis / 自己免疫 / autoantibody / Bリンパ球 / ras / Srcチロシンキナーゼ / Focal Adhesion Kinase / がん遺伝子 / 免疫制御 / チロシンキナーゼ / サイトカイン / 増殖制御 / 癌細胞 / GWAS / PRKCB / Replication Study / 機能解析 / Imputtaion / ヒト白血球抗原(HLA) / 層別化解析(悪性化) / ゲノムワイド関連解析(GWAS) / 原発性胆汁性胆管炎(PBC) / 国際共同研究 / 層別化解析 / replication study / 遺伝要因探索 / 病態模倣培養系 / 脂質メディエーター / 免疫学 / GWA / 網羅的資質解析 / 網羅的遺伝子解析 / 疾患模倣培養系 / 脂質情報 / 網羅的アレイ解析 / 免疫細胞 / 胆管細胞 / 肝臓学 / カテプシン / epidemiology / Chernobyl / radiation / childhood / thyroid cancer / 分子疫学 / 放射線発癌 / BRAF / PTC / RET / 甲状腺癌 / 放射線 / チェルノブイリ / Gene transfer / Hepatocyte transplantation / Bioartificial liver / Bank of hepatocytes / Human hepatocyte / 肝不全 / ヒト肝細胞化マウス / 凍結保存 / 人畜共通感染症 / キメラマウス / 遺伝子導入 / 肝細胞移植 / 人工肝臓 / 肝細胞バンク / ヒト肝細胞 / IFN Receptor / IFN Management / IFN Signal / Chronic Hepatitis C / IFNレセプター / IFN治療 / IFNシグナル / C型慢性肝炎 / anti-mitochondrial antibody / prediction of prognosis / anti-gp210 antibody / Toll-like receptor (TLR) / innate immunity / biliary epithelial cells / bile duct damage / primary biliary cirrhosis / 病因関連抗原 / CD8陽性T細胞 / ミトコンドリア抗体 / 予後予測因子 / 抗原特異的T細胞 / PPARα / 予後予測マーカー / 抗gp210抗体 / Toll-like受容体 / 自然免疫 / 胆管上皮細胞 / 胆管障害 / invasion / Drug resistance / signal transduction / Tyrosine kinase / Srcがん遺伝子 / Bcl-2 / 浸潤能 / 抗がん剤耐性 / anti-mitochondria antibody / autoantigen / analogue peptide / auto-reactive T cell / autoimmune / Primary Biliary Cirrhosis / MHC複合体 / ペプチド / 自己抗原 / アナログペプチド / 分子相同性 / Src tyrosine kinase / loss of anchorage-dependence / Focal adhesion kinase / signal transductione / Oncogene / T cell receptor / Immune regulation / T細胞レセプター / Immunoglobulin gene / エピトープ / 免疫グロブリン遺伝子 / autoimmunity / immunoglobulin subclass / anti-Phospholipid Ab / Glutamic acid Decarboxylase / B lymphocytes / insulitis / NOD mouse / diabetes / インスリン / GAD / Glutamic Acid docarboxylase / 免疫グロブリンサブクラス / 抗リン脂質抗体 / Glutamic Acid Decarboxylase / 膵島炎 / NODマウス / 糖尿病 / 2-oxoglutarate dehydrogenase complex, OGDC / pyruvate dehydrogenase complex, PDC / autoimmune disease / antibody production / B lymphocyte / anti-mitochondrial antibody, AMA / primary biliary cirrhosis, PBC / 2ーオキソグルタル酸脱水素酵素複合体 / 2-オキソグルタル酸脱水素酵素複合体 / ピルビン酸脱水素酵素複合体 / 抗体産生異常 / 原発性胆汁性肝硬変症 / 肝細胞癌 / 哺乳類細胞発現ベクター / DNA修復機構関連蛋白 / 肝発癌機構 / 遺伝子クローニング / DNA修復酵素 / HCVコア蛋白 / C型肝炎ウイルス / srcチロジンキナーゼ / アポートーシス / DNA修復機構 / シスプラチン / 抗癌剤耐性 / チロシン・キナーゼ / c-kal / 造腫瘍性 / Bリンパ腫 / 腫瘍抑制遺伝子 / p53 / 癌抑制遺伝子 / TGIF / 密度阻止 / 癌増殖抑制因子 / V79癌細胞 / 腫瘍増殖制御因子 / 腫瘍抑制因子 Less
  • Research Projects

    (36 results)
  • Research Products

    (377 results)
  • Co-Researchers

    (49 People)
  •  原発性胆汁性胆管炎の新たな病態解明と治療標的の同定を目指した臨床ゲノム解析Principal Investigator

    • Principal Investigator
      中村 稔
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Analysis of POU2AF1 and its related molecules in the portal tract of primary biliary cholangitis

    • Principal Investigator
      相葉 佳洋
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Analysis of PRKCB in primary biliary cholangitis based on integration analysis data

    • Principal Investigator
      AIBA YOSHIHIRO
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  The role of cathepsin Z for liver failure-type progression in primary biliary cholangitis

    • Principal Investigator
      AIBA YOSHIHIRO
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Development of new treatment methods for primary biliary cholangitis by genome and lipid information from disease mimic culture system

    • Principal Investigator
      Shimoda Shinji
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyushu University
  •  GWAS-based integrated analysis of PBC to dissect the mechanism of development and progression of primary biliary cholangitisPrincipal Investigator

    • Principal Investigator
      Nakamura Minoru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Searching for the genetic factors predisposing to PBC

    • Principal Investigator
      KAWASHIMA Minae
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical genome science
    • Research Institution
      The University of Tokyo
  •  Analysis of disease-pathways and molecular targets by disease-susceptibility genes in primary biliary cholangitisPrincipal Investigator

    • Principal Investigator
      Nakamura Minoru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Genome-wide associationstudy to detect disease-associated genes in Japanese patients with primary biliary cirrhosisPrincipal Investigator

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  New clinical classification and the criteria for predicting long-term outcome in primary biliary cirrhosisPrincipal Investigator

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Molecular epidemiology of radiation induced thyroid cancer

    • Principal Investigator
      ITO Masahiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      National Hospital Organization Nagasaki Medical Center
  •  Identification of new molecular targets and the study for the mechanism of bile ducts-and hepatocyte-destruction in primary biliary cirrhosisPrincipal Investigator

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Hospital Organization(NHO) Nagasaki Medical Center
  •  C型肝炎ウイルスコア蛋白と結合するDNA修復酵素の遺伝子クローニング

    • Principal Investigator
      石橋 大海
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Dissection of autoimmune response and establishment of diagnosis and treatment of primary biliary cirrhosis

    • Principal Investigator
      ISHIBASHI Hiromi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Clinical Research Center National Hospital Organization (NHO) Nagasaki Medical Center
  •  Single nucleotide polymorphisms in interferon signaling pathway and immuno system response to interferon treatment in hepatitis C patients

    • Principal Investigator
      YATSUHASHI Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Hospital Organization Nagasaki Medical Center, Clinical Research Center
  •  Construction of antibody-library to identify etiology-associated-antigenPrincipal Investigator

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      National Hospital Organization Nagasaki Medical Center, Clinical Research Center
  •  Clinical application of bioartifical liver support and heopatocyte transplantation using human hepatocytes

    • Principal Investigator
      FUJIOKA Hikaru
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      National Hospital Organization Nagasaki Medical Center Clinical Research Center
  •  Gene cloning of the novel molecules associated with the differentiation of adenocarcinoma and the development of the molecular target therapyPrincipal Investigator

    • Principal Investigator
      MITSUGI Kenji, 中村 稔
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu Uni versity
  •  MECHANISTIC STUDY OF THE ROLE OF TYROSINE KINASE SIGNAL

    • Principal Investigator
      NAKANO Shuji
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  The analysis of epitope and immunological response of primary biliary cirrhosis

    • Principal Investigator
      HAYASHIDA Kazuhiro, 石橋 大海
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Identification and characterization of T cell epitope in primary biliary cirrhosisPrincipal Investigator

    • Principal Investigator
      NAKAMURA Minoru, 石橋 大海
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  MECHANISTIC STUDY OF APOPTOTIC CELL DEATH AND INVASION POTENTIAL USING SIGNAL TRANSDUCTION INHIBITORS IN THE ONCOGENE-TRANSFECTED HUMAN CELLS

    • Principal Investigator
      NAKANO Shuji
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  FUNCTIONAL AND DNA ALALYSIS OF THE NOVEL PROTEIN (R21 PROTEIN) INVOLVED IN MEMBRANE FUSIONPrincipal Investigator

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  新しい膜融合蛋白の精製および遺伝子クローニングPrincipal Investigator

    • Principal Investigator
      中村 稔
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  癌遺伝子導入ヒト細胞を使用したシグナル伝達制御による抗癌剤感受性の解析

    • Principal Investigator
      中野 修治
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  原発性胆汁性肝硬変の病因エピトープの同定と抗原特異的治療法の開発

    • Principal Investigator
      ISHIBASHI Hiromi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  がん遺伝子導入ヒト上皮細胞の癌化とアポトーシスにおけるシグナル伝達機構の解析

    • Principal Investigator
      中野 修治
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  MOLECULAR MECHANISM OF IMMUNE REGULATION IN PRIMARY BILIARY CIRRHOSIS

    • Principal Investigator
      ISHIBASHI Hiromi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  高度造腫瘍性を有するヒトBリンパ腫細胞の癌化と増殖制御の遺伝子レベルでの解析

    • Principal Investigator
      中野 修治
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  HTLV-1に対するペプチドワクチンの開発Principal Investigator

    • Principal Investigator
      中村 稔
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  ANALYSIS OF IMMUNE RESPONSE IN PRIMARY BILIARY CIRRHOSIS

    • Principal Investigator
      ISHIBASHI Hiromi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Identification of HTLV-1 neutralizing epitopes and the development of an HTLV-1 peptide based vaccinePrincipal Investigator

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  腫瘍由来増殖抑制因子の作用メカニズムと一次構造の解析

    • Principal Investigator
      中野 修治
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  Analysis of Anti-mitochondrial Antibody Producing B Cell Repertoire in Primary Biliary Cirrhosis

    • Principal Investigator
      ISHIBASHI Hiromi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Functional analysis of infiltrating lymphocytes to islets in NOD mic

    • Principal Investigator
      NAGAFUCHI Seiho
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      KYUSHU UNIVERSITY
  •  腫瘍由来増殖制御因子による癌増殖制御の解析

    • Principal Investigator
      NAKANO Shuji
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Other

  • [Book] 日本臨床2020

    • Author(s)
      中村 稔
    • Total Pages
      11
    • Publisher
      日本臨床社
    • ISBN
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Book] 原発性胆汁性肝硬変. 今日の治療指針 2018年版2017

    • Author(s)
      中村 稔
    • Total Pages
      2192
    • Publisher
      医学書院
    • ISBN
      9784260032339
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Book] 2017 今日の治療指針2017

    • Author(s)
      中村 稔
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Book] Autoimmune Liver Diseases: Perspectives from Japan. edited Hiromasa Ohira.2014

    • Author(s)
      Nakamura M.
    • Total Pages
      306
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Book] 分子消化器病2014

    • Author(s)
      千葉 勉、松坂 恵介、高橋 佑典、柴田 龍弘、津田 喬之、中村 稔、金井 弥栄、角田 洋一、服部 正平ほか
    • Total Pages
      108
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Book] Hepatology practiceシリーズ 第4巻 難治性疾患の診療を極める~基本から最前線まで~2014

    • Author(s)
      大平弘正、坂井田功、中村 稔
    • Total Pages
      342
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Book] ゲノムワイド関連解析による日本人原発性胆汁性肝硬変の疾患感受性遺伝子、TNFSF15、POU2AF1の同定分子消化器病2013

    • Author(s)
      中村稔
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Book] PBCの疾患感受性遺伝子による病態の解明2012

    • Author(s)
      中村稔
    • Publisher
      C.I.Research
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Book] PBCの疾患感受性遺伝子による病態の解明.特集:ゲノムワイド関連解析からみえてきた消化器疾患2012

    • Author(s)
      中村稔
    • Publisher
      G.I.Research
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Book] PBCの疾患感受性遺伝子による病態の解明2012

    • Author(s)
      中村 稔
    • Total Pages
      6
    • Publisher
      先端医学社 C.I.Research vol 20
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Book] 遺伝子多型は自己免疫性肝胆道疾患の病態にせまれるか分子消化器病2011

    • Author(s)
      中村稔、石橋大海
    • Publisher
      先端医学社 (発行者 : 鯨岡哲)
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Book] 原発性胆汁性肝硬変(PBC)の診療ガイド2011

    • Author(s)
      坪内博仁、中沼安二、石橋大海、調憲、中村稔、田中篤, 他
    • Total Pages
      56
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Book] HLADRB1遺伝子多型が降格抗体による原発性胆汁性肝硬変の予後予測に及ぼす影響の検討,消化器と免疫N046, 20092010

    • Author(s)
      中村稔、安波道郎、近藤久義、相葉佳洋、小森敦正、長岡進矢、阿比留正剛、八橋弘、右田清志、石橋大海
    • Publisher
      マイライフ社
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Book] 核膜康複合体タンパク質Gp210生体の科学細胞核-構造と機能2010

    • Author(s)
      中村稔、相葉佳洋
    • Publisher
      (財)金原一郎記念医学医療振興財団
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Book] 原発性胆汁性肝硬変(PBC)の診療ガイド(厚生労働省"難治性の肝・胆道疾患に関する調査研究"班編)2010

    • Author(s)
      坪内博仁、中沼安二、石橋大海、上野義之、上本伸二、江川裕人、向坂彰太郎、國土典宏、下田慎治、滝川一、中牟田誠、西原利治、廣原淳子、前原喜彦、松崎靖司、宮川浩、調憲、田中篤、中村稔
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Book] 日本人原発性胆汁性肝硬変患者(PBC)のCTLA4一塩基多型(SNP)の解析.消化器と免疫N046, 20092010

    • Author(s)
      相葉佳洋、小森敦正、右田清志、八橋弘、塚元和弘、石橋大海、中村稔
    • Publisher
      マイライフ社
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Book] 原発性胆汁性肝硬変の病因と予後,第4章:非ウイルス性肝障害,肝疾患Review 2008-20092008

    • Author(s)
      石橋大海, 中村稔, 下田慎治
    • Publisher
      日本メディカルセンター
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Book] 免疫学的機序-原発性胆汁性肝硬変の病態と免疫機序, PBC, PSCと肝移植<第4回伊豆肝臓カンファレンス記録>(市田隆文編)2008

    • Author(s)
      石橋大海, 下田慎治, 中村稔
    • Publisher
      アークメディア,東京
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Book] Annual Review消化器 : 原発性胆汁性肝硬変 (PBC)2007

    • Author(s)
      石橋大海, 小森敦正, 中村 稔
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Book] Annual Review 消化器:原発性胆汁性肝硬変(PBC)2007

    • Author(s)
      石橋大海, 小森敦正, 中村 稔
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Book] 肝臓病の最新治療(戸田剛太郎,沖田極,門田守人,井廻道夫,幕内雅敏,恩地森一,森正樹,茶山一彰,持田智,銭谷幹男編集)2006

    • Author(s)
      石橋大海, 下田慎治, 中村稔
    • Total Pages
      406
    • Publisher
      先端医療技術研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Book] 肝疾患と免疫(各務伸一編)2006

    • Author(s)
      小森敦正, 中村稔, 石橋大海
    • Total Pages
      179
    • Publisher
      医薬ジャーナル社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Book] 肝疾患と免疫(各務伸一 編)2005

    • Author(s)
      小森敦正, 中村稔, 石橋大海
    • Publisher
      医歯薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Book] 臨床消化器内科 182003

    • Author(s)
      中村 稔, 下田慎治, 石橋大海
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] 自己免疫性肝疾患の遺伝因子2024

    • Author(s)
      中村 稔.
    • Journal Title

      Precision Medicine

      Volume: 6(14) Pages: 1136-1140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K07366
  • [Journal Article] rs10924104 in the expression enhancer motif of CD58 confers susceptibility to human autoimmune diseases2023

    • Author(s)
      Hitomi Yuki、Ueno Kazuko、Aiba Yoshihiro、Nishida Nao、Kawai Yosuke、Kawashima Minae、Khor Seik-Soon、Takada Sanami、Iwabuchi Chisato、Nagasaki Masao、Tokunaga Katsushi、Nakamura Minoru
    • Journal Title

      Human Genetics

      Volume: 143 Issue: 1 Pages: 19-33

    • DOI

      10.1007/s00439-023-02617-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08065, KAKENHI-PROJECT-23K07366, KAKENHI-PROJECT-23K07471
  • [Journal Article] Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population2023

    • Author(s)
      Khor Seik-Soon、Ueno Kazuko、Nishida Nao、Kawashima Minae、Kawai Yosuke、Aiba Yoshihiro、Hitomi Yuki、Nagasaki Masao、Nakamura Minoru、Tokunaga Katsushi
    • Journal Title

      Frontiers in Immunology

      Volume: 14 Pages: 1151502-1151502

    • DOI

      10.3389/fimmu.2023.1151502

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08065, KAKENHI-PROJECT-23K07366, KAKENHI-PROJECT-23K07471
  • [Journal Article] The Genetics of Primary Biliary Cholangitis: A GWAS and Post-GWAS Update.2023

    • Author(s)
      Hitomi Y, Nakamura M.
    • Journal Title

      Genes

      Volume: 14 Issue: 2 Pages: 405-405

    • DOI

      10.3390/genes14020405

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08065, KAKENHI-PROJECT-23K07366
  • [Journal Article] rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis2022

    • Author(s)
      Hitomi Yuki、Aiba Yoshihiro、Ueno Kazuko、Nishida Nao、Kawai Yosuke、Kawashima Minae、Yasunami Michio、Gervais Olivier、Ito Masahiro、Cordell Heather J.、Mells George F.、Nagasaki Masao、Tokunaga Katsushi、Tsuiji Makoto、Nakamura Minoru
    • Journal Title

      Journal of Autoimmunity

      Volume: 126 Pages: 102775-102775

    • DOI

      10.1016/j.jaut.2021.102775

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K07471, KAKENHI-PROJECT-19K08413, KAKENHI-PROJECT-20K08370
  • [Journal Article] Regional heritability mapping identifies several novel loci (STAT4, 3 ULK4, and KCNH5) for primary biliary cholangitis in the Japanese 4 population2021

    • Author(s)
      Olivier Gervais, Kazuko Ueno, Yosuke Kawai, Yuki Hitomi, Yoshihiro Aiba, Mayumi Ueta, Minoru Nakamura, Katsushi Tokunaga & Masao Nagasaki
    • Journal Title

      European Journal of Human Genetics

      Volume: - Issue: 8 Pages: 1282-1291

    • DOI

      10.1038/s41431-021-00854-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08370, KAKENHI-PROJECT-19K08413
  • [Journal Article] Association of soluble T cell immunoglobulin domain and mucin-3 (sTIM-3) and mac-2 binding protein glycosylation isomer (M2BPGi) in patients with autoimmune hepatitis2020

    • Author(s)
      Kiyoshi Migita ,Minoru Nakamura,Yoshihiro Aiba,Hideko Kozuru,Seigo Abiru,Atsumasa Komori,Yuya Fujita,Junpei Temmoku,Tomoyuki Asano,Shuzo Sato,Makiko Furuya,Atsushi Naganuma,Kaname Yoshizawa,Masaaki Shimada,Keisuke Ario,Tomohiko Mannami,Hiroshi Kohno,Toshihiko Kaneyoshi,Takuya Komura,Hiromasa Ohira,Hiroshi Yatsuhashi
    • Journal Title

      PLoS One

      Volume: - Issue: 12 Pages: e0238540-e0238540

    • DOI

      10.1371/journal.pone.0238540

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Journal Article] Role of deleterious single nucleotide variants in the coding regions of TNFAIP3 for Japanese autoimmune hepatitis with cirrhosis2019

    • Author(s)
      Higuchi T, Oka S, Furukawa H, Nakamura M, Komori A, Abiru S, Hashimoto S, Shimada M, Yoshizawa K, Kouno H, Naganuma A, Ario K, Kaneyoshi T, Yamashita H, Takahashi H, Makita F, Yatsuhashi H, Ohira H, Migita K.
    • Journal Title

      Sci Rep

      Volume: 9(1) Issue: 1 Pages: 7925-7925

    • DOI

      10.1038/s41598-019-44524-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] Galectin-9 in autoimmune hepatitis: Correlation between serum levels of galectin-9 and M2BPGi in patients with autoimmune hepatitis2019

    • Author(s)
      Matsuoka N, Kozuru H, Koga T, Abiru S, Yamasaki K, Komori A, Fujita Y, Tenmoku J, Asano T, Sato S, Suzuki E, Furuya M, Kobayashi H, Watanabe H, Naganuma A, Yoshizawa K, Shimada M, Ario K, Yamashita H, Kohno H, Kaneyoshi T, Nakamura M, Furukawa H, Takahashi A, Kawakami A, Ohira H, Yatsuhashi H, Migita K.
    • Journal Title

      Medicine (Baltimore)

      Volume: 98(35) Issue: 35 Pages: e16924-e16924

    • DOI

      10.1097/md.0000000000016924

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] 【ゲノムサイエンスの肝疾患診療への応用】 原発性胆汁性胆管炎(PBC)の疾患感受性遺伝子 - 臨床応用への展望 -2018

    • Author(s)
      中村 稔
    • Journal Title

      消化器・肝臓内科

      Volume: 3(1) Pages: 97-105

    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis2018

    • Author(s)
      Aiba Yoshihiro、Harada Kenichi、Ito Masahiro、Suematsu Takashi、Aishima Shinichi、Hitomi Yuki、Nishida Nao、Kawashima Minae、Takatsuki Mitsuhisa、Eguchi Susumu、Shimoda Shinji、Nakamura Hitomi、Komori Atsumasa、Abiru Seigo、Nagaoka Shinya、Migita Kiyoshi、Yatsuhashi Hiroshi、Tokunaga Katsushi、Nakamura Minoru
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 11808-11808

    • DOI

      10.1038/s41598-018-30146-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09449, KAKENHI-PROJECT-17K15924, KAKENHI-PROJECT-17H04169
  • [Journal Article] Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis2018

    • Author(s)
      Aiba Y, Harada K, Ito M, Suematsu T, Aishima S, Hitomi Y, Nishida N, Kawashima M, Takatsuki M, Eguchi S, Shimoda S, Nakamura H, Komori A, Abiru S, Nagaoka S, Migita K, Yatsuhashi H, Tokunaga K, Nakamura M
    • Journal Title

      Sci Rep

      Volume: 8(1) Pages: 11808-11808

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04164
  • [Journal Article] Nishida N, Aiba Y, Hitomi Y, Kawashima M, Kojima K, Kawai Y, Ueno K, Nakamura H, Yamashiki N, Tanaka T, Tamura S, Mori A, Yagi S, Soejima Y, Yoshizumi T, Takatsuki M, Tanaka A, Harada K, Shimoda S, Komori A, Eguchi S, Maehara Y, Uemoto S, Kokudo N, Nagasaki M, Tokunaga K, Nakamura M2018

    • Author(s)
      Nishida N, Aiba Y, Hitomi Y, Kawashima M, Kojima K, Kawai Y, Ueno K, Nakamura H, Yamashiki N, Tanaka T, Tamura S, Mori A, Yagi S, Soejima Y, Yoshizumi T, Takatsuki M, Tanaka A, Harada K, Shimoda S, Komori A, Eguchi S, Maehara Y, Uemoto S, Kokudo N, Nagasaki M, Tokunaga K, Nakamura M
    • Journal Title

      Sci Rep.

      Volume: 8(1) Pages: 8071-8071

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04164
  • [Journal Article] 【ゲノムサイエンスの肝疾患診療への応用】 原発性胆汁性胆管炎(PBC)の疾患感受性遺伝子 -臨床応用への展望-2018

    • Author(s)
      中村 稔
    • Journal Title

      消化器・肝臓内科

      Volume: 3(1) Pages: 97-105

    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] A Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn’s Disease in Japanese Individuals2018

    • Author(s)
      Kakuta Yoichi、Kawai Yosuke、Naito Takeo、Hirano Atsushi、Umeno Junji、Fuyuno Yuta、Liu Zhenqiu、Li Dalin、Nakano Takeru、Izumiyama Yasuhiro、Ichikawa Ryo、Okamoto Daisuke、et al.
    • Journal Title

      Journal of Crohn's and Colitis

      Volume: - Issue: 5 Pages: 2019-2019

    • DOI

      10.1093/ecco-jcc/jjy197

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-17H04169
  • [Journal Article] NFKB1 and MANBA Confer Disease Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants.2018

    • Author(s)
      Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
    • Journal Title

      Cell Mol Gastroenterol Hepatol

      Volume: 7 Issue: 3 Pages: 515-532

    • DOI

      10.1016/j.jcmgh.2018.11.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15924, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-17H04168, KAKENHI-PROJECT-17K09449
  • [Journal Article] Genome-wide haplotype association analysis of primary biliary cholangitis risk in Japanese.2018

    • Author(s)
      Im C, Sapkota Y, Moon W, Kawashima M, Nakamura M, Tokunaga K, Yasui Y.
    • Journal Title

      Sci Rep.

      Volume: 8(1) Issue: 1 Pages: 7806-7806

    • DOI

      10.1038/s41598-018-26112-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] Cathepsin Z variants are associated with progression to end-stage hepatic failure in Japanese patients with primary biliary cholangitis.2017

    • Author(s)
      Nishida N, Aiba Y, Kawashima M, Hitomi Y, Kojima K, Komori A, Nagasaki M,Tokunaga K, Nakamura M
    • Journal Title

      J Hepatol

      Volume: 66(1, Suppl)

    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] Principal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese population2017

    • Author(s)
      Yasunami Michio、Nakamura Hitomi、Tokunaga Katsushi、Kawashima Minae、Nishida Nao、Hitomi Yuki、Nakamura Minoru
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 11093-11093

    • DOI

      10.1038/s41598-017-11148-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15924, KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314
  • [Journal Article] Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.2017

    • Author(s)
      Kawashima M, et al, Shimoda S, et al, Nakamura M.
    • Journal Title

      Hum Mol Genet.

      Volume: 26 Pages: 650-659

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04164
  • [Journal Article] 【今日から役立つ肝胆膵疾患の遺伝子診断学】 これからの遺伝子診断を理解するためのOverview ここまでわかったPBCの疾患感受性遺伝子.2017

    • Author(s)
      中村 稔:
    • Journal Title

      肝・胆・膵

      Volume: 74(2) Pages: 279-289

    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] 【自己免疫性肝・胆管疾患のupdate】 自己免疫性肝・胆管疾患の病態 AIH、PBC、PSCの遺伝的背景 GWAS解析を中心に.2017

    • Author(s)
      中村 稔
    • Journal Title

      肝・胆・膵

      Volume: 74(6) Pages: 853-865

    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] ここまでわかったPBCの疾患感受性遺伝子2017

    • Author(s)
      中村 稔
    • Journal Title

      肝胆膵

      Volume: 74(2) Pages: 279-289

    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis2017

    • Author(s)
      Hitomi Yuki、Kojima Kaname、Kawashima Minae、Kawai Yosuke、Nishida Nao、Aiba Yoshihiro、Yasunami Michio、Nagasaki Masao、Nakamura Minoru、Tokunaga Katsushi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 2904-2904

    • DOI

      10.1038/s41598-017-03067-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-15K06908
  • [Journal Article] Association of a single nucleotide polymorphism upstream of ICOS with Japanese autoimmune hepatitis type 1.2017

    • Author(s)
      Higuchi T, Oka S, Furukawa H, Nakamura M, Komori A, Abiru S, Nagaoka S, Hashimoto S, Naganuma A, Naeshiro N, Yoshizawa K, Shimada M, Nishimura H, Tomizawa M, Kikuchi M, Makita F, Yamashita H, Ario K, Yatsuhashi H, Tohma S, Kawasaki A, Ohira H, Tsuchiya N, Migita K.
    • Journal Title

      J Hum Genet.

      Volume: in press Issue: 4 Pages: 481-484

    • DOI

      10.1038/jhg.2016.155

    • NAID

      40021158271

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293123, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-15K09543, KAKENHI-PROJECT-16K15154
  • [Journal Article] HLA-DRB1 and DQB1 alleles in Japanese type 1 autoimmune hepatitis: The predisposing role of the DR4/DR8 heterozygous genotype2017

    • Author(s)
      Oka Shomi、Furukawa Hiroshi、Yasunami Michio、他
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 10 Pages: e0187325-e0187325

    • DOI

      10.1371/journal.pone.0187325

    • NAID

      120007128808

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-15K09543, KAKENHI-PROJECT-16K15154
  • [Journal Article] 【原発性胆汁性胆管炎:病名変更後の動向】 原発性胆汁性胆管炎の成立機序 遺伝子の探索関連2017

    • Author(s)
      中村 稔
    • Journal Title

      消化器・肝臓内科

      Volume: 1(6) Pages: 635-643

    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Journal Article] Association between Anti-Ganglionic Nicotinic Acetylcholine Receptor (gAChR) Antibodies and HLA-DRB1 Alleles in the Japanese Population.2016

    • Author(s)
      Maeda Y, Migita K, Higuchi O, Mukaino A, Furukawa H, Komori A, Nakamura M, Hashimoto S, Nagaoka S, Abiru S, Yatsuhashi H, Matsuo H, Kawakami A, Yasunami M, Nakane S
    • Journal Title

      PLoS One

      Volume: 11 Issue: 1 Pages: e0146048-e0146048

    • DOI

      10.1371/journal.pone.0146048

    • NAID

      120007129614

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461305, KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-26293181
  • [Journal Article] Hepatic flares promote rapid decline of serum hepatitis B surface antigen (HBsAg) in patients with HBsAg seroclearance: A long-term follow-up study.2016

    • Author(s)
      Nagaoka S, Abiru S, Komori A, Sasaki R, Bekki S, Hashimoto S, Saeki A, Yamasaki K, Migita K, Nakamura M, Ezaki H, Yatsuhashi H.
    • Journal Title

      Hepatol Res.

      Volume: 46(3) Issue: 3

    • DOI

      10.1111/hepr.12533

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis.2016

    • Author(s)
      N. Nishida (他37名, 山本31番目)
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 24767-24767

    • DOI

      10.1038/srep24767

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-15K08986, KAKENHI-PROJECT-26293179, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-16K09387, KAKENHI-PROJECT-15K15483
  • [Journal Article] Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis.2016

    • Author(s)
      Hisamoto S, Shimoda S, Harada K, Iwasaka S, Onohara S, Chong Y, Nakamura M, Bekki Y, Yoshizumi T, Ikegami T, Maehara Y, He XS, Gershwin ME, Akashi K.
    • Journal Title

      J Autoimmun.

      Volume: 75 Pages: 150-160

    • DOI

      10.1016/j.jaut.2016.08.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26460416
  • [Journal Article] Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.2016

    • Author(s)
      Sun Y, Irwanto A, Toyo-Oka L, Hong M, Liu H, Andiappan AK, Choi H, Hitomi Y, Yu G, Yu Y, Bao F, Wang C, Fu X, Yue Z, Wang H, Zhang H, Kawashima M, Kojima K, Nagasaki M, Nakamura M, Yang SK, Ye BD, Denise Y, Rotzschke O, Song K, Tokunaga K, Zhang F, Liu J.
    • Journal Title

      Sci Rep.

      Volume: 10(6) Issue: 1 Pages: 31429-31429

    • DOI

      10.1038/srep31429

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314
  • [Journal Article] Rapid Increase in Serum Low-Density Lipoprotein Cholesterol Concentration during Hepatitis C Interferon-Free Treatment.2016

    • Author(s)
      Hashimoto S, Yatsuhashi H, Abiru S, Yamasaki K, Komori A, Nagaoka S, Saeki A, Uchida S, Bekki S, Kugiyama Y, Nagata K, Nakamura M, Migita K, Nakao K.
    • Journal Title

      PLoS One.

      Volume: 11(9) Issue: 9 Pages: e0163644-e0163644

    • DOI

      10.1371/journal.pone.0163644

    • NAID

      120006987625

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] Natural killer cells regulate T cell immune responses in primary biliary cirrhosis.2015

    • Author(s)
      Shimoda S, Hisamoto S, Harada K, Iwasaka S, Chong Y, Nakamura M, Bekki Y, Yoshizumi T, Shirabe K, Ikegami T, Maehara Y, He XS, Gershwin ME, Akashi K.
    • Journal Title

      Hepatology.

      Volume: 62 Issue: 6 Pages: 1817-1827

    • DOI

      10.1002/hep.28122

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10167, KAKENHI-PROJECT-26460416, KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-25253069, KAKENHI-PROJECT-26293181
  • [Journal Article] Disease susceptibility genes shared by primary biliary cirrhosis and Crohn’s disease in the Japanese population2015

    • Author(s)
      Yoshihiro Aiba, Keiko Yamazaki, Nao Nishida, Minae Kawashima, Yuki Hitomi, Hitomi Nakamura, Atsumasa Komori, Yuta Fuyuno, Atsushi Takahashi, Takaaki Kawaguchi, Masakazu Takazoe, Yasuo Suzuki, Satoshi Motoya Toshiyuki Matsui Motohiro Esaki, Takayuki Matsumoto, Michiaki Kubo, Katsushi Tokunaga, Minoru Nakamura
    • Journal Title

      Journal of Human Genetics

      Volume: 印刷中 Issue: 9 Pages: 525-531

    • DOI

      10.1038/jhg.2015.59

    • NAID

      40020589506

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25860576, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314, KAKENHI-PROJECT-15K19357, KAKENHI-PROJECT-26293180, KAKENHI-PROJECT-26293181
  • [Journal Article] Aberrant Expression of Keratin 7 in Hepatocytes as a Predictive Marker of Rapid Progression to Hepatic Failure in Asymptomatic Primary Biliary Cirrhosis.2015

    • Author(s)
      Seki H, Ikeda F, Nanba S, Moritou Y, Takeuchi Y, Yasunaka T, Onishi H, Miyake Y, Takaki A, Nouso K, Iwasaki Y, Nakamura M, Yamamoto K.
    • Journal Title

      Acta Med Okayama.

      Volume: 69(3) Pages: 137-144

    • NAID

      120005621907

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] Human primary biliary cirrhosis-susceptible allele of rs4979462 enhances TNFSF15 expression by binding NF-1.2015

    • Author(s)
      Hitomi Y, Kawashima M, Aiba Y, Nishida N, Matsuhashi M, Okazaki H, Nakamura M, Tokunaga K
    • Journal Title

      Human Genetics

      Volume: 印刷中 Issue: 7 Pages: 737-747

    • DOI

      10.1007/s00439-015-1556-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860576, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314, KAKENHI-PROJECT-15K19357, KAKENHI-PROJECT-26293181
  • [Journal Article] 原発性胆汁性肝硬変の発症や予後を予測できるか?2015

    • Author(s)
      中村 稔
    • Journal Title

      分子消化器病

      Volume: 12(1) Pages: 49-57

    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] CYP7A1遺伝子多型が影響する原発性胆汁性肝硬変進化メカニズムの解明.2015

    • Author(s)
      稲嶺達夫, 中村 稔, 塚元和弘
    • Journal Title

      臨床薬理の進歩

      Volume: 36 Pages: 91-99

    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] Genetic polymorphisms of OCT-1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients.2014

    • Author(s)
      Ohishi Y, Nakamuta M, Ishikawa N, Saitoh O, Nakamura H, Aiba Y, Komori A, Migita K, Yatsuhashi H, Fukushima N, Kohjima M, Yoshimoto T, Fukuizumi K, Ishibashi M, Nishino T, Shirabe K, Taketomi A, Maehara Y, Ishibashi H, Nakamura M; PBC Study Group of NHOSLJ.
    • Journal Title

      J Gastroenterol.

      Volume: 49 Issue: 2 Pages: 332-342

    • DOI

      10.1007/s00535-013-0795-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006, KAKENHI-PROJECT-26293181
  • [Journal Article] Clinical signigicance of autoantibodies in primary biliary cirrhosis.2014

    • Author(s)
      Nakamura M.
    • Journal Title

      Semin Liver Dis.

      Volume: 34 Pages: 334-340

    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] Analysis of disease-pathways by susceptibility genes in primary biliary cirrhosis.2014

    • Author(s)
      Nakamura M.
    • Journal Title

      Inflammation and Regeneration

      Volume: 134 Pages: 78-86

    • NAID

      10031195130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] STAT4 gene polymorphisms are associated with susceptibility and ANA status in primary biliary cirrhosis.2014

    • Author(s)
      Joshita S, Umemura T, Nakamura M, Katsuyama Y, Shibata S, Kimura T, Morita S, Komatsu M, Matsumoto A, Yoshizawa K, Ishibashi H, Tanaka E, Ota M.
    • Journal Title

      Disease Markers

      Volume: Epub Pages: 727393-727393

    • DOI

      10.1155/2014/727393

    • NAID

      120007107427

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590969, KAKENHI-PROJECT-23591006, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26460996
  • [Journal Article] Effects of Janus kinase inhibitor tofacitinib on circulating serum amyloid A and interleukin-6 during treatment for rheumatoid arthritis.2014

    • Author(s)
      Migita K1, Izumi Y, Jiuchi Y, Kozuru H, Kawahara C, Izumi M, Sakai T, Nakamura M, Motokawa S, Nakamura T, Kawakami A.
    • Journal Title

      Clin Exp Immunol.

      Volume: 175 Issue: 2 Pages: 208-214

    • DOI

      10.1111/cei.12234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591452, KAKENHI-PROJECT-26293181
  • [Journal Article] 日本人原発性胆汁性肝硬変の疾患感受性遺伝子の同定2014

    • Author(s)
      中村 稔
    • Journal Title

      細胞

      Volume: 46 Pages: 148-150

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] 日本人原発性胆汁性肝硬変の疾患感受性遺伝子の同定.2014

    • Author(s)
      中村 稔.
    • Journal Title

      細胞

      Volume: 46 Pages: 148-150

    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] Analysis of disease-pathways by susceptibility genes in primary biliary cirrhosis.2014

    • Author(s)
      Nakamura M.
    • Journal Title

      Inflammation and Regeneration

      Volume: 34 Pages: 78-86

    • NAID

      10031195130

    • Data Source
      KAKENHI-PROJECT-26293181
  • [Journal Article] STAT4 gene polymorphisms are associated with susceptibility and ANA status in primary biliary cirrhosis2014

    • Author(s)
      Joshita S, Umemura T, Nakamura M, Katsuyama Y, Shibata S, Kimura T, Morita S, Komatsu M, Matsumoto A, Yoshizawa K, Ishibashi H, Tanaka E, Ota M
    • Journal Title

      Dis Markers. 2014

      Volume: (Epub 2014 Feb 4.) Pages: 727393-727393

    • NAID

      120007107427

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Chronologic changes of explanted liver volume and the use of ursodeoxycholic acid in patients with end-stage primary biliary cirrhosis.2013

    • Author(s)
      Tanaka T, Yamashiki N, Sugawara Y, Tamura S, Nakamura M, Kaneko J, Aoki T, Sakamoto Y, Hasegawa K, Kokudo N.
    • Journal Title

      Hepatol Res.

      Volume: Dec 2 Issue: 9 Pages: 993-999

    • DOI

      10.1111/hepr.12283

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006, KAKENHI-PROJECT-24591867
  • [Journal Article] 原発性胆汁性肝硬変における血中Fractralkineの意義2013

    • Author(s)
      原田憲一、中村 稔、下田慎治、中沼安二
    • Journal Title

      消化器と免疫

      Volume: 49 Pages: 12-14

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] PBCの疾患感受性遺伝子による病態の解明2013

    • Author(s)
      中村稔
    • Journal Title

      日本消化器病学会雑誌

      Volume: 110 Pages: 1602-1610

    • NAID

      10031147894

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] 原発性胆汁性肝硬変(PBC)の疾患感受性遺伝子による病態の解明.2013

    • Author(s)
      中村 稔、西田奈央、川嶋実苗、相葉佳洋、小森敦正、八橋 弘、徳永勝士. 国立病院機構肝ネットワークPBC研究班、 厚生労働省難治性疾患克服研究事業・難治性の肝胆膵疾患に関する調査研究班.
    • Journal Title

      第20回浜名湖シンポジウム記録集 ゲノム情報の臨床応用

      Volume: なし Pages: 74-78

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Clinicopathological significance of serum fractalkine in primary biliary cirrhosis.2013

    • Author(s)
      Harada K, Kakuda Y, Nakamura M, Shimoda S, Nakanuma Y.
    • Journal Title

      Dig Dis Sci

      Volume: 58 Issue: 10 Pages: 3037-43

    • DOI

      10.1007/s10620-013-2734-6

    • NAID

      120005349179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590393, KAKENHI-PROJECT-23591006
  • [Journal Article] Chronologic changes of explanted liver volume and the use of ursodeoxycholic acid in patients with end-stage primary biliary cirrhosis2013

    • Author(s)
      Tanaka T, Yamashiki N, Sugawara Y, Tamura S, Nakamura M, Kaneko J, Aoki T, Sakamoto Y, Hasegawa K, Kokudo N
    • Journal Title

      Hepatol Res

      Volume: (Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] PBCの治療反応性と予後予測 ―厚生労働省研究班による多施設のPBC研究成果―2013

    • Author(s)
      中村 稔
    • Journal Title

      たんじゅうさん

      Volume: 12 Pages: 16-17

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] PBC Study Group of NHOSLJ, Nakamura M. Genetic polymorphisms of OCT-1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients2013

    • Author(s)
      Ohishi Y, Nakamuta M, Ishikawa N, Saitoh O, Nakamura H, Aiba Y, Komori K, Migita K, Yatsuhashi H, Fukushima N, Kohjima M, Yoshimoto T, Fukuizumi K, Ishibashi M, Nishino T, Shirabe K, Taketomi A, Maehara Y, Ishibashi H
    • Journal Title

      J Gastroenterol

      Volume: (Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Association of genes involved in bile acid synthesis with the progression of primary biliary cirrhosis in Japanese patients.2013

    • Author(s)
      Inamine T, Higa S, Noguchi F, Kondo S, Omagari K, Yatsuhashi H, Tsukamoto K, Nakamura M.
    • Journal Title

      J Gastroenterol.

      Volume: 48 Issue: 10 Pages: 1160-1170

    • DOI

      10.1007/s00535-012-0730-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Association of genes involved in bile acid synthesis with the progression of primary biliary cirrhosis in Japanese patients2013

    • Author(s)
      Inamine T, Higa S, Noguchi F, Kondo S, Omagari K, Yatsuhashi H, Tsukamoto K, Nakamura M
    • Journal Title

      J Gastroenterol

      Volume: (Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] The role of TL1A and DR3 in autoimmune and inflammatory diseases.2013

    • Author(s)
      Aiba Y , Nakamura M.
    • Journal Title

      Mediators of Inflammation

      Volume: 未 Pages: 258164-258164

    • DOI

      10.1155/2013/258164

    • NAID

      120006986697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006, KAKENHI-PROJECT-25860576
  • [Journal Article] PBC治療反応性と予後予測厚生労働省研究班による多施設のPBC研究成果2013

    • Author(s)
      中村稔
    • Journal Title

      たんじゅうさん

      Volume: 12(2) Pages: 16-17

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Clinicopathological significance of serum fractalkine in primary biliary cirrhosis2013

    • Author(s)
      Harada K, Kakuda Y, Nakamura M, Shimoda S, Nakanuma Y
    • Journal Title

      Dig Dis Sci

      Volume: (Epub ahead of print)

    • NAID

      120005349179

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] PBC最近の話題2013

    • Author(s)
      大平弘正、原田憲一、下田慎治、中村 稔
    • Journal Title

      日本消化器病学会雑誌

      Volume: 110 Pages: 29-43

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Genetic polymorphisms of OCT-1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients.2013

    • Author(s)
      Ohishi Y, Nakamuta M, Ishikawa N, Saitoh O, Nakamura H, et al
    • Journal Title

      J Gastroenterol.

      Volume: April 24 Epub ahead of print Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population.2013

    • Author(s)
      Migita K, Nakamura M, Abiru S, Jiuchi Y, Nagaoka S, Komori A, Hashimoto S, Bekki S, Yamasaki K, Komatsu T, Shimada M, Kouno H, Hijioka T, Kohjima M, Nakamuta M, Kato M, Yoshizawa K, Ohta H, Nakamura Y, Takezaki E, Nishimura H, Sato T, Ario K, Hirashima N,..., Yatsuhashi H, Ishibashi H, Yasunami M.
    • Journal Title

      PLoS One

      Volume: 22;8 Issue: 8 Pages: e71382-e71382

    • DOI

      10.1371/journal.pone.0071382

    • NAID

      120006986124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] The Role of TL1A and DR3 in autoimmune and inflammatory diseases2013

    • Author(s)
      Aiba Y and Nakamura M
    • Journal Title

      Mediators of Inflammation

      Volume: (258164)

    • NAID

      120006986697

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] 原発性胆汁性肝硬変の予後2013

    • Author(s)
      小森敦正、石橋大海、中村 稔、八橋 弘
    • Journal Title

      肝胆膵

      Volume: 66 Pages: 455-461

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] 【自己免疫疾患・アレルギー疾患(後篇)それぞれの疾患の理解】 臓器特異的自己免疫疾患 原発性胆汁性肝硬変2013

    • Author(s)
      石橋大海、下田慎治、中村 稔
    • Journal Title

      最新医学

      Volume: 68 Pages: 1326-1334

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population2013

    • Author(s)
      Migita K, Nakamura M, Abiru S, Jiuchi Y, Nagaoka S, Komori A, Hashimoto S, Bekki S, Yamasaki K, Komatsu T, Shimada M, Kouno H, Hijioka T, Kohjima M, Nakamuta M, Kato M, Yoshizawa K, Ohta H, Nakamura Y, Takezaki E, Nishimura H, Sato T, Ario K, Hirashima N, Oohara Y, Naganuma A, Muro T, Sakai H, Mita E, Sugi K, Yamashita H, Makita F, Yatsuhashi H, Ishibashi H, Yasunami M
    • Journal Title

      PLoS One

      Volume: 8(8) Pages: 71382-71382

    • NAID

      120006986124

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Systemic and local expression levels of TNF-like ligand 1A and its decoy receptor 3 are increased in primary biliary cirrhosis.2013

    • Author(s)
      Aiba Y, Harada K, Komori A, Ito M, Shimoda S, Nakamura H, Nagaoka S, Abiru S, Migita K, Ishibashi H, Nakanuma Y, Nishida N, Kawashima M, Tokunaga K, Yatsuhashi H, Nakamura M.
    • Journal Title

      Liver Int.

      Volume: 34 Issue: 5 Pages: 679-688

    • DOI

      10.1111/liv.12296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590393, KAKENHI-PROJECT-23591006, KAKENHI-PROJECT-25860576, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26461012
  • [Journal Article] 【自己免疫性消化器疾患の病態にせまる】 原発性胆汁性肝硬変の自己抗原は何か2013

    • Author(s)
      石橋大海、下田慎治、中村稔
    • Journal Title

      分子消化器病

      Volume: 10 Pages: 131-137

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] 特集:自己免疫性肝胆膵疾患の病態解明の進歩. 原発性胆汁性肝硬変患者におけるTL1AとDcR3の臨床学的意義2013

    • Author(s)
      相葉 佳洋, 小森 敦正, 長岡 進矢, 阿比留 正剛, 右田 清志, 伊東 正博, 石橋 大海, 八橋 弘, 中村 稔
    • Journal Title

      消化器と免疫

      Volume: 49 Pages: 15-17

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Involvement of Commensal Bacteria may Lead to Dysregulated Inflammatory and Autoimmune Responses in a Mouse Model for Chronic Nonsuppurative Destructive Cholangitis.2012

    • Author(s)
      Haruta I, Kikuchi K, Nakamura M, Hirota K, Kato H, et al
    • Journal Title

      J Clin Immunol.

      Volume: Oct; 32(5) Pages: 1026-37

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Genome-wide Association Study Identifies TNFSF15 and POU2AF1 as Susceptibility Loci for Primary Biliary Cirrhosis in the Japanese Population.2012

    • Author(s)
      Nakamura M, Nishida N, Kawashima M, Aiba Y, Tanaka A, et al
    • Journal Title

      Am J Hum Genet.

      Volume: Oct 5; 91(4): Pages: 721-728

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Serum amyloid A (SAA) induces pentraxin 3(PTX3) production in rheumatoid synoviocytes2012

    • Author(s)
      Satomura K, Torigoshi T, Koga T, Maeda Y, Izumi Y, Jiuchi Y, Miyashita T, Yamasaki S, Kawakami A, Aiba Y, Nakamura M, Komori A, Sato J, Ishibashi H, Motokawa S, Migita K
    • Journal Title

      Mod Rheumatol

      Volume: (Epub ahead of print)

    • NAID

      10031167663

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis2012

    • Author(s)
      Shimoda S, Tsuneyama K, Kikuchi K, Harada K, Nakanuma Y, Nakamura M, Ishibashi H, Hisamoto S, Niiro H, Leung PS, Ansari AA, Gershwin ME, Akashi K
    • Journal Title

      Clin Exp Immunol

      Volume: 168 Pages: 279-284

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] the Japanese NHO-Liver -network study group. Hepatocellular carcinoma and survival in patients with autoimmune hepatitis (Japanese National Hospital Organization-autoimmune hepatitis prospective study)2012

    • Author(s)
      Migita K, Watanabe Y, Jiuchi Y, Nakamura Y, Saito A, Yagura M, Ohta H, Shimada M, Mita E, Hijioka T, Yamashita H, Takezaki E, Muro T, Sakai H, Nakamuta M, Abiru S, Komori A, Ito M, Yatsuhashi H, Nakamura M, Ishibashi H
    • Journal Title

      Liver Int

      Volume: 32 Pages: 837-844

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] PBCの疾患感受性遺伝子による病態の解明2012

    • Author(s)
      中村稔
    • Journal Title

      日本臨床免疫学会会誌

      Volume: 35(6) Pages: 503-510

    • NAID

      10031147894

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Genome-wide Association Study Identifies TNFSF15 and POU2AF1 as Susceptibility Loci for Primary Biliary Cirrhosis in the Japanese Population2012

    • Author(s)
      Nakamura M, Nishida N, Kawashima M, Aiba Y, Tanaka A, Yasunami M, Nakamura H, Komori A, Nakamuta M, Zeniya M, Hashimoto E, Ohira H, Yamamoto K, Onji M, Kaneko S, Honda M, Yamagiwa S, Nakao K, Ichida T, Takikawa H, Seike M, Umemura T, Ueno Y, Sakisaka S, Kikuchi K, Ebinuma H, Yamashiki N, Tamura S, Sugawara Y, Mori A, Yagi S, Shirabe K, Taketomi A, Arai K, Monoe K, Ichikawa T, Taniai M, Miyake Y, Kumagi T, Abe M, Yoshizawa K, Joshita S, Shimoda S, Honda K, Takahashi H, Hirano K, Takeyama Y, Harada K, Migita K, Ito M, Yatsuhashi H, Fukushima N, Ota H, Komatsu T, Saoshiro T, Ishida J, Kouno H, Kouno H, Yagura M, Kobayashi M, Muro T, Masaki N, Hirata K, Watanabe Y, Nakamura Y, Shimada M, Hirashima N, Komeda T, Sugi K, Koga M, Ario K, Takesaki E, Maehara Y, Uemoto S, Kokudo N, Tsubouchi H, Mizokami M, Nakanuma Y, Tokunaga K, Ishibashi H
    • Journal Title

      Am J Hum Genet

      Volume: 91(4) Pages: 721-728

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Involvement of Commensal Bacteria may lead to Dysregulated Inflammatory and Autoimmune Responses in a Mouse Model for Chronic Nonsuppurative Destructive Cholangitis2012

    • Author(s)
      Haruta I, Kikuchi K, Nakamura M, Hirota K, Kato H, Miyakawa H, Shibata N, Miyake Y, Hashimoto E, Shiratori K, Yagi J
    • Journal Title

      J Clin Immunol

      Volume: 32(5) Pages: 1026-37

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Positive anti-gp210 antibodies is a risk factor for poor biochemical response to ursodeoxycholic acid treatment in Japanese patients with primary biliary cirrhosis.2011

    • Author(s)
      Nakamura M, Ito M, Yamamoto K, Zeniya M, Ohira H, Hashimoto E, Honda M, Kaneko S, Ueno Y, Kikuchi K, Onji M, Shimoda S, Takikawa H, Tanaka A, Komori A, Yatsuhashi H,et al
    • Journal Title

      J Hepatol 2011

      Volume: 54,Suppl No1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Association analysis of cytotoxic T-lymphocyte antigen 4 gene polynmorphism with primary biliary cirrhosis.2011

    • Author(s)
      Joshita S, Umemura T, Yoshizawa K, Katsuyama Y, Tanaka E, Nakamura M, Ishibashi H, Ota M, Shinshu PBC Study Group.
    • Journal Title

      J.Hepatol 54

      Pages: 537-541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Single-nucleotide polymorphism analysis of the organic cation transporter 1 gene for the detection of onset and clinical progression in Japanese patients with primary biliary cirrhosis.2011

    • Author(s)
      Ohishi Y, Kohjima M, Fukushima N, Yoshimoto T, Fukuizumi K, Yada M, Ishibashi H, Nakamura M, Enjoji M, Nakamuta M.
    • Journal Title

      Hepatology 2011: 54, Supple 1199A-1200A.

      Volume: 54, Supple

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Serum Baff and APRIL levels in patients with PBC.2011

    • Author(s)
      Migita K, Ilyassova B, Kovzel EF, Nersesov A, Maeda Y, Komori A, Ito M, Yano K, Yatsuhashi H, Ishibashi H, Nakamura M
    • Journal Title

      Clin Immunol 134

      Pages: 217-225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Evaluation of risk factors for the development of cirrhosis in autoimmune hepatitis : Japanese NHO-AIH prospective study.2011

    • Author(s)
      Migita K, Watanabe Y, Jiuchi Y, Nakamura Y, Saito A, Yagura M, Morimoto H, Shimada M, Mita E, Hijioka T, Yamashita H, Takezaki E, Muro T, Sakai H, Nakamuta M, Abiru S, Yano K, Komori A, Yatsuhashi H, Nakamura M, Ishibashi H
    • Journal Title

      J Gastroenterol 46 Suppl 1

      Pages: 56-62

    • NAID

      10029030300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Positive anti-gp210 antibodies is a significant risk factor for bile duct loss, hepatitis and poor biochemical response to ursodeoxycholic acid treatment that lead to more severe progression in Japanese patients with primary biliary cirrhosis.2011

    • Author(s)
      Nakamura M, Ito M, Kondo H, Yamamoto K, Ohira H, Zeniya M, Tanaka A, Hashimoto E, Honda M, Kaneko S, Ueno Y, Kikuchi K, Shimoda S, Komori A, Harada K, Sakisaka S, Takikawa H, Onji M, et al
    • Journal Title

      Hepatology 2011; 54, Supple 1208A-1209A.

      Volume: 54, Supple

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Analysis of HLA-DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis (PBC) : the HLA-DRB1 polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBC.2011

    • Author(s)
      Nakamura M, Yasunami M, Kondo H, Horie H, Aiba Y, Komori A, Migita K, Yatsuhashi H, Ito M, Shimoda S, Ishbiashi H, PBC Study Group in NHOSLJ.
    • Journal Title

      Hepatol Res 40

      Pages: 494-504

    • NAID

      10026392072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] PBCの予後予測:自己抗体を基盤に2011

    • Author(s)
      中村稔、相葉佳洋、小森敦正、下田慎治、石橋大海
    • Journal Title

      肝胆膵 62

      Pages: 707-714

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] A polymorphism in the integrin alfa V subunit gene affects the progression of primary biliary cirrhosis in Japanese patients.2011

    • Author(s)
      Inamine T, Nakamura M, Kawauchi A, Shirakawa Y, Hashiguchi H, Aiba Y, Taketomi A, Shirabe K, Nakamuta M, Hayashi S, Saoshiro T, Komori A, Yatsuhashi H, Kondo S, Omagari K, etal
    • Journal Title

      J Gastroenterol

      Volume: 46 Pages: 676-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Long term bacterial exposure can trigger nonsuppurative destructive cholangitis associated with multifocal epithelial inflammation.2011

    • Author(s)
      Haruta I, Kikuchi K, Hashimoto E, Nakamura M, Miyakawa H, et al.
    • Journal Title

      Lab Invest 90

      Pages: 577-588

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] A polymorphism in the integrin αV subunit gene affects the progression of primary biliary cirrhosis in Japanese patients2011

    • Author(s)
      Inamine T, Nakamura M, Kawauchi A, Shirakawa Y, Hashiguchi H, Aiba Y, et al
    • Journal Title

      J Gastroenterol

      Volume: 46 Pages: 676-686

    • NAID

      10029029298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] PBCの病態の多様性と治療ガイドライン2011

    • Author(s)
      石橋大海、下田慎治、小森敦正、中村稔
    • Journal Title

      肝胆膵 62

      Pages: 715-722

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Genetic polymorphisms of CTLA4 and SLC4A2 are differently associated with the pathogenesis of primary biliary cirrhosis in Japanese patients.2011

    • Author(s)
      Aiba Y, Nakamura M, Joshita S, Inamime T, Komori A, Yoshizawa K, Umemura T, Horie H, Migita K, Yatsuhashi H, Nakamuta M, Fukushima N, Saoshiro T, Hayashi S, Kouno et al
    • Journal Title

      J Gastroenterol 2011

      Volume: 46 Pages: 1203-1212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] The genetic polymorphisms of CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients2011

    • Author(s)
      Aiba Y, Nakamura M, Joshita S, Inamine T, Komori A, Yoshizawa K, et al
    • Journal Title

      J Gastroenterol

      Volume: May 19(In press)

    • NAID

      10030294477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] 自己免疫性胆管疾患の病態形成への自然免疫の関与2011

    • Author(s)
      小森敦正、中村稔、石橋大海
    • Journal Title

      肝胆膵 62

      Pages: 639-643

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Risk factors and prediction of long-term outcome in primary biliary cirrhosis.2011

    • Author(s)
      Ishibashi H, Komori A, 下田慎治, Ambrosini YM, Gershwin ME, Nakamura M
    • Journal Title

      Intern Med 50

      Pages: 1-10

    • NAID

      130000413190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] A polymorphism in the integrin・V subunit gene affects the progression of primary biliary cirrhosis in Japanese patients.2011

    • Author(s)
      Inamine T, Nakamura M, Kawauchi A, Shirakawa Y, Hashiguchi H, Aiba Y, Taketomi A, Shirabe K, Nakamuta M, Hayashi S, Saoshiro T, Komori A, Yatsuhashi H, Kondo S, Omagari K, Maehara Y, Ishibashi H, Tsukamoto K, the PBC Study Group in NHOSLJ.
    • Journal Title

      J Gastroenterol 46

      Pages: 676-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] PBCに関与するHLA個体差2011

    • Author(s)
      中村稔、石橋大海、安波道郎
    • Journal Title

      肝胆膵 62

      Pages: 945-952

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] The genetic polymorphisms of CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliarycirrhosis in Japanese patients.2011

    • Author(s)
      Aiba Y, Nakamura M, Joshita S, Inamime T, Komori A, Yoshizawa K, Umemura T, Migita K, Yatsuhashi H, Nakamuta M, Fukushima N, Saito A, Kouno H, Ota H, Muro T, Hayashi S, Watanabe Y, Nakamura Y, Komeda T, Shimada M, Tsukamoto K, Tanaka E, Ishibashi H, the PBC Study Group in NHOSLJ.
    • Journal Title

      J Gastroenterol Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Analysis of HLA-DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis(PBC): the HLA-DRB1 polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBC.2010

    • Author(s)
      Nakamura M, Yasunami M, Kondo H, Horie H, Aiba Y, et al.
    • Journal Title

      Hepatol Res 40

      Pages: 494-504

    • NAID

      10026392072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] 原発性胆汁性肝硬変ガイドラインの作成2010

    • Author(s)
      石橋大海、小森敦正、中村稔、下田慎治
    • Journal Title

      肝胆膵 Vol.60, No9

      Pages: 257-264

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Association analysis of cytotoxic T-lymphocyte antigen 4 gene polynmorphism with primary biliary cirrhosis2010

    • Author(s)
      Joshita S, Umemura T, Yoshizawa K, Katsuyama Y, Tanaka E, Nakamura M, et al
    • Journal Title

      J Hepatol

      Volume: 53 Pages: 537-541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients.2010

    • Author(s)
      Joshita S, Umemura T, Yoshizawa K, Katsuyama Y, Tanaka E, Nakamura M, et al
    • Journal Title

      J Hepatol (in press)

    • NAID

      120007110444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] 胆汁酸の排泄に関与するABCトランスポーター多型と原発性胆汁性肝硬変の重症化との関連2010

    • Author(s)
      塚元和弘、大曲勝久、中村稔
    • Journal Title

      臨床薬理の進歩

      Pages: 73-86

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Liver architecture, cell function, and disease.2009

    • Author(s)
      Ishibashi H, Nakamura M, Komori A, Migita K,Shimoda S
    • Journal Title

      Semin immunopathol 31

      Pages: 399-409

    • NAID

      120006984110

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article]2009

    • Author(s)
      中村稔、塚元和弘、安波道郎、近藤久義、中牟田誠, et al.
    • Journal Title

      Multidrug resistant protein 3(MDR3)遺伝子多型による原発性胆汁性肝硬変の予後遺伝子診断、消化器疾患におけるエピゲノミクス、第16回浜名湖シンポジウム論文集(アークメデイア)

      Pages: 81-83

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Increased expression of toll-like- receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers.2008

    • Author(s)
      Nakamura M, Funami K, Komori A, Yokoyama T, Aiba Y, Araki A, Takii Y, Ito M, Matsuyama M, Koyabu M, Migita K, Taniguchi K, Fujioka H, Yatsuhashi H, Matsumoto M, Ishibashi H, Seya T
    • Journal Title

      Hepatol Int 2

      Pages: 222-230

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis2008

    • Author(s)
      Ohishi Y, Nakamura M, Iio N, Higa S, Inayoshi M, et al
    • Journal Title

      Hepatology 48

      Pages: 853-862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] <クリニカル・トピックス>原発性胆汁性肝硬変における抗gp210抗体の臨床的意義2008

    • Author(s)
      中村稔, 下田愼治, 小森敦正, 石橋大海
    • Journal Title

      BIO Clinica 23(12)

      Pages: 1136-1143

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] CD4 T-cell autoreactivity to the mitochondrial autoantigen PDC-E2 in AMA-negative primary biliary cirrhosis.2008

    • Author(s)
      Shimoda S, Miyakawa H, Nakamura M, Ishibashi H, Kikuchi K, Kita H, Niiro H, Arinobu Y, Ono N, MacKay IR, Gershwin ME, Akashi K.
    • Journal Title

      J Autoimmun 31

      Pages: 110-115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Increased expression of toll-like-receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers2008

    • Author(s)
      Nakamura M, Funami K, Komori A, Yokoyama T, Aiba A, et al
    • Journal Title

      Hepatology International 2

      Pages: 222-230

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article]2008

    • Author(s)
      中村稔, 下田愼治, 小森敦正, 石橋大海
    • Journal Title

      BIO Clinica(原発性胆汁性肝硬変における抗gp210抗体の臨床的意義)

      Pages: 1136-1143

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] The predictive role of anti-gp210 and anti-centromere antibodies in the long-term outcome of PBC2007

    • Author(s)
      Nakamura M, Komori A, Ito M, Kondo H, Aiba Y, Migita K, et al.
    • Journal Title

      Hepatology Research (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis.2007

    • Author(s)
      Nakamura M, Kondo H, Ito M, et al.
    • Journal Title

      Hepatology 45

      Pages: 118-27

    • Data Source
      KAKENHI-PROJECT-17590330
  • [Journal Article] Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis.2007

    • Author(s)
      Nakamura M, Kondo H, Mori T, Komori A, Matsuyama M et al.
    • Journal Title

      Hepatology 45

      Pages: 118-127

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis.2007

    • Author(s)
      Nakamura M, Kondo H, Mori T, Komori A, Matsuyama M, Ito M et al.
    • Journal Title

      Hepatology 45

      Pages: 118-127

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] The predictive role of anti-gp210 and anti-centromere antibodies in the long-term outcome of PBC2007

    • Author(s)
      Nakamura M, Komori A, Ito M, Kondo H, Aiba Y, Migita K, Nagaoka S, et al.
    • Journal Title

      Hepatology Research (In press)

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis.2007

    • Author(s)
      Nakamura M, Takii Y, Ito M, et al.
    • Journal Title

      Hepatology 45

      Pages: 118-127

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590330
  • [Journal Article] Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis.2007

    • Author(s)
      Nakamura M, Kondo H, Mori T, Komori A, Matsuyama M, Ito M, Takii Y, Koyabu M, Yokoyama T, Migita K, Daikoku M, Abiru S, Yatsuhashi H, Takezaki E, Masaki N, Sugi K, Honda K, Adachi H, Nishi H, Watanabe Y, Nakamura Y, Shimada M, Komatsu T, Saito A, Soashiro T, Harada H, Sodeyama T, Hayashi S, Masumoto A, Sando T, Yamamoto T, SakaiH, Kobayashi M, Muro T, Koga M, Shums Z, Norman GL, Ishibashi H.
    • Journal Title

      Hepatology 45(1)

      Pages: 118-27

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590330
  • [Journal Article] コランジオサイトのセルサイクルとその制御 -コランジオサイト研究の最近の展開-2006

    • Author(s)
      小森敦正, 瀧井康, 石橋大海, 中村 稔
    • Journal Title

      肝胆膵 53

      Pages: 1065-1071

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Polymorhisms of interleukin-1beta in Japanese patients with hepatitis B virus infection.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Miyazoe S, Nakao K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      J Hepatol. (Epub ahead of print)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Feasibility study of ambulatory continuous infusion of 5-fluorouracil followed by cisplatin through hepatic artery for metastatic colorectal cancer.2006

    • Author(s)
      Qin B, Kato K, Mitsugi K, Nakamura M, Tanaka R, Baba E, Ariyama H, Kuroiwa T, Harada M, Nakano S.
    • Journal Title

      Cancer Chemother Pharmacol. 57(1)

      Pages: 114-119

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Human intra-hepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kB and MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K
    • Journal Title

      Liver International 26(4)

      Pages: 467-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] コランジオサイトのセルサイクルとその制御-コランジオサイト研究の最近の展開-2006

    • Author(s)
      小森敦正, 瀧井康, 石橋大海, 中村 稔
    • Journal Title

      肝胆膵 53

      Pages: 1065-1071

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, et al. Ishibashi H
    • Journal Title

      J Autoimmunity 26(2)

      Pages: 138-45

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira T, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Ishibashi H
    • Journal Title

      Liver Int. 26(4)

      Pages: 467-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T et al.
    • Journal Title

      J Autoimmunity 26

      Pages: 133-145

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Human intra-hepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kB and-MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M et al.
    • Journal Title

      Liver International (in press)

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] コランジオサイトの免疫環境-コランジオサイト研究の最近の展開-2006

    • Author(s)
      中村 稔, 小森敦正, 石橋大海
    • Journal Title

      肝胆膵 53

      Pages: 1085-1091

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Serum cytokine and soluble cytokine receptor levels in patients with non-alcoholic steatohepatitis.2006

    • Author(s)
      Abiru S, Migita K, Maeda Y, Daikoku M, Ito M, Ohata K, Nakamura M, Komori A, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Liver Int. 26(1)

      Pages: 39-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] コランジオサイトの免疫環境 -コランジオサイト研究の最近の展開-2006

    • Author(s)
      中村 稔, 小森敦正, 石橋大海
    • Journal Title

      肝胆膵 53

      Pages: 1085-1091

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Yokoyama T, Takii Y, Mori T, Yatsuhashi H, Eguchi K, Ishibashi H
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira T, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Ishibashi H
    • Journal Title

      Liver Int. 26(4)

      Pages: 467-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Relationship between serum resistin concentrations and inflammatory markers in patients with type 2 diabetes mellitus.2006

    • Author(s)
      Hui-Bing H, Migita K, Miyashita T, Maeda Y, Nakamura M, Yatsuhashi H, Ishibashi H, Eguchi K, Kimura H.
    • Journal Title

      Metabolism. 55

      Pages: 1670-1673

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Yokoyama T, Takii Y, Mori T, Yatsuhashi H, Eguchi K, Ishibashi H
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Incleased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, et al.
    • Journal Title

      J Autoimmun. 26

      Pages: 138-45

    • Data Source
      KAKENHI-PROJECT-17590330
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis2006

    • Author(s)
      Nakamura M, Takii Y, Ito M et al.
    • Journal Title

      J.Autoimmunity 26

      Pages: 138-145

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Serum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infection.2006

    • Author(s)
      Migita K, Abiru S, Maeda Y, Daikoku M, Ohata K, Nakamura M, Komori A, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Human Immunol. 67(1-2)

      Pages: 27-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] HLA-DRB1^*04 alleles in Japanese rheumatoid arthritis patients with AA amyloidosis.2006

    • Author(s)
      Migita K, Nakamura T, Maeda Y, Miyashita T, Origuchi T, Yatsuhashi Y, Nakamura M, Ishibashi H, Eguchi K.
    • Journal Title

      J Rheumatol. 33

      Pages: 2120-2123

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Immunosuppressive FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Yokoyama T, Takii Y, Mod T, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, et al., Ishibashi H.
    • Journal Title

      Liver International 26(4)

      Pages: 467-476

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Ishibashi H, et al.
    • Journal Title

      Life Science

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H.
    • Journal Title

      J.Autoimmunity 26(2)

      Pages: 138-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Ishibashi H, et al.
    • Journal Title

      Journal of Autoimmunity 26(2)

      Pages: 138-145

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Kondo H, Mori T, et al, Ishibashi H.
    • Journal Title

      Hepatology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H
    • Journal Title

      J.Autoimmunity 26(2)

      Pages: 138-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] IgA class antibodies to 2-oxo-acid dehydrogenase complex are not predictive markers of histopathological progression in primary biliary cirrhosis.2006

    • Author(s)
      Omagari K, Kadokawa Y, Nakamura M, Akazawa S, Ohba K, Ohnita K, Mizuta Y, Daikoku M, Yatsuhashi H, Ishibashi H, Kohno S.
    • Journal Title

      Autoimmunity 39(2)

      Pages: 107-112

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF- alpha- stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, et al., Ishibashi H.
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Guidelines for therapy of the chronic inflammatory liver diseases.2006

    • Author(s)
      Ishibashi H, Shimoda S, Nakamura M, Gershwin ME
    • Journal Title

      Seminars in Liver Disease (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Human intra-hepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kB and -MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira et al.
    • Journal Title

      Liver International (in press)

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] The serum levels of resistin in rheumatoid arthritis patients.2006

    • Author(s)
      Migita K, Maeda Y, Miyashita T, Kimura H, Nakamura M, Ishibashi H, Eguchi K.
    • Journal Title

      Clin Exp Rheumatol. 24

      Pages: 698-701

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H
    • Journal Title

      J.Autoimmunity 26(2)

      Pages: 138-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y etal.
    • Journal Title

      J Autoimmunity 26

      Pages: 133-145

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Shimoda S, Ishibashi H, et al.
    • Journal Title

      Journal of Hepatology 42(3)

      Pages: 386-392

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Biliary epithelial cells regulate autoreactive T cells : Implications for biliary-specific diseases.2005

    • Author(s)
      Kamihira T, Shimoda S, Nakamura M, et al.
    • Journal Title

      Hepatology 41

      Pages: 151-159

    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Biliary epithelial cells regulate autoreactive T cells : Implications for biliary-specific diseases2005

    • Author(s)
      Kamihira T, Shimoda S, Nakamura M et al.
    • Journal Title

      Hepatology 41

      Pages: 151-159

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Peroxynitrite-mediated matrix metalloproteinase-2 activation in human hepatic stellate cells.2005

    • Author(s)
      Migita K, Maeda Y, Abiru S, Komori A, Nakamura M, Ishibashi H, et al.
    • Journal Title

      FEBS Letter 579(14)

      Pages: 3119-3125

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, Komori A, Yokoyama T, Ueki T, Daikoku M, Yano K, Matsumoto T, Migita K, Yatsuhashi H, Ito M, Masaki N, Adachi H, Watanabe Y, Nakamura Y, Saoshiro T, Sodeyama T, Koga M, Shimoda S, Ishibashi H
    • Journal Title

      J.Hepatol. 42(3)

      Pages: 386-392

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Biliary epithelial cells regulate autoreactive T cells Implications for biliary-specific diseases.2005

    • Author(s)
      Kamihira T, Shimoda S, Nakamura M, Takii Y, et al.
    • Journal Title

      Hepatology 41

      Pages: 151-159

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Enhanced expression of type 1 interferon and toll-like receptor-3 in_primary biliary cirrhosis2005

    • Author(s)
      Takii Y, Nakamura M, Ito M et al.
    • Journal Title

      Laboratory Investigation (in press)

    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A, Shimizu-Yoshida Y, Nakao R, Kusumoto K, Nagaoka S, Yano K, Abiru S, Ueki T, Matsumoto T, Daikoku M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Nakashima M, Harada M, Ishibashi H.
    • Journal Title

      Lab Invest 85

      Pages: 908-920

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590330
  • [Journal Article] Biliary epithelial cells regulate autoreactive T cells : Implications for biliary-specific diseases.2005

    • Author(s)
      Kamihira T, Shimoda S, Nakamura M, Yokoyama T, Takii Y, Kawano A et al.
    • Journal Title

      Hepatology 41

      Pages: 151-159

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis2005

    • Author(s)
      Takii Y, Nakamura M, Ito M et al.
    • Journal Title

      Lab.Invest 85

      Pages: 908-920

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Enhanced expression of type 1 interferon and toll-like receptor-3 in primary biliary cirrhosis2005

    • Author(s)
      Takii Y, Nakamura M, Ito M et al.
    • Journal Title

      Laboratory Investigation (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M. Ito M. et al.
    • Journal Title

      Lab Invest 85

      Pages: 908-920

    • Data Source
      KAKENHI-PROJECT-17590330
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A et al., Ishibashi H
    • Journal Title

      Lab Invest. 85(7)

      Pages: 908-20

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis.2005

    • Author(s)
      Wang A-P, Migita K, Ito M, Takii Y, Daikoku M, Yokoyama T, Komori A, Nakamura M et al.
    • Journal Title

      J.Autoimmunity 25

      Pages: 85-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis.2005

    • Author(s)
      Wang AP, Migita K, Ito M, Takii Y, Nakamura M, Ishibashi H, et al.
    • Journal Title

      Journal of Autoimmunity 25(1)

      Pages: 85-91

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A, Ishibashi H, et al.
    • Journal Title

      Laboratory Investigation 85(7)

      Pages: 908-205

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Biliary epithelial cells regulate autoreactive T cells : implications for biliary-specific diseases.2005

    • Author(s)
      Kamihira T, Shimoda S, Nakamura M, Ishibashi H, et al.
    • Journal Title

      Hepatology 41(1)

      Pages: 151-159

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, Komori A, Yokoyama T et al.
    • Journal Title

      J.Hepatology 42

      Pages: 386-392

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis.2005

    • Author(s)
      Wang A-P, Migita K, Ito M, Takii Y, Daikoku M, Yokoyama T, Komori A, Nakamura M et al.
    • Journal Title

      J.Autoimmunity 25

      Pages: 85-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Biliary epithelial cells regulate autoreactive T cells : Implications for biliary-specific diseases.2005

    • Author(s)
      Kamihira T, Shimoda S, Nakamura M, Yokoyama T, Takii Y, Kawano A et al.
    • Journal Title

      Hepatology 41

      Pages: 151-159

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Biliary epithelial cells regulate autoreactive T cells : Implications for biliarv-specific diseases.2005

    • Author(s)
      Kamihira T, Shimoda S, Nakamura M, et al.
    • Journal Title

      Hepatology 41

      Pages: 151-159

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A, Shimizu-Yoshida Y, Nakao R, Kusumoto K, Nagaoka S, Yano K, Abiru S, Ueki T, Matsumoto T, Daikoku M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Nakashima M, Harada M, Ishibashi H
    • Journal Title

      Lab Invest. 85(7)

      Pages: 908-920

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A, Shimizu-Yoshida Y, Nakao R, Kusumoto K, Nagaoka S, Yano K, Abiru S, Ueki T, Matsumoto T, Daikoku M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Nakashima M, Harada M, Ishibashi H
    • Journal Title

      Lab Invest. 85(7)

      Pages: 908-920

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Biliary epithelial cells regulate autoreactive T cells : Implications for biliary-specific diseases.2005

    • Author(s)
      Kamihira T, Shimoda S, Nakamura M, Yokoyama T, Takii Y, Kawano A et al.
    • Journal Title

      Hepatology 41

      Pages: 151-159

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinicai parameter for monitoring primary biliary cirrhosis2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, et al.
    • Journal Title

      J.Hepatology 42

      Pages: 386-392

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, et al.
    • Journal Title

      J.Hepatology 42

      Pages: 386-392

    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, et al.
    • Journal Title

      Lab Invest 85

      Pages: 908-920

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590330
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005

    • Author(s)
      Nakamura M, Shimizu, Yoshida Y, Takii Y, et al. Ishibashi H
    • Journal Title

      J Hepatol. 42(3)

      Pages: 386-392

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y et al.
    • Journal Title

      J.Hepatology 42

      Pages: 386-392

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A et al.
    • Journal Title

      Laboratory Investigation (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, Komori A, Yokoyama T, Ueki T, Daikoku M, Yano K, Matsumoto T, Migita K, Yatsuhashi H, Ito M, Masaki N, Adachi H, Watanabe Y, Nakamura Y, Saoshiro T, Sodeyama T, Koga M, Shimoda S, Ishibashi H
    • Journal Title

      J.Hepatol. 42(3)

      Pages: 386-392

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Anti-gp210 antibody titers as a clinical parameter that predicts the long-term outcome of primary biliary cirrhosis under ursodeoxycholic acid treatment.2004

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, Komori A, Yokoyama T et al.
    • Journal Title

      AASLD Abstract #679 (October 31, 2004. Boston)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Innate immune responses in human intrahepatic biliary epithelial cells via Toll-like receptors.2004

    • Author(s)
      Komori A, Yokoyama T, Takii Y, Nakamura M, Shimoda S et al.
    • Journal Title

      AASLD Abstract #597 (October 31, 2004. Boston)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Lipopolysaccharide signaling induces serum amyloid A (SAA) synthesis in human hepatocytes in vitro.2004

    • Author(s)
      Migita K, Abiru S, Nakamura M, Komori A, Yoshida Y, Yokoyama T, Daikoku M, Ueki T, Takii Y, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      FEBS Let. 569(1-3)

      Pages: 235-239

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Lipopolysaccharide signaling induces serum amyloid A(SAA) synthesis in human hepatocytes in vitro.2004

    • Author(s)
      Migita K, Abiru S, Nakamura M, Komori A, Yoshida Y, Yokoyama T et al.
    • Journal Title

      FEBS Letters 569

      Pages: 235-239

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Lipopolysaccharide signaling induces serum amyloid A(SAA) synthesis in human hepatocytes in vitro.2004

    • Author(s)
      Migita K, Abiru S, Nakamura M, et al.
    • Journal Title

      FEBS Letters 569

      Pages: 235-239

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] T cell immunity and primary biliary cirrhosis.2003

    • Author(s)
      Ishibashi H., Nakamura M, Shimoda S, Gershwin ME.
    • Journal Title

      Autoimmunity Reviews 2(1)

      Pages: 19-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis.2003

    • Author(s)
      Shimoda S, Nakamura M, Ishibashi H, et al.
    • Journal Title

      Gastroenterology 124

      Pages: 1915-1925

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] 原発性胆汁性肝硬変の成因-ミトコンドリア抗原と免疫応答2003

    • Author(s)
      中村 稔, 下田慎治, 石橋大海
    • Journal Title

      臨床消化器内科 18

      Pages: 545-551

    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Promiscuous T cells selected by Escherichia coli OGDC-E2 in primary biliary cirrhosis2003

    • Author(s)
      Tanimoto H, Shimoda S, Nakamura M, et al.
    • Journal Title

      Autoimmunity 20

      Pages: 255-263

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Distinct costimulation dependent and independent autoreactive T-cell clones in primary biliary cirrhosis.2003

    • Author(s)
      Kamihira T, Shimoda S, Harada K, Kawano A, Handa M, Baba E, Tsuneyama K, Nakamura M, Ishibashi H, Nakanuma Y, Gershwin ME, Harada M.
    • Journal Title

      Gastroenterology 125(5)

      Pages: 1379-1387

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis.2003

    • Author(s)
      Shimoda S, Nakamura M, Ishibashi H, et al.
    • Journal Title

      Gastroenterology 124

      Pages: 1915-1925

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Promiscuous T cells selected by Escherichia coli OGDC-E2 in primary biliary cirrhosis.2003

    • Author(s)
      Tanimoto H, Shimoda S, Nakamura M, et al.
    • Journal Title

      Autoimmunity 20

      Pages: 255-263

    • Data Source
      KAKENHI-PROJECT-15591075
  • [Journal Article] Characterization of distinct costimulation dependent and independent autoreactive T cell clones in primary biliary cirrhosis.2003

    • Author(s)
      Kamihira T, Shimoda S, Harada K, Kawano A, Handa M, Baba E, Tsuneyama K, Nakamura M, Ishibashi H, et al.
    • Journal Title

      Gastroenterology 125

      Pages: 1379-1387

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Biliary epithelial cells and primary biliary cirrhosis : the role of liver- infiltrating mononuclear cells.

    • Author(s)
      Shimoda S, Harada K, Niiro H, Yoshizumi T, Soejima Y, Taketomi A, Maehara Y, Tsuneyama K, Nakamura M, Komori A, Migita K, Nakanuma Y, Ishibashi H, Selmi C, Gershwin ME.
    • Journal Title

      Hepatology 2008 47

      Pages: 958-65

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Single- nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis.

    • Author(s)
      Ohishi Y, Nakamura M, Iio N, Higa S, Inayoshi M, Aiba Y, Komori A, Omagari K, Ishibashi H, Tsukamoto K
    • Journal Title

      Hepatology 2008 48

      Pages: 853-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population.2023

    • Author(s)
      Knor SS, 植野和子, 西田奈央, 川嶋実苗, 河合洋介, 相葉佳洋, 人見祐基, 長﨑正朗, 中村稔, 徳永勝士
    • Organizer
      第6回関東HLA研究会
    • Data Source
      KAKENHI-PROJECT-23K07471
  • [Presentation] 原発性胆汁性胆管炎の新たな病態解明と治療標的の同定を目指した臨床ゲノム解析2023

    • Author(s)
      中村 稔, 植野和子, 相葉佳洋.
    • Organizer
      第59回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-23K07471
  • [Presentation] シンポジウム2; 消化器診療へのゲノムワイド研究のインパクト, 国際メタ GWAS によって同定された東アジア人特異的な原発性胆汁性胆管炎(PBC)感受性遺伝子領域に起因する発症機序の解明.2023

    • Author(s)
      人見祐基、中村 稔
    • Organizer
      第109回日本消化器病学会総会. 長崎 2023.4.7
    • Data Source
      KAKENHI-PROJECT-23K07366
  • [Presentation] 原発性胆汁性胆管炎のゲノムワイド関連解析による病態の解明2023

    • Author(s)
      相葉佳洋, 植野和子, 人見祐基, 小森敦正, 中村 稔.
    • Organizer
      第121回日本消化器病学会九州支部例会.
    • Data Source
      KAKENHI-PROJECT-23K07471
  • [Presentation] ワークショップ2; 肝胆膵免疫疾患の最新の知見,  原発性胆汁性胆管炎のトランスクリプトームデータを用いた治療標的遺伝子の探索2023

    • Author(s)
      相葉佳洋、植野和子, 中村 稔
    • Organizer
      第60回日本消化器免疫学会総会. 東京 2023.10.6
    • Data Source
      KAKENHI-PROJECT-23K07366
  • [Presentation] 国際メタ GWAS によって同定された原発性胆汁性胆管炎(PBC)感受性遺伝子領域 CD28 に由来する発症機序の解明.2023

    • Author(s)
      人見祐基, 相葉佳洋 中村 稔相葉佳洋, 西田奈央, 中村 稔.
    • Organizer
      第59回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-23K07471
  • [Presentation] パネルディスカッション2; 自己免疫性肝胆疾患診療の未来予想図(現状と課題),  原発性胆汁性胆管炎の新たな病態解明と治療標的の同定を目指した臨床ゲノム解析.2023

    • Author(s)
      中村 稔、植野和子、相葉佳洋
    • Organizer
      第59回日本肝臓学会総会.  奈良 2023.6.16
    • Data Source
      KAKENHI-PROJECT-23K07366
  • [Presentation] 自己免疫疾患感受性遺伝子に起因する発症機序の解明におけるCRISPR/Cas9の活用2023

    • Author(s)
      人見祐基, 植野和子, 相葉佳洋, 西田奈央, 川嶋実苗, Khor SS, 長崎正朗, 徳永勝士, 中村稔
    • Organizer
      日本ゲノム編集学会
    • Data Source
      KAKENHI-PROJECT-23K07471
  • [Presentation] 抗原提示補助シグナル分子の遺伝的バリアントに起因する自己免疫疾患感受性の分子機序の解明2023

    • Author(s)
      人見祐基, 植野和子, 相葉佳洋, 西田奈央, 河合洋介, 川嶋実苗, Knor SS, 長﨑正朗, 徳永勝士, 中村稔
    • Organizer
      第31回日本組織適合性学会
    • Data Source
      KAKENHI-PROJECT-23K07471
  • [Presentation] Identification of a gene expression regulatory variant in autoimmune diseasessusceptibility locus CD582023

    • Author(s)
      Yuki Hitomi, Kazuko Ueno, Yoshihiro Aiba, Nao Nishida, Yosuke Kawai, Minae Kawashima , Seik-Soon Khor, Sanami Takada, Chisato Iwabuchi, Masao Nagasaki, Katsushi Tokunaga, Minoru Nakamura
    • Organizer
      Human Genetics Asia 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07471
  • [Presentation] 原発性胆汁性胆管炎のトランスクリプトームデータを用いた治療標的遺伝子の探索2023

    • Author(s)
      相葉佳洋, 植野和子, 人見祐基, 伊東正博, 小森敦正, 中村 稔.
    • Organizer
      第60回日本消化器免疫学会総会.
    • Data Source
      KAKENHI-PROJECT-23K07471
  • [Presentation] PBC-GWAS の国際メタ解析とトランスクリプトームの統合解析による新規治療標的の同定2022

    • Author(s)
      植野和子, 中村 稔, 相葉佳洋
    • Organizer
      第58回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 原発性胆汁性胆管炎の疾患感受性遺伝子 POU2AF1 が制御する遺伝子の検討2022

    • Author(s)
      相葉佳洋, 植野和子, 人見祐基, 西田奈央, 小森敦正, 阿比留正剛, 長岡進矢, 八橋 弘, 中村 稔
    • Organizer
      第58回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] Transcriptome and GWAS identified IL4, IL5, and GATA2 as critical upstream regulators in blood and IFNG in liver for eosinophilia in primary biliary cholangitis2022

    • Author(s)
      植野和子, 人見祐基, 相葉佳洋, Gervais Olivier, 河合洋介, Khor Seik Soon, 川嶋実苗, 西田奈央, 小島要, 長崎正朗, 徳永勝士, 中村稔
    • Organizer
      2022 American Society of Human Genetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 国際メタ GWAS によって同定された原発性胆汁性胆管炎(PBC)感受性遺伝子領域 CCR6/FGFR1OP に由来する発症機序の解明2022

    • Author(s)
      人見祐基, 相葉佳洋, 中村 稔
    • Organizer
      第58回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 様々な免疫形質と関連するCD28領域におけるスプライシング制御バリアントの同定 Identification of splicing regulatory variants in multiple immunological traits-susceptibility locus CD28"2022

    • Author(s)
      人見祐基, 相葉 佳洋, 植野 和子, 西田 奈央, 河合 洋介, 川嶋 実苗, 築地 信, 岩渕 千里, 高田 紗奈美, 三宅 紀子, 長崎 正朗, 徳永 勝士, 中村 稔
    • Organizer
      日本人類遺伝学会第67回大会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 原発性胆汁性胆管炎の肝組織におけるPOU2AF1とその関連遺伝子の解析2022

    • Author(s)
      相葉佳洋, 伊東正博, 植野和子, 人見祐基, 小森敦正, 阿比留正剛, 長岡進矢, 八橋 弘, 長崎正朗, 徳永勝士, 中村 稔
    • Organizer
      第50回日本臨床免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] Transcriptome and GWAS identified rs2238678 as a critical SNP for eosinophilia in primary biliary cholangitis2021

    • Author(s)
      Kazuko Ueno,Yosuke Kawai,Yuki Hitomi,Yoshihiro Aiba,Mayumi Ueta,Minoru Nakamura,Katsushi Tokunaga,Masao Nagasaki
    • Organizer
      ASHG2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 原発性胆汁性胆管炎における疾患感受性遺伝子 POU2AF1 とその関連遺伝子の解析.2021

    • Author(s)
      相葉佳洋、植野和子、 人見祐基、 西田奈央、 下田慎治、 小森敦正、 橋元 悟、戸次鎮宗、 阿比留正剛、 長岡進、八橋 弘、 中村 稔.
    • Organizer
      第57回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 肝組織アレイデータに基づいた日本人原発性胆汁性胆管炎の疾患感受性遺伝子 POU2AF1 とその関連遺伝子の解析.2021

    • Author(s)
      相葉佳洋、植野和子、人見祐基、小森敦正、橋元悟、戸次鎮宗、阿比留正剛、長岡進矢、八橋弘、中村稔
    • Organizer
      第58回日本消化器免疫学会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene CCR6/FGFR1OP2021

    • Author(s)
      Yuki Hitomi, Yoshihiro Aiba, Makoto Tsuiji,Minoru Nakamura
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 原発性胆汁性胆管炎(PBC)感受性遺伝子CCR6/FGFR1OPにおけるprimary functional variantsの同定2021

    • Author(s)
      人見祐基、相葉佳洋、西田奈央、河合洋介、川嶋実苗、安波道朗、Olivier Gervais、長﨑正朗、徳永勝士、築地信、中村稔
    • Organizer
      第66回人類遺伝学会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] Applying the regional heritability mapping method to primary biliary cholangitis in the Japanese population2021

    • Author(s)
      Olivier Gervais, Yoshihiro Aiba, Kazuko Ueno, Yosuke Kawai, Nao Nishida, Minae Kawashima, Olivier Gervais, Masao Nagasaki, Katsushi Tokunaga, Makoto Tsuiji, Minoru Nakamura
    • Organizer
      ASHG2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] Identification of seven primary functional variants in primary biliary cholangitis susceptibility loci in the Japanese population2021

    • Author(s)
      Yuki Hitomi, Yoshihiro Aiba, Yosuke Kawai, Kaname Kojima, Kazuko Ueno, Nao Nishida, Minae Kawashima, Olivier Gervais, Seik-Soon Khor, Masao Nagasaki, Katsushi Tokunaga, Minoru Nakamura, Makoto Tsuiji
    • Organizer
      ASHI2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] rs1944919 on human chromosome 11q23.1 and its effector genes COLCA1 and COLCA2 confer susceptibility to primary biliary cholangitis2021

    • Author(s)
      Yuki Hitomi, Yoshihiro Aiba, Yosuke Kawai, Kaname Kojima, Kazuko Ueno, Nao Nishida, Minae Kawashima, Olivier Gervais, Seik-Soon Khor, Masao Nagasaki, Katsushi Tokunaga, Minoru Nakamura, Makoto Tsuiji
    • Organizer
      2021 American Society for Histocompatibility and Immunogenetics Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] COLCA1 and COLCA2, the effector genes driven by rs1944919 in primary biliary cholangitis (PBC) susceptibility locus chromosome 11q23.1 in the Japanese population2021

    • Author(s)
      Yuki Hitomi, Yoshihiro Aiba, Yosuke Kawai, Kaname Kojima, Kazuko Ueno, Nao Nishida, Minae Kawashima, Olivier Gervais, Seik-Soon Khor, Masao Nagasaki, Katsushi Tokunaga, Makoto Tsuiji, Minoru Nakamura
    • Organizer
      APASL STC 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] Integrated GWAS and mRNA microarray analysis identified IFNG and CD40L as the central upstream regulators in primary biliary cholangitis2020

    • Author(s)
      Kazuko Ueno, Yoshihiro Aiba, Yuki Hitomi, Shinji Shimoda, Hitomi Nakamura, Olivier Gervai, Yosuke Kawai, Seik-Soon Khor, Minae Nao Nishida, Kaname Kojima, Kawashima, Nao Nishida,Atsumasa Komori, Hiroshi Yatsuhashi, Atsushi Tanaka, Masao Nagasaki, Katsushi Tokunaga, Minoru Nakamura, and PBC-GWAS consortium in Japan
    • Organizer
      ヨーロッパ肝臓学会総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 発性胆汁性胆管炎に関与する遺伝子の共発現ネットワーク解析.2020

    • Author(s)
      相葉佳洋、植野和子、人見祐基、小森敦正、橋元悟、戸次鎮宗、阿比留正剛、長岡進矢、黒木保、八橋弘、中村稔
    • Organizer
      第56回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] 原発性胆汁性胆管炎に関与する遺伝子の共発現ネットワーク解析2020

    • Author(s)
      相葉佳洋, 植野和子, 人見祐基, 小森敦正, 橋元 悟, 戸次鎮宗, 阿比留正剛, 長岡進矢, 八橋 弘, 中村 稔.
    • Organizer
      第56回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 原発性胆汁性胆管炎(PBC)感受性遺伝子領域Chromosome 11q23.1におけるeffector遺伝子COLCA1およびCOLCA2の同定 COLCA1/COLCA2, the effector genes in primary biliary cholangitis susceptibility locus chromosome 11q23.12020

    • Author(s)
      人見祐基, 相葉佳洋, 河合洋介, 児島要, 植野和子, 西田奈央, 川嶋実苗, Olivier Gervais, Seik-Soon Khor,長﨑正朗, 徳永勝士, 中村稔, 築地信
    • Organizer
      第65回日本人類遺伝学会
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] The analysis of POU2AF1 and its related molecules in the pathogenesis of primary biliary cholangitis by using GWAS and transcriptome datasets2020

    • Author(s)
      Yoshihiro Aiba, Kazuko Ueno, Yuki Hitomi, Olivier Gervais, Yosuke Kawai, Minae Kawashima, Nao Nishida, Kaname Kojima, Masao Nagasaki, Katsushi Tokunaga, Minoru Nakamura
    • Organizer
      第70回アメリカ人類遺伝学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08370
  • [Presentation] 原発性胆汁性胆管炎の肝組織網羅的遺伝子発現データを用いた疾患感受性遺伝子ならびに疾患関連pathwayの解析.2019

    • Author(s)
      相葉佳洋、西田奈央, 人見祐基, 小森敦正, 八橋 弘, 中村 稔.
    • Organizer
      第55回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] 原発性胆汁性胆管炎の肝組織網羅的遺伝子発現データを用いた疾患感受性遺伝子ならびに疾患関連pathwayの解析2019

    • Author(s)
      相葉佳洋、西田奈央, 人見祐基, 小森敦正, 八橋 弘, 中村 稔.
    • Organizer
      第55回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] 技術革新がもたらした消化器研究のパラダイムシフト PBC診断・治療バイオマーカーと新たな治療標的分子の確立2019

    • Author(s)
      下田 慎治, 原田 憲一, 中村 稔
    • Organizer
      第105回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-17H04164
  • [Presentation] Role of PRKCB in the development of primary biliary cholangitis2019

    • Author(s)
      Aiba Y, Hitomi Y, Ueno K, Nakamura M.
    • Organizer
      The 48th Annual Meeting of the Japanese Society of Immunology
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] Integrated analysis of GWAS and mRNA expression array identified IFNG and CD40L as the most significant upstream-regulators in primary biliary cholangitis.2019

    • Author(s)
      Ueno K, Aiba Y, Hitomi Y, Shimoda S, O Gervais, Kawai Y, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, Nakamura M.
    • Organizer
      The 69th Annual Meeting of The American Society of Human Genetics (ASHG 2019).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] PBC診断・治療バイオマーカーと新たな治療標的分子の確立.2019

    • Author(s)
      下田慎治, 原田憲一、中村 稔
    • Organizer
      第105回日本消化器病学会総会.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Integrated analysis of GWAS and mRNA expression array identified IFNG and CD40L as the most significant upstream-regulators in primary biliary cholangitis.2019

    • Author(s)
      Ueno K, Aiba Y, Hitomi Y, Shimoda S, O Gervais, Kawai Y, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, Nakamura M.
    • Organizer
      The 69th Annual Meeting of The American Society of Human Genetics.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] Integrated analysis of GWAS and mRNA microarray identified IFNG and CD40L as the central upstream-regulators in primary biliary cholangitis2019

    • Author(s)
      Ueno K, Aiba Y, Hitomi Y, Shimoda S, O Gervais, Kawai Y, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, Nakamura M and PBC-GWAS Consortium in Japan.
    • Organizer
      The International Liver Congress 2019 (ILC2019).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] Pathway-Analysis Using Datasets of GWAS and mRNA Expression Array Identified IFNG as the Most Significant Upstream-Regulator in Primary Biliary Cholangitis.2019

    • Author(s)
      Ueno K, Aiba Y, Hitomi Y, Shimoda S, Tanaka A, Olivier Gervais, Kawai Y, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, Nakamura M, PBC-GWAS consortium in Japan.
    • Organizer
      APASL STC Tokyo 2019.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] 自己免疫性肝疾患:病態解明と治療法の進歩 新たなPBC治療標的分子の同定と治療へのアプローチ,2019

    • Author(s)
      下田 慎治, 原田 憲一, 中村 稔
    • Organizer
      第55回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-17H04164
  • [Presentation] Genetics of Autoimmune Liver Disease.2019

    • Author(s)
      Nakamura M.
    • Organizer
      APASL STC Tokyo 2019.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] 原発性胆汁性胆管炎(PBC)感受性遺伝子領域に起因する発症機序の解明におけるゲノム編集技術の応用.2019

    • Author(s)
      人見祐基, 河合洋介, 植野和子, 西田奈央, 川嶋実苗, 相葉佳洋, Olivier Gervais, Seik-Soon Khor, 築地 信, 長崎正朗, 中村 稔, 徳永勝士.
    • Organizer
      日本人類遺伝学会第64回大会.
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] 新たなPBC治療標的分子の同定と治療へのアプローチ.2019

    • Author(s)
      下田慎治, 原田憲一、中村 稔
    • Organizer
      第55回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] POGLUT1, The Effector Gene Driven by rs2293370 in Primary Biliary Cholangitis (PBC) Susceptibility Locus Chromosome 3q13.33 in The Japanese Population.2019

    • Author(s)
      Hitomi Y, Ueno K, Kawai Y, Nishida N, Kojima K, Kawashima M, Aiba Y, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, Nakamura M, PBC-GWAS Consortium in Japan.
    • Organizer
      APASL STC Tokyo 2019.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] The role of PRKCB in the development of primary biliary cholangitis2019

    • Author(s)
      Aiba Y, Ueno K, Hitomi Y, Kawashima M, Nishida N, Kawai Y, Komori A, Yatsuhashi H, Nagasaki M, Tokunaga K, Nakamura M and PBC-GWAS consortium in Japan
    • Organizer
      AASLD THE LIVER MEETING 2019.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] 日本人原発性胆汁性胆管炎(PBC)感受性遺伝子領域3番染色体長腕13.33に位置するcausal variantおよびエフェクター遺伝子POGLUT1の同定.2019

    • Author(s)
      人見祐基, 中村 稔
    • Organizer
      第55回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Identification of novel biliary epithelial cell biomarkers in primary biliary cholangitis (PBC).2019

    • Author(s)
      Shimoda S, Harada K, Nakamura M , et al.
    • Organizer
      AASLD THE LIVER MEETING 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Integrated analysis of GWAS and mRNA microarray revealed IFN-g as the most significant signature in the disease-pathways of primary biliary cholangitis in the Japanese population2018

    • Author(s)
      Yoshihiro Aiba, Kazuko Ueno, Shinji Shimoda, Yuki Hitomi, Minae Kawashima, Nao Nishida, Yosuke Kawai, Atsumasa Komori, Hiroshi Yatsuhashi, Masao Nagasaki, Katsushi Tokunaga, Minoru Nakamura, PBC-GWAS consortium in Japan et al.
    • Organizer
      AASLD 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population.2017

    • Author(s)
      M. Kawashima, N. Nishida, Y. Hitomi, K. Kojima, Y. Kawai, Y. Aiba, H. Nakamura, M. Nagasaki, K. Tokunaga, M. Nakamura
    • Organizer
      American Society of Human Genetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene loci NFKB1/MANBA.2017

    • Author(s)
      Y. Hitomi, K. Nakatani, K. Kojima, N. Nishida, Y. Kawai, M. Kawashima, Y. Aiba, M. Nagasaki, M. Nakamura, K. Tokunaga
    • Organizer
      American Society of Human Genetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] Principal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese population.2017

    • Author(s)
      Yasunami M, Nakamura H, Tokunaga K, Kawashima M, Nishida N, Hitomi Y, Nakamura M.
    • Organizer
      The 46th Annual Meeting of The Japanese Society for Immunology.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] 日本人原発性胆汁性胆管炎における黄疸型進行関連遺伝子の同定と発現・機能解析2017

    • Author(s)
      相葉佳洋, 西田奈央, 人見祐基, 川嶋実苗, 徳永勝士, 中村 稔
    • Organizer
      第45回日本臨床免疫学会総会.
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] Identification of the disease causal variants in human primary biliary cholangitis (PBC) susceptibility gene loci NFKB1/MANBA.2017

    • Author(s)
      Hitomi Y, Aiba Y, Nakamura M, Tokunaga K.
    • Organizer
      The 46th Annual Meeting of The Japanese Society for Immunology.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Genome-wide Association Studies Identify PRKCB as A Novel Genetic Susceptibility Locus for Primary Biliary Cholangitis in the Japanese Population.2017

    • Author(s)
      Nakamura M, Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Komori A, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, PBC consortium in Japan.
    • Organizer
      The 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL 2017)
    • Place of Presentation
      Shanghai(China)
    • Year and Date
      2017-02-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 日本人原発性胆汁性胆管炎における黄疸型進行関連遺伝子の同定と発現・機能解析.2017

    • Author(s)
      相葉佳洋, 西田奈央, 人見祐基, 川嶋実苗, 徳永勝士, 中村 稔
    • Organizer
      第45回日本臨床免疫学会総会.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] GWAS polygenic model approach applied to primary biliary cholangitis (PBC) in a Japanese population.2017

    • Author(s)
      O. Gervais, Ueno K, Kojima K, Aiba Y, Kawashima M, Kawai Y, Hitomi Y, Tokunaga K, Nakamura M, Nagasaki M.
    • Organizer
      ASHG 2017(The 67th Annual Meeting of the American Society of Human Genetics)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Increased expression and altered localization of cathepsin Z is associated with progression to end-stage hepatic failure in primary biliary cholangitis2017

    • Author(s)
      Yoshihiro Aiba, Kenichi Harada, Masahiro Ito, Shinichi Aishima, Atsumasa Komori, Hiroshi Yatsuhashi, Minoru Nakamura and Headquarters of PBC Research in the National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
    • Organizer
      EASL 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] 原発性胆汁性胆管炎の重症化にカテプシンの果たす役割の検討2017

    • Author(s)
      相葉佳洋, 原田憲一, 相島慎一, 伊東正博, 人見祐基, 西田奈央, 小森敦正, 八橋 弘, 中村 稔
    • Organizer
      第53回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene loci NFKB1/MANBA.2017

    • Author(s)
      Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
    • Organizer
      ASHG 2017(The 67th Annual Meeting of the American Society of Human Genetics).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Increased expression and altered localization of cathepsin Z is associated with progression to jaundice-stage in primary biliary cholangitis2017

    • Author(s)
      Aiba Y, Harada K, Ito M, Aishima S, Hitomi Y, Nishida N, Kawashima M, Uemoto S, Kokudo N, Takatsuki M, Eguchi S, Shimoda S, Nakamura H, Komori A, Abiru S, Nagaoka S, Yatsuhashi H, Tokunaga K, Nakamura M
    • Organizer
      AASLD The Liver Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09449
  • [Presentation] 病態解明のための遺伝学的アプローチ2017

    • Author(s)
      中村 稔
    • Organizer
      School of AutoImmune Liver Disease(SAIL)
    • Place of Presentation
      セミナーハウス クロス・ウェーブ幕張(千葉県千葉市)
    • Year and Date
      2017-01-07
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 難治性肝胆道疾患(PBC/PSC/AIH)診療の進歩と今後の課題 原発性胆汁性胆管炎(PBC)の新規治療開発に向けて2017

    • Author(s)
      下田 慎治, 小野原 伸也, 中村 稔, 原田 憲一
    • Organizer
      第53回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-17H04164
  • [Presentation] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population.2017

    • Author(s)
      Kawashima M, Nishida N, Hitomi Y, Kojima K, Kawai Y, Aiba Y, Nakamura H, Nagasaki M, Tokunaga K, Nakamura M.
    • Organizer
      ASHG 2017(The 67th Annual Meeting of the American Society of Human Genetics)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] 原発性胆汁性胆管炎(PBC)模倣培養系とゲノムワイド関連解析(GWAS)を統合して得られる遺伝子情報の機能解析.2017

    • Author(s)
      下田慎治, 小野原伸也, 中村 稔.
    • Organizer
      第53回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] 原発性胆汁性胆管炎(PBC)感受性遺伝子NFKB1/MANBAを対象とした、第一義的な機能的遺伝子 多型の同定研究2017

    • Author(s)
      人見 祐基、仲谷 健、小島 要、 西田 奈央、河合 洋介、川嶋 実苗、 相葉 佳洋、長崎 正朗、中村 稔、 徳永 勝士
    • Organizer
      日本人類遺伝学会
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] 原発性胆汁性胆管炎の重症化にカテプシンの果たす役割の検討.2017

    • Author(s)
      相葉佳洋, 原田憲一, 相島慎一, 伊東正博, 人見祐基, 西田奈央, 小森敦正, 八橋 弘, 中村 稔.
    • Organizer
      第53回日本肝臓学会総会.
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Imputation analysis using reference panel of 1,070 Japanese individuals (1KJPN) and in silico / in vitro functional analyses identified functional variants for primary biliary cirrhosis (PBC) susceptibility.2017

    • Author(s)
      Hitomi Y, Kojima K, Kawashima M, Kawai Y, Nishida N, Aiba Y, Yasunami M, Nagasaki M, Nakamura M, Tokunaga K
    • Organizer
      The 13th International Congress of Human Genetics
    • Place of Presentation
      京都国際会議場(京都府京都市)
    • Year and Date
      2017-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] 自己免疫性肝疾患のパラダイムシフト 原発性胆汁性胆管炎(PBC)模倣培養系とゲノムワイド関連解析(GWAS)を統合して得られる遺伝子情報の機能解析2017

    • Author(s)
      下田 慎治, 小野原 伸也, 中村 稔
    • Organizer
      第103回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-17H04164
  • [Presentation] 原発性胆汁性胆管炎(PBC)の新規治療開発に向けて2017

    • Author(s)
      下田慎治, 小野原伸也, 中村 稔, 原田憲一.
    • Organizer
      第53回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Increased expression and altered localization of cathepsin Z is associated with progression to jaundice-stage in primary biliary cholangitis.2017

    • Author(s)
      Aiba Y, Harada K, Ito M, Aishima S, Hitomi Y, Nishida N, Kawashima M, Uemoto S, Kokudo N, Takatsuki M, Eguchi S, Shimoda S, Nakamura H, Komori A, Abiru S, Nagaoka S, Yatsuhashi H, Tokunaga K, Nakamura M.
    • Organizer
      AASLD The Liver Meeting 2017.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Genome-wide haplotype-based association study reveals novel non-HLA susceptibility loci for primary biliary cirrhosis in Japanese cohorts.2017

    • Author(s)
      C. Im, Y. Sapkota, Nakamura M, Tokunaga K, Yasui Y.
    • Organizer
      ASHG 2017(The 67th Annual Meeting of the American Society of Human Genetics)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Genome-wide Association Studies Identify PRKCB as A Novel Genetic Susceptibility Locus for Primary Biliary Cholangitis in the Japanese Population.2017

    • Author(s)
      Nakamura M, Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Komori A, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, PBC consortium in Japan.
    • Organizer
      The 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL 2017).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] GWAS polygenic model approach applied to primary biliary cholangitis (PBC) in a Japanese population.2017

    • Author(s)
      O. Gervais, K. Ueno, K. Kojima, Y. Aiba, M. Kawashima, Y. Kawai, Y. Hitomi, K. Tokunaga, M. Nakamura, M. Nagasaki
    • Organizer
      American Society of Human Genetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] 原発性胆汁性胆管炎(PBC)模倣培養系とゲノムワイド関連解析(GWAS)を統合して得られる遺伝子情報の機能解析2017

    • Author(s)
      下田慎治, 小野原伸也, 中村 稔
    • Organizer
      第103回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-17H04169
  • [Presentation] Controlled-access databases for genetic and phenotypic human data in Japan.2017

    • Author(s)
      Y. Kodama, A. Fukuda, J. Mashima, M. Minowa, M. Kawashima, K. Miyazaki, N. Mitsuhashi, E. Kaminuma, O. Ogasawara, K. Okubo, Y. Nakamura, T. Takagi
    • Organizer
      American Society of Human Genetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] Genome-wide association study identifies PRKCB as a novel genetic factor for primary biliary cirrhosis in the Japanese population2016

    • Author(s)
      M. Kawashima , Y. Hitomi , N. Nishida , K. Kojima , Y. Kawai , H. Nakamura , K. Chayama , Y. Aiba , M. Nagasaki , K. Tokunaga , M. Nakamura , PBC Consortium in Japan (PBCCSJ)
    • Organizer
      American Society of Human Genetics 2017 Annual Meeting
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2016-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] 日本人原発性胆汁性肝硬変における黄疸・肝不全進行関連遺伝子の同定2016

    • Author(s)
      相葉佳洋,西田奈央,中村 稔
    • Organizer
      第52回 日本肝臓学会総会
    • Place of Presentation
      ホテルニューオオタニ幕張 東京ベイ幕張ホール(千葉県千葉市)
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] Identification of the primary functional variants for Primary biliary cirrhosis (PBC) susceptibility loci by high-density association mapping and in silico / in vitro functional analyses.2016

    • Author(s)
      Hitomi Y, Kojima K, Kawashima M, Kawai Y, Nishida N, Aiba Y, Yasunami M, Nagasaki M, Nakamura M, Tokunaga K
    • Organizer
      American Society of Human Genetics 2017 Annual Meeting
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2016-10-18
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] 日本人原発性胆汁性肝硬変(PBC)の発症と関連する機能的遺伝子多型(casual variant)の同定2016

    • Author(s)
      人見祐基,中村 稔
    • Organizer
      第52回 日本肝臓学会総会
    • Place of Presentation
      ホテルニューオオタニ幕張 東京ベイ幕張ホール(千葉県千葉市)
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] Identification of the casual variants in human primary biliary cirrhosis (PBC) by the combination of a genome-wide association study, Whole-genome sequencing, and in silico/ in vitro functional analyses.2016

    • Author(s)
      HITOMI Yuki, AIBA Yoshihiro, YASUNAMI Michio, NAKAMURA Minoru, TOKUNAGA Katsushi.
    • Organizer
      第45回 日本免疫学会総会
    • Place of Presentation
      沖縄コンベンションセンター ラグナガーデンホテル(沖縄県宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 統合データベースを活用した肝・胆道系の難治性疾患”原発性胆汁性胆管炎”の疾患関連遺伝子解析2016

    • Author(s)
      中村 稔
    • Organizer
      トーゴーの日 シンポジウム2016
    • Place of Presentation
      東京大学弥生講堂 一条ホール(東京都文京区)
    • Year and Date
      2016-10-05
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] Genome-wide association study identifies PRKCB as a novel genetic factor for primary biliary cirrhosis in the Japanese population.2016

    • Author(s)
      M. Kawashima, Y. Hitomi, N. Nishida, K. Kojima, Y. Kawai, H. Nakamura, M. Yasunami, K. Chayama, Y. Aiba, M. Nagasaki, K. Tokunaga, M. Nakamura, PBC Consortium in Japan (PBCCSJ)
    • Organizer
      The 66th American Society of Human Genetics Annual Meeting
    • Place of Presentation
      Vancouver(Canada)
    • Year and Date
      2016-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] Identification of the primary functional variants for primary biliary cirrhosis (PBC) susceptibility loci by high-density association mapping and in silico/in vitro functional analyses.2016

    • Author(s)
      Y. Hitomi, K. Kojima, M. Kawashima, Y. Kawai, N. Nishida, Y. Aiba, M. Yasunami, M. Nagasaki, M. Nakamura, K. Tokunaga
    • Organizer
      The 66th American Society of Human Genetics Annual Meeting
    • Place of Presentation
      Vancouver(Canada)
    • Year and Date
      2016-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 日本人における自己免疫性肝炎発症に関わる遺伝要因2016

    • Author(s)
      樋口貴士,岡 笑美,古川 宏,小森敦正,八橋 弘,中村 稔,川崎 綾,土屋尚之,右田清志
    • Organizer
      第44回 日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] Imputation analysis using reference panel of 1,070 Japanese individuals (1KJPN) and in silico / in vitro functional analyses identified functional variants for primary biliary cirrhosis (PBC) susceptibility.2016

    • Author(s)
      Yuki Hitomi, Kaname Kojima, Minae Kawashima, Yosuke Kawai, Nao Nishida, Yoshihiro Aiba, Michio Yasunami, Masao Nagasaki, Minoru Nakamura, Katsushi Tokunaga.
    • Organizer
      第13回 国際人類遺伝学会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 原発性胆汁性肝硬変における TL1A の役割 ワークショップ 6; 自己免疫性肝疾患の病態と治療2015

    • Author(s)
      相葉佳洋, 小森敦正, 中村 稔
    • Organizer
      第41回日本肝臓学会西部会
    • Place of Presentation
      名古屋 国際会議場
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 原発性胆汁性肝硬変(PBC)感受性遺伝子 TNFSF15 に存在する rs4979462 は, NF1結合を介したTNFSF15 発現量の亢進に寄与する2015

    • Author(s)
      人見祐基, 相葉佳洋, 西田奈央, 中村 稔
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本 ホテルキャッスル
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 日本人原発性胆汁性肝硬変の疾患感受性遺伝子による病態の解明 シンポジウム1; PBC(原発性胆汁性肝硬変)-臨床、病理と免疫学との接点を求めて2015

    • Author(s)
      中村 稔, 川嶋実苗, 相葉佳洋, 西田奈央, 人見祐基, 小森敦正, 下田慎治, 田中 篤, 茶山一彰, 太平弘正, 山本和秀, 銭谷幹男, 小島 要, 長崎正朗, 徳永勝士
    • Organizer
      第52回日本消化器免疫学会総会
    • Place of Presentation
      東京 京王プラザホテル
    • Year and Date
      2015-07-30
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] Dissection of HLA class II in Japanese primary biliary cirrhosis: epistasis of protective HLA-DQ allele and additional contribution of HLA-DP allele.2015

    • Author(s)
      M. Yasunami; H. Nakamura; K. Tokunaga; M. Kawashima; N. Nishida; Y. Hitomi; M. Nakamura
    • Organizer
      American Society of Human Genetics 2015
    • Place of Presentation
      Baltimore (U.S.A.)
    • Year and Date
      2015-10-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] ゲノムワイド関連解析から同定された日本人原発性胆汁性肝硬変症発症に抑制的なHLAハプロタイプの効果2015

    • Author(s)
      安波道郎, 中村 仁美, 徳永勝士, 川嶋実苗, 西田奈央, 人見祐基, 中村 稔
    • Organizer
      日本人類遺伝学会第60回大会
    • Place of Presentation
      東京 京王プラザホテル
    • Year and Date
      2015-10-15
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] ゲノムワイド関連解析から同定された日本人原発性胆汁性肝硬変症発症に抑制的な HLA ハプロ タイプの効果2015

    • Author(s)
      安波 道郎、中村 仁美、徳永 勝士、川嶋 実苗、西田 奈央、人見 祐基、中村 稔
    • Organizer
      第 60 回日本人類遺伝学会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K06908
  • [Presentation] 日本人原発性胆汁性肝硬変の新規疾患感受性遺伝子PRKCB, ETS1の同定2015

    • Author(s)
      相葉佳洋, 川嶋美苗, 西田奈央, 人見祐基, 小森敦正, 茶山一彰, 安波道郎, 徳永勝士, 中村 稔
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本 ホテルキャッスル
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 日本人原発性胆汁性肝硬変の疾患関連遺伝子の同定.2014

    • Author(s)
      中村 稔
    • Organizer
      第50回日本肝臓学会総会.
    • Place of Presentation
      ホテルニューオオタニ(東京都千代田区)
    • Year and Date
      2014-05-29
    • Data Source
      KAKENHI-PROJECT-26293181
  • [Presentation] 原発性胆汁性肝硬変におけるFractalkine発現とursodeoxycholic acidによる発現制御2013

    • Author(s)
      原田憲一、佐藤裕英、中村 稔、中沼安二
    • Organizer
      第49回日本肝蔵学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] ヒト胆管上皮細胞におけるTL1A産生機構の解析2013

    • Author(s)
      相葉佳洋、小森敦正、伊東正博、右田清志、八橋 弘、中村 稔
    • Organizer
      第41回日本臨床免疫学会
    • Place of Presentation
      下関
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] WHO MAY HAVE TREATMENT BENEFITS WITH FIBRATES IN PRIMARY BILIARY CIRRHOSIS : A SINGLE CENTER RETROSPECTIVE OBSERVATIONAL COHORT ANALYSIS2013

    • Author(s)
      A. Komori, M. Nakamura, Y. Aiba, Y. Kugiyama-Yasunaga, S. Bekki, R. Sasaki, S. Hashimoto, M. Ootani, S.-K. Bae, A. Saeki, S. Nagaoka, S. Abiru, K. Yamasaki, H. Ishibashi, H. Yatsuhashi
    • Organizer
      48th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Amsterdam, The Netherlands
    • Year and Date
      2013-04-26
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の疾患感受性遺伝子による病態の解明2013

    • Author(s)
      中村 稔、西田奈央、徳永勝士
    • Organizer
      第49回日本肝蔵学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] The mechanism of TL1A production in human biliary epithelial cells.2013

    • Author(s)
      Yoshihiro Aiba, Atsumasa Komori, Masahiro Ito, Kiyoshi Migita, Hiroshi Yatsuhashi, Minoru Nakamura.
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張、千葉
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] Genetic polymorphisms in CYP7A1 and PPARGC1A affcts the progression of primary biliary cirrhosis via the altered expression of CYP71A.2013

    • Author(s)
      Tatsuo Inamine, Minoru Nakamura, Chi Zhu, Shinji Kondo, Kazuhiro Tsukamoto.
    • Organizer
      AASLD THE LIVER MEETING 2013
    • Place of Presentation
      Washington, DC, USA
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変(PBC)の疾患感受性遺伝子による病態の解明2013

    • Author(s)
      中村 稔、西田奈央、徳永勝士
    • Organizer
      第17回日本肝臓学会・第55回日本消化器病学会合同大会
    • Place of Presentation
      品川
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変患者におけるTLIAの役割2013

    • Author(s)
      相葉佳洋, 原田憲一, 小森敦正, 伊東正博, 阿比留正剛, 長岡進矢, 石橋大海, 中沼安二, 八橋弘, 中村稔
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2013-06-06
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] Systemic and local expression of TNF-like ligand 1A and its decoy receptor 3 are increased in primary biliary cirrhosis.2013

    • Author(s)
      Yoshihiro Aiba, Kenichi Harada, Atsumasa Komori, Masahiro Ito, Shinji Shimoda, Shinya Nagaoka, Seigo Abiru, Kiyoshi Migita, Hiromi Ishibashi, Yasuni Nakanuma, Nao Nishida, Minae Kawashima, Katsushi Tokunaga, Hiroshi Yatsuhashi, Minoru Nakamura.
    • Organizer
      AASLD THE LIVER MEETING 2013
    • Place of Presentation
      Washington, DC, USA
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変(PBC)の疾患感受性遺伝子による病態の解明 シンポジウム4 炎症性疾患と再生のゲノム、エピゲノム解析の現状と展望2013

    • Author(s)
      中村 稔
    • Organizer
      第34回日本炎症・再生医学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の肝局所におけるTL1A産生機構の解明2013

    • Author(s)
      相葉佳洋、原田憲一、小森敦正、阿比留正剛、長岡進矢、右田清志、伊東正博、中沼安二、八橋 弘、中村 稔
    • Organizer
      第50回日本消化器免疫学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変におけるTL1Aの役割2013

    • Author(s)
      相葉佳洋、原田憲一、小森敦正、阿比留正剛、長岡進矢、右田清志、石橋大海、中沼安二、八橋 弘、中村 稔
    • Organizer
      第49回日本肝蔵学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の進行に関与する胆汁酸合成系遺伝子多型の解析2013

    • Author(s)
      稲嶺達夫、大曲勝久、中村 稔
    • Organizer
      第49回日本肝蔵学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変のゲノムワイド関連解析2012

    • Author(s)
      中村 稔, 西田奈央, 川嶋実苗, 田中 篤, 中牟田 誠, et al
    • Organizer
      第48回 日本肝臓学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 1) Roles of a choline uptake transporter, the organic cation transporter 1 (OCT1), in pathogenesis of primary biliary cirrhosis: OCT1 expression and its single-nucleotide polymorphism.2012

    • Author(s)
      Kohjima M, Ohishi Y, Fukushima N, Nakamura T, Kurokawa M, et al,
    • Organizer
      63rd AASLD
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変の病態形成に関与するHLA-A,-B,-DP,-DR遺伝子多型とCTLA-4, SLC4A2, IL12A, IRF5遺伝子多型の検討2012

    • Author(s)
      相葉佳洋, 安波道郎, 小森敦正, 右田清志, 八橋弘, 中牟田誠, 福嶋伸良, 太田肇, 石田仁也, 平田啓一, 渡部幸夫, 小松達司, 矢倉道泰, 高野弘嗣, 室豊吉, 島田昌明, 米田俊貴, 山下晴弘, 竹崎英一, 古賀満明, 小林正和, 杉和洋, 正木尚彦, 古澤要, 蒔田富士雄, 高木均, 西村英夫, 石橋大海, 中村稔
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の治療におけるフィブレート製剤の効果と限界2012

    • Author(s)
      小森敦正, 中村稔, 伊東正博, 釘山有希, 戸次鎮宗, 福島真典, 橋元悟, 大谷正史, 裵成寛, 佐伯哲, 長岡進矢, 阿比留正剛, 八橋弘, 石橋大海
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] Signal Transducer and Activator of Transcription 4 遺伝子多型と日本人の原発性胆汁性肝硬変発症に関する検討2012

    • Author(s)
      城下 智, 梅村武司, 中村 稔
    • Organizer
      第48回 日本肝臓学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 2) Signal transducer and activator of transcription 4 gene polymorphisms are associated with production of antinuclear antibody in Japanese patients with primary biliary cirrhosis.2012

    • Author(s)
      Joshita S, Umemura T, Nakamura M, Katsuyama Y, Yoshizawa K, et al
    • Organizer
      63rd AASLD
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変のゲノムワイド関連解析2012

    • Author(s)
      中村稔, 西田奈央, 川嶋実苗, 田中篤, 中牟田誠, 太田肇, 竿代丈夫, 高野弘嗣, 吉澤要, 小森敦正, 梅村武司, 銭谷幹男, 恩地森一, 橋本悦子, 大平弘正, 山本和秀, 金子周一, 山際訓, 中尾一彦, 市田隆文, 滝川一, 前原喜彦, 上本伸一, 國土典宏, 坪内博仁, 溝上雅史, 徳永勝士, 中沼安二, 石橋大海
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変症の病態形成におけるorganic cation transporter 1の重要性2012

    • Author(s)
      中牟田誠, 国府島庸之, 大石裕樹, 中村稔, 吉本剛志, 山崎晃裕, 中村吏, 福嶋伸良, 福泉公仁隆, 石橋大海, 本多彰, 野崎雄一, 松﨑靖司, 中島淳, 遠城寺宗近
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の自己抗体、病理学的スコア、治療反応性と予後の相関解析.2011

    • Author(s)
      中村 稔、伊東正博、山本和秀、大平弘正、銭谷幹男、田中 篤、橋本悦子、本多政夫、金子周一、上野義之、菊池健太郎、下田慎治、小森敦正、原田憲一、向坂彰太郎、滝川 一、恩地森一
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] Positive Anti-GP210 Antibodies is a Risk Factor for Poor Biochemical Response to Ursodeoxycholic Acid Treatment in Japanese Patients with Primary Biliary Cirrhosis. 46th Annual Meeting of the European Association for the Study of the Liver2011

    • Author(s)
      M. Nakamura, M. Ito, K. Yamamoto, M. Zeniya, H. Ohira, E. Hashimoto, M. Honda, S. Kaneko, Y. Ueno, K. Kikuchi, S. Onji, S. Shimoda, H. Takikawa, A. Tanaka, A. Komori, H. Yatsuhashi, H. Kondo, K. Harada, S. Onishi, H. Tsubouchi, Y. Nakanuma, H. Ishibashi
    • Organizer
      The International Liver Congress 2011
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の病態に準拠した治療方針;当科における後ろ向き解析2011

    • Author(s)
      小森敦正,中村稔,釘山有希,戸次鎮宗,福島真典,橋元悟,大谷正史,裵成寛,佐伯哲,長岡進矢,阿比留正剛,八橋弘,伊東正博,石橋大海
    • Organizer
      第98回日本消化器病学会九州支部例会,第92回日本消化器内視鏡学会九州支部例会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変におけるCTLA4,IL12A,IL12RB2,IRF5,染色体17q12-21領域の遺伝子多型の解析2011

    • Author(s)
      相葉佳洋、城下 智、吉澤 要、梅村武司、小森敦正、右田清志、八橋 弘、石橋大海、中村 稔
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変(PBC)における病因病態の解析2011

    • Author(s)
      下田慎治、中村 稔、石橋大海
    • Organizer
      第15回日本肝臓学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変におけるIL12A,IL12RB2,IRF5,染色体17q12-21領域の遺伝子多型の解析2011

    • Author(s)
      相葉佳洋、小森敦正、右田清志、八橋 弘、石橋大海、中村 稔
    • Organizer
      第48回日本消化器免疫学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 国立病院機構肝疾患共同研究グループにおける原発性胆汁性肝硬変合併肝細胞癌2011

    • Author(s)
      小森敦正,中村稔,阿比留正剛,八橋弘,藤岡ひかる,石橋大海
    • Organizer
      第47回日本肝癌研究会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変において抗gp210抗体および抗セントロメア抗体は薬物治療効果の予測因子となり得るか2011

    • Author(s)
      福嶋伸良、中村 稔、福泉 公仁隆、吉本剛志、國府島 庸之、後藤 和人、河邉 顕、水谷 孝弘、小森敦正、原田直彦、中牟田誠、石橋大海、佐田通夫
    • Organizer
      第15回日本肝臓学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の自己抗体,病理学的スコア,治療反応性と予後の相関解析2011

    • Author(s)
      中村稔,伊東正博,山本和秀,太平弘正,銭谷幹男,田中篤,橋本悦子,本多政夫,金子周一,上野義之,菊池健太郎,下田慎治,小森敦正,原田憲一,向坂彰太郎,滝川一,恩地森一,西原利治,大西三朗,坪内博仁,中沼安二,石橋大海
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変における免疫関連分子の遺伝子多型の解析2011

    • Author(s)
      相葉佳洋,稲嶺達夫,城下智,小森敦正,右田清志,八橋弘,中牟田誠,福嶋伸良,竿代丈夫,林茂樹,渡部幸夫,矢倉道泰,高野弘嗣,室豊吉,太田肇,島田昌明,米田俊貴,山下晴弘,竹崎英一,古賀満明,小松達司,小林正和,杉和洋,高橋正彦,正木尚彦,吉澤要,塚元和弘,石橋大海,中村稔
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変のOCT-1遺伝子の多型解析2011

    • Author(s)
      大石裕樹、石川奈緒子、石橋 誠、福嶋伸良、中牟田誠、相葉佳洋、小森敦正、石橋大海、中村 稔
    • Organizer
      第20回西日本臨床胆汁酸研究会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] ヒト肝内胆管細胞におけるSignal tranaducer and activator of transcription 3/5の役割2010

    • Author(s)
      小森敦正、相葉佳洋、中村稔、藤原紳祐、藤岡ひかる、右田清志、八橋弘、石橋大海
    • Organizer
      第46回日本肝臓学会総会(肝臓 51巻 2010, suppl.(1), A264)
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Signal Transducer and activator of transcription and 5 : Distinct regulators in growth and differentiation of human cholangiocyte in vitro.2010

    • Author(s)
      Komori A, Aiba Y, Nakamura M, Fujiwara S, Migita K, Fujioka H, Yatsuhashi H, Ishibashi H
    • Organizer
      EASL The International Liver Congress 2010 (A952)
    • Place of Presentation
      Vienna
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Positive anti-gp210 antibodies is a strong risk factor for bile duct loss and hepatitis which induce jaundice-type progression of primary biliary cirrhosis in Japanese patients2010

    • Author(s)
      Nakamura M, Ito M, Zeniya M, Ohira H, Hashimoto E, Kaneko S, Ueno Y, Kikuchi K, et al
    • Organizer
      EASL The International Liver Congress 2010
    • Place of Presentation
      Vienna, Austria
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Positive anti-gp210 antibodies is a strong risk factor for bile duct loss and hepatitis which induce jaundice-type progression of primary biliaruy cirrhosis in Japanese patients.2010

    • Author(s)
      Nakamura M, Ito M, Zeniya M, Ohira H, Hashimoto E, Kaneko S, Ueno Y, Kikuchi K, Onji M,Shimoda S, Komori A, Takikawa H, Onishi S, Tsubouchi H, Ishibashi H, Nakanuma Y
    • Organizer
      EASL The International Liver Congress 2010 (A1109)
    • Place of Presentation
      Vienna
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変(PBC)における免疫異常の基礎とそれに基づく予後予測について2010

    • Author(s)
      下田慎治、中村稔、石橋大海
    • Organizer
      第14回日本肝臓学会大会(肝臓 51巻 2010, suppl.(2), A435.)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変との関連が報告されている遺伝子多型の日本人でのreplication study.2010

    • Author(s)
      相葉佳洋、小森敦正、長岡進矢、阿比留正剛、右田清志、八橋弘、石橋大海、齋藤晃、中牟田誠、矢倉道泰、高野弘嗣、林茂樹、小松達司、渡部幸夫、小林正和、杉和洋、太田肇、島田昌明、米田俊貴、古賀満明、山下晴弘、竹崎英一、佐藤丈顕、高橋正彦、酒井浩徳、山本哲夫、正木尚彦、中村稔
    • Organizer
      第46回日本肝臓学会総会(肝臓 51巻 2010, suppl.(1), A342)
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変における抗gp210抗体測定の意義の検証2010

    • Author(s)
      中村稔、伊東正博、山本和秀、銭谷幹男、大平弘正、橋本悦子、金子周一、上野義之、菊池健太郎、恩地森一、下田慎治、小森敦正、滝川一、大西三朗、坪内博仁、中沼安二、石橋大海
    • Organizer
      第46回日本肝臓学会総会(肝臓 51巻 2010, suppl.(1), A62.)
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Analysis of HLA-DRB1 polymorphism in Japanese patients with primary biliary cirrhosis (PBC) - HLA-DRB1 polymorphism determines the relative risk of anti-nuclear antibodies for the disease-progression in PBC.2009

    • Author(s)
      Nakamura M, Yasunami M, Kondo H, Aiba Y, Komori A, Migita K, Yatsuhashi H, Nakamuta M, Hayashi S, Saito A, Honda K, Shimada M, Watanabe Y, Yagura M, Kohno H, Sugi K, Ota H, Komatsu T, Mannami T, Koga M, Satoh T, Takesaki E, Yamamoto T, Oohara Y, Masaki N, Ishibasi H
    • Organizer
      Hepatology(Volume 50, Number 4 (Suppl), October 2009, 1004A, 1521.)
    • Place of Presentation
      Boston
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変の予後診断法の確立のための遺伝子解析2009

    • Author(s)
      中村稔、塚元和弘、安波道郎、近藤久義、相葉佳洋, 小森敦正、右田清志、八橋弘、竿代丈夫、林茂樹、中牟田誠、本田浩一、杉和洋、島田昌明、小林正和、渡部幸夫、森本日出雄、矢倉道泰、正木尚彦、高野弘嗣、竹崎英一、小松達司、山下晴弘、加藤道夫、古賀満明、長岡進矢、矢野公士、阿比留正剛、石橋大海
    • Organizer
      第45回日本肝臓学会総会(肝臓 50巻 2009, suppl.(1), A162, 0-78.)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Analysis of HLA-DRB1 polymorphism in Japanese patients with primary biliary cirrhosis-HLA-DRB1 polymorphism determines the relative risk of anti-nuclear antibodies for the disease-progression in PBC.2009

    • Author(s)
      Nakamura M, Yasunami M, Kondo H, Aiba Y, Komori A, et al.
    • Organizer
      AASLD
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 日本人原発性胆汁性肝硬変(PBC)患者のCTLA-4一塩基多型(SNP)の解析2009

    • Author(s)
      相葉佳洋、中村稔、小森敦正、右田清志、八橋弘、塚本和弘、石橋大海
    • Organizer
      第46回日本消化器免疫学会総会
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] HLA-DRB1遺伝子多型が抗核抗体による原発性胆汁性肝硬変の予後予測に及ぼす影響の検討2009

    • Author(s)
      中村稔、安波道郎、近藤久義、相葉佳洋、小森敦正、長岡進矢、阿比留正剛、八橋弘、右田清志、石橋大海
    • Organizer
      第46回日本消化器免疫学会総会
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] PBC患者における血清BAFFの測定2009

    • Author(s)
      右田清志、中村稔、阿比留正剛、小森敦正、矢野公士、八橋弘、石橋大海
    • Organizer
      第45回日本肝臓学会総会(肝臓 50巻 2009, suppl.(1), A392, P-293.)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変における慢性非化膿性破壊性胆管炎の場で特異的発現を示すケモカイン、特にCX3CL1の産生機序と自然免疫の関与2009

    • Author(s)
      下田慎治、中村稔、石橋大海
    • Organizer
      第17回浜名湖シンポジウム
    • Place of Presentation
      浜松
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 当科におけるPBC-AIH overlap症候の特徴と予後2009

    • Author(s)
      小森敦正, 中村稔、本吉康英、橋元悟、裴成寛、立山雅邦、長岡進矢、柳謙二、田浦直太、阿比留正剛、矢野公士、右田清志、八橋弘、石橋大海
    • Organizer
      第45回日本肝臓学会総会(肝臓 50巻 2009, suppl.(1), A391,P-291.)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Hepatic expression of peroxisome proliferators activated receptors A(PPARA) in primary biliary cirrhosis.2009

    • Author(s)
      Nakamura M, Ito M, Aiba Y, Komori A, Migita K, Yatsuhashi H, Ishibashi H
    • Organizer
      Nuclear Receptors and Liver Disease.(Abstract page 87.)
    • Place of Presentation
      Vienna
    • Year and Date
      2009-02-28
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Identification of serological and genetic biomarkers for predicting the prognosis of primary biliary cirrhosis (PBC)2008

    • Author(s)
      Nakamura M, Ohishi Y, Iio N, Aiba Y, Komori A, et al
    • Organizer
      The 59th Annual Meeting of The American Association for the Study of Liver Diseases (A ASLD)
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] OSTEOPONTIN, A PUTATIVE MARKER FOR DUCTULAR REACTION, IS INDUCED BY JAK/STAT3 ACTIVATION IN HUMAN BILIARY EPITHELIAL CELLS.2008

    • Author(s)
      Komori A, Uemura T, Fujiwara S, Aiba Y, Nakamura M, et al
    • Organizer
      The 43rd Annual Meeting of the European Association For the Study of the Liver.
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Redefining AMA negative primary biliary cirrhosis : CD4 T cell autoreactivity to the dominant mitochondrial autoantigen PDC-E2.2008

    • Author(s)
      Shimoda S, Miakawa H, Nakamura M, Ishibashi H, Kikuchi K, et al
    • Organizer
      The 59th Annual meeting of The American Association for the Study of Liver Diseases (AASLD).
    • Place of Presentation
      San Francisco
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Identification of serological and genetic biomarkers for predicting the prognosis of primary biliary cirrhosis (PBC). -A homozygous "Hap2/Hap2" diplotype in multidrug resistance protein 3 (MDR3) gene confers a strong susceptibility to jaundice-type progression of PBC-2008

    • Author(s)
      Nakamura M, Ohishi Y, Iio N, Aiba Y, Komori A, et al
    • Organizer
      The 59th Annual Meeting of The American Association for the Study of Liver Diseases (AASLD).
    • Place of Presentation
      San Francisco
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変の予後予測診断法の確立2008

    • Author(s)
      中村稔, 大石裕樹, 相葉佳洋, 小森敦正, 右田清志, 八橋弘, 竿代丈夫, 中牟田誠, 本田浩一, 島田昌明, 小林正和, 渡部幸夫, 林茂樹, 古賀満明, 森本日出雄, 正木尚彦, 近藤久義, 大曲勝久, 安波道郎, 塚元和弘, 石橋大海
    • Organizer
      第44回日本肝臓学会総会(肝臓 49巻 2008, suppl.(1), A184, 0-115.)
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 培養ヒト肝内胆管上皮細胞の急性相反応からみた遺伝子発現の可能性2008

    • Author(s)
      小森敦正, 植村隆, 藤原紳祐, 相葉佳洋, 中村稔, 矢野公士, 藤岡ひかる, 右田清志, 八橋弘, 石橋大海
    • Organizer
      第44回日本肝臓学会総会(一般演題,セッション60:胆管・胆汁うっ滞2)(肝臓 49 Suppl.(1):A235,2008.04.30)
    • Place of Presentation
      愛媛
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Autoantibody status and histological variables influence biochemical response to treatment and long-term outcomes in Japanese patients with primary biliary cirrhosis.

    • Author(s)
      Minoru Nakamura
    • Organizer
      EASL Monothematic Conference: Primary Biliary Cirrhosis (PBC) .
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2014-05-23 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26293181
  • []

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  • 1.  ISHIBASHI Hiromi (80127969)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 123 results
  • 2.  NAKANO Shuji (40164248)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 3.  HAYASHIDA Kazuhiro (60180981)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  YATSUHASHI Hiroshi (50360855)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 13 results
  • 5.  AIBA Yoshihiro (70450955)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 73 results
  • 6.  ITO Masahiro (30184691)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 39 results
  • 7.  KOMORI Atumasa (50234901)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 111 results
  • 8.  SHIMODA Shinji (30279319)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 32 results
  • 9.  FUJIOKA Hikaru (00264226)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 10.  MIGITA Kiyoshi (60264214)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 40 results
  • 11.  KAWASHIMA Minae (00396706)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 27 results
  • 12.  NISHIDA Nao (50456109)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 17 results
  • 13.  NISHIMURA Yasuharu (10156119)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  MITSUGI Kenji (20315063)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  人見 祐基 (10525819)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 29 results
  • 16.  NAGAFUCHI Seiho (00150441)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  KUDO Jiro (90148940)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  FUKUI Yoshinori (60243961)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  YANO Koji (60360856)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  岡村 精一 (20136435)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  出原 賢二 (00270463)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  安波 道郎 (80244127)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 24.  馬場 英司
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  HIRATA Yasuhiko (10218787)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MATSUSHITA Sho (50167649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  TOKUNAGA Katsushi (40163977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 28.  吉良 潤一 (40183305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  喜多 宏人 (80294974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  高槻 光寿 (80380939)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 31.  原田 憲一 (30283112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 32.  有田 誠 (80292952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  吉住 朋晴 (80363373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 34.  小島 要 (10646988)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 35.  植野 和子 (00794512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 36.  長崎 正朗 (90396862)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  NAKANE Shunya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  TOUMA Shigeto
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  池上 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  調 憲
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  樋口 理
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  築地 信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  山本 健
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  川合 覚
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  古川 宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  土屋 尚之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  梅村 武司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  太田 正穂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  河合 洋介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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