saeki yukihiko 佐伯行彦

… Alternative Names

Saeki Yukihiko 佐伯行彦

SAEKI Yukihiko 佐伯行彦

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Researcher Number	40240840
Affiliation (Current)	2025: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), その他部局等, 流動研究員
Affiliation (based on the past Project Information) *help	2017 – 2019: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), その他部局等, 部長 2017: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), その他部局等, 臨床研究部長 2016 – 2017: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), 臨床研究部, 部長 2015: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), 臨床研究部, 臨床研究部長 2006: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), 部長 … More 2006: National Hospital Organization Osaka Minami Medical Center, Department of Clinical Research, Director, 臨床研究部, 部長 2002: Osaka University Graduate School Of Medicine Lecturer, 医学系研究科, 講師 2001: 大阪大学, 医学系研究科, 助手 1992 – 1997: 大阪大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Collagenous pathology/Allergology / 内科学一般 / Immunology Except Principal Investigator Human pathology / 膠原病・アレルギー・感染症内科学 / Biological Sciences
Keywords	Principal Investigator NFIL-6 / 関節リウマチ / 慢性関節リウマチ / TNF / 生物学的製剤 / NF-kB / AhR / TNF阻害薬 / クロストーク / ＡｈＲ … More / NF-ｋB / 喫煙 / ＴＮＦ阻害薬 / Knock out mouse / Transcriptional factor / Rheumatoid arthritis / COX / ノックアウトマウス / 転写因子 / NF-IL6 / 免疫不全マウス / 原因抗原 / T細胞レセプター / 滑膜炎 / T細胞 / RA / SCID … More Except Principal Investigator HIV coreceptor / SDF-1 / CD40 / NF-IL6 / STAT3 / gp130 / メトトレキサート / 悪性リンパ腫 / リンパ増殖性疾患 / 関節リウマチ / Japonica array / SNPs / GWAS / MTX-LPD / Malignant lymphoma / LPD / Methotrexate / Rheumatoid arthritis / galectin3 / retroelement / ガレクチン-3 / レトロエレメント / chemokine PBSF / サイトカインシグナル伝達 / 自己免疫病 / SCIDマウス / CD23 / APRF / サイトカイン / リウマチ / キャッスルマン病 / ノックアウトマウス / STAT6 / IL-6レセプター / ケモカインPBSF Less

Analysis of the genetic predictor to the onset of MTX-LPD for the genomic medicine
- Principal Investigator
  
  Hoshida Yoshihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  National Hospital Organization Osaka-Minami Medical Center
The influence of smoking on biologics treatment in rheumatoid arthritis and its possible molecular mechanism.Principal Investigator
- Principal Investigator
  
  Saeki Yukihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  National Hospital Organization Osaka-Minami Medical Center
The role of retroelement in rheumatoid arthritis
- Principal Investigator
  
  OHSHIMA Shiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  National Hospital Organization Osaka Minami Medical Center Department of Clinical Research
NFIL-6(C/EBPβ)Principal Investigator
- Principal Investigator
  
  SAEKI Yukihiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Osaka University
慢性関節リウマチ(RA)における原因となる抗原ペプチドの特定Principal Investigator
- Principal Investigator
  
  佐伯行彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
免疫病の分子・遺伝子治療に関する研究
- Principal Investigator
  
  KISHIMOTO Tadamitsu
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
SCID(Severe Combined Immuucdeficiency)マウスを用いたRA(慢性関節リウマチ)モデルの作製とそのモデルを用いたRAの病因・病態の解析Principal Investigator
- Principal Investigator
  
  佐伯行彦
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University

All 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Sporotrichal Tenosynovitis Diagnosed Helpfully by Musculoskeletal Ultrasonography2017
- Author(s)
  Shimizu T, Akita S, Harada Y, Oguro E, Okita Y, Shigesaka M, Matsuoka H, Nii T, Teshigawara S, Kudo-Tanaka E, Tsuji S, Matsushita M, Ohshima S, Hoshida Y, Hashimoto J, Saeki Y.
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 10 Pages: 1243-1246
- DOI
  10.2169/internalmedicine.56.7912
- NAID
  130006858082
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08734
[Journal Article] Safety and efficacy of CT-P13 in Japaneses patients with rheumatoid arthritis in an extension phase or after switching from infliximab.2017
- Author(s)
  Tanaka Y, Yamanaka H, Takeuchi T, Inoue M, Saito K, Saeki Y, Lee SJ, Nambu Y.
- Journal Title
  
  Modern Rheumatology
  
  Volume: 27 (2) Pages: 237-45
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09544
[Journal Article] Dysbiosis contributes to arthritis development via activation of autoreavtive T cells in the intestine.2016
- Author(s)
  Maeda Y, Kurakawa T, Umemoto E, Motooka D, Ito Y, Gotoh K, Hirota K, Matsushita M, Furuta Y, Narazaki M, Sakaguchi N, Kayama H, Nakamura S, Iida T, Saeki Y, Kumanogoh A, Sakaguchi S, Takeda K.
- Journal Title
  
  Arthritis Rheumatology
  
  Volume: 68 (11) Pages: 2646-61
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09544
[Journal Article] Low rates of biologic-free clinical disease activity index remission maintenance after biologic disease-modifying anti-rheumatic drug discontinuation while in remission in a Japanisese multicenter rheumatoid arthritis registry.2016
- Author(s)
  Yoshida K, Kishimoto M, Radner H, Matsui K, Okada M, Saeki Y, Solomon DH, Tohma S.
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 55(2) Issue: 2 Pages: 286-90
- DOI
  10.1093/rheumatology/kev329
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09544
[Journal Article] Hemophagocytic lymphohistiocytosis with leucoencephalopathy in a aptient with dermatomyosiyis accompanied with peripheral T-cell lymphoma: a cse report.2016
- Author(s)
  Teshigawara S, Katada Y, Maeda Y, Yoshimura M, Kudo-Tanaka E, Tsuji S, Harada Y, Matsushita M, Ohshima S, Watanabe K, Kumode T, Hoshida Y, Saeki Y.
- Journal Title
  
  J Med Case Rep
  
  Volume: 4 (10)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09544
[Journal Article] Elevated soluble CD14-subtype (PRESEPSIN; P-SEP) levels in rheumatoid arthritis (RA) patients with bacterial infection.2016
- Author(s)
  Tsuji S, Kitatoube A, Kikuchi-Taura A, Oguro E, Shigesaka M, Okita Y, Shimizu T, Nii T, Teshigawara S, Tanaka E, Harada Y, Matsushita M, Hashimoto J, Ohshima S, Takahashi G, Endo S, Saeki Y.
- Journal Title
  
  Modern Rheumatology
  
  Volume: Oct27 Pages: 1-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09544
[Journal Article] Early therapeutic intervention with methotrexate prevents the development of rheumatoid arthritis in patients with recent-onset undifferentiated arthritis: A prospective cohort study.2015
- Author(s)
  Kudo-Tanaka E, Shimizu T, Nii T, Teshigawara S, Yoshimura M, Watanabe A, Tsuji S, Tsuboi H, Hirao M, Yura A, Harada Y, Sueishi M, Suenaga Y, Chiba N, Tonai T, Saisho K, Ogata A, Matsushita M, Hashimoto J, Ohshima S, Tohma S, Saeki Y.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 25(6) Issue: 6 Pages: 831-6
- DOI
  10.3109/14397595.2015.1031364
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09544
[Journal Article] Incidence and predictors of biological antirheumatic drugs discontinuation attempts among patinets with rheumatoid arthritis in remission: A CORRONA and NinJa collaborative cohort study.2015
- Author(s)
  Yoshida K, Radner H, Mjaavatten MD, Greenberg JD, Kavanaugh A, Kishimoto M, Matsui K, Okada M, Reed G, Saeki Y, Tohma S, Kremer J, Solomon DH.
- Journal Title
  
  J Rheumatol
  
  Volume: 42(12) Issue: 12 Pages: 2238-46
- DOI
  10.3899/jrheum.150240
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09544
[Journal Article] 1.Semaphorin 4D contributes to rheumatoid arthritis by inducing inflammatory cytokine production: Pathogenic and therapeutic implications2015
- Author(s)
  Yoshida Y, Ogata A, Kang S, Ebina K, Shi K, Nojima S, Kimura T, Ito D, Morimoto K, Nishide M, Hosokawa T, Hirano T, Shima Y, Narazaki M, Tsuboi H, Saeki Y, Tomita T, Tanaka T, Kumanogoh A.
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: none Issue: 6 Pages: 1481-1490
- DOI
  10.1002/art.39086
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861189, KAKENHI-PROJECT-15K08423, KAKENHI-PROJECT-15K09544, KAKENHI-PROJECT-25460495
[Journal Article] Monocyte CD64 expression as a novel biomarker for the disease activity of systemic lupus erythematosus.2015
- Author(s)
  Kikuchi-Taura A, Yura A, Tsuji S, Ohshima S, Kitatoube A, Shimizu T, Nii T, Katayama M, Teshigawara S, Yoshimura M, Kudo-Tanaka E, Harada Y, Matsushita M, Hashimoto J, Saeki Y
- Journal Title
  
  Lupus
  
  Volume: 24(10) Issue: 10 Pages: 1076-80
- DOI
  10.1177/0961203315579093
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09544
[Presentation] SMOKING HABITS INCREASE THERAPEUTIC FAILURE OF BIOLOGICS, SPECIFICALLY TNF-INHIBITORS IN RHEUMATOID ARTHRIIS: A POSSIBLE CROSS-TALK BETWEEN TNFa AND SMOKING (AhR) SIGNALINGS.2018
- Author(s)
  Y. Saeki, et al.
- Organizer
  11th International Congress on Autoimmunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09544
[Presentation] リウマチ患者のリンパ節腫脹に対するリンパ節生検の重要性の検討2017
- Author(s)
  山田知佳 , 小黒英里, 沖田康孝, 重坂実, 葛谷憲太郎, 松岡秀俊, 清水隆, 新居卓朗, 勅使川原悟, 田中枝里子, 原田芳徳, 辻成佳, 辻聡一郎, 秋田鐘弼, 松下正人, 大島至郎, 橋本淳, 佐伯行彦, 星田義彦
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K08734
[Presentation] カルシニューリン阻害剤投与リウマチ患者に発生したリンパ増殖性疾患の4例2017
- Author(s)
  星田義彦, 大島至郎, 佐伯行彦, 川崎明範, 市原周, 金子敦史, 片山雅夫
- Organizer
  第71回国立病院総合医学会
- Data Source
  KAKENHI-PROJECT-17K08734
[Presentation] 関節リウマチに対するメトトレキサート治療中に発生した口腔内メトトレキサート関連リンパ増殖性疾患(MTX-LPD)3例の臨床的・病理学的特徴2017
- Author(s)
  沖田康孝, 松下正人, 星田義彦, 小黒英里, 重坂実, 清水隆, 松岡秀俊, 新居卓朗, 勅使川原悟, 田中枝里子, 原田芳徳, 辻聡一郎, 大島至郎, 橋本淳, 佐伯行彦
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K08734
[Presentation] Smoking signaling enhances TNFa-induced pro-inflammatory cytokine production on a rheumatoid synovial cell line, MH7A.2017
- Author(s)
  Nii T, Oguro E, Okita T, Shimizu T, Matsuoka H, Tsuji S, Tanaka-Kudo E, Teshigawara S, Harada Y, Matsushita M, Ohshima S, Saeki Y.
- Organizer
  The 4th International Congress on Controversies in Rheumatology & Autoimmunity. 9-11 March, 2017, Bologna, Italy.
- Place of Presentation
  Bologna, Italy
- Year and Date
  2017-03-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09544

1. OHSHIMA Shiro (50362728)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. KISHIMOTO Tadamitsu (10093402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OGAWA Hiroyasu (80194447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAGA Tetsuya (40192629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Hoshida Yoshihiko (40324777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 審良静男 (50192919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 徳永勝士 (40163977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 當間重人 (50207528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 古川宏 (00372293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 蛯名耕介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

saeki yukihiko 佐伯 行彦

Saeki Yukihiko 佐伯 行彦

SAEKI Yukihiko 佐伯 行彦

Research Projects

Research Products

Co-Researchers

Analysis of the genetic predictor to the onset of MTX-LPD for the genomic medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The influence of smoking on biologics treatment in rheumatoid arthritis and its possible molecular mechanism.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of retroelement in rheumatoid arthritis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NFIL-6(C/EBPβ)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

慢性関節リウマチ(RA)における原因となる抗原ペプチドの特定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

免疫病の分子・遺伝子治療に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

SCID(Severe Combined Immuucdeficiency)マウスを用いたRA(慢性関節リウマチ)モデルの作製とそのモデルを用いたRAの病因・病態の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sporotrichal Tenosynovitis Diagnosed Helpfully by Musculoskeletal Ultrasonography2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Safety and efficacy of CT-P13 in Japaneses patients with rheumatoid arthritis in an extension phase or after switching from infliximab.2017

Author(s)

Journal Title

Data Source

[Journal Article] Dysbiosis contributes to arthritis development via activation of autoreavtive T cells in the intestine.2016

Author(s)

Journal Title

Data Source

[Journal Article] Low rates of biologic-free clinical disease activity index remission maintenance after biologic disease-modifying anti-rheumatic drug discontinuation while in remission in a Japanisese multicenter rheumatoid arthritis registry.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hemophagocytic lymphohistiocytosis with leucoencephalopathy in a aptient with dermatomyosiyis accompanied with peripheral T-cell lymphoma: a cse report.2016

Author(s)

Journal Title

Data Source

[Journal Article] Elevated soluble CD14-subtype (PRESEPSIN; P-SEP) levels in rheumatoid arthritis (RA) patients with bacterial infection.2016

Author(s)

Journal Title

Data Source

[Journal Article] Early therapeutic intervention with methotrexate prevents the development of rheumatoid arthritis in patients with recent-onset undifferentiated arthritis: A prospective cohort study.2015

Author(s)

Journal Title

DOI

saeki yukihiko 佐伯行彦

Saeki Yukihiko 佐伯行彦

SAEKI Yukihiko 佐伯行彦