MATSUSHITA Natsuki 松下夏樹

… Alternative Names

松下夏樹マツシタナツキ

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Researcher Number	40271556
Other IDs
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Affiliation (Current)	2025: 愛知医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 愛知医科大学, 医学部, 准教授 2014: 愛媛大学, 医学部附属病院, 研究員 2007: Ehime University, Graduate School of Medicine, Assistant Professor 2006: 愛媛大学, 大学院医学系研究科, 特任助手 1999 – 2001: 福島県立医科大学, 医学部, 講師 1998: 奈良先端科学技術大学院大学, 遺伝子教育研究センター, 助手 1995: 理化学研究所, バイオミメティックコントロール研究センター, 研究員
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology / Neurochemistry/Neuropharmacology Except Principal Investigator Transformative Research Areas, Section (III) / Neurochemistry/Neuropharmacology / General medical chemistry / Biological Sciences
Keywords	Principal Investigator ドーパミンニューロン / zinc finger / transcrintional repressor / differentiation / ventral tegmental area / substantia nigra / dopaminereic neurons / Zincフィンガー / KRABドメイン / 発生 … More / Zincフィンガー因子 / 転写抑制因子 / 分化 / 腹側被蓋野 / 黒質 / Imaging / Tyrosine hydroxylase / Neuronal development / Brain culture / Axon guidance / Transgenic mouse / Green fluorescent protein / Dopamine neuron / 軸索ガイド / 中脳 / ドーパミン神経 / イメージング / チロシン水酸化酵素 / 神経発生 / 器官培養 / 軸索ガイダンス / トランスジェニックマウス / GFP / 遺伝子構造 / グリア細胞由来神経栄養因子 / 神経栄養因子 / ドーパミン細胞 … More Except Principal Investigator チロシン水酸化酵素 / ドーパミン / ドーパミン受容体 / 大脳基底核 / 核内受容体 / トランスジェニックマウス / 緑色蛍光タンパク質 / ドーパミンニューロン / 長期記憶 / ノルアドレナリン / 機能操作 / 神経活動 / 遺伝子発現 / 線条体 / 刺激弁別学習 / Cre-loxP system / immunotoxin- medicated cell targeting / nuclear receptor / dopamine receptor / long-term memory / basal ganglia / noradtenaline / dopamine / アドレナリン受容体 / 条件学習 / ドーパミンD2受容体 / 遺伝子ターゲティング / Cre-loxPシステム / イムノトキシン細胞標的法 / TNF-α / Ectodomain Shedding / 細胞膜蛋白質 / TNF-alpha / amphiregulin / HB-EGF / Shedding / レムナントペプチドシグナル / annexin / proTNF-α / proamphiregulin / proHB-EGF / ADAM17 / ectodomian shedding / 介在ニューロン / 間接経路 / 細胞ターゲティング / 組換え体イムノトキシン / 条件的遺伝子ターゲティング / パーキンソン病 / 神経細胞死 / 神経栄養因子 / green fluorescence protein / 軸索ガイダンス / 情動学習 / 運動 Less

Gene and cell function dynamics underlying behavioral adaptation in response to environments
- Principal Investigator
  
  小林和人
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Fukushima Medical University
Regulation of ectodomian shedding by ADAM17 and remnant signaling
- Principal Investigator
  
  HIGASHIYAMA Shigeki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Ehime University
Study of differentiation of midbrain dopaminergic neurons using novel cell type-specific moleculesPrincipal Investigator
- Principal Investigator
  
  MATSUSHITA Natsuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Ehime University
中脳ドーパミンニューロンの発生と生存に関するマウス分子遺伝学的研究
- Principal Investigator
  
  小林和人
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Fukushima Medical University
イムノトキシン細胞標的法を利用した脳情報処理機構の解析
- Principal Investigator
  
  小林和人
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Fukushima Medical University
GFP発現トランスジェニックマウスを利用した選択的神経細胞死の解析
- Principal Investigator
  
  小林和人
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Fukushima Medical University
Molecular and cellular mechanisms underlying catecholaminergic regulation of higher brain functions
- Principal Investigator
  
  KOBAYASHI Kazuto
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Fukushima Medical University
Molecular Mechanism of Axon Guidance during Development of Subtantia Nigra-Striatum PathwayPrincipal Investigator
- Principal Investigator
  
  MATSUSHITA Natsuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Fukushima Medical University
カラコールアミンシグナル伝達系の脳高次機能および神経可塑性における役割の解析
- Principal Investigator
  
  KOBAYASHI Kazuto
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nara Institute of Science and Technology
中枢カテコールアミンニューロンをモデルにした神経回路形成のマウス遺伝学的解析
- Principal Investigator
  
  小林和人
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nara Institute of Science and Technology
ドーパミン作動性神経細胞の発生・分化・生存維持に対する神経栄養因子の機能Principal Investigator
- Principal Investigator
  
  松下夏樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The Institute of Physical and Chemical Research

All 2023 2022 2015

All Journal Article Presentation

[Journal Article] 2. Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence.2023
- Author(s)
  Matsushita, N.*, Kato, S.*, Nishizawa, K., Sugawara, M., Takeuchi, K., Miyasaka, Y., Mashimo, T. and Kobayashi, K. * Equal contribution
- Journal Title
  
  Cell Rep. Methods
  
  Volume: 3 Issue: 2 Pages: 100393-100393
- DOI
  10.1016/j.crmeth.2022.100393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06912, KAKENHI-PLANNED-21H05244, KAKENHI-PROJECT-21H02817, KAKENHI-PROJECT-19K16264, KAKENHI-PROJECT-18KK0307, KAKENHI-ORGANIZER-21H05238, KAKENHI-PUBLICLY-21H00442, KAKENHI-PROJECT-22K20687, KAKENHI-PROJECT-22K19590, KAKENHI-PUBLICLY-22H04786
[Journal Article] 3. Catecholaminergic cell type-specific expression of Cre recombinase in knock-in transgenic rats generated by the Combi-CRISPR technology.2022
- Author(s)
  Matsushita, N., Nishizawa, K., Kato, S., Iguchi, Y., Fukabori, R., Takeuchi, K., Miyasaka, Y., Mashimo, T. and Kobayashi, K.
- Journal Title
  
  J. Neurosci. Methods
  
  Volume: 381 Pages: 109707-109707
- DOI
  10.1016/j.jneumeth.2022.109707
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06912, KAKENHI-PROJECT-22K20687, KAKENHI-PLANNED-21H05244, KAKENHI-PROJECT-21H02817, KAKENHI-PROJECT-19K16264, KAKENHI-PROJECT-18KK0307, KAKENHI-ORGANIZER-21H05238, KAKENHI-PUBLICLY-21H00442, KAKENHI-PROJECT-22K19590
[Journal Article] Cell motion predicts human epidermal stemness.2015
- Author(s)
  Nanba D, Toki F, Tate S, Imai M, Matsushita N, Shiraishi K, Sayama K, Toki H, Higashiyama S, Barrandon Y.
- Journal Title
  
  J Cell Biol.
  
  Volume: 209 Issue: 2 Pages: 305-315
- DOI
  10.1083/jcb.201409024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390074, KAKENHI-PUBLICLY-25112712, KAKENHI-PROJECT-26461660, KAKENHI-PROJECT-26670143, KAKENHI-PROJECT-25293245
[Presentation] Combi-CRISPR技術により作製したカテコールアミン細胞特異的にCre recombinaseを発現するノックインラットの解析2023
- Author(s)
  西澤佳代, 松下夏樹, 加藤成樹, 井口善生, 深堀良二, 武内恒成, 宮坂佳樹, 真下知士, 小林和人
- Organizer
  第43回日本神経科学会
- Data Source
  KAKENHI-PLANNED-21H05244
[Presentation] 高精度な細胞タイプ選択的遺伝子発現を実現するCre-Flex/USSスイッチシステム2023
- Author(s)
  松下夏樹, 西澤佳代, 加藤成樹, 井口善生, 深堀良二, 武内恒成, 宮坂佳樹, 真知士, 小林和人
- Organizer
  第43回日本神経科学会
- Data Source
  KAKENHI-PLANNED-21H05244
[Presentation] Integration of Reward Expectation and Action Selection in the Nigrostriatal System2023
- Author(s)
  Alain Rios, Satoshi Nonomura, Shigeki Kato, Junichi Yoshida, Natsuki Matsushita, Atsushi Nambu, Masahiko Takada, Riichiro Hira, Kazuto Kobayashi, Yutaka Sakai, Minoru Kimura, Yoshikazu Isomura
- Organizer
  第43回日本神経科学会
- Data Source
  KAKENHI-PLANNED-21H05244
[Presentation] Combi-CRISPR技術により作製したカテコールアミン細胞特異的にCre recombinase を発現するTH-Creノックインラットの性状解析2022
- Author(s)
  松下夏樹, 西澤佳代, 加藤成樹, 井口善生, 深堀良二, 武内恒成, 宮坂佳樹, 真下知士, 小林和人
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PLANNED-21H05244

1. KOBAYASHI Kazuto (90211903)

# of Collaborated Projects: 8 results

# of Collaborated Products: 4 results
2. YASOSHIMA Yasunobu (00273566)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HIGASHIYAMA Shigeki (60202272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. FUKUDA Shinji (70398238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. INOUE Hirofumi (70321635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. JHO Takashi (30231369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 瀬戸川将 (30760508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KATO Shigeki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

MATSUSHITA Natsuki 松下 夏樹

松下 夏樹 マツシタ ナツキ

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Study of differentiation of midbrain dopaminergic neurons using novel cell type-specific moleculesPrincipal Investigator

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Molecular Mechanism of Axon Guidance during Development of Subtantia Nigra-Striatum PathwayPrincipal Investigator

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ドーパミン作動性神経細胞の発生・分化・生存維持に対する神経栄養因子の機能Principal Investigator

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[Journal Article] 2. Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence.2023

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DOI

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[Journal Article] 3. Catecholaminergic cell type-specific expression of Cre recombinase in knock-in transgenic rats generated by the Combi-CRISPR technology.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell motion predicts human epidermal stemness.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Combi-CRISPR技術により作製したカテコールアミン細胞特異的にCre recombinaseを発現するノックインラットの解析2023

Author(s)

Organizer

Data Source

[Presentation] 高精度な細胞タイプ選択的遺伝子発現を実現するCre-Flex/USSスイッチシステム2023

Author(s)

MATSUSHITA Natsuki 松下夏樹

松下夏樹マツシタナツキ